Sirenomelia is a rare and lethal condition and its etiopathogenesis is unclear. The diagnosis is based on first trimester ultrasound showing a complete fusion of soft tissue in both lower limbs and other visceral abno...Sirenomelia is a rare and lethal condition and its etiopathogenesis is unclear. The diagnosis is based on first trimester ultrasound showing a complete fusion of soft tissue in both lower limbs and other visceral abnormalities. We report in this article, the misdiagnose of sirenomelia as IUGR leading the other to continue the pregnancy until 35 weeks of gestation.展开更多
Duchenne muscular dystrophy (DMD) is a hereditary, progressive muscular disorder inherited in an X-linked recessive pattern (Xp21). It typically manifests in childhood and follows a severe, rapid progression. Only mal...Duchenne muscular dystrophy (DMD) is a hereditary, progressive muscular disorder inherited in an X-linked recessive pattern (Xp21). It typically manifests in childhood and follows a severe, rapid progression. Only males are affected, while females are usually carriers. Given the genetic nature of DMD, genetic counseling is an essential service for individuals affected by or at risk of carrying the disease. This service provides not only crucial medical information but also psychosocial support and ongoing management for both patients and their families. Since the discovery of the dystrophin gene in 1987, advancements in molecular genetics have made it possible to precisely identify the genes responsible for many neuromuscular diseases. These developments have revolutionized diagnosis, prognosis, and most importantly, genetic counseling, offering significant benefits for both patients and their families. To highlight the significance of these advancements, this case report focuses on a 10-year-old boy (Y) diagnosed with DMD. It emphasizes the familial nature of the disease, with Y’s two brothers, three cousins, and two maternal uncles also affected, underscoring the inherited pattern of DMD. This reinforces the critical need for early intervention, particularly in regions with high consanguinity, such as North Africa and the Middle East, where genetic counseling and prenatal diagnosis are even more essential. Additionally, the report explores the clinical presentation, diagnostic findings, and promising emerging treatments, including RNA-based therapies, which may play a key role in the future management of DMD. In light of the above, this study underscores the importance of prenatal diagnosis and genetic counseling, particularly in regions like Morocco, where consanguinity rates are notably high. By focusing on preconception care and early genetic intervention, families can be better informed, leading to more effective disease management and support.展开更多
Obesity is a significant global health concern, often leading to comorbidities such as cardiovascular diseases, diabetes, and hypertension. Bariatric surgery, including sleeve gastrectomy (SG), is a proven treatment f...Obesity is a significant global health concern, often leading to comorbidities such as cardiovascular diseases, diabetes, and hypertension. Bariatric surgery, including sleeve gastrectomy (SG), is a proven treatment for morbid obesity, offering substantial weight loss and resolution of comorbidities. However, post-surgical complications, particularly anorectal disorders such as hemorrhoids and anal fissures, remain underexplored, especially in Saudi Arabia. This retrospective cohort study aimed to assess the prevalence, risk factors, and impact of anal complications following SG at Almoosa Specialist Hospital in Alhassa, Saudi Arabia. A total of 205 patients who underwent SG between January 2020 and December 2021 were surveyed, with 148 eligible participants included in the final analysis. Results indicated that 8.8% of patients experienced anal complications, with anal fissures (53.8%) and hemorrhoids (38.5%) being the most common. These complications typically occurred 2 - 6 months post-surgery. Lifestyle factors such as physical activity and fluid intake were found to significantly reduce the likelihood of anal issues. Moreover, 69.2% of patients with anal problems reported a negative impact on their quality of life. The study highlights the importance of targeted post-operative care, including lifestyle modifications, to mitigate the impact of anal complications. The findings suggest that ongoing education and comprehensive support for bariatric surgery patients, particularly regarding physical activity and hydration, are critical for improving long-term health outcomes. Further research is needed to explore the long-term progression of anal complications and effective interventions for enhancing patient satisfaction and quality of life.展开更多
In 2012, Ponraj et al. defined a concept of k-product cordial labeling as follows: Let f be a map from V(G)to { 0,1,⋯,k−1 }where k is an integer, 1≤k≤| V(G) |. For each edge uvassign the label f(u)f(v)(modk). f is c...In 2012, Ponraj et al. defined a concept of k-product cordial labeling as follows: Let f be a map from V(G)to { 0,1,⋯,k−1 }where k is an integer, 1≤k≤| V(G) |. For each edge uvassign the label f(u)f(v)(modk). f is called a k-product cordial labeling if | vf(i)−vf(j) |≤1, and | ef(i)−ef(j) |≤1, i,j∈{ 0,1,⋯,k−1 }, where vf(x)and ef(x)denote the number of vertices and edges respectively labeled with x (x=0,1,⋯,k−1). Motivated by this concept, we further studied and established that several families of graphs admit k-product cordial labeling. In this paper, we show that the path graphs Pnadmit k-product cordial labeling.展开更多
Inflammatory fibroid polyps (IFP) are a rare benign entity that arises from the submucosa of the gastrointestinal tract and protrudes into the lumen. The clinical presentation depends on the size and localization. The...Inflammatory fibroid polyps (IFP) are a rare benign entity that arises from the submucosa of the gastrointestinal tract and protrudes into the lumen. The clinical presentation depends on the size and localization. They are particularly found in the ileum, where they are frequently present as an ileal intussusception. We report the case of a 56-year-old female patient who presented with periumbilical pain along with multiple episodes of vomiting and chronic constipation. An abdominal CT scan revealed an ileo-ileal intussusception of an endoluminal hypodense lesion with mesenteric lymphadenopathy. Surgical treatment consisted of segmental ileal resection with primary anastomosis. The histopathological analysis revealed an inflammatory fibroid polyp in the ileum. Although these tumors have no malignant potential, surgery is always indicated in ileo-ileal intussusception to ascertain the histological nature of the lesion.展开更多
<p style="text-align:justify;"> Early childhood development involves an appropriate global intervention concerning the different areas of development such as: physical, cognitive, language and socio-em...<p style="text-align:justify;"> Early childhood development involves an appropriate global intervention concerning the different areas of development such as: physical, cognitive, language and socio-emotional <span style="white-space:nowrap;"><a href="#ref1">[1]</a></span><span>. Especially during the first six years of life in an adequate environment rich in exchange and inter</span><span>action. We will present in this article a review of the literature concerning normal early childhood development, focus firstly in normal development’s steps, the importance of first experiences and first aid with a stable and caring attachment figure. second, we will describe the various developmental disorders, occurring during this age group which extends from birth to 6 years and based on the DSM5 classification, namely that developmental delay may concern only one aspect of development (e.g. language delay or motor delay specifically) or concern the different aspects of development (overall development delay). The dynamics of development is also important to clarify because schematically we contrast the pathologies fixed to progressive pathologies (where we find the concepts of stagnation or regression in the development of the child). We will discuss in the third chapter, the interest of early detection as well as the multiple clinical and psychometric diagnostic tools, which aim to detect any delay or disorder in order to initiate appropriate care and minimize the long-term consequences.</span> </p>展开更多
In this study, the electrochemical corrosion behavior of copper was investigated in seawater collected from four different marine zones of Agadir coastal. These zones are different by the degree of pollution in order ...In this study, the electrochemical corrosion behavior of copper was investigated in seawater collected from four different marine zones of Agadir coastal. These zones are different by the degree of pollution in order to study the effect of this pollution on the copper corrosion, especially the microbial pollution by sulfate reducing-bacteria (SRB). So, to prove this relationship, the microbiological analyses researching the SRB are realized. In parallel, the electrochemical impedance measurement and atomic absorption analysis are established to compare the microbiological evolution cycles with the electrochemical behavior of copper during the immersion period. In the results, we found a good correlation between the growth cycle of marine sulfate-reducing bacteria and the copper corrosion rate by the sulfur and extracellular polymeric substances (EPS) produced as bacteria metabolites. Additionally, this corrosion rate depends on the immersed time: it is maximal after the first or second month depending on the marine zone.展开更多
This work aims to study the phenomenon of scaling observed in the hot water pipelines in the southern seaside touristic installations of Agadir city. This phenomenon has led to the formation of solid deposits and adhe...This work aims to study the phenomenon of scaling observed in the hot water pipelines in the southern seaside touristic installations of Agadir city. This phenomenon has led to the formation of solid deposits and adherents to the internal walls of the facilities of the hot water. This deposit is at the origin of several technical, economic and environmental problems. It causes a decrease in the lifetime of boilers and a reduction of thermal exchanges and consequently a decrease in the energy efficiency of heating systems. In the present study, the samples of scale have been carried out at different points of hot water pipelines. The characterization of different scale samples recovered was conducted by X-ray fluorescence (XRF), elemental analysis (CHNS-O), infrared spectrometry (IR), thermogravimetric analysis (TGA), differential thermal analysis (DTA), X-ray diffraction (XRD) and scanning electron microscopy (SEM). Analytical results showed that scale samples collected on different sites in touristic hot water system are mostly formed by calcium carbonate. Thermodynamic conditions in the site were favourable to the aragonite variety formation.展开更多
Medulloblastoma (MB) is a malignant brain tumor with a usual potential for leptomeningeal spread. Intramedullary metastases of MB are rare and there are very few cases reported in the literature. Here, we report the c...Medulloblastoma (MB) is a malignant brain tumor with a usual potential for leptomeningeal spread. Intramedullary metastases of MB are rare and there are very few cases reported in the literature. Here, we report the case of an 18-year-old man with intramedullary spinal cord metastasis of MB occurring 9 years after the first diagnosis. The patient presented a 2-month history of progressive weakness in both lower limbs associated with urinary incontinence. Magnetic resonance imaging (MRI) demonstrated a large intramedullary spinal cord tumor extending from T10 to L1. The patient underwent surgical decompression and adjuvant therapy. Histological examination confirmed the diagnosis of classic MB metastasis. Postoperatively, the neurological status was stationary. Intramedullary metastasis of medulloblastoma is rare and difficult to manage with a poor prognosis. Comprehensive studies on the medulloblastoma dissemination mechanisms and clinical trials are needed to assess combined therapeutic approaches on metastases of MB.展开更多
Introduction: Schizophrenia and bipolar I disorder are very common disorders in hospitalized patients. Considering that family problems are one of the factors in the appearance and persistence of schizophrenia and bip...Introduction: Schizophrenia and bipolar I disorder are very common disorders in hospitalized patients. Considering that family problems are one of the factors in the appearance and persistence of schizophrenia and bipolar I disorder, in this study, we decided to investigate and compare the family functioning between these two groups of patients. Methods: The sample consisted of 50 patients with schizophrenia and 50 patients with bipolar I disorder. The third group was the control group which consisted of 50 normal different professions such as teachers, workers, housekeepers and others. Then the Family Functioning Scale (FAD-I) was used and the final results of the three groups were compared by SPSS V21 software. Results: In the schizophrenia group, 88.9% percent of patients had family functioning scores less than 109.81 which showed that they had severe family dysfunction but in the bipolar I disorder group, 11.1% and all participants in the control group, had scores higher than 109.81.Conclusion: Family dysfunction was seen in schizophrenic patients rather than in the other two groups.展开更多
The Maximum Power Point Tracker (MPPT) is the optimum operating point of a photovoltaic module. It plays a very important role to obtain the maximum power of a solar panel as it allows an optimal use of a photovoltaic...The Maximum Power Point Tracker (MPPT) is the optimum operating point of a photovoltaic module. It plays a very important role to obtain the maximum power of a solar panel as it allows an optimal use of a photovoltaic system, regardless of irradiation and temperature variations. In this research, we present a novel technique to improve the control’s performances optimization of the system consisting of a photovoltaic panel, a buck converter and a load. Simulations of different parts of the system are developed under Matlab/Simulink, thus allowing a comparison between the performances of the three studied controllers: “Fuzzy TS”, “P&O” and “PSO”. The three algorithms of MPPT associated with these techniques are tested in different meteorological conditions. The obtained results, in different operating conditions, reveal a clear improvement of controlling performances of MPPT of a photovoltaic system when the PSO tracking technique is used.展开更多
Objectives: in case of Polycystic Ovary Syndrome (SOPK), predicting ovarian response before undertaking risky in vitro fertilization (IVF) proceeds is crucial. Sex Hormone Binding Globulin (SHBG) is introduced in lite...Objectives: in case of Polycystic Ovary Syndrome (SOPK), predicting ovarian response before undertaking risky in vitro fertilization (IVF) proceeds is crucial. Sex Hormone Binding Globulin (SHBG) is introduced in literature as an interesting indicator of follicle’s maturation and quality. The aim of this study was to investigate whether serum SHBG levels are related to fertilization outcomes in SOPK women undergoing IVF procedures. Methods: in a prospective cohort study, we enrolled 61 SOPK women and 91 matched group of infertile women. All of them were undergoing FIV/ICSI proceeds. SHBG levels were performed in peripheral blood samples as well as others hormones determination. Results: we noted significant differences between our study group of SOPK patients and the Control group concerning the characteristics of the ovarian response to gonadotrophins administration and concerning the profile of biological proceeds’ outcomes. But no significant correlation between SHBG and FIV/ICSI outcomes was found either in SOPK or in Control group. Conclusions: our study provides evidence that SHBG can’t be considered as a predictor of IVF outcomes because production of this steroid-binding protein depends on many parameters such as metabolic disorders frequently associated with SOPK.展开更多
Amorphous hydrogenated silicon nitride thin films a-SiN<sub>x</sub>:H (abbreviated later by SiN<sub>x</sub>) were deposited by Electron Cyclotron Resonance plasma enhanced chemical vapor deposi...Amorphous hydrogenated silicon nitride thin films a-SiN<sub>x</sub>:H (abbreviated later by SiN<sub>x</sub>) were deposited by Electron Cyclotron Resonance plasma enhanced chemical vapor deposition method (ECR-PECVD). By changing ratio of gas flow (R = NH<sub>3</sub>/SiH<sub>4</sub>) in the reactor chamber different stoichiometric layers x = [N]/[Si] ([N] and [Si] atomic concentrations) are successfully deposited. Part of the obtained films has subsequently undergone rapid thermal annealing RTA (800°C/1 s) using halogen lamps. Optical and structural characterizations are then achieved by spectroscopic ellipsometry (SE), ion beam analysis and infrared absorption techniques. The SE measurements show that the tuning character of their refractive index n(λ) with stoichiometry x and their non-absorption properties in the range of 250 - 850 nm expect for Si-rich SiN<sub>x</sub> films in the ultraviolet UV range. The stoichiometry x and its depth profile are determined by Rutherford backscattering spectrometry (RBS) while the hydrogen profile (atomic concentration) is determined by Elastic Recoil Detection Analysis (ERDA). Vibrational characteristics of the Si-N, Si-H and N-H chemical bonds in the silicon nitride matrix are investigated by infrared absorption. An atomic hydrogen fraction ranging from 12% to 22% uniformly distributed as evaluated by ERDA is depending inversely on the stoichiometry x ranging from 0.34 to 1.46 as evaluated by RBS for the studied SiN<sub>x</sub> films. The hydrogen loss after RTA process and its out-diffusion depend strongly on the chemical structure of the films and less on the initial hydrogen concentration. A large hydrogen loss was noted for non-thermally stable Si-rich SiNx films. Rich nitrogen films are less sensitive to rapid thermal process.展开更多
Hypomagnesemia with secondary hypocalcemia (HSH) is a rare inherited disorder, characterized by extremely low levels of serum magesium associated with symptomatic hypocalcemia. HSH manifests in the new born period wit...Hypomagnesemia with secondary hypocalcemia (HSH) is a rare inherited disorder, characterized by extremely low levels of serum magesium associated with symptomatic hypocalcemia. HSH manifests in the new born period with neurological symptoms, including generalized seizures, which are refractory to anticonvulsant treatment. In this disorder, the basic abnormality is the defective intestinal absorption of magnesium. Mutations in TRPM6, the gene encoding the transient receptor potential cation channel subfamily member 6 have been found to be responsible for this disease. We report on a four-month-old Tunisian girl who presented with convulsions. Laboratory evaluation yielded extremely low serum magnesium levels, low calcium levels, and abnormal PTH levels. The diagnosis of HSH was confirmed by mutation analysis which identified the novel mutation c.1307A >G in exon 11 of TRPM6 (Lys436Arg). Our patient was homozygous for this mutation. Prenatal diagnosis was done during second pregnancy. DNA from trophoblast biopsy showed the same mutation as the proband.展开更多
Objective: The aim of this study is to determine changes in maternal serum leptin level during pregnancy and after labor in preeclamptic patients compared to healthy pregnant women. Furthermore, to investigate whether...Objective: The aim of this study is to determine changes in maternal serum leptin level during pregnancy and after labor in preeclamptic patients compared to healthy pregnant women. Furthermore, to investigate whether maternal serum leptin levels are correlated to the clinical characteristics and laboratory parameters of the study participants, and the possible correlation between maternal and neonatal leptin levels. Subjects and Methods: In this case control study, a total number of fifty five pregnant women in third trimester of pregnancy (≥28 weeks) were recruited. All of them were of the same age, body mass index, and gestational age. After a detailed obstetrical and medical history, they were divided into 2 groups. Group (A) 30 pregnant women with preeclampsia, and Group (B) 25 normotensive pregnant women. Results: During pregnancy, maternal serum leptin levels were significantly higher 41.0 ± 9.78 ng/ml in preeclamptic group compared to control group 24.6 ± 3.64 ng/ml (p = 0.007). After labor, it decreased significantly in both groups to 15.3 ± 3.19, and 11.2 ± 2.68 ng/ml respectively (p = 0.001, 0.002). In group (A) there were significant positive correlations between maternal serum leptin and diastolic blood pressure (r = 0.419, p = 0.021), total cholesterol (r = 0.383, p = 0.026), and uric acid (r = 0.424, p = 0.012) compared to controls, and no significant correlations were found between maternal serum leptin and body mass index, neonatal birth weight or cord leptin level in both groups. Conclusion: Maternal serum leptin is significantly increased in preeclamptic patients compared with normal pregnant women independent of body mass index. There is strong evidence that placenta, rather than maternal adipose tissue is responsible for that. In addition, maternal serum leptin levels were found to correlate positively with diastolic blood pressure, uric acid, and total cholesterol, but not correlated with body mass index, cord blood leptin and birth weight.展开更多
Background: Cardiovascular diseases (CVDs) are the leading cause of death globally. An estimated 17.9 million people died from CVDs in 2019, representing 32% of all global deaths. Of these deaths, 85% were due to hear...Background: Cardiovascular diseases (CVDs) are the leading cause of death globally. An estimated 17.9 million people died from CVDs in 2019, representing 32% of all global deaths. Of these deaths, 85% were due to heart attack and stroke. Over three quarters of CVD deaths take place in low- and middle-income countries. We have studied the pattern of mortality due to cardiovascular in the six countries of the Arabian Gulf and its association with obesity over the 29 years 1990 to 2019. Methods: We used the linear mixed effect models to investigate the pattern of CVD mortality over the year 1990 to 2019, together with the pattern of change in one of the most important risk factors that is obesity, and its association with CVD mortality over the same period. Conclusions: Although there were fluctuations in the pattern of mortality and the prevalence of obesity over the specified period, there has been a steady decline in the per-100,000 number of deaths and the prevalence of obesity. However, there was a strong association between the two variables. From the fitted models we estimated that a one percent increase in obesity is associated with an average increase in cardiovascular deaths of 2.7 deaths per 100,000.展开更多
Background: The emergence of carbapenemase producing Acinetobacter baumannii is increasingly reported nowadays and constitutes a major problem to the intensive care unit (ICU) patients with notable extensive-drug resi...Background: The emergence of carbapenemase producing Acinetobacter baumannii is increasingly reported nowadays and constitutes a major problem to the intensive care unit (ICU) patients with notable extensive-drug resistance ability. The study investigates carbapenemase producing A. baumannii strains exhibiting an extensively drug-resistant (XDR) phenotype, isolated from ICU patients in Khartoum. Methods: A total of 100 nonduplicate Gram-negative coccobacilli strains were obtained from microbiology laboratory of ICU patients’ clinical isolates. Molecular identification of A. baumannii was performed by targeting 16S rRNA gene using specifically designed primers. Then, XDR strains were determined by susceptibility testing (disc diffusion). For detection of carbapenemase genes Polymerase chain reaction (PCR) was carried out. Result: Of 100 ICU clinical isolates, 38 (38.0%) was confirmed A. baumannii strains, those strains showed 100% carbapenem resistance and 60.5% extensive drug resistance to the antibiotics tested. The frequency of carbapenemase producer was 57.9% (22/38) of carbapenem resistance A. baumannii (CRAB). The most common carbapenemase associated with resistance was blaOXA gene followed by blaNDM and blaGES A. baumannii isolates. The co-occurrence of blaOXA-48-like and blaNDM, blaOXA-23-like and blaOXA-51, and blaNDM-1 and blaOXA-51 was detected in 22.7%, 18.2% strains and 4.5% respectively. A unique characteristic of our findings was the coharbouring of the genes blaNDM-1, blaOXA-23-like, blaOXA-51 and blaOXA-143 in 9.1% strains (2/22), and this was the first report in the Khartoum city, Sudan. Conclusion: We have demonstrated for the first time a high prevalence of XDR-carbapenemase producing A. baumannii clinical isolates from ICU patients in Khartoum. Also an emergent blaOXA-143 was reported as High-Risk Clones. This highlights the routine mentoring of XDR-carbapenemase producing A. baumannii to avoid clone dissemination in our region hospitals.展开更多
In the treatment of OCD, several therapeutic approaches have been developed, including individual, group and/or pharmacological therapeutic methods. However, group therapy on OCD has received little research attention...In the treatment of OCD, several therapeutic approaches have been developed, including individual, group and/or pharmacological therapeutic methods. However, group therapy on OCD has received little research attention in comparison with other therapeutic methods and some studies demonstrated that OCD can be treated in group settings. In the literature, mentioned group therapies to treat OCD involve behavioral therapy, cognitive therapy, ERP (exposure and response prevention), cognitive behavioral therapy, ACT (acceptance and commitment therapy), supportive groups and individual therapy with family member involvement. In relation to their effectiveness, research indicated inconsistent findings. Therefore, the aim of this study was to address and to review whether group treatments on OCD are efficacious. This review focused on cognitive-behavioral group therapy (CBGT), ERP, and ACT.展开更多
文摘Sirenomelia is a rare and lethal condition and its etiopathogenesis is unclear. The diagnosis is based on first trimester ultrasound showing a complete fusion of soft tissue in both lower limbs and other visceral abnormalities. We report in this article, the misdiagnose of sirenomelia as IUGR leading the other to continue the pregnancy until 35 weeks of gestation.
文摘Duchenne muscular dystrophy (DMD) is a hereditary, progressive muscular disorder inherited in an X-linked recessive pattern (Xp21). It typically manifests in childhood and follows a severe, rapid progression. Only males are affected, while females are usually carriers. Given the genetic nature of DMD, genetic counseling is an essential service for individuals affected by or at risk of carrying the disease. This service provides not only crucial medical information but also psychosocial support and ongoing management for both patients and their families. Since the discovery of the dystrophin gene in 1987, advancements in molecular genetics have made it possible to precisely identify the genes responsible for many neuromuscular diseases. These developments have revolutionized diagnosis, prognosis, and most importantly, genetic counseling, offering significant benefits for both patients and their families. To highlight the significance of these advancements, this case report focuses on a 10-year-old boy (Y) diagnosed with DMD. It emphasizes the familial nature of the disease, with Y’s two brothers, three cousins, and two maternal uncles also affected, underscoring the inherited pattern of DMD. This reinforces the critical need for early intervention, particularly in regions with high consanguinity, such as North Africa and the Middle East, where genetic counseling and prenatal diagnosis are even more essential. Additionally, the report explores the clinical presentation, diagnostic findings, and promising emerging treatments, including RNA-based therapies, which may play a key role in the future management of DMD. In light of the above, this study underscores the importance of prenatal diagnosis and genetic counseling, particularly in regions like Morocco, where consanguinity rates are notably high. By focusing on preconception care and early genetic intervention, families can be better informed, leading to more effective disease management and support.
文摘Obesity is a significant global health concern, often leading to comorbidities such as cardiovascular diseases, diabetes, and hypertension. Bariatric surgery, including sleeve gastrectomy (SG), is a proven treatment for morbid obesity, offering substantial weight loss and resolution of comorbidities. However, post-surgical complications, particularly anorectal disorders such as hemorrhoids and anal fissures, remain underexplored, especially in Saudi Arabia. This retrospective cohort study aimed to assess the prevalence, risk factors, and impact of anal complications following SG at Almoosa Specialist Hospital in Alhassa, Saudi Arabia. A total of 205 patients who underwent SG between January 2020 and December 2021 were surveyed, with 148 eligible participants included in the final analysis. Results indicated that 8.8% of patients experienced anal complications, with anal fissures (53.8%) and hemorrhoids (38.5%) being the most common. These complications typically occurred 2 - 6 months post-surgery. Lifestyle factors such as physical activity and fluid intake were found to significantly reduce the likelihood of anal issues. Moreover, 69.2% of patients with anal problems reported a negative impact on their quality of life. The study highlights the importance of targeted post-operative care, including lifestyle modifications, to mitigate the impact of anal complications. The findings suggest that ongoing education and comprehensive support for bariatric surgery patients, particularly regarding physical activity and hydration, are critical for improving long-term health outcomes. Further research is needed to explore the long-term progression of anal complications and effective interventions for enhancing patient satisfaction and quality of life.
文摘In 2012, Ponraj et al. defined a concept of k-product cordial labeling as follows: Let f be a map from V(G)to { 0,1,⋯,k−1 }where k is an integer, 1≤k≤| V(G) |. For each edge uvassign the label f(u)f(v)(modk). f is called a k-product cordial labeling if | vf(i)−vf(j) |≤1, and | ef(i)−ef(j) |≤1, i,j∈{ 0,1,⋯,k−1 }, where vf(x)and ef(x)denote the number of vertices and edges respectively labeled with x (x=0,1,⋯,k−1). Motivated by this concept, we further studied and established that several families of graphs admit k-product cordial labeling. In this paper, we show that the path graphs Pnadmit k-product cordial labeling.
文摘Inflammatory fibroid polyps (IFP) are a rare benign entity that arises from the submucosa of the gastrointestinal tract and protrudes into the lumen. The clinical presentation depends on the size and localization. They are particularly found in the ileum, where they are frequently present as an ileal intussusception. We report the case of a 56-year-old female patient who presented with periumbilical pain along with multiple episodes of vomiting and chronic constipation. An abdominal CT scan revealed an ileo-ileal intussusception of an endoluminal hypodense lesion with mesenteric lymphadenopathy. Surgical treatment consisted of segmental ileal resection with primary anastomosis. The histopathological analysis revealed an inflammatory fibroid polyp in the ileum. Although these tumors have no malignant potential, surgery is always indicated in ileo-ileal intussusception to ascertain the histological nature of the lesion.
文摘<p style="text-align:justify;"> Early childhood development involves an appropriate global intervention concerning the different areas of development such as: physical, cognitive, language and socio-emotional <span style="white-space:nowrap;"><a href="#ref1">[1]</a></span><span>. Especially during the first six years of life in an adequate environment rich in exchange and inter</span><span>action. We will present in this article a review of the literature concerning normal early childhood development, focus firstly in normal development’s steps, the importance of first experiences and first aid with a stable and caring attachment figure. second, we will describe the various developmental disorders, occurring during this age group which extends from birth to 6 years and based on the DSM5 classification, namely that developmental delay may concern only one aspect of development (e.g. language delay or motor delay specifically) or concern the different aspects of development (overall development delay). The dynamics of development is also important to clarify because schematically we contrast the pathologies fixed to progressive pathologies (where we find the concepts of stagnation or regression in the development of the child). We will discuss in the third chapter, the interest of early detection as well as the multiple clinical and psychometric diagnostic tools, which aim to detect any delay or disorder in order to initiate appropriate care and minimize the long-term consequences.</span> </p>
文摘In this study, the electrochemical corrosion behavior of copper was investigated in seawater collected from four different marine zones of Agadir coastal. These zones are different by the degree of pollution in order to study the effect of this pollution on the copper corrosion, especially the microbial pollution by sulfate reducing-bacteria (SRB). So, to prove this relationship, the microbiological analyses researching the SRB are realized. In parallel, the electrochemical impedance measurement and atomic absorption analysis are established to compare the microbiological evolution cycles with the electrochemical behavior of copper during the immersion period. In the results, we found a good correlation between the growth cycle of marine sulfate-reducing bacteria and the copper corrosion rate by the sulfur and extracellular polymeric substances (EPS) produced as bacteria metabolites. Additionally, this corrosion rate depends on the immersed time: it is maximal after the first or second month depending on the marine zone.
文摘This work aims to study the phenomenon of scaling observed in the hot water pipelines in the southern seaside touristic installations of Agadir city. This phenomenon has led to the formation of solid deposits and adherents to the internal walls of the facilities of the hot water. This deposit is at the origin of several technical, economic and environmental problems. It causes a decrease in the lifetime of boilers and a reduction of thermal exchanges and consequently a decrease in the energy efficiency of heating systems. In the present study, the samples of scale have been carried out at different points of hot water pipelines. The characterization of different scale samples recovered was conducted by X-ray fluorescence (XRF), elemental analysis (CHNS-O), infrared spectrometry (IR), thermogravimetric analysis (TGA), differential thermal analysis (DTA), X-ray diffraction (XRD) and scanning electron microscopy (SEM). Analytical results showed that scale samples collected on different sites in touristic hot water system are mostly formed by calcium carbonate. Thermodynamic conditions in the site were favourable to the aragonite variety formation.
文摘Medulloblastoma (MB) is a malignant brain tumor with a usual potential for leptomeningeal spread. Intramedullary metastases of MB are rare and there are very few cases reported in the literature. Here, we report the case of an 18-year-old man with intramedullary spinal cord metastasis of MB occurring 9 years after the first diagnosis. The patient presented a 2-month history of progressive weakness in both lower limbs associated with urinary incontinence. Magnetic resonance imaging (MRI) demonstrated a large intramedullary spinal cord tumor extending from T10 to L1. The patient underwent surgical decompression and adjuvant therapy. Histological examination confirmed the diagnosis of classic MB metastasis. Postoperatively, the neurological status was stationary. Intramedullary metastasis of medulloblastoma is rare and difficult to manage with a poor prognosis. Comprehensive studies on the medulloblastoma dissemination mechanisms and clinical trials are needed to assess combined therapeutic approaches on metastases of MB.
文摘Introduction: Schizophrenia and bipolar I disorder are very common disorders in hospitalized patients. Considering that family problems are one of the factors in the appearance and persistence of schizophrenia and bipolar I disorder, in this study, we decided to investigate and compare the family functioning between these two groups of patients. Methods: The sample consisted of 50 patients with schizophrenia and 50 patients with bipolar I disorder. The third group was the control group which consisted of 50 normal different professions such as teachers, workers, housekeepers and others. Then the Family Functioning Scale (FAD-I) was used and the final results of the three groups were compared by SPSS V21 software. Results: In the schizophrenia group, 88.9% percent of patients had family functioning scores less than 109.81 which showed that they had severe family dysfunction but in the bipolar I disorder group, 11.1% and all participants in the control group, had scores higher than 109.81.Conclusion: Family dysfunction was seen in schizophrenic patients rather than in the other two groups.
文摘The Maximum Power Point Tracker (MPPT) is the optimum operating point of a photovoltaic module. It plays a very important role to obtain the maximum power of a solar panel as it allows an optimal use of a photovoltaic system, regardless of irradiation and temperature variations. In this research, we present a novel technique to improve the control’s performances optimization of the system consisting of a photovoltaic panel, a buck converter and a load. Simulations of different parts of the system are developed under Matlab/Simulink, thus allowing a comparison between the performances of the three studied controllers: “Fuzzy TS”, “P&O” and “PSO”. The three algorithms of MPPT associated with these techniques are tested in different meteorological conditions. The obtained results, in different operating conditions, reveal a clear improvement of controlling performances of MPPT of a photovoltaic system when the PSO tracking technique is used.
文摘Objectives: in case of Polycystic Ovary Syndrome (SOPK), predicting ovarian response before undertaking risky in vitro fertilization (IVF) proceeds is crucial. Sex Hormone Binding Globulin (SHBG) is introduced in literature as an interesting indicator of follicle’s maturation and quality. The aim of this study was to investigate whether serum SHBG levels are related to fertilization outcomes in SOPK women undergoing IVF procedures. Methods: in a prospective cohort study, we enrolled 61 SOPK women and 91 matched group of infertile women. All of them were undergoing FIV/ICSI proceeds. SHBG levels were performed in peripheral blood samples as well as others hormones determination. Results: we noted significant differences between our study group of SOPK patients and the Control group concerning the characteristics of the ovarian response to gonadotrophins administration and concerning the profile of biological proceeds’ outcomes. But no significant correlation between SHBG and FIV/ICSI outcomes was found either in SOPK or in Control group. Conclusions: our study provides evidence that SHBG can’t be considered as a predictor of IVF outcomes because production of this steroid-binding protein depends on many parameters such as metabolic disorders frequently associated with SOPK.
文摘Amorphous hydrogenated silicon nitride thin films a-SiN<sub>x</sub>:H (abbreviated later by SiN<sub>x</sub>) were deposited by Electron Cyclotron Resonance plasma enhanced chemical vapor deposition method (ECR-PECVD). By changing ratio of gas flow (R = NH<sub>3</sub>/SiH<sub>4</sub>) in the reactor chamber different stoichiometric layers x = [N]/[Si] ([N] and [Si] atomic concentrations) are successfully deposited. Part of the obtained films has subsequently undergone rapid thermal annealing RTA (800°C/1 s) using halogen lamps. Optical and structural characterizations are then achieved by spectroscopic ellipsometry (SE), ion beam analysis and infrared absorption techniques. The SE measurements show that the tuning character of their refractive index n(λ) with stoichiometry x and their non-absorption properties in the range of 250 - 850 nm expect for Si-rich SiN<sub>x</sub> films in the ultraviolet UV range. The stoichiometry x and its depth profile are determined by Rutherford backscattering spectrometry (RBS) while the hydrogen profile (atomic concentration) is determined by Elastic Recoil Detection Analysis (ERDA). Vibrational characteristics of the Si-N, Si-H and N-H chemical bonds in the silicon nitride matrix are investigated by infrared absorption. An atomic hydrogen fraction ranging from 12% to 22% uniformly distributed as evaluated by ERDA is depending inversely on the stoichiometry x ranging from 0.34 to 1.46 as evaluated by RBS for the studied SiN<sub>x</sub> films. The hydrogen loss after RTA process and its out-diffusion depend strongly on the chemical structure of the films and less on the initial hydrogen concentration. A large hydrogen loss was noted for non-thermally stable Si-rich SiNx films. Rich nitrogen films are less sensitive to rapid thermal process.
文摘Hypomagnesemia with secondary hypocalcemia (HSH) is a rare inherited disorder, characterized by extremely low levels of serum magesium associated with symptomatic hypocalcemia. HSH manifests in the new born period with neurological symptoms, including generalized seizures, which are refractory to anticonvulsant treatment. In this disorder, the basic abnormality is the defective intestinal absorption of magnesium. Mutations in TRPM6, the gene encoding the transient receptor potential cation channel subfamily member 6 have been found to be responsible for this disease. We report on a four-month-old Tunisian girl who presented with convulsions. Laboratory evaluation yielded extremely low serum magnesium levels, low calcium levels, and abnormal PTH levels. The diagnosis of HSH was confirmed by mutation analysis which identified the novel mutation c.1307A >G in exon 11 of TRPM6 (Lys436Arg). Our patient was homozygous for this mutation. Prenatal diagnosis was done during second pregnancy. DNA from trophoblast biopsy showed the same mutation as the proband.
文摘Objective: The aim of this study is to determine changes in maternal serum leptin level during pregnancy and after labor in preeclamptic patients compared to healthy pregnant women. Furthermore, to investigate whether maternal serum leptin levels are correlated to the clinical characteristics and laboratory parameters of the study participants, and the possible correlation between maternal and neonatal leptin levels. Subjects and Methods: In this case control study, a total number of fifty five pregnant women in third trimester of pregnancy (≥28 weeks) were recruited. All of them were of the same age, body mass index, and gestational age. After a detailed obstetrical and medical history, they were divided into 2 groups. Group (A) 30 pregnant women with preeclampsia, and Group (B) 25 normotensive pregnant women. Results: During pregnancy, maternal serum leptin levels were significantly higher 41.0 ± 9.78 ng/ml in preeclamptic group compared to control group 24.6 ± 3.64 ng/ml (p = 0.007). After labor, it decreased significantly in both groups to 15.3 ± 3.19, and 11.2 ± 2.68 ng/ml respectively (p = 0.001, 0.002). In group (A) there were significant positive correlations between maternal serum leptin and diastolic blood pressure (r = 0.419, p = 0.021), total cholesterol (r = 0.383, p = 0.026), and uric acid (r = 0.424, p = 0.012) compared to controls, and no significant correlations were found between maternal serum leptin and body mass index, neonatal birth weight or cord leptin level in both groups. Conclusion: Maternal serum leptin is significantly increased in preeclamptic patients compared with normal pregnant women independent of body mass index. There is strong evidence that placenta, rather than maternal adipose tissue is responsible for that. In addition, maternal serum leptin levels were found to correlate positively with diastolic blood pressure, uric acid, and total cholesterol, but not correlated with body mass index, cord blood leptin and birth weight.
文摘Background: Cardiovascular diseases (CVDs) are the leading cause of death globally. An estimated 17.9 million people died from CVDs in 2019, representing 32% of all global deaths. Of these deaths, 85% were due to heart attack and stroke. Over three quarters of CVD deaths take place in low- and middle-income countries. We have studied the pattern of mortality due to cardiovascular in the six countries of the Arabian Gulf and its association with obesity over the 29 years 1990 to 2019. Methods: We used the linear mixed effect models to investigate the pattern of CVD mortality over the year 1990 to 2019, together with the pattern of change in one of the most important risk factors that is obesity, and its association with CVD mortality over the same period. Conclusions: Although there were fluctuations in the pattern of mortality and the prevalence of obesity over the specified period, there has been a steady decline in the per-100,000 number of deaths and the prevalence of obesity. However, there was a strong association between the two variables. From the fitted models we estimated that a one percent increase in obesity is associated with an average increase in cardiovascular deaths of 2.7 deaths per 100,000.
文摘Background: The emergence of carbapenemase producing Acinetobacter baumannii is increasingly reported nowadays and constitutes a major problem to the intensive care unit (ICU) patients with notable extensive-drug resistance ability. The study investigates carbapenemase producing A. baumannii strains exhibiting an extensively drug-resistant (XDR) phenotype, isolated from ICU patients in Khartoum. Methods: A total of 100 nonduplicate Gram-negative coccobacilli strains were obtained from microbiology laboratory of ICU patients’ clinical isolates. Molecular identification of A. baumannii was performed by targeting 16S rRNA gene using specifically designed primers. Then, XDR strains were determined by susceptibility testing (disc diffusion). For detection of carbapenemase genes Polymerase chain reaction (PCR) was carried out. Result: Of 100 ICU clinical isolates, 38 (38.0%) was confirmed A. baumannii strains, those strains showed 100% carbapenem resistance and 60.5% extensive drug resistance to the antibiotics tested. The frequency of carbapenemase producer was 57.9% (22/38) of carbapenem resistance A. baumannii (CRAB). The most common carbapenemase associated with resistance was blaOXA gene followed by blaNDM and blaGES A. baumannii isolates. The co-occurrence of blaOXA-48-like and blaNDM, blaOXA-23-like and blaOXA-51, and blaNDM-1 and blaOXA-51 was detected in 22.7%, 18.2% strains and 4.5% respectively. A unique characteristic of our findings was the coharbouring of the genes blaNDM-1, blaOXA-23-like, blaOXA-51 and blaOXA-143 in 9.1% strains (2/22), and this was the first report in the Khartoum city, Sudan. Conclusion: We have demonstrated for the first time a high prevalence of XDR-carbapenemase producing A. baumannii clinical isolates from ICU patients in Khartoum. Also an emergent blaOXA-143 was reported as High-Risk Clones. This highlights the routine mentoring of XDR-carbapenemase producing A. baumannii to avoid clone dissemination in our region hospitals.
文摘In the treatment of OCD, several therapeutic approaches have been developed, including individual, group and/or pharmacological therapeutic methods. However, group therapy on OCD has received little research attention in comparison with other therapeutic methods and some studies demonstrated that OCD can be treated in group settings. In the literature, mentioned group therapies to treat OCD involve behavioral therapy, cognitive therapy, ERP (exposure and response prevention), cognitive behavioral therapy, ACT (acceptance and commitment therapy), supportive groups and individual therapy with family member involvement. In relation to their effectiveness, research indicated inconsistent findings. Therefore, the aim of this study was to address and to review whether group treatments on OCD are efficacious. This review focused on cognitive-behavioral group therapy (CBGT), ERP, and ACT.
