Throughout history,cultural norms and stereotypes have discouraged resistance training in women.Today,as awareness and acceptance of resistance training in women has grown,supported by scientific research and advocacy...Throughout history,cultural norms and stereotypes have discouraged resistance training in women.Today,as awareness and acceptance of resistance training in women has grown,supported by scientific research and advocacy,more women are achieving health and performance benefits from resistance training.This narrative review discusses the current scientific literature on sexual dimorphisms,the mechanisms underlying health and performance adaptations of resistance training in women,with implications for program design.In general,the physiological adaptations to resistance training in women are mediated largely by the neuroendocrine and immune systems,similar to in men albeit via some distinct predominant pathways involving sex hormones estrogen,testosterone,growth hormone(GH),and insulin-like growth factor-I(IGF-I).As a result,women may have unique adaptations in terms of muscle hypertrophy,substrate utilization,fatiguability,and recovery.Despite subtle physiological differences,women achieve measurable increases in strength,power and athletic performance via engaging in resistance training programs of sufficient frequency,intensity,and duration.Moreover,beyond performance,resistance training has a favorable impact on women’s health including metabolic health,body composition,bone health,cardiovascular health,mental health,self-esteem,and body image.Resistance training recommendations for men and women are highly similar and goal-dependent,with some specific caveats that need to be addressed in women.As resistance training has become regarded as a key element of programs for achieving performance and health improvements in women,additional research may further our understanding.展开更多
Urinary tract infections (UTIs) are among the most common maladies afflicting the human population globally. A wide variety of microbial pathogens are responsible for causing UTIs that are often recurrent, especially ...Urinary tract infections (UTIs) are among the most common maladies afflicting the human population globally. A wide variety of microbial pathogens are responsible for causing UTIs that are often recurrent, especially in the elderly population, resulting in an economic burden of billions of dollars annually. In this study, we present data from a large population of symptomatic UTI patients tested using a multiplexed, real time quantitative polymerase chain reaction (qRT-PCR) strategy. Our data demonstrate that instances of UTI increase with age for all the tested pathogens, with the exception of Mycoplasma spp. and Ureaplasma spp., which were found to be significantly higher in the younger population. Furthermore, the use of the qRT-PCR approach was also found to be effective in detecting polymicrobial UTIs. With the limitations of classical microbial culture techniques traditionally used for UTI diagnosis, we demonstrate that a rapid and comprehensive technique like RT-PCR can be an effective tool for detecting and managing UTIs.展开更多
文摘Throughout history,cultural norms and stereotypes have discouraged resistance training in women.Today,as awareness and acceptance of resistance training in women has grown,supported by scientific research and advocacy,more women are achieving health and performance benefits from resistance training.This narrative review discusses the current scientific literature on sexual dimorphisms,the mechanisms underlying health and performance adaptations of resistance training in women,with implications for program design.In general,the physiological adaptations to resistance training in women are mediated largely by the neuroendocrine and immune systems,similar to in men albeit via some distinct predominant pathways involving sex hormones estrogen,testosterone,growth hormone(GH),and insulin-like growth factor-I(IGF-I).As a result,women may have unique adaptations in terms of muscle hypertrophy,substrate utilization,fatiguability,and recovery.Despite subtle physiological differences,women achieve measurable increases in strength,power and athletic performance via engaging in resistance training programs of sufficient frequency,intensity,and duration.Moreover,beyond performance,resistance training has a favorable impact on women’s health including metabolic health,body composition,bone health,cardiovascular health,mental health,self-esteem,and body image.Resistance training recommendations for men and women are highly similar and goal-dependent,with some specific caveats that need to be addressed in women.As resistance training has become regarded as a key element of programs for achieving performance and health improvements in women,additional research may further our understanding.
文摘Urinary tract infections (UTIs) are among the most common maladies afflicting the human population globally. A wide variety of microbial pathogens are responsible for causing UTIs that are often recurrent, especially in the elderly population, resulting in an economic burden of billions of dollars annually. In this study, we present data from a large population of symptomatic UTI patients tested using a multiplexed, real time quantitative polymerase chain reaction (qRT-PCR) strategy. Our data demonstrate that instances of UTI increase with age for all the tested pathogens, with the exception of Mycoplasma spp. and Ureaplasma spp., which were found to be significantly higher in the younger population. Furthermore, the use of the qRT-PCR approach was also found to be effective in detecting polymicrobial UTIs. With the limitations of classical microbial culture techniques traditionally used for UTI diagnosis, we demonstrate that a rapid and comprehensive technique like RT-PCR can be an effective tool for detecting and managing UTIs.
