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Renal vessel-assisted anastomosis improves the abdominal heart transplant model in rats without bilateral lower limb ischemia
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作者 Meng Wang Wuxia Wang Xunfeng Zou 《Animal Models and Experimental Medicine》 2026年第2期407-415,共9页
Background:The traditional method of heterotopic abdominal heart transplantation(HTx)involves crossclamping the inferior vena cava,which inevitably leads to bilateral lower limb ischemia(LI).This study first aimed to ... Background:The traditional method of heterotopic abdominal heart transplantation(HTx)involves crossclamping the inferior vena cava,which inevitably leads to bilateral lower limb ischemia(LI).This study first aimed to investigate the impact of LI on renal function in rats subjected to unilateral nephrectomy(UNx).Second,a modified method utilizing renal vessel-assisted anastomosis in rats with left UNx was compared with the traditional method for abdominal HTx.Methods:Male Sprague-Dawley rats were utilized as subjects for both experimental phases.In experiment 1,the animals were divided into four groups:sham operation group;LI group-rats undergoing occlusion of the abdominal aorta and vena cava below the renal vessels;UNx group-rats with left UNx;and LI+UNx group.All operated animals were monitored for up to 7 days for biochemical markers,renal histopathology,and survival rates.In experiment 2,we introduced the renal vessel-assisted method as the experimental group and compared it against the traditional method as the control within rat heterotopic HTx models.We assessed operative characteristics,echocardiography results,histological findings,and graft survival.Results:First,LI resulted in acute kidney dysfunction characterized by a decrease in 7day survival rates and creatinine clearance rates in both the LI and LI+UNx groups compared to the sham operation and UNx groups.Particularly,histopathological damage in the kidney and liver did not exhibit significant effects during this period.Second,the implementation of the renal vessel-assisted method significantly reduced bleeding volume at suture sites and enhanced the 7day survival rate compared to the traditional method.Conclusion:Acute kidney injury was induced by LI postoperation in treated rats.The renal vessel-assisted method demonstrated its effectiveness as a superior alternative that mitigates complications associated with the traditional method. 展开更多
关键词 animal model heart transplantation renal vessels TRANSPLANTATION vascular anastomosis
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Correlation between women's sub-health and reproductive diseases with pregnancies and labors 被引量:19
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作者 Xiaojuan Xu Qian Zeng +2 位作者 Hong Ding Lingyan Feng Linwen Deng 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2014年第4期465-469,共5页
OBJECTIVE: To investigate whether female sub-health conditions and reproductive diseases areassociated with pregnancies and labors.METHODS: A cross-sectional survey was performed by using a structured questionnaire. A... OBJECTIVE: To investigate whether female sub-health conditions and reproductive diseases areassociated with pregnancies and labors.METHODS: A cross-sectional survey was performed by using a structured questionnaire. A total of 1343 women aged 35 years or younger in six urban areas of Chengdu were included in the study.According to the Screening Criteria of sub-health conditions, these women were categorized into three groups: postpartum healthy group,sub-healthy group, and reproductive disease group. Data were double-entered using EpiData and the nanalyzed by SPSS.RESULTS: Pregnancy and labor were correlated with postpartum sub-health conditions. The number of pregnancies was negatively correlated with women's postnatal health but was positively correlated with the incidence of postpartum reproductive diseases.CONCLUSION: The number of pregnancies and labors is probably an important factor leading to sub-health conditions and the occurrence of reproductive diseases in women. Avoiding or reducing unwanted pregnancies and labors, enhancing the awareness of health among child bearing-age women are effective measures for preventing sub-health conditions. 展开更多
关键词 Sub-health Reproductive disease Pregnancy Labor Correlation Medicine Chinese traditional
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Morphometric Characteristics and Reproductive Performance of Pasundan Cattle in the North Prianganese and Southern South Coast Region
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作者 Mas Yedi Sumaryadi Euis Nia Setiawati +1 位作者 Agus Triyanto Vony Armelia 《Journal of Zoological Research》 2021年第2期9-17,共9页
This study aims to determine the morphometric characteristics and reproductive performance of Pasundan cows which are extensively reared on smallholder farms in the coastal areas of the south(Garut,Cianjur,and Sukabum... This study aims to determine the morphometric characteristics and reproductive performance of Pasundan cows which are extensively reared on smallholder farms in the coastal areas of the south(Garut,Cianjur,and Sukabumi)and North Priangan(Bogor,Purwakarta,and Sumedang).This research is descriptive research with a qualitative approach.Production characterization was carried out using a simple method,namely by measuring the body surface including shoulder height,chest circumference,body length,and bodyweight of Pasundan cattle.Meanwhile,the reproductive characteristics discuss puberty,service per conception(S/C),conception rate(CR),calving rate,postpartum estrus,postpartum mating,days open(DO),calving interval(CI),calving birth weight,calving rate,and calves weight growth.Data were collected by survey,and the location was determined by purposive sampling in the area of the seed source with the largest population and the random sampling of livestock was determined purposively as many as 30 Pasundan cows from each region.Data were analyzed using quantitative descriptive analysis.The results showed that the morphometric characteristics of Pasundan cattle included mean shoulder height of 123.00±3.06a cm VS 121.34±2.82a in males and 110.34±2.78 vs 108.00±2.14a in females.Body length 115.74±3.30 cm VS 115.34±2.97acm in males and 112.67±2.97cm VS 109.67±1.82 cm in females.Chest circumference 145.67±2.97cm VS 142.67±2.67cm bulls and 136.00±2.95cm VS 131.00±2.92cm in females,Bodyweight 268.0±17.00 kg VS 246.00±7.00a for males and 215.0±15.00 kg VS 194.00±54.00kg in females.As for reproductive characteristics,it shows puberty of 20-24 months.,S/C 1.4-1.6,Conception rate 65-70%,calving rate 62.5-65%,Postpartum Estrus 50-60 days,postpartum mating 72-104 days,day-open 94-126 days and a calving interval of 12-14 months.Calves'birth weight was 18.0-18.5 kg and daily body weight gain ranged from 0.48 to 0.50 kg.It was concluded that the morphometric characteristics and reproductive performance of Pasundan cattle in the Pesisir Selatan area were better than North Priangan. 展开更多
关键词 Pasundan cattle Morphometric characteristics Reproductive performance
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The effects of information platform-based nursing on preventing venous thromboembolism in patients with hip fractures 被引量:3
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作者 Yuan Gao Xiao-Jie Fu +4 位作者 Ming-Xing Lei Peng-Bin Yin Yu-Tong Meng Qing-Mei Wang Hong-Ying Pi 《Chinese Journal of Traumatology》 CAS CSCD 2022年第6期367-374,共8页
Purpose:Venous thromboembolism(VTE)is a major health issue among hip fracture patients.This study aimed to develop an information platform based on a mobile application and then evaluate whether information platform-b... Purpose:Venous thromboembolism(VTE)is a major health issue among hip fracture patients.This study aimed to develop an information platform based on a mobile application and then evaluate whether information platform-based nursing could improve patient’’s drug compliance and reduce the incidence of VTE in hip fracture patients.Methods:This study retrospectively analyzed hip fracture patients who were treated with conventional prevention and intervention methods for VTE(control group)between January 2008 and November 2012,and prospectively analyzed hip fracture patients who were treated with nursing intervention based on the information platform(study group)between January 2016 and September 2017.All the patients included in the both groups were hip fracture patients who had an age over 50 years,treated with surgery,and hospitalized≥48 h.Patients were excluded if they admitted to hospital due to old fractures,had a severe bleeding after 72 h of admission,diagnosed with any type of VTE,or refused to participate in the study.The information platform was divided into medical,nursing,and patient interface.Based on the information platform,medical practitioners and nurses could perform risk assessments,monitoring management and early warnings,preventions and treatments,health educations,follow-up,and other aspects of nursing interventions for patients.This study compared essential characteristics,drug compliance,VTE occurrence,and mean length of hospitalization between the two groups.Besides,a subgroup analysis was performed in the study group according to different drug compliances.SPSS 18.0 software(IBM Corp.,NY,and USA)was used for statistical analysis.Results:Altogether 1177 patients were included in the control group,and 491 patients in the study group.Regarding baseline data,patients in the study group had more morbidities than those in the control group(p<0.05).The difference of drug compliance between the two groups was statistically significant(p<0.001):761(64.7%)of the patients in the control group and only 30(6.1%)patients in the study group had poor drug compliance.In terms of VTE,10.7%patients(126/1177)in the control group had VTE,and the rate in the study group was 7.1%(35/491),showing a statistically significant difference(p=0.02).Moreover,the average length of hospitalization in the study group was also significantly lower than that in the control group(10.4 daysvs.13.7 days,p<0.001).Subgroup analyses of the study group showed that the incidence of VTE in patients with poor,partial,and good compliances were 56.7%(17/30),5.8%(10/171),and 2.8%(8/290),respectively,revealing a significantly huge difference(p<0.001).Conclusions:Poor drug compliance leads to higher VTE occurrence.The information platform-based nursing can effectively improve the compliance of hip fracture patients and thus considerably reduce the incidence of VTE.The mobile application may be an effective tool to prevent VTE in hip fracture patients. 展开更多
关键词 Venous thromboembolism Hip fractures Information platform-based nursing Drug compliance Risk assessment and management
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