Background Health promotion(HP)interventions delivered through sports clubs have demonstrated promising outcomes among men,but less is known about which aspects of the interventions work,for whom,and under what circum...Background Health promotion(HP)interventions delivered through sports clubs have demonstrated promising outcomes among men,but less is known about which aspects of the interventions work,for whom,and under what circumstances.This rapid realist review aimed to understand the contexts,mechanisms,and outcomes of HP interventions for men delivered through sports clubs.Methods A systematic literature search was conducted in February 2023 for studies published after 2013 in MEDLINE,Embase,and SPORTDiscus databases.Included studies:(a)were delivered by or in collaboration with sports clubs,(b)targeted men aged 18+years,and(c)reported 1 or more HP outcomes.A grey literature search was also performed.Studies were included in a realist synthesis based on richness and rigor.Hereafter,context-mechanism-outcome(CMO)configurations were developed.Results We identified and screened 3358 studies,finally including 59 studies describing 22 interventions.Most HP interventions were delivered in high income countries,included Caucasian men aged 35-65 years with overweight/obesity,and used professional sports clubs(mostly football)for recruitment and facilities.Quantitative HP outcomes were reported across 19 interventions.Of these 19 interventions,the majority reported on weight(n=18),physical activity(n=12),mental health(n=10),and diet(n=9).We identified 13 CMOs related to how HP interventions affected men's recruitment,engagement,and health behavior maintenance.Conclusion Our findings show that using sports clubs for HP interventions is effective for engaging men.Recruitment was facilitated by leveraging sports clubs’identity,addressing masculinity-related barriers,improving accessibility,and building trust.Engagement was enhanced through shared identity experiences,safe spaces,inclusive competition,and self-efficacy.However,there's limited evidence on behavior maintenance post-intervention,though involving community stakeholders seemed vital.In general,considerations should be made to avoid perpetuating traditional masculine norms,which may exclude some men and reinforce unhealthy behaviors.These findings can guide intervention development,emphasizing the need to harness men's perspectives in the process.展开更多
The hearing status of children should be examined throughout early childhood,even if they have passed the newborn hearing loss because hearing loss can occur at any time and may affect their ability to learn.Preschool...The hearing status of children should be examined throughout early childhood,even if they have passed the newborn hearing loss because hearing loss can occur at any time and may affect their ability to learn.Preschool hearing screening(PHS)is vital to continue screening throughout early childhood.The current practice of PHS in the primary healthcare centers(PHCs)in Saudi Arabia is unknown.The purpose of this study was to investigate PHS in the PHCs.This cross-sectional descriptive study used an in-person-administered questionnaire to collect data.A total of 106 out of 120 participants(male=61;female=45)representing the PHCs in Riyadh were interviewed.Most of the participants were aged 31–40 years and held a bachelor’s degree as the highest academic qualification with limited years of experience.PHS was mostly performed through subjective measures by asking the parents(71.7%)and the child(65.1%).The audiometric evaluation was conducted for preschool children in only half of the PHCs.General practitioners and nurses usually perform PHS.Substantial gaps in the practice of PHS were identified.The lack of training and appropriate instruments and the need for audiological services were the main challenges.Incorporating robust and objective protocols for PHS into the educational system is a valuable strategy for identifying hearing loss early and reducing its impact through the establishment of effective intervention plans.展开更多
Aim: To investigate depression, anxiety, PTSD, and insomnia levels among Sudanese citizens after a year has passed since the start of Armed Forces conflict in Sudan. Methods: An online survey was distributed. It is co...Aim: To investigate depression, anxiety, PTSD, and insomnia levels among Sudanese citizens after a year has passed since the start of Armed Forces conflict in Sudan. Methods: An online survey was distributed. It is composed of five parts, covering the following areas: 1) sociodemographic data;2) depression assessment;3) generalized anxiety disorder assessment;4) post-traumatic stress disorder assessment;and 5) insomnia assessment. Statistical Package for Social Sciences version 27 was used for data analysis;frequency and percentage were used to describe the qualitative variables. Spearman’s correlation analysis and Chi-square test were used for correlation and association analysis;a P-value equal to or less than 0.05 was considered statistically significant. Results: The study included 283 participants, primarily female (76.0%), with a mean age of 35.26 ± 6.96 years. The majority of participants were married (50.5%) and had a university level of education (50.2%). At the start of the war, 70.3% of participants were inside the war zones, and at the time of data collection, 73.5% were outside Sudan. The length of stay in the war zone ranged from 1 to 300 days, with a mean of 48.59 ± 70.284 days. Additionally, 63.3% of participants stated that they did not receive any form of mental health intervention, and the remaining did not provide an answer. There was a high prevalence of moderate-severe depression (50.5%), moderate anxiety (35.3%), PTSD (56.5%), and sub-threshold insomnia (53.4%) among the participants. Correlation analyses revealed associations between demographic factors such as sex, age, marital status, and education and mental health issues. Notably, female participants showed a higher prevalence of PTSD (53.0%) compared to male participants (67.6%). Conclusions: There is a substantial impact of war-related trauma on mental health, revealing a high prevalence of moderate-severe depression, moderate anxiety, PTSD, and sub-threshold insomnia among the participants. This emphasizes the importance of tailored interventions and support systems to address the unique needs of individuals affected by war trauma.展开更多
BACKGROUND While existing literature on ischiofemoral impingement syndrome(IFI)predominantly emphasizes surgical interventions or generalized physical therapy approaches,there remains a paucity of evidence regarding s...BACKGROUND While existing literature on ischiofemoral impingement syndrome(IFI)predominantly emphasizes surgical interventions or generalized physical therapy approaches,there remains a paucity of evidence regarding structured,multimodal rehabilitation programs targeting biomechanical deficits in IFI.This case report evaluates the efficacy of a multimodal rehabilitation program addressing a critical gap in conservative management strategies.CASE SUMMARY The patient underwent comprehensive physical and clinical examination,including hip X-ray and magnetic resonance imaging investigations.The patient completed the Musculoskeletal Health Questionnaire(MSK-HQ)and numerical pain rating scale(NPRS).The patient underwent a two-month tailored structured physical therapy intervention and repeated the same assessment afterwards.The patient's substantial reduction in pain,reflected by a significant decrease in the patient’s NPRS score from 9 to 3 points,signifies a positive clinical response.This outcome,coupled with the significant improvement in the patient's health-related quality of life according to the MSK-HQ score,which increased from 12 to 48 points,underscores the success of our research.CONCLUSION The study highlights the importance of a comprehensive approach to diagnosing and managing IFI,combining clinical assessment with imaging and implementing a multimodal rehabilitation program for optimal outcomes.展开更多
BACKGROUND Knee osteoarthritis(KOA)is a leading cause of arthritis-related morbidity.Mesenchymal stem cells(MSCs),as living biopharmaceuticals,have emerged as a potential treatment option due to their anti-inflammator...BACKGROUND Knee osteoarthritis(KOA)is a leading cause of arthritis-related morbidity.Mesenchymal stem cells(MSCs),as living biopharmaceuticals,have emerged as a potential treatment option due to their anti-inflammatory and immunomodulatory properties.AIM To compare the safety and efficacy of allogenic MSCs(^(Allo)MSCs)vs autologous MSCs(^(Auto)MSCs)in treating KOA in clinical settings.METHODS We conducted a systematic review and network meta-analysis to compare the safety and efficacy of^(Allo)MSCs vs^(Auto)MSCs in treating KOA.Our systematic search of four databases,including PubMed,Cochrane,Embase,and ClinicalTrials.gov,identified relevant randomized controlled trials(RCTs)reporting MSC-based treatment for KOA and reporting visual analog scale,Western Ontario and McMaster Universities Osteoarthritis scores,and adverse events.We assessed the methodological quality of the studies using the Cochrane Collaboration tool and calculated risk ratios(RRs)and weighted mean differences[with 95%confidence intervals(CIs)].Our statistical analyses used the R-Studio network meta-packages(version 2023.12.0).The study protocol was pre-registered on the International Prospective Register of Systematic Reviews(ID:CRD42024590866).RESULTS Nineteen RCTs involving 1216 patients with KOA met the inclusion criteria of the study.The network metaanalysis showed that^(Allo)MSCs gave a significant re-duction in visual analog scale scores by 14.91 points(95%CI:-24.52 to-5.30)vs 12.95 points with^(Auto)MSCs(95%CI:-24.42 to-1.48).For Western Ontario and McMaster Universities Osteoarthritis score,^(Allo)MSCs led to a significant reduction of 23.12 points(95%CI:-31.15 to-15.10)compared with 12.45 points using^(Auto)MSCs(95%CI:-19.31 to-5.59),thus revealing a significant improvement with^(Allo)MSCs(weighted mean difference:-10.62,95%CI:-21.23 to-0.11).Additionally,^(Auto)MSCs treatment showed a higher risk of joint-related adverse events(RR=1.39,95%CI:1.07-1.79)compared with^(Allo)MSCs(RR=1.13,95%CI:1.01-1.25).CONCLUSION^(Allo)MSCs may offer superior clinical outcomes with a lower risk of adverse events compared with^(Auto)MSCs in the treatment of KOA.However,the need for further RCTs directly comparing the two MSC types is crucial to validate this data,underscoring the importance of our findings in this field.展开更多
Background Sudden sensorineural hearing loss(SSNHL)is a rapid condition of hearing impairment,typically occurring over 72 hours and affecting the inner ear or auditory nerve pathways.The etiology of SSNHL remains larg...Background Sudden sensorineural hearing loss(SSNHL)is a rapid condition of hearing impairment,typically occurring over 72 hours and affecting the inner ear or auditory nerve pathways.The etiology of SSNHL remains largely idiopathic,with potential causes including viral infections,vascular occlusions,and autoimmune disorders.Traditional treatment primarily involves systemic corticosteroids,but their efficacy is inconsistent,leading to exploring alternative and adjunctive therapies such as intratympanic steroid(ITS)injections.Objective This Systematic Review and Meta-Analysis intends to determine the effectiveness of ITS injections as an initial treatment,combined therapy,or salvage treatment for SSNHL compared to systemic steroids alone.Methods An inclusive study was performed through the PubMed,Scopus,Web of Science,and Cochrane Library databases,encompassing publications published from 2015 to 2024.Case-control studies,cohort studies,randomized controlled trials(RCTs),and systematic reviews were included.Two separate reviewers read the studies and extracted data on steroid administration methods,study outcomes,and risk of bias(ROB)using the Cochrane Collaboration Tool and RevMan 5.4.Results The review included 12 studies with varied designs,including prospective RCTs,systematic reviews,and retrospective analyses.Combined ITS and systemic steroid therapy showed superior hearing recovery compared to systemic steroids alone in several studies.ITS alone demonstrated variable efficacy,with some studies indicating benefits,particularly as a salvage therapy.ROB assessment revealed variability in methodological rigor,with studies like those of Li&Ding et al.(2020)and Devantier et al.(2022)showing low risk,while others exhibited higher risks,particularly in random sequence generation and allocation concealment.Conclusion The findings suggest that ITS injections,particularly when combined with systemic steroids,can enhance hearing recovery in SSNHL patients.However,variability in study outcomes and methodological quality underscores the need for standardized protocols and further high-quality RCTs.This analysis underscores the prospective advantages of ITS therapy while stressing the need for stringent study designs to enhance SSNHL treatment methodologies.展开更多
Objective:To explore the effect of alantolactone on thioacetamide-induced liver fibrosis in mice as well as elucidate its underlying mechanism.Methods:Animals were divided into 5 groups:the control,the thioacetamide g...Objective:To explore the effect of alantolactone on thioacetamide-induced liver fibrosis in mice as well as elucidate its underlying mechanism.Methods:Animals were divided into 5 groups:the control,the thioacetamide group(150 mg/kg/twice weekly),the thioacetamide groups treated with alantolactone(5 and 10 mg/kg)or silymarin(50 mg/kg),respectively.All treatments were continued for 6 successive weeks,followed by collection of sera and tissue samples.Biochemical,histological,and immunohistochemical analyses were performed to examine the hepatoprotective effects of alantolactone.Results:Alantolactone ameliorated thioacetamide-induced hepatic impairment and prevented the rise of serum activities of liver enzymes.Its hepatoprotective effect was further confirmed by histological examinations.Moreover,alantolactone lowered the expression of transforming growth factor-beta 1 and alpha-smooth muscle actin,hydroxyproline content as well as COL1A1 mRNA expression.It restored antioxidant balance and inhibited thioacetamide-induced upregulated expression of interleukin-1 beta,interleukin-6,and tumor necrosis factor-alpha,Toll-like receptor 4(TLR4),myeloid differentiation primary response 88(MyD88),and nuclear factor kappa B(NF-κB).Conclusions:Alantolactone protects against thioacetamide-induced liver fibrosis in mice by reducing collagen deposition,oxidative stress,and inflammation.These effects are mediated,at least partly,by the inhibition of TLR4/MyD88/NF-κB axis.展开更多
BACKGROUND Arabic-speaking patients are underrepresented in orthopedic clinical studies,particularly in foot and ankle trauma research.The lack of validated Arabic language tools hinders their inclusion,creating a nee...BACKGROUND Arabic-speaking patients are underrepresented in orthopedic clinical studies,particularly in foot and ankle trauma research.The lack of validated Arabic language tools hinders their inclusion,creating a need for culturally and linguistically adapted instruments.The American Academy of Orthopedic Surgeons Foot and Ankle Outcomes Questionnaire(AAOS-FAOQ)is a widely used tool but has not been adapted for Arabic-speaking patients.AIM To translate,cross-culturally adapt,and validate the AAOS-FAOQ for Arabicspeaking patients with traumatic foot and ankle injuries.METHODS The cross-cultural adaptation followed established guidelines,involving forward and backward translations,expert review,and pre-testing.The final Arabic version was administered alongside the Arabic Short-Form 36(SF-36)to 100 patients for validity testing.Reliability was assessed through test-retest methods with 20 patients completing the questionnaire twice within 48 hours.Pearson correlation coefficients measured convergent and divergent validity with SF-36 subscales,while Cronbach's alpha and intraclass correlation coefficients(ICC)determined internal consistency and reliability.RESULTS Out of 100 patients,92 completed the first set of questionnaires.The Arabic AAOS-FAOQ showed strong correlations with the SF-36 subscales,particularly in physical function and bodily pain(r>0.6).Test-retest reliability was robust,with ICCs of 0.69 and 0.66 for the Global Foot and Ankle Scale and Shoe Comfort Scale,respectively.Cronbach's alpha for internal consistency ranged from 0.7 to 0.9.CONCLUSION The Arabic version of the AAOS-FAOQ demonstrated validity and reliability for use in Arabic-speaking patients with traumatic foot and ankle injuries.This adaptation will enhance the inclusion of this population in orthopedic clinical studies,improving the generalizability of research findings and patient care.展开更多
Objective: To assess the effectiveness of the created program in enhancing the knowledge of emergency room (ER) nurses in the emergency management of cardiovascular diseases (CVD). Methods: This study used a quasi-exp...Objective: To assess the effectiveness of the created program in enhancing the knowledge of emergency room (ER) nurses in the emergency management of cardiovascular diseases (CVD). Methods: This study used a quasi-experimental design with a one-group pretest-posttest research design to identify the knowledge and skills of emergency department (ED) nurses in managing CVD. There were 16 participants in this study. The mean, standard deviation (SD), and t-test were used to analyze the data. Results: Before the participants undergo the program, they have a mean (SD) score of 17.63 (5.19). After the completion of the didactic part of the program, they garnered a mean (SD) score of 19.94 (5.22). Moreover, after completion of the practicum part of the program, the mean (SD) score was 21.94 (5.04). Comparing the scores before the program and after finishing the didactic part of the program, the t-test scored (t (15) = -3.87, P = 0.001). Further, comparing the scores before the program and after finishing the didactic and practicum parts of the program, the t-test scored (t (15) = -5.57, P = 0.001). Conclusions: Based on the study’s results, the researchers conclude that the respondents had acceptable knowledge regarding the emergency management of CVD before the program. However, the Cardiac Enhancement Program for Emergency Cardiac Care boosted their knowledge. Also, the program is effective in enhancing the participants’ knowledge of the emergency management of CVD.展开更多
Background:Facelift procedures represent a critical area of aesthetic and reconstructive surgery that addresses the physical and psychological impacts of facial aging.Advancements in techniques and technologies over t...Background:Facelift procedures represent a critical area of aesthetic and reconstructive surgery that addresses the physical and psychological impacts of facial aging.Advancements in techniques and technologies over time have transformed the field,making it essential to assess the evolution of research trends.This study performed a bibliometric analysis of facelift research by examining the top 50 most cited publications to evaluate their contributions,thematic evolution,and collaborative networks.Methods:The Scopus database was used to identify relevant publications.A total of 50 documents were selected,comprising 47 articles and 3 reviews published across 16 academic sources.The inclusion criteria focused on publications with substantial relevance to facelift research;this ensured comprehensive coverage of the topic.Key performance indicators(for the authors)such as the number of papers,total citations,h-index,g-index,m-index,HG composite,and Q2 index were calculated.Citation analysis and collaborative network mapping were conducted to identify the leading contributors,including authors,universities,countries,and sources.Results:The findings indicated an annual growth rate of 1.34%,with an average document age of 29.4 years and an average citation count per document of 134.9.The analysis identified the top authors and their collaborative networks,along with key contributions from various universities,countries,and sources.The thematic evolution of facelift research was examined across these 50 papers;this revealed important trends and shifts within the field.Conclusion:This bibliometric analysis offers valuable insights into the development and influence of facelift research over a 52-year span.It highlights significant contributors and outlines thematic shifts,providing directions for future research and collaboration in this field.展开更多
BACKGROUND:In-flight medical emergencies(IMEs)present significant challenges to healthcare professionals,particularly those with limited training or experience in managing such situations.The objective of this study w...BACKGROUND:In-flight medical emergencies(IMEs)present significant challenges to healthcare professionals,particularly those with limited training or experience in managing such situations.The objective of this study was to evaluate the level of knowledge,attitudes,and behaviors of licensed doctors in Saudi Arabia concerning IMEs,and to identify the demographic factors influencing their preparedness.METHODS:A cross-sectional study was conducted with a sample of 383 licensed physicians across five regions of Saudi Arabia.Participants completed a self-administered questionnaire assessing demographics,knowledge of IMEs,attitudes towards providing assistance,and previous experience with in-flight emergencies.Data were analyzed using SPSS 26,with statistical significance set at P<0.05.RESULTS:The results revealed a predominantly young(75.8% aged 25-34 years)and male(69.6%)participant pool.While 76.6% of respondents recognized the impact of cabin pressure on oxygen,only 45.4% correctly identified air travel risks for asthmatic patients.Although 66.8% felt confident assisting in IMEs,20.9% cited medicolegal concerns.Moreover,area of working within Saudi Arabia(P=0.020),year of experience(P=0.041),prior experience with IMEs(P=0.021),and IMEs training(P<0.001)had a significant association with levels of knowledge.CONCLUSION:The study highlights a critical need for enhanced training programs with a focus on the management of IMEs among healthcare practitioners in Saudi Arabia.展开更多
BACKGROUND Tibial plateau fractures often require structural support for metaphyseal defects created during articular reduction.While autologous bone grafting has been utilized as the gold standard,bone substitutes of...BACKGROUND Tibial plateau fractures often require structural support for metaphyseal defects created during articular reduction.While autologous bone grafting has been utilized as the gold standard,bone substitutes offer advantages including reduced donor site morbidity.Our meta-analysis evaluated the comparative efficacy of these approaches across clinical and operative outcomes.AIM To conduct a systematic review and meta-analysis of randomized controlled trials comparing autologous bone grafts with bone substitutes for tibial plateau fractures.METHODS We conducted a systematic review and meta-analysis of randomized controlled trials comparing autologous bone grafts with bone substitutes for tibial plateau fractures.Primary outcomes included joint depression,secondary collapse rate,operative time,blood loss,and infection rate.Subgroup analyses were performed by fracture complexity,geographic region,and methodological factors.In addition to that,we also developed a combined outcome score integrating structural,procedural,and complication domains.RESULTS Seven randomized controlled trials with 424 patients(296 bone substitute,128 autograft)were included.No significant differences in joint depression or secondary collapse were observed across fracture complexity categories.Geographic variations were evident,with Western studies showing significantly higher risk of secondary collapse with autografts(risk ratio=1.45,P value=0.02).Both Western and Asian studies have demonstrated significantly reduced blood loss with bone substitutes(70-90 mL less),while operative time reduction was more significant in the Asian studies(23.65 vs 8.00 minutes,P value=0.04 for subgroup difference).The combined outcome score(standardized effect size-0.2481)favored bone substitutes,primarily due to procedural advantages.CONCLUSION Bone substitutes provide similar structural outcomes to autologous bone grafts while having better procedural advantages in tibial plateau fracture management.These findings support bone substitutes as a viable option across fracture patterns.Future studies should focus on specific bone substitute formulations and cost-effectiveness analyses.展开更多
The recent publication by Chekroud et al . in Lancet Psychiatry focuses on the relationship between physical exercise and mental health.Mental health is defined as optimal personal functioning "resulting in produ...The recent publication by Chekroud et al . in Lancet Psychiatry focuses on the relationship between physical exercise and mental health.Mental health is defined as optimal personal functioning "resulting in productive activities,fulfilling relationships with other people,and the ability to adapt to change and to cope with adversity".(p.4) Recently,mental health has no longer been described as a dichotomous state but as a continuum,with personal mental states ranging from highly functional to mentally ill.展开更多
Purpose: The aims of this study were to(1) investigate the health-related physical fitness profile of untrained adolescent boys in comparison to adolescent soccer players,(2) determine the intensity and enjoyment of 6...Purpose: The aims of this study were to(1) investigate the health-related physical fitness profile of untrained adolescent boys in comparison to adolescent soccer players,(2) determine the intensity and enjoyment of 6 v 6 and 4 v 4 small-sided games, and(3) evaluate the health-related effects of a short-period of soccer training in the untrained group.Methods: Forty-one adolescent boys(untrained, n = 24: age = 15.9 ± 0.6 years; trained, n = 17: age = 15.7 ± 0.7 years) were recruited. For Purpose 1,the players(n = 17) and the untrained(n = 24) boys were tested for speed, jumping power, postural balance, flexibility, and aerobic capacity. After baseline testing, Purposes 2 and 3 were addressed by randomly assigning the untrained boys to either a soccer-training group(small-sided games,2 sessions per week for 8 weeks) or to a control group, followed by identical retesting.Results: At baseline, physical fitness was higher(p < 0.001) in trained players than in untrained for aerobic fitness, sprinting, jumping power, and postural balance. Small-sided games using 6 v 6 or 4 v 4 elicited similar heart rate(HR)(mean: ~ 85% peak heart rate, HR_(peak)), rate of perceived exertion, and enjoyment responses. Over 8 weeks, the between-group analysis revealed that soccer training had a large beneficial effect on postural balance(45%) when compared with control group with unclear effects on other fitness parameters.Conclusion: Adolescent soccer players had markedly higher physical fitness compared with untrained adolescents. Small-sided soccer games practiced by untrained adolescents elicited high exercise intensity. While 8 weeks of twice-weekly soccer training sessions induced significant improvement in postural balance, the short duration of the study was not sufficient to result in between-group differences in sprint and jump performance or aerobic fitness.展开更多
Purpose: The aim of the present study was to investigate whether street basketball organized as 3 v 3 on either a half court(HC) with 1 basket or a full court(FC) with 2 baskets could improve fitness and health profil...Purpose: The aim of the present study was to investigate whether street basketball organized as 3 v 3 on either a half court(HC) with 1 basket or a full court(FC) with 2 baskets could improve fitness and health profiles of untrained men after 3 months of supervised training.Methods: Thirty-five untrained men(aged 20—42 years) completed the pre-and post-intervention testing(FC: n = 13, HC: n = 12, CO(control):n = 10). The training attendance was 2.0 ± 0.4 and 1.9 ± 0.3 times per week in FC and HC, respectively. Mean heart rate(HR) was 83.8 ± 6.0 percent of maximal heart rate(%HR_(max)) and 84.5 ± 2.9 %HR_(max) in FC and HC, respectively.Results: The 3 months of street basketball training on an FC with 2 baskets increased maximal oxygen uptake(2.4 mL/min/kg(95% confidence interval(CI): 1.0—3.9)), time to exhaustion(47 s(95%CI: 26—67)), lean body mass(0.8 kg(95%CI: 0.1—1.5)), and bone mineral density(0.021 g/cm^2(95%CI: 0.011—0.031)), whereas mean arterial pressure(—5.6 mm Hg(95%CI: —7.5 to 3.7)), body fat percentage(—1.6%,(95%CI: —2.5 to —0.7)), heart rate(—18 bpm(95%CI: —24 to —12)), and blood lactate(median: —1.4 mmol/L(interquartile range: —1.5 to —0.6)) during submaximal running were lowered. The changes were less pronounced after the training period when playing on an HC with 1 basket, but increases in maximal oxygen uptake(1.6 mL/min/kg(95%CI: —0.1 to 3.3)), time to exhaustion(28 s(95%CI: 9—47)), lean body mass(1.3 kg(95%CI: 0.3—2.4)), and lower body fat percentage(—0.9%(95%CI: —1.9 to —0.1)) were observed in this group.Conclusion: Three months of 3 v 3 street basketball training improved fitness and led to broad-spectrum improvements in variables related to overall health profile, with the most marked effects observed when playing on an FC with 2 baskets.展开更多
Purpose: The present study evaluated the effects of regular participation in small-sided team handball training on body composition, osteogenic response, physical performance, and cardiovascular risk factors, as well ...Purpose: The present study evaluated the effects of regular participation in small-sided team handball training on body composition, osteogenic response, physical performance, and cardiovascular risk factors, as well as well-being and motivation, in young untrained women.Methods: Twenty-eight untrained 20- to 30-year-old women were randomized to a handball training group(HG; n = 14, height 170 ± 5 cm, weight 73 ± 11 kg, VO_(2peak) 37.7 ± 4.1 mL/min/kg) that trained 1.7 ± 0.3 times per week over 12 weeks(70 min 4 v 4 handball sessions) or an inactive control group(CG; n = 14, 169 ± 5 cm, 71 ± 12 kg, 38.1 ± 3.7 mL/min/kg). Physiological and psychological and motivational training adaptations were assessed pre-and post-intervention by dual-energy X-ray Absorptiometry(DXA) scans, blood sampling, physical tests, and questionnaires.Results: The average heart rate(HR) over all training sessions was equal to 85% ± 6% HR_(max). Between-group intervention effects were observed in favor of HG for muscle mass(2.1%, p = 0.024), proximal femur bone mineral density(0.8%, p = 0.041), Yo-Yo IE1 intermittent endurance test level 1(IE1) performance(35%, p < 0.001), and incremental treadmill test performance(11.5%, p = 0.003), but not total fat mass(p = 0.176),mean arterial blood pressure(p = 0.328), resting HR(p = 0.219), or blood lipids(p = 0.298—0.854). In CG, no changes were observed in any of the measured physiological variables after the training period. Compared to CG, HG had an increase in intrinsic motivation(p < 0.001) and in the well-being subscale "energy"(p = 0.010).Conclusion: Participation in regular recreational team handball training organized as small-sided games has marked beneficial effects on physical performance, musculoskeletal fitness, well-being, and motivation in untrained young women.展开更多
Background:Adopting a healthy lifestyle during childhood could improve physical and mental health outcomes in adulthood and reduce relevant disease burdens.However,the lifestyles of children with mental,behavioral,and...Background:Adopting a healthy lifestyle during childhood could improve physical and mental health outcomes in adulthood and reduce relevant disease burdens.However,the lifestyles of children with mental,behavioral,and developmental disorders(MBDDs)remains under-described within the literature of public health field.This study aimed to examine adherence to 24-hour movement guidelines among children with MBDDs compared to population norms and whether these differences are affected by demographic characteristics.Methods:Data were from the 2016-2020 National Survey of Children’s Health—A national,population-based,cross-sectional study.We used the data of 119,406 children aged 6-17 years,which included 38,571 participants with at least 1 MBDD and 80,835 without.Adherence to the 24-hour movement guidelines was measured using parent-reported physical activity,screen time,and sleep duration.Results:Among children with MBDDs,20.3%,37.0%,60.7%,and 77.3%met the physical activity,screen time,sleep,and at least 1 of the 24-hour movement guidelines.These rates were lower than those in children without MBDDs(22.8%,46.2%,66.7%,and 83.4%,respectively;all p<0.001).Children with MBDDs were less likely to meet these guidelines(odds ratio(OR)=1.21,95%confidence interval(95%CI):1.13-1.30;OR=1.37,95%CI:1.29-1.45;OR=1.29,95%CI:1.21-1.37;OR=1.45,95%CI:1.35-1.56)than children without MBDDs.Children with emotional disorders had the highest odds of not meeting these guidelines(OR=1.43,95%CI:1.29-1.57;OR=1.48,95%CI:1.37-1.60;OR=1.49,95%CI:1.39-1.61;OR=1.72,95%CI:1.57-1.88)in comparison to children with other MBDDs.Among children aged12-17 years,the difference in proportion of meeting physical activity and screen time guidelines for children with vs.children without MBDD was larger than that among children aged 6-11 years.Furthermore,the above difference of meeting physical activity guidelines in ethnic minority children was smaller than that in white children.Conclusion:Children with MBDDs were less likely to meet individual or combined 24-hour movement guidelines than children without MBDDs.In educational and clinical settings,the primary focus should be on increasing physical activity and limiting screen time in children aged 12-17 years who have MBDDs;and specifically for white children who have MBDDs,increasing physical activity may help.展开更多
Introduction: Volunteering is an unpaid voluntary activity that provides some services to one or more other people or the community at large. Volunteer in the medical field is common. Physicians and medical students a...Introduction: Volunteering is an unpaid voluntary activity that provides some services to one or more other people or the community at large. Volunteer in the medical field is common. Physicians and medical students are participating in voluntary activities. This study assessed the motivations and barriers of Family Medicine (FM) Residents and Primary Health Care (PHC) Physicians in Qassim Region, Saudi Arabia. Methods: This is a descriptive cross-sectional study was carried out between 12th March 2021 to 31st September 2021 in Qassim Region, Saudi Arabia. 63 FM residents and 89 PHC physicians were involved. A self-administered questionnaire using Volunteer Functions Inventory (VFI) questions was distributed. A 30-item questionnaire is divided into 6 scales of 5 items each, which are scored using a 5-point Likert-type scale (where 1 strongly disagrees and 5 strongly agree). Results: Of 152 FM residents and PHC physicians, 91 (59.9%) were males, and Saudi 90 (59.2%). The mean age was 35 (±SD8.6) years. The majority of respondents 126 (85.7%) participated in different kinds of volunteer work. The highest rank of the benefits selected 137 (90.1%) was gained Allah’s pleasure. About 66 (43.4%) of respondents reported different reasons as barriers;lack of time was the dominant reason for 59 (38.8%). A strong statistical association was found between gender and facing barriers (P-value Conclusions: This study highlighted that the values motivation factor was the highest among the six motivation determinants. The main reason preventing respondents from doing voluntary work was the lack of time. Male gender and Saudi nationality physicians participated more in previous voluntary work P-value < 0.001. Further future research into studying human behaviour towards voluntary work is highly needed.展开更多
Background:Physicalfitness in childhood and adolescence is associated with a variety of health outcomes and is a powerful marker of current and future health.However,inconsistencies in tests and protocols limit interna...Background:Physicalfitness in childhood and adolescence is associated with a variety of health outcomes and is a powerful marker of current and future health.However,inconsistencies in tests and protocols limit international monitoring and surveillance.The objective of the study was to seek international consensus on a proposed,evidence-informed,Youth Fitness International Test(YFIT)battery and protocols for health monitoring and surveillance in children and adolescents aged 618 years.Methods:We conducted an international modified Delphi study to evaluate the level of agreement with a proposed,evidence-based,YFIT of core health-relatedfitness tests and protocols to be used worldwide in 6-to 18-year-olds.This proposal was based on previous European and North American projects that systematically reviewed the existing evidence to identify the most valid,reliable,health-related,safe,and feasiblefitness tests to be used in children and adolescents aged 618 years.We designed a single-panel modified Delphi study and invited 216 experts from all around the world to answer this Delphi survey,of whom one-third are from low-to-middle income countries and one-third are women.Four experts were involved in the piloting of the survey and did not participate in the main Delphi study to avoid bias.We pre-defined an agreement of 80%among the expert participants to achieve consensus.Results:We obtained a high response rate(78%)with a total of 169fitness experts from 50 countries and territories,including 63 women and 61 experts from low-or middle-income countries/territories.Consensus(>85%agreement)was achieved for all proposed tests and protocols,supporting the YFIT battery,which includes weight and height(to compute body mass index as a proxy of body size/composition),the 20-m shuttle run(cardiorespiratoryfitness),handgrip strength,and standing long jump(muscularfitness).Conclusion:This study contributes to standardizingfitness tests and protocols used for research,monitoring,and surveillance across the world,which will allow for future data pooling and the development of international and regional sex-and age-specific reference values,health-related cut-points,and a global picture offitness among children and adolescents.展开更多
This research focuses on the effects of migration on the TB infection rate and its prevention in Saudi Arabia, which has a large number of expatriates from TB-affected countries. Despite, based on the current global s...This research focuses on the effects of migration on the TB infection rate and its prevention in Saudi Arabia, which has a large number of expatriates from TB-affected countries. Despite, based on the current global statistics of TB occurrence, it is evident that the national incidence of TB has reduced from 10.55 per 100,000 in 2015 to 8.36 per 100,000 in 2019;despite this, there are still some difficulties because migrants bring new strains of Mycobacterium tuberculosis. Hindrances, including language barriers and perceived immigration status, hinder patients from seeking medical attention or doctors from diagnosing diseases. Each patient and each cultural group need special attention to public health, enhancing living circumstances, and health care support. Community participation, inclusion of TB control programs into functional healthcare facilities, and the functioning of TB programs need to be stressed to address TB issues. Considering the focus on social, economic, and cultural approaches, the country can make severe advancements in TB control and population protection. This holistic analysis is critical for a long-term effective strategy to combat TB in the Kingdom.展开更多
基金supported by the 5 Steno Diabetes Centers in Denmark,which are partly funded by the Novo Nordisk Foundation.
文摘Background Health promotion(HP)interventions delivered through sports clubs have demonstrated promising outcomes among men,but less is known about which aspects of the interventions work,for whom,and under what circumstances.This rapid realist review aimed to understand the contexts,mechanisms,and outcomes of HP interventions for men delivered through sports clubs.Methods A systematic literature search was conducted in February 2023 for studies published after 2013 in MEDLINE,Embase,and SPORTDiscus databases.Included studies:(a)were delivered by or in collaboration with sports clubs,(b)targeted men aged 18+years,and(c)reported 1 or more HP outcomes.A grey literature search was also performed.Studies were included in a realist synthesis based on richness and rigor.Hereafter,context-mechanism-outcome(CMO)configurations were developed.Results We identified and screened 3358 studies,finally including 59 studies describing 22 interventions.Most HP interventions were delivered in high income countries,included Caucasian men aged 35-65 years with overweight/obesity,and used professional sports clubs(mostly football)for recruitment and facilities.Quantitative HP outcomes were reported across 19 interventions.Of these 19 interventions,the majority reported on weight(n=18),physical activity(n=12),mental health(n=10),and diet(n=9).We identified 13 CMOs related to how HP interventions affected men's recruitment,engagement,and health behavior maintenance.Conclusion Our findings show that using sports clubs for HP interventions is effective for engaging men.Recruitment was facilitated by leveraging sports clubs’identity,addressing masculinity-related barriers,improving accessibility,and building trust.Engagement was enhanced through shared identity experiences,safe spaces,inclusive competition,and self-efficacy.However,there's limited evidence on behavior maintenance post-intervention,though involving community stakeholders seemed vital.In general,considerations should be made to avoid perpetuating traditional masculine norms,which may exclude some men and reinforce unhealthy behaviors.These findings can guide intervention development,emphasizing the need to harness men's perspectives in the process.
文摘The hearing status of children should be examined throughout early childhood,even if they have passed the newborn hearing loss because hearing loss can occur at any time and may affect their ability to learn.Preschool hearing screening(PHS)is vital to continue screening throughout early childhood.The current practice of PHS in the primary healthcare centers(PHCs)in Saudi Arabia is unknown.The purpose of this study was to investigate PHS in the PHCs.This cross-sectional descriptive study used an in-person-administered questionnaire to collect data.A total of 106 out of 120 participants(male=61;female=45)representing the PHCs in Riyadh were interviewed.Most of the participants were aged 31–40 years and held a bachelor’s degree as the highest academic qualification with limited years of experience.PHS was mostly performed through subjective measures by asking the parents(71.7%)and the child(65.1%).The audiometric evaluation was conducted for preschool children in only half of the PHCs.General practitioners and nurses usually perform PHS.Substantial gaps in the practice of PHS were identified.The lack of training and appropriate instruments and the need for audiological services were the main challenges.Incorporating robust and objective protocols for PHS into the educational system is a valuable strategy for identifying hearing loss early and reducing its impact through the establishment of effective intervention plans.
文摘Aim: To investigate depression, anxiety, PTSD, and insomnia levels among Sudanese citizens after a year has passed since the start of Armed Forces conflict in Sudan. Methods: An online survey was distributed. It is composed of five parts, covering the following areas: 1) sociodemographic data;2) depression assessment;3) generalized anxiety disorder assessment;4) post-traumatic stress disorder assessment;and 5) insomnia assessment. Statistical Package for Social Sciences version 27 was used for data analysis;frequency and percentage were used to describe the qualitative variables. Spearman’s correlation analysis and Chi-square test were used for correlation and association analysis;a P-value equal to or less than 0.05 was considered statistically significant. Results: The study included 283 participants, primarily female (76.0%), with a mean age of 35.26 ± 6.96 years. The majority of participants were married (50.5%) and had a university level of education (50.2%). At the start of the war, 70.3% of participants were inside the war zones, and at the time of data collection, 73.5% were outside Sudan. The length of stay in the war zone ranged from 1 to 300 days, with a mean of 48.59 ± 70.284 days. Additionally, 63.3% of participants stated that they did not receive any form of mental health intervention, and the remaining did not provide an answer. There was a high prevalence of moderate-severe depression (50.5%), moderate anxiety (35.3%), PTSD (56.5%), and sub-threshold insomnia (53.4%) among the participants. Correlation analyses revealed associations between demographic factors such as sex, age, marital status, and education and mental health issues. Notably, female participants showed a higher prevalence of PTSD (53.0%) compared to male participants (67.6%). Conclusions: There is a substantial impact of war-related trauma on mental health, revealing a high prevalence of moderate-severe depression, moderate anxiety, PTSD, and sub-threshold insomnia among the participants. This emphasizes the importance of tailored interventions and support systems to address the unique needs of individuals affected by war trauma.
文摘BACKGROUND While existing literature on ischiofemoral impingement syndrome(IFI)predominantly emphasizes surgical interventions or generalized physical therapy approaches,there remains a paucity of evidence regarding structured,multimodal rehabilitation programs targeting biomechanical deficits in IFI.This case report evaluates the efficacy of a multimodal rehabilitation program addressing a critical gap in conservative management strategies.CASE SUMMARY The patient underwent comprehensive physical and clinical examination,including hip X-ray and magnetic resonance imaging investigations.The patient completed the Musculoskeletal Health Questionnaire(MSK-HQ)and numerical pain rating scale(NPRS).The patient underwent a two-month tailored structured physical therapy intervention and repeated the same assessment afterwards.The patient's substantial reduction in pain,reflected by a significant decrease in the patient’s NPRS score from 9 to 3 points,signifies a positive clinical response.This outcome,coupled with the significant improvement in the patient's health-related quality of life according to the MSK-HQ score,which increased from 12 to 48 points,underscores the success of our research.CONCLUSION The study highlights the importance of a comprehensive approach to diagnosing and managing IFI,combining clinical assessment with imaging and implementing a multimodal rehabilitation program for optimal outcomes.
文摘BACKGROUND Knee osteoarthritis(KOA)is a leading cause of arthritis-related morbidity.Mesenchymal stem cells(MSCs),as living biopharmaceuticals,have emerged as a potential treatment option due to their anti-inflammatory and immunomodulatory properties.AIM To compare the safety and efficacy of allogenic MSCs(^(Allo)MSCs)vs autologous MSCs(^(Auto)MSCs)in treating KOA in clinical settings.METHODS We conducted a systematic review and network meta-analysis to compare the safety and efficacy of^(Allo)MSCs vs^(Auto)MSCs in treating KOA.Our systematic search of four databases,including PubMed,Cochrane,Embase,and ClinicalTrials.gov,identified relevant randomized controlled trials(RCTs)reporting MSC-based treatment for KOA and reporting visual analog scale,Western Ontario and McMaster Universities Osteoarthritis scores,and adverse events.We assessed the methodological quality of the studies using the Cochrane Collaboration tool and calculated risk ratios(RRs)and weighted mean differences[with 95%confidence intervals(CIs)].Our statistical analyses used the R-Studio network meta-packages(version 2023.12.0).The study protocol was pre-registered on the International Prospective Register of Systematic Reviews(ID:CRD42024590866).RESULTS Nineteen RCTs involving 1216 patients with KOA met the inclusion criteria of the study.The network metaanalysis showed that^(Allo)MSCs gave a significant re-duction in visual analog scale scores by 14.91 points(95%CI:-24.52 to-5.30)vs 12.95 points with^(Auto)MSCs(95%CI:-24.42 to-1.48).For Western Ontario and McMaster Universities Osteoarthritis score,^(Allo)MSCs led to a significant reduction of 23.12 points(95%CI:-31.15 to-15.10)compared with 12.45 points using^(Auto)MSCs(95%CI:-19.31 to-5.59),thus revealing a significant improvement with^(Allo)MSCs(weighted mean difference:-10.62,95%CI:-21.23 to-0.11).Additionally,^(Auto)MSCs treatment showed a higher risk of joint-related adverse events(RR=1.39,95%CI:1.07-1.79)compared with^(Allo)MSCs(RR=1.13,95%CI:1.01-1.25).CONCLUSION^(Allo)MSCs may offer superior clinical outcomes with a lower risk of adverse events compared with^(Auto)MSCs in the treatment of KOA.However,the need for further RCTs directly comparing the two MSC types is crucial to validate this data,underscoring the importance of our findings in this field.
文摘Background Sudden sensorineural hearing loss(SSNHL)is a rapid condition of hearing impairment,typically occurring over 72 hours and affecting the inner ear or auditory nerve pathways.The etiology of SSNHL remains largely idiopathic,with potential causes including viral infections,vascular occlusions,and autoimmune disorders.Traditional treatment primarily involves systemic corticosteroids,but their efficacy is inconsistent,leading to exploring alternative and adjunctive therapies such as intratympanic steroid(ITS)injections.Objective This Systematic Review and Meta-Analysis intends to determine the effectiveness of ITS injections as an initial treatment,combined therapy,or salvage treatment for SSNHL compared to systemic steroids alone.Methods An inclusive study was performed through the PubMed,Scopus,Web of Science,and Cochrane Library databases,encompassing publications published from 2015 to 2024.Case-control studies,cohort studies,randomized controlled trials(RCTs),and systematic reviews were included.Two separate reviewers read the studies and extracted data on steroid administration methods,study outcomes,and risk of bias(ROB)using the Cochrane Collaboration Tool and RevMan 5.4.Results The review included 12 studies with varied designs,including prospective RCTs,systematic reviews,and retrospective analyses.Combined ITS and systemic steroid therapy showed superior hearing recovery compared to systemic steroids alone in several studies.ITS alone demonstrated variable efficacy,with some studies indicating benefits,particularly as a salvage therapy.ROB assessment revealed variability in methodological rigor,with studies like those of Li&Ding et al.(2020)and Devantier et al.(2022)showing low risk,while others exhibited higher risks,particularly in random sequence generation and allocation concealment.Conclusion The findings suggest that ITS injections,particularly when combined with systemic steroids,can enhance hearing recovery in SSNHL patients.However,variability in study outcomes and methodological quality underscores the need for standardized protocols and further high-quality RCTs.This analysis underscores the prospective advantages of ITS therapy while stressing the need for stringent study designs to enhance SSNHL treatment methodologies.
文摘Objective:To explore the effect of alantolactone on thioacetamide-induced liver fibrosis in mice as well as elucidate its underlying mechanism.Methods:Animals were divided into 5 groups:the control,the thioacetamide group(150 mg/kg/twice weekly),the thioacetamide groups treated with alantolactone(5 and 10 mg/kg)or silymarin(50 mg/kg),respectively.All treatments were continued for 6 successive weeks,followed by collection of sera and tissue samples.Biochemical,histological,and immunohistochemical analyses were performed to examine the hepatoprotective effects of alantolactone.Results:Alantolactone ameliorated thioacetamide-induced hepatic impairment and prevented the rise of serum activities of liver enzymes.Its hepatoprotective effect was further confirmed by histological examinations.Moreover,alantolactone lowered the expression of transforming growth factor-beta 1 and alpha-smooth muscle actin,hydroxyproline content as well as COL1A1 mRNA expression.It restored antioxidant balance and inhibited thioacetamide-induced upregulated expression of interleukin-1 beta,interleukin-6,and tumor necrosis factor-alpha,Toll-like receptor 4(TLR4),myeloid differentiation primary response 88(MyD88),and nuclear factor kappa B(NF-κB).Conclusions:Alantolactone protects against thioacetamide-induced liver fibrosis in mice by reducing collagen deposition,oxidative stress,and inflammation.These effects are mediated,at least partly,by the inhibition of TLR4/MyD88/NF-κB axis.
文摘BACKGROUND Arabic-speaking patients are underrepresented in orthopedic clinical studies,particularly in foot and ankle trauma research.The lack of validated Arabic language tools hinders their inclusion,creating a need for culturally and linguistically adapted instruments.The American Academy of Orthopedic Surgeons Foot and Ankle Outcomes Questionnaire(AAOS-FAOQ)is a widely used tool but has not been adapted for Arabic-speaking patients.AIM To translate,cross-culturally adapt,and validate the AAOS-FAOQ for Arabicspeaking patients with traumatic foot and ankle injuries.METHODS The cross-cultural adaptation followed established guidelines,involving forward and backward translations,expert review,and pre-testing.The final Arabic version was administered alongside the Arabic Short-Form 36(SF-36)to 100 patients for validity testing.Reliability was assessed through test-retest methods with 20 patients completing the questionnaire twice within 48 hours.Pearson correlation coefficients measured convergent and divergent validity with SF-36 subscales,while Cronbach's alpha and intraclass correlation coefficients(ICC)determined internal consistency and reliability.RESULTS Out of 100 patients,92 completed the first set of questionnaires.The Arabic AAOS-FAOQ showed strong correlations with the SF-36 subscales,particularly in physical function and bodily pain(r>0.6).Test-retest reliability was robust,with ICCs of 0.69 and 0.66 for the Global Foot and Ankle Scale and Shoe Comfort Scale,respectively.Cronbach's alpha for internal consistency ranged from 0.7 to 0.9.CONCLUSION The Arabic version of the AAOS-FAOQ demonstrated validity and reliability for use in Arabic-speaking patients with traumatic foot and ankle injuries.This adaptation will enhance the inclusion of this population in orthopedic clinical studies,improving the generalizability of research findings and patient care.
文摘Objective: To assess the effectiveness of the created program in enhancing the knowledge of emergency room (ER) nurses in the emergency management of cardiovascular diseases (CVD). Methods: This study used a quasi-experimental design with a one-group pretest-posttest research design to identify the knowledge and skills of emergency department (ED) nurses in managing CVD. There were 16 participants in this study. The mean, standard deviation (SD), and t-test were used to analyze the data. Results: Before the participants undergo the program, they have a mean (SD) score of 17.63 (5.19). After the completion of the didactic part of the program, they garnered a mean (SD) score of 19.94 (5.22). Moreover, after completion of the practicum part of the program, the mean (SD) score was 21.94 (5.04). Comparing the scores before the program and after finishing the didactic part of the program, the t-test scored (t (15) = -3.87, P = 0.001). Further, comparing the scores before the program and after finishing the didactic and practicum parts of the program, the t-test scored (t (15) = -5.57, P = 0.001). Conclusions: Based on the study’s results, the researchers conclude that the respondents had acceptable knowledge regarding the emergency management of CVD before the program. However, the Cardiac Enhancement Program for Emergency Cardiac Care boosted their knowledge. Also, the program is effective in enhancing the participants’ knowledge of the emergency management of CVD.
文摘Background:Facelift procedures represent a critical area of aesthetic and reconstructive surgery that addresses the physical and psychological impacts of facial aging.Advancements in techniques and technologies over time have transformed the field,making it essential to assess the evolution of research trends.This study performed a bibliometric analysis of facelift research by examining the top 50 most cited publications to evaluate their contributions,thematic evolution,and collaborative networks.Methods:The Scopus database was used to identify relevant publications.A total of 50 documents were selected,comprising 47 articles and 3 reviews published across 16 academic sources.The inclusion criteria focused on publications with substantial relevance to facelift research;this ensured comprehensive coverage of the topic.Key performance indicators(for the authors)such as the number of papers,total citations,h-index,g-index,m-index,HG composite,and Q2 index were calculated.Citation analysis and collaborative network mapping were conducted to identify the leading contributors,including authors,universities,countries,and sources.Results:The findings indicated an annual growth rate of 1.34%,with an average document age of 29.4 years and an average citation count per document of 134.9.The analysis identified the top authors and their collaborative networks,along with key contributions from various universities,countries,and sources.The thematic evolution of facelift research was examined across these 50 papers;this revealed important trends and shifts within the field.Conclusion:This bibliometric analysis offers valuable insights into the development and influence of facelift research over a 52-year span.It highlights significant contributors and outlines thematic shifts,providing directions for future research and collaboration in this field.
基金approved by the Regional Research Ethics Committee,Qassim Province,Saudi Arabia.Number(607-45-12634).
文摘BACKGROUND:In-flight medical emergencies(IMEs)present significant challenges to healthcare professionals,particularly those with limited training or experience in managing such situations.The objective of this study was to evaluate the level of knowledge,attitudes,and behaviors of licensed doctors in Saudi Arabia concerning IMEs,and to identify the demographic factors influencing their preparedness.METHODS:A cross-sectional study was conducted with a sample of 383 licensed physicians across five regions of Saudi Arabia.Participants completed a self-administered questionnaire assessing demographics,knowledge of IMEs,attitudes towards providing assistance,and previous experience with in-flight emergencies.Data were analyzed using SPSS 26,with statistical significance set at P<0.05.RESULTS:The results revealed a predominantly young(75.8% aged 25-34 years)and male(69.6%)participant pool.While 76.6% of respondents recognized the impact of cabin pressure on oxygen,only 45.4% correctly identified air travel risks for asthmatic patients.Although 66.8% felt confident assisting in IMEs,20.9% cited medicolegal concerns.Moreover,area of working within Saudi Arabia(P=0.020),year of experience(P=0.041),prior experience with IMEs(P=0.021),and IMEs training(P<0.001)had a significant association with levels of knowledge.CONCLUSION:The study highlights a critical need for enhanced training programs with a focus on the management of IMEs among healthcare practitioners in Saudi Arabia.
文摘BACKGROUND Tibial plateau fractures often require structural support for metaphyseal defects created during articular reduction.While autologous bone grafting has been utilized as the gold standard,bone substitutes offer advantages including reduced donor site morbidity.Our meta-analysis evaluated the comparative efficacy of these approaches across clinical and operative outcomes.AIM To conduct a systematic review and meta-analysis of randomized controlled trials comparing autologous bone grafts with bone substitutes for tibial plateau fractures.METHODS We conducted a systematic review and meta-analysis of randomized controlled trials comparing autologous bone grafts with bone substitutes for tibial plateau fractures.Primary outcomes included joint depression,secondary collapse rate,operative time,blood loss,and infection rate.Subgroup analyses were performed by fracture complexity,geographic region,and methodological factors.In addition to that,we also developed a combined outcome score integrating structural,procedural,and complication domains.RESULTS Seven randomized controlled trials with 424 patients(296 bone substitute,128 autograft)were included.No significant differences in joint depression or secondary collapse were observed across fracture complexity categories.Geographic variations were evident,with Western studies showing significantly higher risk of secondary collapse with autografts(risk ratio=1.45,P value=0.02).Both Western and Asian studies have demonstrated significantly reduced blood loss with bone substitutes(70-90 mL less),while operative time reduction was more significant in the Asian studies(23.65 vs 8.00 minutes,P value=0.04 for subgroup difference).The combined outcome score(standardized effect size-0.2481)favored bone substitutes,primarily due to procedural advantages.CONCLUSION Bone substitutes provide similar structural outcomes to autologous bone grafts while having better procedural advantages in tibial plateau fracture management.These findings support bone substitutes as a viable option across fracture patterns.Future studies should focus on specific bone substitute formulations and cost-effectiveness analyses.
文摘The recent publication by Chekroud et al . in Lancet Psychiatry focuses on the relationship between physical exercise and mental health.Mental health is defined as optimal personal functioning "resulting in productive activities,fulfilling relationships with other people,and the ability to adapt to change and to cope with adversity".(p.4) Recently,mental health has no longer been described as a dichotomous state but as a continuum,with personal mental states ranging from highly functional to mentally ill.
文摘Purpose: The aims of this study were to(1) investigate the health-related physical fitness profile of untrained adolescent boys in comparison to adolescent soccer players,(2) determine the intensity and enjoyment of 6 v 6 and 4 v 4 small-sided games, and(3) evaluate the health-related effects of a short-period of soccer training in the untrained group.Methods: Forty-one adolescent boys(untrained, n = 24: age = 15.9 ± 0.6 years; trained, n = 17: age = 15.7 ± 0.7 years) were recruited. For Purpose 1,the players(n = 17) and the untrained(n = 24) boys were tested for speed, jumping power, postural balance, flexibility, and aerobic capacity. After baseline testing, Purposes 2 and 3 were addressed by randomly assigning the untrained boys to either a soccer-training group(small-sided games,2 sessions per week for 8 weeks) or to a control group, followed by identical retesting.Results: At baseline, physical fitness was higher(p < 0.001) in trained players than in untrained for aerobic fitness, sprinting, jumping power, and postural balance. Small-sided games using 6 v 6 or 4 v 4 elicited similar heart rate(HR)(mean: ~ 85% peak heart rate, HR_(peak)), rate of perceived exertion, and enjoyment responses. Over 8 weeks, the between-group analysis revealed that soccer training had a large beneficial effect on postural balance(45%) when compared with control group with unclear effects on other fitness parameters.Conclusion: Adolescent soccer players had markedly higher physical fitness compared with untrained adolescents. Small-sided soccer games practiced by untrained adolescents elicited high exercise intensity. While 8 weeks of twice-weekly soccer training sessions induced significant improvement in postural balance, the short duration of the study was not sufficient to result in between-group differences in sprint and jump performance or aerobic fitness.
文摘Purpose: The aim of the present study was to investigate whether street basketball organized as 3 v 3 on either a half court(HC) with 1 basket or a full court(FC) with 2 baskets could improve fitness and health profiles of untrained men after 3 months of supervised training.Methods: Thirty-five untrained men(aged 20—42 years) completed the pre-and post-intervention testing(FC: n = 13, HC: n = 12, CO(control):n = 10). The training attendance was 2.0 ± 0.4 and 1.9 ± 0.3 times per week in FC and HC, respectively. Mean heart rate(HR) was 83.8 ± 6.0 percent of maximal heart rate(%HR_(max)) and 84.5 ± 2.9 %HR_(max) in FC and HC, respectively.Results: The 3 months of street basketball training on an FC with 2 baskets increased maximal oxygen uptake(2.4 mL/min/kg(95% confidence interval(CI): 1.0—3.9)), time to exhaustion(47 s(95%CI: 26—67)), lean body mass(0.8 kg(95%CI: 0.1—1.5)), and bone mineral density(0.021 g/cm^2(95%CI: 0.011—0.031)), whereas mean arterial pressure(—5.6 mm Hg(95%CI: —7.5 to 3.7)), body fat percentage(—1.6%,(95%CI: —2.5 to —0.7)), heart rate(—18 bpm(95%CI: —24 to —12)), and blood lactate(median: —1.4 mmol/L(interquartile range: —1.5 to —0.6)) during submaximal running were lowered. The changes were less pronounced after the training period when playing on an HC with 1 basket, but increases in maximal oxygen uptake(1.6 mL/min/kg(95%CI: —0.1 to 3.3)), time to exhaustion(28 s(95%CI: 9—47)), lean body mass(1.3 kg(95%CI: 0.3—2.4)), and lower body fat percentage(—0.9%(95%CI: —1.9 to —0.1)) were observed in this group.Conclusion: Three months of 3 v 3 street basketball training improved fitness and led to broad-spectrum improvements in variables related to overall health profile, with the most marked effects observed when playing on an FC with 2 baskets.
基金financial support by TrygFondenNordea-fonden (Nordea-fonden 02-2011-4360)+2 种基金the Danish Handball Federation (Dansk Ha ndbold Forbund, DHF)the European Handball Federation (EHF)funded in part by the Danish and European Handball Federation
文摘Purpose: The present study evaluated the effects of regular participation in small-sided team handball training on body composition, osteogenic response, physical performance, and cardiovascular risk factors, as well as well-being and motivation, in young untrained women.Methods: Twenty-eight untrained 20- to 30-year-old women were randomized to a handball training group(HG; n = 14, height 170 ± 5 cm, weight 73 ± 11 kg, VO_(2peak) 37.7 ± 4.1 mL/min/kg) that trained 1.7 ± 0.3 times per week over 12 weeks(70 min 4 v 4 handball sessions) or an inactive control group(CG; n = 14, 169 ± 5 cm, 71 ± 12 kg, 38.1 ± 3.7 mL/min/kg). Physiological and psychological and motivational training adaptations were assessed pre-and post-intervention by dual-energy X-ray Absorptiometry(DXA) scans, blood sampling, physical tests, and questionnaires.Results: The average heart rate(HR) over all training sessions was equal to 85% ± 6% HR_(max). Between-group intervention effects were observed in favor of HG for muscle mass(2.1%, p = 0.024), proximal femur bone mineral density(0.8%, p = 0.041), Yo-Yo IE1 intermittent endurance test level 1(IE1) performance(35%, p < 0.001), and incremental treadmill test performance(11.5%, p = 0.003), but not total fat mass(p = 0.176),mean arterial blood pressure(p = 0.328), resting HR(p = 0.219), or blood lipids(p = 0.298—0.854). In CG, no changes were observed in any of the measured physiological variables after the training period. Compared to CG, HG had an increase in intrinsic motivation(p < 0.001) and in the well-being subscale "energy"(p = 0.010).Conclusion: Participation in regular recreational team handball training organized as small-sided games has marked beneficial effects on physical performance, musculoskeletal fitness, well-being, and motivation in untrained young women.
基金financial support of the Key-Area Research and Development Program of Guangdong Province(2019B030335001)the National Natural Science Foundation of China(82103794)+2 种基金Guangdong Basic and Applied Basic Research Foundation(2021A1515011757)General Administration of Sport of China and China Institute of Sport Science(19—21)Guangxi Key Research and Development Plan(GUIKEAB18050024)。
文摘Background:Adopting a healthy lifestyle during childhood could improve physical and mental health outcomes in adulthood and reduce relevant disease burdens.However,the lifestyles of children with mental,behavioral,and developmental disorders(MBDDs)remains under-described within the literature of public health field.This study aimed to examine adherence to 24-hour movement guidelines among children with MBDDs compared to population norms and whether these differences are affected by demographic characteristics.Methods:Data were from the 2016-2020 National Survey of Children’s Health—A national,population-based,cross-sectional study.We used the data of 119,406 children aged 6-17 years,which included 38,571 participants with at least 1 MBDD and 80,835 without.Adherence to the 24-hour movement guidelines was measured using parent-reported physical activity,screen time,and sleep duration.Results:Among children with MBDDs,20.3%,37.0%,60.7%,and 77.3%met the physical activity,screen time,sleep,and at least 1 of the 24-hour movement guidelines.These rates were lower than those in children without MBDDs(22.8%,46.2%,66.7%,and 83.4%,respectively;all p<0.001).Children with MBDDs were less likely to meet these guidelines(odds ratio(OR)=1.21,95%confidence interval(95%CI):1.13-1.30;OR=1.37,95%CI:1.29-1.45;OR=1.29,95%CI:1.21-1.37;OR=1.45,95%CI:1.35-1.56)than children without MBDDs.Children with emotional disorders had the highest odds of not meeting these guidelines(OR=1.43,95%CI:1.29-1.57;OR=1.48,95%CI:1.37-1.60;OR=1.49,95%CI:1.39-1.61;OR=1.72,95%CI:1.57-1.88)in comparison to children with other MBDDs.Among children aged12-17 years,the difference in proportion of meeting physical activity and screen time guidelines for children with vs.children without MBDD was larger than that among children aged 6-11 years.Furthermore,the above difference of meeting physical activity guidelines in ethnic minority children was smaller than that in white children.Conclusion:Children with MBDDs were less likely to meet individual or combined 24-hour movement guidelines than children without MBDDs.In educational and clinical settings,the primary focus should be on increasing physical activity and limiting screen time in children aged 12-17 years who have MBDDs;and specifically for white children who have MBDDs,increasing physical activity may help.
文摘Introduction: Volunteering is an unpaid voluntary activity that provides some services to one or more other people or the community at large. Volunteer in the medical field is common. Physicians and medical students are participating in voluntary activities. This study assessed the motivations and barriers of Family Medicine (FM) Residents and Primary Health Care (PHC) Physicians in Qassim Region, Saudi Arabia. Methods: This is a descriptive cross-sectional study was carried out between 12th March 2021 to 31st September 2021 in Qassim Region, Saudi Arabia. 63 FM residents and 89 PHC physicians were involved. A self-administered questionnaire using Volunteer Functions Inventory (VFI) questions was distributed. A 30-item questionnaire is divided into 6 scales of 5 items each, which are scored using a 5-point Likert-type scale (where 1 strongly disagrees and 5 strongly agree). Results: Of 152 FM residents and PHC physicians, 91 (59.9%) were males, and Saudi 90 (59.2%). The mean age was 35 (±SD8.6) years. The majority of respondents 126 (85.7%) participated in different kinds of volunteer work. The highest rank of the benefits selected 137 (90.1%) was gained Allah’s pleasure. About 66 (43.4%) of respondents reported different reasons as barriers;lack of time was the dominant reason for 59 (38.8%). A strong statistical association was found between gender and facing barriers (P-value Conclusions: This study highlighted that the values motivation factor was the highest among the six motivation determinants. The main reason preventing respondents from doing voluntary work was the lack of time. Male gender and Saudi nationality physicians participated more in previous voluntary work P-value < 0.001. Further future research into studying human behaviour towards voluntary work is highly needed.
基金supported by the Grant PID2020-120249RB-I00PID2023-148404OB-100funded by MCIN/AEI/10.13039/501100011033+4 种基金by the Andalusian Government(Junta de Andalucía,Plan Andaluz de Investigación,ref.P20_00124)by the Erasmus+Sport Programme of the European Union within the project FitBack4Literacy(No.101089829)Additional support is provided by the University of Granada,Plan Propio de Inves-tigación,Units of ExcellenceUnit of Excellence on Exercise,Nutrition and Health(UCEENS)by theCIBERobn Physiopa-thology of Obesity and Nutrition,and by the Spanish Network in Exercise and Health,EXERNET Network(RED2022-134800-Tand EXP_99828).
文摘Background:Physicalfitness in childhood and adolescence is associated with a variety of health outcomes and is a powerful marker of current and future health.However,inconsistencies in tests and protocols limit international monitoring and surveillance.The objective of the study was to seek international consensus on a proposed,evidence-informed,Youth Fitness International Test(YFIT)battery and protocols for health monitoring and surveillance in children and adolescents aged 618 years.Methods:We conducted an international modified Delphi study to evaluate the level of agreement with a proposed,evidence-based,YFIT of core health-relatedfitness tests and protocols to be used worldwide in 6-to 18-year-olds.This proposal was based on previous European and North American projects that systematically reviewed the existing evidence to identify the most valid,reliable,health-related,safe,and feasiblefitness tests to be used in children and adolescents aged 618 years.We designed a single-panel modified Delphi study and invited 216 experts from all around the world to answer this Delphi survey,of whom one-third are from low-to-middle income countries and one-third are women.Four experts were involved in the piloting of the survey and did not participate in the main Delphi study to avoid bias.We pre-defined an agreement of 80%among the expert participants to achieve consensus.Results:We obtained a high response rate(78%)with a total of 169fitness experts from 50 countries and territories,including 63 women and 61 experts from low-or middle-income countries/territories.Consensus(>85%agreement)was achieved for all proposed tests and protocols,supporting the YFIT battery,which includes weight and height(to compute body mass index as a proxy of body size/composition),the 20-m shuttle run(cardiorespiratoryfitness),handgrip strength,and standing long jump(muscularfitness).Conclusion:This study contributes to standardizingfitness tests and protocols used for research,monitoring,and surveillance across the world,which will allow for future data pooling and the development of international and regional sex-and age-specific reference values,health-related cut-points,and a global picture offitness among children and adolescents.
文摘This research focuses on the effects of migration on the TB infection rate and its prevention in Saudi Arabia, which has a large number of expatriates from TB-affected countries. Despite, based on the current global statistics of TB occurrence, it is evident that the national incidence of TB has reduced from 10.55 per 100,000 in 2015 to 8.36 per 100,000 in 2019;despite this, there are still some difficulties because migrants bring new strains of Mycobacterium tuberculosis. Hindrances, including language barriers and perceived immigration status, hinder patients from seeking medical attention or doctors from diagnosing diseases. Each patient and each cultural group need special attention to public health, enhancing living circumstances, and health care support. Community participation, inclusion of TB control programs into functional healthcare facilities, and the functioning of TB programs need to be stressed to address TB issues. Considering the focus on social, economic, and cultural approaches, the country can make severe advancements in TB control and population protection. This holistic analysis is critical for a long-term effective strategy to combat TB in the Kingdom.
