In the classroom,teachers usually find that students fail to remain focused and think actively.This relatively low classroom participation also affects students'reading and writing abilities.Therefore,it has been ...In the classroom,teachers usually find that students fail to remain focused and think actively.This relatively low classroom participation also affects students'reading and writing abilities.Therefore,it has been a common concern of educational researchers and practitioners worldwide to understand how students'initiative can be stimulated and how students can be fostered to become self-driven readers,thinkers,and writers.Catherine Snow is an expert on language and literacy development in children.展开更多
This study aims to investigate the current status of AI competencies among Chinese high school students using quantitative research methods.By integrating UNESCO’s AI Competency Framework for Students with China’s e...This study aims to investigate the current status of AI competencies among Chinese high school students using quantitative research methods.By integrating UNESCO’s AI Competency Framework for Students with China’s educational practices,a questionnaire was developed.Altogether,300 students from eight high schools joined the research.SPSS 26.0 was used for reliability and validity tests,exploratory factor analysis,and group difference analysis.The results show that the questionnaire has good reliability and validity(Cronbach’sα=0.974,KMO=0.912,Bartlett’s test of sphericity was significant with p<0.001,cumulative variance explained 72.0%).Besides,Chinese high school students’AI competencies exhibit a typical pattern of“strong in technology,weak in ethics,and insufficient in creativity”,with technical application ability(mean=3.7)significantly higher than ethical assessment(mean=3.0)and system design(mean=2.8).What’s more,students in the eastern region have significantly better overall competencies than those in the central and western regions(p<0.05),with the largest gap in the technical application dimension(mean difference=0.7)and the smallest gap in the ethical dimension(mean difference=0.3).The study recommends optimizing high school curricula by adding modules for ethical debates and interdisciplinary projects and promoting equitable distribution of educational resources.This research empirically supports global AI education standardization and offers a scientific basis for AI education policies and curriculum design in China’s high schools.展开更多
BACKGROUND Sex education was introduced early in foreign countries.For example,there is a more systematic sex education system abroad,which can better achieve the popularization of sex education.China's sex educat...BACKGROUND Sex education was introduced early in foreign countries.For example,there is a more systematic sex education system abroad,which can better achieve the popularization of sex education.China's sex education started relatively late,yet there are many problems in the development of sex education in China;for example,college students lack knowledge of sexuality.AIM To explore the perception of sex education among medical college students.METHODS Students majoring in medicine in a medical school were selected as the survey subjects.Anonymous online questionnaires were used to conduct the survey,and the results were analyzed using GraphPad Prism,SPSS,Microsoft Excel,and other software.The questionnaire was administered to understand the source of sexual knowledge,sexual responsibility,mastery of sexual knowledge,and distress caused by sexual problems.RESULTS Most students majoring in medicine had no formal sex education,lacked sexual knowledge,or had a biased understanding of sexual responsibility.This study analyzed future research trends in sex education based on relevant achievements in the Chinese context and abroad to further realize the practical significance and value of sex education popularization in China and provide recommendations for parents and schools at different levels.CONCLUSION Sex education should be conducted among college students,and medical colleges and universities should strengthen scientific sex education.展开更多
Questionnaires and interviews are employed in this paper to investigate and analyze the situation with respect to express packaging waste at the Graduate School of the Chinese Academy of Social Sciences(GCASS).The sur...Questionnaires and interviews are employed in this paper to investigate and analyze the situation with respect to express packaging waste at the Graduate School of the Chinese Academy of Social Sciences(GCASS).The survey results show that:(1)the campus receives a large number of express packages and there is,in turn,a considerable amount of packaging waste;(2)there are four main types of express packaging materials:paper packaging,plastic bags,wrapping tapes and package fillers;(3)neither the students nor the school perform well in the recycling of express packaging waste;(4)the samples investigated in this paper can be divided into four categories by cluster analysis,and the author infers from this that the colleges and universities with a large proportion of female students should pay more attention to the issue of recycling of express packaging waste.Several suggestions are presented based on the research results:(1)establishing a campus waste recycling system is the most efficient way to solve the problem of express packaging waste at GCASS;(2)we should advocate for green packaging and manage it from the source of waste generation because most of the express packaging material does not easily degrade naturally,and this represents a huge hidden danger to human health and the environment;(3)the school should cultivate student awareness of environmental protection.If education and penalties are implemented together,the recovery system will run better.展开更多
The exploration of the way"mass entrepreneurship and innovation"(MEI)education influences students'aspirations to become entrepreneurs has grown into an important area of analysis in studies related to h...The exploration of the way"mass entrepreneurship and innovation"(MEI)education influences students'aspirations to become entrepreneurs has grown into an important area of analysis in studies related to higher education.This research intends to examine the consequences of MEI education on students'tendency towards entrepreneurship,and to put forward methods for augmenting the teaching of innovation and entrepreneurship in private higher educational establishments.To achieve this objective,questionnaires and semi-structured interviews were employed in the study,which involved a total of 197 students and five education experts.The statistical analysis of the questionnaire data revealed that MEI education was positively related to students'entrepreneurial intentions,and that both entrepreneurial experience and family entrepreneurial background played moderating roles in this relationship.The interview findings indicated that private universities could enhance educational reforms by designing talent training programs,developing diversified curricula,and developing more professional entrepreneurial platforms to encourage students'entrepreneurial intentions.This study offers fresh insights for improving and perfecting the mechanism of innovation and entrepreneurship education in private universities.展开更多
Aim: Recently, the role of feeding coparenting has gained attention in the child eating research field. The Feeding Coparenting Scale (FCS), a measure of how caregivers interact with their partners when feeding their ...Aim: Recently, the role of feeding coparenting has gained attention in the child eating research field. The Feeding Coparenting Scale (FCS), a measure of how caregivers interact with their partners when feeding their children was developed in the United States in 2019. However, there is no valid and reliable measure to assess feeding coparenting among caregivers of school-aged children in Japan. Therefore, this study aimed to develop a Japanese version of the FCS (FCS-J) questionnaire for caregivers with school-aged children. Methods: This was a web-based cross-sectional survey completed by caregivers of children aged 10-12 years. A preliminary survey using interviews and a web-based survey was conducted and found that the translated items of the FCS into Japanese were understandable to Japanese people. The developed survey was administered to parents of children at an elementary school. The reliability of the survey was assessed using both test-retest reliability and internal consistency analysis. Exploratory factor analysis was used to test construct validity, and known population validity was examined in relation to attributes, marital satisfaction, and feeding tasks. Results: Findings with 135 parents of school-aged children showed good internal reliability and validity of the FCS-J. The mean score for the overall FCS-J score was 46.2 (SD = 6.2), with Cronbach’s α of 0.72. For the subscales, Cronbach’s α ranged from 0.75 to 0.79. In sum, the present study’s results support the three-factor structure of the FCS in Japanese caregivers in Japan. Conclusions: The developed FCS-J was found to have a certain degree of reliability and validity. In this study, a Japanese version of the FCS-J was developed. .展开更多
This study aims to investigate the influence of social media on college choice among undergraduates majoring in Big Data Management and Application in China.The study attempts to reveal how information on social media...This study aims to investigate the influence of social media on college choice among undergraduates majoring in Big Data Management and Application in China.The study attempts to reveal how information on social media platforms such as Weibo,WeChat,and Zhihu influences the cognition and choice process of prospective students.By employing an online quantitative survey questionnaire,data were collected from the 2022 and 2023 classes of new students majoring in Big Data Management and Application at Guilin University of Electronic Technology.The aim was to evaluate the role of social media in their college choice process and understand the features and information that most attract prospective students.Social media has become a key factor influencing the college choice decision-making of undergraduates majoring in Big Data Management and Application in China.Students tend to obtain school information through social media platforms and use this information as an important reference in their decision-making process.Higher education institutions should strengthen their social media information dissemination,providing accurate,timely,and attractive information.It is also necessary to ensure effective management of social media platforms,maintain a positive reputation for the school on social media,and increase the interest and trust of prospective students.Simultaneously,educational decision-makers should consider incorporating social media analysis into their recruitment strategies to better attract new student enrollment.This study provides a new perspective for understanding higher education choice behavior in the digital age,particularly by revealing the importance of social media in the educational decision-making process.This has important practical and theoretical implications for higher education institutions,policymakers,and social media platform operators.展开更多
With the wave of education digitalization,the reform of graduate education has gradually become an important issue in the reform of innovative personnel training.This paper discusses the necessity of the digital trans...With the wave of education digitalization,the reform of graduate education has gradually become an important issue in the reform of innovative personnel training.This paper discusses the necessity of the digital transformation of graduate education,analyzes the current difficulties and challenges,and proposes relevant reform suggestions in response to the current predicament,providing important references for graduate education reform and innovation.展开更多
Against the background of the“double first-class”construction,the training of innovative graduate talent has become an important issue in higher education.This article discusses the importance of the training of top...Against the background of the“double first-class”construction,the training of innovative graduate talent has become an important issue in higher education.This article discusses the importance of the training of top graduate innovative talent,analyzes the status of the training of top graduate innovative talent at home and abroad,and summarizes the current challenges in the training of graduate innovative talent in China.Lastly,this paper proposes relevant reform suggestions in response to problems in the training of innovative graduate talent,which provides important references for improving the quality of innovative graduate training.展开更多
Aneurysm rupture can result in subarachnoid hemorrhage,a condition with potentially severe consequences,such as disability and death.In the acute stage,early brain injury manifests as intracranial pressure elevation,g...Aneurysm rupture can result in subarachnoid hemorrhage,a condition with potentially severe consequences,such as disability and death.In the acute stage,early brain injury manifests as intracranial pressure elevation,global cerebral ischemia,acute hydrocephalus,and direct blood–brain contact due to aneurysm rupture.This may subsequently cause delayed cerebral infarction,often with cerebral vasospasm,significantly affecting patient outcomes.Chronic complications such as brain volume loss and chronic hydrocephalus can further impact outcomes.Investigating the mechanisms of subarachnoid hemorrhage-induced brain injury is paramount for identifying effective treatments.Stem cell therapy,with its multipotent differentiation capacity and anti-inflammatory effects,has emerged as a promising approach for treating previously deemed incurable conditions.This review focuses on the potential application of stem cells in subarachnoid hemorrhage pathology and explores their role in neurogenesis and as a therapeutic intervention in preclinical and clinical subarachnoid hemorrhage studies.展开更多
Stroke causes neuronal loss,which ultimately results in persistent neurological dysfunction.Globally,stroke was the third-leading cause of death and disability combined in all ages in 2019,after neonatal disorders and...Stroke causes neuronal loss,which ultimately results in persistent neurological dysfunction.Globally,stroke was the third-leading cause of death and disability combined in all ages in 2019,after neonatal disorders and ischemic heart disease.In that year,there were 12.2 million incident strokes,101 million prevalent strokes,and 143 million disability-adjusted life-years due to stroke.展开更多
Spinal cord injury involves non-reversible damage to the central nervous system that is characterized by limited regenerative capacity and secondary inflammatory damage.The expression of the C-C motif chemokine ligand...Spinal cord injury involves non-reversible damage to the central nervous system that is characterized by limited regenerative capacity and secondary inflammatory damage.The expression of the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis exhibits significant differences before and after injury.Recent studies have revealed that the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis is closely associated with secondary inflammatory responses and the recruitment of immune cells following spinal cord injury,suggesting that this axis is a novel target and regulatory control point for treatment.This review comprehensively examines the therapeutic strategies targeting the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis,along with the regenerative and repair mechanisms linking the axis to spinal cord injury.Additionally,we summarize the upstream and downstream inflammatory signaling pathways associated with spinal cord injury and the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis.This review primarily elaborates on therapeutic strategies that target the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis and the latest progress of research on antagonistic drugs,along with the approaches used to exploit new therapeutic targets within the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis and the development of targeted drugs.Nevertheless,there are presently no clinical studies relating to spinal cord injury that are focusing on the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis.This review aims to provide new ideas and therapeutic strategies for the future treatment of spinal cord injury.展开更多
BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility disturbance.The pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling p...BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility disturbance.The pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling pathway associated with intestinal flora and Cajal stromal cells.Moreover,intestinal flora can also affect the regulation of SCF/c-kit signaling pathway,thus affecting the expression of Cajal stromal cells.Cajal cells are the pacemakers of gastrointestinal motility.AIM To investigate the effects of Bifidobacterium lactis(B.lactis)BLa80 on the intestinal flora of rats in simulated microgravity and on the gastrointestinal motility-related SCF/c-kit pathway.METHODS The internationally recognized tail suspension animal model was used to simulate the microgravity environment,and 30 rats were randomly divided into control group,tail suspension group and drug administration tail suspension group with 10 rats in each group for a total of 28 days.The tail group was given B.lactis BLa80 by intragastric administration,and the other two groups were given water intragastric administration,the concentration of intragastric administration was 0.1 g/mL,and each rat was 1 mL/day.Hematoxylin&eosin staining was used to observe the histopathological changes in each segment of the intestine of each group,and the expression levels of SCF,c-kit,extracellular signal-regulated kinase(ERK)and p-ERK in the gastric antrum of each group were detected by Western blotting and PCR.The fecal flora and mucosal flora of rats in each group were detected by 16S rRNA.RESULTS Simulated microgravity resulted in severe exfoliation of villi of duodenum,jejunum and ileum in rats,marked damage,increased space between villi,loose arrangement,shortened columnar epithelium of colon,less folds,narrower mucosal thickness,reduced goblet cell number and crypts,and significant improvement after probiotic intervention.Simulated microgravity reduced the expressions of SCF and c-kit,and increased the expressions of ERK and P-ERK in the gastric antrum of rats.However,after probiotic intervention,the expressions of SCF and ckit were increased,while the expressions of ERK and P-ERK were decreased,with statistical significance(P<0.05).In addition,simulated microgravity can reduce the operational taxonomic unit(OTU)of the overall intestinal flora of rats,B.lactis BLa80 can increase the OTU of rats,simulated microgravity can reduce the overall richness and diversity of stool flora of rats,increase the abundance of firmicutes in stool flora of rats,and reduce the abundance of Bacteroides in stool flora of rats,most of which are mainly beneficial bacteria.Simulated microgravity can increase the overall richness and diversity of mucosal flora,increase the abundance of Bacteroides and Desulphurides in the rat mucosal flora,and decrease the abundance of firmicutes,most of which are proteobacteria.After probiotics intervention,the overall Bacteroidetes trend in simulated microgravity rats was increased.CONCLUSION B.lactis BLa80 can ameliorate intestinal mucosal injury,regulate intestinal flora,inhibit ERK expression,and activate the SCF/c-kit signaling pathway,which may have a facilitating effect on gastrointestinal motility in simulated microgravity rats.展开更多
Protonic solid oxide electrolysis cells(P-SOECs)are a promising technology for water electrolysis to produce green hydrogen.However,there are still challenges related key materials and anode/electrolyte interface.P-SO...Protonic solid oxide electrolysis cells(P-SOECs)are a promising technology for water electrolysis to produce green hydrogen.However,there are still challenges related key materials and anode/electrolyte interface.P-SOECs with Zr-rich electrolyte,called Zr-rich side P-SOECs,possess high thermodynamically stability under high steam concentrations but the large reaction resistances and the current leakage,thus the inferior performances.In this study,an efficient functional interlayer Ba_(0.95)La_(0.05)Fe_(0.8)Zn_(0.2)O_(3-δ)(BLFZ)in-between the anode and the electrolyte is developed.The electrochemical performances of P-SOECs are greatly enhanced because the BLFZ can greatly increase the interface contact,boost anode reaction kinetics,and increase proton injection into electrolyte.As a result,the P-SOEC yields high current density of 0.83 A cm^(-2) at 600℃ in 1.3 Vamong all the reported Zr-rich side cells.This work not only offers an efficient functional interlayer for P-SOECs but also holds the potential to achieve P-SOECs with high performances and long-term stability.展开更多
Understanding the proton dynamic behavior in inorganic materials has long been a topic of intense fascination[1],especially in the field of electrochemical energy storage[2].One of the examples is the research of prot...Understanding the proton dynamic behavior in inorganic materials has long been a topic of intense fascination[1],especially in the field of electrochemical energy storage[2].One of the examples is the research of proton transport in transition metal oxides,which dates back to 1971[3]when RuO_(2) was discovered to be capable of storing protons via reversible redox reactions[4].In aqueous electrolytes,the thin film RuO_(2) electrode exhibits a surface pseudocapacitive behavior[5],which could be modified by the structural water in its hydrated form due to the facile Grotthuss hopping mode of protons along the established hydrogen bonds inside the bulk phase[6].Soon later,Goodenough et al.reported the capacitor-like behavior of amorphous MnO_(2)·xH_(2)O electrode in an aqueous KCl electrolyte[7],and further studies on the hydrated MnO_(2) electrodes prepared by sol-gel processes have soon discovered that the intercalation of protons from aqueous electrolytes plays an indispensable role in the charge storage mechanism[8].In recent years,the research interest on rechargeable aqueous batteries has fueled the renaissance of mechanistic study of proton transport in transition metal oxides[9],which can operate as cathodes or anodes via a topotactic insertion mechanism similar to that in Li-ion batteries[10].However,due to the challenges for experimental detection of local chemical environments of the inserted protons,a comprehensive understanding of proton dynamic behavior in these electrodes remains largely lacking.展开更多
Internal learning-based video inpainting methods have shown promising results by exploiting the intrinsic properties of the video to fill in the missing region without external dataset supervision.However,existing int...Internal learning-based video inpainting methods have shown promising results by exploiting the intrinsic properties of the video to fill in the missing region without external dataset supervision.However,existing internal learning-based video inpainting methods would produce inconsistent structures or blurry textures due to the insufficient utilisation of motion priors within the video sequence.In this paper,the authors propose a new internal learning-based video inpainting model called appearance consistency and motion coherence network(ACMC-Net),which can not only learn the recurrence of appearance prior but can also capture motion coherence prior to improve the quality of the inpainting results.In ACMC-Net,a transformer-based appearance network is developed to capture global context information within the video frame for representing appearance consistency accurately.Additionally,a novel motion coherence learning scheme is proposed to learn the motion prior in a video sequence effectively.Finally,the learnt internal appearance consistency and motion coherence are implicitly propagated to the missing regions to achieve inpainting well.Extensive experiments conducted on the DAVIS dataset show that the proposed model obtains the superior performance in terms of quantitative measurements and produces more visually plausible results compared with the state-of-the-art methods.展开更多
Background:Previous studies have highlighted the frequent occurrence of sarcopenia in patients with pancreatic diseases,including chronic pancreatitis.We aimed to clarify the prevalence of skeletal muscle(SM)loss and ...Background:Previous studies have highlighted the frequent occurrence of sarcopenia in patients with pancreatic diseases,including chronic pancreatitis.We aimed to clarify the prevalence of skeletal muscle(SM)loss and sarcopenia,and their associations with clinical characteristics,bone mineral density,and pancreatic imaging findings in patients with autoimmune pancreatitis(AIP).Methods:This study included 114 patients with AIP treated at Tohoku University Hospital.The SM index was assessed using a bioelectrical impedance analysis device,grip strength was measured using a hand dynamometer,and bone mineral density was evaluated using dual-energy X-ray absorptiometry.Univari-ate and multivariate logistic regression analyses were used to analyze factors associated with SM loss and sarcopenia.Results:Among 114 patients,57(50.0%)had SM loss,31(27.2%)had reduced grip strength,and 27(23.7%)had both.Patients with SM loss were older and had a lower body mass index,weaker grip strength,higher Controlling Nutritional Status scores,and lower serum lipase and albumin levels compared to those without SM loss.Computed tomography scans revealed a higher prevalence of pancreatic parenchy-mal atrophy in patients with SM loss.Similar differences were observed between patients with sarcopenia and those without.Osteopathy was observed in 35.6%of patients with SM loss and 38.1%of those with sarcopenia,whereas only 4.1%of patients without SM loss had osteopathy.Low BMI(<21.0 kg/m^(2))was also found to be an independent risk factor for SM loss in multivariate analysis.Age>72 years,low BMI(<20.0 kg/m^(2)),and low serum lipase levels(<13 U/L)were independent risk factors for sarcopenia in multivariate analysis.Conclusions:SM loss and sarcopenia are prevalent in patients with AIP and are associated with aging,poor nutritional status,low serum lipase levels,and pancreatic parenchymal atrophy.In addition to the high risk of osteopathy,careful attention should be paid to maintain muscle health in AIP patients.展开更多
文摘In the classroom,teachers usually find that students fail to remain focused and think actively.This relatively low classroom participation also affects students'reading and writing abilities.Therefore,it has been a common concern of educational researchers and practitioners worldwide to understand how students'initiative can be stimulated and how students can be fostered to become self-driven readers,thinkers,and writers.Catherine Snow is an expert on language and literacy development in children.
基金supported by Research Project on Humanities and Social Sciences in Higher Education Institutions of Guizhou Provincial Department of Education(No.24RWZX060).
文摘This study aims to investigate the current status of AI competencies among Chinese high school students using quantitative research methods.By integrating UNESCO’s AI Competency Framework for Students with China’s educational practices,a questionnaire was developed.Altogether,300 students from eight high schools joined the research.SPSS 26.0 was used for reliability and validity tests,exploratory factor analysis,and group difference analysis.The results show that the questionnaire has good reliability and validity(Cronbach’sα=0.974,KMO=0.912,Bartlett’s test of sphericity was significant with p<0.001,cumulative variance explained 72.0%).Besides,Chinese high school students’AI competencies exhibit a typical pattern of“strong in technology,weak in ethics,and insufficient in creativity”,with technical application ability(mean=3.7)significantly higher than ethical assessment(mean=3.0)and system design(mean=2.8).What’s more,students in the eastern region have significantly better overall competencies than those in the central and western regions(p<0.05),with the largest gap in the technical application dimension(mean difference=0.7)and the smallest gap in the ethical dimension(mean difference=0.3).The study recommends optimizing high school curricula by adding modules for ethical debates and interdisciplinary projects and promoting equitable distribution of educational resources.This research empirically supports global AI education standardization and offers a scientific basis for AI education policies and curriculum design in China’s high schools.
基金Supported by Scientific Research Project of College Students in Liaoning Province,No.S202410164004.
文摘BACKGROUND Sex education was introduced early in foreign countries.For example,there is a more systematic sex education system abroad,which can better achieve the popularization of sex education.China's sex education started relatively late,yet there are many problems in the development of sex education in China;for example,college students lack knowledge of sexuality.AIM To explore the perception of sex education among medical college students.METHODS Students majoring in medicine in a medical school were selected as the survey subjects.Anonymous online questionnaires were used to conduct the survey,and the results were analyzed using GraphPad Prism,SPSS,Microsoft Excel,and other software.The questionnaire was administered to understand the source of sexual knowledge,sexual responsibility,mastery of sexual knowledge,and distress caused by sexual problems.RESULTS Most students majoring in medicine had no formal sex education,lacked sexual knowledge,or had a biased understanding of sexual responsibility.This study analyzed future research trends in sex education based on relevant achievements in the Chinese context and abroad to further realize the practical significance and value of sex education popularization in China and provide recommendations for parents and schools at different levels.CONCLUSION Sex education should be conducted among college students,and medical colleges and universities should strengthen scientific sex education.
文摘Questionnaires and interviews are employed in this paper to investigate and analyze the situation with respect to express packaging waste at the Graduate School of the Chinese Academy of Social Sciences(GCASS).The survey results show that:(1)the campus receives a large number of express packages and there is,in turn,a considerable amount of packaging waste;(2)there are four main types of express packaging materials:paper packaging,plastic bags,wrapping tapes and package fillers;(3)neither the students nor the school perform well in the recycling of express packaging waste;(4)the samples investigated in this paper can be divided into four categories by cluster analysis,and the author infers from this that the colleges and universities with a large proportion of female students should pay more attention to the issue of recycling of express packaging waste.Several suggestions are presented based on the research results:(1)establishing a campus waste recycling system is the most efficient way to solve the problem of express packaging waste at GCASS;(2)we should advocate for green packaging and manage it from the source of waste generation because most of the express packaging material does not easily degrade naturally,and this represents a huge hidden danger to human health and the environment;(3)the school should cultivate student awareness of environmental protection.If education and penalties are implemented together,the recovery system will run better.
文摘The exploration of the way"mass entrepreneurship and innovation"(MEI)education influences students'aspirations to become entrepreneurs has grown into an important area of analysis in studies related to higher education.This research intends to examine the consequences of MEI education on students'tendency towards entrepreneurship,and to put forward methods for augmenting the teaching of innovation and entrepreneurship in private higher educational establishments.To achieve this objective,questionnaires and semi-structured interviews were employed in the study,which involved a total of 197 students and five education experts.The statistical analysis of the questionnaire data revealed that MEI education was positively related to students'entrepreneurial intentions,and that both entrepreneurial experience and family entrepreneurial background played moderating roles in this relationship.The interview findings indicated that private universities could enhance educational reforms by designing talent training programs,developing diversified curricula,and developing more professional entrepreneurial platforms to encourage students'entrepreneurial intentions.This study offers fresh insights for improving and perfecting the mechanism of innovation and entrepreneurship education in private universities.
文摘Aim: Recently, the role of feeding coparenting has gained attention in the child eating research field. The Feeding Coparenting Scale (FCS), a measure of how caregivers interact with their partners when feeding their children was developed in the United States in 2019. However, there is no valid and reliable measure to assess feeding coparenting among caregivers of school-aged children in Japan. Therefore, this study aimed to develop a Japanese version of the FCS (FCS-J) questionnaire for caregivers with school-aged children. Methods: This was a web-based cross-sectional survey completed by caregivers of children aged 10-12 years. A preliminary survey using interviews and a web-based survey was conducted and found that the translated items of the FCS into Japanese were understandable to Japanese people. The developed survey was administered to parents of children at an elementary school. The reliability of the survey was assessed using both test-retest reliability and internal consistency analysis. Exploratory factor analysis was used to test construct validity, and known population validity was examined in relation to attributes, marital satisfaction, and feeding tasks. Results: Findings with 135 parents of school-aged children showed good internal reliability and validity of the FCS-J. The mean score for the overall FCS-J score was 46.2 (SD = 6.2), with Cronbach’s α of 0.72. For the subscales, Cronbach’s α ranged from 0.75 to 0.79. In sum, the present study’s results support the three-factor structure of the FCS in Japanese caregivers in Japan. Conclusions: The developed FCS-J was found to have a certain degree of reliability and validity. In this study, a Japanese version of the FCS-J was developed. .
文摘This study aims to investigate the influence of social media on college choice among undergraduates majoring in Big Data Management and Application in China.The study attempts to reveal how information on social media platforms such as Weibo,WeChat,and Zhihu influences the cognition and choice process of prospective students.By employing an online quantitative survey questionnaire,data were collected from the 2022 and 2023 classes of new students majoring in Big Data Management and Application at Guilin University of Electronic Technology.The aim was to evaluate the role of social media in their college choice process and understand the features and information that most attract prospective students.Social media has become a key factor influencing the college choice decision-making of undergraduates majoring in Big Data Management and Application in China.Students tend to obtain school information through social media platforms and use this information as an important reference in their decision-making process.Higher education institutions should strengthen their social media information dissemination,providing accurate,timely,and attractive information.It is also necessary to ensure effective management of social media platforms,maintain a positive reputation for the school on social media,and increase the interest and trust of prospective students.Simultaneously,educational decision-makers should consider incorporating social media analysis into their recruitment strategies to better attract new student enrollment.This study provides a new perspective for understanding higher education choice behavior in the digital age,particularly by revealing the importance of social media in the educational decision-making process.This has important practical and theoretical implications for higher education institutions,policymakers,and social media platform operators.
基金Foundation for Development Research of Disciplines of China University of Geosciences(Beijing)(2022XK218 and 2023XK110)。
文摘With the wave of education digitalization,the reform of graduate education has gradually become an important issue in the reform of innovative personnel training.This paper discusses the necessity of the digital transformation of graduate education,analyzes the current difficulties and challenges,and proposes relevant reform suggestions in response to the current predicament,providing important references for graduate education reform and innovation.
基金Foundation for Development Research of Disciplines of China University of Geosciences(Beijing)(2022XK218 and 2023XK110)。
文摘Against the background of the“double first-class”construction,the training of innovative graduate talent has become an important issue in higher education.This article discusses the importance of the training of top graduate innovative talent,analyzes the status of the training of top graduate innovative talent at home and abroad,and summarizes the current challenges in the training of graduate innovative talent in China.Lastly,this paper proposes relevant reform suggestions in response to problems in the training of innovative graduate talent,which provides important references for improving the quality of innovative graduate training.
基金funded by Taiju Life Social Welfare Foundation(to HS).
文摘Aneurysm rupture can result in subarachnoid hemorrhage,a condition with potentially severe consequences,such as disability and death.In the acute stage,early brain injury manifests as intracranial pressure elevation,global cerebral ischemia,acute hydrocephalus,and direct blood–brain contact due to aneurysm rupture.This may subsequently cause delayed cerebral infarction,often with cerebral vasospasm,significantly affecting patient outcomes.Chronic complications such as brain volume loss and chronic hydrocephalus can further impact outcomes.Investigating the mechanisms of subarachnoid hemorrhage-induced brain injury is paramount for identifying effective treatments.Stem cell therapy,with its multipotent differentiation capacity and anti-inflammatory effects,has emerged as a promising approach for treating previously deemed incurable conditions.This review focuses on the potential application of stem cells in subarachnoid hemorrhage pathology and explores their role in neurogenesis and as a therapeutic intervention in preclinical and clinical subarachnoid hemorrhage studies.
基金supported by JSPS KAKENHI Grant Number JP24K18622(to TI)JSPS KAKENHI Grant Number JP23K18451(to TM)。
文摘Stroke causes neuronal loss,which ultimately results in persistent neurological dysfunction.Globally,stroke was the third-leading cause of death and disability combined in all ages in 2019,after neonatal disorders and ischemic heart disease.In that year,there were 12.2 million incident strokes,101 million prevalent strokes,and 143 million disability-adjusted life-years due to stroke.
基金supported by the National Natural Science Foundation of China(Key Program),No.11932013the National Natural Science Foundation of China(General Program),No.82272255+2 种基金Armed Police Force High-Level Science and Technology Personnel ProjectThe Armed Police Force Focuses on Supporting Scientific and Technological Innovation TeamsKey Project of Tianjin Science and Technology Plan,No.20JCZDJC00570(all to XC)。
文摘Spinal cord injury involves non-reversible damage to the central nervous system that is characterized by limited regenerative capacity and secondary inflammatory damage.The expression of the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis exhibits significant differences before and after injury.Recent studies have revealed that the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis is closely associated with secondary inflammatory responses and the recruitment of immune cells following spinal cord injury,suggesting that this axis is a novel target and regulatory control point for treatment.This review comprehensively examines the therapeutic strategies targeting the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis,along with the regenerative and repair mechanisms linking the axis to spinal cord injury.Additionally,we summarize the upstream and downstream inflammatory signaling pathways associated with spinal cord injury and the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis.This review primarily elaborates on therapeutic strategies that target the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis and the latest progress of research on antagonistic drugs,along with the approaches used to exploit new therapeutic targets within the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis and the development of targeted drugs.Nevertheless,there are presently no clinical studies relating to spinal cord injury that are focusing on the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis.This review aims to provide new ideas and therapeutic strategies for the future treatment of spinal cord injury.
文摘BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility disturbance.The pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling pathway associated with intestinal flora and Cajal stromal cells.Moreover,intestinal flora can also affect the regulation of SCF/c-kit signaling pathway,thus affecting the expression of Cajal stromal cells.Cajal cells are the pacemakers of gastrointestinal motility.AIM To investigate the effects of Bifidobacterium lactis(B.lactis)BLa80 on the intestinal flora of rats in simulated microgravity and on the gastrointestinal motility-related SCF/c-kit pathway.METHODS The internationally recognized tail suspension animal model was used to simulate the microgravity environment,and 30 rats were randomly divided into control group,tail suspension group and drug administration tail suspension group with 10 rats in each group for a total of 28 days.The tail group was given B.lactis BLa80 by intragastric administration,and the other two groups were given water intragastric administration,the concentration of intragastric administration was 0.1 g/mL,and each rat was 1 mL/day.Hematoxylin&eosin staining was used to observe the histopathological changes in each segment of the intestine of each group,and the expression levels of SCF,c-kit,extracellular signal-regulated kinase(ERK)and p-ERK in the gastric antrum of each group were detected by Western blotting and PCR.The fecal flora and mucosal flora of rats in each group were detected by 16S rRNA.RESULTS Simulated microgravity resulted in severe exfoliation of villi of duodenum,jejunum and ileum in rats,marked damage,increased space between villi,loose arrangement,shortened columnar epithelium of colon,less folds,narrower mucosal thickness,reduced goblet cell number and crypts,and significant improvement after probiotic intervention.Simulated microgravity reduced the expressions of SCF and c-kit,and increased the expressions of ERK and P-ERK in the gastric antrum of rats.However,after probiotic intervention,the expressions of SCF and ckit were increased,while the expressions of ERK and P-ERK were decreased,with statistical significance(P<0.05).In addition,simulated microgravity can reduce the operational taxonomic unit(OTU)of the overall intestinal flora of rats,B.lactis BLa80 can increase the OTU of rats,simulated microgravity can reduce the overall richness and diversity of stool flora of rats,increase the abundance of firmicutes in stool flora of rats,and reduce the abundance of Bacteroides in stool flora of rats,most of which are mainly beneficial bacteria.Simulated microgravity can increase the overall richness and diversity of mucosal flora,increase the abundance of Bacteroides and Desulphurides in the rat mucosal flora,and decrease the abundance of firmicutes,most of which are proteobacteria.After probiotics intervention,the overall Bacteroidetes trend in simulated microgravity rats was increased.CONCLUSION B.lactis BLa80 can ameliorate intestinal mucosal injury,regulate intestinal flora,inhibit ERK expression,and activate the SCF/c-kit signaling pathway,which may have a facilitating effect on gastrointestinal motility in simulated microgravity rats.
基金financial support from the JSPS KAKENHI Grant-in-Aid for Scientific Research(B),No.21H02035KAKENHI Grant-in-Aid for Challenging Research(Exploratory),No.21K19017+2 种基金KAKENHI Grant-in-Aid for Transformative Research Areas(B),No.21H05100National Natural Science Foundation of China,No.22409033 and No.22409035Basic and Applied Basic Research Foundation of Guangdong Province,No.2022A1515110470.
文摘Protonic solid oxide electrolysis cells(P-SOECs)are a promising technology for water electrolysis to produce green hydrogen.However,there are still challenges related key materials and anode/electrolyte interface.P-SOECs with Zr-rich electrolyte,called Zr-rich side P-SOECs,possess high thermodynamically stability under high steam concentrations but the large reaction resistances and the current leakage,thus the inferior performances.In this study,an efficient functional interlayer Ba_(0.95)La_(0.05)Fe_(0.8)Zn_(0.2)O_(3-δ)(BLFZ)in-between the anode and the electrolyte is developed.The electrochemical performances of P-SOECs are greatly enhanced because the BLFZ can greatly increase the interface contact,boost anode reaction kinetics,and increase proton injection into electrolyte.As a result,the P-SOEC yields high current density of 0.83 A cm^(-2) at 600℃ in 1.3 Vamong all the reported Zr-rich side cells.This work not only offers an efficient functional interlayer for P-SOECs but also holds the potential to achieve P-SOECs with high performances and long-term stability.
基金financial support from the National Natural Science Foundation of China(22109003)the Basic and Applied Basic Research Foundation of Guangdong Province(2023A1515011391)+1 种基金Soft Science Research Project of Guangdong Province(No.2017B030301013)the Major Science and Technology Infrastructure Project of Material Genome Big-science Facilities Platform supported by Municipal Development and Reform Commission of Shenzhen.
文摘Understanding the proton dynamic behavior in inorganic materials has long been a topic of intense fascination[1],especially in the field of electrochemical energy storage[2].One of the examples is the research of proton transport in transition metal oxides,which dates back to 1971[3]when RuO_(2) was discovered to be capable of storing protons via reversible redox reactions[4].In aqueous electrolytes,the thin film RuO_(2) electrode exhibits a surface pseudocapacitive behavior[5],which could be modified by the structural water in its hydrated form due to the facile Grotthuss hopping mode of protons along the established hydrogen bonds inside the bulk phase[6].Soon later,Goodenough et al.reported the capacitor-like behavior of amorphous MnO_(2)·xH_(2)O electrode in an aqueous KCl electrolyte[7],and further studies on the hydrated MnO_(2) electrodes prepared by sol-gel processes have soon discovered that the intercalation of protons from aqueous electrolytes plays an indispensable role in the charge storage mechanism[8].In recent years,the research interest on rechargeable aqueous batteries has fueled the renaissance of mechanistic study of proton transport in transition metal oxides[9],which can operate as cathodes or anodes via a topotactic insertion mechanism similar to that in Li-ion batteries[10].However,due to the challenges for experimental detection of local chemical environments of the inserted protons,a comprehensive understanding of proton dynamic behavior in these electrodes remains largely lacking.
基金Shenzhen Science and Technology Programme,Grant/Award Number:JCYJ202308071208000012023 Shenzhen sustainable supporting funds for colleges and universities,Grant/Award Number:20231121165240001Guangdong Provincial Key Laboratory of Ultra High Definition Immersive Media Technology,Grant/Award Number:2024B1212010006。
文摘Internal learning-based video inpainting methods have shown promising results by exploiting the intrinsic properties of the video to fill in the missing region without external dataset supervision.However,existing internal learning-based video inpainting methods would produce inconsistent structures or blurry textures due to the insufficient utilisation of motion priors within the video sequence.In this paper,the authors propose a new internal learning-based video inpainting model called appearance consistency and motion coherence network(ACMC-Net),which can not only learn the recurrence of appearance prior but can also capture motion coherence prior to improve the quality of the inpainting results.In ACMC-Net,a transformer-based appearance network is developed to capture global context information within the video frame for representing appearance consistency accurately.Additionally,a novel motion coherence learning scheme is proposed to learn the motion prior in a video sequence effectively.Finally,the learnt internal appearance consistency and motion coherence are implicitly propagated to the missing regions to achieve inpainting well.Extensive experiments conducted on the DAVIS dataset show that the proposed model obtains the superior performance in terms of quantitative measurements and produces more visually plausible results compared with the state-of-the-art methods.
基金supported in part by the Japan Pancreas Soci-ety and the MHLW Research Program on Rare and Intractable Dis-eases(Grant Number 23FC1015,Principal investigator:Mitsuhiro Kawano).
文摘Background:Previous studies have highlighted the frequent occurrence of sarcopenia in patients with pancreatic diseases,including chronic pancreatitis.We aimed to clarify the prevalence of skeletal muscle(SM)loss and sarcopenia,and their associations with clinical characteristics,bone mineral density,and pancreatic imaging findings in patients with autoimmune pancreatitis(AIP).Methods:This study included 114 patients with AIP treated at Tohoku University Hospital.The SM index was assessed using a bioelectrical impedance analysis device,grip strength was measured using a hand dynamometer,and bone mineral density was evaluated using dual-energy X-ray absorptiometry.Univari-ate and multivariate logistic regression analyses were used to analyze factors associated with SM loss and sarcopenia.Results:Among 114 patients,57(50.0%)had SM loss,31(27.2%)had reduced grip strength,and 27(23.7%)had both.Patients with SM loss were older and had a lower body mass index,weaker grip strength,higher Controlling Nutritional Status scores,and lower serum lipase and albumin levels compared to those without SM loss.Computed tomography scans revealed a higher prevalence of pancreatic parenchy-mal atrophy in patients with SM loss.Similar differences were observed between patients with sarcopenia and those without.Osteopathy was observed in 35.6%of patients with SM loss and 38.1%of those with sarcopenia,whereas only 4.1%of patients without SM loss had osteopathy.Low BMI(<21.0 kg/m^(2))was also found to be an independent risk factor for SM loss in multivariate analysis.Age>72 years,low BMI(<20.0 kg/m^(2)),and low serum lipase levels(<13 U/L)were independent risk factors for sarcopenia in multivariate analysis.Conclusions:SM loss and sarcopenia are prevalent in patients with AIP and are associated with aging,poor nutritional status,low serum lipase levels,and pancreatic parenchymal atrophy.In addition to the high risk of osteopathy,careful attention should be paid to maintain muscle health in AIP patients.
