Hemophagocytic lymphohistiocytosis(HLH)is a rare immune disorder characterized by uncontrolled activation of cytotoxic T lymphocytes(T cells),natural killer cells(NK cells),triggering a cytokine burst,and severe syste...Hemophagocytic lymphohistiocytosis(HLH)is a rare immune disorder characterized by uncontrolled activation of cytotoxic T lymphocytes(T cells),natural killer cells(NK cells),triggering a cytokine burst,and severe systemic hyperinflammation.1 HLH can be inherited or developed from infection,autoimmune/autoinflammatory disorders,and neoplasms.展开更多
基金partly funded by the U.S.Department of Agriculture’s(USDA)Animal Health Project NC 07090.
文摘Hemophagocytic lymphohistiocytosis(HLH)is a rare immune disorder characterized by uncontrolled activation of cytotoxic T lymphocytes(T cells),natural killer cells(NK cells),triggering a cytokine burst,and severe systemic hyperinflammation.1 HLH can be inherited or developed from infection,autoimmune/autoinflammatory disorders,and neoplasms.