BACKGROUND Small intestine disease endangers human health and is not easy to locate and diagnose.AIM To observe the effect of the MS series of small intestine endoscopes on the gastrointestinal tract,the changes in se...BACKGROUND Small intestine disease endangers human health and is not easy to locate and diagnose.AIM To observe the effect of the MS series of small intestine endoscopes on the gastrointestinal tract,the changes in serum gastrin levels and intestinal tissue,and the time required for the examination.METHODS In vivo experiments in 20 Living pigs were conducted,Bowel preparation was routinely performed,Intravenous anesthesia with propofol and ketamine was applied,the condition of the small intestine was observed and the detection time of the MS series of small intestine endoscopes were recorded,The changes in intestinal tissue using the MS series of small intestine endoscopes observed and compared before and after the examination,Venous blood(3-5 mL)from pigs was collected before and after the experiment;changes in intestinal tissue after use of the MS series of small intestine endoscopes observed after examination.After completion of each type of small intestine endoscope experiment,the pigs were allowed to rest and the next type of small intestine endoscope experiment was performed after 15 days of normal feeding.The detection time data of the single-balloon small intestine endoscope and doubleballoon small intestine endoscope were collected from four hospitals.RESULTS One case of Ascarislumbricoides,one of suspected Crohn’s disease,one small intestinal diverticulum and one anesthesia accident were observed in pigs.The small intestine showed no differences in the MS series of small intestine endoscopes and there were no differences in serum gastrin between the groups(P>0.05).The time required for inspection was recorded,and the overall detection time for the Japanese small intestine endoscopes was approximately 1.68±0.16 h.CONCLUSION Intestinal ascariasis is a common disease in pigs.Some pigs have abnormal intestinal variation.After continuous upgrade and improvement,the MS-3 and MS-4 small intestine endoscope appear superior in terms of detection time.展开更多
The Hong Kong-Zhuhai-Macao （HZM） Bridge is located at the Pearl River estuary and has a total length of 55 km. The HZM Bridge＇s main navigational crossing is by way of two 100 000 m2 artificial islands and a 6.7 km...The Hong Kong-Zhuhai-Macao （HZM） Bridge is located at the Pearl River estuary and has a total length of 55 km. The HZM Bridge＇s main navigational crossing is by way of two 100 000 m2 artificial islands and a 6.7 km long undersea tunnel, which are the link＇s most critical parts.展开更多
What is already known about this topic?Men who have sex with men(MSM)bear a disproportionate burden of new human immunodeficiency virus(HIV)infections and young MSM demonstrate parallel internet-driven HIV incident in...What is already known about this topic?Men who have sex with men(MSM)bear a disproportionate burden of new human immunodeficiency virus(HIV)infections and young MSM demonstrate parallel internet-driven HIV incident infection and dynamic social network.What is added by this report?The HIV positive prevalence and incidence among college MSM were 3.8%and 2.9 per 100 person-years,respectively,while these rates were 13.9%and 10.5 per 100 person-years,respectively,among their social contacts.The overall HIV positive prevalence was 7.2%in Northeast China.HIV-positive MSM have comparatively more social contacts than HIVseronegative MSM.What are the implications for public health practice?Hyper-linkages found in app-based social networks play an important role in HIV transmission via risky sexual behavior and suggest options for online intervention to promote HIV prevention.展开更多
Summary What is already known about this topic?Human immunodeficiency virus(HIV)testing is a critical tool in reducing HIV transmission among men who have sex with men(MSM);young MSM frequently use mobile phone applic...Summary What is already known about this topic?Human immunodeficiency virus(HIV)testing is a critical tool in reducing HIV transmission among men who have sex with men(MSM);young MSM frequently use mobile phone applications and participate in social hook-ups.展开更多
基金Supported by the 2020 Liaoning Provincial Natural Science Foundation General Project,No.2020-MS-332。
文摘BACKGROUND Small intestine disease endangers human health and is not easy to locate and diagnose.AIM To observe the effect of the MS series of small intestine endoscopes on the gastrointestinal tract,the changes in serum gastrin levels and intestinal tissue,and the time required for the examination.METHODS In vivo experiments in 20 Living pigs were conducted,Bowel preparation was routinely performed,Intravenous anesthesia with propofol and ketamine was applied,the condition of the small intestine was observed and the detection time of the MS series of small intestine endoscopes were recorded,The changes in intestinal tissue using the MS series of small intestine endoscopes observed and compared before and after the examination,Venous blood(3-5 mL)from pigs was collected before and after the experiment;changes in intestinal tissue after use of the MS series of small intestine endoscopes observed after examination.After completion of each type of small intestine endoscope experiment,the pigs were allowed to rest and the next type of small intestine endoscope experiment was performed after 15 days of normal feeding.The detection time data of the single-balloon small intestine endoscope and doubleballoon small intestine endoscope were collected from four hospitals.RESULTS One case of Ascarislumbricoides,one of suspected Crohn’s disease,one small intestinal diverticulum and one anesthesia accident were observed in pigs.The small intestine showed no differences in the MS series of small intestine endoscopes and there were no differences in serum gastrin between the groups(P>0.05).The time required for inspection was recorded,and the overall detection time for the Japanese small intestine endoscopes was approximately 1.68±0.16 h.CONCLUSION Intestinal ascariasis is a common disease in pigs.Some pigs have abnormal intestinal variation.After continuous upgrade and improvement,the MS-3 and MS-4 small intestine endoscope appear superior in terms of detection time.
文摘The Hong Kong-Zhuhai-Macao （HZM） Bridge is located at the Pearl River estuary and has a total length of 55 km. The HZM Bridge＇s main navigational crossing is by way of two 100 000 m2 artificial islands and a 6.7 km long undersea tunnel, which are the link＇s most critical parts.
基金supported in part by National Natural Science Foundation of China(72061137007,81673232)Dr.Vermund supported in part by NIH grant number P30MH062294.
文摘What is already known about this topic?Men who have sex with men(MSM)bear a disproportionate burden of new human immunodeficiency virus(HIV)infections and young MSM demonstrate parallel internet-driven HIV incident infection and dynamic social network.What is added by this report?The HIV positive prevalence and incidence among college MSM were 3.8%and 2.9 per 100 person-years,respectively,while these rates were 13.9%and 10.5 per 100 person-years,respectively,among their social contacts.The overall HIV positive prevalence was 7.2%in Northeast China.HIV-positive MSM have comparatively more social contacts than HIVseronegative MSM.What are the implications for public health practice?Hyper-linkages found in app-based social networks play an important role in HIV transmission via risky sexual behavior and suggest options for online intervention to promote HIV prevention.
基金National Natural Science Foundation of China(72061137007,81673232)NIH grant number P30MH062294.
文摘Summary What is already known about this topic?Human immunodeficiency virus(HIV)testing is a critical tool in reducing HIV transmission among men who have sex with men(MSM);young MSM frequently use mobile phone applications and participate in social hook-ups.
