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Relationship between the use of smart medical services and mental health status
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作者 Elif Sarac 《World Journal of Psychiatry》 SCIE 2025年第1期21-25,共5页
In this editorial,I comment on the article by Zhang et al.To emphasize the importance of the topic,I discuss the relationship between the use of smart medical devices and mental health.Smart medical services have the ... In this editorial,I comment on the article by Zhang et al.To emphasize the importance of the topic,I discuss the relationship between the use of smart medical devices and mental health.Smart medical services have the potential to positively influence mental health by providing monitoring,insights,and inter-ventions.However,they also come with challenges that need to be addressed.Understanding the primary purpose for which individuals use these smart tech-nologies is essential to tailoring them to specific mental health needs and prefe-rences. 展开更多
关键词 Smart devices Medical service USAGE PEOPLE RELATIONSHIP Mental health status
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Assessing healthcare workers’knowledge and confidence in the diagnosis,management and prevention of Monkeypox
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作者 Epipode Ntawuyamara Thierry Ingabire +3 位作者 Innocent Yandemye Polycarpe Ndayikeza Bina Bhandari Yan-Hua Liang 《World Journal of Clinical Cases》 SCIE 2025年第1期38-47,共10页
BACKGROUND Monkeypox(Mpox),is a disease of global public health concern,as it does not affect only countries in western and central Africa.AIM To assess Burundi healthcare workers(HCWs)s’level of knowledge and confid... BACKGROUND Monkeypox(Mpox),is a disease of global public health concern,as it does not affect only countries in western and central Africa.AIM To assess Burundi healthcare workers(HCWs)s’level of knowledge and confidence in the diagnosis and management of Mpox.METHODS We conducted a cross-sectional study via an online survey designed mainly from the World Health Organization course distributed among Burundi HCWs from June-July 2023.The questionnaire comprises 8 socioprofessional-related questions,22 questions about Mpox disease knowledge,and 3 questions to assess confidence in Mpox diagnosis and management.The data were analyzed via SPSS software version 25.0.A P value<0.05 was considered to indicate statistical significance.RESULTS The study sample comprised 471 HCWs who were mainly medical doctors(63.9%)and nurses(30.1%).None of the 22 questions concerning Mpox knowledge had at least 50%correct responses.A very low number of HCWs(17.4%)knew that Mpox has a vaccine.The confidence level to diagnose(21.20%),treat(18.00%)or prevent(23.30%)Mpox was low among HCWs.The confidence level in the diagnosis of Mpox was associated with the HCWs’age(P value=0.009),sex(P value<0.001),work experience(P value=0.002),and residence(P value<0.001).The confidence level to treat Mpox was significantly associated with the HCWs’age(P value=0.050),sex(P value<0.001),education(P value=0.033)and occupation(P value=0.005).The confidence level to prevent Mpox was associated with the HCWs’education(P value<0.001),work experience(P value=0.002),residence(P value<0.001)and type of work institution(P value=0.003).CONCLUSION This study revealed that HCWs have the lowest level of knowledge regarding Mpox and a lack of confidence in the ability to diagnose,treat or prevent it.There is an urgent need to organize continuing medical education programs on Mpox epidemiology and preparedness for Burundi HCWs.We encourage future researchers to assess potential hesitancy toward Mpox vaccination and its associated factors. 展开更多
关键词 MONKEYPOX Public health emergency of international concern Healthcare workers EPIDEMIC PREPAREDNESS KNOWLEDGE CONFIDENCE
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Future anxiety and belongingness in young and older adults:An empirical study
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作者 Elif Sarac Esra Yıldız 《World Journal of Psychiatry》 2025年第6期210-219,共10页
BACKGROUND Human beings,by nature,have many expectations that create a feeling of anxiety about the future,but they are endured and long-ranged.They expect to have relationships with others and need to perceive an emo... BACKGROUND Human beings,by nature,have many expectations that create a feeling of anxiety about the future,but they are endured and long-ranged.They expect to have relationships with others and need to perceive an emotional interest,an interpersonal bond,and sustainment to continue living.Perceiving this link is required for feelings of belongingness,which decreases future anxiety.AIM To investigate the future anxiety and belongingness of young and older adults and determine their relationships.METHODS The study was conducted with 404 volunteer participants.Data were collected using the demographic characteristics from the“Dark Future Scale”and“General Belongingness Scale”.RESULTS The mean age of older adults was 66.76±3.74,while that of younger adults was 36.72±10.12.The average score for“future anxiety”was 18.81±7.59,and for“general belongingness",it was 63.31±1.40.Findings indicated a reverse correlation between future anxiety and belongingness.A significant difference in belonging scores was observed between young and older adults(P=0.016,which is<0.05),whereas no significant difference was found regarding future anxiety scores(P>0.05).CONCLUSION Participants had a moderate level of“future anxiety”and higher“belongingness”.Lower belongingness scores correlated with increased future anxiety.Older adults reported a lower sense of belonging than younger individuals. 展开更多
关键词 Future anxiety BELONGINGNESS Older adults Youngers Mental well-being
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Gender-based economic violence and the exploitation of women:A deep dive
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作者 Elif Sarac Deniz Odabas 《World Journal of Psychiatry》 2025年第3期58-65,共8页
Economic violence is a form of domestic violence that extends beyond physical harm,affecting victims’economic stability and independence.This situation perpetuates gender inequality and also reinforces the cycle of g... Economic violence is a form of domestic violence that extends beyond physical harm,affecting victims’economic stability and independence.This situation perpetuates gender inequality and also reinforces the cycle of gender-based violence.With definitions of economic violence broadening to encompass a range of coercive and manipulative behaviors-from financial abuse in domestic violence scenarios to the economic harassment faced by stay-at-home moms-understanding this form of exploitation is crucial for crafting effective interventions.This article aims to delve into various facets of economic violence,including its definition,prevalence,and the stark realities it creates for its victims.Following the search of international databases:Social Work Abstracts(EBSCO),Psychology Abstracts,Family and Women Studies Worldwide,Psychiatry Online,Psych INFO(including Psych ARTICLES),PubMed,Wiley,and Scopus,60 peer-reviewed articles that met all inclusion criteria were included in the paper.Our review clarifies that looking forward,the call for a comprehensive understanding of economic violence,enhanced legal frameworks,and the strengthening of supportive networks underscore the multidisciplinary approach required to combat this issue effectively. 展开更多
关键词 Gender based Domestic violence Economic violence EXPLOITATION WOMEN
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Validity of the Arabic version of AAOS-foot and ankle outcomes questionnaire in patients with traumatic foot and ankle injuries
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作者 Sulaiman A AlMousa Mohammad M Alzahrani +3 位作者 Bandar A Alzahrani Ahmed K Alsenan Abdulraheem A Altalib Hashem Abdulkarim Alkhamis 《World Journal of Orthopedics》 2025年第4期36-42,共7页
BACKGROUND Arabic-speaking patients are underrepresented in orthopedic clinical studies,particularly in foot and ankle trauma research.The lack of validated Arabic language tools hinders their inclusion,creating a nee... BACKGROUND Arabic-speaking patients are underrepresented in orthopedic clinical studies,particularly in foot and ankle trauma research.The lack of validated Arabic language tools hinders their inclusion,creating a need for culturally and linguistically adapted instruments.The American Academy of Orthopedic Surgeons Foot and Ankle Outcomes Questionnaire(AAOS-FAOQ)is a widely used tool but has not been adapted for Arabic-speaking patients.AIM To translate,cross-culturally adapt,and validate the AAOS-FAOQ for Arabicspeaking patients with traumatic foot and ankle injuries.METHODS The cross-cultural adaptation followed established guidelines,involving forward and backward translations,expert review,and pre-testing.The final Arabic version was administered alongside the Arabic Short-Form 36(SF-36)to 100 patients for validity testing.Reliability was assessed through test-retest methods with 20 patients completing the questionnaire twice within 48 hours.Pearson correlation coefficients measured convergent and divergent validity with SF-36 subscales,while Cronbach's alpha and intraclass correlation coefficients(ICC)determined internal consistency and reliability.RESULTS Out of 100 patients,92 completed the first set of questionnaires.The Arabic AAOS-FAOQ showed strong correlations with the SF-36 subscales,particularly in physical function and bodily pain(r>0.6).Test-retest reliability was robust,with ICCs of 0.69 and 0.66 for the Global Foot and Ankle Scale and Shoe Comfort Scale,respectively.Cronbach's alpha for internal consistency ranged from 0.7 to 0.9.CONCLUSION The Arabic version of the AAOS-FAOQ demonstrated validity and reliability for use in Arabic-speaking patients with traumatic foot and ankle injuries.This adaptation will enhance the inclusion of this population in orthopedic clinical studies,improving the generalizability of research findings and patient care. 展开更多
关键词 Arabic version American Academy of Orthopedic Foot and Ankle Outcomes ORTHOPEDIC Trauma
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Stratigraphic Revision of the Selendi,Güre,and Uşak Neogene Basins,Western Anatolia
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作者 Fikret GÖKTAŞ Serdar MAYDA Mehmet Cihat ALÇİÇEK 《Acta Geologica Sinica(English Edition)》 2025年第2期332-351,共20页
In a re-examination of the Neogene stratigraphy of the Uşak,Güre,and Selendi basins of western Anatolia,western Turkey,the stratigraphic position of the previously definedİnay Group is revised,which was previousl... In a re-examination of the Neogene stratigraphy of the Uşak,Güre,and Selendi basins of western Anatolia,western Turkey,the stratigraphic position of the previously definedİnay Group is revised,which was previously considered to be of the Middle Miocene age.Based on mammalian biochronology and stratigraphic relationships,two sequences are identified,separated by conformable/transitional contacts within the former group:the Middle Miocene Güre Group is composed of the FakılıFormation,characterized by alluvial fan deposits,and the lacustrine Derbent Formation.Radiometric dating of alkaline volcanics laterally associated with Güre Group sediments in the Uşak and Güre basins,and mammalian fossils re-evaluated into the MN5-6 biozones in the Selendi Basin,indicate early Middle Miocene.Considering the stratigraphic relationship with the overlying early Late Mioceneİnay Group as redefined,we estimate that the Güre Group was deposited in the Middle Miocene.Theİnay Group is characterized by a lateral-vertical transition from alluvial deposits of the Ahmetler Formation to the overlying lacustrine Ulubey Formation.An MN9-10 fauna,containing deinotheres,was found within the latter formation. 展开更多
关键词 stratigraphy mammalian biochronology Miocene basins Vallesian Western Anatolia Türkiye
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Evaluation of the Measles Epidemiological Surveillance System in the Kangaba Health District in 2022
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作者 Ousmane Sy Ahmadou Boly +4 位作者 Modibo Dabo Moussa Sougane Fanta Niare Aliou Bagayoko Akory Ag Iknane 《Open Journal of Epidemiology》 2025年第1期117-127,共11页
Introduction: The WHO’s measles control strategy is based on epidemiological surveillance and vaccination. Little is currently known about the performance of the surveillance system, particularly in outlying areas. I... Introduction: The WHO’s measles control strategy is based on epidemiological surveillance and vaccination. Little is currently known about the performance of the surveillance system, particularly in outlying areas. It is in this context that the present study was carried out to evaluate the measles epidemiological surveillance system in the Kangaba health district. Method: This was a descriptive cross-sectional study with retrospective data collection for the period from 1 January to 31 December 2022 in the Kangaba health district with 18 epidemiological surveillance officers. Data were collected using an observation grid and documentary analysis. Results: We found a simplicity of 97%, a representativeness of 95% and a reactivity of 53%. Not all notified cases were sampled (64%). Of the 17 CSCom, 8 were positive. A total of 34 confirmed cases of measles were recorded, with one death. Conclusion: Overall, the system is functional and well-established in the health centres, but it remains important to ensure that suspected cases are investigated and that the time between sampling and the availability of laboratory results is respected. 展开更多
关键词 EVALUATION Epidemiological Surveillance MEASLES Kangaba
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Abrasive wear behavior of functionally graded Al_(3)Ti reinforced aluminum matrix composite
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作者 Eylül Tuğçe Yaman Yildiz Ömer Savaş +1 位作者 Muhammed Soner Başer Engin Kocaman 《China Foundry》 2025年第1期45-54,共10页
Aluminum alloys are widely used in industry due to their light weight.These alloys are generally exposed to abrasive wear,which diminishes their effective lifespan.The wear resistance of these alloys is enhanced by ad... Aluminum alloys are widely used in industry due to their light weight.These alloys are generally exposed to abrasive wear,which diminishes their effective lifespan.The wear resistance of these alloys is enhanced by adding various reinforcements,however,this enhancement comes at the cost of reduced fracture toughness.This paradox of increased wear resistance versus decreased fracture toughness in aluminum alloys can be resolved by using functionally graded materials (FGMs).This study focuses on the abrasive wear behavior of functional graded aluminum matrix composites reinforced with Al_(3)Ti particles.The wear properties of the composites were investigated by considering the characteristics of the composite such as matrix type and various composite zones,as well as the wear parameters such as abrasive particle diameter,load,sliding speed and distance.Taguchi method was used in the abrasive wear tests in order to get more reliable results in a timeefficient manner.Experiment recipes were created based on the L_(27)(3^(6)) orthogonal series.As a result of the study,it is observed that the wear resistance of the composites increases with an increase in Al_(3)Ti reinforcement content and hardness of the matrix.In addition,the size of abrasive particles and the applied load are significant factors affecting abrasive wear. 展开更多
关键词 functionally graded Al_(3)Ti Taguchi abrasive wear
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The Land Use in Turkey: A General Assessment and Affecting Factors 被引量:1
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作者 A. Ahmet Yücer 《Journal of Geoscience and Environment Protection》 2020年第10期102-116,共15页
Discussions related to land use in Turkey in recent years has been increasing. These discussions are mostly between those who want to protect the natural environment and those who demand other sectoral investment area... Discussions related to land use in Turkey in recent years has been increasing. These discussions are mostly between those who want to protect the natural environment and those who demand other sectoral investment areas. However, there has not been a comprehensive and holistic study assessment of the land use, except for local studies. For this reason, the present study has been conducted in order to reveal the change in land use in the country’s geography. In order to achieve the aims of the study, the literature was reviewed, institutional data were compiled, and the results of previous local studies were evaluated using appropriate methods. Factors affecting land use were examined in the study and it was seen from the findings that significant land use changes occurred in the last 75 years. Although land use suitable for natural structure was common in advance, after the 1980s sectoral needs came to the fore. With the accelerated urbanization and industrialization, tourism, mining and dam areas have become widespread. It has been determined that there is a need for new scientific studies on land use, revision of ineffective laws, and national land use plans that take into account the sectoral needs in order to reduce the discussions. 展开更多
关键词 Land Use Natural Structure LEGISLATION POPULATION MECHANIZATION
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Impact of parenting styles on preschoolers’behaviors 被引量:1
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作者 Elif Sarac 《World Journal of Clinical Cases》 SCIE 2024年第23期5294-5298,共5页
In this editorial,I comment on the article“Association of preschool children behavior and emotional problems with the parenting behavior of both parents”which was published in the latest issue of“World Journal of C... In this editorial,I comment on the article“Association of preschool children behavior and emotional problems with the parenting behavior of both parents”which was published in the latest issue of“World Journal of Clinical Cases”that demonstrates the prevalence of behavioral disorders in preschool children.Therefore I am focused on parenting which is the most effective factor shown to affect the development and continuity of these behaviors.The management of child behavior problems is crucial.Children in early ages,especially preschoolers who are in the first 5 years of life,are influenced by dramatic changes in various aspects of development,such as social,emotional,and physical.Also,children experience many changes linked to different developmental tasks,such as discovering themselves,getting new friendships,and adapting to a new environment.In this period,parents have a critical role in supporting child development.If parents do not manage and overcome their child’s misbehavior,it could be transformed into psychosocial problems in adulthood.Parenting is the most powerful predictor in the social development of preschool children.Several studies have shown that to reduce the child’s emotional and behavioral problems,a warm relationship between parents and children is needed.In addition,recent studies have demonstrated significant relationships between family regulation factors and parenting,as well as with child behaviors. 展开更多
关键词 Behavioral problems CHILDREN Emotional problems Parenting style PRESCHOOL
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Comparative analysis of pulmonary and extrapulmonary tuberculosis:A seven-year experience from a refugee host country,Turkiye 被引量:1
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作者 Tulay Unver Ulusoy Filiz Duyar Agca +4 位作者 Hacer Demirköse Hanife Nur Karakoc Parlayan Nilgün Altın Dilek Bulut Irfan Sencan 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2024年第11期508-515,共8页
Objective:To investigate and compare the demographic characteristics,clinical findings,and laboratory results of pulmonary tuberculosis(PTB)and extrapulmonary tuberculosis(EPTB)patients,among Turkish citizens,and fore... Objective:To investigate and compare the demographic characteristics,clinical findings,and laboratory results of pulmonary tuberculosis(PTB)and extrapulmonary tuberculosis(EPTB)patients,among Turkish citizens,and foreign nationals.Methods:This study included patients aged 18 and over,both Turkish citizens and foreign nationals,diagnosed with PTB or EPTB between 2016 and 2022.All patients were divided into PTB and EPTB group,and demographic characteristics,clinical findings,and laboratory results were compared.Patients with both PTB and EPTB were not included in the comparison.Multivariate logistic regression analysis was conducted to identify potential risk factors for PTB.Results:Among the 261 TB cases included,46 patients(17.6%)had PTB,and 188(72%)had EPTB.The percentage of female patients was significantly higher(P=0.003)in EPTB compared to PTB group.While the prevalence of diabetes mellitus(P=0.002),hypertension(P=0.017),coronary obstructive pulmonary disease(P=0.001),congestive heart failure(P=0.005),coronary artery disease(P=0.001)and immunosuppressive medication use(P=0.017)were significantly higher in PTB patients than in EPTB patients.Multivariate logistical analysis reveals that male(OR 2.6,95%CI 1.3-5.5,P=0.009),diabetes mellitus(OR 2.7,95%CI 1.2-6.1,P=0.015),and asthma(OR 6.3,95%CI 1.2-33.9,P=0.032)were associated with an increased risk of PTB.Social security coverage(P<0.001)and regular employment status(P<0.001)were found to be lower and the presence of multidrug resistance(P=0.002),isoniazid resistance(P=0.012),and rifampin resistance(P=0.012)were found to be significantly higher in foreign-national TB patients comparing with Turkiye citizens.Conclusions:Patients with PTB need to be evaluated for comorbidities and PTB should be investigated in men,in patients with diabetes mellitus or asthma if there are clinical findings suspicious for TB.TB screening for foreign nationals upon entry into the country is essential for TB control and elimination. 展开更多
关键词 Pulmonary tuberculosis Extrapulmonary tuberculosis Refugees IMMIGRANTS COMORBIDITIES
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Evaluation of the mental health of COVID-19 patients discharged from the intensive care unit
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作者 Elif Sarac 《World Journal of Clinical Cases》 SCIE 2024年第33期6587-6590,共4页
In this editorial,I address the mental health status of patients who have been discharged from intensive care units(ICUs)after battling coronavirus disease 2019(COVID-19).An ICU admission is generally a stressful expe... In this editorial,I address the mental health status of patients who have been discharged from intensive care units(ICUs)after battling coronavirus disease 2019(COVID-19).An ICU admission is generally a stressful experience,and for severe COVID-19 survivors prolonged treatment in the ICU can lead to significant psychological consequences.These individuals may experience psychiatric distress,including symptoms such as insomnia,anxiety,depression,and even posttraumatic psychological issues.Research indicates that during the first 6 months to 1 year following an ICU stay,nearly one-third of survivors exhibit symptoms similar to those of depression and post-traumatic stress disorder.Several factors may have contributed to the development of depressive and anxious symptoms during the COVID-19 pandemic,particularly for those who underwent an ICU stay.The ICU environment itself is inherently stressful,filled with the constant noise of various medical devices.Studies have provided strong evidence that the prolonged need for ventilation support and the loss of freedom of movement are key factors in the development of psychological problems among COVID-19 patients who had been treated in the ICU. 展开更多
关键词 COVID-19 PATIENT Post-intensive care unit DISCHARGE Mental health
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Assessment of Breast Cancer Prevention Practices among Women Attending Primary Health Care in Abha City, Aseer Region, Saudi Arabia
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作者 Sabah Mohammed Asiri Sultan Yahia Alfifii +6 位作者 Tagreed Khairan Al-Rashidi Sager Misfer Alqahtani Faiz Abdulrahman Alshafa Fayez Mari Alamri Amal Mohammed Asiri Fatima Mohammed Ali Almagadi Thuraya Mohammed Asiri 《International Journal of Clinical Medicine》 CAS 2024年第2期31-54,共24页
Cancer is a leading cause of death worldwide, with breast cancer being the most common (2.26 million new cases and 685,000 deaths). In Saudi Arabia, breast cancer ranked the first among females in 2014, accounting for... Cancer is a leading cause of death worldwide, with breast cancer being the most common (2.26 million new cases and 685,000 deaths). In Saudi Arabia, breast cancer ranked the first among females in 2014, accounting for 15.9% of all cancers reported among Saudi nationals and 28.7% of all cancers reported among females of all ages. Early detection of breast cancer could decrease the risks, have a better prognosis, and have better outcomes/more successful treatments. Prevalence of breast cancer reached more than 25% of all diagnosed cancer in the kingdom among women. Aim: This study aims to assess the knowledge and performance of women attending primary care centers about breast self-examination and mammogram screening for prevention and early detection of breast cancer in Abha city primary healthcare centers, Kingdom of Saudi Arabia. Research Method: cross sectional design was conducted by using questionnaire, which was distributed to primary care center nurses. The collected data was statistically analyzed using the Statistical Package for Social Sciences, version 25. Results: The study found that participants had poor awareness and knowledge about breast self-examination, risk factors for breast cancer, and trends and practices in early diagnosis of breast cancer. Conclusion and Recommendations: It recommends increasing awareness campaigns and providing educational programs to improve knowledge and practices. 展开更多
关键词 ASSESSMENT Breast Cancer Prevention Practices Women Attending Health Care Centers Abha City
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Antibody Titer of Newcastle Disease in Vaccinated and Non-vaccinated Local Chicken of Cambodia
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作者 Sokha Thim Solida Keo +4 位作者 Kannan Dim Kroesna Kang Sath Keo Vutey Venn Kouch Theng 《Journal of Environmental Science and Engineering(B)》 CAS 2024年第2期80-85,共6页
The experiment was conducted at Veterinary Research Station of Faculty of Veterinary Medicine,Royal University of Agriculture.The experimental period lasted 60 days,starting from October 1st to November 30th 2022.CRD(... The experiment was conducted at Veterinary Research Station of Faculty of Veterinary Medicine,Royal University of Agriculture.The experimental period lasted 60 days,starting from October 1st to November 30th 2022.CRD(Completely Randomized Design)was used with 2 treatments/groups,vaccination group and non-vaccination group“control”,and 6 replications.The vaccination groups received two times of vaccination by dropping into the ocular at 7 days and 21 days.Meanwhile,blood samples were collected 3 times to detect the antibody level of ND(Newcastle Disease)and contained 21 days old,35 days old and 49 days old chicks.The ELISA(Enzyme-Linked Immunosorbent Assay)was performed to detect the antibody of those 2 groups.The result of finding showed that the S/P(Sample to Positive)ratio of control at 21 days,was very low,even in 3rd quartile,which was below the threshold.However,the vaccination group was relatively high,even in 1st quartile,which was higher than the threshold.At 35 days,S/P ratio of control group was still very low,but a bit higher than at 21 days.Meanwhile,the vaccination group was still high,even in 1st quartile,and two-time higher than at 21 days,but an increasing number of samples developed less antibody than threshold,accounting for 12.22%.At 49 days,the control group was still very low,even in 3rd quartile,but a bit higher than at 21 days and 35 days,and was close to the threshold.The vaccination group was still relatively high,even in 1st quartile but lower than three times comparing to 35 days.However,in this age,the number of chickens that developed antibody seemed to be increased in the control group,vice versa for vaccination group.The average S/P ratio was different significant(p<0.001),where vaccination had higher S/P ratio than control.It was similar finding for log-titer,the vaccination had higher figure(p<0.001).The risk of infection of ND was higher in control group,but it will reduce by increasing the age of chicken,while vaccination group was decreased by increasing age,especially at 49 days and we need to consider another vaccination to get full protection. 展开更多
关键词 ANTIBODY VACCINATION CONTROL ND S/P ratio
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Insights into the anorexic mechanism of Khat:an integrated in vivo,ex vivo,and in silico investigations
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作者 Ahmed Ali Jerah Manal Mohamed Elhassan Taha +7 位作者 Abdullah Farasani Sivakumar Sivagurunathan Moni Emad Sayed Shaheen Andleeb Khan Ibrahim Abdo Khardali Magbool Oraiby Heyam Mohamed Ali Sidahmed Siddig Ibrahim Abdelwahab 《Traditional Medicine Research》 2024年第10期36-51,共16页
Background:Chewing Khat(Catha edulis)releases cathine and cathinone,which may reduce appetite via an unknown mechanism.This study investigated the peripheral and central effects of fresh leaves and buds of Catha eduli... Background:Chewing Khat(Catha edulis)releases cathine and cathinone,which may reduce appetite via an unknown mechanism.This study investigated the peripheral and central effects of fresh leaves and buds of Catha edulis water extract(CEWE)on appetite biomarkers,gene expression,and body weight,using in vivo,ex vivo,and in silico models.Methods:Rats of both sexes were orally administered CEWE at different doses and durations in three different experiments.Liquid chromatography-mass spectroscopy(LC-MS)-MS was used to detect cathinone and cathine in the murine blood.The effect of Khat on serotonin receptors was studied in isolated rat fundus samples.Docking of the two Khat ligands was performed on G(The 5-hydroxytryptamine-type 2C receptor(5-HT2C)in an agonist-bound active conformation)and H(5-HT2C in an antagonist-bound inactive conformation)proteins to determine which ligands are most likely to act as agonists or antagonists.Results:Significant differences(P<0.05)in body weight were observed between the CEWE-treated groups and the controls over eight weeks.However,the plasma leptin and ghrelin levels did not change significantly(P>0.05).The expression of the ghrelin and leptin genes was also unaffected,but the expression of the 5-hydroxytryptamine(5-HT)gene decreased(P<0.05)with CEWE treatment.CEWE antagonizes 5-HT receptors in isolated rat fundus samples.Docking findings indicated that the khat ligands bound to 5-HT2C receptors.Cathine and cathinone levels in rat plasma were measured.Conclusion:Khat extract may suppress appetite by antagonizing the 5-HT receptors.Further research is required to understand its mechanism and potential applications. 展开更多
关键词 Catha edulis APPETITE LEPTIN GHRELIN 5-HYDROXYTRYPTAMINE molecular docking
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Antimicrobial Resistance of Aeromonas spp.and Vibrio spp.Isolated from Fresh Pangasius Fish in Cambodia
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作者 Duk Seyha Chrun Rithy +5 位作者 Nguon Samnang Sudsai Trevanich Nora Navarro-Gonzalez Ségolène Calvez Chea Rortana Venn Vutey 《Journal of Environmental Science and Engineering(B)》 CAS 2024年第5期199-209,共11页
The study was conducted to identify Aeromonas spp.and Vibrio spp.from fresh Pangasius fish(n=153)in Cambodia and test their antimicrobial susceptibility to antibiotics.The samples were collected from different wet mar... The study was conducted to identify Aeromonas spp.and Vibrio spp.from fresh Pangasius fish(n=153)in Cambodia and test their antimicrobial susceptibility to antibiotics.The samples were collected from different wet markets of Phnom Penh city and Kampong Thom,and Siem Reap provinces.The bacteria were isolated by using selective medium and their AMR(Antimicrobial Resistance)profile was tested by API 20E technique,respectively.Susceptibility profile was determined for seven antibiotics commonly used.The Vibrio spp.(34.64%,n=53)was found to be higher than Aeromonas spp.(24.83%,n=38).Four Vibrio and four Aeromonas species were identified where V.parahaemolyticus(57%,n=30)was the highest,followed by V.cholerae(38%,n=20),V.fluvialis(3.8%,n=2)and V.aglinolyticus(1.9%,n=1),whereas A.hydrophila(47%,n=18)was the highest,followed by A.hydrophila/caviae(45%,n=17),A.sobria(5%,n=2),A.caviae(2.6%,n=1).All the species presented high multi-resistance to the tested antibiotics.The antibiotic susceptibility profile to ampicillin(74%-100%),ciprofloxacin(7%-100%),sulfamethoxazole/trimethoprim(14%-100%),florfenicol(14%-100%),oxytetracycline(7%-100%),erythromycin(10%-100%)and colistin sulphate(33%-100%)was revealed resistance level in Aeromonas spp.whereas few species of Vibrio spp.resistant to ampicillin(43%-100%),ciprofloxacin(14%-100%),sulfamethoxazole/trimethoprim(14%-100%),florfenicol(14%-100%),oxytetracycline(20%-100%),erythromycin(29%-100%),colistin sulphate(33%-100%)were also identified.The results revealed these Aeromonas spp.and Vibrio spp.are potentially reservoirs of antibiotic resistance genes.MDR(Multidrug Resistance)was widespread among the samples isolated.That is a high-risk source of contamination since those pathogens and antimicrobials are often used.Our findings highlight that the aquatic environment and fresh Pangasius fish act as reservoirs of AMR Aeromonas spp.and Vibrio spp.which underline the need for a judicious use of antimicrobials and timely surveillance of AMR in aquaculture.Overall,the findings of our study indicated the presence of A.hydrophila,A.hydrophila/caviae,A.caviae,A.sobria,V.parahaemolyticus,V.cholerae,V.alginolyticus and V.fluvialis and high MDR.This result will allow us to identify the potential risk over circulating isolates in animal health and public health and the spread through the food chain offering supports for appropriate sanitary actions. 展开更多
关键词 Aeromonas spp. Vibrio spp. prevalence MDR AMR and Cambodia’s Pangasius.
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Mitigating effects of various phosphorus sources on arsenic toxicity under anaerobic conditions for rice and aerobic conditions for sunflower and maize plants
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作者 Mehmet BTASKIN Hanife AKCA +5 位作者 Selver KAN Havva TASKIN Saima KBABAR Yusuf KKADIOGLU Kiymet DENIZ Aydin GUNES 《Pedosphere》 CSCD 2024年第6期1146-1157,共12页
Arsenic(As)contamination is one of the major factors that contribute to environmental pollution,and it plays havoc with sustainability of crop production.Nano-hydroxyapatite(nHAP)can be an effective phosphorus(P)sourc... Arsenic(As)contamination is one of the major factors that contribute to environmental pollution,and it plays havoc with sustainability of crop production.Nano-hydroxyapatite(nHAP)can be an effective phosphorus(P)source to cope with As toxicity.The mitigating effects of variable P sources on As toxicity in rice,sunflower,and maize grown in an alkaline soil were evaluated.Arsenic was applied at 0 and 20 mg kg^(-1),and P was applied at 0,50,and 500 mg kg^(-1)in the forms of triple superphosphate(TSP)and nHAP.In addition,the same amount of phosphoric acid was also used in the sunflower and maize experiments with the other P sources.The structural and functional properties of nHAP were determined by Fourier transform infrared spectroscopy,X-ray diffraction,scanning electron microscopy,and energy-dispersive X-ray spectroscopy.Stunted growth was observed in rice,and less in sunflower;maize remained unaffected by As toxicity.In the presence of As,TSP and nHAP at their high doses(500 mg kg^(-1))significantly increased the rice dry weight compared with the control(0 mg kg^(-1)).The As concentration in rice was decreased by approximately 25%in the presence of 50 mg kg^(-1)TSP and 500 mg kg^(-1)nHAP.The P treatments had no significant effect on the As concentration in sunflower,whereas the As concentration in maize was increased by 500 mg kg^(-1)TSP.In the absence and presence of As,nHAP at 50 mg kg^(-1)significantly increased rice P concentration,whereas in the presence of As,500 mg kg^(-1)TSP significantly increased P concentration in rice compared with the control.Arsenic had no significant effect on sunflower P concentration,while the maize P concentration was decreased in the 0 mg kg^(-1)P treatment.It can be concluded that TSP and nHAP were effective in alleviating As toxicity in rice and sunflower.Comparative studies are further needed to determine the long-term effects of TSP and nHAP on prevention of As toxicity in field conditions. 展开更多
关键词 ARSENATE ARSENITE NANO-HYDROXYAPATITE phosphoric acid redox condition triple superphosphate
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Newcastle Disease in Chickens of Smallholder Farmers at Krang Yov Commune S’ang District,Kandal Province
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作者 Sokha Thim Chhay Kheang Lim +3 位作者 Kroesna Kang Sath Keo Vutey Venn Kouch Theng 《Journal of Environmental Science and Engineering(A)》 CAS 2024年第2期68-75,共8页
The study was conducted in Krang Yov commune,S’ang district,Kandal province and was conducted in three villages,including Kampong Po,Andong and Svay Damnak village.In the total,88 families were selected for interview... The study was conducted in Krang Yov commune,S’ang district,Kandal province and was conducted in three villages,including Kampong Po,Andong and Svay Damnak village.In the total,88 families were selected for interview by using snowball technic of nonprobability sampling.According to the results of the interviews,it showed that the number of farmers who raised chickens and had participated in training was very low number,ranging from 10.71%to 34.38%.For chicken raising system,the free ranging was the most popular by allowing the chicken to scavenge around the village,however,the total confinement was also applied.The local breed was more popular and the purpose of raising was for selling meat,however there were few households that raised the fighting cock for hobby.The number of chickens owned per household,was mostly less than 20 birds,while,the average number of birds per household ranged from 16.82 birds to 37.66 birds.However,the average number of birds per household was significant different between the households who have participated in chicken raising training and those who never participated(p<0.05),accounting for 47.52 birds and 19.85 birds,respectively.For the chicken feed,most of the farmers in those three villages used the concentration feed to offer the chicken,especially for supplementation,but,the whole rice was also used to supplement feed.The vaccination for chicken was significant different among the villages(p<0.05),in which the household in Kampong Po village had highest percentage of vaccinating their chicken,40.63%,than those in Svay Damnak and Andong village.The Newcastle vaccination was the more popular in those areas.But,all of the households have experienced with the disease,especially ND(Newcastle Disease)accounting for 67.05%,followed by influenza and fowl pox.When chicken got sick,most of farmers had treated their chicken with different methods,especially buying the medicine from the store and treatment by themselves were mostly applicable.Regarding the specific case of Newcastle disease,most of farmers were familiar with this disease and it frequently occurred in dry season and the knowledge on biosecurity measurement was very high,during suspected cases.However,the real practice with bird infected with Newcastle disease was limited since they treated the affected bird,and few farmers left their affected chicken in the flock,which could cause further spreading of this disease in the flock and village. 展开更多
关键词 Raising system VACCINATION BIOSECURITY ND
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Growth Efficiency of Local Chickens Using Sweet Potato Vine with Concentration Feed as a Basal Diet
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作者 Hieak Hun Suheang Sorn +4 位作者 Chan Bun Manay Ith Ty Chhay Kouch Theng Chetra Sar 《Journal of Environmental Science and Engineering(B)》 CAS 2024年第3期108-113,共6页
The experiment was conducted at the animal experimental station of the Faculty of Animal Sciences,Royal University of Agriculture,commenced from 10 January to 14 March,2022.The CRD(Completely Randomized Design)was use... The experiment was conducted at the animal experimental station of the Faculty of Animal Sciences,Royal University of Agriculture,commenced from 10 January to 14 March,2022.The CRD(Completely Randomized Design)was used with 5 treatments and 4 replications.The 500 chicks at one-day-old,local bread,were purchased from farmers who run their small scale hatchery farm.The chicks were kept together till 21 days old,and then were allocated randomly into in five diets(treatments),25 chicks per replication.The feed formulas for this study were designed and calculated to maintain a protein content of approximately 17%,dividing into 5 feed formulas(Treatments),such as concentrated feed only(control treatment:T0),plus 10%of fresh sweet potato vine(T1),plus 20%of fresh sweet potato vine(T2),plus 30%of fresh sweet potato vine(T3)and plus 20%of sweet potato vine meal(T4).The results showed that the treatment T1,had a similar final weight with the treatment T4,but was slightly lower than the treatment T0 which used concentrated feed alone.Feed intake and FCR(Feed Conversion Ratio)were not significantly different among those treatments.In conclusion,the average daily weight gain of chickens seemed to decrease with increasing the level of fresh sweet potato vine.Thus,the optimum level of fresh sweet potato vine was 10%,which may have little effect on the growth performance of local chickens.In addition,it was not far different from the positive control treatment and the treatment using sweet potato vine meal.However,the producers can increase the amount of sweet potato vine in feed formula by processing it into meal and mixing with concentrated feed or using as feed ingredients. 展开更多
关键词 Local breed final weight feed intake FCR
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Cattle Production and Lumpy Skin Disease of Smallholder Farmers in Svay Rieng Province
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作者 Kimeang Chay Tola Ka +2 位作者 Sokun Khoeun Chann Bun Kouch Theng 《Journal of Environmental Science and Engineering(B)》 2024年第1期39-46,共8页
The cattle production in Romeas Haek district,Svay Rieng province,was developed remarkably,since there were some households raising cattle in large number,more than 20 heads.The grazing method of cattle was tethering ... The cattle production in Romeas Haek district,Svay Rieng province,was developed remarkably,since there were some households raising cattle in large number,more than 20 heads.The grazing method of cattle was tethering and free grassing in the commune grass,since the natural grass and rice straw were the main source of cattle feed,however some of them supplemented their cattle with crop-byproducts,planting grass or concentrated feed.For the majority,BCS(Body Condition Scoring)of the cattle in those areas was 3 accounting for 52%-73.33%,but it was found the thin cattle has low BCS of 2 accounting for 11.11%to 40.00%and also fat cattle has BCS of 4 up to 27.78%.However,the average BCS varied with village which ranged from 2.68 to 3.17,but is not different in term of commune and sex of cattle.Besides facing with shortage of feed,the experience with diseases was also another concern,since 85.71%to 95.83%of the households faced this problem last year.Among the clinical signs found,lumpy skin was 100%,i.e.no one escaped from this problem,thus making them aware of vaccinating their cattle against some diseases such as FMD(Foot and Mouth Disease),HS(Hemorrhagic Septicemia)and LSD(Lumpy Skin Disease),but mostly vaccination was used against FMD.Because the LSD has occurred in these areas since 2020,then the seroprevalence was found in high positive up to 72.62%by Enzyme-Linked Immunosorbent Assay(ELISA)test.This positive rate was also varying by villages,ranging from 53.3%to 94.44%.But there was no association between positive cattle with commune,BCS,sex and age of cattle.In conclusion,the cattle production in Romeas Haek district,Svay Rieng province had developed markedly,however the shortage of feed and disease occurrence are the main challenges for farmer cattle producers,especially LSD outbreak last year.However,most of the farmers have been aware of the benefit of vaccination and had vaccinated their cattle against those main disease,such as FMD,HS and LSD. 展开更多
关键词 Cattle production lumpy skin smallholder farmers seroprevalance
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