Arecent study published in Nature Immunology by Sheedy et al.1 indicates that uptake of modified low-den- sity lipoprotein （LDL） by the scavenger receptor CD36 primes and activates the NLRP3 inflammasome, providing ...Arecent study published in Nature Immunology by Sheedy et al.1 indicates that uptake of modified low-den- sity lipoprotein （LDL） by the scavenger receptor CD36 primes and activates the NLRP3 inflammasome, providing an early pathogenic pathway that links cho- lesterol accumulation to the chronic inflammatory process of atherosclero- sis.1 Atherosclerosis arises from chronic vascular inflammation elicited by lipids.展开更多
文摘Arecent study published in Nature Immunology by Sheedy et al.1 indicates that uptake of modified low-den- sity lipoprotein （LDL） by the scavenger receptor CD36 primes and activates the NLRP3 inflammasome, providing an early pathogenic pathway that links cho- lesterol accumulation to the chronic inflammatory process of atherosclero- sis.1 Atherosclerosis arises from chronic vascular inflammation elicited by lipids.
