In recent years,train-tail swaying of 160 km/h electric multiple units(EMUs)inside single-line tunnels has been heavily researched,because the issue needs to be solved urgently.In this paper,a co-simulation model of v...In recent years,train-tail swaying of 160 km/h electric multiple units(EMUs)inside single-line tunnels has been heavily researched,because the issue needs to be solved urgently.In this paper,a co-simulation model of vortex-induced vibration(VIV)of the tail car body is established,and the aerodynamics of train-tail swaying is studied.The simulation results were confirmed through a field test of operating EMUs.Furthermore,the influence mechanism of train-tail swaying on the wake flow field is studied in detail through a wind-tunnel experiment and a simulation of a reduced-scaled train model.The results demonstrate that the aerodynamic force frequency(i.e.,vortex-induced frequency)of the train tail increases linearly with train speed.When the train runs at 130 km/h,with a small amplitude of train-tail swaying(within 10 mm),the vortex-induced frequency is 1.7 Hz,which primarily depends on the nose shape of the train tail.After the tail car body nose is extended,the vortex-induced frequency is decreased.As the swaying amplitude of the train tail increases(exceeding 25 mm),the separation point of the high-intensity vortex in the train wake shifts downstream to the nose tip,and the vortex-induced frequency shifts from 1.7 Hz to the nearby car body hunting(i.e.,the primary hunting)frequency of 1.3 Hz,which leads to the frequency-locking phenomenon of VIV,and the resonance intensifies train-tail swaying.For the motor vehicle of the train tail,optimization of the yaw damper to improve its primary hunting stability can effectively alleviate train-tail swaying inside single-line tunnels.Optimization of the tail car body nose shape reduces the amplitude of the vortex-induced force,thereby weakening the aerodynamic effect and solving the problem of train-tail swaying inside the single-line tunnels.展开更多
In recent years,with the increasing frequency of global Marine activities,the occurrence probability of Marine accidents and emergencies has also increased.As a new technical means,small unmanned aerial vehicles(UAVs)...In recent years,with the increasing frequency of global Marine activities,the occurrence probability of Marine accidents and emergencies has also increased.As a new technical means,small unmanned aerial vehicles(UAVs)have shown great application potential in Marine search and rescue activities.In Marine search and rescue activities,small UAVs can quickly arrive at the scene of the accident and carry out efficient information collection and monitoring under its simple and flexible operation.Compared with traditional search and rescue methods,small UAVs can cover a wider area,provide more detailed and accurate on-site information,provide strong support for search and rescue decision-making,and thus improve the quality and efficiency of maritime rescue.In this regard,this paper first describes the application advantages of small UAVs in Marine search and rescue activities and then puts forward effective application paths,to provide some references for relevant researchers.展开更多
Cooperative search-attack is an important application of unmanned aerial vehicle(UAV)swarm in military field.The coupling between path planning and task allocation,the heterogeneity of UAVs,and the dynamic nature of t...Cooperative search-attack is an important application of unmanned aerial vehicle(UAV)swarm in military field.The coupling between path planning and task allocation,the heterogeneity of UAVs,and the dynamic nature of task environment greatly increase the complexity and difficulty of the UAV swarm cooperative search-attack mission planning problem.Inspired by the collaborative hunting behavior of wolf pack,a distributed selforganizing method for UAV swarm search-attack mission planning is proposed.First,to solve the multi-target search problem in unknown environments,a wolf scouting behavior-inspired cooperative search algorithm for UAV swarm is designed.Second,a distributed self-organizing task allocation algorithm for UAV swarm cooperative attacking of targets is proposed by analyzing the flexible labor division behavior of wolves.By abstracting the UAV as a simple artificial wolf agent,the flexible motion planning and group task coordinating for UAV swarm can be realized by self-organizing.The effectiveness of the proposed method is verified by a set of simulation experiments,the stability and scalability are evaluated,and the integrated solution for the coupled path planning and task allocation problems for the UAV swarm cooperative search-attack task can be well performed.展开更多
Soybean (Glycine max (L.) Merrill) is a salt-sensitive crop,and its production is severely affected by saline soils.Therefore,the response of soybean seeds to salt stress during germination was investigated at both ph...Soybean (Glycine max (L.) Merrill) is a salt-sensitive crop,and its production is severely affected by saline soils.Therefore,the response of soybean seeds to salt stress during germination was investigated at both physiological and proteomic levels.The salt-tolerant cultivar Lee68 and salt-sensitive cultivar N2899 were exposed to 100 mmol/L NaCl until radicle protrusion from the seed coat.In both cultivars,the final germination percentage was not affected by salt,but the mean germination times of Lee68 and N2899 were delayed by 0.3 and 1.0 d,respectively,compared with controls.In response to salt stress,the abscisic acid content increased,and gibberellic acid (GA1+3) and isopentenyladenosine decreased.Indole-3-acetic acid increased in Lee68,but remained unchanged in N2899.The proteins extracted from germinated seeds were separated using two-dimensional gel electrophoresis (2-DE),followed by Coomassie brilliant blue G-250 staining.About 350 protein spots from 2-DE gels of pH range 3 to 10 and 650 spots from gels of pH range 4 to 7 were reproducibly resolved,of which 18 protein spots showed changes in abundance as a result of salt stress in both cultivars.After matrix-assisted laser desorption ionization-time of flight-mass spectroscopy (MALDI-TOF-MS) analysis of the differentially expressed proteins,the peptide mass fingerprint was searched against the soybean UniGene database and nine proteins were successfully identified.Ferritin and 20S proteasome subunit β-6 were up-regulated in both cultivars.Glyceraldehyde 3-phosphate dehydrogenase,glutathione S-transferase (GST) 9,GST 10,and seed maturation protein PM36 were down-regulated in Lee68 by salt,but still remained at a certain level.However,these proteins were present in lower levels in control N2899 and were up-regulated under salt stress.The results indicate that these proteins might have important roles in defense mechanisms against salt stress during soybean seed germination.展开更多
In this paper, we introduce several new subclasses of the function class Σ of bi-univalent functions analytic in the open unit disc defined by convolution.Furthermore, we investigate the bounds of the coefficients |a...In this paper, we introduce several new subclasses of the function class Σ of bi-univalent functions analytic in the open unit disc defined by convolution.Furthermore, we investigate the bounds of the coefficients |a2| and |a3| for functions in these new subclasses. The results presented in this paper improve or generalize the recent works of other authors.展开更多
Among most traditional piezo water cooling systems, piezoelectric valve pumps are adopted as their driving sources. The valves in these pumps induce problems of shock and vibration and also make their structure compli...Among most traditional piezo water cooling systems, piezoelectric valve pumps are adopted as their driving sources. The valves in these pumps induce problems of shock and vibration and also make their structure complicated, which is uneasy to minimize and reduce their reliability and applicability of the whole system. In order to avoid these problems caused by valve structure, a novel valveless piezoelectric pump is developed, which integrates both functions of transforming and cooling. The pump’s Y-shape tree-like construction not only increases the efficiency of cooling but also the system reliability and applicability. Firstly, a multistage Y-shape treelike bifurcate tube is proposed, then a valveless piezoelectric pump with multistage Y-shape treelike bifurcate tubes is designed and its working principle is analyzed. Then, the theoretical analysis of flow resistance characteristics and the flow rate of the valveless piezoelectric pump are performed. Meanwhile, commercial software CFX is employed to perform the numerical simulation for the pump. Finally, this valveless piezoelectric pump is fabricated, the relationship between the flow rates and driving frequency, as well as the relationship between the back pressure and the driving frequency are experimentally investigated. The experimental results show that the maximum flow rate is 35.6 mL/min under 100 V peak-to-peak voltage (10.3 Hz) power supply, and the maximum back pressure is 55 mm H2O under 100 V (9 Hz) power supply, which validates the feasibility of the valveless piezoelectric pump with multistage Y-shape treelike bifurcate tubes. The proposed research provides certain references for the design of valveless piezoelectric pump and improves the reliability of piezo water cooling systems.展开更多
Hearing loss is the most common sensorineural disorder worldwide and is associated with more than1000 mutations in more than 90 genes. While mutations in genes such as GJB2(gap-junction protein β 2)and GJB6(gap-junct...Hearing loss is the most common sensorineural disorder worldwide and is associated with more than1000 mutations in more than 90 genes. While mutations in genes such as GJB2(gap-junction protein β 2)and GJB6(gap-junction protein β 6) are highly prevalent in Caucasian, Asian, and Middle Eastern populations, they are rare in both native African populations and those of African descent. The objective of this paper is to review the current knowledge regarding the epidemiology and genetics of hearing loss in African populations with a focus on native sub-Saharan African populations. Environmental etiologies related to poor access to healthcare and perinatal care account for the majority of cases. Syndromic etiologies including Waardenburg, Pendred and Usher syndromes are uncommon causes of hearing loss in these populations. Of the non-syndromic causes, common mutations in GJB2 and GJB6 are rarely implicated in populations of African descent. Recent use of next-generation sequencing(NGS) has identified several candidate deafness genes in African populations from Nigeria and South Africa that are unique when compared to common causative mutations worldwide. Researchers also recently described a dominant mutation in MYO3α in an African American family with non-syndromic hearing loss. The use of NGS and specialized panels will aid in identifying rare and novel mutations in a more cost-and timeeffective manner. The identification of common hearing loss mutations in indigenous African populations will pave the way for translation into genetic deafness research in populations of African descent worldwide.展开更多
Forty-six XX disorder of sex development is an uncommon medical condition observed at times during the evaluation of a man＇s fertility. The following is a case series and literature review of phenotypically normal me...Forty-six XX disorder of sex development is an uncommon medical condition observed at times during the evaluation of a man＇s fertility. The following is a case series and literature review of phenotypically normal men diagnosed with this karyotype. Our goal is to comprehend the patients＇ clinical presentation as well as their laboratory results aiming to explore options available for their management. A formal literature review through PubMed and MEDLINE databases was performed using ＂46 XX man＂ as a word search. A total of 55 patients, including those conveyed in this article were diagnosed with a 46 XX karyotype during their fertility evaluation. The patients＇ mean age _＋ s.d. was 34 ＋ 10 years and their mean height ＋ s.d. was 166 ＋ 6.5 cm. Overall, they presented with hypergonadotropic hypogonadism. Sexual dysfunction, reduced hair distribution, and gynecomastia were reported in 20% （4120）, 25.8% （8/31）, and 42% （13131） of the patients, respectively. The SRYgene was detected in 36 （83.7%） and was absent in the remaining seven （16.3%） patients. We found that a multidisciplinary approach to management is preferred in 46 XX patients. Screening for remnants of the mullerian ducts and for malignant transformation in dysgenetic gonads is imperative. Hypogonadism should be addressed, while fertility options are in vitro fertilization with donor sperm or adoption.展开更多
The Fekete-Szego inequality for a subclass H(α,λ,A,B) of the class H of normalized analytic functions is studied.For each f(z)=z+~∞∑_(n=2)αnz^n ∈ H(α,λ,A,B),the sharp upper bounds of |α_3-α_2~2|for any compl...The Fekete-Szego inequality for a subclass H(α,λ,A,B) of the class H of normalized analytic functions is studied.For each f(z)=z+~∞∑_(n=2)αnz^n ∈ H(α,λ,A,B),the sharp upper bounds of |α_3-α_2~2|for any complex parameter u are obtained by using the fundamental inequalities of analytic functions and analytical techniques and the applications of the inequality of functions defined with Hadaniard product are proved.展开更多
Denote S to be the class of functions which are analytic,normalized and univalent in the open unit disk U={z:|z|<1}.The important subclasses of S are the class of starlike and convex functions,which we denote by S ...Denote S to be the class of functions which are analytic,normalized and univalent in the open unit disk U={z:|z|<1}.The important subclasses of S are the class of starlike and convex functions,which we denote by S and C.In this paper,we obtain the third Hankel determinant for the inverse of functions f(z)=z+∞Σn=2 anz^n belonging to S^*and C.展开更多
The fluorescence properties of reduced nicotinamide adenine dinucleotide(NADH)and oxidizedflavoproteins(Fp)including flavin adenine dinucleotide(FAD)in the respiratory chain are sensitive indicators of intracellular m...The fluorescence properties of reduced nicotinamide adenine dinucleotide(NADH)and oxidizedflavoproteins(Fp)including flavin adenine dinucleotide(FAD)in the respiratory chain are sensitive indicators of intracellular metabolic states and have been applied to the studies of mitochondrial function with energy-linked processes.The redox scanner,a three-dimensional(3D)low temperature imager previously developed by Chance et al.,measures the in vivo metabolicproperties of tissue samples by acquiring fluorescence images of NADH and Fp.The redox ratios,i.e.Fp/(Fp+NADH)and NADH/(Fp+NADH),provided a sensitive index of the mitochondrialredox state and were determined based on relative signal intensity ratios.Here we report thefurther development of the redox scanning technique by using a calibration method to quantifythe nominal concentration of the fluorophores in tissues.The redox scanner exhibited very goodlinear response in the range of NADH concentration between 165–1318µM and Fp between90–720µM using snap-frozen solution standards.Tissue samples such as human tumor mousexenografts and various mouse organs were redox-scanned together with adjacent NADH and Fpstandards of known concentration at liquid nitrogen temperature.The nominal NADH and Fpconcentrations as well as the redox ratios in the tissue samples were quantified by normalizing the tissue NADH and Fp fluorescence signal to that of the snap-frozen solution standards.This calibration procedure allows comparing redox images obtained at different time,independent of instrument settings.The quantitative multi-slice redox images revealed heterogeneity inmitochondrial redox state in the tissues.展开更多
Let Hn(p)be the class of functions of the form f(z)=z p+ +∞Σ k=n akzk+p,which are analytic in the open unit disk U={z:|z|<1}.In the paper,we introduce a new subclass Bn(μ,a,c,α,p;φ)of Hn(p)and investigate its ...Let Hn(p)be the class of functions of the form f(z)=z p+ +∞Σ k=n akzk+p,which are analytic in the open unit disk U={z:|z|<1}.In the paper,we introduce a new subclass Bn(μ,a,c,α,p;φ)of Hn(p)and investigate its subordination relations,inclusion relations and distortion theorems.The results obtained include the related results of some authors as their special case.展开更多
Mitochondrial redox states provide important information about energy-linked biological processes and signaling events in tissues for various disease phenotypes including cancer.The redox scanning method developed at ...Mitochondrial redox states provide important information about energy-linked biological processes and signaling events in tissues for various disease phenotypes including cancer.The redox scanning method developed at the Chance laboratory about 30 years ago has allowed 3D highresolution(∼50×50×10µm^(3))imaging of mitochondrial redox state in tissue on the basis of the fluorescence of NADH(reduced nicotinamide adenine dinucleotide)and Fp(oxidized flavoproteins including flavin adenine dinucleotide,i.e.,FAD).In this review,we illustrate its basic principles,recent technical developments,and biomedical applications to cancer diagnostic and therapeutic studies in small animal models.Recently developed calibration procedures for the redox imaging using reference standards allow quantification of nominal NADH and Fp concentrations,and the concentration-based redox ratios,e.g.,Fp/(Fp+NADH)and NADH/(Fp+NADH)in tissues.This calibration facilitates the comparison of redox imaging results acquired for different metabolic states at different times and/or with different instrumental settings.A redox imager using a CCD detector has been developed to acquire 3D images faster and with a higher in-plane resolution down to 10µm.Ex vivo imaging and in vivo imaging of tissue mitochondrial redox status have been demonstrated with the CCD imager.Applications of tissue redox imaging in small animal cancer models include metabolic imaging of glioma and myc-induced mouse mammary tumors,predicting the metastatic potentials of human melanoma and breast cancer mouse xenografts,differentiating precancerous and normal tissues,and monitoring the tumor treatment response to photodynamic therapy.Possible future directions for the development of redox imaging are also discussed.展开更多
The aim of this paper is to establish the Fekete-Szego inequality for a subclass of bi-univalent strongly quasi-starlike functions which is defined in the open unit disk. Furthermore, the coefficients a2 and a3 for fu...The aim of this paper is to establish the Fekete-Szego inequality for a subclass of bi-univalent strongly quasi-starlike functions which is defined in the open unit disk. Furthermore, the coefficients a2 and a3 for functions in this new subclass are estimated.展开更多
The interfacial transition zone (ITZ) between the aggregates and the bulk paste is the weakest zone of ordinary concrete, which largely determines its mechanical and transporting properties. However, a complete unders...The interfacial transition zone (ITZ) between the aggregates and the bulk paste is the weakest zone of ordinary concrete, which largely determines its mechanical and transporting properties. However, a complete understanding and a quantitative modeling of ITZ are still lacking. Consequently, an integrated modeling and experimental study were conducted. First, the theoretical calculation model of the ITZ volume fraction about the rotary ellipsoidal aggregate particles was established based on the nearest surface function formula. Its calculation programs were written based on Visual Basic 6.0 language and achieved visualization and functionalization. Then, the influencing factors of ITZ volume fraction of the ellipsoidal aggregate particles and the overlapping degree between the ITZ were systematically analyzed. Finally, the calculation models of ITZ volume fraction on actual ellipsoidal aggregate were given, based on cobblestones or pebbles particles with naturally ellipsoidal shape. The results indicate that the calculation model proposed is highly reliable.展开更多
This paper first introduces the concepts of mobile operators and mobile sequence, with which it redefines the rate of particle swarm optimization algorithm and the formula of position updating. Combining this discrete...This paper first introduces the concepts of mobile operators and mobile sequence, with which it redefines the rate of particle swarm optimization algorithm and the formula of position updating. Combining this discrete PSO algorithm with neighbors, the paper puts forward Hybrd Particle Swarm Optimization Algorithm, whose effectiveness is verified at the end of this paper.展开更多
In this paper, we investigate the coefficient estimates of a class of m-fold bi-univalent function de?ned by subordination. The results presented in this paper improve or generalize the recent works of other authors.
In this paper, we introduce a new subclass of bi-univalent functions defined by quasi-subordination and Hohlov operator and obtain the coefficient estimates and Fekete-Szego inequality for function in this new subclas...In this paper, we introduce a new subclass of bi-univalent functions defined by quasi-subordination and Hohlov operator and obtain the coefficient estimates and Fekete-Szego inequality for function in this new subclass. The results presented in this paper improve or generalize the recent works of other authors.展开更多
Let S_s*be the class of normalized functions f defined in the open unit■such that the quantity zf’(z)/f(z)lies in an eight-shaped region in the right-half plane and satisfies the condition■.In this paper,we aim to ...Let S_s*be the class of normalized functions f defined in the open unit■such that the quantity zf’(z)/f(z)lies in an eight-shaped region in the right-half plane and satisfies the condition■.In this paper,we aim to investigate Toeplitz determinants for the inverse of this function classes S_s*associated with sine function.展开更多
To investigate the transport characteristics of chloride ions in cement-based materials, the Mori-Tanaka (M-T) prediction scheme of the effective diffusion coefficient in composites containing single-phase and multi-p...To investigate the transport characteristics of chloride ions in cement-based materials, the Mori-Tanaka (M-T) prediction scheme of the effective diffusion coefficient in composites containing single-phase and multi-phase inclusions is systematically deduced based on the theory of composite mechanics and porous medium. The volume fraction, morphology and distribution of aggregates, as well as the interfacial transition zone (ITZ) are fully taken into consideration in this proposed model. The results show that the algorithm of M-T prediction scheme with high accuracy is relatively simple.展开更多
基金supported by the National Natural Science Foundation of China(Nos.52372403 and U2268211)the Natural Science Foundation of Sichuan Province(No.2022NSFSC0034),China+1 种基金the National Railway Group Science and Technology Program(No.2023J071)the Traction Power State Key Laboratory of the Independent Research and Development Projects(No.2022TPL-T02),China.
文摘In recent years,train-tail swaying of 160 km/h electric multiple units(EMUs)inside single-line tunnels has been heavily researched,because the issue needs to be solved urgently.In this paper,a co-simulation model of vortex-induced vibration(VIV)of the tail car body is established,and the aerodynamics of train-tail swaying is studied.The simulation results were confirmed through a field test of operating EMUs.Furthermore,the influence mechanism of train-tail swaying on the wake flow field is studied in detail through a wind-tunnel experiment and a simulation of a reduced-scaled train model.The results demonstrate that the aerodynamic force frequency(i.e.,vortex-induced frequency)of the train tail increases linearly with train speed.When the train runs at 130 km/h,with a small amplitude of train-tail swaying(within 10 mm),the vortex-induced frequency is 1.7 Hz,which primarily depends on the nose shape of the train tail.After the tail car body nose is extended,the vortex-induced frequency is decreased.As the swaying amplitude of the train tail increases(exceeding 25 mm),the separation point of the high-intensity vortex in the train wake shifts downstream to the nose tip,and the vortex-induced frequency shifts from 1.7 Hz to the nearby car body hunting(i.e.,the primary hunting)frequency of 1.3 Hz,which leads to the frequency-locking phenomenon of VIV,and the resonance intensifies train-tail swaying.For the motor vehicle of the train tail,optimization of the yaw damper to improve its primary hunting stability can effectively alleviate train-tail swaying inside single-line tunnels.Optimization of the tail car body nose shape reduces the amplitude of the vortex-induced force,thereby weakening the aerodynamic effect and solving the problem of train-tail swaying inside the single-line tunnels.
文摘In recent years,with the increasing frequency of global Marine activities,the occurrence probability of Marine accidents and emergencies has also increased.As a new technical means,small unmanned aerial vehicles(UAVs)have shown great application potential in Marine search and rescue activities.In Marine search and rescue activities,small UAVs can quickly arrive at the scene of the accident and carry out efficient information collection and monitoring under its simple and flexible operation.Compared with traditional search and rescue methods,small UAVs can cover a wider area,provide more detailed and accurate on-site information,provide strong support for search and rescue decision-making,and thus improve the quality and efficiency of maritime rescue.In this regard,this paper first describes the application advantages of small UAVs in Marine search and rescue activities and then puts forward effective application paths,to provide some references for relevant researchers.
基金supported by the National Natural Science Foundation of China(61502534)the Shaanxi Provincial Natural Science Foundation(2020JQ-493)+2 种基金the Integrative Equipment Research Project of Armed Police Force(WJ20211A030018)the Military Science Project of the National Social Science Fund(WJ2019-SKJJ-C-092)the Theoretical Research Foundation of Armed Police Engineering University(WJY202148)。
文摘Cooperative search-attack is an important application of unmanned aerial vehicle(UAV)swarm in military field.The coupling between path planning and task allocation,the heterogeneity of UAVs,and the dynamic nature of task environment greatly increase the complexity and difficulty of the UAV swarm cooperative search-attack mission planning problem.Inspired by the collaborative hunting behavior of wolf pack,a distributed selforganizing method for UAV swarm search-attack mission planning is proposed.First,to solve the multi-target search problem in unknown environments,a wolf scouting behavior-inspired cooperative search algorithm for UAV swarm is designed.Second,a distributed self-organizing task allocation algorithm for UAV swarm cooperative attacking of targets is proposed by analyzing the flexible labor division behavior of wolves.By abstracting the UAV as a simple artificial wolf agent,the flexible motion planning and group task coordinating for UAV swarm can be realized by self-organizing.The effectiveness of the proposed method is verified by a set of simulation experiments,the stability and scalability are evaluated,and the integrated solution for the coupled path planning and task allocation problems for the UAV swarm cooperative search-attack task can be well performed.
基金Project supported by the National Natural Science Foundation of China (No. 30800692)the National Basic Research Program (973) of China (Nos. 2010CB125906 and 2009CB118400)the National High-Tech R & D Program (863) of China (No. 2006AA10Z1C1)
文摘Soybean (Glycine max (L.) Merrill) is a salt-sensitive crop,and its production is severely affected by saline soils.Therefore,the response of soybean seeds to salt stress during germination was investigated at both physiological and proteomic levels.The salt-tolerant cultivar Lee68 and salt-sensitive cultivar N2899 were exposed to 100 mmol/L NaCl until radicle protrusion from the seed coat.In both cultivars,the final germination percentage was not affected by salt,but the mean germination times of Lee68 and N2899 were delayed by 0.3 and 1.0 d,respectively,compared with controls.In response to salt stress,the abscisic acid content increased,and gibberellic acid (GA1+3) and isopentenyladenosine decreased.Indole-3-acetic acid increased in Lee68,but remained unchanged in N2899.The proteins extracted from germinated seeds were separated using two-dimensional gel electrophoresis (2-DE),followed by Coomassie brilliant blue G-250 staining.About 350 protein spots from 2-DE gels of pH range 3 to 10 and 650 spots from gels of pH range 4 to 7 were reproducibly resolved,of which 18 protein spots showed changes in abundance as a result of salt stress in both cultivars.After matrix-assisted laser desorption ionization-time of flight-mass spectroscopy (MALDI-TOF-MS) analysis of the differentially expressed proteins,the peptide mass fingerprint was searched against the soybean UniGene database and nine proteins were successfully identified.Ferritin and 20S proteasome subunit β-6 were up-regulated in both cultivars.Glyceraldehyde 3-phosphate dehydrogenase,glutathione S-transferase (GST) 9,GST 10,and seed maturation protein PM36 were down-regulated in Lee68 by salt,but still remained at a certain level.However,these proteins were present in lower levels in control N2899 and were up-regulated under salt stress.The results indicate that these proteins might have important roles in defense mechanisms against salt stress during soybean seed germination.
基金The NSF(KJ2015A372) of Anhui Provincial Department of Education
文摘In this paper, we introduce several new subclasses of the function class Σ of bi-univalent functions analytic in the open unit disc defined by convolution.Furthermore, we investigate the bounds of the coefficients |a2| and |a3| for functions in these new subclasses. The results presented in this paper improve or generalize the recent works of other authors.
基金supported by National Natural Science Foundation of China (Grant Nos. 50775109, 50735002, 51075201)Open Fund of State Key Lab of Digital Manufacturing Equipment and Technology of Huazhong University of Science and Technology of China (Grant No.DMETKF2009002)
文摘Among most traditional piezo water cooling systems, piezoelectric valve pumps are adopted as their driving sources. The valves in these pumps induce problems of shock and vibration and also make their structure complicated, which is uneasy to minimize and reduce their reliability and applicability of the whole system. In order to avoid these problems caused by valve structure, a novel valveless piezoelectric pump is developed, which integrates both functions of transforming and cooling. The pump’s Y-shape tree-like construction not only increases the efficiency of cooling but also the system reliability and applicability. Firstly, a multistage Y-shape treelike bifurcate tube is proposed, then a valveless piezoelectric pump with multistage Y-shape treelike bifurcate tubes is designed and its working principle is analyzed. Then, the theoretical analysis of flow resistance characteristics and the flow rate of the valveless piezoelectric pump are performed. Meanwhile, commercial software CFX is employed to perform the numerical simulation for the pump. Finally, this valveless piezoelectric pump is fabricated, the relationship between the flow rates and driving frequency, as well as the relationship between the back pressure and the driving frequency are experimentally investigated. The experimental results show that the maximum flow rate is 35.6 mL/min under 100 V peak-to-peak voltage (10.3 Hz) power supply, and the maximum back pressure is 55 mm H2O under 100 V (9 Hz) power supply, which validates the feasibility of the valveless piezoelectric pump with multistage Y-shape treelike bifurcate tubes. The proposed research provides certain references for the design of valveless piezoelectric pump and improves the reliability of piezo water cooling systems.
基金supported by grants from the National Institutes of Health/National Institute on Deafness and Other Communication Disorders to Xuezhong Liu (R01 DC05575,R01 DC01246,2P50DC000422-Sub-Project 6432,and R01 DC012115)the University of Pretoria RDP grant and the South African ENT Society Research Grant to RI Kabahuma
文摘Hearing loss is the most common sensorineural disorder worldwide and is associated with more than1000 mutations in more than 90 genes. While mutations in genes such as GJB2(gap-junction protein β 2)and GJB6(gap-junction protein β 6) are highly prevalent in Caucasian, Asian, and Middle Eastern populations, they are rare in both native African populations and those of African descent. The objective of this paper is to review the current knowledge regarding the epidemiology and genetics of hearing loss in African populations with a focus on native sub-Saharan African populations. Environmental etiologies related to poor access to healthcare and perinatal care account for the majority of cases. Syndromic etiologies including Waardenburg, Pendred and Usher syndromes are uncommon causes of hearing loss in these populations. Of the non-syndromic causes, common mutations in GJB2 and GJB6 are rarely implicated in populations of African descent. Recent use of next-generation sequencing(NGS) has identified several candidate deafness genes in African populations from Nigeria and South Africa that are unique when compared to common causative mutations worldwide. Researchers also recently described a dominant mutation in MYO3α in an African American family with non-syndromic hearing loss. The use of NGS and specialized panels will aid in identifying rare and novel mutations in a more cost-and timeeffective manner. The identification of common hearing loss mutations in indigenous African populations will pave the way for translation into genetic deafness research in populations of African descent worldwide.
文摘Forty-six XX disorder of sex development is an uncommon medical condition observed at times during the evaluation of a man＇s fertility. The following is a case series and literature review of phenotypically normal men diagnosed with this karyotype. Our goal is to comprehend the patients＇ clinical presentation as well as their laboratory results aiming to explore options available for their management. A formal literature review through PubMed and MEDLINE databases was performed using ＂46 XX man＂ as a word search. A total of 55 patients, including those conveyed in this article were diagnosed with a 46 XX karyotype during their fertility evaluation. The patients＇ mean age _＋ s.d. was 34 ＋ 10 years and their mean height ＋ s.d. was 166 ＋ 6.5 cm. Overall, they presented with hypergonadotropic hypogonadism. Sexual dysfunction, reduced hair distribution, and gynecomastia were reported in 20% （4120）, 25.8% （8/31）, and 42% （13131） of the patients, respectively. The SRYgene was detected in 36 （83.7%） and was absent in the remaining seven （16.3%） patients. We found that a multidisciplinary approach to management is preferred in 46 XX patients. Screening for remnants of the mullerian ducts and for malignant transformation in dysgenetic gonads is imperative. Hypogonadism should be addressed, while fertility options are in vitro fertilization with donor sperm or adoption.
基金Supported by the Natural Science Foundation of Department of Education of Anhui Province（KJ2015A372）
文摘The Fekete-Szego inequality for a subclass H(α,λ,A,B) of the class H of normalized analytic functions is studied.For each f(z)=z+~∞∑_(n=2)αnz^n ∈ H(α,λ,A,B),the sharp upper bounds of |α_3-α_2~2|for any complex parameter u are obtained by using the fundamental inequalities of analytic functions and analytical techniques and the applications of the inequality of functions defined with Hadaniard product are proved.
基金The NSF(11561001)of Chinathe NSF(2014MS0101)of Inner Mongolia Province+1 种基金the Higher School Foundation(NJZY19211)of Inner Mongolia of Chinathe NSF(KJ2018A0839,KJ2018A0833)of Anhui Provincial Department of Education
文摘Denote S to be the class of functions which are analytic,normalized and univalent in the open unit disk U={z:|z|<1}.The important subclasses of S are the class of starlike and convex functions,which we denote by S and C.In this paper,we obtain the third Hankel determinant for the inverse of functions f(z)=z+∞Σn=2 anz^n belonging to S^*and C.
基金the Susan G.Komen Foundation Grant KG081069(PI:L.Z.Li)an NIH supported research resource(P41-RR02305,PI:R.Reddy)+1 种基金the Network of Translational Research in Optical Imaging(NTROI)at the University of Pennsylvania(U54 CA105008,PI:W.S.El-Deiry)an NIH Grant UO1-CA105490(PI:L.A.Chodosh).
文摘The fluorescence properties of reduced nicotinamide adenine dinucleotide(NADH)and oxidizedflavoproteins(Fp)including flavin adenine dinucleotide(FAD)in the respiratory chain are sensitive indicators of intracellular metabolic states and have been applied to the studies of mitochondrial function with energy-linked processes.The redox scanner,a three-dimensional(3D)low temperature imager previously developed by Chance et al.,measures the in vivo metabolicproperties of tissue samples by acquiring fluorescence images of NADH and Fp.The redox ratios,i.e.Fp/(Fp+NADH)and NADH/(Fp+NADH),provided a sensitive index of the mitochondrialredox state and were determined based on relative signal intensity ratios.Here we report thefurther development of the redox scanning technique by using a calibration method to quantifythe nominal concentration of the fluorophores in tissues.The redox scanner exhibited very goodlinear response in the range of NADH concentration between 165–1318µM and Fp between90–720µM using snap-frozen solution standards.Tissue samples such as human tumor mousexenografts and various mouse organs were redox-scanned together with adjacent NADH and Fpstandards of known concentration at liquid nitrogen temperature.The nominal NADH and Fpconcentrations as well as the redox ratios in the tissue samples were quantified by normalizing the tissue NADH and Fp fluorescence signal to that of the snap-frozen solution standards.This calibration procedure allows comparing redox images obtained at different time,independent of instrument settings.The quantitative multi-slice redox images revealed heterogeneity inmitochondrial redox state in the tissues.
基金Supported by the Doctoral Foundation of the Education Committee of China(20050574002)
文摘Let Hn(p)be the class of functions of the form f(z)=z p+ +∞Σ k=n akzk+p,which are analytic in the open unit disk U={z:|z|<1}.In the paper,we introduce a new subclass Bn(μ,a,c,α,p;φ)of Hn(p)and investigate its subordination relations,inclusion relations and distortion theorems.The results obtained include the related results of some authors as their special case.
基金the Susan G.Komen Foundation Grant KG081069(PI:L.Z.Li)The Center for Magnietic Resonance and Optical Imaging,and an NIH supported research resource(P41-RR02305,PI:R.Reddy).
文摘Mitochondrial redox states provide important information about energy-linked biological processes and signaling events in tissues for various disease phenotypes including cancer.The redox scanning method developed at the Chance laboratory about 30 years ago has allowed 3D highresolution(∼50×50×10µm^(3))imaging of mitochondrial redox state in tissue on the basis of the fluorescence of NADH(reduced nicotinamide adenine dinucleotide)and Fp(oxidized flavoproteins including flavin adenine dinucleotide,i.e.,FAD).In this review,we illustrate its basic principles,recent technical developments,and biomedical applications to cancer diagnostic and therapeutic studies in small animal models.Recently developed calibration procedures for the redox imaging using reference standards allow quantification of nominal NADH and Fp concentrations,and the concentration-based redox ratios,e.g.,Fp/(Fp+NADH)and NADH/(Fp+NADH)in tissues.This calibration facilitates the comparison of redox imaging results acquired for different metabolic states at different times and/or with different instrumental settings.A redox imager using a CCD detector has been developed to acquire 3D images faster and with a higher in-plane resolution down to 10µm.Ex vivo imaging and in vivo imaging of tissue mitochondrial redox status have been demonstrated with the CCD imager.Applications of tissue redox imaging in small animal cancer models include metabolic imaging of glioma and myc-induced mouse mammary tumors,predicting the metastatic potentials of human melanoma and breast cancer mouse xenografts,differentiating precancerous and normal tissues,and monitoring the tumor treatment response to photodynamic therapy.Possible future directions for the development of redox imaging are also discussed.
基金The NSF(KJ2018A0833)of Anhui Provincial Department of Educationthe Scientific Research Foundation(17X0413)of Guangzhou Civil Aviation College
文摘The aim of this paper is to establish the Fekete-Szego inequality for a subclass of bi-univalent strongly quasi-starlike functions which is defined in the open unit disk. Furthermore, the coefficients a2 and a3 for functions in this new subclass are estimated.
基金Funded by the National Natural Science Foundations of China(Nos.51478278 and 51408380)the Natural Science Foundation of Hebei Province(No.E2014210149)Higher Education Science and Technology Research Project of Hebei Province(No.ZD2016065)
文摘The interfacial transition zone (ITZ) between the aggregates and the bulk paste is the weakest zone of ordinary concrete, which largely determines its mechanical and transporting properties. However, a complete understanding and a quantitative modeling of ITZ are still lacking. Consequently, an integrated modeling and experimental study were conducted. First, the theoretical calculation model of the ITZ volume fraction about the rotary ellipsoidal aggregate particles was established based on the nearest surface function formula. Its calculation programs were written based on Visual Basic 6.0 language and achieved visualization and functionalization. Then, the influencing factors of ITZ volume fraction of the ellipsoidal aggregate particles and the overlapping degree between the ITZ were systematically analyzed. Finally, the calculation models of ITZ volume fraction on actual ellipsoidal aggregate were given, based on cobblestones or pebbles particles with naturally ellipsoidal shape. The results indicate that the calculation model proposed is highly reliable.
文摘This paper first introduces the concepts of mobile operators and mobile sequence, with which it redefines the rate of particle swarm optimization algorithm and the formula of position updating. Combining this discrete PSO algorithm with neighbors, the paper puts forward Hybrd Particle Swarm Optimization Algorithm, whose effectiveness is verified at the end of this paper.
基金The NSF(KJ2018A0839,KJ2018A0833) of Anhui Provincial Department of Education
文摘In this paper, we investigate the coefficient estimates of a class of m-fold bi-univalent function de?ned by subordination. The results presented in this paper improve or generalize the recent works of other authors.
基金The NSF(11561001)of Chinathe NSF(2014MS0101)of Inner Mongolia Province+1 种基金the Higher School Foundation(NJZY19211)of Inner Mongolia of Chinathe NSF(KJ2018A0839,KJ2018A0833)of Anhui Provincial Department of Education
文摘In this paper, we introduce a new subclass of bi-univalent functions defined by quasi-subordination and Hohlov operator and obtain the coefficient estimates and Fekete-Szego inequality for function in this new subclass. The results presented in this paper improve or generalize the recent works of other authors.
基金Supported by the National Natural Science Foundation of China(Grant No.11561001)the Program for Young Talents of Science and Technology in Universities of Inner Mongolia Autonomous Region(Grant No.NJYT-18-A14)+4 种基金the Natural Science Foundation of Inner Mongolia of China(Grant No.2018MS01026)the Higher School Foundation of Inner Mongolia of China(Grant No.NJZY19211)the Natural Science Foundation of Anhui Provincial Department of Education(Grant No.KJ2018A0833)Provincial Quality Engineering Project of Anhui Colleges and Universities(Grant No.2018mooc608)the Key Cultivated Project at School Level of the National Science Fund of Guangzhou Civil Aviation College(Grant Nos.18X0428,18X0433)。
文摘Let S_s*be the class of normalized functions f defined in the open unit■such that the quantity zf’(z)/f(z)lies in an eight-shaped region in the right-half plane and satisfies the condition■.In this paper,we aim to investigate Toeplitz determinants for the inverse of this function classes S_s*associated with sine function.
基金Funded by the National Natural Science Foundations of China(Nos.51778378,51478278)。
文摘To investigate the transport characteristics of chloride ions in cement-based materials, the Mori-Tanaka (M-T) prediction scheme of the effective diffusion coefficient in composites containing single-phase and multi-phase inclusions is systematically deduced based on the theory of composite mechanics and porous medium. The volume fraction, morphology and distribution of aggregates, as well as the interfacial transition zone (ITZ) are fully taken into consideration in this proposed model. The results show that the algorithm of M-T prediction scheme with high accuracy is relatively simple.
