1.Objective The Eastern Junggar Kalamaili region in Xinjiang constitutes a significant tin metallogenic belt in northwest China(Fig.1a).It hosts four independent tin deposits-Kamusite,Ganliangzi,Beilekuduke,and Saresh...1.Objective The Eastern Junggar Kalamaili region in Xinjiang constitutes a significant tin metallogenic belt in northwest China(Fig.1a).It hosts four independent tin deposits-Kamusite,Ganliangzi,Beilekuduke,and Sareshenke-from west to east,supplemented by two tin mineralized points,namely Hongtujingzi and Sujiquan(Figs.1b).according to the ore type and the composition of gangue minerals,the tin deposits in the region are classified into two groups:Quartz vein type and greisen type,with the Sareshenke deposit ascribed to the former and the remainder to the latter.展开更多
This study examines the intricate occurrences of thermal and solutal Marangoni convection in three-layered flows of viscous fluids,with a particular emphasis on their relevance to renewable energy systems.This researc...This study examines the intricate occurrences of thermal and solutal Marangoni convection in three-layered flows of viscous fluids,with a particular emphasis on their relevance to renewable energy systems.This research examines the flow of a three-layered viscous fluid,considering the combined influence of heat and solutal buoyancy driven Rayleigh-Bénard convection,as well as thermal and solutal Marangoni convection.The homotopy perturbation method is used to examine and simulate complex fluid flow and transport phenomena,providing important understanding of the fundamental physics and assisting in the optimization of various battery configurations.The inquiry examines the primary elements that influence Marangoni convection and its impact on battery performance,providing insights on possible enhancements in energy storage devices.The findings indicate that the velocity profiles shown graphically exhibit a prominent core zone characterized by the maximum speed,which progressively decreases as it approaches the walls of the channel.This study enhances our comprehension of fluid dynamics and the transmission of heat and mass in intricate systems,which has substantial ramifications for the advancement of sustainable energy solutions.展开更多
Existing conventional megajoule plasma focus machines with 2–3 MA are producing fusion neutron yields of several times 10^(11) in deuterium operation,the fusion yields predominantly being the beam-gas target.Increasi...Existing conventional megajoule plasma focus machines with 2–3 MA are producing fusion neutron yields of several times 10^(11) in deuterium operation,the fusion yields predominantly being the beam-gas target.Increasing the current to 10 MA and using 50%–50%D-T mixture will scale the neutron yield towards 10^(16) D-T fusion neutrons.In this work,we derive the Lawson criterion for plasma focus devices with a beam-target fusion neutron mechanism,so that we may glimpse what future technological advancements are needed for a break-even Q=1 plasma focus.We perform numerical experiments with a present-day feasible 0.9 MV,8.1 MJ,11 MA machine operating in 100 Torr in 50%–50%D-T mixture.The Lee Code simulation gives a detailed description of the plasma focus dynamics through each phase,and provides plasma and yield parameters which show that out of 1.1×10^(19) fast beam ions produced in the plasma focus pinch,only 1.24×10^(14) ions take part in beam-target fusion reactions within the pinch,producing the same number of D-T neutrons.The remnant beam ions,numbering at least 10^(19),exit the focus pinch at 1.9 MeV,which is far above the 115 keV ion energy necessary for an optimum beam-target cross-section.We propose to regain the lost fusion rates by using a high-pressure D-T-filled drift-tube to attenuate the energy of the remnant beam ions until they reach the energy for the optimum fusion cross-section.Such a fusion enhancement tube would further harvest beam-target fusion reactions by increasing the interaction path length(1 m)at increased interaction density(6 atm).A gain factor of 300 is conservatively estimated,with a final yield of 3.7×10^(16) D-T neutrons carrying kinetic energy of 83.6 kJ,demonstrating Q=0.01.展开更多
Dear Editor,Severe fever with thrombocytopenia syndrome(SFTS)is an emerging tick-borne infectious disease caused by a novel bunyavirus called SFTS virus(SFTSV).It was initially identified in China in 2009(Yu et al.,20...Dear Editor,Severe fever with thrombocytopenia syndrome(SFTS)is an emerging tick-borne infectious disease caused by a novel bunyavirus called SFTS virus(SFTSV).It was initially identified in China in 2009(Yu et al.,2011).Since then,the number of reported SFTS cases has rapidly increased in China,South Korea,and Japan(Li,et al.,2018;Takahashi et al.,2014;Kim et al.,2018).Sporadic SFTS cases have also been identified in several other Asian countries,such as Vietnam,Pakistan,Myanmar,and Thailand(Takahashi et al.,2014;Tran et al.,2019;Li et al.,2021).This disease is recognized as a highly lethal viral hemorrhagic fever with a mortality rate ranging from 12%to 50%(Yu et al.,2011;Li et al.,2018;Takahashi et al.,2014;Kim et al.,2013).SFTS primarily spreads to humans through bites from ticks infected with SFTSV,with the Haemaphysalis longicornis tick acting as the predominant vector for SFTSV(Zhuang et al.,2018).展开更多
0 INTRODUCTION Sedimentary exhalative(SEDEX)lead-zinc deposit was traditionally considered as a result of submarine hydrothermal exhalation,including exhalative plume and brine pool models(Izanloo et al.,2022;Spinks e...0 INTRODUCTION Sedimentary exhalative(SEDEX)lead-zinc deposit was traditionally considered as a result of submarine hydrothermal exhalation,including exhalative plume and brine pool models(Izanloo et al.,2022;Spinks et al.,2021;Maghfouri et al.,2020;Sangster,2020,2018;Huang et al.,2019;Rajabi et al.,2015;Goodfellow and Lydon,2007;Large et al.,2005,2001;Peng et al.,2000;Goodfellow et al.,1993;Figures 1a,1b).However,recognition of mineralization as subseafloor hydrothermal replacement in a few SEDEX deposits has challenged the traditional consideration(Magnall et al.,2023,2021,2020a,b;Hayward et al.,2021;Figure 1c).Researchers come to believe that subseafloor replacement rather than submarine exhalation is a dominant process for SEDEX mineralization,but this needs to be examined through more case studies.展开更多
This paper is devoted to the investigation of the Landau–Ginzburg–Higgs equation(LGHe),which serves as a mathematical model to understand phenomena such as superconductivity and cyclotron waves.The LGHe finds applic...This paper is devoted to the investigation of the Landau–Ginzburg–Higgs equation(LGHe),which serves as a mathematical model to understand phenomena such as superconductivity and cyclotron waves.The LGHe finds applications in various scientific fields,including fluid dynamics,plasma physics,biological systems,and electricity-electronics.The study adopts Lie symmetry analysis as the primary framework for exploration.This analysis involves the identification of Lie point symmetries that are admitted by the differential equation.By leveraging these Lie point symmetries,symmetry reductions are performed,leading to the discovery of group invariant solutions.To obtain explicit solutions,several mathematical methods are applied,including Kudryashov's method,the extended Jacobi elliptic function expansion method,the power series method,and the simplest equation method.These methods yield solutions characterized by exponential,hyperbolic,and elliptic functions.The obtained solutions are visually represented through 3D,2D,and density plots,which effectively illustrate the nature of the solutions.These plots depict various patterns,such as kink-shaped,singular kink-shaped,bell-shaped,and periodic solutions.Finally,the paper employs the multiplier method and the conservation theorem introduced by Ibragimov to derive conserved vectors.These conserved vectors play a crucial role in the study of physical quantities,such as the conservation of energy and momentum,and contribute to the understanding of the underlying physics of the system.展开更多
Directed x-rays produced in the interaction of sub-picosecond laser pulses of moderate relativistic intensity with plasma of near-critical density are investigated. Synchrotron-like (betatron) radiation occurs in the ...Directed x-rays produced in the interaction of sub-picosecond laser pulses of moderate relativistic intensity with plasma of near-critical density are investigated. Synchrotron-like (betatron) radiation occurs in the process of direct laser acceleration (DLA) of electrons in a relativisticlaser channel when the electrons undergo transverse betatron oscillations in self-generated quasi-static electric and magnetic fields. In anexperiment at the PHELIX laser system, high-current directed beams of DLA electrons with a mean energy ten times higher than the ponderomotive potential and maximum energy up to 100 MeV were measured at 10^(19) W/cm^(2)laser intensity. The spectrum of directed x-raysin the range of 5–60 keV was evaluated using two sets of Ross filters placed at 0°and 10°to the laser pulse propagation axis. The differential x-ray absorption method allowed for absolute measurements of the angular-dependent photon fluence. We report 10^(13) photons/sr withenergies >5 keV measured at 0°to the laser axis and a brilliance of 10^(21) photons s^(−1) mm^(−2) mrad−2(0.1%BW)−1. The angular distributionof the emission has an FWHM of 14°–16°. Thanks to the ultra-high photon fluence, point-like radiation source, and ultra-short emissiontime, DLA-based keV backlighters are promising for various applications in high-energy-density research with kilojoule petawatt-class laserfacilities.展开更多
Introduction:Parkinson’s disease(PD)is the most common neurodegenerative movement disorder.The pathological hallmark is the progressive loss of dopaminergic neurons of the substantia nigra pars compacta,which is acco...Introduction:Parkinson’s disease(PD)is the most common neurodegenerative movement disorder.The pathological hallmark is the progressive loss of dopaminergic neurons of the substantia nigra pars compacta,which is accompanied by widespread alterations in the structu re and function of distributed brain networks.Togethe r,these processes cause a variety of motor symptoms such as bradykinesia,rigidity,tremor,gait disorders,or difficulties in fine motor control(Bange et al.,2022).展开更多
In this paper,we propose a doping approach to lower the error floor of Low-Density Parity-Check(LDPC)codes.The doping component is a short block code in which the information bits are selected from the coded bits of t...In this paper,we propose a doping approach to lower the error floor of Low-Density Parity-Check(LDPC)codes.The doping component is a short block code in which the information bits are selected from the coded bits of the dominant trapping sets of the LDPC code.Accordingly,an algorithm for selecting the information bits of the short code is proposed,and a specific two-stage decoding algorithm is presented.Simulation results demonstrate that the proposed doped LDPC code achieves up to 2.0 dB gain compared with the original LDPC code at a frame error rate of 10^(-6)Furthermore,the proposed design can lower the error floor of original LDPC Codes.展开更多
In response to the situation of the African healthcare system,the African Medicines Agency(AMA)was established by the African Union(AU)to regulate access to medicines and support the local manufacture of medications.T...In response to the situation of the African healthcare system,the African Medicines Agency(AMA)was established by the African Union(AU)to regulate access to medicines and support the local manufacture of medications.This study aimed to describe the factors that enabled the establishment of the African Medicines Agency and its successes,challenges,and perceived benefits.We reviewed data sources that explored the progress and challenges of the African Medicines Agency and Medicines Regulation in Africa.The SPIDER framework was used to organise the research focus and to extract the keywords for the literature search.The study data were obtained from PubMed Central,ScienceDirect,and Google Scholar.Out of 249 studies screened,19 were selected for this narrative review.Critical successes observed in the agency's establishment include the appointment of a Special Envoy,the selection of its headquarters,and the signing of its treaty by 37 member states.However,it is hindered by poor political commitment,differences in riskbenefits interpretation and organizational structure,weak legal and regulatory frameworks,inadequate financial mechanisms,and inadequate political and policy leadership in some member states.The value of AMA in achieving optimal health outcomes and its other benefits must be considered despite the challenges being encountered.Therefore,all member states should adopt the best procedures in signing and ratifying the treaty and implementing associated commitments to improve efficiency and accountability in African medicine regulation.展开更多
1.Objective The Altay Orogenic Belt in Xinjiang,China is located in the west of the Central Asian Orogenic Belt and in the transition zone between the Siberian Plate and the Kazakhstan-Junggar Plate,extending approxim...1.Objective The Altay Orogenic Belt in Xinjiang,China is located in the west of the Central Asian Orogenic Belt and in the transition zone between the Siberian Plate and the Kazakhstan-Junggar Plate,extending approximately 500 km in northern Xinjiang,China(Fig.1a).The Altay Orogenic Belt has undergone two-way accretion of the Paleozoic crust and the Meso-Cenozoic intracontinental orogeny,leading to the formation of large numbers of intermediate-acid intrusions.More than 100000 pegmatite veins have been discovered in the intermediate-acid intrusions,and they constitute an important rare metal metallogenic belt of China(Fig.1b).展开更多
Context: Antiretroviral therapies improve the prognosis of NeuroAIDS contrasting with a high frequency of Minor Neurocognitive Disorders (MND) even in aviremic subjects. Objective: The objective of this study is to pr...Context: Antiretroviral therapies improve the prognosis of NeuroAIDS contrasting with a high frequency of Minor Neurocognitive Disorders (MND) even in aviremic subjects. Objective: The objective of this study is to present the neurological and cognitive profile of People Living with HIV (PLHIV) initiating antiretroviral treatment in Kinshasa in the era of Dolutegravir (DTG). Methods: This is a multicenter, cross-sectional study with a descriptive aim carried out in 16 HIV Outpatient Treatment Centers (OTC) in Kinshasa from October 4, 2021 to February 15, 2022. The International HIV Dementia Scale (IHDS) correlated with the Activities of Daily Living (IADL) scale facilitated the categorization of NeuroCognitive Disorders (NCD) of PLHIV evaluated after carrying out a summary neurological examination. Results: Of the 96 patients recruited, 56.3% were women with a sex ratio of 0.68. The average age was 40.1 ± 12.1 years. The secondary education level was the majority at 64.6%. Malaria (44.8%) and tuberculosis (32.3%) were more common as opportunistic infections. They were alcoholics in (30.2%). Their history was heart disease (15.6%), high blood pressure (18.8%);drug abuse (10.4%). The IHDS score was light in 55.2% of cases. The correlation between IHDS/IADL watches asymptomatic neurocognitive impairments (ANI) in 77.1%, almost all of subjects are found with normal overall functioning (94.8%) and a disturbed neurological examination in 53.1% of cases with a predominance of motor impairments in 79.1%. Conclusion: In view of these results, early and systematic screening of NCD and associated factors remains necessary in our context. .展开更多
Dairy products have become one of the most prevalent daily foods worldwide,but safety concerns are rising.In dairy farming,unscrupulous traders misuse antibiotics to treat some diseases such as mastitis in cows,leadin...Dairy products have become one of the most prevalent daily foods worldwide,but safety concerns are rising.In dairy farming,unscrupulous traders misuse antibiotics to treat some diseases such as mastitis in cows,leading to antibiotic residues in dairy products.Rapid,sensitive,and simple detection methods for antibiotic residues are particularly important for food safety in dairy products.Traditional detection technology can effectively detect antibiotics,but there are defects such as complicated pre-treatment and high cost.Biosensors are widely used in food safety due to fast detection speed,low detection cost,strong anti-interference ability,and suitability for the field application.Nevertheless,these sensors often fail to trigger the signal conversion output due to low target concentration.To cope with this issue,some high-efficiency signal amplification systems can be introduced to improve the detection sensitivity and linear range of biosensors.In this review,we focused on:(i)Sources and toxicity of major antibiotics in animal-derived foods.(ii)Nanomaterial-mediated biosensors for real-time detection of target antibiotics in animal-derived foods.(iii)Signal amplification techniques to increase the sensitivity of biosensors.Finally,future prospects and challenges in this research field are discussed.展开更多
利用大体积进样技术(large vo lum e in jec tion,LVI),结合气相色谱-质谱方法对二英的测定效果进行了研究。同时与传统分流/不分流进样技术进行了对比。对进样体积为1,5,10,25,50和100μL的色谱图进行了分析。研究表明使用大体积进样方...利用大体积进样技术(large vo lum e in jec tion,LVI),结合气相色谱-质谱方法对二英的测定效果进行了研究。同时与传统分流/不分流进样技术进行了对比。对进样体积为1,5,10,25,50和100μL的色谱图进行了分析。研究表明使用大体积进样方式,在不影响色谱分离度的同时,大幅度提高了分析灵敏度。通过对土壤样品的检测,证明该方法可以用于环境样品的实际测定。展开更多
Objective Mafic magmas can form in different tectonic settings with various geochemical characteristics depending on their mantle sources. Basalts generated in back-arc basins provide valuable perspectives on mantle s...Objective Mafic magmas can form in different tectonic settings with various geochemical characteristics depending on their mantle sources. Basalts generated in back-arc basins provide valuable perspectives on mantle structure and composition, on controls for melt generation, and on the sources responsible for arc magma genesis.展开更多
Objective Eclogites are important indicators of ancient plate boundaries or paleosuture zones. Despite their great geological significance, very few investigations have been carried out in the Kunlun region. The Centr...Objective Eclogites are important indicators of ancient plate boundaries or paleosuture zones. Despite their great geological significance, very few investigations have been carried out in the Kunlun region. The Central East Kunlun fault zone was believed to be an Early Paleozoic suture zone, but there has been no reliable evidence for this, though studies on ophiolite, granite, and basic granulite indicate that the Early Paleozoic orogeny occurred in the East Kunlun. This work focused on the Dagele eclogites in Central East Kunlun to provide new constraints for the Central East Kunlun suture zone.展开更多
Climate change,urbanization,and population increase limit food availability.To sustain human existence,there is the need to increase food and agricultural production to mitigate the impact of these factors.Scientists ...Climate change,urbanization,and population increase limit food availability.To sustain human existence,there is the need to increase food and agricultural production to mitigate the impact of these factors.Scientists have been working for years on ways to increase food production.From plant breeding techniques to soil science,scientists have made tremendous progress.The rhizobiome has been proven to be important to crop production,and the impact of the rhizobiome on plant health cannot be overemphasized.Being rich in diverse complex microbial interactions,the rhizosphere has become a major force in recent plant growth promotion studies.The upsurge in next-generation sequencing applications with the various“omics”technologies is helping to unearth information relating to rhizosphere impact on plant growth.Explaining the complex interactions between and across microbial species present in the rhizosphere is important to further enhance our understanding of their mechanistic and mutualistic functions.Knowledge from this can be used in rhizosphere biome engineering for improved plant growth and yield in the face of the various biotic and abiotic challenges.展开更多
The Mayuan stratabound Pb-Zn deposit in Nanzheng,Shaanxi Province,is located in the northern margin of the Yangtze Plate,in the southern margin of the Beiba Arch.The orebodies are stratiform and hosted in breciated do...The Mayuan stratabound Pb-Zn deposit in Nanzheng,Shaanxi Province,is located in the northern margin of the Yangtze Plate,in the southern margin of the Beiba Arch.The orebodies are stratiform and hosted in breciated dolostone of the Sinian Dengying Formation.The ore minerals are primarily sphalerite and galena,and the gangue minerals comprise of dolomite,quartz,barite,calcite and solid bitumen.Fluid inclusions from ore-stage quartz and calcite have homogenization tempreatures from 98 to 337℃ and salinities from 7.7 wt%to 22.2 wt%（NaCl equiv.）.The vapor phase of the inclusions is mainly composed of CH_4 with minor CO_2 and H_2S.The δD_（fluid） values of fluid inclusions in quartz and calcite display a range from-68‰ to-113‰（SMOW）,and the δ^（18）O_（fluid）values calculated from δ^（18）O_（quartz） and δ^（18）O_（calcite） values range from 4.5‰ to 16.7‰（SMOW）.These data suggest that the ore-forming fluids may have been derived from evaporitic sea water that had reacted with organic matter.The δ^（13）C_（CH4） values of CH_4 in fluid inclusions range from-37.2‰ to-21.0‰（PDB）,suggesting that the CH_4 in the ore-forming fluids was mainly derived from organic matter.This,together with the abundance of solid bitumen in the ores,suggest that organic matter played an important role in mineralization,and that the thermochemical sulfate reduction（TSR） was the main mechanism of sulfide precipitation.The Mayuan Pb-Zn deposit is a carbonate-hosted epigenetic deposit that may be classified as a Mississippi Valley type（MVT） deposit.展开更多
Field investigation combined with detailed petrographic observation indicate that abundant oil,gas,and solid bitumen inclusions were entrapped in veins and cements of sedimentary rocks in the Dabashan foreland,which w...Field investigation combined with detailed petrographic observation indicate that abundant oil,gas,and solid bitumen inclusions were entrapped in veins and cements of sedimentary rocks in the Dabashan foreland,which were used to reconstruct the oil and gas migration history in the context of tectonic evolution.Three stages of veins were recognized and related to the collision between the North China block and the Yangtze block during the Indosinian orogeny from Late Triassic to Early Jurassic（Dl）,the southwest thrusting of the Qinling orogenic belt towards the Sichuan basin during the Yanshanian orogeny from Late Jurassic to Early Cretaceous（D2）,and extensional tectonics during Late Cretaceous to Paleogene（D3）,respectively.The occurrences of hydrocarbon inclusions in these veins and their homogenization temperatures suggest that oil was generated in the early stage of tectonic evolution,and gas was generated later,whereas solid bitumen was the result of pyrolysis of previously accumulated hydrocarbons.Three stages of hydrocarbon fluid inclusions were also identified in cements of carbonates and sandstones of gas beds in the Dabashan foreland belt and the Dabashan foreland depression（northeastern Sichuan basin）,which recorded oil/gas formation,migration,accumulation and destruction of paleo-reservoirs during the D2.Isotopic analysis of hydrocarbon fluid inclusions contained in vein minerals shows that δ^（13）C_1 of gas in fluid inclusions ranges from-17.0‰ to-30.4‰（PDB） and δD from-107.7‰ to-156.7‰（SMOW）,which indicates that the gas captured in the veins was migrated natural gas which may be correlated with gas from the gas-fields in northern Sichuan basin.Organic geochemical comparison between bitumen and potential source rocks indicates that the Lower Cambrian black shale and the Lower Permian black limestone were the most possible source rocks of the bitumen.Combined with tectonic evolution history of the Dabashan foreland,the results of this study suggest that oil was generated from the Paleozoic source rocks in the Dabashan area under normal burial thermal conditions before Indosinian tectonics and accumulated to form paleo-reservoirs during Indosinian collision between the North China block and the Yangtz block.The paleo-reservoirs were destroyed during the Yanshanian tectonic movement when the Dabashan foreland was formed.At the same time,oil in the paleo-reservoirs in the Dabashan foreland depression was pyrolyzed to transform to dry gas and the residues became solid bitumen.展开更多
基金supported by the National Key R&D Program of China(No.2021YFC2901802)project of the China Geological Survey(No.DD20240073)Key R&D Program of Shaanxi Province(No.2024GH-ZDXM-26).
文摘1.Objective The Eastern Junggar Kalamaili region in Xinjiang constitutes a significant tin metallogenic belt in northwest China(Fig.1a).It hosts four independent tin deposits-Kamusite,Ganliangzi,Beilekuduke,and Sareshenke-from west to east,supplemented by two tin mineralized points,namely Hongtujingzi and Sujiquan(Figs.1b).according to the ore type and the composition of gangue minerals,the tin deposits in the region are classified into two groups:Quartz vein type and greisen type,with the Sareshenke deposit ascribed to the former and the remainder to the latter.
基金Project(52276068)supported by the National Natural Science Foundation of China。
文摘This study examines the intricate occurrences of thermal and solutal Marangoni convection in three-layered flows of viscous fluids,with a particular emphasis on their relevance to renewable energy systems.This research examines the flow of a three-layered viscous fluid,considering the combined influence of heat and solutal buoyancy driven Rayleigh-Bénard convection,as well as thermal and solutal Marangoni convection.The homotopy perturbation method is used to examine and simulate complex fluid flow and transport phenomena,providing important understanding of the fundamental physics and assisting in the optimization of various battery configurations.The inquiry examines the primary elements that influence Marangoni convection and its impact on battery performance,providing insights on possible enhancements in energy storage devices.The findings indicate that the velocity profiles shown graphically exhibit a prominent core zone characterized by the maximum speed,which progressively decreases as it approaches the walls of the channel.This study enhances our comprehension of fluid dynamics and the transmission of heat and mass in intricate systems,which has substantial ramifications for the advancement of sustainable energy solutions.
文摘Existing conventional megajoule plasma focus machines with 2–3 MA are producing fusion neutron yields of several times 10^(11) in deuterium operation,the fusion yields predominantly being the beam-gas target.Increasing the current to 10 MA and using 50%–50%D-T mixture will scale the neutron yield towards 10^(16) D-T fusion neutrons.In this work,we derive the Lawson criterion for plasma focus devices with a beam-target fusion neutron mechanism,so that we may glimpse what future technological advancements are needed for a break-even Q=1 plasma focus.We perform numerical experiments with a present-day feasible 0.9 MV,8.1 MJ,11 MA machine operating in 100 Torr in 50%–50%D-T mixture.The Lee Code simulation gives a detailed description of the plasma focus dynamics through each phase,and provides plasma and yield parameters which show that out of 1.1×10^(19) fast beam ions produced in the plasma focus pinch,only 1.24×10^(14) ions take part in beam-target fusion reactions within the pinch,producing the same number of D-T neutrons.The remnant beam ions,numbering at least 10^(19),exit the focus pinch at 1.9 MeV,which is far above the 115 keV ion energy necessary for an optimum beam-target cross-section.We propose to regain the lost fusion rates by using a high-pressure D-T-filled drift-tube to attenuate the energy of the remnant beam ions until they reach the energy for the optimum fusion cross-section.Such a fusion enhancement tube would further harvest beam-target fusion reactions by increasing the interaction path length(1 m)at increased interaction density(6 atm).A gain factor of 300 is conservatively estimated,with a final yield of 3.7×10^(16) D-T neutrons carrying kinetic energy of 83.6 kJ,demonstrating Q=0.01.
基金funded by the National Nature Science Foundation of China(81,825,019 and 82,330,103)performed with approval from the Ethical Committee of Beijing Institute of Microbiology and Epidemiology(AF/SC-08/02.128).
文摘Dear Editor,Severe fever with thrombocytopenia syndrome(SFTS)is an emerging tick-borne infectious disease caused by a novel bunyavirus called SFTS virus(SFTSV).It was initially identified in China in 2009(Yu et al.,2011).Since then,the number of reported SFTS cases has rapidly increased in China,South Korea,and Japan(Li,et al.,2018;Takahashi et al.,2014;Kim et al.,2018).Sporadic SFTS cases have also been identified in several other Asian countries,such as Vietnam,Pakistan,Myanmar,and Thailand(Takahashi et al.,2014;Tran et al.,2019;Li et al.,2021).This disease is recognized as a highly lethal viral hemorrhagic fever with a mortality rate ranging from 12%to 50%(Yu et al.,2011;Li et al.,2018;Takahashi et al.,2014;Kim et al.,2013).SFTS primarily spreads to humans through bites from ticks infected with SFTSV,with the Haemaphysalis longicornis tick acting as the predominant vector for SFTSV(Zhuang et al.,2018).
基金supported by the National Natural Science Foundation of China(Nos.42372115,92155305,92055314)the Innovation Capability Support Program of Shaanxi Province(No.2022KJXX-91)+2 种基金the Basic Research Program of Natural Science in Shaanxi Province(No.2023-JC-QN-0281)the International Geoscience Program(NoIGCP-741)China Geological Survey(No.DD20201159).
文摘0 INTRODUCTION Sedimentary exhalative(SEDEX)lead-zinc deposit was traditionally considered as a result of submarine hydrothermal exhalation,including exhalative plume and brine pool models(Izanloo et al.,2022;Spinks et al.,2021;Maghfouri et al.,2020;Sangster,2020,2018;Huang et al.,2019;Rajabi et al.,2015;Goodfellow and Lydon,2007;Large et al.,2005,2001;Peng et al.,2000;Goodfellow et al.,1993;Figures 1a,1b).However,recognition of mineralization as subseafloor hydrothermal replacement in a few SEDEX deposits has challenged the traditional consideration(Magnall et al.,2023,2021,2020a,b;Hayward et al.,2021;Figure 1c).Researchers come to believe that subseafloor replacement rather than submarine exhalation is a dominant process for SEDEX mineralization,but this needs to be examined through more case studies.
基金the South African National Space Agency (SANSA) for funding this work
文摘This paper is devoted to the investigation of the Landau–Ginzburg–Higgs equation(LGHe),which serves as a mathematical model to understand phenomena such as superconductivity and cyclotron waves.The LGHe finds applications in various scientific fields,including fluid dynamics,plasma physics,biological systems,and electricity-electronics.The study adopts Lie symmetry analysis as the primary framework for exploration.This analysis involves the identification of Lie point symmetries that are admitted by the differential equation.By leveraging these Lie point symmetries,symmetry reductions are performed,leading to the discovery of group invariant solutions.To obtain explicit solutions,several mathematical methods are applied,including Kudryashov's method,the extended Jacobi elliptic function expansion method,the power series method,and the simplest equation method.These methods yield solutions characterized by exponential,hyperbolic,and elliptic functions.The obtained solutions are visually represented through 3D,2D,and density plots,which effectively illustrate the nature of the solutions.These plots depict various patterns,such as kink-shaped,singular kink-shaped,bell-shaped,and periodic solutions.Finally,the paper employs the multiplier method and the conservation theorem introduced by Ibragimov to derive conserved vectors.These conserved vectors play a crucial role in the study of physical quantities,such as the conservation of energy and momentum,and contribute to the understanding of the underlying physics of the system.
基金supported by the Czech Ministry of Education,Youth and Sports(Project No.CZ.02.2.69/0.0/0.0/18_053/0016980)the Grant Agency of the Czech Republic(Grant No.GM23-05027M).
文摘Directed x-rays produced in the interaction of sub-picosecond laser pulses of moderate relativistic intensity with plasma of near-critical density are investigated. Synchrotron-like (betatron) radiation occurs in the process of direct laser acceleration (DLA) of electrons in a relativisticlaser channel when the electrons undergo transverse betatron oscillations in self-generated quasi-static electric and magnetic fields. In anexperiment at the PHELIX laser system, high-current directed beams of DLA electrons with a mean energy ten times higher than the ponderomotive potential and maximum energy up to 100 MeV were measured at 10^(19) W/cm^(2)laser intensity. The spectrum of directed x-raysin the range of 5–60 keV was evaluated using two sets of Ross filters placed at 0°and 10°to the laser pulse propagation axis. The differential x-ray absorption method allowed for absolute measurements of the angular-dependent photon fluence. We report 10^(13) photons/sr withenergies >5 keV measured at 0°to the laser axis and a brilliance of 10^(21) photons s^(−1) mm^(−2) mrad−2(0.1%BW)−1. The angular distributionof the emission has an FWHM of 14°–16°. Thanks to the ultra-high photon fluence, point-like radiation source, and ultra-short emissiontime, DLA-based keV backlighters are promising for various applications in high-energy-density research with kilojoule petawatt-class laserfacilities.
文摘Introduction:Parkinson’s disease(PD)is the most common neurodegenerative movement disorder.The pathological hallmark is the progressive loss of dopaminergic neurons of the substantia nigra pars compacta,which is accompanied by widespread alterations in the structu re and function of distributed brain networks.Togethe r,these processes cause a variety of motor symptoms such as bradykinesia,rigidity,tremor,gait disorders,or difficulties in fine motor control(Bange et al.,2022).
基金supported in part by China NSF under Grants No.61771081 and 62072064the Fundamental Research Funds for the Central Universities(China)under Grant cstc2019jcyjmsxmX0110+2 种基金the Project of Chongqing Natural Science Foundation under Grant CSTB2022NSCQ-MSX0990Science and Technology Research Project of Chongqing Education Commission under Grant KJQN202000612the Venture and Innovation Support Program for Chongqing Overseas Returnees under Grant cx2020070.
文摘In this paper,we propose a doping approach to lower the error floor of Low-Density Parity-Check(LDPC)codes.The doping component is a short block code in which the information bits are selected from the coded bits of the dominant trapping sets of the LDPC code.Accordingly,an algorithm for selecting the information bits of the short code is proposed,and a specific two-stage decoding algorithm is presented.Simulation results demonstrate that the proposed doped LDPC code achieves up to 2.0 dB gain compared with the original LDPC code at a frame error rate of 10^(-6)Furthermore,the proposed design can lower the error floor of original LDPC Codes.
文摘In response to the situation of the African healthcare system,the African Medicines Agency(AMA)was established by the African Union(AU)to regulate access to medicines and support the local manufacture of medications.This study aimed to describe the factors that enabled the establishment of the African Medicines Agency and its successes,challenges,and perceived benefits.We reviewed data sources that explored the progress and challenges of the African Medicines Agency and Medicines Regulation in Africa.The SPIDER framework was used to organise the research focus and to extract the keywords for the literature search.The study data were obtained from PubMed Central,ScienceDirect,and Google Scholar.Out of 249 studies screened,19 were selected for this narrative review.Critical successes observed in the agency's establishment include the appointment of a Special Envoy,the selection of its headquarters,and the signing of its treaty by 37 member states.However,it is hindered by poor political commitment,differences in riskbenefits interpretation and organizational structure,weak legal and regulatory frameworks,inadequate financial mechanisms,and inadequate political and policy leadership in some member states.The value of AMA in achieving optimal health outcomes and its other benefits must be considered despite the challenges being encountered.Therefore,all member states should adopt the best procedures in signing and ratifying the treaty and implementing associated commitments to improve efficiency and accountability in African medicine regulation.
基金Supported by the Natural Science Foundation of Shaanxi Province(2024JC-ZDXM-22,2020JM-311)the Project of China Geological Survey(DD20240128,DD20230284,DD20221636)。
文摘1.Objective The Altay Orogenic Belt in Xinjiang,China is located in the west of the Central Asian Orogenic Belt and in the transition zone between the Siberian Plate and the Kazakhstan-Junggar Plate,extending approximately 500 km in northern Xinjiang,China(Fig.1a).The Altay Orogenic Belt has undergone two-way accretion of the Paleozoic crust and the Meso-Cenozoic intracontinental orogeny,leading to the formation of large numbers of intermediate-acid intrusions.More than 100000 pegmatite veins have been discovered in the intermediate-acid intrusions,and they constitute an important rare metal metallogenic belt of China(Fig.1b).
文摘Context: Antiretroviral therapies improve the prognosis of NeuroAIDS contrasting with a high frequency of Minor Neurocognitive Disorders (MND) even in aviremic subjects. Objective: The objective of this study is to present the neurological and cognitive profile of People Living with HIV (PLHIV) initiating antiretroviral treatment in Kinshasa in the era of Dolutegravir (DTG). Methods: This is a multicenter, cross-sectional study with a descriptive aim carried out in 16 HIV Outpatient Treatment Centers (OTC) in Kinshasa from October 4, 2021 to February 15, 2022. The International HIV Dementia Scale (IHDS) correlated with the Activities of Daily Living (IADL) scale facilitated the categorization of NeuroCognitive Disorders (NCD) of PLHIV evaluated after carrying out a summary neurological examination. Results: Of the 96 patients recruited, 56.3% were women with a sex ratio of 0.68. The average age was 40.1 ± 12.1 years. The secondary education level was the majority at 64.6%. Malaria (44.8%) and tuberculosis (32.3%) were more common as opportunistic infections. They were alcoholics in (30.2%). Their history was heart disease (15.6%), high blood pressure (18.8%);drug abuse (10.4%). The IHDS score was light in 55.2% of cases. The correlation between IHDS/IADL watches asymptomatic neurocognitive impairments (ANI) in 77.1%, almost all of subjects are found with normal overall functioning (94.8%) and a disturbed neurological examination in 53.1% of cases with a predominance of motor impairments in 79.1%. Conclusion: In view of these results, early and systematic screening of NCD and associated factors remains necessary in our context. .
基金We thank the Natural Science Foundation of Hubei Province of China(2023AFB330)the China Postdoctoral Science Foundation(2022M721275)the Hubei Provincial Market Supervision Administration Science and Technology Program Project(Hbscjg-KJ2021002)for financial support.
文摘Dairy products have become one of the most prevalent daily foods worldwide,but safety concerns are rising.In dairy farming,unscrupulous traders misuse antibiotics to treat some diseases such as mastitis in cows,leading to antibiotic residues in dairy products.Rapid,sensitive,and simple detection methods for antibiotic residues are particularly important for food safety in dairy products.Traditional detection technology can effectively detect antibiotics,but there are defects such as complicated pre-treatment and high cost.Biosensors are widely used in food safety due to fast detection speed,low detection cost,strong anti-interference ability,and suitability for the field application.Nevertheless,these sensors often fail to trigger the signal conversion output due to low target concentration.To cope with this issue,some high-efficiency signal amplification systems can be introduced to improve the detection sensitivity and linear range of biosensors.In this review,we focused on:(i)Sources and toxicity of major antibiotics in animal-derived foods.(ii)Nanomaterial-mediated biosensors for real-time detection of target antibiotics in animal-derived foods.(iii)Signal amplification techniques to increase the sensitivity of biosensors.Finally,future prospects and challenges in this research field are discussed.
文摘利用大体积进样技术(large vo lum e in jec tion,LVI),结合气相色谱-质谱方法对二英的测定效果进行了研究。同时与传统分流/不分流进样技术进行了对比。对进样体积为1,5,10,25,50和100μL的色谱图进行了分析。研究表明使用大体积进样方式,在不影响色谱分离度的同时,大幅度提高了分析灵敏度。通过对土壤样品的检测,证明该方法可以用于环境样品的实际测定。
基金supported by the Sub Project of "National Key Research and Development Plan of China"-"Study on the Distribution Rule of Tianshan-Altai Bulk Minerals and Evaluation of Deep Resource Potential" (grant No. 2018YFC0604001)the Xinjiang Geological Exploration Fund (grant No. A16-1-LQ14)the National Natural Science Foundation of China (grants No. 41273033 and 41303027)
文摘Objective Mafic magmas can form in different tectonic settings with various geochemical characteristics depending on their mantle sources. Basalts generated in back-arc basins provide valuable perspectives on mantle structure and composition, on controls for melt generation, and on the sources responsible for arc magma genesis.
基金co-supported by the National Natural Science Foundation of China(grant No.41302070)the Fundamental Research Funds for the Central Universities (grants No.310827172004 and 310827173401)Geological Exploration Fund Project of Qinghai Province (grant No.2012209)
文摘Objective Eclogites are important indicators of ancient plate boundaries or paleosuture zones. Despite their great geological significance, very few investigations have been carried out in the Kunlun region. The Central East Kunlun fault zone was believed to be an Early Paleozoic suture zone, but there has been no reliable evidence for this, though studies on ophiolite, granite, and basic granulite indicate that the Early Paleozoic orogeny occurred in the East Kunlun. This work focused on the Dagele eclogites in Central East Kunlun to provide new constraints for the Central East Kunlun suture zone.
基金funded by the National Research Foundation(NRF)of South Africa(UID123634 and UID132595)which was granted to Olubukola O.Babalola。
文摘Climate change,urbanization,and population increase limit food availability.To sustain human existence,there is the need to increase food and agricultural production to mitigate the impact of these factors.Scientists have been working for years on ways to increase food production.From plant breeding techniques to soil science,scientists have made tremendous progress.The rhizobiome has been proven to be important to crop production,and the impact of the rhizobiome on plant health cannot be overemphasized.Being rich in diverse complex microbial interactions,the rhizosphere has become a major force in recent plant growth promotion studies.The upsurge in next-generation sequencing applications with the various“omics”technologies is helping to unearth information relating to rhizosphere impact on plant growth.Explaining the complex interactions between and across microbial species present in the rhizosphere is important to further enhance our understanding of their mechanistic and mutualistic functions.Knowledge from this can be used in rhizosphere biome engineering for improved plant growth and yield in the face of the various biotic and abiotic challenges.
基金granted by the China State Mineral Resources Investigation Program(Grant No. 1212011121117)the National Natural Science Foudation of China(Grant No.41102050)the Central University Fund(310827153407)
文摘The Mayuan stratabound Pb-Zn deposit in Nanzheng,Shaanxi Province,is located in the northern margin of the Yangtze Plate,in the southern margin of the Beiba Arch.The orebodies are stratiform and hosted in breciated dolostone of the Sinian Dengying Formation.The ore minerals are primarily sphalerite and galena,and the gangue minerals comprise of dolomite,quartz,barite,calcite and solid bitumen.Fluid inclusions from ore-stage quartz and calcite have homogenization tempreatures from 98 to 337℃ and salinities from 7.7 wt%to 22.2 wt%（NaCl equiv.）.The vapor phase of the inclusions is mainly composed of CH_4 with minor CO_2 and H_2S.The δD_（fluid） values of fluid inclusions in quartz and calcite display a range from-68‰ to-113‰（SMOW）,and the δ^（18）O_（fluid）values calculated from δ^（18）O_（quartz） and δ^（18）O_（calcite） values range from 4.5‰ to 16.7‰（SMOW）.These data suggest that the ore-forming fluids may have been derived from evaporitic sea water that had reacted with organic matter.The δ^（13）C_（CH4） values of CH_4 in fluid inclusions range from-37.2‰ to-21.0‰（PDB）,suggesting that the CH_4 in the ore-forming fluids was mainly derived from organic matter.This,together with the abundance of solid bitumen in the ores,suggest that organic matter played an important role in mineralization,and that the thermochemical sulfate reduction（TSR） was the main mechanism of sulfide precipitation.The Mayuan Pb-Zn deposit is a carbonate-hosted epigenetic deposit that may be classified as a Mississippi Valley type（MVT） deposit.
基金funded by CNSF(No.41173055)the Research Program of China Geological Survey(No. 1212011121117)
文摘Field investigation combined with detailed petrographic observation indicate that abundant oil,gas,and solid bitumen inclusions were entrapped in veins and cements of sedimentary rocks in the Dabashan foreland,which were used to reconstruct the oil and gas migration history in the context of tectonic evolution.Three stages of veins were recognized and related to the collision between the North China block and the Yangtze block during the Indosinian orogeny from Late Triassic to Early Jurassic（Dl）,the southwest thrusting of the Qinling orogenic belt towards the Sichuan basin during the Yanshanian orogeny from Late Jurassic to Early Cretaceous（D2）,and extensional tectonics during Late Cretaceous to Paleogene（D3）,respectively.The occurrences of hydrocarbon inclusions in these veins and their homogenization temperatures suggest that oil was generated in the early stage of tectonic evolution,and gas was generated later,whereas solid bitumen was the result of pyrolysis of previously accumulated hydrocarbons.Three stages of hydrocarbon fluid inclusions were also identified in cements of carbonates and sandstones of gas beds in the Dabashan foreland belt and the Dabashan foreland depression（northeastern Sichuan basin）,which recorded oil/gas formation,migration,accumulation and destruction of paleo-reservoirs during the D2.Isotopic analysis of hydrocarbon fluid inclusions contained in vein minerals shows that δ^（13）C_1 of gas in fluid inclusions ranges from-17.0‰ to-30.4‰（PDB） and δD from-107.7‰ to-156.7‰（SMOW）,which indicates that the gas captured in the veins was migrated natural gas which may be correlated with gas from the gas-fields in northern Sichuan basin.Organic geochemical comparison between bitumen and potential source rocks indicates that the Lower Cambrian black shale and the Lower Permian black limestone were the most possible source rocks of the bitumen.Combined with tectonic evolution history of the Dabashan foreland,the results of this study suggest that oil was generated from the Paleozoic source rocks in the Dabashan area under normal burial thermal conditions before Indosinian tectonics and accumulated to form paleo-reservoirs during Indosinian collision between the North China block and the Yangtz block.The paleo-reservoirs were destroyed during the Yanshanian tectonic movement when the Dabashan foreland was formed.At the same time,oil in the paleo-reservoirs in the Dabashan foreland depression was pyrolyzed to transform to dry gas and the residues became solid bitumen.
