AIM: To investigate the acupuncture-modulated gastric motility and its underlying neural mechanism.METHODS: Intragastric pressure and/or waves of gastric contraction in rats were recorded by intrapyloric balloon and c...AIM: To investigate the acupuncture-modulated gastric motility and its underlying neural mechanism.METHODS: Intragastric pressure and/or waves of gastric contraction in rats were recorded by intrapyloric balloon and changes of gastric motility induced by acupuncture stimulation were compared with the background activity before any stimulation. Gastro-vagal or splanchnic-sympathetic nerves were recorded or cut respectively for investigating the involvement of autonomic nerve pathways. Spinalization experiment was also performed.RESULTS: Acupuncture-stimulation by exciting Aδ and/or C afferent fibers, could only modulate gastric motility. Acupuncture-stimulation on fore- and hind-limbs evoked a moderate gastric motility followed by increased vagus discharges with unchanged sympathetic activity, while the same stimulus to the acupoints in abdomen resulted in reversed effects on gastric motility and autonomic nervous activities. The inhibitory gastric response was completely abolished by splanchnic denervation, but the facilitative gastric response to stimulation of acupoints in limbs was not influenced, which was opposite to the effect when vagotomy was performed. The similar depressive effects were produced by the stimulation at the acupoints homo-segmental to the gastric innervation in the animals with or without spinalization. However, the facilitation induced by the stimulation at the acupoints hetero-segmental to the gastric innervation was not observed in the spinalized animals.CONCLUSION: Facilitative effects of stimulating hetero-segmental acupoints are involved in the intact preparation of vagal nerves and spinal cord, while the inhibitory response induced by stimulating homo-segmental acupoints is involved in the intact preparation of sympathetic nerves. Only the acupuncture-stimulation with intensity over the threshold of Aδ and/or C afferent fibers can markedly modulate gastrointestinal motility.展开更多
Numbness is one of the chief symptoms ofcerebral arteriosclerosis.The author treated 60cases of the disease satisfactorily and reports theresults as follows.CLINICAL MATERALSOf the 60 patients,39 were males and 21fema...Numbness is one of the chief symptoms ofcerebral arteriosclerosis.The author treated 60cases of the disease satisfactorily and reports theresults as follows.CLINICAL MATERALSOf the 60 patients,39 were males and 21females.The age distribution was for 30展开更多
A set of scientific theories and an effective acupuncture therapy for insomnia about ＂the needling method for tranquillization and calming the mind＂ are gradually formed through many years＇theoretical and clinical ...A set of scientific theories and an effective acupuncture therapy for insomnia about ＂the needling method for tranquillization and calming the mind＂ are gradually formed through many years＇theoretical and clinical studies. In this paper, the theoretical intention about ＂the needling method for tranquillization and calming the mind＂ for treatment of insomnia are briefly introduced mainly from the cause of disease, pathogenesis, therapeutic method and characteristics of composition of a prescription, etc. in order to provide a new train of thoughts and a new method for working out scientific and standard prescriptions in the treatment of insomnia.展开更多
Dr.Shao Jingming has been engaged inclinical acupuncture teaching for more than60 years and accumulated rich experience.He has always put stresses on differentiationof diseases according to pathologicalchanges of the ...Dr.Shao Jingming has been engaged inclinical acupuncture teaching for more than60 years and accumulated rich experience.He has always put stresses on differentiationof diseases according to pathologicalchanges of the viscera and theirinterrelations,and proposed utilization ofthe Back—Shu points in treatment of dis-eases.He is good at treating diseases by se-lecting.few but highly effective acupoints. Inthis paper the authors summarize the expe-rience of Dr.Shao in the clinical applicationof Back—Shu points,and would like to展开更多
AIM： To investigate whether manual acupuncture at representative acupoints in different parts of the body can modulate responses of gastric motility in rats and regular effects in different acupoint stimulation. METH...AIM： To investigate whether manual acupuncture at representative acupoints in different parts of the body can modulate responses of gastric motility in rats and regular effects in different acupoint stimulation. METHODS： The gastric motor activity of rats was recorded by the intrapyloric balloon. The changes of gastric motility induced by the stimulation were compared with the background activity in intragastric pressure and/or waves of gastric contraction recorded before any stimulation. Morphological study was also conducted by observing the Evans dye extravasation in the skin after mustard oil injection into the intragastric mucous membrane to certify cutaneous innervations of blue dots related to gastric segmental innervations. RESULTS： In all six rats that received mustard oil injections into intragastric mucosa, small blue dots appeared in the skin over the whole abdomen, but mainly in peri-midline upper- and middle- abdomen and middle-back, a few in thigh and groin. It may speculate that cutaneous innervations of blue dots have the same distribution as gastric segmental innervations. Acustimulation in acupoints of head-neck, four limbs, upper chest-dorsum and Iower-dorsum induced markedly augmentation of gastric motility （acupoints on headneck such as St-2： n = 16, 105.19 ± 1.36 vs 112.25 ± 2.02 and St-3： n = 14, 101.5 ± 1.75 vs 109.36 ± 1.8; acupoints on limbs such as Sp-6： n = 19, 100.74 ± 1.54 vs 110.26 ± 3.88; St-32： n = 17, 103.59 ± 1.64 vs 108.24 ± 2.41; St-36： n = 16, 104.81 ± 1.72 vs 110.81 ± 2.74 and U-11： n = 17, 106.47 ± 2.61 vs 114.77 ± 3.77, P 〈 0.05-0.001）. Vigorous inhibitory regulations of gastric motility induced by acu-stimulation applied in acupoints on whole abdomen and middle-dorsum were significantly different as compared with the controls before acu-stimulation （abdomen acupoints such as Cv-12： n = 11, 109.36 ± 2.09 vs 101 ± 2.21; Cv-6： n = 18, 104.39 ± 1.42 vs 91.83 ± 3.22 and St-21： n = 12, 107 ± 2.97 vs 98.58 ± 2.81; acupoints on middledorsum such as BI-17： n = 19, 100.63 ± 1.4 vs 92.21 ± 2.07 and BI-21： n = 19, 103.84 ± 1.48 vs 97.58 ± 2.16, P 〈 0.05-0.001）. CONCLUSION： Regular regulatory effects of facilitation and inhibition on gastric motility appear to be somatotopically organized in the acupoints of whole body, and the effective regularity of site-special acupoints on gastric motility is involved in segmental innervations between stomach and acupoints.展开更多
Acupuncture has been used to treat ischemic stroke,and mounting evidence demonstrates the neuroprotective and autophagy‑mediated actions of electroacupuncture(EA).This review summarizes the evidence that EA affects di...Acupuncture has been used to treat ischemic stroke,and mounting evidence demonstrates the neuroprotective and autophagy‑mediated actions of electroacupuncture(EA).This review summarizes the evidence that EA affects different stages of autophagy,its neuroprotective action,and effects of different acupoints in treating ischemic stroke.Systematic searches were conducted on English and Chinese databases(MEDLINE,Elsevier,ScienceDirect,Cochrane Library,and China National Knowledge Infrastructure).Studies published up until February 2021 were considered for inclusion,and a final of fifty articles were included in this review.There is evidence that acupuncture promotes neuroprotection by modulating autophagy,and the treatment effectiveness is related to the acupoint selection and timing of treatment administration.展开更多
Purpose： In order to make a report on 90 cases of insomnia treated by the Wei-defensive qi-regulating and brain-strengthening needling technique, as a clinical subject of the multiple center, for assessing the prelim...Purpose： In order to make a report on 90 cases of insomnia treated by the Wei-defensive qi-regulating and brain-strengthening needling technique, as a clinical subject of the multiple center, for assessing the preliminary standardized indications and operating methods and making an initial summary for writing the draft of the technique operation. Methods： By ratio of 1：1, the patients in conformity with the criteria were randomly divided into the experimental group and control group. In the experimental group, 45 cases were treated with the Wei-defensive qi-regulating and brain-strengthening needling technique on Baihui （GV 20）, Dazhui （GV 14）, Shenmai （BL 62）, Zhaohai （KJ 6）, plus ear points. In the control group, 45 cases were treated with routine acupuncture on Sishencong （Ex-HN 1）, Shenmen （HT 7）, Sanyinjiao （SP 6）, etc. The therapeutic effects in the two groups were observed and assessed in comparison. Results： The results showed cure in 15 cases, remarkable effect in 27 cases, effect in 42 cases, failure in 6 cases, and the total effective rate in 94.4% in 90 cases of insomnia. In the three centers, the statistic management was performed based upon PSQI integral and showed significant difference （P〈0.01）, and no significant difference among various groups （P〉0.01）. Conclusion： The therapeutic effect in the treatment of insomnia by Wei-defensive qi-regulating and brain-strengthening needling technique is better than the control group and the therapeutic effect and methods in various centers are stable, without any deviation.展开更多
基金Supported by National Natural Science Foundation of China, No. C30100245 National Basic Research 973 Program, No. 2005CB523308
文摘AIM: To investigate the acupuncture-modulated gastric motility and its underlying neural mechanism.METHODS: Intragastric pressure and/or waves of gastric contraction in rats were recorded by intrapyloric balloon and changes of gastric motility induced by acupuncture stimulation were compared with the background activity before any stimulation. Gastro-vagal or splanchnic-sympathetic nerves were recorded or cut respectively for investigating the involvement of autonomic nerve pathways. Spinalization experiment was also performed.RESULTS: Acupuncture-stimulation by exciting Aδ and/or C afferent fibers, could only modulate gastric motility. Acupuncture-stimulation on fore- and hind-limbs evoked a moderate gastric motility followed by increased vagus discharges with unchanged sympathetic activity, while the same stimulus to the acupoints in abdomen resulted in reversed effects on gastric motility and autonomic nervous activities. The inhibitory gastric response was completely abolished by splanchnic denervation, but the facilitative gastric response to stimulation of acupoints in limbs was not influenced, which was opposite to the effect when vagotomy was performed. The similar depressive effects were produced by the stimulation at the acupoints homo-segmental to the gastric innervation in the animals with or without spinalization. However, the facilitation induced by the stimulation at the acupoints hetero-segmental to the gastric innervation was not observed in the spinalized animals.CONCLUSION: Facilitative effects of stimulating hetero-segmental acupoints are involved in the intact preparation of vagal nerves and spinal cord, while the inhibitory response induced by stimulating homo-segmental acupoints is involved in the intact preparation of sympathetic nerves. Only the acupuncture-stimulation with intensity over the threshold of Aδ and/or C afferent fibers can markedly modulate gastrointestinal motility.
文摘Numbness is one of the chief symptoms ofcerebral arteriosclerosis.The author treated 60cases of the disease satisfactorily and reports theresults as follows.CLINICAL MATERALSOf the 60 patients,39 were males and 21females.The age distribution was for 30
文摘A set of scientific theories and an effective acupuncture therapy for insomnia about ＂the needling method for tranquillization and calming the mind＂ are gradually formed through many years＇theoretical and clinical studies. In this paper, the theoretical intention about ＂the needling method for tranquillization and calming the mind＂ for treatment of insomnia are briefly introduced mainly from the cause of disease, pathogenesis, therapeutic method and characteristics of composition of a prescription, etc. in order to provide a new train of thoughts and a new method for working out scientific and standard prescriptions in the treatment of insomnia.
文摘Dr.Shao Jingming has been engaged inclinical acupuncture teaching for more than60 years and accumulated rich experience.He has always put stresses on differentiationof diseases according to pathologicalchanges of the viscera and theirinterrelations,and proposed utilization ofthe Back—Shu points in treatment of dis-eases.He is good at treating diseases by se-lecting.few but highly effective acupoints. Inthis paper the authors summarize the expe-rience of Dr.Shao in the clinical applicationof Back—Shu points,and would like to
基金Supported by the National Natural Science Foundation of China, No. C30100245 and National Basic Research 973 Program, No. 2005CB523308
文摘AIM： To investigate whether manual acupuncture at representative acupoints in different parts of the body can modulate responses of gastric motility in rats and regular effects in different acupoint stimulation. METHODS： The gastric motor activity of rats was recorded by the intrapyloric balloon. The changes of gastric motility induced by the stimulation were compared with the background activity in intragastric pressure and/or waves of gastric contraction recorded before any stimulation. Morphological study was also conducted by observing the Evans dye extravasation in the skin after mustard oil injection into the intragastric mucous membrane to certify cutaneous innervations of blue dots related to gastric segmental innervations. RESULTS： In all six rats that received mustard oil injections into intragastric mucosa, small blue dots appeared in the skin over the whole abdomen, but mainly in peri-midline upper- and middle- abdomen and middle-back, a few in thigh and groin. It may speculate that cutaneous innervations of blue dots have the same distribution as gastric segmental innervations. Acustimulation in acupoints of head-neck, four limbs, upper chest-dorsum and Iower-dorsum induced markedly augmentation of gastric motility （acupoints on headneck such as St-2： n = 16, 105.19 ± 1.36 vs 112.25 ± 2.02 and St-3： n = 14, 101.5 ± 1.75 vs 109.36 ± 1.8; acupoints on limbs such as Sp-6： n = 19, 100.74 ± 1.54 vs 110.26 ± 3.88; St-32： n = 17, 103.59 ± 1.64 vs 108.24 ± 2.41; St-36： n = 16, 104.81 ± 1.72 vs 110.81 ± 2.74 and U-11： n = 17, 106.47 ± 2.61 vs 114.77 ± 3.77, P 〈 0.05-0.001）. Vigorous inhibitory regulations of gastric motility induced by acu-stimulation applied in acupoints on whole abdomen and middle-dorsum were significantly different as compared with the controls before acu-stimulation （abdomen acupoints such as Cv-12： n = 11, 109.36 ± 2.09 vs 101 ± 2.21; Cv-6： n = 18, 104.39 ± 1.42 vs 91.83 ± 3.22 and St-21： n = 12, 107 ± 2.97 vs 98.58 ± 2.81; acupoints on middledorsum such as BI-17： n = 19, 100.63 ± 1.4 vs 92.21 ± 2.07 and BI-21： n = 19, 103.84 ± 1.48 vs 97.58 ± 2.16, P 〈 0.05-0.001）. CONCLUSION： Regular regulatory effects of facilitation and inhibition on gastric motility appear to be somatotopically organized in the acupoints of whole body, and the effective regularity of site-special acupoints on gastric motility is involved in segmental innervations between stomach and acupoints.
基金This article was supported by the Key Scientific Research Program of Shanghai Municipal Science and Technology Committee in China(18401970500,16401970300)the Financing Scheme of Arising Interdisciplinary Subjects of TCM in Shanghai(Shxxjcxk201709)the TCM Genre Program of Shanghai Health Bureau(ZY[2018–2020]‑CCCX‑1006).
文摘Acupuncture has been used to treat ischemic stroke,and mounting evidence demonstrates the neuroprotective and autophagy‑mediated actions of electroacupuncture(EA).This review summarizes the evidence that EA affects different stages of autophagy,its neuroprotective action,and effects of different acupoints in treating ischemic stroke.Systematic searches were conducted on English and Chinese databases(MEDLINE,Elsevier,ScienceDirect,Cochrane Library,and China National Knowledge Infrastructure).Studies published up until February 2021 were considered for inclusion,and a final of fifty articles were included in this review.There is evidence that acupuncture promotes neuroprotection by modulating autophagy,and the treatment effectiveness is related to the acupoint selection and timing of treatment administration.
文摘Purpose： In order to make a report on 90 cases of insomnia treated by the Wei-defensive qi-regulating and brain-strengthening needling technique, as a clinical subject of the multiple center, for assessing the preliminary standardized indications and operating methods and making an initial summary for writing the draft of the technique operation. Methods： By ratio of 1：1, the patients in conformity with the criteria were randomly divided into the experimental group and control group. In the experimental group, 45 cases were treated with the Wei-defensive qi-regulating and brain-strengthening needling technique on Baihui （GV 20）, Dazhui （GV 14）, Shenmai （BL 62）, Zhaohai （KJ 6）, plus ear points. In the control group, 45 cases were treated with routine acupuncture on Sishencong （Ex-HN 1）, Shenmen （HT 7）, Sanyinjiao （SP 6）, etc. The therapeutic effects in the two groups were observed and assessed in comparison. Results： The results showed cure in 15 cases, remarkable effect in 27 cases, effect in 42 cases, failure in 6 cases, and the total effective rate in 94.4% in 90 cases of insomnia. In the three centers, the statistic management was performed based upon PSQI integral and showed significant difference （P〈0.01）, and no significant difference among various groups （P〉0.01）. Conclusion： The therapeutic effect in the treatment of insomnia by Wei-defensive qi-regulating and brain-strengthening needling technique is better than the control group and the therapeutic effect and methods in various centers are stable, without any deviation.
