Conventional orthogonal polynomial approach can solve the multilayered plate only when the material properties of two adjacent layers do not change significantly. This paper de- veloped an improved orthogonal polynomi...Conventional orthogonal polynomial approach can solve the multilayered plate only when the material properties of two adjacent layers do not change significantly. This paper de- veloped an improved orthogonal polynomial approach to solve wave propagation in multilayered plates with very dissimilar material properties. Through numerical comparisons among the exact solution, the results from the conventional polynomial approach and from the improved poly- nomial approach, the validity of the improved polynomial approach is illustrated. Finally, it is shown that the conventional polynomial approach can not yield correct continuous normal stress profiles. The improved orthogonul polynomial approach has overcome this drawback.展开更多
Objective:To examine the potential risk of hepatitis B virus(HBV)spread in Indonesia by migrant workers,based on the molecular characteristics of HBV strains.Methods:Sera collected from migrant workers traveling to th...Objective:To examine the potential risk of hepatitis B virus(HBV)spread in Indonesia by migrant workers,based on the molecular characteristics of HBV strains.Methods:Sera collected from migrant workers traveling to their destination countries(pre-migrant workers)and those returning to Indonesia(post-migrant workers)were screened for HBsAg by ELISA,followed by HBV DNA detection by PCR and(sub)genotype/subtype determination according to surface region and whole genome sequencing.Results:Of 87 pre-migrant workers,15(17.24%)were HBsAgpositive,whereas 15(12.10%)of 124 post-migrant workers were HBs Ag seropositive.HBV genotype analysis based on the S region showed that HBV-B3/adw2 was predominant(96.15%,25/26)whereas 3.85%(1/26)of isolates were HBV-C3/adrq+.Whole genome sequencing of selected strains and phylogenetic tree analysis identified subgenotype B7 in three samples previously categorized as subgenotype B3 based on S region analysis,supporting a recent argument that subgenotypes B5/B7/B8/B9 could be considered as a quasi-subgenotype of B3.Conclusions:A high prevalence of HBsAg carriers was detected among migrant workers from Lombok Island,with no significant difference in prevalence between before and after returning to Indonesia.All strains were classified into genotypes common in Indonesia,and the results suggested that migrant workers are not a risk factor for HBV transmission into Indonesia.展开更多
基金supported by the National Natural Science Foundation of China(No.11272115)
文摘Conventional orthogonal polynomial approach can solve the multilayered plate only when the material properties of two adjacent layers do not change significantly. This paper de- veloped an improved orthogonal polynomial approach to solve wave propagation in multilayered plates with very dissimilar material properties. Through numerical comparisons among the exact solution, the results from the conventional polynomial approach and from the improved poly- nomial approach, the validity of the improved polynomial approach is illustrated. Finally, it is shown that the conventional polynomial approach can not yield correct continuous normal stress profiles. The improved orthogonul polynomial approach has overcome this drawback.
基金partly supported by the Grant-in-Aid from the Ministry of Education,Culture,Sports,Science and Technology,Japan(16H05826)a Grant-in-Aid from the Japan Initiative for Global Research Network on Infectious Disease(J-GRID)supported by the Ministry of Education,Culture,Sports,Science and Technology,Japansupported by Grantin-Aid from Professor Dato’Sri Tahir through Tahir professorship,Indonesia.
文摘Objective:To examine the potential risk of hepatitis B virus(HBV)spread in Indonesia by migrant workers,based on the molecular characteristics of HBV strains.Methods:Sera collected from migrant workers traveling to their destination countries(pre-migrant workers)and those returning to Indonesia(post-migrant workers)were screened for HBsAg by ELISA,followed by HBV DNA detection by PCR and(sub)genotype/subtype determination according to surface region and whole genome sequencing.Results:Of 87 pre-migrant workers,15(17.24%)were HBsAgpositive,whereas 15(12.10%)of 124 post-migrant workers were HBs Ag seropositive.HBV genotype analysis based on the S region showed that HBV-B3/adw2 was predominant(96.15%,25/26)whereas 3.85%(1/26)of isolates were HBV-C3/adrq+.Whole genome sequencing of selected strains and phylogenetic tree analysis identified subgenotype B7 in three samples previously categorized as subgenotype B3 based on S region analysis,supporting a recent argument that subgenotypes B5/B7/B8/B9 could be considered as a quasi-subgenotype of B3.Conclusions:A high prevalence of HBsAg carriers was detected among migrant workers from Lombok Island,with no significant difference in prevalence between before and after returning to Indonesia.All strains were classified into genotypes common in Indonesia,and the results suggested that migrant workers are not a risk factor for HBV transmission into Indonesia.