Perovskite-type structures with the composition La Ni x Co1–x O3（x=0.3, 0.5, 0.7） were synthesized by a modified sol-gel method. Using transitional metal elements on the lanthanum base perovskites, properties could...Perovskite-type structures with the composition La Ni x Co1–x O3（x=0.3, 0.5, 0.7） were synthesized by a modified sol-gel method. Using transitional metal elements on the lanthanum base perovskites, properties could be tuned by doping the structure. Thermogravimetric analysis（TGA） evidenced a temperature of 350 °C as the start point of the perovskite-phase formation. Scanning electron microscopy（SEM） images showed the microstructure changes（grain size） of the cobalt-doped perovskite due to composition. In addition, it was shown that magnetic properties of the samples were dependent of cobalt content; experimental results pointed to the existence of disordered spins interactions, which were more evident with the decrease of cobalt content and the existence of ferromagnetic coupling among spins of the samples. These results showed the feasibility of producing a family of compounds with the desired properties, manipulating composition and therefore the microstructure.展开更多
The possibility of delivering DNA effi ciently to cells represents a crucial issue for the treatment of both genetic and acquired diseases.However,even although the effi ciency of non-viral transfection systems has im...The possibility of delivering DNA effi ciently to cells represents a crucial issue for the treatment of both genetic and acquired diseases.However,even although the effi ciency of non-viral transfection systems has improved in the last decade,none have yet proven to be suffi ciently effective in vivo.We report herein our results on the functionalization of single-walled carbon nanotubes(SWNT)and multi-walled carbon nanotubes(MWNT)by two cationic amphiphiles(lipid RPR120535 and pyrenyl polyamine),their use for the complexation of plasmid DNA,and their efficiency in transfecting cells in vitro.The experiments have shown that the efficiency of transfection is higher when using SWNT instead of MWNT,and that transfection effi ciency is similar or slightly higher when using nanoplexes(SWNT/lipid RPR120535/DNA)instead of lipoplexes(lipid RPR120535/DNA)and several orders of magnitude higher than that of naked DNA.This study therefore shows both that the transfection is better when using SWNTs and that it is dependent on the nature of the amphiphilic molecules adsorbed on the nanotubes.展开更多
1 Results Over the past few years significant research has been directed toward the development of organic materials for potential application in molecular photonic devices[1] and the development of sensors[2].Interes...1 Results Over the past few years significant research has been directed toward the development of organic materials for potential application in molecular photonic devices[1] and the development of sensors[2].Interest in these materials is primarily due to the infinite numbers of possible molecular structures with the desired properties,by virtue of the tremendous capabilities of organic synthesis.For the development of a new fluorescent molecular sensor consisting of a recognition moiety linked to a f...展开更多
基金Project supported by PROMEP,PAICy T,CIIDIT,FIME-UANL and the Consejo Nacional de Ciencia y Tecnología(CONACyT)through the project 139278 and ECOS 229381
文摘Perovskite-type structures with the composition La Ni x Co1–x O3（x=0.3, 0.5, 0.7） were synthesized by a modified sol-gel method. Using transitional metal elements on the lanthanum base perovskites, properties could be tuned by doping the structure. Thermogravimetric analysis（TGA） evidenced a temperature of 350 °C as the start point of the perovskite-phase formation. Scanning electron microscopy（SEM） images showed the microstructure changes（grain size） of the cobalt-doped perovskite due to composition. In addition, it was shown that magnetic properties of the samples were dependent of cobalt content; experimental results pointed to the existence of disordered spins interactions, which were more evident with the decrease of cobalt content and the existence of ferromagnetic coupling among spins of the samples. These results showed the feasibility of producing a family of compounds with the desired properties, manipulating composition and therefore the microstructure.
文摘The possibility of delivering DNA effi ciently to cells represents a crucial issue for the treatment of both genetic and acquired diseases.However,even although the effi ciency of non-viral transfection systems has improved in the last decade,none have yet proven to be suffi ciently effective in vivo.We report herein our results on the functionalization of single-walled carbon nanotubes(SWNT)and multi-walled carbon nanotubes(MWNT)by two cationic amphiphiles(lipid RPR120535 and pyrenyl polyamine),their use for the complexation of plasmid DNA,and their efficiency in transfecting cells in vitro.The experiments have shown that the efficiency of transfection is higher when using SWNT instead of MWNT,and that transfection effi ciency is similar or slightly higher when using nanoplexes(SWNT/lipid RPR120535/DNA)instead of lipoplexes(lipid RPR120535/DNA)and several orders of magnitude higher than that of naked DNA.This study therefore shows both that the transfection is better when using SWNTs and that it is dependent on the nature of the amphiphilic molecules adsorbed on the nanotubes.
文摘1 Results Over the past few years significant research has been directed toward the development of organic materials for potential application in molecular photonic devices[1] and the development of sensors[2].Interest in these materials is primarily due to the infinite numbers of possible molecular structures with the desired properties,by virtue of the tremendous capabilities of organic synthesis.For the development of a new fluorescent molecular sensor consisting of a recognition moiety linked to a f...
