植物性系统多样性对森林群落构建和生态系统功能维持具有重要意义。本文以浙江百山祖亚热带森林25 ha动态监测样地中胸径(diameter at breast height,DBH)≥1 cm的木本植物为研究对象,描述了样地内木本植物性系统多样性的格局,并检验了...植物性系统多样性对森林群落构建和生态系统功能维持具有重要意义。本文以浙江百山祖亚热带森林25 ha动态监测样地中胸径(diameter at breast height,DBH)≥1 cm的木本植物为研究对象,描述了样地内木本植物性系统多样性的格局,并检验了地形、土壤理化性质和演替对群落性系统数量特征的影响。结果表明:(1)样地内163种木本种子植物中有两性花植物95种,雌雄异株植物43种,雌雄同株异花植物25种,两性花在科、属、种和个体水平上的数量都占据优势;雌雄同株异花植物的平均胸径显著大于两性花和雌雄异株植物。(2)在样方水平,两性花植物数量同样占据主要优势,其次为雌雄异株植物和雌雄同株异花植物;在样地内,较高海拔的北坡性系统多样性较低,而较低海拔的南坡性系统多样性较高。(3)地形对植物群落性系统数量特征的影响大于理化因子;演替阶段同样对性系统数量特征具有重要影响,在演替早期物种黄山松(Pinus taiwanensis)和杉木(Cunninghamialanceolata)比例较高的样方中雌雄异株植物出现的频率更高,并因此具有更高的性系统多样性。本研究结果表明:植物性系统在森林群落构建过程中发挥重要作用,且地形、演替和土壤理化性质会共同塑造森林群落性系统多样性格局。展开更多
Bromodomain and plant homeodomain(PHD)finger containing protein 1(Brpf1)is an activator and scaffold protein of a multiunit complex that includes other components involving lysine acetyltransferase(KAT)6A/6B/7.Brpf1,K...Bromodomain and plant homeodomain(PHD)finger containing protein 1(Brpf1)is an activator and scaffold protein of a multiunit complex that includes other components involving lysine acetyltransferase(KAT)6A/6B/7.Brpf1,KAT6A,and KAT6B mutations were identified as the causal genes of neurodevelopmental disorders leading to intellectual disability.Our previous work revealed strong and specific expression of Brpf1 in both the postnatal and adult forebrain,especially the hippocampus,which has essential roles in learning and memory.Here,we hypothesized that Brpf1 plays critical roles in the function of forebrain excitatory neurons,and that its deficiency leads to learning and memory deficits.To test this,we knocked out Brpf1 in forebrain excitatory neurons using CaMKIIa-Cre.We found that Brpf1 deficiency reduced the frequency of miniature excitatory postsynaptic currents and downregulated the expression of genes Pcdhgb1,Slc16a7,Robo3,and Rho,which are related to neural development,synapse function,and memory,thereby damaging spatial and fear memory in mice.These findings help explain the mechanisms of intellectual impairment in patients with BRPF1 mutation.展开更多
Parkinson's disease(PD)is a progressive neurodegenerative disorder with clinical symptoms of involuntary or uncontrollable movements such as tremors,rigidity,and incoordination.The learning deficit is largely over...Parkinson's disease(PD)is a progressive neurodegenerative disorder with clinical symptoms of involuntary or uncontrollable movements such as tremors,rigidity,and incoordination.The learning deficit is largely overlooked in the past because it is generally less impaired in the early stages of PD than in Alzheimer's disease.展开更多
文摘植物性系统多样性对森林群落构建和生态系统功能维持具有重要意义。本文以浙江百山祖亚热带森林25 ha动态监测样地中胸径(diameter at breast height,DBH)≥1 cm的木本植物为研究对象,描述了样地内木本植物性系统多样性的格局,并检验了地形、土壤理化性质和演替对群落性系统数量特征的影响。结果表明:(1)样地内163种木本种子植物中有两性花植物95种,雌雄异株植物43种,雌雄同株异花植物25种,两性花在科、属、种和个体水平上的数量都占据优势;雌雄同株异花植物的平均胸径显著大于两性花和雌雄异株植物。(2)在样方水平,两性花植物数量同样占据主要优势,其次为雌雄异株植物和雌雄同株异花植物;在样地内,较高海拔的北坡性系统多样性较低,而较低海拔的南坡性系统多样性较高。(3)地形对植物群落性系统数量特征的影响大于理化因子;演替阶段同样对性系统数量特征具有重要影响,在演替早期物种黄山松(Pinus taiwanensis)和杉木(Cunninghamialanceolata)比例较高的样方中雌雄异株植物出现的频率更高,并因此具有更高的性系统多样性。本研究结果表明:植物性系统在森林群落构建过程中发挥重要作用,且地形、演替和土壤理化性质会共同塑造森林群落性系统多样性格局。
基金supported by the National Natural Science Foundation of China,No. 81771228Shanghai Association of Science and Technology,Nos. 22WZ2501700 and 23WZ2504500 (all to LY)
文摘Bromodomain and plant homeodomain(PHD)finger containing protein 1(Brpf1)is an activator and scaffold protein of a multiunit complex that includes other components involving lysine acetyltransferase(KAT)6A/6B/7.Brpf1,KAT6A,and KAT6B mutations were identified as the causal genes of neurodevelopmental disorders leading to intellectual disability.Our previous work revealed strong and specific expression of Brpf1 in both the postnatal and adult forebrain,especially the hippocampus,which has essential roles in learning and memory.Here,we hypothesized that Brpf1 plays critical roles in the function of forebrain excitatory neurons,and that its deficiency leads to learning and memory deficits.To test this,we knocked out Brpf1 in forebrain excitatory neurons using CaMKIIa-Cre.We found that Brpf1 deficiency reduced the frequency of miniature excitatory postsynaptic currents and downregulated the expression of genes Pcdhgb1,Slc16a7,Robo3,and Rho,which are related to neural development,synapse function,and memory,thereby damaging spatial and fear memory in mice.These findings help explain the mechanisms of intellectual impairment in patients with BRPF1 mutation.
基金supported by the STI 2030-Major Projects,No.2021ZD0200500the Natural Science Foundation of Shanghai,No.21ZR1419700(both to SL)。
文摘Parkinson's disease(PD)is a progressive neurodegenerative disorder with clinical symptoms of involuntary or uncontrollable movements such as tremors,rigidity,and incoordination.The learning deficit is largely overlooked in the past because it is generally less impaired in the early stages of PD than in Alzheimer's disease.
