Objective: To explore the application effect of flipped classroom combined with problem-based learning teaching method in clinical skills teaching of standardized training for resident doctors of traditional Chinese M...Objective: To explore the application effect of flipped classroom combined with problem-based learning teaching method in clinical skills teaching of standardized training for resident doctors of traditional Chinese Medicine. Methods: The study used the experimental control method. The study lasted from September to November 2022. The subjects of this study were 49 students of standardized training for resident doctors of traditional Chinese Medicine from grades 2020, 2021 and 2022 of Dazhou integrated TCM & Western Medicine Hospital. They were randomly divided into experiment group (25) and control group (24). The experiment group adopted flipped classroom combined with problem-based learning teaching method, and the control group adopted traditional teaching method. The teaching content was 4 basic clinical skill projects, including four diagnoses of traditional Chinese Medicine, cardiopulmonary resuscitation, dressing change procedure, acupuncture and massage. The evaluation method was carried out by comparing the students’ performance and a self-designed questionnaire was used to investigate the students’ evaluation of the teaching method. Results: The test scores of total scores in the experimental group (90.12 ± 5.89) were all higher than those in the control group (81.47 ± 7.96) (t = 4.53, P P Conclusions: The teaching process of the flipped classroom combined with problem-based learning teaching method is conducive to improving the efficiency of classroom teaching, cultivating students’ self-learning ability, and enhancing students’ willingness to learn.展开更多
Ion-solvaing membranes(ISMs)have received extensive attention in recent years as a key component in electrochemical energy conversion and storage devices.This article provides an overview of structural composition,per...Ion-solvaing membranes(ISMs)have received extensive attention in recent years as a key component in electrochemical energy conversion and storage devices.This article provides an overview of structural composition,performance advan-tages,research progress,ion conduction mechanism and existing issues of ISMs,primarily classifying them according to the matrix structure.A detailed analysis of performance enhancement methods,key performance indicators of ISMs and performance influencing factors is also presented.The article contributes to further optimizing the design and application of ion-solvation membranes,providing theoretical support for the development of fields such as hydrogen production through electrolysis of water and electrochemical energy in the future.展开更多
目的系统评价中医外治法治疗子宫腺肌病(AM)的有效性与安全性。方法检索建库至2024年11月中国知网、万方数据库、中国生物医学文献数据库、Pub Med、Web of Science中所有关于中医外治法治疗AM的随机对照试验(RCTs),采用Rev Man 5.4.1...目的系统评价中医外治法治疗子宫腺肌病(AM)的有效性与安全性。方法检索建库至2024年11月中国知网、万方数据库、中国生物医学文献数据库、Pub Med、Web of Science中所有关于中医外治法治疗AM的随机对照试验(RCTs),采用Rev Man 5.4.1软件进行Meta分析。结果纳入文献19篇,总样本量1474例,试验组740例,对照组734例。Meta分析结果显示,与对照组比较,中医外治法可显著提高临床总有效率(OR=3.09,95%CI:1.69~5.67,P=0.0003),改善患者视觉模拟评分法(VAS)评分[均数差(MD)=-1.56,95%CI:-2.47~-0.65,P=0.0008]、痛经程度积分[标准化均数差(SMD)=-0.50,95%CI:-0.94~-0.05,P=0.03]、月经量(SMD=-1.18,95%CI:-1.83~-0.53,P=0.0004)、血清糖类抗原125(CA125)水平(MD=-12.01,95%CI:-15.97~-8.04,P<0.00001)及子宫体积(MD=-17.10,95%CI:-24.49~-9.70,P<0.00001),不良反应发生率(OR=0.18,95%CI:0.09~0.35,P<0.00001)低于对照组。结论中医外治法治疗AM临床疗效显著,不良反应较少。展开更多
Graphite,encompassing both natural graphite and synthetic graphite,and graphene,have been extensively utilized and investigated as anode materials and additives in lithium-ion batteries(LIBs).In the pursuit of carbon ...Graphite,encompassing both natural graphite and synthetic graphite,and graphene,have been extensively utilized and investigated as anode materials and additives in lithium-ion batteries(LIBs).In the pursuit of carbon neutrality,LIBs are expected to play a pivotal role in reducing CO_(2)emissions by decreasing reliance on fossil fuels and enabling the integration of renewable energy sources.Owing to their technological maturity and exceptional electrochemical performance,the global production of graphite and graphene for LIBs is projected to continue expanding.Over the past decades,numerous researchers have concentrated on reducing the material and energy input whilst optimising the electrochemical performance of graphite and graphene,through novel synthesis methods and various modifications at the laboratory scale.This review provides a comprehensive examination of the manufacturing methods,environmental impact,research progress,and challenges associated with graphite and graphene in LIBs from an industrial perspective,with a particular focus on the carbon footprint of production processes.Additionally,it considers emerging challenges and future development directions of graphite and graphene,offering significant insights for ongoing and future research in the field of green LIBs.展开更多
Objective To determine whether frailty is a risk factor for hospitalization and mortality in older adults enrolled in the "Chronic Heart Failure Program" at a hospital in Lima, Peru, between 2018–2021.Metho...Objective To determine whether frailty is a risk factor for hospitalization and mortality in older adults enrolled in the "Chronic Heart Failure Program" at a hospital in Lima, Peru, between 2018–2021.Methods This was an ambispective cohort study. A total of 85 older adults participating in the Chronic Heart Failure Program at Guillermo Almenara National Hospital were included. Each had an initial frailty assessment, forming two cohorts: frail and non-frail older adults. Medical records were reviewed, and patients were followed for one year to track events of interest(hospitalization and mortality). Overall survival and risk factors for hospitalization and death were determined.Results During follow-up, 15.3% of the older adults died, and frailty was identified in 58.8% of the patients. Overall survival using the Kaplan-Meier method was 96.5% at 3 months after entering the Chronic Heart Failure Program;92.9% at 6 months;and85.9% at one year. Multivariate analysis using Poisson regression found that frailty was not a risk factor for hospitalization(a RR =0.92;95% CI: 0.42–2.03). Survival analysis using the Cox proportional hazards model showed that frailty was also not a risk factor for mortality after one year of follow-up(a HR = 1.32;95% CI: 0.27–6.53).Conclusions Our research does not confirm frailty as a risk factor for hospitalization or mortality in older adults enrolled in the“Chronic Heart Failure Program” after one year of follow-up.展开更多
文摘Objective: To explore the application effect of flipped classroom combined with problem-based learning teaching method in clinical skills teaching of standardized training for resident doctors of traditional Chinese Medicine. Methods: The study used the experimental control method. The study lasted from September to November 2022. The subjects of this study were 49 students of standardized training for resident doctors of traditional Chinese Medicine from grades 2020, 2021 and 2022 of Dazhou integrated TCM & Western Medicine Hospital. They were randomly divided into experiment group (25) and control group (24). The experiment group adopted flipped classroom combined with problem-based learning teaching method, and the control group adopted traditional teaching method. The teaching content was 4 basic clinical skill projects, including four diagnoses of traditional Chinese Medicine, cardiopulmonary resuscitation, dressing change procedure, acupuncture and massage. The evaluation method was carried out by comparing the students’ performance and a self-designed questionnaire was used to investigate the students’ evaluation of the teaching method. Results: The test scores of total scores in the experimental group (90.12 ± 5.89) were all higher than those in the control group (81.47 ± 7.96) (t = 4.53, P P Conclusions: The teaching process of the flipped classroom combined with problem-based learning teaching method is conducive to improving the efficiency of classroom teaching, cultivating students’ self-learning ability, and enhancing students’ willingness to learn.
基金supported by the National Key Research and Development Program of China (2022YFE0138900)the “Scientific and Technical Innovation Action Plan” Basic Research Field of Shanghai Science and Technology Committee (19JC1410500)。
文摘Ion-solvaing membranes(ISMs)have received extensive attention in recent years as a key component in electrochemical energy conversion and storage devices.This article provides an overview of structural composition,performance advan-tages,research progress,ion conduction mechanism and existing issues of ISMs,primarily classifying them according to the matrix structure.A detailed analysis of performance enhancement methods,key performance indicators of ISMs and performance influencing factors is also presented.The article contributes to further optimizing the design and application of ion-solvation membranes,providing theoretical support for the development of fields such as hydrogen production through electrolysis of water and electrochemical energy in the future.
文摘目的系统评价中医外治法治疗子宫腺肌病(AM)的有效性与安全性。方法检索建库至2024年11月中国知网、万方数据库、中国生物医学文献数据库、Pub Med、Web of Science中所有关于中医外治法治疗AM的随机对照试验(RCTs),采用Rev Man 5.4.1软件进行Meta分析。结果纳入文献19篇,总样本量1474例,试验组740例,对照组734例。Meta分析结果显示,与对照组比较,中医外治法可显著提高临床总有效率(OR=3.09,95%CI:1.69~5.67,P=0.0003),改善患者视觉模拟评分法(VAS)评分[均数差(MD)=-1.56,95%CI:-2.47~-0.65,P=0.0008]、痛经程度积分[标准化均数差(SMD)=-0.50,95%CI:-0.94~-0.05,P=0.03]、月经量(SMD=-1.18,95%CI:-1.83~-0.53,P=0.0004)、血清糖类抗原125(CA125)水平(MD=-12.01,95%CI:-15.97~-8.04,P<0.00001)及子宫体积(MD=-17.10,95%CI:-24.49~-9.70,P<0.00001),不良反应发生率(OR=0.18,95%CI:0.09~0.35,P<0.00001)低于对照组。结论中医外治法治疗AM临床疗效显著,不良反应较少。
基金supported by European Union's Horizon Europe,UK Research and Innovation(UKRI).
文摘Graphite,encompassing both natural graphite and synthetic graphite,and graphene,have been extensively utilized and investigated as anode materials and additives in lithium-ion batteries(LIBs).In the pursuit of carbon neutrality,LIBs are expected to play a pivotal role in reducing CO_(2)emissions by decreasing reliance on fossil fuels and enabling the integration of renewable energy sources.Owing to their technological maturity and exceptional electrochemical performance,the global production of graphite and graphene for LIBs is projected to continue expanding.Over the past decades,numerous researchers have concentrated on reducing the material and energy input whilst optimising the electrochemical performance of graphite and graphene,through novel synthesis methods and various modifications at the laboratory scale.This review provides a comprehensive examination of the manufacturing methods,environmental impact,research progress,and challenges associated with graphite and graphene in LIBs from an industrial perspective,with a particular focus on the carbon footprint of production processes.Additionally,it considers emerging challenges and future development directions of graphite and graphene,offering significant insights for ongoing and future research in the field of green LIBs.
文摘Objective To determine whether frailty is a risk factor for hospitalization and mortality in older adults enrolled in the "Chronic Heart Failure Program" at a hospital in Lima, Peru, between 2018–2021.Methods This was an ambispective cohort study. A total of 85 older adults participating in the Chronic Heart Failure Program at Guillermo Almenara National Hospital were included. Each had an initial frailty assessment, forming two cohorts: frail and non-frail older adults. Medical records were reviewed, and patients were followed for one year to track events of interest(hospitalization and mortality). Overall survival and risk factors for hospitalization and death were determined.Results During follow-up, 15.3% of the older adults died, and frailty was identified in 58.8% of the patients. Overall survival using the Kaplan-Meier method was 96.5% at 3 months after entering the Chronic Heart Failure Program;92.9% at 6 months;and85.9% at one year. Multivariate analysis using Poisson regression found that frailty was not a risk factor for hospitalization(a RR =0.92;95% CI: 0.42–2.03). Survival analysis using the Cox proportional hazards model showed that frailty was also not a risk factor for mortality after one year of follow-up(a HR = 1.32;95% CI: 0.27–6.53).Conclusions Our research does not confirm frailty as a risk factor for hospitalization or mortality in older adults enrolled in the“Chronic Heart Failure Program” after one year of follow-up.
