In the mid-21st century,natural gas will enter its golden age,and the era of natural gas is arriving.This paper reviews the development stages of global natural gas industry and the enlightenment of American shale gas...In the mid-21st century,natural gas will enter its golden age,and the era of natural gas is arriving.This paper reviews the development stages of global natural gas industry and the enlightenment of American shale gas revolution,summarizes the development history and achievements of the natural gas industry in China,analyzes the status and challenges of natural gas in the green and low-carbon energy transition,and puts forward the natural gas industry development strategies under carbon neutral target in China.The natural gas industry in China has experienced three periods:start,growth,and leap forward.At present,China has become the fourth largest natural gas producer and third largest natural gas consumer in the world,and has made great achievements in natural gas exploration and development theory and technology,providing important support for the growth of production and reserves.China has set its goal of carbon neutrality to promote green and sustainable development,which brings opportunities and challenges for natural gas industry.Natural gas has significant low-carbon advantages,and gas-electric peak shaving boosts new energy development;the difficulty and cost of development are more prominent.For the national energy security and harmonious development between economy and ecology under the carbon neutral goal,based on the principle of"comprehensive planning,technological innovation,multi-energy complementarity,diversified integration,flexibility and efficiency,optimization and upgrading",the construction of the production-supplystorage-marketing system has to be improved so as to boost the development of the natural gas industry.First,it is necessary to strengthen efforts in the exploration and development of natural gas,making projects and arrangement in key exploration and development areas,meanwhile,it is urgent to make breakthroughs in key science theories and technologies,so as to increase reserve and production.Second,it should promote green and innovative development of the natural gas by developing new techniques,expanding new fields and integrating with new energy.Third,there is a demand to realize transformation and upgrading of the supply and demand structure of natural gas by strengthening the layout of pipeline gas,liquefied natural gas and the construction of underground gas storage,establishing reserve system for improving abilities of emergency response and adjustment,raising the proportion of natural gas in the primary energy consumption and contributing to the transformation of energy consumption structure,realizing low-carbon resources utilization and clean energy consumption.展开更多
The oceans'vast expanse has given rise to copious oil and gas resources,with recent years witnessing a steady unlocking of offshore oil and gas potential,positioning them as a key successor in global energy reserv...The oceans'vast expanse has given rise to copious oil and gas resources,with recent years witnessing a steady unlocking of offshore oil and gas potential,positioning them as a key successor in global energy reserves.Currently,offshore oil and gas extraction constitutes nearly a third of the world's oil and gas output.This segment has evolved into a mutually beneficial ecosystem where operators and service providers collaborate closely around exploration and development activities.Investment in offshore oil and gas typically follows a dual "one-third’"pattern,reflecting high upfront costs but promising returns.It also underscores the stark variations in project viability and regional economic efficiency,with monopolistic traits seen at both national and corporate levels.Collaboration has emerged as a key tactic for resource-rich countries and oil companies to advance their offshore ventures.Given the distinct nature of offshore oil and gas development,Chinese oil companies are advised to seize opportunities in marine exploration,emphasize the coordination and planning abilities of the global supply chain,focus on the reserves of offshore oil and gas development technologies,as well as the capabilities of commercial talents and other forms of support,courageously pursue significant offshore assets,and effectively utilize global technology,equipment,and expertise,and rapidly build a competitive edge in offshore oil and gas projects.展开更多
The Fushan Depression is one of the petroliferous depressions in the Beibuwan Basin,South China Sea.Previous studies have preliminarily explored the origin and source of crude oils in some areas of this depression.Nev...The Fushan Depression is one of the petroliferous depressions in the Beibuwan Basin,South China Sea.Previous studies have preliminarily explored the origin and source of crude oils in some areas of this depression.Nevertheless,no systematic investigations on the classification and origin of oils and hy-drocarbon migration processes have been made for the entire petroleum system in this depression,which has significantly hindered the hydrocarbon exploration in the region.A total of 32 mudstone and 58 oil samples from the Fushan Depression were analyzed to definite the detailed oil-source correlation within the sequence and sedimentary framework.The organic matter of third member of Paleogene Liushagang Formation(Els(3))source rocks,both deltaic and lacustrine mudstone,are algal-dominated with high abundance of C_(23)tricyclic terpane and C_(30)4-methylsteranes.The deltaic source rocks occur-ring in the first member(Els_(1))and second member(Els_(2))of the Paleogene Liushagang Formation are characterized by high abundance of C_(19+20)tricyclic terpane and oleanane,reflecting a more terrestrial plants contribution.While lacustrine source rocks of Els_(1)and Els_(2)display the reduced input of terrige-nous organic matter with relatively low abundance of C 19+20 tricyclic terpane and oleanane.Three types of oils were identified by their biomarker compositions in this study.Most of the oils discovered in the Huachang and Bailian Els_(1)reservoir belong to group A and were derived from lacustrine source rocks of Els_(1)and Els_(2).Group B oils are found within the Els_(1)and Els_(2)reservoirs,showing a close relation to the deltaic source rocks of Els_(1)and Els_(2),respectively.Group C oils,occurring in the Els3 reservoirs,have a good affinity with the Els3 source rocks.The spatial distribution and accumulation of different groups of oils are mainly controlled by the sedimentary facies and specific structural conditions.The Els_(2)reservoir in the Yong'an area belonging to Group B oil,are adjacent to the source kitchen and could be considered as the favorable exploration area in the future.展开更多
By systematically reviewing the development status of global carbon dioxide capture,utilization and storage(CCUS)cluster,and comparing domestic and international CCUS industrial models and successful experiences,this ...By systematically reviewing the development status of global carbon dioxide capture,utilization and storage(CCUS)cluster,and comparing domestic and international CCUS industrial models and successful experiences,this study explores the challenges and strategies for the scaled development of the CCUS industry of China.Globally,the CCUS industry has entered a phase of scaled and clustered development.North America has established a system of key technologies in large-scale CO_(2) capture,long-distance pipeline transmission,pipeline network optimization,and large-scale CO_(2) flooding for enhanced oil recovery(CO_(2)-EOR),with relatively mature cluster development and a gradual shift in industrial model from CO_(2)-EOR to geological storage.The CCUS industry of China has developed rapidly across all segments but remains in the early stage of cluster development,facing challenges such as absent business model,insufficient policy support,and technological gaps in core areas.China needs to improve the policy support system to boost enterprises participation across the entire industrial chain,strengthen top-level design and medium-to long-term planning to accelerate demonstration projects construction for whole-process CCUS clusters,advance for a full-chain technological system,including low-cost capture,pipeline optimization and EOR/storage integration technologies,and strengthen personnel training,strengthen discipline construction and university-enterprise research cooperation.展开更多
In this work,Langevin dynamics simulations were carried out to thoroughly investigate the swapping process of composite knots under tension in a cuboid nanochannel.From our analysis,the free energy profiles of knot sw...In this work,Langevin dynamics simulations were carried out to thoroughly investigate the swapping process of composite knots under tension in a cuboid nanochannel.From our analysis,the free energy profiles of knot swapping under different conditions were extracted from the overall probability distribution of the relative distance between the centers of composite knots.In addition,the impact of the stretching force,confinement size,and bending stiffness on the free energy profiles was directly identified.Especially,the influence of topology structure is for the first time reported.The increasing stretching force in a fixed confinement or the confinement size under a constant stretching force does not alter their respective equilibrium populations at the separate state and the entangled state.In contrast,a bending stiffness larger than 15 enhanced the formation of the entangled state.The topology structure of the 51knot,which was different from the 52knot,resulted in forming a metastable state in the free energy profiles.The increasing stretching forces yielded an enhancement of the following free energy barrier.展开更多
Deep rock is under a complex geological environment with high geo-stress, high pore pressure, and strong dynamic disturbance. Understanding the dynamic response of rocks under coupled hydraulic-mechanical loading is t...Deep rock is under a complex geological environment with high geo-stress, high pore pressure, and strong dynamic disturbance. Understanding the dynamic response of rocks under coupled hydraulic-mechanical loading is thus essential in evaluating the stability and safety of subterranean engineering structures. Nevertheless, the constraints in experimental techniques have led to limited prior investigations into the dynamic compression behavior of rocks subjected to simultaneous high in-situ stress and pore pressure conditions. This study utilizes a triaxial split Hopkinson pressure bar (SHPB) system in conjunction with a pore pressure loading cell to conduct dynamic experiments on rocks subjected to hydraulic-mechanical loading. A porous green sandstone (GS) was adopted as the testing rock material. The findings reveal that the dynamic behavior of rock specimens is significantly influenced by multiple factors, including the loading rate, confining stress, and pore pressure. Specifically, the dynamic compressive strength of GS exhibits an increase with higher loading rates and greater confining pressures, while it decreases with elevated pore pressure. Moreover, the classical Ashby-Sammis micromechanical model was augmented to account for dynamic loading and pore pressure considerations. By deducing the connection between crack length and damage evolution, the resulting law of crack expansion rate is related to the strain rate. In addition, the influence of hydraulic factors on the stress intensity factor at the crack tip is introduced. Thereby, a dynamic constitutive model for deep rocks under coupled hydraulic-mechanical loading was established and then validated against the experimental results. Subsequently, the characteristics of introduced parameter for quantifying the water-induced effects were carefully discussed.展开更多
The ultra-deep(deeper than 8000 m)petroleum in the platform-basin zones of the Tarim Basin has been found mainly in the Lower Paleozoic reservoirs located to the east of the strike-slip fault F5 in the north depressio...The ultra-deep(deeper than 8000 m)petroleum in the platform-basin zones of the Tarim Basin has been found mainly in the Lower Paleozoic reservoirs located to the east of the strike-slip fault F5 in the north depression.However,the source and exploration potential of the ultra-deep petroleum in the Cambrian on the west of F5 are still unclear.Through the analysis of lithofacies and biomarkers,it is revealed that there are at least three kinds of isochronous source rocks(SRs)in the Cambrian Newfoundland Series in Tarim Basin,which were deposited in three sedimentary environments,i.e.sulfide slope,deep-water shelf and restricted bay.In 2024,Well XT-1 in the western part of northern Tarim Basin has yielded a high production of condensate from the Cambrian.In the produced oil,entire aryl-isoprenoid alkane biomarkers were detected,but triaromatic dinosterane was absent.This finding is well consistent with the geochemical characteristics of the Newfoundland sulfidized slope SRs represented by those in wells LT-1 and QT-1,suggesting that the Newfoundland SRs are the main source of the Cambrian petroleum discovered in Well XT-1.Cambrian crude oil of Well XT-1 also presents the predominance of C29 steranes and is rich in long-chain tricyclic terpanes(up to C39),which can be the indicators for effectively distinguishing lithofacies such as siliceous mudstone and carbonate rock.Combined with the analysis of hydrocarbon accumulation in respect of conduction systems including thrust fault and strike-slip fault,it is found that the area to the west of F5 is possible to receive effective supply of hydrocarbons from the Cambrian Newfoundland SRs in Manxi hydrocarbon-generation center.This finding suggests that the area to the west of F5 will be a new target of exploration in the Cambrian ultra-deep structural-lithologic reservoirs in the Tarim Basin,in addition to the Cambrian ultra-deep platform-margin facies-controlled reservoirs in the eastern part of the basin.展开更多
Human interaction with natural environments is gaining increasing attention in environmental sciences as research consistently shows that access to green spaces,clean air,and biodiversity plays a crucial role in enhan...Human interaction with natural environments is gaining increasing attention in environmental sciences as research consistently shows that access to green spaces,clean air,and biodiversity plays a crucial role in enhancing physical health,reducing stress,and improving overall well-being.This study conducts a bibliometric and visualization-based analysis of forest therapy research,emphasizing its physiological and psychological benefits.Using the Web of Science database,we identified and analyzed 414 studies from 1998 to 2023.Through CiteSpace and VOSviewer,we mapped these documents to examine research trends,publication networks,leading scholars and institutions,key journals,and thematic evolution.Findings indicate that forest therapy research is predominantly concentrated in East Asia,North America,Australia,and Europe,with strong collaborative networks among authors and institutions.The concentration of publications,research evolution,and keyword trends reflect the development of forest therapy research.The analysis further identifies sixteen research clusters and discusses two research themes:physiological and psychological effects.By analyzing how the natural environment contributes to human well-being,we provide a comprehensive and visually structured understanding of forest therapy as an intersection of environmental science,public health and well-being,and ecosystem conservation.Our findings offer a new perspective for future interdisciplinary research,emphasizing the need for well-designed clinical trials to substantiate forest therapy’s diverse health effects and its role in promoting sustainable interactions between human societies and natural environments.展开更多
By integrating core observations,logging data and seismic interpretation,this study takes the massive Cretaceous carbonates in the M block of the Santos Basin,Brazil,as an example to establish the sequence filling pat...By integrating core observations,logging data and seismic interpretation,this study takes the massive Cretaceous carbonates in the M block of the Santos Basin,Brazil,as an example to establish the sequence filling pattern of fault-bounded isolated platforms in rift lake basins,reveal the control mechanisms of shoal-body development and reservoir formation,and reconstruct the evolutionary history of lithofacies paleogeography.The following results are obtained.(1)Three tertiary sequences(SQ1-SQ3)are identified in the Lower Cretaceous Itapema-Barra Velha of the M block.During the depositional period of SQ1,the rift basement faults controlled the stratigraphic distribution pattern of thick on both sides and thin in the middle.The strata overlapped to uplift in the early stage.During the depositional period of SQ2-SQ3,the synsedimentary faults controlled the paleogeomorphic reworking process with subsidence in the northwest and uplifting in the northeast,accompanied with the relative fall of lake level.(2)The Lower Cretaceous in the M block was deposited in a littoral-shallow lake,with the lithofacies paleogeographic pattern transiting from the inner clastic shoals and outer shelly shoals in SQ1 to the alternation of mounds and shoals in SQ2-SQ3.(3)Under the joint control of relative lake-level fluctuation,synsedimentary faults and volcanic activity,the shelly shoals in SQ1 tend to accumulated vertically in the raised area,and the mound-shoal complex in SQ2-SQ3 tends to migrate laterally towards the slope-break belt due to the reduction of accommodation space.(4)The evolution pattern of high-energy mounds and shoals,which were vertically accumulated in the early stage and laterally migrated in the later stage,controlled the transformation of high-quality reservoirs from“centralized”to“ring shaped”distribution.The research findings clarify the sedimentary patterns of mounds and shoals and the distribution of favorable reservoirs in the fault-controlled lacustrine isolated platform,providing support for the deepwater hydrocarbon exploration in the subsalt carbonate rocks in the Santos Basin.展开更多
Field development practices in many shale gas regions(e.g.,the Changning region)have revealed a persistent issue of suboptimal reserve utilization,particularly in areas where the effective drainage width of production...Field development practices in many shale gas regions(e.g.,the Changning region)have revealed a persistent issue of suboptimal reserve utilization,particularly in areas where the effective drainage width of production wells is less than half the inter-well spacing(typically 400-500 m).To address this,infill drilling has become a widely adopted and effective strategy for enhancing reservoir contact andmobilizing previously untapped reserves.However,this approach has introduced significant inter-well interference,complicating production dynamics and performance evaluation.The two primary challenges hindering efficient deployment of infill wells are:(1)the quantitative assessment of hydraulic and pressure connectivity between infill wells and their associated parent wells,and(2)the accurate estimation of platform-scale Estimated Ultimate Recovery(EUR)following infill implementation.This study presents a novel framework to quantify inter-well connectivity by deriving a material balance equation tailored for shale gas infill well groups,explicitly incorporating gas adsorption and desorption mechanisms.The model simultaneously evaluates formation pressure evolution and crossflow behavior between wells,offering a robust analytical basis for performance prediction.For infill wells intersecting the drainage boundaries of parent wells,EUR is estimated using an analytical model developed for multi-stage hydraulically fractured horizontal wells.Meanwhile,the EUR of the parent wells is obtained by summing their pre-infill EUR with the final inter-well crossflow contribution.展开更多
Mineral identification is foundational to geological survey research,mineral resource exploration,and mining engineering.Considering the diversity of mineral types and the challenge of achieving high recognition accur...Mineral identification is foundational to geological survey research,mineral resource exploration,and mining engineering.Considering the diversity of mineral types and the challenge of achieving high recognition accuracy for similar features,this study introduces a mineral detection method based on YOLOv8-SBI.This work enhances feature extraction by integrating spatial pyramid pooling-fast(SPPF)with the simplified self-attention module(SimAM),significantly improving the precision of mineral feature detection.In the feature fusion network,a weighted bidirectional feature pyramid network is employed for advanced cross-channel feature integration,effectively reducing feature redundancy.Additionally,Inner-Intersection Over Union(InnerIOU)is used as the loss function to improve the average quality localization performance of anchor boxes.Experimental results show that the YOLOv8-SBI model achieves an accuracy of 67.9%,a recall of 74.3%,a mAP@0.5 of 75.8%,and a mAP@0.5:0.95 of 56.7%,with a real-time detection speed of 244.2 frames per second.Compared to YOLOv8,YOLOv8-SBI demonstrates a significant improvement with 15.4%increase in accuracy,28.5%increase in recall,and increases of 28.1%and 20.9%in mAP@0.5 and mAP@0.5:0.95,respectively.Furthermore,relative to other models,such as YOLOv3,YOLOv5,YOLOv6,YOLOv8,YOLOv9,and YOLOv10,YOLOv8-SBI has a smaller parameter size of only 3.01×10^(6).This highlights the optimal balance between detection accuracy and speed,thereby offering robust technical support for intelligent mineral classification.展开更多
Aornial mealnocarpa Elliot is a rare tree species that combined edible,medicinal,ornamental and ecological values. This article analyzes the economic value,domestic research and development status and development tren...Aornial mealnocarpa Elliot is a rare tree species that combined edible,medicinal,ornamental and ecological values. This article analyzes the economic value,domestic research and development status and development trend of A. mealnocarpa. Heilongjiang Province has been hurried to introduce A. mealnocarpa,lack of understanding of the characteristics of the tree species,resulting in serious cold damage and great economic losses. For these issues,proposals are put forward to promote the development of A. mealnocarpa planting industry.展开更多
With the consideration of slip deformation mechanism and various slip systems of body centered cubic （BCC） metals, Taylor-type and finite element polycrystal models were embedded into the commercial finite element c...With the consideration of slip deformation mechanism and various slip systems of body centered cubic （BCC） metals, Taylor-type and finite element polycrystal models were embedded into the commercial finite element code ABAQUS to realize crystal plasticity finite element modeling, based on the rate dependent crystal constitutive equations. Initial orientations measured by electron backscatter diffraction （EBSD） were directly input into the crystal plasticity finite element model to simulate the develop- ment of rolling texture of interstitial-free steel （IF steel） at various reductions. The modeled results show a good agreement with the experimental results. With increasing reduction, the predicted and experimental rolling textures tend to sharper, and the results simulated by the Taylor-type model are stronger than those simulated by finite element model.＇Conclusions are obtained that rolling textures calculated with 48 { 110} 〈 111 〉＋ { 112 } 〈 111〉＋ { 123 } 〈 111 〉 slip systems are more approximate to EBSD results.展开更多
With the booming development over the past years,geo-parks have achieved impressive progress together with a series of problems.Most importantly,geological tourism is not in prosperity.How to prosper geological touris...With the booming development over the past years,geo-parks have achieved impressive progress together with a series of problems.Most importantly,geological tourism is not in prosperity.How to prosper geological tourism and achieve the sustainable development of geoparks is the top concern of workers engaged in tourism geology in China.This article discusses the problem from the perspective of core competitiveness of geo-parks,particularly from three aspects of subject,object and medium,and puts forward methods to form the core competitiveness.展开更多
1 Introduction Now, the key of oil-field＇s increase production is the development technology for extra-low permeability reservoirs whose porosity is less than 5% and permeability less than 5 mD. The technologies of h...1 Introduction Now, the key of oil-field＇s increase production is the development technology for extra-low permeability reservoirs whose porosity is less than 5% and permeability less than 5 mD. The technologies of horizontal well, fracturing and gas driving are the advanced means of improving recovery.展开更多
The field data of shale fracturing demonstrate that the flowback performance of fracturing fluid is different from that of conventional reservoirs,where the flowback rate of shale fracturing fluid is lower than that o...The field data of shale fracturing demonstrate that the flowback performance of fracturing fluid is different from that of conventional reservoirs,where the flowback rate of shale fracturing fluid is lower than that of conventional reservoirs.At the early stage of flowback,there is no single-phase flow of the liquid phase in shale,but rather a gas-water two-phase flow,such that the single-phase flow model for tight oil and gas reservoirs is not applicable.In this study,pores and microfractures are extracted based on the experimental results of computed tomography(CT)scanning,and a spatial model of microfractures is established.Then,the influence of rough microfracture surfaces on the flow is corrected using the modified cubic law,which was modified by introducing the average deviation of the microfracture height as a roughness factor to consider the influence of microfracture surface roughness.The flow in the fracture network is simulated using the modified cubic law and the lattice Boltzmann method(LBM).The results obtained demonstrate that most of the fracturing fluid is retained in the shale microfractures,which explains the low fracturing fluid flowback rate in shale hydraulic fracturing.展开更多
Natural gas hydrates,intricate crystalline structures formed by water molecules and small gas molecules,have emerged as a significant and globally impactful clean energy resource.However,their commercial exploitation ...Natural gas hydrates,intricate crystalline structures formed by water molecules and small gas molecules,have emerged as a significant and globally impactful clean energy resource.However,their commercial exploitation faces challenges,particularly operational disruptions caused by sand-related blockages.Understanding the rheological properties of hydrate slurry,especially in the presence of micron-sized sand particles,is imperative for ensuring the flow assurance of subsea hydrate exploitation.This study extensively investigates the rheological properties of sand-containing hydrate slurries.The findings reveal that these slurries exhibit non-Newtonian fluid characteristics,including yield stress,thixotropy,and shear-thinning behavior.Solid-like elastic features are observed in sand-containing hydrate slurries before yielding,transitioning to viscous behavior after yielding.Even with a minimal amount of sand,both static yield stress and yield strain experience substantial changes,correlating with the increase in sand concentration.The research conclusively establishes the thixotropic nature of sand-hydrate slurries,where the viscosity decay rate is directly influenced by the shear rate.These insights aim to contribute comprehensively to the development of effective flow assurance strategies,ensuring the safe and stable operation of subsea hydrate exploitation.展开更多
The deep earth,deep sea,and deep space are the main parts of the national“three deep”strategy,which is in the forefront of the strategic deployment clearly defined in China’s 14th Five-Year Plan(2021-2025)and the L...The deep earth,deep sea,and deep space are the main parts of the national“three deep”strategy,which is in the forefront of the strategic deployment clearly defined in China’s 14th Five-Year Plan(2021-2025)and the Long-Range Objectives Through the Year 2035.It is important to reveal the evolutionary process and mechanism of deep tectonics to understand the earth’s past,present and future.The academic con-notation of Geology in Time has been given for the first time,which refers to the multi-field evolution response process of geological bodies at different time and spatial scales caused by geological processes inside and outside the Earth.Based on the deep in situ detection space and the unique geological envi-ronment of China Jinping Underground Laboratory,the scientific issue of the correlation mechanism and law between deep internal time-varying and shallow geological response is given attention.Innovative research and frontier exploration on deep underground in situ geo-information detection experiments for Geology in Time are designed to be carried out,which will have the potential to explore the driving force of Geology in Time,reveal essential laws of deep earth science,and explore innovative technologies in deep underground engineering.展开更多
This study introduces a novel method integrating CO_(2)flooding with radial borehole fracturing for enhanced oil recovery and CO_(2)underground storage,a solution to the limited vertical stimulation reservoir volume i...This study introduces a novel method integrating CO_(2)flooding with radial borehole fracturing for enhanced oil recovery and CO_(2)underground storage,a solution to the limited vertical stimulation reservoir volume in horizontal well fracturing.A numerical model is established to investigate the production rate,reservoir pressure field,and CO_(2)saturation distribution corresponding to changing time of CO_(2)flooding with radial borehole fracturing.A sensitivity analysis on the influence of CO_(2)injection location,layer spacing,pressure difference,borehole number,and hydraulic fractures on oil production and CO_(2)storage is conducted.The CO_(2)flooding process is divided into four stages.Reductions in layer spacing will significantly improve oil production rate and gas storage capacity.However,serious gas channeling can occur when the spacing is lower than 20 m.Increasing the pressure difference between the producer and injector,the borehole number,the hydraulic fracture height,and the fracture width can also increase the oil production rate and gas storage rate.Sensitivity analysis shows that layer spacing and fracture height greatly influence gas storage and oil production.Research outcomes are expected to provide a theoretical basis for the efficient development of shale oil reservoirs in the vertical direction.展开更多
The knots frequently occur in biopolymer and their diffusion plays an active role in the gene regulation.In this work,Langevin dynamics simulations were carried out to detect the diffusion behaviours of a knot along a...The knots frequently occur in biopolymer and their diffusion plays an active role in the gene regulation.In this work,Langevin dynamics simulations were carried out to detect the diffusion behaviours of a knot along a tensioned polymer in different spatial constraints.The polymer accommodating a knot was tethered to two macrospheres to block the unravelling of the knot.As a result,the curves for the diffusion coefficients of the knot with different bending stiffness as a function of the tension in different spatial constraints were obtained.In the space without constraints or with weak constraints,the corresponding curves for the knot with relatively large bending stiffness exhibited two turnover behaviours.On the contrary,for the knot with relatively small bending stiffness,the diffusion coefficients were monotonically reduced with increasing tension.However,in a space with strong constraints,all the curves showed one turnover behaviour regardless of the bending stiffness.The turnover behaviours divided the curves into different regimes,and the dominant diffusion mechanisms in the regimes,namely,knot-region breathing,self-reptation,and internal friction,were clearly identified.The effective friction coefficientsξof the knots with 3_(1),4_(1),5_(1) and 5_(2) types as a function of the knot size N at a fixed tension were well fitted by the relationξ∝N.The effective friction coefficients of the knots at relatively large tension f>3 sharply increased with the knot complexity,which is not dependent on the spatial constraints.By contrast,the values of these coefficients at relatively small tension f≤3 were remarkably dependent on the spatial constraints.Our work not only provides valuable simulation results to assist the understanding of the diffusion of DNA knot,but also highlights the single-molecule design for the manipulation of DNA knots in future.展开更多
文摘In the mid-21st century,natural gas will enter its golden age,and the era of natural gas is arriving.This paper reviews the development stages of global natural gas industry and the enlightenment of American shale gas revolution,summarizes the development history and achievements of the natural gas industry in China,analyzes the status and challenges of natural gas in the green and low-carbon energy transition,and puts forward the natural gas industry development strategies under carbon neutral target in China.The natural gas industry in China has experienced three periods:start,growth,and leap forward.At present,China has become the fourth largest natural gas producer and third largest natural gas consumer in the world,and has made great achievements in natural gas exploration and development theory and technology,providing important support for the growth of production and reserves.China has set its goal of carbon neutrality to promote green and sustainable development,which brings opportunities and challenges for natural gas industry.Natural gas has significant low-carbon advantages,and gas-electric peak shaving boosts new energy development;the difficulty and cost of development are more prominent.For the national energy security and harmonious development between economy and ecology under the carbon neutral goal,based on the principle of"comprehensive planning,technological innovation,multi-energy complementarity,diversified integration,flexibility and efficiency,optimization and upgrading",the construction of the production-supplystorage-marketing system has to be improved so as to boost the development of the natural gas industry.First,it is necessary to strengthen efforts in the exploration and development of natural gas,making projects and arrangement in key exploration and development areas,meanwhile,it is urgent to make breakthroughs in key science theories and technologies,so as to increase reserve and production.Second,it should promote green and innovative development of the natural gas by developing new techniques,expanding new fields and integrating with new energy.Third,there is a demand to realize transformation and upgrading of the supply and demand structure of natural gas by strengthening the layout of pipeline gas,liquefied natural gas and the construction of underground gas storage,establishing reserve system for improving abilities of emergency response and adjustment,raising the proportion of natural gas in the primary energy consumption and contributing to the transformation of energy consumption structure,realizing low-carbon resources utilization and clean energy consumption.
基金Youth Fund Project for Humanities and Social Sciences Research of the Ministry of Education,"Research on Designing Incentive Mechanisms and Policies for Large-Scale and Environmentally Friendly Offshore Oil and Gas Exploitation"(Project Number:19YJCZH106).
文摘The oceans'vast expanse has given rise to copious oil and gas resources,with recent years witnessing a steady unlocking of offshore oil and gas potential,positioning them as a key successor in global energy reserves.Currently,offshore oil and gas extraction constitutes nearly a third of the world's oil and gas output.This segment has evolved into a mutually beneficial ecosystem where operators and service providers collaborate closely around exploration and development activities.Investment in offshore oil and gas typically follows a dual "one-third’"pattern,reflecting high upfront costs but promising returns.It also underscores the stark variations in project viability and regional economic efficiency,with monopolistic traits seen at both national and corporate levels.Collaboration has emerged as a key tactic for resource-rich countries and oil companies to advance their offshore ventures.Given the distinct nature of offshore oil and gas development,Chinese oil companies are advised to seize opportunities in marine exploration,emphasize the coordination and planning abilities of the global supply chain,focus on the reserves of offshore oil and gas development technologies,as well as the capabilities of commercial talents and other forms of support,courageously pursue significant offshore assets,and effectively utilize global technology,equipment,and expertise,and rapidly build a competitive edge in offshore oil and gas projects.
基金funded by the South Oil Exploration and Development Company of PetroChina(2021-HNYJ-010).
文摘The Fushan Depression is one of the petroliferous depressions in the Beibuwan Basin,South China Sea.Previous studies have preliminarily explored the origin and source of crude oils in some areas of this depression.Nevertheless,no systematic investigations on the classification and origin of oils and hy-drocarbon migration processes have been made for the entire petroleum system in this depression,which has significantly hindered the hydrocarbon exploration in the region.A total of 32 mudstone and 58 oil samples from the Fushan Depression were analyzed to definite the detailed oil-source correlation within the sequence and sedimentary framework.The organic matter of third member of Paleogene Liushagang Formation(Els(3))source rocks,both deltaic and lacustrine mudstone,are algal-dominated with high abundance of C_(23)tricyclic terpane and C_(30)4-methylsteranes.The deltaic source rocks occur-ring in the first member(Els_(1))and second member(Els_(2))of the Paleogene Liushagang Formation are characterized by high abundance of C_(19+20)tricyclic terpane and oleanane,reflecting a more terrestrial plants contribution.While lacustrine source rocks of Els_(1)and Els_(2)display the reduced input of terrige-nous organic matter with relatively low abundance of C 19+20 tricyclic terpane and oleanane.Three types of oils were identified by their biomarker compositions in this study.Most of the oils discovered in the Huachang and Bailian Els_(1)reservoir belong to group A and were derived from lacustrine source rocks of Els_(1)and Els_(2).Group B oils are found within the Els_(1)and Els_(2)reservoirs,showing a close relation to the deltaic source rocks of Els_(1)and Els_(2),respectively.Group C oils,occurring in the Els3 reservoirs,have a good affinity with the Els3 source rocks.The spatial distribution and accumulation of different groups of oils are mainly controlled by the sedimentary facies and specific structural conditions.The Els_(2)reservoir in the Yong'an area belonging to Group B oil,are adjacent to the source kitchen and could be considered as the favorable exploration area in the future.
基金Supported by the PetroChina Science and Technology Major Project(2021ZZ01-05)Hainan Merit-based Recruitment Project(ZDYF2024SHFZ147)National Natural Science Foundation of China(NNSC)Project(52474033)。
文摘By systematically reviewing the development status of global carbon dioxide capture,utilization and storage(CCUS)cluster,and comparing domestic and international CCUS industrial models and successful experiences,this study explores the challenges and strategies for the scaled development of the CCUS industry of China.Globally,the CCUS industry has entered a phase of scaled and clustered development.North America has established a system of key technologies in large-scale CO_(2) capture,long-distance pipeline transmission,pipeline network optimization,and large-scale CO_(2) flooding for enhanced oil recovery(CO_(2)-EOR),with relatively mature cluster development and a gradual shift in industrial model from CO_(2)-EOR to geological storage.The CCUS industry of China has developed rapidly across all segments but remains in the early stage of cluster development,facing challenges such as absent business model,insufficient policy support,and technological gaps in core areas.China needs to improve the policy support system to boost enterprises participation across the entire industrial chain,strengthen top-level design and medium-to long-term planning to accelerate demonstration projects construction for whole-process CCUS clusters,advance for a full-chain technological system,including low-cost capture,pipeline optimization and EOR/storage integration technologies,and strengthen personnel training,strengthen discipline construction and university-enterprise research cooperation.
基金The National Natural Science Foundation of China under Grant Nos.11864006,11874309,12164007,and 12204118。
文摘In this work,Langevin dynamics simulations were carried out to thoroughly investigate the swapping process of composite knots under tension in a cuboid nanochannel.From our analysis,the free energy profiles of knot swapping under different conditions were extracted from the overall probability distribution of the relative distance between the centers of composite knots.In addition,the impact of the stretching force,confinement size,and bending stiffness on the free energy profiles was directly identified.Especially,the influence of topology structure is for the first time reported.The increasing stretching force in a fixed confinement or the confinement size under a constant stretching force does not alter their respective equilibrium populations at the separate state and the entangled state.In contrast,a bending stiffness larger than 15 enhanced the formation of the entangled state.The topology structure of the 51knot,which was different from the 52knot,resulted in forming a metastable state in the free energy profiles.The increasing stretching forces yielded an enhancement of the following free energy barrier.
基金the funding support from the National Natural Science Foundation of China(Grant Nos.52079091,42141010,and 42377147).
文摘Deep rock is under a complex geological environment with high geo-stress, high pore pressure, and strong dynamic disturbance. Understanding the dynamic response of rocks under coupled hydraulic-mechanical loading is thus essential in evaluating the stability and safety of subterranean engineering structures. Nevertheless, the constraints in experimental techniques have led to limited prior investigations into the dynamic compression behavior of rocks subjected to simultaneous high in-situ stress and pore pressure conditions. This study utilizes a triaxial split Hopkinson pressure bar (SHPB) system in conjunction with a pore pressure loading cell to conduct dynamic experiments on rocks subjected to hydraulic-mechanical loading. A porous green sandstone (GS) was adopted as the testing rock material. The findings reveal that the dynamic behavior of rock specimens is significantly influenced by multiple factors, including the loading rate, confining stress, and pore pressure. Specifically, the dynamic compressive strength of GS exhibits an increase with higher loading rates and greater confining pressures, while it decreases with elevated pore pressure. Moreover, the classical Ashby-Sammis micromechanical model was augmented to account for dynamic loading and pore pressure considerations. By deducing the connection between crack length and damage evolution, the resulting law of crack expansion rate is related to the strain rate. In addition, the influence of hydraulic factors on the stress intensity factor at the crack tip is introduced. Thereby, a dynamic constitutive model for deep rocks under coupled hydraulic-mechanical loading was established and then validated against the experimental results. Subsequently, the characteristics of introduced parameter for quantifying the water-induced effects were carefully discussed.
基金Supported by the CNPC Science and Technology Project(2024ZZ0203)。
文摘The ultra-deep(deeper than 8000 m)petroleum in the platform-basin zones of the Tarim Basin has been found mainly in the Lower Paleozoic reservoirs located to the east of the strike-slip fault F5 in the north depression.However,the source and exploration potential of the ultra-deep petroleum in the Cambrian on the west of F5 are still unclear.Through the analysis of lithofacies and biomarkers,it is revealed that there are at least three kinds of isochronous source rocks(SRs)in the Cambrian Newfoundland Series in Tarim Basin,which were deposited in three sedimentary environments,i.e.sulfide slope,deep-water shelf and restricted bay.In 2024,Well XT-1 in the western part of northern Tarim Basin has yielded a high production of condensate from the Cambrian.In the produced oil,entire aryl-isoprenoid alkane biomarkers were detected,but triaromatic dinosterane was absent.This finding is well consistent with the geochemical characteristics of the Newfoundland sulfidized slope SRs represented by those in wells LT-1 and QT-1,suggesting that the Newfoundland SRs are the main source of the Cambrian petroleum discovered in Well XT-1.Cambrian crude oil of Well XT-1 also presents the predominance of C29 steranes and is rich in long-chain tricyclic terpanes(up to C39),which can be the indicators for effectively distinguishing lithofacies such as siliceous mudstone and carbonate rock.Combined with the analysis of hydrocarbon accumulation in respect of conduction systems including thrust fault and strike-slip fault,it is found that the area to the west of F5 is possible to receive effective supply of hydrocarbons from the Cambrian Newfoundland SRs in Manxi hydrocarbon-generation center.This finding suggests that the area to the west of F5 will be a new target of exploration in the Cambrian ultra-deep structural-lithologic reservoirs in the Tarim Basin,in addition to the Cambrian ultra-deep platform-margin facies-controlled reservoirs in the eastern part of the basin.
文摘Human interaction with natural environments is gaining increasing attention in environmental sciences as research consistently shows that access to green spaces,clean air,and biodiversity plays a crucial role in enhancing physical health,reducing stress,and improving overall well-being.This study conducts a bibliometric and visualization-based analysis of forest therapy research,emphasizing its physiological and psychological benefits.Using the Web of Science database,we identified and analyzed 414 studies from 1998 to 2023.Through CiteSpace and VOSviewer,we mapped these documents to examine research trends,publication networks,leading scholars and institutions,key journals,and thematic evolution.Findings indicate that forest therapy research is predominantly concentrated in East Asia,North America,Australia,and Europe,with strong collaborative networks among authors and institutions.The concentration of publications,research evolution,and keyword trends reflect the development of forest therapy research.The analysis further identifies sixteen research clusters and discusses two research themes:physiological and psychological effects.By analyzing how the natural environment contributes to human well-being,we provide a comprehensive and visually structured understanding of forest therapy as an intersection of environmental science,public health and well-being,and ecosystem conservation.Our findings offer a new perspective for future interdisciplinary research,emphasizing the need for well-designed clinical trials to substantiate forest therapy’s diverse health effects and its role in promoting sustainable interactions between human societies and natural environments.
基金Supported by the China National Science and Technology Major Project(2025ZD1403000)CNPC Major Science and Technology Project(2023ZZ19).
文摘By integrating core observations,logging data and seismic interpretation,this study takes the massive Cretaceous carbonates in the M block of the Santos Basin,Brazil,as an example to establish the sequence filling pattern of fault-bounded isolated platforms in rift lake basins,reveal the control mechanisms of shoal-body development and reservoir formation,and reconstruct the evolutionary history of lithofacies paleogeography.The following results are obtained.(1)Three tertiary sequences(SQ1-SQ3)are identified in the Lower Cretaceous Itapema-Barra Velha of the M block.During the depositional period of SQ1,the rift basement faults controlled the stratigraphic distribution pattern of thick on both sides and thin in the middle.The strata overlapped to uplift in the early stage.During the depositional period of SQ2-SQ3,the synsedimentary faults controlled the paleogeomorphic reworking process with subsidence in the northwest and uplifting in the northeast,accompanied with the relative fall of lake level.(2)The Lower Cretaceous in the M block was deposited in a littoral-shallow lake,with the lithofacies paleogeographic pattern transiting from the inner clastic shoals and outer shelly shoals in SQ1 to the alternation of mounds and shoals in SQ2-SQ3.(3)Under the joint control of relative lake-level fluctuation,synsedimentary faults and volcanic activity,the shelly shoals in SQ1 tend to accumulated vertically in the raised area,and the mound-shoal complex in SQ2-SQ3 tends to migrate laterally towards the slope-break belt due to the reduction of accommodation space.(4)The evolution pattern of high-energy mounds and shoals,which were vertically accumulated in the early stage and laterally migrated in the later stage,controlled the transformation of high-quality reservoirs from“centralized”to“ring shaped”distribution.The research findings clarify the sedimentary patterns of mounds and shoals and the distribution of favorable reservoirs in the fault-controlled lacustrine isolated platform,providing support for the deepwater hydrocarbon exploration in the subsalt carbonate rocks in the Santos Basin.
文摘Field development practices in many shale gas regions(e.g.,the Changning region)have revealed a persistent issue of suboptimal reserve utilization,particularly in areas where the effective drainage width of production wells is less than half the inter-well spacing(typically 400-500 m).To address this,infill drilling has become a widely adopted and effective strategy for enhancing reservoir contact andmobilizing previously untapped reserves.However,this approach has introduced significant inter-well interference,complicating production dynamics and performance evaluation.The two primary challenges hindering efficient deployment of infill wells are:(1)the quantitative assessment of hydraulic and pressure connectivity between infill wells and their associated parent wells,and(2)the accurate estimation of platform-scale Estimated Ultimate Recovery(EUR)following infill implementation.This study presents a novel framework to quantify inter-well connectivity by deriving a material balance equation tailored for shale gas infill well groups,explicitly incorporating gas adsorption and desorption mechanisms.The model simultaneously evaluates formation pressure evolution and crossflow behavior between wells,offering a robust analytical basis for performance prediction.For infill wells intersecting the drainage boundaries of parent wells,EUR is estimated using an analytical model developed for multi-stage hydraulically fractured horizontal wells.Meanwhile,the EUR of the parent wells is obtained by summing their pre-infill EUR with the final inter-well crossflow contribution.
基金supported by the National Natural Science Foundation of China(42202175).
文摘Mineral identification is foundational to geological survey research,mineral resource exploration,and mining engineering.Considering the diversity of mineral types and the challenge of achieving high recognition accuracy for similar features,this study introduces a mineral detection method based on YOLOv8-SBI.This work enhances feature extraction by integrating spatial pyramid pooling-fast(SPPF)with the simplified self-attention module(SimAM),significantly improving the precision of mineral feature detection.In the feature fusion network,a weighted bidirectional feature pyramid network is employed for advanced cross-channel feature integration,effectively reducing feature redundancy.Additionally,Inner-Intersection Over Union(InnerIOU)is used as the loss function to improve the average quality localization performance of anchor boxes.Experimental results show that the YOLOv8-SBI model achieves an accuracy of 67.9%,a recall of 74.3%,a mAP@0.5 of 75.8%,and a mAP@0.5:0.95 of 56.7%,with a real-time detection speed of 244.2 frames per second.Compared to YOLOv8,YOLOv8-SBI demonstrates a significant improvement with 15.4%increase in accuracy,28.5%increase in recall,and increases of 28.1%and 20.9%in mAP@0.5 and mAP@0.5:0.95,respectively.Furthermore,relative to other models,such as YOLOv3,YOLOv5,YOLOv6,YOLOv8,YOLOv9,and YOLOv10,YOLOv8-SBI has a smaller parameter size of only 3.01×10^(6).This highlights the optimal balance between detection accuracy and speed,thereby offering robust technical support for intelligent mineral classification.
基金Supported by Key Science and Technology Project of Mudanjiang City(Z2017n0093)Fundamental Research Funds for Province-level Scientific Research Institutes of Heilongjiang Province(2018-01)
文摘Aornial mealnocarpa Elliot is a rare tree species that combined edible,medicinal,ornamental and ecological values. This article analyzes the economic value,domestic research and development status and development trend of A. mealnocarpa. Heilongjiang Province has been hurried to introduce A. mealnocarpa,lack of understanding of the characteristics of the tree species,resulting in serious cold damage and great economic losses. For these issues,proposals are put forward to promote the development of A. mealnocarpa planting industry.
文摘With the consideration of slip deformation mechanism and various slip systems of body centered cubic （BCC） metals, Taylor-type and finite element polycrystal models were embedded into the commercial finite element code ABAQUS to realize crystal plasticity finite element modeling, based on the rate dependent crystal constitutive equations. Initial orientations measured by electron backscatter diffraction （EBSD） were directly input into the crystal plasticity finite element model to simulate the develop- ment of rolling texture of interstitial-free steel （IF steel） at various reductions. The modeled results show a good agreement with the experimental results. With increasing reduction, the predicted and experimental rolling textures tend to sharper, and the results simulated by the Taylor-type model are stronger than those simulated by finite element model.＇Conclusions are obtained that rolling textures calculated with 48 { 110} 〈 111 〉＋ { 112 } 〈 111〉＋ { 123 } 〈 111 〉 slip systems are more approximate to EBSD results.
文摘With the booming development over the past years,geo-parks have achieved impressive progress together with a series of problems.Most importantly,geological tourism is not in prosperity.How to prosper geological tourism and achieve the sustainable development of geoparks is the top concern of workers engaged in tourism geology in China.This article discusses the problem from the perspective of core competitiveness of geo-parks,particularly from three aspects of subject,object and medium,and puts forward methods to form the core competitiveness.
基金financially supported by the National Natural Science Foundation(41274132)
文摘1 Introduction Now, the key of oil-field＇s increase production is the development technology for extra-low permeability reservoirs whose porosity is less than 5% and permeability less than 5 mD. The technologies of horizontal well, fracturing and gas driving are the advanced means of improving recovery.
基金supported by the National Natural Science Foundation of China(Grant No.52022087).
文摘The field data of shale fracturing demonstrate that the flowback performance of fracturing fluid is different from that of conventional reservoirs,where the flowback rate of shale fracturing fluid is lower than that of conventional reservoirs.At the early stage of flowback,there is no single-phase flow of the liquid phase in shale,but rather a gas-water two-phase flow,such that the single-phase flow model for tight oil and gas reservoirs is not applicable.In this study,pores and microfractures are extracted based on the experimental results of computed tomography(CT)scanning,and a spatial model of microfractures is established.Then,the influence of rough microfracture surfaces on the flow is corrected using the modified cubic law,which was modified by introducing the average deviation of the microfracture height as a roughness factor to consider the influence of microfracture surface roughness.The flow in the fracture network is simulated using the modified cubic law and the lattice Boltzmann method(LBM).The results obtained demonstrate that most of the fracturing fluid is retained in the shale microfractures,which explains the low fracturing fluid flowback rate in shale hydraulic fracturing.
基金supported by the National Natural Science Foundation of China(52104069,U20B6005)Beijing Municipal Natural Science Foundation(3232030)Science Foundation of China University of Petroleum,Beijing(2462023BJRC018,2462020YXZZ045).
文摘Natural gas hydrates,intricate crystalline structures formed by water molecules and small gas molecules,have emerged as a significant and globally impactful clean energy resource.However,their commercial exploitation faces challenges,particularly operational disruptions caused by sand-related blockages.Understanding the rheological properties of hydrate slurry,especially in the presence of micron-sized sand particles,is imperative for ensuring the flow assurance of subsea hydrate exploitation.This study extensively investigates the rheological properties of sand-containing hydrate slurries.The findings reveal that these slurries exhibit non-Newtonian fluid characteristics,including yield stress,thixotropy,and shear-thinning behavior.Solid-like elastic features are observed in sand-containing hydrate slurries before yielding,transitioning to viscous behavior after yielding.Even with a minimal amount of sand,both static yield stress and yield strain experience substantial changes,correlating with the increase in sand concentration.The research conclusively establishes the thixotropic nature of sand-hydrate slurries,where the viscosity decay rate is directly influenced by the shear rate.These insights aim to contribute comprehensively to the development of effective flow assurance strategies,ensuring the safe and stable operation of subsea hydrate exploitation.
基金supported by the National Natural Science Foundation of China(Nos.52125402 and 52174084)the Natural Science Foundation of Sichuan Province of China(No.2022NSFSC0005).
文摘The deep earth,deep sea,and deep space are the main parts of the national“three deep”strategy,which is in the forefront of the strategic deployment clearly defined in China’s 14th Five-Year Plan(2021-2025)and the Long-Range Objectives Through the Year 2035.It is important to reveal the evolutionary process and mechanism of deep tectonics to understand the earth’s past,present and future.The academic con-notation of Geology in Time has been given for the first time,which refers to the multi-field evolution response process of geological bodies at different time and spatial scales caused by geological processes inside and outside the Earth.Based on the deep in situ detection space and the unique geological envi-ronment of China Jinping Underground Laboratory,the scientific issue of the correlation mechanism and law between deep internal time-varying and shallow geological response is given attention.Innovative research and frontier exploration on deep underground in situ geo-information detection experiments for Geology in Time are designed to be carried out,which will have the potential to explore the driving force of Geology in Time,reveal essential laws of deep earth science,and explore innovative technologies in deep underground engineering.
基金This study has been funded by the National Science Fund for Distinguished Young Scholars(No.52204063)Science Foundation of China University of Petroleum,Beijing(No.2462023BJRC025).Moreover,we would like to express our heartfelt appreciation to the Computational Geosciences group in the Department of Mathematics and Cybernetics at SINTEF Digital for developing and providing the free open-source MATLAB Reservoir Simulation Toolbox(MRST)used in this research.
文摘This study introduces a novel method integrating CO_(2)flooding with radial borehole fracturing for enhanced oil recovery and CO_(2)underground storage,a solution to the limited vertical stimulation reservoir volume in horizontal well fracturing.A numerical model is established to investigate the production rate,reservoir pressure field,and CO_(2)saturation distribution corresponding to changing time of CO_(2)flooding with radial borehole fracturing.A sensitivity analysis on the influence of CO_(2)injection location,layer spacing,pressure difference,borehole number,and hydraulic fractures on oil production and CO_(2)storage is conducted.The CO_(2)flooding process is divided into four stages.Reductions in layer spacing will significantly improve oil production rate and gas storage capacity.However,serious gas channeling can occur when the spacing is lower than 20 m.Increasing the pressure difference between the producer and injector,the borehole number,the hydraulic fracture height,and the fracture width can also increase the oil production rate and gas storage rate.Sensitivity analysis shows that layer spacing and fracture height greatly influence gas storage and oil production.Research outcomes are expected to provide a theoretical basis for the efficient development of shale oil reservoirs in the vertical direction.
基金The National Natural Science Foundation of China under Grant Nos.11864006, 11874309, 12164007, and 12204118
文摘The knots frequently occur in biopolymer and their diffusion plays an active role in the gene regulation.In this work,Langevin dynamics simulations were carried out to detect the diffusion behaviours of a knot along a tensioned polymer in different spatial constraints.The polymer accommodating a knot was tethered to two macrospheres to block the unravelling of the knot.As a result,the curves for the diffusion coefficients of the knot with different bending stiffness as a function of the tension in different spatial constraints were obtained.In the space without constraints or with weak constraints,the corresponding curves for the knot with relatively large bending stiffness exhibited two turnover behaviours.On the contrary,for the knot with relatively small bending stiffness,the diffusion coefficients were monotonically reduced with increasing tension.However,in a space with strong constraints,all the curves showed one turnover behaviour regardless of the bending stiffness.The turnover behaviours divided the curves into different regimes,and the dominant diffusion mechanisms in the regimes,namely,knot-region breathing,self-reptation,and internal friction,were clearly identified.The effective friction coefficientsξof the knots with 3_(1),4_(1),5_(1) and 5_(2) types as a function of the knot size N at a fixed tension were well fitted by the relationξ∝N.The effective friction coefficients of the knots at relatively large tension f>3 sharply increased with the knot complexity,which is not dependent on the spatial constraints.By contrast,the values of these coefficients at relatively small tension f≤3 were remarkably dependent on the spatial constraints.Our work not only provides valuable simulation results to assist the understanding of the diffusion of DNA knot,but also highlights the single-molecule design for the manipulation of DNA knots in future.
