Background Stem cell transplantation has been shown to have beneficial effects on dilated cardiomyopathy. However, mechanism for stem cell homing to cardiac tissue in dilated cardiomyopathy has not yet been elucidated...Background Stem cell transplantation has been shown to have beneficial effects on dilated cardiomyopathy. However, mechanism for stem cell homing to cardiac tissue in dilated cardiomyopathy has not yet been elucidated. Methods Mesenchymal stem cells were obtained from rat bone marrow, expanded in vitro, and labeled with 99mmc. Cardiomyopathy model was induced by doxorubicin in rats. 9ernTC labeled cells were infused into the left ventricles in cardiomyopathy and control rats. Sixteen hours after injection, animals were sacrificed and different tissues were harvested to measure specific radioactivity. By use of real-time polymerase chain reaction and immunohistochemistry, mRNA and protein expressions for stromal-cell-derived factor 1 in cardiac tissue were measured. Results Labeling efficiency of mesenchymal stem cells was （70.0±11.2）%. Sixteen hours after mesenchymal stem cell transplantation, the heart-to-muscle radioactivity ratio was increased significantly in cardiomyopathy hearts as compared to control hearts. Both mRNA and protein expressions of cardiomyopathy hearts as compared with control hearts. Conclusion In dilated cardiomyopathy induced by doxorubicin in heart may induce mesenchymal stem cells home to the heart. stromal-cell-derived factor 1 were up-regulated in up-regulated expression of stromal-cell-derived factor I展开更多
Ⅰ. INTRODUCTIONSince 1966 a number of successful experiments have been made on the study of Mssbauer effect of M-type hexagonal ferrites, such as BaFe12O19 and SrFe12O19. As for the study results of Mssbauer effect o...Ⅰ. INTRODUCTIONSince 1966 a number of successful experiments have been made on the study of Mssbauer effect of M-type hexagonal ferrites, such as BaFe12O19 and SrFe12O19. As for the study results of Mssbauer effect of PbFe12O19 very little has been reported. Unlike BaFe12O19 and SrFe12O19, PbFe12O19 is not a technically important hardmagnetic material, but it is no less interesting to inquire microscopically into the different magnetic properties of them.展开更多
In this paper, the author classifies the finite inner π′-closed groups, and proves the following results1. If each proper subgroup K of a group G is weak π-homogeneous and weak π′-homogeneous, then G is a Schmidt...In this paper, the author classifies the finite inner π′-closed groups, and proves the following results1. If each proper subgroup K of a group G is weak π-homogeneous and weak π′-homogeneous, then G is a Schmidt group, or a direct product of two Hall subgroups.2. If G is a weak π-homogeneous group, then G is π′-closed if one of the following statements is true: (1)Each π-subgroup of G is 2-closed. (2) Each π-subgroup of G is 2′-closed.3. Let G be a group and π be a set of odd primes. If N_G(Z(J(P))) has a normal π-completement for a Sytow p-subgroup of G with prime ρ in π then so does G.展开更多
基金Acknowledgements： This work is supported by the Natural Science Foundation of Henan （No.0211021600, No.0324220079） and the Fundamental Researches of Henan （No.004061800）
基金This study was supported by the National Natural Science Foundation of China （No. 30900603）, Specialized Research Fund for the Doctoral Program of Higher Education （No. 20093234110008 and No. 20093234120008）, and Project Supported by Department of Health of Jiangsu Province （No. ZX07 200902）
文摘Background Stem cell transplantation has been shown to have beneficial effects on dilated cardiomyopathy. However, mechanism for stem cell homing to cardiac tissue in dilated cardiomyopathy has not yet been elucidated. Methods Mesenchymal stem cells were obtained from rat bone marrow, expanded in vitro, and labeled with 99mmc. Cardiomyopathy model was induced by doxorubicin in rats. 9ernTC labeled cells were infused into the left ventricles in cardiomyopathy and control rats. Sixteen hours after injection, animals were sacrificed and different tissues were harvested to measure specific radioactivity. By use of real-time polymerase chain reaction and immunohistochemistry, mRNA and protein expressions for stromal-cell-derived factor 1 in cardiac tissue were measured. Results Labeling efficiency of mesenchymal stem cells was （70.0±11.2）%. Sixteen hours after mesenchymal stem cell transplantation, the heart-to-muscle radioactivity ratio was increased significantly in cardiomyopathy hearts as compared to control hearts. Both mRNA and protein expressions of cardiomyopathy hearts as compared with control hearts. Conclusion In dilated cardiomyopathy induced by doxorubicin in heart may induce mesenchymal stem cells home to the heart. stromal-cell-derived factor 1 were up-regulated in up-regulated expression of stromal-cell-derived factor I
文摘Ⅰ. INTRODUCTIONSince 1966 a number of successful experiments have been made on the study of Mssbauer effect of M-type hexagonal ferrites, such as BaFe12O19 and SrFe12O19. As for the study results of Mssbauer effect of PbFe12O19 very little has been reported. Unlike BaFe12O19 and SrFe12O19, PbFe12O19 is not a technically important hardmagnetic material, but it is no less interesting to inquire microscopically into the different magnetic properties of them.
文摘In this paper, the author classifies the finite inner π′-closed groups, and proves the following results1. If each proper subgroup K of a group G is weak π-homogeneous and weak π′-homogeneous, then G is a Schmidt group, or a direct product of two Hall subgroups.2. If G is a weak π-homogeneous group, then G is π′-closed if one of the following statements is true: (1)Each π-subgroup of G is 2-closed. (2) Each π-subgroup of G is 2′-closed.3. Let G be a group and π be a set of odd primes. If N_G(Z(J(P))) has a normal π-completement for a Sytow p-subgroup of G with prime ρ in π then so does G.
