Objective: To describe the profiles and changing tendency of infant mortality born to teenage mother in the state of Nevada, 1980-2000, and explore the risk factors of infant mortality. Methods: The Nevada Linked Birt...Objective: To describe the profiles and changing tendency of infant mortality born to teenage mother in the state of Nevada, 1980-2000, and explore the risk factors of infant mortality. Methods: The Nevada Linked Birth/Infant Death data sets in 1980-2000 was analyzed. Total of 421964 live births were registered, which included 55419 live births born to teenage mother aged 10-20 years old. Multivariate binary logistic regression model was used to explore the risk factors of infant mortality and estimate the strength of association. Results: Infant mortality rate (IMR) born to teenage mother varied from 5.69 to 14.72 per 1000 live births in 1980-2000, mean IMR was 9.51 per 1000 live births during these 21 years, which were higher than IMRs born to 20 years or older mothers every year. IMRs in two groups seem to have an overall decline by year during this period. The infant mortality rate born to black teenage mother reached to 16.07 per 1000 live births, which was the highest one and significantly higher than those born to white, native American, Asian and other race mothers. Infant mortality rate generally appeared to decline by the increase of mothers age and 16 years old should be an important cut point. This study showed that Congenital anomalies: Club foot, Abnormal conditions of newborn: Meconium aspiration syndrome, Congenital anomaly: Heart malformation, Method of delivery: Repeat Csection, Abnormal conditions of newborn: Assisted ventilation <30min, Birth weight group, Tobacco use, The time mother prenatal care began were significantly positively associated with infant mortality born to teenage mothers, their odds ratios were 24.25, 10.68, 10.23, 4.73, 2.49, 2.00, 1.99 and 1.19 respectively. The clinical gestation estimates was significantly negatively associated with infant mortality as odds ratio of 0.79. Conclusion: Infant mortality born to teenage mother is one of important public problem in Nevada, there are different risk factors related to infant death born to teenage and adult mother. Teenage pregnancy and its outcome should be paid more attention to study.展开更多
The effects of high erucic acid rapeseed oil (HER) on fatty acid oxidation in rat liver compared with low erucic acid rapeseed oil (LER) were studied. Weanling male SD rats were fed diets containing 20% HER or LER for...The effects of high erucic acid rapeseed oil (HER) on fatty acid oxidation in rat liver compared with low erucic acid rapeseed oil (LER) were studied. Weanling male SD rats were fed diets containing 20% HER or LER for 1 week or 4 weeks, or 5% HER diet for 4 weeks. The hepatic oxidation capacity of butyric acid or palmitic acid was determined by titrating the propanone produced by their oxidation. The results showed that feeding HER to rats led to an increase in the weight of liver and a decrease in the hepatic oxidation capacity of palmitic acid. Hepatic oxidation of butyric acid was not influenced by the intake of HER. The inhibitory action of HER on the oxidation of long-chain fatty acids probably resulted from the incorporation of erucic acid into mitochondrial membranes, interfering the fatty acyl-CoA transfering system on the membranes, but not from the β-oxidation enzyme system in mitochondria being directly inhibited.展开更多
文摘Objective: To describe the profiles and changing tendency of infant mortality born to teenage mother in the state of Nevada, 1980-2000, and explore the risk factors of infant mortality. Methods: The Nevada Linked Birth/Infant Death data sets in 1980-2000 was analyzed. Total of 421964 live births were registered, which included 55419 live births born to teenage mother aged 10-20 years old. Multivariate binary logistic regression model was used to explore the risk factors of infant mortality and estimate the strength of association. Results: Infant mortality rate (IMR) born to teenage mother varied from 5.69 to 14.72 per 1000 live births in 1980-2000, mean IMR was 9.51 per 1000 live births during these 21 years, which were higher than IMRs born to 20 years or older mothers every year. IMRs in two groups seem to have an overall decline by year during this period. The infant mortality rate born to black teenage mother reached to 16.07 per 1000 live births, which was the highest one and significantly higher than those born to white, native American, Asian and other race mothers. Infant mortality rate generally appeared to decline by the increase of mothers age and 16 years old should be an important cut point. This study showed that Congenital anomalies: Club foot, Abnormal conditions of newborn: Meconium aspiration syndrome, Congenital anomaly: Heart malformation, Method of delivery: Repeat Csection, Abnormal conditions of newborn: Assisted ventilation <30min, Birth weight group, Tobacco use, The time mother prenatal care began were significantly positively associated with infant mortality born to teenage mothers, their odds ratios were 24.25, 10.68, 10.23, 4.73, 2.49, 2.00, 1.99 and 1.19 respectively. The clinical gestation estimates was significantly negatively associated with infant mortality as odds ratio of 0.79. Conclusion: Infant mortality born to teenage mother is one of important public problem in Nevada, there are different risk factors related to infant death born to teenage and adult mother. Teenage pregnancy and its outcome should be paid more attention to study.
文摘The effects of high erucic acid rapeseed oil (HER) on fatty acid oxidation in rat liver compared with low erucic acid rapeseed oil (LER) were studied. Weanling male SD rats were fed diets containing 20% HER or LER for 1 week or 4 weeks, or 5% HER diet for 4 weeks. The hepatic oxidation capacity of butyric acid or palmitic acid was determined by titrating the propanone produced by their oxidation. The results showed that feeding HER to rats led to an increase in the weight of liver and a decrease in the hepatic oxidation capacity of palmitic acid. Hepatic oxidation of butyric acid was not influenced by the intake of HER. The inhibitory action of HER on the oxidation of long-chain fatty acids probably resulted from the incorporation of erucic acid into mitochondrial membranes, interfering the fatty acyl-CoA transfering system on the membranes, but not from the β-oxidation enzyme system in mitochondria being directly inhibited.