Because of an unfortunate mistake during the production of this article,the Acknowledgements have been omitted.The Acknowledgements are added as follows:Sasan YAZDANI would like to thank the Scientific and Technologic...Because of an unfortunate mistake during the production of this article,the Acknowledgements have been omitted.The Acknowledgements are added as follows:Sasan YAZDANI would like to thank the Scientific and Technological Research Council of Turkey(TÜB˙ITAK)for receiving financial support for this work through the 2221 Fellowship Program for Visiting Scientists and Scientists on Sabbatical Leave(Grant ID:E 21514107-115.02-228864).Sasan YAZDANI also expresses his gratitude to Sahand University of Technology for granting him sabbatical leave to facilitate the completion of this research.展开更多
This study reports the response of helium(He)ion irradiation on binary-phase structured alloy V_(34)Ti_(25)Cr_(10)Ni_(30)Pd1.The alloy consists of a VCr matrix with nano-sized TiNi precipitates and a B2 TiNi matrix wi...This study reports the response of helium(He)ion irradiation on binary-phase structured alloy V_(34)Ti_(25)Cr_(10)Ni_(30)Pd1.The alloy consists of a VCr matrix with nano-sized TiNi precipitates and a B2 TiNi matrix with nano-sized VCr precipitates.VCr is chemical-disordered and TiNi has a B2-ordered structure.The alloy was subjected to 400 keV He ion irradiation with a fluence of 1×10^(17)ions cm^(−2)at 450℃.The results show He bubbles within the chemical-disordered VCr matrix exhibit a near-spherical shape with a smaller size and higher density compared to that in chemical-ordered TiNi phase with a larger size,lower density,and faceted shape.This indicates the chemical-disordered VCr phase effectively suppresses He accumulation compared to the B2-ordered TiNi phase,emphasizing the dominance of chemical struc-tures in He bubble formation.The calculation of density functional theory(DFT)shows that Ti and Ni have lower vacancy formation energy than that of V and Cr,respectively,which results in the increased vacancy production in TiNi.Consequently,He bubbles in TiNi have a larger bubble size consistent with experimental observations of radiation-induced Ni segregation.These findings elucidate the roles of or-dered and disordered chemical structures in He bubble evolution,offering insights for the development of gas ion irradiation-resistant materials.展开更多
A laser phase determination method and a transfer function that includes a proportional term of a measured photoelectron energy spectrum are presented to directly measure the detailed temporal structure of a narrow ba...A laser phase determination method and a transfer function that includes a proportional term of a measured photoelectron energy spectrum are presented to directly measure the detailed temporal structure of a narrow bandwidth attosecond extreme-ultraviolet （EUV） pulse. The method is based on the spectrum measurement of an electron generated by EUV photo-ionization interacting with a femtosecond laser field. The results of the study suggest that measurements should be taken at 0° or 180° with respect to the linear laser polarization. The method has a temporal measurement range of about half a laser oscillation period. The temporal resolution also depends on the jitter and control precision of the laser and EUV pulses.展开更多
6016-T4 aluminum alloy and DP490 steel were systematically tested under 24 proportional loading paths,including uniaxial tensile tests with a 15°increment,uniaxial compressive and simple shear tests with a 45...6016-T4 aluminum alloy and DP490 steel were systematically tested under 24 proportional loading paths,including uniaxial tensile tests with a 15°increment,uniaxial compressive and simple shear tests with a 45°increment,and biaxial tensile tests using cruciform specimens.Cruciform specimens in the rolling/transverse and 45°/135°sampling directions were tested with seven and four different stress ra-tios,respectively.The normal and diagonal planes plastic work contours and the yield stresses under uniaxial tension and compression were measured to investigate the anisotropic yield.Meanwhile,the normal and diagonal planes directions of plastic strain rate and the rα-values under uniaxial tension and compression were characterized to confirm the plastic flow.Several existing asymmetric yield crite-ria under the associated and non-associated flow rules were comprehensively evaluated to describe the asymmetric plastic anisotropy of 6016-T4 aluminum alloy and DP490 steel.The results suggest that in the investigated yield criteria,the non-associated models can predict the tension and compression asym-metry of materials more accurately than the associated models,and the function of stress triaxiality can more effectively describe the asymmetric yield behavior than the first stress invariant.In addition,the pure shear stress states are helpful in assessing the validity and applicability of advanced asymmetric yield stress functions,and the inspection of diagonal plane plastic work contours containing more pure shear stress states should prioritized over that of normal plane plastic work contours.The evaluation of plastic potential functions should not only consider the prediction accuracy of the normal plane di-rections of plastic strain rate,but also further check the diagonal plane directions of plastic strain rate.Expressing mechanical properties as a function of equivalent plastic strain to calibrate parameters of the yield criterion allows the continuous capture of anisotropic evolution of the asymmetric yield surface and the changes in the asymmetric plastic potential surface.展开更多
In the present study,split tensile strength of self-compacting concrete with different amount of CuO nanoparticles has been investigated.CuO nanoparticles with the average particle size of 15 nm were added partially t...In the present study,split tensile strength of self-compacting concrete with different amount of CuO nanoparticles has been investigated.CuO nanoparticles with the average particle size of 15 nm were added partially to self compacting concrete and split tensile strength of the specimens has been measured.The results indicate that CuO nanoparticles are able to improve the split tensile strength of self compacting concrete and recover the negative effects of polycarboxylate superplasticizer on split tensile strength.CuO nanoparticle as a partial replacement of cement up to 4 wt% could accelerate C-S-H gel formation as a result of increased crystalline Ca（OH）2 amount at the early ages of hydration.The increase of the CuO nanoparticles more than 4 wt% causes the decrease of the split tensile strength because of unsuitable dispersion of nanoparticles in the concrete matrix.Accelerated peak appearance in conduction calorimetry tests,more weight loss in thermogravimetric analysis and more rapid appearance of related peaks to hydrated products in X-ray diffraction（XRD） results all also indicate that CuO nanoparticles up to4 wt% could improve the mechanical and physical properties of the specimens.Finally,CuO nanoparticles could improve the pore structure of concrete and shift the distributed pores to harmless and few-harm pores.展开更多
For the first time,the analytical continuation in the coupling constant method has been combined with the relativistic mean field theory to study the unbound states in spherical nuclei.The 1d_(3/2) neutron state in ^(...For the first time,the analytical continuation in the coupling constant method has been combined with the relativistic mean field theory to study the unbound states in spherical nuclei.The 1d_(3/2) neutron state in ^(16)O and the 2d_(5/2) and 1g_(9/2) neutron states in ^(48)Ca are taken as examples.The calculated energies and widths are compared with available data.展开更多
Laser phase relations of high-order harmonic generation （HHG） are calculated with the saddle point theory. The results show a two-peak structure including a symmetric and an asymmetric temporal distributions of the ...Laser phase relations of high-order harmonic generation （HHG） are calculated with the saddle point theory. The results show a two-peak structure including a symmetric and an asymmetric temporal distributions of the instantaneous frequency of HHG radiation. These distributions are fitted with Gaussian and polynomial functions, respectively. Two calculation formulae are presented to analyse attosecond x-rays with specified time duration and energy bandwidth in experiments.展开更多
The application of numerical weather prediction （NWP） products is increasing dramatically. Existing reports indicate that ensemble predictions have better skill than deterministic forecasts. In this study, numerical...The application of numerical weather prediction （NWP） products is increasing dramatically. Existing reports indicate that ensemble predictions have better skill than deterministic forecasts. In this study, numerical ensemble precipitation forecasts in the TIGGE database were evaluated using deterministic, dichotomous （yes/no）, and probabilistic techniques over Iran for the period 2008-16. Thirteen rain gauges spread over eight homogeneous precipitation regimes were selected for evaluation. The Inverse Distance Weighting and Kriging methods were adopted for interpolation of the prediction values, downscaled to the stations at lead times of one to three days. To enhance the forecast quality, NWP values were post-processed via Bayesian Model Averaging. The results showed that ECMWF had better scores than other products. However, products of all centers underestimated precipitation in high precipitation regions while overestimating precipitation in other regions. This points to a systematic bias in forecasts and demands application of bias correction techniques. Based on dichotomous evaluation, NCEP did better at most stations, although all centers overpredicted the number of precipitation events. Compared to those of ECMWF and NCER UKMO yielded higher scores in mountainous regions, but performed poorly at other selected stations. Furthermore, the evaluations showed that all centers had better skill in wet than in dry seasons. The quality of post-processed predictions was better than those of the raw predictions. In conclusion, the accuracy of the NWP predictions made by the selected centers could be classified as medium over Iran, while post-processing of predictions is recommended to improve the quality.展开更多
In this study,the effect of different sampling rates(i.e.observation recording interval)on the Precise Point Positioning(PPP)solutions in terms of accuracy was investigated.For this purpose,a field test was carried ou...In this study,the effect of different sampling rates(i.e.observation recording interval)on the Precise Point Positioning(PPP)solutions in terms of accuracy was investigated.For this purpose,a field test was carried out inÇorum province,Turkey,on 11 September 2019.Within this context,a Geodetic Point(GP)was established and precisely coordinated.A static GNSS measurement was occupied on the GP for about 4-hour time at 0.10 second(s)/10 Hz measurement intervals with the Trimble R10 geodetic grade GNSS receiver.The original observation file was converted to RINEX format and then decimated into the different data sampling rates as 0.2 s,0.5 s,1 s,5 s,10 s,30 s,60 s,and 120 s.All these RINEX observation files were submitted to the Canadian Spatial Reference System-Precise Point Positioning(CSRS-PPP)online processing service the day after the data collection date by choosing both static and kinematic processing options.In this way,PPP-derived static coordinates,and the kinematic coordinates of each measurement epoch were calculated.The PPP-derived coordinates obtained from each decimated sampling intervals were compared to known coordinates of the GP for northing,easting,2D position,and height components.According to the static and kinematic processing results,high data sampling rates did not change the PPP solutions in terms of accuracy when compared to the results obtained using lower sampling rates.The results of this study imply that it was not necessary to collect GNSS data with high-rate intervals for many surveying projects requiring cm-level accuracy.展开更多
Osteoarthritis(OA)is a debilitating degenerative disease affecting multiple joint tissues,including cartilage,bone,synovium,and adipose tissues.OA presents diverse clinical phenotypes and distinct molecular endotypes,...Osteoarthritis(OA)is a debilitating degenerative disease affecting multiple joint tissues,including cartilage,bone,synovium,and adipose tissues.OA presents diverse clinical phenotypes and distinct molecular endotypes,including inflammatory,metabolic,mechanical,genetic,and synovial variants.Consequently,innovative technologies are needed to support the development of effective diagnostic and precision therapeutic approaches.Traditional analysis of bulk OA tissue extracts has limitations due to technical constraints,causing challenges in the differentiation between various physiological and pathological phenotypes in joint tissues.This issue has led to standardization difficulties and hindered the success of clinical trials.Gaining insights into the spatial variations of the cellular and molecular structures in OA tissues,encompassing DNA,RNA,metabolites,and proteins,as well as their chemical properties,elemental composition,and mechanical attributes,can contribute to a more comprehensive understanding of the disease subtypes.Spatially resolved biology enables biologists to investigate cells within the context of their tissue microenvironment,providing a more holistic view of cellular function.Recent advances in innovative spatial biology techniques now allow intact tissue sections to be examined using various-omics lenses,such as genomics,transcriptomics,proteomics,and metabolomics,with spatial data.This fusion of approaches provides researchers with critical insights into the molecular composition and functions of the cells and tissues at precise spatial coordinates.Furthermore,advanced imaging techniques,including high-resolution microscopy,hyperspectral imaging,and mass spectrometry imaging,enable the visualization and analysis of the spatial distribution of biomolecules,cells,and tissues.Linking these molecular imaging outputs to conventional tissue histology can facilitate a more comprehensive characterization of disease phenotypes.This review summarizes the recent advancements in the molecular imaging modalities and methodologies for in-depth spatial analysis.It explores their applications,challenges,and potential opportunities in the field of OA.Additionally,this review provides a perspective on the potential research directions for these contemporary approaches that can meet the requirements of clinical diagnoses and the establishment of therapeutic targets for OA.展开更多
The equations ofstate of the neutron star matter are calculated in the relativistic mean-field approximation witl different hyperon coupling constants. The properties of neutron stars are studied by solving the Oppenh...The equations ofstate of the neutron star matter are calculated in the relativistic mean-field approximation witl different hyperon coupling constants. The properties of neutron stars are studied by solving the OppenheimerVolkoff equation. It manifests the properties of neutron stars - change explicitly as different hyperon coupling constants are concerned.展开更多
In the present study, fracture toughness of functionally graded steels in crack divider configuration has been modeled. By utilizing plain carbon and austenitic stainless steels slices with various thicknesses and arr...In the present study, fracture toughness of functionally graded steels in crack divider configuration has been modeled. By utilizing plain carbon and austenitic stainless steels slices with various thicknesses and arrangements as electroslag remelting electrodes, functionally graded steels were produced. The fracture toughness of the functionally graded steels in crack divider configuration has been found to depend on the composites＇ type together with the volume fraction and the position of the containing phases. According to the area under stress-strain curve of each layer in the functionally graded steels, a mathematical model has been presented for predicting fracture toughness of composites by using the rule of mixtures. The fracture toughness of each layer has been modified according to the position of that layer where for the edge layers, net plane stress condition was supposed and for the central layers, net plane strain condition was presumed. There is a good agreement between experimental results and those acquired from the analytical model.展开更多
BACKGROUND Type 1 diabetes(T1D),a chronic metabolic and autoimmune disease,seriously endangers human health.In recent years,mesenchymal stem cell(MSC)transplantation has become an effective treatment for diabetes.Mens...BACKGROUND Type 1 diabetes(T1D),a chronic metabolic and autoimmune disease,seriously endangers human health.In recent years,mesenchymal stem cell(MSC)transplantation has become an effective treatment for diabetes.Menstrual bloodderived endometrial stem cells(MenSC),a novel MSC type derived from the decidual endometrium during menstruation,are expected to become promising seeding cells for diabetes treatment because of their noninvasive collection procedure,high proliferation rate and high immunomodulation capacity.AIM To comprehensively compare the effects of MenSC and umbilical cord-derived MSC(UcMSC)transplantation on T1D treatment,to further explore the potential mechanism of MSC-based therapies in T1D,and to provide support for the clinical application of MSC in diabetes treatment.METHODS A conventional streptozotocin-induced T1D mouse model was established,and the effects of MenSC and UcMSC transplantation on their blood glucose and serum insulin levels were detected.The morphological and functional changes in the pancreas,liver,kidney,and spleen were analyzed by routine histological and immunohistochemical examinations.Changes in the serum cytokine levels in the model mice were assessed by protein arrays.The expression of target proteins related to pancreatic regeneration and apoptosis was examined by western blot.RESULTS MenSC and UcMSC transplantation significantly improved the blood glucose and serum insulin levels in T1D model mice.Immunofluorescence analysis revealed that the numbers of insulin+and CD31+cells in the pancreas were significantly increased in MSC-treated mice compared with control mice.Subsequent western blot analysis also showed that vascular endothelial growth factor(VEGF),Bcl2,Bcl-xL and Proliferating cell nuclear antigen in pancreatic tissue was significantly upregulated in MSC-treated mice compared with control mice.Additionally,protein arrays indicated that MenSC and UcMSC transplantation significantly downregulated the serum levels of interferonγand tumor necrosis factorαand upregulated the serum levels of interleukin-6 and VEGF in the model mice.Additionally,histological and immunohistochemical analyses revealed that MSC transplantation systematically improved the morphologies and functions of the liver,kidney,and spleen in T1D model mice.CONCLUSION MenSC transplantation significantly improves the symptoms in T1D model mice and exerts protective effects on their main organs.Moreover,MSC-mediated angiogenesis,antiapoptotic effects and immunomodulation likely contribute to the above improvements.Thus,MenSC are expected to become promising seeding cells for clinical diabetes treatment due to their advantages mentioned above.展开更多
Time for single vehicle combat preparation(TSVCP) is an important characteristic parameter for the operational support feature of armored vehicle. During the development phase, how to validate the TSVCP of armored veh...Time for single vehicle combat preparation(TSVCP) is an important characteristic parameter for the operational support feature of armored vehicle. During the development phase, how to validate the TSVCP of armored vehicle through analytic method is a difficult issue in analysis and validation of vehicle supportability.This paper uses Monte Carlo approach and builds a working model for single vehicle combat preparation(SVCP)of armored vehicle, thus realizes the prediction and analysis of the TSVCP of armored vehicle, and finally validates the effectiveness of the approach by example.展开更多
Objective:The activity of enzymes participating in the systems of antioxidant protection was assayed in the peel and pulp of sunflower.The essential roles of proteases in food stimulate research to find other sources ...Objective:The activity of enzymes participating in the systems of antioxidant protection was assayed in the peel and pulp of sunflower.The essential roles of proteases in food stimulate research to find other sources of the enzyme especially from non-conventional sources.In the present work,we study several biochemical parameters in the pulp and peel of sunflower.Methods:Pulp and peel of sunflower was extracted,antioxidant enzymes and nonenzymatic antioxidant were measured.Alkaline protease was measured and purified from pulp in sunflower.Results:High carbohydrate concentration,beta-carotene,catalase and ascorbate peroxidase activities,free radical scavenging capacity and free flavonoid content were observed in the peel of sunflower.Whereas,MDA and ceruloplasmin activities were high in the pulp of sunflower.Conclusions:The present study concluded that peel in sunflower are strong radical scavengers and can be considered as good sources of natural antioxidants for medicinal and commercial uses.Further analysis showed that protease activity was a significantly high in the pulp compared to the peel.展开更多
Quantitative investigations are made for the laser-duration dependence of the emission properties of high-order harmonic generation （HHG）. HHG emission properties produced by few-cycle lasers show some useful charac...Quantitative investigations are made for the laser-duration dependence of the emission properties of high-order harmonic generation （HHG）. HHG emission properties produced by few-cycle lasers show some useful characteristics. The cutoff energy is less than that by laser for infinite duration. The single energy distribution pulse decreases much faster than its duration as the laser duration grows. A two-cycle laser with carrier-envelope phase of 0° can produce a single distribution pulse peaked at the laser carrier phase 1.22 rad and spanned 1.18 rad with the cutoff energy 2.9Up ＋ Ip and a bandwidth 0.63Up, where Up is the ponderomotive potential of the laser field and Ip is the atomic ionization potential.展开更多
For the disadvantages of analyzing system reliability using common Bayes method,an evaluation method based on improved Bayes-Bootstrap method is presented.Firstly,the data obliteration problem existing in traditional ...For the disadvantages of analyzing system reliability using common Bayes method,an evaluation method based on improved Bayes-Bootstrap method is presented.Firstly,the data obliteration problem existing in traditional Bayes method is analyzed,then an improved sampling arithmetic is proposed on the foundation of an experience function.Finally,effectiveness of this method is proved by an example.The simulating result shows that this method is more accurate than common Bayes method.展开更多
In this study,the microstructure and mechanical properties of a multi-layered 316L-TiC composite material produced by selective laser melting(SLM)additive manufacturing process are investigated.Three different layers,...In this study,the microstructure and mechanical properties of a multi-layered 316L-TiC composite material produced by selective laser melting(SLM)additive manufacturing process are investigated.Three different layers,consisting of 316L stainless steel,316L-5 wt%TiC and 316L-10 wt%TiC,were additively manufactured.The microstructure of these layers was characterized by optical microscopy(OM)and scanning electron microscopy(SEM).X-ray diffraction(XRD)was used for phase analysis,and the mechanical properties were evaluated by tensile and nanoindentation tests.The microstructural observations show epitaxial grain growth within the composite layers,with the elongated grains growing predominantly in the build direction.XRD analysis confirms the successful incorporation of the TiC particles into the 316L matrix,with no unwanted phases present.Nanoindentation results indicate a significant increase in the hardness and modulus of elasticity of the composite layers compared to pure 316L stainless steel,suggesting improved mechanical properties.Tensile tests show remarkable strength values for the 316L-TiC composite samples,which can be attributed to the embedded TiC particles.These results highlight the potential of SLM in the production of multi-layer metal-ceramic composites for applications that require high strength and ductility of metallic components in addition to the exceptional hardness of the ceramic particles.展开更多
This article focuses on the performance analysis of both real-time and post-mission kinematic precise point positioning(PPP)in challenging marine environments.For this purpose,a real dynamic experiment lasting 6 h was...This article focuses on the performance analysis of both real-time and post-mission kinematic precise point positioning(PPP)in challenging marine environments.For this purpose,a real dynamic experiment lasting 6 h was carried out on a lake dam in?orum City of Turkey.While the kinematic test was continuing,the real-time PPP coordinates were obtained for each measurement epoch with a commercial real-time PPP(RT-PPP)service,namely the Trimble Center Point RTX.Then the post-mission PPP(PM-PPP)coordinates were calculated by using Multi-GNSS data and the Multi-GNSS Experiment(MGEX)precise products.The kinematic RT-PPP and PM-PPP results showed that the PPP coordinates were consistent with the relative solution at centimetre and decimetre level in horizontal and height components,respectively.This study implies that PPP technique is a powerful tool for highly accurate positioning in both real-time and post-mission modes,even for dynamic applications in harsh environments.展开更多
The new numerical approach for analysis of the warhead transportations is suggested.This approach allows to control the warhead operability before its experimental analysis.The approach is implemented by the adequate ...The new numerical approach for analysis of the warhead transportations is suggested.This approach allows to control the warhead operability before its experimental analysis.The approach is implemented by the adequate models for the software ANSYS.Analysis of the loads at land operations and transportations of the warhead by natural roads,water and aviation allows to obtain the maximal values of loads,which are used in numerical simulations of the warhead.These loads give an opportunity to analyze the operability and the fatigue strength of the cartridge warhead.The numerical simulations of the attachments of the warhead combat elements are performed on the basis of the suggested method.The data of the numerical simulations verifies the operability of the fastener system of the warhead combat elements.展开更多
文摘Because of an unfortunate mistake during the production of this article,the Acknowledgements have been omitted.The Acknowledgements are added as follows:Sasan YAZDANI would like to thank the Scientific and Technological Research Council of Turkey(TÜB˙ITAK)for receiving financial support for this work through the 2221 Fellowship Program for Visiting Scientists and Scientists on Sabbatical Leave(Grant ID:E 21514107-115.02-228864).Sasan YAZDANI also expresses his gratitude to Sahand University of Technology for granting him sabbatical leave to facilitate the completion of this research.
基金supported by the National Magnetic Con-finement Fusion Energy Research Project from the Ministry of Science and Technology of China(No.2022YFE03030004 and 2019YFE03120003)the National Natural Science Foundation of China(No.12275010,12275176,12275001,12335017,11921006,U21B2082,U22B2064 and U20B2025)+3 种基金the Beijing Municipal Natural Science Foundation(No.1222023)the Shenzhen Science and Technology Program(No.RCYX20210609103904028)Engang Fu acknowledges the support from the Science Fund or Creative Research Groups of NSFC,the Ion Beam Materials Laboratory(IBML)and Electron Microscopy Laboratory(EML)the High-performance Computing Platform(HPC)at Peking University.Xing Liu acknowledges the discussion with Prof.Ning Gao and Dr.Yifan Zhang.
文摘This study reports the response of helium(He)ion irradiation on binary-phase structured alloy V_(34)Ti_(25)Cr_(10)Ni_(30)Pd1.The alloy consists of a VCr matrix with nano-sized TiNi precipitates and a B2 TiNi matrix with nano-sized VCr precipitates.VCr is chemical-disordered and TiNi has a B2-ordered structure.The alloy was subjected to 400 keV He ion irradiation with a fluence of 1×10^(17)ions cm^(−2)at 450℃.The results show He bubbles within the chemical-disordered VCr matrix exhibit a near-spherical shape with a smaller size and higher density compared to that in chemical-ordered TiNi phase with a larger size,lower density,and faceted shape.This indicates the chemical-disordered VCr phase effectively suppresses He accumulation compared to the B2-ordered TiNi phase,emphasizing the dominance of chemical struc-tures in He bubble formation.The calculation of density functional theory(DFT)shows that Ti and Ni have lower vacancy formation energy than that of V and Cr,respectively,which results in the increased vacancy production in TiNi.Consequently,He bubbles in TiNi have a larger bubble size consistent with experimental observations of radiation-induced Ni segregation.These findings elucidate the roles of or-dered and disordered chemical structures in He bubble evolution,offering insights for the development of gas ion irradiation-resistant materials.
文摘A laser phase determination method and a transfer function that includes a proportional term of a measured photoelectron energy spectrum are presented to directly measure the detailed temporal structure of a narrow bandwidth attosecond extreme-ultraviolet （EUV） pulse. The method is based on the spectrum measurement of an electron generated by EUV photo-ionization interacting with a femtosecond laser field. The results of the study suggest that measurements should be taken at 0° or 180° with respect to the linear laser polarization. The method has a temporal measurement range of about half a laser oscillation period. The temporal resolution also depends on the jitter and control precision of the laser and EUV pulses.
基金the Promotion China Ph.D.Pro-gram of BMW Brilliance Automotive Ltd.and Beijing Municipal Ed-ucation Commission and Beijing Municipal Natural Science Foun-dation(No.KZ200010009041)for financial support and KOBELCO and TAGAL for providing commercial automotive sheets.
文摘6016-T4 aluminum alloy and DP490 steel were systematically tested under 24 proportional loading paths,including uniaxial tensile tests with a 15°increment,uniaxial compressive and simple shear tests with a 45°increment,and biaxial tensile tests using cruciform specimens.Cruciform specimens in the rolling/transverse and 45°/135°sampling directions were tested with seven and four different stress ra-tios,respectively.The normal and diagonal planes plastic work contours and the yield stresses under uniaxial tension and compression were measured to investigate the anisotropic yield.Meanwhile,the normal and diagonal planes directions of plastic strain rate and the rα-values under uniaxial tension and compression were characterized to confirm the plastic flow.Several existing asymmetric yield crite-ria under the associated and non-associated flow rules were comprehensively evaluated to describe the asymmetric plastic anisotropy of 6016-T4 aluminum alloy and DP490 steel.The results suggest that in the investigated yield criteria,the non-associated models can predict the tension and compression asym-metry of materials more accurately than the associated models,and the function of stress triaxiality can more effectively describe the asymmetric yield behavior than the first stress invariant.In addition,the pure shear stress states are helpful in assessing the validity and applicability of advanced asymmetric yield stress functions,and the inspection of diagonal plane plastic work contours containing more pure shear stress states should prioritized over that of normal plane plastic work contours.The evaluation of plastic potential functions should not only consider the prediction accuracy of the normal plane di-rections of plastic strain rate,but also further check the diagonal plane directions of plastic strain rate.Expressing mechanical properties as a function of equivalent plastic strain to calibrate parameters of the yield criterion allows the continuous capture of anisotropic evolution of the asymmetric yield surface and the changes in the asymmetric plastic potential surface.
文摘In the present study,split tensile strength of self-compacting concrete with different amount of CuO nanoparticles has been investigated.CuO nanoparticles with the average particle size of 15 nm were added partially to self compacting concrete and split tensile strength of the specimens has been measured.The results indicate that CuO nanoparticles are able to improve the split tensile strength of self compacting concrete and recover the negative effects of polycarboxylate superplasticizer on split tensile strength.CuO nanoparticle as a partial replacement of cement up to 4 wt% could accelerate C-S-H gel formation as a result of increased crystalline Ca（OH）2 amount at the early ages of hydration.The increase of the CuO nanoparticles more than 4 wt% causes the decrease of the split tensile strength because of unsuitable dispersion of nanoparticles in the concrete matrix.Accelerated peak appearance in conduction calorimetry tests,more weight loss in thermogravimetric analysis and more rapid appearance of related peaks to hydrated products in X-ray diffraction（XRD） results all also indicate that CuO nanoparticles up to4 wt% could improve the mechanical and physical properties of the specimens.Finally,CuO nanoparticles could improve the pore structure of concrete and shift the distributed pores to harmless and few-harm pores.
基金Supported partly by the Major State Basic Research Development Program under Contract Number G2000077407the National Natural Science Foundation of China under Grant Nos.19847002 and 19935030.
文摘For the first time,the analytical continuation in the coupling constant method has been combined with the relativistic mean field theory to study the unbound states in spherical nuclei.The 1d_(3/2) neutron state in ^(16)O and the 2d_(5/2) and 1g_(9/2) neutron states in ^(48)Ca are taken as examples.The calculated energies and widths are compared with available data.
文摘Laser phase relations of high-order harmonic generation （HHG） are calculated with the saddle point theory. The results show a two-peak structure including a symmetric and an asymmetric temporal distributions of the instantaneous frequency of HHG radiation. These distributions are fitted with Gaussian and polynomial functions, respectively. Two calculation formulae are presented to analyse attosecond x-rays with specified time duration and energy bandwidth in experiments.
文摘The application of numerical weather prediction （NWP） products is increasing dramatically. Existing reports indicate that ensemble predictions have better skill than deterministic forecasts. In this study, numerical ensemble precipitation forecasts in the TIGGE database were evaluated using deterministic, dichotomous （yes/no）, and probabilistic techniques over Iran for the period 2008-16. Thirteen rain gauges spread over eight homogeneous precipitation regimes were selected for evaluation. The Inverse Distance Weighting and Kriging methods were adopted for interpolation of the prediction values, downscaled to the stations at lead times of one to three days. To enhance the forecast quality, NWP values were post-processed via Bayesian Model Averaging. The results showed that ECMWF had better scores than other products. However, products of all centers underestimated precipitation in high precipitation regions while overestimating precipitation in other regions. This points to a systematic bias in forecasts and demands application of bias correction techniques. Based on dichotomous evaluation, NCEP did better at most stations, although all centers overpredicted the number of precipitation events. Compared to those of ECMWF and NCER UKMO yielded higher scores in mountainous regions, but performed poorly at other selected stations. Furthermore, the evaluations showed that all centers had better skill in wet than in dry seasons. The quality of post-processed predictions was better than those of the raw predictions. In conclusion, the accuracy of the NWP predictions made by the selected centers could be classified as medium over Iran, while post-processing of predictions is recommended to improve the quality.
文摘In this study,the effect of different sampling rates(i.e.observation recording interval)on the Precise Point Positioning(PPP)solutions in terms of accuracy was investigated.For this purpose,a field test was carried out inÇorum province,Turkey,on 11 September 2019.Within this context,a Geodetic Point(GP)was established and precisely coordinated.A static GNSS measurement was occupied on the GP for about 4-hour time at 0.10 second(s)/10 Hz measurement intervals with the Trimble R10 geodetic grade GNSS receiver.The original observation file was converted to RINEX format and then decimated into the different data sampling rates as 0.2 s,0.5 s,1 s,5 s,10 s,30 s,60 s,and 120 s.All these RINEX observation files were submitted to the Canadian Spatial Reference System-Precise Point Positioning(CSRS-PPP)online processing service the day after the data collection date by choosing both static and kinematic processing options.In this way,PPP-derived static coordinates,and the kinematic coordinates of each measurement epoch were calculated.The PPP-derived coordinates obtained from each decimated sampling intervals were compared to known coordinates of the GP for northing,easting,2D position,and height components.According to the static and kinematic processing results,high data sampling rates did not change the PPP solutions in terms of accuracy when compared to the results obtained using lower sampling rates.The results of this study imply that it was not necessary to collect GNSS data with high-rate intervals for many surveying projects requiring cm-level accuracy.
基金the NHMRC Investigator grant fellowship (APP1176298)the EMCR grant from the Centre for Biomedical Technologies (QUT)+4 种基金the QUT Postgraduate Research Award (QUTPRA)QUT HDR TOP-UP scholarshipQUT HDR Tuition Fee Sponsorshipfunding support from the Academy of Finland (315820)the Jane and Aatos Erkko Foundation (190001).
文摘Osteoarthritis(OA)is a debilitating degenerative disease affecting multiple joint tissues,including cartilage,bone,synovium,and adipose tissues.OA presents diverse clinical phenotypes and distinct molecular endotypes,including inflammatory,metabolic,mechanical,genetic,and synovial variants.Consequently,innovative technologies are needed to support the development of effective diagnostic and precision therapeutic approaches.Traditional analysis of bulk OA tissue extracts has limitations due to technical constraints,causing challenges in the differentiation between various physiological and pathological phenotypes in joint tissues.This issue has led to standardization difficulties and hindered the success of clinical trials.Gaining insights into the spatial variations of the cellular and molecular structures in OA tissues,encompassing DNA,RNA,metabolites,and proteins,as well as their chemical properties,elemental composition,and mechanical attributes,can contribute to a more comprehensive understanding of the disease subtypes.Spatially resolved biology enables biologists to investigate cells within the context of their tissue microenvironment,providing a more holistic view of cellular function.Recent advances in innovative spatial biology techniques now allow intact tissue sections to be examined using various-omics lenses,such as genomics,transcriptomics,proteomics,and metabolomics,with spatial data.This fusion of approaches provides researchers with critical insights into the molecular composition and functions of the cells and tissues at precise spatial coordinates.Furthermore,advanced imaging techniques,including high-resolution microscopy,hyperspectral imaging,and mass spectrometry imaging,enable the visualization and analysis of the spatial distribution of biomolecules,cells,and tissues.Linking these molecular imaging outputs to conventional tissue histology can facilitate a more comprehensive characterization of disease phenotypes.This review summarizes the recent advancements in the molecular imaging modalities and methodologies for in-depth spatial analysis.It explores their applications,challenges,and potential opportunities in the field of OA.Additionally,this review provides a perspective on the potential research directions for these contemporary approaches that can meet the requirements of clinical diagnoses and the establishment of therapeutic targets for OA.
文摘The equations ofstate of the neutron star matter are calculated in the relativistic mean-field approximation witl different hyperon coupling constants. The properties of neutron stars are studied by solving the OppenheimerVolkoff equation. It manifests the properties of neutron stars - change explicitly as different hyperon coupling constants are concerned.
文摘In the present study, fracture toughness of functionally graded steels in crack divider configuration has been modeled. By utilizing plain carbon and austenitic stainless steels slices with various thicknesses and arrangements as electroslag remelting electrodes, functionally graded steels were produced. The fracture toughness of the functionally graded steels in crack divider configuration has been found to depend on the composites＇ type together with the volume fraction and the position of the containing phases. According to the area under stress-strain curve of each layer in the functionally graded steels, a mathematical model has been presented for predicting fracture toughness of composites by using the rule of mixtures. The fracture toughness of each layer has been modified according to the position of that layer where for the edge layers, net plane stress condition was supposed and for the central layers, net plane strain condition was presumed. There is a good agreement between experimental results and those acquired from the analytical model.
基金Henan Province Foundation of China,No.202300410307 and No.212102310611Xinxiang City Foundation of China,No.GG2020009.
文摘BACKGROUND Type 1 diabetes(T1D),a chronic metabolic and autoimmune disease,seriously endangers human health.In recent years,mesenchymal stem cell(MSC)transplantation has become an effective treatment for diabetes.Menstrual bloodderived endometrial stem cells(MenSC),a novel MSC type derived from the decidual endometrium during menstruation,are expected to become promising seeding cells for diabetes treatment because of their noninvasive collection procedure,high proliferation rate and high immunomodulation capacity.AIM To comprehensively compare the effects of MenSC and umbilical cord-derived MSC(UcMSC)transplantation on T1D treatment,to further explore the potential mechanism of MSC-based therapies in T1D,and to provide support for the clinical application of MSC in diabetes treatment.METHODS A conventional streptozotocin-induced T1D mouse model was established,and the effects of MenSC and UcMSC transplantation on their blood glucose and serum insulin levels were detected.The morphological and functional changes in the pancreas,liver,kidney,and spleen were analyzed by routine histological and immunohistochemical examinations.Changes in the serum cytokine levels in the model mice were assessed by protein arrays.The expression of target proteins related to pancreatic regeneration and apoptosis was examined by western blot.RESULTS MenSC and UcMSC transplantation significantly improved the blood glucose and serum insulin levels in T1D model mice.Immunofluorescence analysis revealed that the numbers of insulin+and CD31+cells in the pancreas were significantly increased in MSC-treated mice compared with control mice.Subsequent western blot analysis also showed that vascular endothelial growth factor(VEGF),Bcl2,Bcl-xL and Proliferating cell nuclear antigen in pancreatic tissue was significantly upregulated in MSC-treated mice compared with control mice.Additionally,protein arrays indicated that MenSC and UcMSC transplantation significantly downregulated the serum levels of interferonγand tumor necrosis factorαand upregulated the serum levels of interleukin-6 and VEGF in the model mice.Additionally,histological and immunohistochemical analyses revealed that MSC transplantation systematically improved the morphologies and functions of the liver,kidney,and spleen in T1D model mice.CONCLUSION MenSC transplantation significantly improves the symptoms in T1D model mice and exerts protective effects on their main organs.Moreover,MSC-mediated angiogenesis,antiapoptotic effects and immunomodulation likely contribute to the above improvements.Thus,MenSC are expected to become promising seeding cells for clinical diabetes treatment due to their advantages mentioned above.
文摘Time for single vehicle combat preparation(TSVCP) is an important characteristic parameter for the operational support feature of armored vehicle. During the development phase, how to validate the TSVCP of armored vehicle through analytic method is a difficult issue in analysis and validation of vehicle supportability.This paper uses Monte Carlo approach and builds a working model for single vehicle combat preparation(SVCP)of armored vehicle, thus realizes the prediction and analysis of the TSVCP of armored vehicle, and finally validates the effectiveness of the approach by example.
文摘Objective:The activity of enzymes participating in the systems of antioxidant protection was assayed in the peel and pulp of sunflower.The essential roles of proteases in food stimulate research to find other sources of the enzyme especially from non-conventional sources.In the present work,we study several biochemical parameters in the pulp and peel of sunflower.Methods:Pulp and peel of sunflower was extracted,antioxidant enzymes and nonenzymatic antioxidant were measured.Alkaline protease was measured and purified from pulp in sunflower.Results:High carbohydrate concentration,beta-carotene,catalase and ascorbate peroxidase activities,free radical scavenging capacity and free flavonoid content were observed in the peel of sunflower.Whereas,MDA and ceruloplasmin activities were high in the pulp of sunflower.Conclusions:The present study concluded that peel in sunflower are strong radical scavengers and can be considered as good sources of natural antioxidants for medicinal and commercial uses.Further analysis showed that protease activity was a significantly high in the pulp compared to the peel.
基金Supported by the National Natural Science Foundation of China under Grant No 10675014. I am grateful to Protessor K. Burnett at Oxford University and Professor M. Lewenstein at the Institut de Ciencies Fotoniques for useful discussions. Acknowledgments are also made to B. S. Zhao at Xi＇an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, D. X. Jiang, Y. L. Ye and J. X. Chen at Peking University for discussions, and Haip- ing He for her assistance.
文摘Quantitative investigations are made for the laser-duration dependence of the emission properties of high-order harmonic generation （HHG）. HHG emission properties produced by few-cycle lasers show some useful characteristics. The cutoff energy is less than that by laser for infinite duration. The single energy distribution pulse decreases much faster than its duration as the laser duration grows. A two-cycle laser with carrier-envelope phase of 0° can produce a single distribution pulse peaked at the laser carrier phase 1.22 rad and spanned 1.18 rad with the cutoff energy 2.9Up ＋ Ip and a bandwidth 0.63Up, where Up is the ponderomotive potential of the laser field and Ip is the atomic ionization potential.
文摘For the disadvantages of analyzing system reliability using common Bayes method,an evaluation method based on improved Bayes-Bootstrap method is presented.Firstly,the data obliteration problem existing in traditional Bayes method is analyzed,then an improved sampling arithmetic is proposed on the foundation of an experience function.Finally,effectiveness of this method is proved by an example.The simulating result shows that this method is more accurate than common Bayes method.
文摘In this study,the microstructure and mechanical properties of a multi-layered 316L-TiC composite material produced by selective laser melting(SLM)additive manufacturing process are investigated.Three different layers,consisting of 316L stainless steel,316L-5 wt%TiC and 316L-10 wt%TiC,were additively manufactured.The microstructure of these layers was characterized by optical microscopy(OM)and scanning electron microscopy(SEM).X-ray diffraction(XRD)was used for phase analysis,and the mechanical properties were evaluated by tensile and nanoindentation tests.The microstructural observations show epitaxial grain growth within the composite layers,with the elongated grains growing predominantly in the build direction.XRD analysis confirms the successful incorporation of the TiC particles into the 316L matrix,with no unwanted phases present.Nanoindentation results indicate a significant increase in the hardness and modulus of elasticity of the composite layers compared to pure 316L stainless steel,suggesting improved mechanical properties.Tensile tests show remarkable strength values for the 316L-TiC composite samples,which can be attributed to the embedded TiC particles.These results highlight the potential of SLM in the production of multi-layer metal-ceramic composites for applications that require high strength and ductility of metallic components in addition to the exceptional hardness of the ceramic particles.
文摘This article focuses on the performance analysis of both real-time and post-mission kinematic precise point positioning(PPP)in challenging marine environments.For this purpose,a real dynamic experiment lasting 6 h was carried out on a lake dam in?orum City of Turkey.While the kinematic test was continuing,the real-time PPP coordinates were obtained for each measurement epoch with a commercial real-time PPP(RT-PPP)service,namely the Trimble Center Point RTX.Then the post-mission PPP(PM-PPP)coordinates were calculated by using Multi-GNSS data and the Multi-GNSS Experiment(MGEX)precise products.The kinematic RT-PPP and PM-PPP results showed that the PPP coordinates were consistent with the relative solution at centimetre and decimetre level in horizontal and height components,respectively.This study implies that PPP technique is a powerful tool for highly accurate positioning in both real-time and post-mission modes,even for dynamic applications in harsh environments.
文摘The new numerical approach for analysis of the warhead transportations is suggested.This approach allows to control the warhead operability before its experimental analysis.The approach is implemented by the adequate models for the software ANSYS.Analysis of the loads at land operations and transportations of the warhead by natural roads,water and aviation allows to obtain the maximal values of loads,which are used in numerical simulations of the warhead.These loads give an opportunity to analyze the operability and the fatigue strength of the cartridge warhead.The numerical simulations of the attachments of the warhead combat elements are performed on the basis of the suggested method.The data of the numerical simulations verifies the operability of the fastener system of the warhead combat elements.
