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Review of Two Years of Surgical Activities of the General Surgery Department of the Reference Health Center of Commune I of Bamako Mali
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作者 Tounkara Cheickna Cisse Amadou Beydi +5 位作者 Samake Hamidou Diarra Issaka Sanogo Modibo Diarra Bogoba Doumbia Seydou Yena Sadio 《Surgical Science》 2024年第4期195-206,共12页
The objectives of this work were to evaluate the surgical activities carried out in the general surgery department of the Reference Health Center of Commune I of Bamako, to describe the sociodemographic characteristic... The objectives of this work were to evaluate the surgical activities carried out in the general surgery department of the Reference Health Center of Commune I of Bamako, to describe the sociodemographic characteristics of the operated patients, to determine the main pathologies encountered and to evaluate qualitatively the result of the treatment. In order to improve performance, and the quality of care, and to identify common pathologies in the surgical department, we undertook a retrospective study on surgical activities from January 2009 to December 2010. At the end of this study, out of 474 men and 187 women (equal sex ratio 2.53);we were able to determine the frequency of surgical pathologies. Farmers, housewives and pupils/students were the most represented with 25.9% respectively;20% and 13.3%. The most frequently observed pathologies were wall hernia (44.8%), prostate adenoma (12%) and acute appendicitis (10.5%). The average length of hospitalization was 3.43 days. Infectious complications affected 25 patients (3.8% of cases) and a death rate of 0.45% (i.e. 3 patients). The average cost of care was 53,500 FCFA. Indeed, the reality of surgical practice in health centers was not the same because of the level of skills of practicing surgeons. 展开更多
关键词 Assessment Surgical Activities 2 Years Reference Health Center of Commune I BAMAKO
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Intestinal Resection: Indications and Prognostic Factors at the General Surgery Department of Kankan Regional Hospital
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作者 Koundouno Aly Mampan Fofana Housein +12 位作者 Bah Mamadou Foinké Koundouno Saa Amadou Leno Tamba Keita Lancinè Fanta Koivogui Yaraboye Camara Sékou Tiguidan Koundouno Samuel Sanoh Lamine Doumbouya Moussa Cherif Mamady Sacko Mamoudou Sano Amara Thiam Mohamed 《Surgical Science》 2024年第11期588-597,共10页
Introduction: Intestinal resection is the disconnection or removal of part of the intestine with its meso. The aim was to describe the indications and prognostic factors for intestinal resections at the surgical depar... Introduction: Intestinal resection is the disconnection or removal of part of the intestine with its meso. The aim was to describe the indications and prognostic factors for intestinal resections at the surgical department of Kankan Regional Hospital. Patients and Methods: This was a retrospective descriptive study covering the files of patients who had undergone intestinal resections in the surgery department of the Kankan regional hospital over a period of 4 years from 1st January 2019 to December 31, 2022. Results: We collected 164 cases of intestinal resection representing 4.19% of all surgical procedures. (N = 3909). The average age of our patients was 37.78 years with extremes of 1 and 90 years. The male gender was predominant (64.6%) and the sex ratio was 1.8. The majority of patients consulted after 72 hours. Acute intestinal obstruction was the pathology motivating the most intestinal resection 42.90% followed by acute peritonitis 33%, digestive fistula 4.3%, tumors 3.6% and wounds 2.4%. Intestinal necrosis with 91 cases (56.5%) constituted the first indication for resection in our study followed by intestinal perforations 41 cases (24.9%). We performed an anastomotic resection of the small intestine in 70 cases (42.9%), an ileostomy in 4 cases (2.4%), a right hemi colectomy in 26 cases (15.9%), a left hemi colectomy in 2 cases (1.2%), segmental colectomy plus immediate anastomosis in 57 cases (34.2%) and 5 cases of colostomy. We recorded 48 deaths (29.3%). Conclusion: Intestinal resection is a common procedure in our context. These indications are multiple. An improvement in the prognosis should be achieved by reducing the diagnostic and treatment time associated with the training of surgical staff. 展开更多
关键词 Intestinal Resection ANASTOMOSIS INDICATION MORTALITY
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Diagnostic yield of follow-up in patients undergoing surgery for nonmetastatic colorectal cancer 被引量:2
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作者 Noelia Sala-Miquel JoséCarrasco-Muñoz +9 位作者 Soledad Bernabeu-Mira Carolina Mangas-Sanjuan Sandra Baile-Maxía Lucía Madero-Velázquez Victor Ausina Ana Yuste Lucía Gómez-González Manuel Romero Simó Pedro Zapater Rodrigo Jover 《World Journal of Gastroenterology》 2025年第12期37-48,共12页
AIM To analyze the diagnostic performance of surveillance colonoscopy,computed tomography(CT),and tumor markers(TMs)in detecting CRC recurrence or metastasis during follow-up after CRC resection.Secondary objectives i... AIM To analyze the diagnostic performance of surveillance colonoscopy,computed tomography(CT),and tumor markers(TMs)in detecting CRC recurrence or metastasis during follow-up after CRC resection.Secondary objectives included degree of adherence to clinical practice guidelines surveillance recommendations and factors associated with adherence and all-cause and CRC mortality.METHODS The single-center retrospective cohort study including patients undergoing curative resection of stage I-III CRC during 2010-2015.Follow-up was performed using TMs every 6 months,yearly CT for 5 years,and colonoscopy at years 1 and 4.Demographic,primary tumor data,and results at follow-up were collected.RESULTS Of 574 included patients included,153 had recurrences or metastases.Of this group,136(88.9%)were diagnosed by CT,10(6.5%)by CT and colonoscopy,and 7(4.6%)by colonoscopy;only 67.8%showed TMs elevation.Adherence to follow-up recommendations was 68.8%for the first colonoscopy,74%for the first CT scan,and 96.6%for the first blood test;these values declined over time.Younger age at diagnosis[odds ratio(OR)0.93;95%CI:0.91-0.95],CRC stages I-II(OR 0.38;95%CI:0.24-0.61),and adherence to follow-up recommendations(OR 0.30;95%CI:0.20-0.46)were independently associated with lower risk for all-cause death at 5 years.CONCLUSION CT scan had the highest diagnostic yield.Adherence to follow-up recommendations was low and decreased during follow-up.Younger age at diagnosis,stage,and follow-up adherence were associated with lower 5-year mortality. 展开更多
关键词 Colorectal cancer SURVEILLANCE RECURRENCE Tumor markers COLONOSCOPY Computed tomography
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Current Epidemiology of Intracranial Metastases in Two University Teaching Reference Hospitals of the Town of Yaounde, Cameroon: Analysis of 35 Cases Recorded in the Neurosurgery Departments
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作者 Nassourou Oumarou Haman Ronaldo Fonju Anu +4 位作者 Orlane Ndome Toto Bello Figuim Indira Baboke Marguerite Gwladys Nzedzou Vincent de Paul Djientcheu 《Open Journal of Modern Neurosurgery》 2024年第2期124-136,共13页
Background: The incidence of intracranial metastases (ICMET) has been steadily rising, and its frequency with respect to primary brain tumours is relatively high. Objective: The objectives of this study were to elucid... Background: The incidence of intracranial metastases (ICMET) has been steadily rising, and its frequency with respect to primary brain tumours is relatively high. Objective: The objectives of this study were to elucidate the current epidemiology and describe the clinical, diagnostic and therapeutic features of ICMET in Yaounde. Method and findings: A descriptive cross-sectional study was done in the neurosurgery departments of the General and Central Hospitals of Yaounde during the period from January 2016 to December 2022. We included all medical booklets of patients admitted for a tumoral intracranial expansive process with our target population being patients with histological evidence of ICMET, and did a retrospective inclusion of data using a pre-established technical form aimed at collecting sociodemographic data, clinical data, paraclinical data, and the treatment procedures. Analysis was done using the SPSS statistical software. A total of 614 cases of intracranial tumors were included among whom 35 presented histological evidence of ICMET. This gives a frequency of 5.7%. The sex ratio was 0.94, the mean age was 55.68 +/- 14.4 years, extremes 28 and 86 years and the age range 50 - 59 was affected in 28.57% of cases. The clinical presentation included signs of raised intracranial pressure (headache, blurred vision, vomiting) in 26 cases (74.3%), motor deficit 48.6%, seizures 17.1%. The mode of onset was metachronous in 71.4% and synchronous in 28.6%. The imaging techniques were cerebral CT scan in 82.9%, cerebral MRI in 40%, TAP scan in 22.9%. The metastatic lesions were supratentorial in 94.3% and single in 62.9%. The primary cancers found were breast cancer (31.4%), lung cancer (25.7%), prostate cancer (17.1%), thyroid cancer (5.7%), colon cancer (2.9%), and melanoma (2.9%). The therapeutic modalities were total resection (68.6%), radiotherapy (37.1%). Conclusion: Intracranial metastases are relatively frequent. There is a female sex predominance and the age group 50 - 59 years is the most affected. Brain metastases mostly occur in patients with a history of known primary tumor. The clinical signs mainly include signs of raised intracranial pressure, motor deficit, seizures and mental confusion. Cerebral CT Scan is the main imaging technique used. Most of the lesions are single and supratentorially located. The primary cancers most represented include breast cancer, lung cancer and prostate cancer. Surgery is the main treatment procedure. The adjuvant treatment (radiotherapy, chemotherapy) was limited. 展开更多
关键词 Intracranial Metastases EPIDEMIOLOGY Yaounde
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Minimally invasive surgery for colorectal cancer emergencies
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作者 Neng-Wei Wong Salman Ahmed Abdul Jabbar +1 位作者 James Chi-Yong Ngu Nan-Zun Teo 《World Journal of Clinical Oncology》 2025年第8期71-82,共12页
Colorectal cancer(CRC)is a leading cause of cancer-related morbidity and mortality globally,and its management in the emergency setting presents distinct challenges.In addition to its advantages in elective CRC surger... Colorectal cancer(CRC)is a leading cause of cancer-related morbidity and mortality globally,and its management in the emergency setting presents distinct challenges.In addition to its advantages in elective CRC surgery,studies have demonstrated that minimally invasive surgery(MIS)can provide benefits in CRC emergencies,such as reduced morbidity and a shorter length of hospitalization.However,the applicability of MIS in the emergency setting is limited by factors such as compromised patient physiology,resource constraints,and the need for technical expertise.As an alternative to emergency MIS,endoscopic interventions have also been increasingly supported by emerging evidence as a bridge to surgery.This article appraises contemporary guidelines and the evidence behind their recommendations for MIS surgery in CRC emergencies,whilst highlighting the challenges to implementation and the strategies to overcome them. 展开更多
关键词 Colorectal malignancy Colorectal cancer emergency Minimally invasive surgery Laparoscopic Robotic Obstructed colorectal cancer Perforated colorectal cancer Bleeding colorectal cancer
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Endoscopic retrograde cholangiopancreatography-related adverse events:What is the role of surgery today?
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作者 Mariarita Tarallo Daniele Crocetti +4 位作者 Alessandro Coppola Immacolata Iannone Antonietta Lamazza Paolo Sapienza Enrico Fiori 《World Journal of Gastrointestinal Surgery》 2025年第7期108-115,共8页
Endoscopic retrograde cholangiopancreatography(ERCP)plays a vital role in managing biliary and pancreatic diseases but carries a risk of severe complications that may require surgical intervention.This review focuses ... Endoscopic retrograde cholangiopancreatography(ERCP)plays a vital role in managing biliary and pancreatic diseases but carries a risk of severe complications that may require surgical intervention.This review focuses on the surgical management of key ERCP-related complications:Post-sphincterotomy bleeding,perforations,stent migration-induced perforations,and Dormia basket impaction.Although many complications can be managed endoscopically,surgery remains essential in refractory cases or when less invasive methods fail.Post-sphincterotomy bleeding,although often controlled endoscopically,may necessitate surgical ligation when hemorrhage persists.Perforations,classified by anatomical type,require tailored surgical approaches-primary repair for type I and biliary diversion with defect closure for types II and III.Stent migration-induced perforations,which may lead to peritonitis or abscess formation,often require surgery due to their variable clinical presentation and the lack of standardized management guidelines.Dormia basket impaction,although rare,may require advanced endoscopic techniques or laparoscopic retrieval if conservative measures prove ineffective.Early recognition,multidisciplinary collaboration,and individualized treatment strategies are pivotal in reducing morbidity and mortality.This review underscores evolving surgical approaches,emphasizing the importance of timely,patient-specific decisions to improve outcomes in severe ERCP-related complications. 展开更多
关键词 Endoscopic retrograde cholangiopancreatography complications Surgical management Post-sphincterotomy bleeding PERFORATION Stent migration Dormia basket impaction
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Revolutionizing hepatobiliary surgery:Impact of three-dimensional imaging and virtual surgical planning on precision,complications,and patient outcomes
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作者 Himanshu Agrawal Himanshu Tanwar Nikhil Gupta 《Artificial Intelligence in Gastroenterology》 2025年第1期39-51,共13页
BACKGROUND Hepatobiliary surgery is complex and requires a thorough understanding of the liver’s anatomy,biliary system,and vasculature.Traditional imaging methods such as computed tomography(CT)and magnetic resonanc... BACKGROUND Hepatobiliary surgery is complex and requires a thorough understanding of the liver’s anatomy,biliary system,and vasculature.Traditional imaging methods such as computed tomography(CT)and magnetic resonance imaging(MRI),although helpful,fail to provide three-dimensional(3D)relationships of these structures,which are critical for planning and executing complicated surgeries.AIM To explore the use of 3D imaging and virtual surgical planning(VSP)technologies to improve surgical accuracy,reduce complications,and enhance patient recovery in hepatobiliary surgeries.METHODS A comprehensive review of studies published between 2017 and 2024 was conducted through PubMed,Scopus,Google Scholar,and Web of Science.Studies selected focused on 3D imaging and VSP applications in hepatobiliary surgery,assessing surgical precision,complications,and patient outcomes.Thirty studies,including randomized controlled trials,cohort studies,and case reports,were included in the final analysis.RESULTS Various 3D imaging modalities,including multidetector CT,MRI,and 3D rotational angiography,provide high-resolution views of the liver’s vascular and biliary anatomy.VSP allows surgeons to simulate complex surgeries,improving preoperative planning and reducing complications like bleeding and bile leaks.Several studies have demonstrated improved surgical precision,reduced complications,and faster recovery times when 3D imaging and VSP were used in complex surgeries.CONCLUSION 3D imaging and VSP technologies significantly enhance the accuracy and outcomes of hepatobiliary surgeries by providing individualized preoperative planning.While promising,further research,particularly randomized controlled trials,is needed to standardize protocols and evaluate long-term efficacy. 展开更多
关键词 Three-dimensional imaging Virtual surgical planning Hepatobiliary surgery Surgical precision Preoperative planning
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Impact of robotic surgery proportion among minimally invasive gastrectomy on surgical complications
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作者 Jeong Ho Song Yeojin Boo +3 位作者 Sang-Yong Son Hoon Hur Sang-Uk Han Information Committee of the Korean Gastric Cancer Association 《Chinese Journal of Cancer Research》 2025年第2期200-211,共12页
Objective:The Safety of robotic gastrectomy(RG)compared to laparoscopic gastrectomy(LG)for gastric cancer remains uncertain on a national scale,with limited comparative studies across institutions.This study aims to c... Objective:The Safety of robotic gastrectomy(RG)compared to laparoscopic gastrectomy(LG)for gastric cancer remains uncertain on a national scale,with limited comparative studies across institutions.This study aims to compare the morbidity rates between RG and LG using data from a nationwide survey.Methods:We utilized data from the Korean Gastric Cancer Association's 2019 nationwide survey.The proportion of robotic surgeries in minimally invasive surgery at each institution was classified using a cut-off value of 10%,and defined as high robotic proportion cohort and low robotic proportion cohort.We analyzed surgical outcomes between robotic and laparoscopic gastrectomy in each cohort using propensity score matching(PSM).To account for potential clustering effects within hospitals,we employed Generalized Estimating Equations with hospital as the clustering variable.Results:This study included 776 patients who underwent RG and 7,804 patients who underwent LG for gastric cancer.In low robotic proportion cohort,RG had a longer operation time(P<0.001)but similar blood loss(P=0.792)compared to LG.In the high robotic proportion cohort,RG showed longer operation time(P<0.001),less blood loss(P<0.001),and shorter hospital stays(P<0.001)compared to LG.Additionally,RG in the high robotic proportion cohort had shorter operative time(P<0.001)and less blood loss(P=0.024)compared with that in the low robotic proportion cohort.Conclusions:RG demonstrated comparable perioperative outcomes to LG in a nationwide PSM analysis.However,RG offers limited benefits over LG at institutions with lower frequencies of RG use. 展开更多
关键词 COMPLICATION LAPAROSCOPY GASTRECTOMY gastric cancer ROBOT
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Elevating surgical standards:The role of intraperitoneal isoperistaltic side-to-side anastomosis in colon cancer surgery
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作者 Sung Uk Bae 《World Journal of Gastrointestinal Oncology》 2025年第6期516-520,共5页
Since its introduction in 1991,laparoscopic right colectomy has been the standard surgical treatment for benign and malignant right colon diseases.Extracorporeal anastomosis(ECA)is the most commonly used anastomotic t... Since its introduction in 1991,laparoscopic right colectomy has been the standard surgical treatment for benign and malignant right colon diseases.Extracorporeal anastomosis(ECA)is the most commonly used anastomotic technique.However,intracorporeal anastomosis(ICA)has emerged as a promising alternative because of its potential advantages.Recently,Wu et al provided compelling evidence supporting superiority of ICA over ECA,demonstrating reduced blood loss,smaller incisions,and faster postoperative recovery without increased complic-ations.Despite these benefits,ICA presents certain challenges such as longer operative times and technical difficulties.However,advances in minimally in-vasive surgery,including robot-assisted platforms,may facilitate broader adoption of ICA by addressing the technical limitations.Furthermore,meticulous surgical techniques and perioperative infection control strategies are essential for mitigating intra-abdominal infectious complications.Given the increasing adoption of ICA in minimally invasive right hemicolectomy,further studies,including multicenter randomized controlled trials,are necessary to confirm its oncological safety and establish standardized surgical protocols.Overall,ICA has the potential to become the preferred anastomotic approach in both laparoscopic and robotic colorectal surgeries. 展开更多
关键词 Colon cancer Laparoscopic surgery Intraperitoneal anastomosis Extraperitoneal anastomosis Isoperistaltic side-to-side anastomosis
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Enhanced recovery after surgery protocols in gastrectomy with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for gastric cancer
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作者 Chawisa Nampoolsuksan Thammawat Parakonthun 《World Journal of Clinical Oncology》 2025年第8期58-70,共13页
Gastric cancer with peritoneal carcinomatosis(PC)remains a formidable challenge in oncological care,especially regarding surgical intervention.Integrating enhanced recovery after surgery(ERAS)protocols into gastrectom... Gastric cancer with peritoneal carcinomatosis(PC)remains a formidable challenge in oncological care,especially regarding surgical intervention.Integrating enhanced recovery after surgery(ERAS)protocols into gastrectomy with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy has emerged as a promising approach.This minireview explores the influence of ERAS on surgical and oncological outcomes in this multifaceted procedure.Recent evidence suggests that ERAS,comprising multimodal strategies,improves postoperative recovery,reduces complications,and enhances quality of life.It may also contribute to better survival outcomes by minimizing perioperative morbidity and thereby facilitating the timely initiation of adjuvant therapy.Mechanistically,ERAS promotes early mobilization,attenuates postoperative immunosuppression,and supports timely adjuvant therapies,which are crucial in managing carcinomatosis.This minireview underscores the importance of multidisciplinary collaboration and individualized patient care to maximize ERAS benefits.Large-scale,prospective investigations are warranted to validate these findings and refine ERAS protocols for this specialized patient cohort.Further research will facilitate ongoing advancements in oncological surgery and perioperative care,ultimately improving outcomes for patients with gastric cancer and PC. 展开更多
关键词 Cytoreductive surgery Enhanced recovery after surgery Gastric cancer Hyperthermic intraperitoneal chemotherapy Peritoneal carcinomatosis
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Current roles of colonoscopy in minimally invasive colorectal surgery:Preoperative guidance,intraoperative colonoscopy,and combined endoscopic-laparoscopic surgery
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作者 Yuuri Hatsuzawa Shingo Tsujinaka +6 位作者 Tomoya Miura Yoh Kitamura Atsushi Mitamura Kentaro Sawada Makoto Hikage Toru Nakano Chikashi Shibata 《World Journal of Gastrointestinal Endoscopy》 2025年第11期23-31,共9页
Colonoscopy is a cornerstone in the detection and diagnosis of colorectal tumors,playing a critical role in both screening and clinical evaluation. More recently, itsutility has expanded to therapeutic guidance, parti... Colonoscopy is a cornerstone in the detection and diagnosis of colorectal tumors,playing a critical role in both screening and clinical evaluation. More recently, itsutility has expanded to therapeutic guidance, particularly with the advent ofminimally invasive surgical techniques. Preoperative tattoo marking is commonlyused for tumor localization;however, it poses challenges such as intraperitonealink scattering and difficulty in defining dissection planes in the lower rectum. Toaddress these limitations, a new technology utilizing a near-infrared fluorescenceclip placed preoperatively enables accurate intraoperative tumor localization.Intraoperative colonoscopy offers additional advantages, including real-timetumor localization, colonic irrigation, visualization of the proximal colon inobstructive cases, and assessment of anastomosis following colorectal resection.Notably, intraoperative colonoscopy allows for the immediate detection andmanagement of complications, such as anastomotic bleeding and leakage, potentiallyimproving postoperative outcomes. Furthermore, advances in endoscopicresections, including endoscopic mucosal resection, endoscopic submucosal dissection,hybrid endoscopic submucosal dissection, and combined endoscopiclaparoscopic surgery, have broadened the indications for endoscopic and endoscopy-guided full-thickness resection of colorectal tumors. These approaches areincreasingly applicable beyond conventional colorectal neoplasms and showpromise in managing appendiceal tumors as well. 展开更多
关键词 Intraoperative colonoscopy Tumor localization Anastomotic integrity Synchronous lesion Endoscopic mucosal resection Endoscopic submucosal dissection Combined endoscopic laparoscopic surgery Laparoscopy and endoscopy cooperative
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Artificial intelligence in gastrointestinal surgery:A minireview of predictive models and clinical applications
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作者 Himanshu Agrawal Nikhil Gupta +1 位作者 Himanshu Tanwar Natasha Panesar 《Artificial Intelligence in Gastroenterology》 2025年第1期52-73,共22页
BACKGROUND Artificial intelligence(AI)is playing an increasingly significant role in predicting outcomes of gastrointestinal(GI)surgeries,improving preoperative risk assessment and post-surgical decision-making.AI mod... BACKGROUND Artificial intelligence(AI)is playing an increasingly significant role in predicting outcomes of gastrointestinal(GI)surgeries,improving preoperative risk assessment and post-surgical decision-making.AI models,particularly those based on machine learning,have demonstrated potential in predicting surgical complications and recovery trajectories.AIM To evaluate the role of AI in predicting outcomes for GI surgeries,focusing on its efficacy in enhancing surgical planning,predicting complications,and optimizing post-operative care.METHODS A systematic review of studies published up to March 2025 was conducted across databases such as PubMed,Scopus,and Web of Science.Studies were included if they utilized AI models for predicting surgical outcomes,including morbidity,mortality,and recovery.Data were extracted on the AI techniques,performance metrics,and clinical applicability.RESULTS Machine learning models demonstrated significantly better performance than logistic regression models,with an area under the curve difference of 0.07(95%CI:0.04–0.09;P<0.001).Models focusing on variables such as patient demographics,nutritional status,and surgical specifics have shown improved accuracy.AI’s ability to integrate multifaceted data sources,such as imaging and genomics,contributes to its superior predictive power.AI has improved the early detection of gastric cancer,achieving 95%sensitivity in real-world settings.CONCLUSION AI has the potential to transform GI surgical practices by offering more accurate and personalized predictions of surgical outcomes.However,challenges related to data quality,model transparency,and clinical integration remain. 展开更多
关键词 Artificial intelligence Gastrointestinal surgery Outcome prediction Machine learning Postoperative complications
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Effects of preoperative immunonutrition vs standard oral nutrition in patients undergoing colorectal surgery:A randomized controlled trial
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作者 Manivaasan Pannirselvam Zaidi Zakaria +4 位作者 Michael Pak-Kai Wong Mohd Hady Shukri Abdul Satar Nor Syarahani Jusoh Andee Dzulkarnaen Zakaria Muhammad Faeid Othman 《World Journal of Gastrointestinal Surgery》 2025年第9期333-342,共10页
BACKGROUND Current guidelines recommend providing malnourished individuals immunonutrition before major gastrointestinal surgery.Nonetheless,the advantages of preoperative immunonutrition remain controversial.AIM To a... BACKGROUND Current guidelines recommend providing malnourished individuals immunonutrition before major gastrointestinal surgery.Nonetheless,the advantages of preoperative immunonutrition remain controversial.AIM To analyses the effects of preoperative immunonutrition and standard oral nutrition supplements on colorectal surgery outcomes.METHODS This study employed a prospective single-center randomized double-blinded comparative approach and was conducted at Hospital Universiti Sains Malaysia between September 2023 and September 2024.In this study,the participants in the experimental group were supplied with a specialized oral supplement enriched with immune-modulating nutrients.Meanwhile,a conventional oral nutrition supplement was provided to the control group.The time to first flatus and the time to first bowel evacuation were the primary outcomes recorded.Incidence of nosocomial infections,surgical site infections,and the total length of hospital stay were considered secondary data.RESULTS This study involved 58 patients who were allocated into two groups.No dropouts were documented.The mean age of the participants was 61.20±12.96,and most were males(63.38%).All participants’baseline and surgical characteristics in both arms were also generally comparable.The participants in this study underwent colorectal surgery,where most had laparoscopic surgery(58%).Based on the results,no significant statistical differences were observed regarding the duration from the first flatus to the first bowel evacuation,the onset of a normal diet,and hospital stay between the experimental and control groups.Both groups also recorded 10(17.24%)infectious complications.CONCLUSION The findings indicated no notable variations in the primary and secondary endpoints despite the theoretical benefits of immune-modulating nutrients.Conclusively,routine preoperative immunonutrition may not provide additional advantages over standard nutrition in this demographic. 展开更多
关键词 Cancer surgery Colorectal surgery Gastrointestinal surgery IMMUNONUTRITION Postoperative complication
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Neoadjuvant treatment in resectable pancreatic cancer:Why is upfront surgery so hard to be beaten?
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作者 Pedro Luiz Serrano Uson Junior Kunal C Kadakia Raphael L C Araujo 《World Journal of Clinical Oncology》 2025年第9期148-156,共9页
Neoadjuvant treatment is being extensively evaluated in pancreatic ductal adenocarcinoma(PDAC).This interest is appropriate given the dismal long-term prognosis for most patients who undergo upfront surgery.Despite pr... Neoadjuvant treatment is being extensively evaluated in pancreatic ductal adenocarcinoma(PDAC).This interest is appropriate given the dismal long-term prognosis for most patients who undergo upfront surgery.Despite prospective,retrospective and randomized trials supporting the role of neoadjuvant therapy in general for PDAC,the long-term benefit specifically for patients with resectable PDAC remains unclear.The phase III PREOPANC trial showed an improvement in overall survival in borderline resectable PDAC with neoadjuvant gemcitabinebased chemoradiation compared to upfront surgery alone,however,no such benefit was observed in the resectable cohort.Notably,three randomized trials(PANACHE01-PRODIGE 48,NORPACT-1,and PREOPANC-2)failed to show a clear improvement in overall survival with a neoadjuvant approach.The ongoing NeoFOL-R,PREOPANC-3,and the Alliance A021806 will help clarify the role of neoadjuvant therapy in resectable PDAC.In this minireview article we summarize the data surrounding neoadjuvant therapy in resectable pancreatic cancer and discuss future considerations of trials in this subgroup. 展开更多
关键词 Pancreas cancer Neoadjuvant treatment CHEMOTHERAPY Radiation Therapy SURGERY PANCREATECTOMY
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Postoperative atrial fibrillation in emergent non-cardiac surgery:Risk factors and outcomes from a ten-year intensive-care unit retrospective study
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作者 Dimitrios Giannis Ruby Zhao +6 位作者 Luis Fernandez Nicole Nikolov Christina Sneed Patrick Kiarie Andrew Miele Martine A Louis Nageswara Rao Mandava 《World Journal of Critical Care Medicine》 2025年第3期207-221,共15页
BACKGROUND Atrial fibrillation(AF)represents a common arrhythmia with significant implications and may occur pre-,intra-,or postoperatively(POAF).After cardiac surgery POAF occurs in approximately 30% of patients,whil... BACKGROUND Atrial fibrillation(AF)represents a common arrhythmia with significant implications and may occur pre-,intra-,or postoperatively(POAF).After cardiac surgery POAF occurs in approximately 30% of patients,while non-cardiac/nonthoracic surgery has a reported incidence between 0.4% to 15%,with new onset POAF occurring at a rate of 0.4% to 3%.While AF has been extensively studied,it has not been well described in emergent non-cardiac surgery associated with increased surgical stress in an intensive care unit setting(ICU).AIM To investigate the incidence/predictors of POAF in emergent non-cardiac surgery and its associations with postoperative outcomes in the ICU.METHODS This retrospective study included patients≥18 years who underwent exploratory laparotomy or lower extremity amputation between October 2012 and September 2023 and were admitted in the ICU.Data of interest included occurrence of POAF,demographic characteristics,comorbidities,laboratory values,administered fluids,medications,and postoperative outcomes.Statistical analyses consisted of identifying predic-tors of POAF and associations of POAF with outcomes of interest.RESULTS A total of 347 ICU patients were included,16.4% had a history of AF,13.0% developed POAF,and 7.9%developed new-onset POAF.Patients with new-onset POAF were older(79.6±9.1 vs 68.1±14.8 years,<0.001),of white race(47.8%vs 28.8,P<0.001),hypertensive(87.0%vs 71.2%,P=0.011),had longer ICU length of stay(ICU-LOS)(13.4 vs 6.7 days,P=0.042),higher mortality(43.5%vs 17.6%,P=0.016)and higher rate of cardiac arrest(34.8%vs 14.6%,P=0.005)compared to patients without new-onset POAF.Multivariable analysis revealed increased POAF risk with advanced age(OR=1.06;95%CI:1.02-1.10,P=0.005),white race(OR=2.85;95%CI:1.26-6.76,P=0.014),high intraoperative fluid(OR>1;95%CI:1.00-1.00,P=0.018),and longer ICU-LOS(OR=1.04;95%CI:1.00-1.08,P=0.023).After adjusting for demographics,new onset POAF significantly predicted mortality(OR=3.07;95%CI:1.14-8.01,P=0.022).CONCLUSION POAF was associated with prolonged ICU-LOS,white race,and high intraoperative fluid.New-onset POAF was associated with increased risk of cardiac arrest and death in critically ill patients. 展开更多
关键词 Postoperative atrial fibrillation Non-cardiac surgery Intensive care unit Postoperative mortality Emergent surgery Exploratory laparotomy Knee amputation
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Fundamentals of digital surgery
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作者 Bin Zheng Xiujun Cai 《Laparoscopic, Endoscopic and Robotic Surgery》 2025年第3期115-122,共8页
Unlike earlier innovations that focused on manipulation and task precision,the latest surgical advancements emphasize data visualization and the acceleration of surgeons’decision-making.Before entering the operating ... Unlike earlier innovations that focused on manipulation and task precision,the latest surgical advancements emphasize data visualization and the acceleration of surgeons’decision-making.Before entering the operating room,digital tools help surgeons develop patient-specific approaches,outline procedural steps,and prepare strategies for managing potential crises.During the operation,relevant data appear at the right moment to assist decision-making and guide performance in formats tailored to the surgeon’s physical and cognitive state,all without causing distractions.In the future operating room,performance data from surgeons will be gathered,integrated,and analyzed to interpret surgeons’behavior and confidence.Advanced techniques,including artificial intelligence,can be employed to automatically detect moments of performance difficulty or cognitive overload.As a result,digital surgery provides timely,context-specific assistance to surgeons in high-stakes situations.Key components of digital surgery are highlighted in this narrative review. 展开更多
关键词 Digital surgery Three-dimensional model Presurgical planning Intraoperative performance Augmented reality Patient safety
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Removal of the sac during surgery for the repair of“giant”paraesophageal hernias
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作者 Vahe M Hakobyan Areg A Petrosyan +9 位作者 Hayk H Yeghiazaryan Andranik Y Aleksanyan Hayk H Safaryan Hakob H Shmavonyan Karen T Papazyan Khachik H Ayvazyan Levon G Davtyan Aram A Khachatryan Ghukas S Sargsyan Suren A Stepanyan 《World Journal of Gastrointestinal Surgery》 2025年第7期244-254,共11页
BACKGROUND The presence of a large paraesophageal hernia is a source of concern in foregut surgery.Thus,scholars have focused on ascertaining the optimal surgical approach,methods for reinforcing the esophageal hiatus... BACKGROUND The presence of a large paraesophageal hernia is a source of concern in foregut surgery.Thus,scholars have focused on ascertaining the optimal surgical approach,methods for reinforcing the esophageal hiatus,and strategies for preventing hernia recurrence and gastroesophageal reflux.AIM To investigate the outcomes of surgery for giant paraesophageal hernias without sac removal.METHODS Sixty-six consecutive patients who underwent surgery for a giant paraesophageal hernia between May 2010 and December 2024 were included in this retrospective study.The pre-and postoperative examinations included upper gastrointestinal endoscopy,X-ray with barium contrast swallow,contrast-enhanced computed tomography(CT)scans of the chest and abdomen,24-hour potential hydrogen esophageal monitoring,and esophagomanometry.The study group included 36 patients who underwent surgery without sac removal,and the control group included 30 patients who underwent surgery with sac removal.RESULTS Fifty-two patients(28 in the study group and 24 in the control group)underwent laparoscopic procedures,10(6 in the study group and 4 in the control group)underwent open procedures,and 4(2 in each group)underwent conversion procedures.The operative time and postoperative length of stay were significantly longer in the control group than in the study group.In 12 patients in the study group,X-ray examination on postoperative days 3-5 revealed air-fluid levels at the site of the remaining hernia sac;all air-fluid levels disappeared without intervention 2 months later.Postoperative day 60 CT and X-ray examinations revealed no pathological changes related to the hernia sac in the mediastinum.CONCLUSION Removal of the hernia sac during surgery for giant paraesophageal hernias is not mandatory.Further large-scale multicentric randomized trials are needed for a more detailed investigation in this field. 展开更多
关键词 Paraesophageal hernia Hiatal hernia Hernia repair Hernia sac Laparoscopic fundoplication
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Reducing invasiveness in liver surgery-where is the limit?
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作者 Ivan Romic Ivan Separovic +3 位作者 Dora Grgic Igor Petrovic Josip Mavrek Hrvoje Silovski 《World Journal of Gastrointestinal Surgery》 2025年第2期316-319,共4页
In this article,we comment on the article by Wang et al published in the recent issue of the World Journal of Gastroenterology Surgery.Most prominent advancements in liver surgery in the last two decades are related t... In this article,we comment on the article by Wang et al published in the recent issue of the World Journal of Gastroenterology Surgery.Most prominent advancements in liver surgery in the last two decades are related to refinements in surgical technique(extraglissonean approach)and advancements in surgical technology(laparoscopy and robotics).In this article,authors present both these aspects:Laparoscopic segmentectomy using extraglissonean approach.Furthermore,they describe segmental resections of all 8 segments which is the main novelty that can be observed in the article.By now,extraglissonean approach was thoroughly described mainly in hepatectomies or lateral sectionectomies.Various“hilar gates”are defined which allows safe liver resection by ligating Glissonean pedicles first which is then followed by parenchymal resection.We here focus on past,present and future perspectives of extraglissonean approach and laparoscopic liver resections and comment the value of the presented article. 展开更多
关键词 Liver resection LAPAROSCOPY Glissonean approach SEGMENTECTOMY
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Heart Valve Surgery in Cameroon:Background and Perspectives
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作者 William Ngatchou Sarah Heenen +20 位作者 Laurence Carole Ngo Yon Virginie Guimfacq Zephanie Kobe Fokalbo Alain Patrick Menanga Hermann Nestor Tsague Kegni Jérôme Bombhi Liliane Mfeukeu-Kuate Christian Ngongang Ouankou David Douglas Banga Nkomo Dzudié Anastase Félicité Kamdem Siddick Mouliom Viche Lade Valerie Ndobo Marie Solange Ebongue Ndom Junette Metogo Joseph Sango Aymard Kack Bilong Philippe Gottignies Diane-Estelle Ngatchou-Djomo Charles Mve Mvondo 《World Journal of Cardiovascular Diseases》 2025年第11期561-569,共9页
Acute rheumatic fever(ARF)and its sequela,rheumatic heart disease(RHD),remain major causes of morbidity and mortality in low-and middle-income countries,particularly in sub-Saharan Africa.In Cameroon,RHD accounts for ... Acute rheumatic fever(ARF)and its sequela,rheumatic heart disease(RHD),remain major causes of morbidity and mortality in low-and middle-income countries,particularly in sub-Saharan Africa.In Cameroon,RHD accounts for a considerable share of pediatric and adolescent heart disease.Severe valvular involvement often requires surgical intervention,but access to cardiac surgery is critically constrained.Since the 1980s,cardiac surgery in Cameroon has evolved from sporadic humanitarian missions to structured initiatives at the Douala and YaoundéGeneral Hospital and also the Shisong Cardiac Center.This article sheds light on the historical development and current state of cardiac surgery in Cameroon,emphasizing RHD as the leading surgical indication.It highlights both achievements and persistent gaps,and outlines perspectives for sustainability,including national training pathways,diaspora engagement,research and innovation,public-private partnerships,and South-South collaboration.Strengthening local capacity,securing sustainable financing mechanisms such as universal health coverage,and fostering regional cooperation are essential to build autonomous,resilient cardiac surgery programs in Cameroon.Addressing these priorities will be critical to improving access to timely surgical care and reducing preventable mortality from rheumatic heart disease. 展开更多
关键词 Rheumatic Heart Disease Valvular Surgery Cardiac Surgery Cameroon Sub-Saharan Africa Universal Health Coverage
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Metabolic Surgery: Concepts and New Classification
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作者 Paulo Reis Rizzo Esselin de Melo Victor Ramos Mussa Dib +34 位作者 Carlos Augusto Scussel Madalosso Chetan Parmar Omar Ghanem Miguel Ángel Carbajo Ricardo Zorron Amador García Ruiz de Gordejuela Caio Gustavo Gaspar de Aquino Luiz Alfredo Vieira d’Almeida Luciano Antozzi Rui Ribeiro Halit Eren Taskin Jorge Bravo López Christine Stier Patrick Noel José Sergio Verboonen Sotelo Laurent Abram Layani Ramon Vilallonga Puy Elinton Adami Chaim Helmuth Billy Carlos Eduardo Domene Paula Volpe Nilton Tokio Kawahara Augusto Cláudio de Almeida Tinoco Antelmo Sasso Fin Hiroji Okano Júnior Nicholas Tavares Kruel Giorgio Alfredo Pedroso Baretta Diogo Swain Kfouri Anna Carolina Hoff Fernando Reis Esselin Melo Thonya Cruz Braga Clayton Alencar Moreira Luis Poggi Almino Cardoso Ramos Antonio Torres 《Surgical Science》 2025年第2期87-109,共23页
Bariatric and metabolic surgeries have gained extensive popularity and trust due to their documented efficacy and safety in managing not only obesity but also associated comorbidities such as diabetes mellitus, hypert... Bariatric and metabolic surgeries have gained extensive popularity and trust due to their documented efficacy and safety in managing not only obesity but also associated comorbidities such as diabetes mellitus, hypertension, dyslipidemia, sleep apnea, and joint pain. Traditionally, bariatric surgeries have been categorized into hypoabsorptive, restrictive, or hybrid approaches. However, these classifications inadequately reflect the complex anatomical and physiological alterations associated with modern surgical methodologies. This paper explores the evolution of metabolic surgeries, emphasizing the integration of physiological concepts into classic procedures to provide more tailored and effective treatment options for obesity and its comorbidities. Finally, the proposal for a new classification based on current metabolic concepts will facilitate communication among patients, doctors, and healthcare professionals. Additionally, it will enable a more didactic and standardized approach to data collection for conducting studies and publications. 展开更多
关键词 Metabolic Surgery Bariatric Surgery OBESITY Physiological Concepts Gastrointestinal Procedures Transit Bipartition Long Common Channel Metabolically Functional Stomach Wide Anastomosis
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