In the very beginning,the Computer Laboratory of the University of Cambridge was founded to provide computing service for different disciplines across the university.As computer science developed as a discipline in it...In the very beginning,the Computer Laboratory of the University of Cambridge was founded to provide computing service for different disciplines across the university.As computer science developed as a discipline in its own right,boundaries necessarily arose between it and other disciplines,in a way that is now often detrimental to progress.Therefore,it is necessary to reinvigorate the relationship between computer science and other academic disciplines and celebrate exploration and creativity in research.To do this,the structures of the academic department have to act as supporting scaffolding rather than barriers.Some examples are given that show the efforts being made at the University of Cambridge to approach this problem.展开更多
The technology of remote transaction mirror image is a feasible, low-investment and well-effect disaster backup scheme in finance business system. The basic idea, construction, working principles and characteristic of...The technology of remote transaction mirror image is a feasible, low-investment and well-effect disaster backup scheme in finance business system. The basic idea, construction, working principles and characteristic of remote transaction mirror image are presented in this paper. We analyze and compare similarities and differences among this disaster backup scheme and others usually used. The technology of remote transaction mirror image have the advantages such as less requiring of software and hardware system platform, low-investment, being able to control and restore lost data, insuring the data consistency and integrity.展开更多
The present study utilized motor imaginary-based brain-computer interface technology combined with rehabilitation training in 20 stroke patients. Results from the Berg Balance Scale and the Holden Walking Classificati...The present study utilized motor imaginary-based brain-computer interface technology combined with rehabilitation training in 20 stroke patients. Results from the Berg Balance Scale and the Holden Walking Classification were significantly greater at 4 weeks after treatment (P 〈 0.01), which suggested that motor imaginary-based brain-computer interface technology improved balance and walking in stroke patients.展开更多
With the rapid development of wireless transmission technologies and the proliferation of mobile terminals, the mobile Internet has experienced exponential growth in recent years. However, at the same time, it is also...With the rapid development of wireless transmission technologies and the proliferation of mobile terminals, the mobile Internet has experienced exponential growth in recent years. However, at the same time, it is also facing more challenges, particularly regarding bandwidth, address space, security, mobility, and energy. In this article, we analyse the five abovementioned challenges and then survey related technology trends. We also describe the progress of architecture research aimed at the future mobile Internet. We reach the conclusion that a single technology cannot solve all the problems of mobile Internet, and future research should focus more on how to make architectures and technologies work together more effectively.展开更多
At the panel session of the 3rd Global Forum on the Development of Computer Science,attendees had an opportunity to deliberate recent issues affecting computer science departments as a result of the recent growth in t...At the panel session of the 3rd Global Forum on the Development of Computer Science,attendees had an opportunity to deliberate recent issues affecting computer science departments as a result of the recent growth in the field.6 heads of university computer science departments participated in the discussions,including the moderator,Professor Andrew Yao.The first issue was how universities are managing the growing number of applicants in addition to swelling class sizes.Several approaches were suggested,including increasing faculty hiring,implementing scalable teaching tools,and working closer with other departments through degree programs that integrate computer science with other fields.The second issue was about the position and role of computer science within broader science.Participants generally agreed that all fields are increasingly relying on computer science techniques,and that effectively disseminating these techniques to others is a key to unlocking broader scientific progress.展开更多
Spark performs excellently in large-scale data-parallel computing and iterative processing.However,with the increase in data size and program complexity,the default scheduling strategy has difficultymeeting the demand...Spark performs excellently in large-scale data-parallel computing and iterative processing.However,with the increase in data size and program complexity,the default scheduling strategy has difficultymeeting the demands of resource utilization and performance optimization.Scheduling strategy optimization,as a key direction for improving Spark’s execution efficiency,has attracted widespread attention.This paper first introduces the basic theories of Spark,compares several default scheduling strategies,and discusses common scheduling performance evaluation indicators and factors affecting scheduling efficiency.Subsequently,existing scheduling optimization schemes are summarized based on three scheduling modes:load characteristics,cluster characteristics,and matching of both,and representative algorithms are analyzed in terms of performance indicators and applicable scenarios,comparing the advantages and disadvantages of different scheduling modes.The article also explores in detail the integration of Spark scheduling strategies with specific application scenarios and the challenges in production environments.Finally,the limitations of the existing schemes are analyzed,and prospects are envisioned.展开更多
The utilization of millimeter-wave frequencies and cognitive radio(CR)are promising ways to increase the spectral efficiency of wireless communication systems.However,conventional CR spectrum sensing techniques entail...The utilization of millimeter-wave frequencies and cognitive radio(CR)are promising ways to increase the spectral efficiency of wireless communication systems.However,conventional CR spectrum sensing techniques entail sampling the received signal at a Nyquist rate,and they are not viable for wideband signals due to their high cost.This paper expounds on how sub-Nyquist sampling in conjunction with deep learning can be leveraged to remove this limitation.To this end,we propose a multi-task learning(MTL)framework using convolutional neural networks for the joint inference of the underlying narrowband signal number,their modulation scheme,and their location in a wideband spectrum.We demonstrate the effectiveness of the proposed framework for real-world millimeter-wave wideband signals collected by physical devices,exhibiting a 91.7% accuracy in the joint inference task when considering up to two narrowband signals over a wideband spectrum.Ultimately,the proposed data-driven approach enables on-the-fly wideband spectrum sensing,combining accuracy,and computational efficiency,which are indispensable for CR and opportunistic networking.展开更多
Recent advances in artificial intelligence and the availability of large-scale benchmarks have made deepfake video generation and manipulation easier.Therefore,developing reliable and robust deepfake video detection m...Recent advances in artificial intelligence and the availability of large-scale benchmarks have made deepfake video generation and manipulation easier.Therefore,developing reliable and robust deepfake video detection mechanisms is paramount.This research introduces a novel real-time deepfake video detection framework by analyzing gaze and blink patterns,addressing the spatial-temporal challenges unique to gaze and blink anomalies using the TimeSformer and hybrid Transformer-CNN models.The TimeSformer architecture leverages spatial-temporal attention mechanisms to capture fine-grained blinking intervals and gaze direction anomalies.Compared to state-of-the-art traditional convolutional models like MesoNet and EfficientNet,which primarily focus on global facial features,our approach emphasizes localized eye-region analysis,significantly enhancing detection accuracy.We evaluate our framework on four standard datasets:FaceForensics,CelebDF-V2,DFDC,and FakeAVCeleb.The proposed framework results reveal higher accuracy,with the TimeSformer model achieving accuracies of 97.5%,96.3%,95.8%,and 97.1%,and with the hybrid Transformer-CNN model demonstrating accuracies of 92.8%,91.5%,90.9%,and 93.2%,on FaceForensics,CelebDF-V2,DFDC,and FakeAVCeleb datasets,respectively,showing robustness in distinguishing manipulated from authentic videos.Our research provides a robust state-of-the-art framework for real-time deepfake video detection.This novel study significantly contributes to video forensics,presenting scalable and accurate real-world application solutions.展开更多
BACKGROUND Although thymopoietin(TMPO)has been elucidated to be overexpressed in cancers,its underlying mechanisms are not yet fully understood.AIM To investigate the expression and clinical significance of TMPO in pa...BACKGROUND Although thymopoietin(TMPO)has been elucidated to be overexpressed in cancers,its underlying mechanisms are not yet fully understood.AIM To investigate the expression and clinical significance of TMPO in papillary thyroid carcinoma(PTC).METHODS Databases such as Gene Expression Omnibus,The Cancer Genome Atlas Proand summary receiver operating characteristic curves were plotted to evaluate diagnostic performance.A Gene Set Enrichment Analysis enrichment analysis was conducted to identify TMPO-related signaling pathways.A protein interaction network was constructed to identify hub genes.The impact of TMPO on PTC cell proliferation and the effects of its knockout were analyzed using clustered regularly interspaced short palindromic repeats(CRISPR)knockout screening and the Cancer Cell Line Encyclopedia database.RESULTS The TMPO protein was significantly overexpressed in PTC tissues,primarily localized in the cytoplasm and nuclear membrane.The mRNA level analysis showed mild overexpression of TMPO in PTC tissues,with a certain discriminatory value(area under the curve=0.66).TMPO may promote cancer through involvement in cell adhesion,focal adhesion,leukocyte migration,and multiple cancer-related signaling pathways.Additionally,CRISPR gene knockout experiments confirmed that TMPO knockout significantly inhibited the proliferation of PTC cell lines,indicating its important role in tumor growth.CONCLUSION TMPO is overexpressed in PTC and may serve as a therapeutic target and molecular biomarker for PTC.展开更多
BACKGROUND Laryngeal squamous cell carcinoma(LSCC)is a prevalent head and neck malignancy with suboptimal survival rates due to late detection and therapeutic resistance.AIM To investigate chaperonin-containing TCP1 s...BACKGROUND Laryngeal squamous cell carcinoma(LSCC)is a prevalent head and neck malignancy with suboptimal survival rates due to late detection and therapeutic resistance.AIM To investigate chaperonin-containing TCP1 subunit 3(CCT3)expression and its clinical implications,and its effects on LSCC cell growth.METHODS Systematic data on CCT3 mRNA expression were collected from biomedical databases,and integrated further based on the standardized mean difference and the summary receiver operating characteristic curve.Single-cell RNA-seq data were mined to validate the expression level of CCT3 mRNA.In-house immunohistochemistry was performed to explore the CCT3 protein levels of clinical LSCC samples and their relationship with clinical parameters.The growth function of LSCC cell was analyzed using CRISPR knockout screening.CCT3-related signaling pathway analyses were conducted using gene set enrichment analysis.Protein-protein interaction network construction was performed to identify hub genes.RESULTS CCT3 mRNA was significantly overexpressed in 269 LSCC tissues cases across multiple independent datasets(standardized mean difference=32,area under the curve=0.93);At the translational level,the in-house immunohistochemical analysis further demonstrated the consistent upregulation of CCT3 protein in 88 cases of LSCC samples(58 non-LSCC samples vs 30 LSCC samples,P=1.4e^(-14)).Analysis of clinical parameters showed no significant differences among subgroup.Functional characterization with clustered regularly interspaced short palindromic repeats--mediated gene knockout revealed that depletion of CCT3 potently suppressed LSCC cell viability in vitro.Gene set enrichment analysis indicated that CCT3 was markedly associated with several key oncogenic pathways,including extracellular matrix receptor interaction and cell cycle regulation pathways.CONCLUSION CCT3 upregulation in LSCC may influence cellular growth by regulating related pathways,indicating its potential as a biomarker and therapeutic target for LSCC.展开更多
Cotton fibers elongate rapidly after initiation of elongation, eventually leading to the deposit of a large amount of cellulose. To reveal features of cotton fiber cells at the fast elongation and the secondary cell w...Cotton fibers elongate rapidly after initiation of elongation, eventually leading to the deposit of a large amount of cellulose. To reveal features of cotton fiber cells at the fast elongation and the secondary cell wall synthesis stages, we compared the respective transcriptomes and metabolite profiles. Comparative analysis of transcriptomes by cDNA array identified 633 genes that were differentially regulated during fiber development. Principal component analysis (PCA) using expressed genes as variables divided fiber samples into four groups, which are diagnostic of developmental stages. Similar grouping results are also found if we use non-polar or polar metabolites as variables for PCA of developing fibers. Auxin signaling, wall-loosening and lipid metabolism are highly active during fiber elongation, whereas cellulose biosynthesis is predominant and many other metabolic pathways are downregulated at the secondary cell wall synthesis stage. Transcript and metabolite profiles and enzyme activities are consistent in demonstrating a specialization process of cotton fiber development toward cellulose synthesis. These data demonstrate that cotton fiber cell at a certain stage has its own unique feature, and developmental stages of cotton fiber cells can be distinguished by their transcript and metabolite profiles. During the secondary cell wall synthesis stage, metabolic pathways are streamed into cellulose synthesis.展开更多
We present a robust connected-component (CC) based method for automatic detection and segmentation of text in real-scene images. This technique can be applied in robot vision, sign recognition, meeting processing and ...We present a robust connected-component (CC) based method for automatic detection and segmentation of text in real-scene images. This technique can be applied in robot vision, sign recognition, meeting processing and video indexing. First, a Non-Linear Niblack method (NLNiblack) is proposed to decompose the image into candidate CCs. Then, all these CCs are fed into a cascade of classifiers trained by Adaboost algorithm. Each classifier in the cascade responds to one feature of the CC. Proposed here are 12 novel features which are insensitive to noise, scale, text orientation and text language. The classifier cascade allows non-text CCs of the image to be rapidly discarded while more computation is spent on promising text-like CCs. The CCs passing through the cascade are considered as text components and are used to form the segmentation result. A prototype system was built, with experimental results proving the effectiveness and efficiency of the proposed method.展开更多
Microblogs currently play an important role in social communication. Hot topics currently being tweeted can quickly become popular within a very short time as a result of retweeting. Gaining an understanding of the re...Microblogs currently play an important role in social communication. Hot topics currently being tweeted can quickly become popular within a very short time as a result of retweeting. Gaining an understanding of the retweeting behavior is desirable for a number of tasks such as topic detection, personalized message recommendation, and fake information monitoring and prevention. Interestingly, the propagation of tweets bears some similarity to the spread of infectious diseases. We present a method to model the tweets' spread behavior in microblogs based on the classic Susceptible-Infectious-Susceptible (SIS) epidemic model that was developed in the medical field for the spread of infectious diseases. On the basis of this model, future retweeting trends can be predicted. Our experiments on data obtained from the Chinese micro-blogging website Sina Weibo show that the proposed model has lower predictive error compared to the four commonly used prediction methods.展开更多
Recent advances in wireless communication technologies and auto-mobile industry have triggered a significant research interest in the field of vehicular ad-hoc networks (VANETs) over the past few years. A vehicular ...Recent advances in wireless communication technologies and auto-mobile industry have triggered a significant research interest in the field of vehicular ad-hoc networks (VANETs) over the past few years. A vehicular network consists of vehicle-to-vehicle (V2V) and vehicle-to-infrastructure (V2I) communications supported by wireless access technologies such as IEEE 802.11p. This innovation in wireless communication has been envisaged to improve road safety and motor traffic efficiency in near future through the development of intelligent transportation system (ITS). Hence, governments, auto-mobile industries and academia are heavily partnering through several ongoing research projects to establish standards for VANETs. The typical set of VANET application areas, such as vehicle collision warning and traffic information dissemination have made VANET an interesting field of mobile wireless communication. This paper provides an overview on current research state, challenges, potentials of VANETs as well as the ways forward to achieving the long awaited ITS.展开更多
The nesting problem involves arranging pieces on a plate to maximize use of material. A new scheme for 2D ir- regular-shaped nesting problem is proposed. The new scheme is based on the NFP (No Fit Polygon) algorithm a...The nesting problem involves arranging pieces on a plate to maximize use of material. A new scheme for 2D ir- regular-shaped nesting problem is proposed. The new scheme is based on the NFP (No Fit Polygon) algorithm and a new placement principle for pieces. The novel placement principle is to place a piece to the position with lowest gravity center based on NFP. In addition, genetic algorithm (GA) is adopted to find an efficient nesting sequence. The proposed scheme can deal with pieces with arbitrary rotation and containing region with holes, and achieves competitive results in experiment on benchmark datasets.展开更多
The basic function of the Internet is to delivery data(what) to serve the needs of all applications. IP names the attachment points(where) to facilitate ubiquitous interconnectivity as the current way to deliver data....The basic function of the Internet is to delivery data(what) to serve the needs of all applications. IP names the attachment points(where) to facilitate ubiquitous interconnectivity as the current way to deliver data. The fundamental mismatch between data delivery and naming attachment points leads to a lot of challenges, e.g., mapping from data name to IP address, handling dynamics of underlying topology, scaling up the data distribution, and securing communication, etc. Informationcentric networking(ICN) is proposed to shift the focus of communication paradigm from where to what, by making the named data the first-class citizen in the network, The basic consensus of ICN is to name the data independent from its container(space dimension) and session(time dimension), which breaks the limitation of point-to-point IP semantic. It scales up data distribution by utilizing available resources, and facilitates communication to fit diverse connectivity and heterogeneous networks. However, there are only a few consensuses on the detailed design of ICN, and quite a few different ICN architectures are proposed. This paper reveals the rationales of ICN from the perspective of the Internet evolution, surveys different design choices, and discusses on two debatable topics in ICN, i.e.,self-certifying versus hierarchical names, and edge versus pervasive caching. We hope this survey helps clarify some mis-understandings on ICN and achieve more consensuses.展开更多
The Ecological-living-productive land(ELPL)classification system was proposed in an effort to steer China's land pattern to an ecological-centered path,with the development model shifting from a single function in...The Ecological-living-productive land(ELPL)classification system was proposed in an effort to steer China's land pattern to an ecological-centered path,with the development model shifting from a single function into more integrated multifunction land use.The focus is coordinating the man-land contradictions and developing an intensive,efficient and sustainable land use policy in an increasingly tense relationship between humans and nature.Driven by socioeconomic change and rapid population growth,many cities are undergoing urban sprawl,which involves the consumption of cropland and ecological land and threatens the ecological balance.This paper aims to quantitatively analyze the critical effects of ELPL changes on eco-environmental quality according to land use classification based on leading function of ecology,living and production from 1990 to 2015 with a case study of Xining City.Also,four future land use scenarios were simulated for 2030 using the Future Land Use Simulation(FLUS)model that couples human and natural effects.Our results show a decrease in productive land(PL)and an increase in ecological land(EL)and living land(LL)in Xining City.Forestry ecological land(FEL)covered the top largest proportion;agriculture productive land(APL)showed the greatest reduction and urban and rural living land(U-RLL)presented a dramatic increase.The eco-environmental quality improved in 1990-2010,mainly affected by the conversion of APL to FEL and GEL.However,the encroachment of U-RLL into APL,other ecological land(OEL)and FEL was the main contributor to the decline in eco-environmental quality in 2010-2015 as well as the primary reason for the increase area of lower-quality.The Harmonious Development(HD)-Scenario,characterized by a rational allocation of LL and PL and a better eco-environment,would have implications for planning and monitoring future management of ELPL,and may represent a valuable reference for local policy-makers.展开更多
The Lyman-alpha Solar Telescope(LST)is one of the three payloads onboard the Advanced Space-based Solar Observatory(ASO-S)mission.It aims at imaging the Sun from the disk center up to 2.5 R⊙targeting solar eruptions,...The Lyman-alpha Solar Telescope(LST)is one of the three payloads onboard the Advanced Space-based Solar Observatory(ASO-S)mission.It aims at imaging the Sun from the disk center up to 2.5 R⊙targeting solar eruptions,particularly coronal mass ejections(CMEs),solar flares,prominences/filaments and related phenomena,as well as the fast and slow solar wind.The most prominent speciality of LST is the simultaneous observation of the solar atmosphere in both Lyαand white light(WL)with high temporospatial resolution both on the solar disk and the inner corona.New observations in the Lyαline together with traditional WL observations will provide us with many new insights into solar eruptions and solar wind.LST consists of a Solar Corona Imager(SCI)with a field of view(FOV)of 1.1–2.5 R⊙,a Solar Disk Imager(SDI)and a full-disk White-light Solar Telescope(WST)with an identical FOV up to 1.2 R⊙.SCI has a dual waveband in Lyα(121.6±10 nm)and in WL(700±40 nm),while SDI works in the Lyαwaveband of 121.6±7.5 nm and WST works in the violet narrow-band continuum of 360±2.0 nm.To produce high quality science data,careful ground and in-flight calibrations are required.We present our methods for different calibrations including dark field correction,flat field correction,radiometry,instrumental polarization and optical geometry.Based on the data calibration,definitions of the data levels and processing procedures for the defined levels from raw data are described.Plasma physical diagnostics offer key ingredients to understand ejecta and plasma flows in the inner corona,as well as different features on the solar disk including flares,filaments,etc.Therefore,we are making efforts to develop various tools to detect the different features observed by LST,and then to derive their physical parameters,for example,the electron density and temperature of CMEs,the outflow velocity of the solar wind,and the hydrogen density and mass flows of prominences.Coordinated observations and data analyses with the coronagraphs onboard Solar Orbiter,PROBA-3,and Aditya are also briefly discussed.展开更多
With the advance of smart material science,robotics is evolving from rigid robots to soft robots.Compared to rigid robots,soft robots can safely interact with the environment,easily navigate in unstructured fields,and...With the advance of smart material science,robotics is evolving from rigid robots to soft robots.Compared to rigid robots,soft robots can safely interact with the environment,easily navigate in unstructured fields,and be minimized to operate in narrow spaces,owning to the new actuation and sensing technologies developed by the smart materials.In the review,different actuation and sensing technologies based on different smart materials are analyzed and summarized.According to the driving or feedback signals,actuators are categorized into electrically responsive actuators,thermally responsive actuators,magnetically responsive actuators,and photoresponsive actuators;sensors are categorized into resistive sensors,capacitive sensors,magnetic sensors,and optical waveguide sensors.After introducing the principle and several robotic prototypes of some typical materials in each category of the actuators and sensors.The advantages and disadvantages of the actuators and sensors are compared based on the categories,and their potential applications in robotics are also presented.展开更多
A great deal of ocean sensor observation data exists, for a wide range of marine disciplines, derived from in situ and remote observing platforms, in real-time, near-real-time and delayed mode. Ocean monitoring is rou...A great deal of ocean sensor observation data exists, for a wide range of marine disciplines, derived from in situ and remote observing platforms, in real-time, near-real-time and delayed mode. Ocean monitoring is routinely completed using sensors and instruments. Standardization is the key requirement for exchanging information about ocean sensors and sensor data and for comparing and combining information from different sensor networks. One or more sensors are often physically integrated into a single ocean ‘instrument' device, which often brings in many challenges related to diverse sensor data formats, parameters units, different spatiotemporal resolution, application domains, data quality and sensors protocols. To face these challenges requires the standardization efforts aiming at facilitating the so-called Sensor Web, which making it easy to provide public access to sensor data and metadata information. In this paper, a Marine Sensor Web, based on SOA and EDA and integrating the MBARI's PUCK protocol, IEEE 1451 and OGC SWE 2.0, is illustrated with a five-layer architecture. The Web Service layer and Event Process layer are illustrated in detail with an actual example. The demo study has demonstrated that a standard-based system can be built to access sensors and marine instruments distributed globally using common Web browsers for monitoring the environment and oceanic conditions besides marine sensor data on the Web, this framework of Marine Sensor Web can also play an important role in many other domains' information integration.展开更多
文摘In the very beginning,the Computer Laboratory of the University of Cambridge was founded to provide computing service for different disciplines across the university.As computer science developed as a discipline in its own right,boundaries necessarily arose between it and other disciplines,in a way that is now often detrimental to progress.Therefore,it is necessary to reinvigorate the relationship between computer science and other academic disciplines and celebrate exploration and creativity in research.To do this,the structures of the academic department have to act as supporting scaffolding rather than barriers.Some examples are given that show the efforts being made at the University of Cambridge to approach this problem.
基金This work was supported by"Shu Guang"project of Shanghai Municipal Education Commission and Shanghai Education Development Foundation (No.2002SG53) and was also supported by Science and Technology Foundation of Shanghai Higher Education (No.CL200222).
文摘The technology of remote transaction mirror image is a feasible, low-investment and well-effect disaster backup scheme in finance business system. The basic idea, construction, working principles and characteristic of remote transaction mirror image are presented in this paper. We analyze and compare similarities and differences among this disaster backup scheme and others usually used. The technology of remote transaction mirror image have the advantages such as less requiring of software and hardware system platform, low-investment, being able to control and restore lost data, insuring the data consistency and integrity.
基金the National Natural Science Foundation of China,No.60970062the Shanghai Pujiang Program,No.09PJ1410200
文摘The present study utilized motor imaginary-based brain-computer interface technology combined with rehabilitation training in 20 stroke patients. Results from the Berg Balance Scale and the Holden Walking Classification were significantly greater at 4 weeks after treatment (P 〈 0.01), which suggested that motor imaginary-based brain-computer interface technology improved balance and walking in stroke patients.
基金supportedin part by Sub-project "Mobile Internet Architecture and Key Technology Research" of National Core Electronic Devices,High-end Generic Chips and Basic Software (CHBS) Project "Development Strategy and Planning ofMobile Internet System Hardware and Software Technology and Service" under Grant No.2012ZX01039003Sub-project "IPv6 Application and Demonstration of Mobile Internet inCampus Environment" of National Sci-Tech Major Special Item Project "IPv6 Applicationand Demonstration of Mobile Internet" under Grant No. 2012ZX03002015-003A New Network Architecture:Address Driven Network Architecture and Technology Research and Development under Grant No. CNGI-12-03-001
文摘With the rapid development of wireless transmission technologies and the proliferation of mobile terminals, the mobile Internet has experienced exponential growth in recent years. However, at the same time, it is also facing more challenges, particularly regarding bandwidth, address space, security, mobility, and energy. In this article, we analyse the five abovementioned challenges and then survey related technology trends. We also describe the progress of architecture research aimed at the future mobile Internet. We reach the conclusion that a single technology cannot solve all the problems of mobile Internet, and future research should focus more on how to make architectures and technologies work together more effectively.
文摘At the panel session of the 3rd Global Forum on the Development of Computer Science,attendees had an opportunity to deliberate recent issues affecting computer science departments as a result of the recent growth in the field.6 heads of university computer science departments participated in the discussions,including the moderator,Professor Andrew Yao.The first issue was how universities are managing the growing number of applicants in addition to swelling class sizes.Several approaches were suggested,including increasing faculty hiring,implementing scalable teaching tools,and working closer with other departments through degree programs that integrate computer science with other fields.The second issue was about the position and role of computer science within broader science.Participants generally agreed that all fields are increasingly relying on computer science techniques,and that effectively disseminating these techniques to others is a key to unlocking broader scientific progress.
基金supported in part by the Key Research and Development Program of Shaanxi under Grant 2023-ZDLGY-34.
文摘Spark performs excellently in large-scale data-parallel computing and iterative processing.However,with the increase in data size and program complexity,the default scheduling strategy has difficultymeeting the demands of resource utilization and performance optimization.Scheduling strategy optimization,as a key direction for improving Spark’s execution efficiency,has attracted widespread attention.This paper first introduces the basic theories of Spark,compares several default scheduling strategies,and discusses common scheduling performance evaluation indicators and factors affecting scheduling efficiency.Subsequently,existing scheduling optimization schemes are summarized based on three scheduling modes:load characteristics,cluster characteristics,and matching of both,and representative algorithms are analyzed in terms of performance indicators and applicable scenarios,comparing the advantages and disadvantages of different scheduling modes.The article also explores in detail the integration of Spark scheduling strategies with specific application scenarios and the challenges in production environments.Finally,the limitations of the existing schemes are analyzed,and prospects are envisioned.
文摘The utilization of millimeter-wave frequencies and cognitive radio(CR)are promising ways to increase the spectral efficiency of wireless communication systems.However,conventional CR spectrum sensing techniques entail sampling the received signal at a Nyquist rate,and they are not viable for wideband signals due to their high cost.This paper expounds on how sub-Nyquist sampling in conjunction with deep learning can be leveraged to remove this limitation.To this end,we propose a multi-task learning(MTL)framework using convolutional neural networks for the joint inference of the underlying narrowband signal number,their modulation scheme,and their location in a wideband spectrum.We demonstrate the effectiveness of the proposed framework for real-world millimeter-wave wideband signals collected by physical devices,exhibiting a 91.7% accuracy in the joint inference task when considering up to two narrowband signals over a wideband spectrum.Ultimately,the proposed data-driven approach enables on-the-fly wideband spectrum sensing,combining accuracy,and computational efficiency,which are indispensable for CR and opportunistic networking.
文摘Recent advances in artificial intelligence and the availability of large-scale benchmarks have made deepfake video generation and manipulation easier.Therefore,developing reliable and robust deepfake video detection mechanisms is paramount.This research introduces a novel real-time deepfake video detection framework by analyzing gaze and blink patterns,addressing the spatial-temporal challenges unique to gaze and blink anomalies using the TimeSformer and hybrid Transformer-CNN models.The TimeSformer architecture leverages spatial-temporal attention mechanisms to capture fine-grained blinking intervals and gaze direction anomalies.Compared to state-of-the-art traditional convolutional models like MesoNet and EfficientNet,which primarily focus on global facial features,our approach emphasizes localized eye-region analysis,significantly enhancing detection accuracy.We evaluate our framework on four standard datasets:FaceForensics,CelebDF-V2,DFDC,and FakeAVCeleb.The proposed framework results reveal higher accuracy,with the TimeSformer model achieving accuracies of 97.5%,96.3%,95.8%,and 97.1%,and with the hybrid Transformer-CNN model demonstrating accuracies of 92.8%,91.5%,90.9%,and 93.2%,on FaceForensics,CelebDF-V2,DFDC,and FakeAVCeleb datasets,respectively,showing robustness in distinguishing manipulated from authentic videos.Our research provides a robust state-of-the-art framework for real-time deepfake video detection.This novel study significantly contributes to video forensics,presenting scalable and accurate real-world application solutions.
基金Supported by Guangxi Zhuang Autonomous Region Health Commission Scientific Research Project,No.Z-A20220521Guangxi Higher Education Undergraduate Teaching Reform Project,No.2022JGA147The National College Students’Innovation and Entrepreneurship Training Program,No.202310598042.
文摘BACKGROUND Although thymopoietin(TMPO)has been elucidated to be overexpressed in cancers,its underlying mechanisms are not yet fully understood.AIM To investigate the expression and clinical significance of TMPO in papillary thyroid carcinoma(PTC).METHODS Databases such as Gene Expression Omnibus,The Cancer Genome Atlas Proand summary receiver operating characteristic curves were plotted to evaluate diagnostic performance.A Gene Set Enrichment Analysis enrichment analysis was conducted to identify TMPO-related signaling pathways.A protein interaction network was constructed to identify hub genes.The impact of TMPO on PTC cell proliferation and the effects of its knockout were analyzed using clustered regularly interspaced short palindromic repeats(CRISPR)knockout screening and the Cancer Cell Line Encyclopedia database.RESULTS The TMPO protein was significantly overexpressed in PTC tissues,primarily localized in the cytoplasm and nuclear membrane.The mRNA level analysis showed mild overexpression of TMPO in PTC tissues,with a certain discriminatory value(area under the curve=0.66).TMPO may promote cancer through involvement in cell adhesion,focal adhesion,leukocyte migration,and multiple cancer-related signaling pathways.Additionally,CRISPR gene knockout experiments confirmed that TMPO knockout significantly inhibited the proliferation of PTC cell lines,indicating its important role in tumor growth.CONCLUSION TMPO is overexpressed in PTC and may serve as a therapeutic target and molecular biomarker for PTC.
基金Supported by the National Natural Science Foundation of China,No.82160213 and No.U22A2022the Guangxi Natural Science Foundation,No.2023GXNSFAA026029,No.2024GXNSFBA010059,and No.2024GXNSFAA010079。
文摘BACKGROUND Laryngeal squamous cell carcinoma(LSCC)is a prevalent head and neck malignancy with suboptimal survival rates due to late detection and therapeutic resistance.AIM To investigate chaperonin-containing TCP1 subunit 3(CCT3)expression and its clinical implications,and its effects on LSCC cell growth.METHODS Systematic data on CCT3 mRNA expression were collected from biomedical databases,and integrated further based on the standardized mean difference and the summary receiver operating characteristic curve.Single-cell RNA-seq data were mined to validate the expression level of CCT3 mRNA.In-house immunohistochemistry was performed to explore the CCT3 protein levels of clinical LSCC samples and their relationship with clinical parameters.The growth function of LSCC cell was analyzed using CRISPR knockout screening.CCT3-related signaling pathway analyses were conducted using gene set enrichment analysis.Protein-protein interaction network construction was performed to identify hub genes.RESULTS CCT3 mRNA was significantly overexpressed in 269 LSCC tissues cases across multiple independent datasets(standardized mean difference=32,area under the curve=0.93);At the translational level,the in-house immunohistochemical analysis further demonstrated the consistent upregulation of CCT3 protein in 88 cases of LSCC samples(58 non-LSCC samples vs 30 LSCC samples,P=1.4e^(-14)).Analysis of clinical parameters showed no significant differences among subgroup.Functional characterization with clustered regularly interspaced short palindromic repeats--mediated gene knockout revealed that depletion of CCT3 potently suppressed LSCC cell viability in vitro.Gene set enrichment analysis indicated that CCT3 was markedly associated with several key oncogenic pathways,including extracellular matrix receptor interaction and cell cycle regulation pathways.CONCLUSION CCT3 upregulation in LSCC may influence cellular growth by regulating related pathways,indicating its potential as a biomarker and therapeutic target for LSCC.
文摘Cotton fibers elongate rapidly after initiation of elongation, eventually leading to the deposit of a large amount of cellulose. To reveal features of cotton fiber cells at the fast elongation and the secondary cell wall synthesis stages, we compared the respective transcriptomes and metabolite profiles. Comparative analysis of transcriptomes by cDNA array identified 633 genes that were differentially regulated during fiber development. Principal component analysis (PCA) using expressed genes as variables divided fiber samples into four groups, which are diagnostic of developmental stages. Similar grouping results are also found if we use non-polar or polar metabolites as variables for PCA of developing fibers. Auxin signaling, wall-loosening and lipid metabolism are highly active during fiber elongation, whereas cellulose biosynthesis is predominant and many other metabolic pathways are downregulated at the secondary cell wall synthesis stage. Transcript and metabolite profiles and enzyme activities are consistent in demonstrating a specialization process of cotton fiber development toward cellulose synthesis. These data demonstrate that cotton fiber cell at a certain stage has its own unique feature, and developmental stages of cotton fiber cells can be distinguished by their transcript and metabolite profiles. During the secondary cell wall synthesis stage, metabolic pathways are streamed into cellulose synthesis.
文摘We present a robust connected-component (CC) based method for automatic detection and segmentation of text in real-scene images. This technique can be applied in robot vision, sign recognition, meeting processing and video indexing. First, a Non-Linear Niblack method (NLNiblack) is proposed to decompose the image into candidate CCs. Then, all these CCs are fed into a cascade of classifiers trained by Adaboost algorithm. Each classifier in the cascade responds to one feature of the CC. Proposed here are 12 novel features which are insensitive to noise, scale, text orientation and text language. The classifier cascade allows non-text CCs of the image to be rapidly discarded while more computation is spent on promising text-like CCs. The CCs passing through the cascade are considered as text components and are used to form the segmentation result. A prototype system was built, with experimental results proving the effectiveness and efficiency of the proposed method.
基金supported by National Natural Science Foundation of China under Grants No. 60773156, No. 61073004Chinese Major State Basic Research Development 973 Program under Grant No. 2011CB302203-2Important National Science &Technology Specific Program under Grant No. 2011ZX01042001-002-2
文摘Microblogs currently play an important role in social communication. Hot topics currently being tweeted can quickly become popular within a very short time as a result of retweeting. Gaining an understanding of the retweeting behavior is desirable for a number of tasks such as topic detection, personalized message recommendation, and fake information monitoring and prevention. Interestingly, the propagation of tweets bears some similarity to the spread of infectious diseases. We present a method to model the tweets' spread behavior in microblogs based on the classic Susceptible-Infectious-Susceptible (SIS) epidemic model that was developed in the medical field for the spread of infectious diseases. On the basis of this model, future retweeting trends can be predicted. Our experiments on data obtained from the Chinese micro-blogging website Sina Weibo show that the proposed model has lower predictive error compared to the four commonly used prediction methods.
基金supported by a Grant-in-Aid for Scientific Research from Ebonyi State Government(EBSG)(No.EBSG/SSB/PS/VII/105)
文摘Recent advances in wireless communication technologies and auto-mobile industry have triggered a significant research interest in the field of vehicular ad-hoc networks (VANETs) over the past few years. A vehicular network consists of vehicle-to-vehicle (V2V) and vehicle-to-infrastructure (V2I) communications supported by wireless access technologies such as IEEE 802.11p. This innovation in wireless communication has been envisaged to improve road safety and motor traffic efficiency in near future through the development of intelligent transportation system (ITS). Hence, governments, auto-mobile industries and academia are heavily partnering through several ongoing research projects to establish standards for VANETs. The typical set of VANET application areas, such as vehicle collision warning and traffic information dissemination have made VANET an interesting field of mobile wireless communication. This paper provides an overview on current research state, challenges, potentials of VANETs as well as the ways forward to achieving the long awaited ITS.
基金Project (No. 60573146) supported by the National Natural ScienceFoundation of China
文摘The nesting problem involves arranging pieces on a plate to maximize use of material. A new scheme for 2D ir- regular-shaped nesting problem is proposed. The new scheme is based on the NFP (No Fit Polygon) algorithm and a new placement principle for pieces. The novel placement principle is to place a piece to the position with lowest gravity center based on NFP. In addition, genetic algorithm (GA) is adopted to find an efficient nesting sequence. The proposed scheme can deal with pieces with arbitrary rotation and containing region with holes, and achieves competitive results in experiment on benchmark datasets.
基金supported by the National High-tech R&D Program("863"Program)of China(No.2013AA013505)the National Science Foundation of China(No.61472213)State Scholarship Fund from China Scholarship Council(No.201406210270)
文摘The basic function of the Internet is to delivery data(what) to serve the needs of all applications. IP names the attachment points(where) to facilitate ubiquitous interconnectivity as the current way to deliver data. The fundamental mismatch between data delivery and naming attachment points leads to a lot of challenges, e.g., mapping from data name to IP address, handling dynamics of underlying topology, scaling up the data distribution, and securing communication, etc. Informationcentric networking(ICN) is proposed to shift the focus of communication paradigm from where to what, by making the named data the first-class citizen in the network, The basic consensus of ICN is to name the data independent from its container(space dimension) and session(time dimension), which breaks the limitation of point-to-point IP semantic. It scales up data distribution by utilizing available resources, and facilitates communication to fit diverse connectivity and heterogeneous networks. However, there are only a few consensuses on the detailed design of ICN, and quite a few different ICN architectures are proposed. This paper reveals the rationales of ICN from the perspective of the Internet evolution, surveys different design choices, and discusses on two debatable topics in ICN, i.e.,self-certifying versus hierarchical names, and edge versus pervasive caching. We hope this survey helps clarify some mis-understandings on ICN and achieve more consensuses.
基金the support of the National Natural Science Foundation of China(No.41661038)Soft Science Research Project of Science and Technology Department of Qinghai province(No.2015-ZJ-602)
文摘The Ecological-living-productive land(ELPL)classification system was proposed in an effort to steer China's land pattern to an ecological-centered path,with the development model shifting from a single function into more integrated multifunction land use.The focus is coordinating the man-land contradictions and developing an intensive,efficient and sustainable land use policy in an increasingly tense relationship between humans and nature.Driven by socioeconomic change and rapid population growth,many cities are undergoing urban sprawl,which involves the consumption of cropland and ecological land and threatens the ecological balance.This paper aims to quantitatively analyze the critical effects of ELPL changes on eco-environmental quality according to land use classification based on leading function of ecology,living and production from 1990 to 2015 with a case study of Xining City.Also,four future land use scenarios were simulated for 2030 using the Future Land Use Simulation(FLUS)model that couples human and natural effects.Our results show a decrease in productive land(PL)and an increase in ecological land(EL)and living land(LL)in Xining City.Forestry ecological land(FEL)covered the top largest proportion;agriculture productive land(APL)showed the greatest reduction and urban and rural living land(U-RLL)presented a dramatic increase.The eco-environmental quality improved in 1990-2010,mainly affected by the conversion of APL to FEL and GEL.However,the encroachment of U-RLL into APL,other ecological land(OEL)and FEL was the main contributor to the decline in eco-environmental quality in 2010-2015 as well as the primary reason for the increase area of lower-quality.The Harmonious Development(HD)-Scenario,characterized by a rational allocation of LL and PL and a better eco-environment,would have implications for planning and monitoring future management of ELPL,and may represent a valuable reference for local policy-makers.
基金supported by the National Natural Science Foundation of China (Grant Nos. 11522328, 11473070, 11427803 and U1731241)the CAS Strategic Pioneer Program on Space Science (Grant Nos. XDA15010600, XDA15052200, XDA15320103 and XDA15320301)the National Key Research and Development Program (2018YFA0404202)
文摘The Lyman-alpha Solar Telescope(LST)is one of the three payloads onboard the Advanced Space-based Solar Observatory(ASO-S)mission.It aims at imaging the Sun from the disk center up to 2.5 R⊙targeting solar eruptions,particularly coronal mass ejections(CMEs),solar flares,prominences/filaments and related phenomena,as well as the fast and slow solar wind.The most prominent speciality of LST is the simultaneous observation of the solar atmosphere in both Lyαand white light(WL)with high temporospatial resolution both on the solar disk and the inner corona.New observations in the Lyαline together with traditional WL observations will provide us with many new insights into solar eruptions and solar wind.LST consists of a Solar Corona Imager(SCI)with a field of view(FOV)of 1.1–2.5 R⊙,a Solar Disk Imager(SDI)and a full-disk White-light Solar Telescope(WST)with an identical FOV up to 1.2 R⊙.SCI has a dual waveband in Lyα(121.6±10 nm)and in WL(700±40 nm),while SDI works in the Lyαwaveband of 121.6±7.5 nm and WST works in the violet narrow-band continuum of 360±2.0 nm.To produce high quality science data,careful ground and in-flight calibrations are required.We present our methods for different calibrations including dark field correction,flat field correction,radiometry,instrumental polarization and optical geometry.Based on the data calibration,definitions of the data levels and processing procedures for the defined levels from raw data are described.Plasma physical diagnostics offer key ingredients to understand ejecta and plasma flows in the inner corona,as well as different features on the solar disk including flares,filaments,etc.Therefore,we are making efforts to develop various tools to detect the different features observed by LST,and then to derive their physical parameters,for example,the electron density and temperature of CMEs,the outflow velocity of the solar wind,and the hydrogen density and mass flows of prominences.Coordinated observations and data analyses with the coronagraphs onboard Solar Orbiter,PROBA-3,and Aditya are also briefly discussed.
基金Supported by National Key Research and Development Program of China(Grant No.2019YFB 1309800)National Natural Science Foundation of China(Grant Nos.62173197,91848206)Beijing Science&Technology Project(Grant No.Z191100008019008).
文摘With the advance of smart material science,robotics is evolving from rigid robots to soft robots.Compared to rigid robots,soft robots can safely interact with the environment,easily navigate in unstructured fields,and be minimized to operate in narrow spaces,owning to the new actuation and sensing technologies developed by the smart materials.In the review,different actuation and sensing technologies based on different smart materials are analyzed and summarized.According to the driving or feedback signals,actuators are categorized into electrically responsive actuators,thermally responsive actuators,magnetically responsive actuators,and photoresponsive actuators;sensors are categorized into resistive sensors,capacitive sensors,magnetic sensors,and optical waveguide sensors.After introducing the principle and several robotic prototypes of some typical materials in each category of the actuators and sensors.The advantages and disadvantages of the actuators and sensors are compared based on the categories,and their potential applications in robotics are also presented.
基金supported by the open fund project ‘Research of Information Service of Marine Sensor Web’ (Grant No.2011002)the project ‘Research on Channel-Characteristics-Oriented Data Transmission Algorithm in USNs’ of NSF of China (Grant No.61202403)the projects ‘Research of Making Regulation of Testing Technology of Device Interface’ and ‘Development and Application of Real-Time and Long-Term Observation Network Under Nearshore and Adjacent Marine Areas’ of Public science and Technology Research Funds Projects of Ocean(Grant No.201305033-6,No.201105030)
文摘A great deal of ocean sensor observation data exists, for a wide range of marine disciplines, derived from in situ and remote observing platforms, in real-time, near-real-time and delayed mode. Ocean monitoring is routinely completed using sensors and instruments. Standardization is the key requirement for exchanging information about ocean sensors and sensor data and for comparing and combining information from different sensor networks. One or more sensors are often physically integrated into a single ocean ‘instrument' device, which often brings in many challenges related to diverse sensor data formats, parameters units, different spatiotemporal resolution, application domains, data quality and sensors protocols. To face these challenges requires the standardization efforts aiming at facilitating the so-called Sensor Web, which making it easy to provide public access to sensor data and metadata information. In this paper, a Marine Sensor Web, based on SOA and EDA and integrating the MBARI's PUCK protocol, IEEE 1451 and OGC SWE 2.0, is illustrated with a five-layer architecture. The Web Service layer and Event Process layer are illustrated in detail with an actual example. The demo study has demonstrated that a standard-based system can be built to access sensors and marine instruments distributed globally using common Web browsers for monitoring the environment and oceanic conditions besides marine sensor data on the Web, this framework of Marine Sensor Web can also play an important role in many other domains' information integration.