Amid the global pursuit of innovative approaches to disease diagnosis and treatment,the interdisciplinary convergence of chemistry and biomedicine has emerged as a pivotal force driving advancements in the field.Cutti...Amid the global pursuit of innovative approaches to disease diagnosis and treatment,the interdisciplinary convergence of chemistry and biomedicine has emerged as a pivotal force driving advancements in the field.Cutting-edge technologies such as optical probes[1],nanotechnology[2],immunotherapy[3],and biosensors[4]are finding increasingly widespread application in disease diagnosis and treatment,sustaining intense interest from both academia and industry.Against this backdrop,the 5th Xihua Chemistry and Biomedicine Forum was successfully held at Xihua University(Chengdu)from July 12 to 15,2025,infusing new vitality into academic exchanges and innovative progress in this domain.展开更多
Ion migration capability and interfacial chemistry of solid polymer electrolytes(SPEs)in all-solid-state sodium metal batteries(ASSMBs)are closely related to the Na^(+)coordination environment.Herein,an electrostatic ...Ion migration capability and interfacial chemistry of solid polymer electrolytes(SPEs)in all-solid-state sodium metal batteries(ASSMBs)are closely related to the Na^(+)coordination environment.Herein,an electrostatic engineering strategy is proposed to regulate the Na^(+)coordinated structure by employing a fluorinated metal–organic framework as an electron-rich model.Theoretical and experimental results revealed that the abundant electron-rich F sites can accelerate the disassociation of Na-salt through electrostatic attraction to release free Na^(+),while forcing anions into a Na^(+)coordination structure though electrostatic repulsion to weaken the Na^(+)coordination with polymer,thus promoting rapid Na^(+)transport.The optimized anion-rich weak solvation structure fosters a stable inorganic-dominated solid–electrolyte interphase,significantly enhancing the interfacial stability toward Na anode.Consequently,the Na/Na symmetric cell delivered stable Na plating/stripping over 2500 h at 0.1 mA cm^(−2).Impressively,the assembled ASSMBs demonstrated stable performance of over 2000 cycles even under high rate of 2 C with capacity retention nearly 100%,surpassing most reported ASSMBs using various solid-state electrolytes.This work provides a new avenue for regulating the Na^(+)coordination structure of SPEs by exploration of electrostatic effect engineering to achieve high-performance all-solid-state alkali metal batteries.展开更多
Natural enzymes are able to precisely bind substrates and catalyze activities because of their distinct framework structures.To mimic this ability,chemists are designing framework structures that resemble real enzymes...Natural enzymes are able to precisely bind substrates and catalyze activities because of their distinct framework structures.To mimic this ability,chemists are designing framework structures that resemble real enzymes.The use of metal-organic frameworks(MOFs)to mimic natural enzymes has advanced recently;this paper reviews these developments.This research specifically focuses on how the catalytically active center of natural enzymes can be exactly replicated by carefully controlling the composition and structure of MOFs.By identifying and attaching to substrates,MOFs can accelerate changes in a manner akin to that of real enzymes.The role of MOFs in simulating catalytic processes,enzyme activity,and potential uses in brain chemistry are also investigated in this work.It also discusses the most recent MOF applications in detecting and treating chemical abnormalities of the brain.The report finishes with a discussion of future research areas and potential applications,providing useful insights for researchers in the subject.展开更多
Developing advanced polymer electrolytes in lithium metal batteries(LMBs)has gained significant attention because of their inherent safety advantages over liquid electrolytes,while still encountering great challenges ...Developing advanced polymer electrolytes in lithium metal batteries(LMBs)has gained significant attention because of their inherent safety advantages over liquid electrolytes,while still encountering great challenges in mitigating uneven lithium plating/stripping and dendrite growth.Previous efforts primarily focused on passive approaches to mechanically constrain lithium dendrite growth.Recent studies have revealed the significance and effectiveness of regulating supramolecular interactions between polymer chains and other electrolyte components for homogenizing lithium deposition and enhancing the interfacial stability.This report provides a timely critical review to cover recent inspiring advancements in this direction.We first summarize the origins of supramolecular interaction origins,strength-determining factors,and structure–property relationships to establish quantitative correlations between polymer composition and supramolecular interaction properties.Then the recent advances in regulating supramolecular interaction chemistry are comprehensively discussed,focusing on those towards accelerated mass transport and stabilized anode-electrolyte interface.Finally,the remaining challenges are highlighted,and potential future directions in supramolecular interaction regulation of polymer electrolytes are prospected for the practical application of LMBs.展开更多
Aqueous batteries with metal anodes exhibit robust anodic capacities,but their energy densities are low because of the limited potential stabilities of aqueous electrolyte solutions.Current metal options,such as Zn an...Aqueous batteries with metal anodes exhibit robust anodic capacities,but their energy densities are low because of the limited potential stabilities of aqueous electrolyte solutions.Current metal options,such as Zn and Al,pose a dilemma:Zn lacks a sufficiently low redox potential,whereas Al tends to be strongly oxidized in aqueous environments.Our investigation introduces a novel rechargeable aqueous battery system based on Mn as the anode.We examine the effects of anions,electrolyte concentration,and diverse cathode chemistries.Notably,the ClO_(4)-based electrolyte solution exhibits improved deposition and dissolution efficiencies.Although stainless steel(SS 316 L)and Ni are stable current collectors for cathodes,they display limitations as anodes.However,using Ti as the anode resulted in increased Mn deposition and dissolution efficiencies.Moreover,we evaluate this system using various cathode materials,including Mn-intercalation-based inorganic(Ag0.33V2O5)and organic(perylenetetracarboxylic dianhydride)cathodes and an anionintercalation-chemistry(coronene)-based cathode.These configurations yield markedly higher output potentials compared to those of Zn metal batteries,highlighting the potential for an augmented energy density when using an Mn anode.This study outlines a systematic approach for use in optimizing metal anodes in Mn metal batteries,unlocking novel prospects for Mn-based batteries with diverse cathode chemistries.展开更多
Metal-sulfur electrochemistry represents a promising energy storage technology due to the natural abundance and unparalleled theoretical specific capacity of 1675 mAh g^(-1)of sulfur based on two-electron redox reacti...Metal-sulfur electrochemistry represents a promising energy storage technology due to the natural abundance and unparalleled theoretical specific capacity of 1675 mAh g^(-1)of sulfur based on two-electron redox reaction(S^(0)■S^(2-)).Commercially viable metal-sulfur batteries(MSBs)are hindered by sluggish sulfur conversion kinetics,which reduce the utilization efficiency of sulfur and lead to polysulfide shuttling.Single-atom catalysts(SACs)exhibit specific catalytic activity,a high atomic utilization ratio,and flexible selectivity,and are considered exceptional electrocatalysts for addressing the intractable challenges encountered by the MSBs.This review summarizes the recent progress in SACs for boosting the sulfur electrochemistry in MSBs,focusing on sulfur host materials,modified separators and functional interlayers,and analyzes the in-depth mechanisms of SACs.Moreover,the correlation between the coordination environments and the intrinsic activity of SACs is discussed.Finally,the main challenges and potential research directions of SACs for high-energy-density and long-life MSBs are outlined.This study provides significant guidance for constructing novel SACs that can accelerate the sulfur conversion kinetics in MSBs.展开更多
Metal-carbon dioxide(CO_(2))batteries hold great promise for reducing greenhouse gas emissions and are regarded as one of the most promising energy storage techniques due to their efficiency advantages in CO_(2)recove...Metal-carbon dioxide(CO_(2))batteries hold great promise for reducing greenhouse gas emissions and are regarded as one of the most promising energy storage techniques due to their efficiency advantages in CO_(2)recovery and conversion.Moreover,rechargeable nonaqueous metal-CO_(2)batteries have attracted much attention due to their high theoretical energy density.However,the stability issues of the electrode-electrolyte interfaces of nonaqueous metal-CO_(2)(lithium(Li)/sodium(Na)/potassium(K)-CO_(2))batteries have been troubling its development,and a large number of related research in the field of electrolytes have conducted in recent years.This review retraces the short but rapid research history of nonaqueous metal-CO_(2)batteries with a detailed electrochemical mechanism analysis.Then it focuses on the basic characteristics and design principles of electrolytes,summarizes the latest achievements of various types of electrolytes in a timely manner and deeply analyzes the construction strategies of stable electrode-electrolyte interfaces for metal-CO_(2)batteries.Finally,the key issues related to electrolytes and interface engineering are fully discussed and several potential directions for future research are proposed.This review enriches a comprehensive understanding of electrolytes and interface engineering toward the practical applications of next-generation metal-CO_(2)batteries.展开更多
Biomass-based hydrocarbon fuels,as one of the alternatives to traditional fossil fuels,have attracted considerable attention in the energy field due to their renewability and environmental benefits.This article provid...Biomass-based hydrocarbon fuels,as one of the alternatives to traditional fossil fuels,have attracted considerable attention in the energy field due to their renewability and environmental benefits.This article provides a systematic review of recent research progress in the chemical synthesis of biomass-based hydrocarbon fuels.It outlines the conversion pathways using feedstocks such as lipids,terpenoids,cellulose/hemicellulose,and lignin.Depending on the feedstock,various products with distinct structural characteristics can be prepared through reactions such as cyclization,condensation,and catalytic hydrogenation.Throughout the synthesis process,three key factors play a critical role:efficient catalyst development,production process optimization,and computational-chemistry-based molecular design.Finally,the article discusses future perspectives for biomass-based hydrocarbon fuel synthesis research.展开更多
A composite electrocatalyst,CoMoNiO-S/NF-110(NF is nickel foam),was synthesized through electrodeposition,followed by pyrolysis and then the vulcanization process.CoMoNiO-S/NF-110 exhibited a structure where Ni3S2 and...A composite electrocatalyst,CoMoNiO-S/NF-110(NF is nickel foam),was synthesized through electrodeposition,followed by pyrolysis and then the vulcanization process.CoMoNiO-S/NF-110 exhibited a structure where Ni3S2 and Mo2S3 nanoparticles were integrated at the edges of Co3O4 nanosheets,creating a rich,heterogeneous interface that enhances the synergistic effects of each component.In an alkaline electrolyte,the synthesized CoMoNiO-S/NF-110 exhibited superior electrocatalytic performance for oxygen evolution reaction(OER),achieving current densities of 100 and 200 mA·cm^(-2) with low overpotentials of 199.4 and 224.4 mV,respectively,outperforming RuO2 and several high-performance Mo and Ni-based catalysts.This excellent performance is attributed to the rich interface formed between the components and active sites exposed by the defect structure.展开更多
An upconversion nanoparticle(NaErF_(4)∶Yb/Tm@NaLuF_(4)∶Yb@NaLuF_(4)∶Nd/Yb@NaLuF_(4),noted as UC)was designed,emitting strong red light by 808 nm laser.The mesoporous silica(mSiO_(2))shell co‑doped with chlorin e6(C...An upconversion nanoparticle(NaErF_(4)∶Yb/Tm@NaLuF_(4)∶Yb@NaLuF_(4)∶Nd/Yb@NaLuF_(4),noted as UC)was designed,emitting strong red light by 808 nm laser.The mesoporous silica(mSiO_(2))shell co‑doped with chlorin e6(Ce6)and triethoxy(1H,1H,2H,2H‑nonafluorohexyl)silane(TFS)was coated on the outer layer of UC,and then a layer of HKUST‑1 shell was coated.The obtained nanocomposite UC@Ce6/TFS@mSiO_(2)@HKUST‑1(noted as UCTSH)was used for the synergistic treatment of chemodynamic therapy(CDT)and photodynamic therapy(PDT).Interestingly,the nanostructures can specifically re lease Cu^(2+)in the acidic tumor microenvironment.Cu^(2+)reacts with excess hydrogen peroxide(H_(2)O_(2))in the tumor microenvironment to form cytotoxic hydroxyl radical.Secondly,Ce6,with the action of oxygen‑carrying TFS,selectively produces a large amount of singlet oxygen by 808 nm laser irradiation.UCTSH can enhance the anti‑tumor effects of PDT and CDT by increasing the production level of reactive oxygen species,without causing damage to normal cells.展开更多
Fluorescent probes based on intramolecular charge transfer(ICT) have obvious advantages for accurate quantitative analysis.To obtain high-performance ratiometric probes requires distinct photophysical properties durin...Fluorescent probes based on intramolecular charge transfer(ICT) have obvious advantages for accurate quantitative analysis.To obtain high-performance ratiometric probes requires distinct photophysical properties during recognition reaction process,which is closely related to their ICT characteristics.1,8-Naphthalimide is known as a typical fluorophore with desirable ICT property when functionalized with an electron-donating moiety at the para-position of the naphthalene chromophore.Although the photophysical properties of para-substituted 1,8-naphthalimide have been well studied,its meta-substituted counterpart has not been fully evaluated since the meta-position is conventionally thought to be weakly conjugated.Herein,combined experimental and theoretical studies are performed which consistently indicate that stronger charge transfer(CT) is exhibited by the meta-amino substituted 1,8-naphthalimide(m-NH_(2)) compared to the para-amino substituted one(p-NH_(2)).The ratiometric response of fluorescence with significant changes in wavelength and intensity upon acetylation(m-NAc and p-NAc) can be attributed to the larger ICT and stronger-NH_(2) vibrations.This observation is further demonstrated by deuterium oxide experiments,viscosity experiments and quantum chemical calculations.The practical application of meta-amino-1,8-naphthalimide ICT-based probes is also confirmed.This research is expected to bring an in-depth understanding of π-conjugated systems with ICT characteristics,and facilitates the design of sensitive ICT fluorescent probes with meta-amino substitution.展开更多
The poor electrical conductivity of metal-organic frameworks(MOFs)limits their electrocatalytic performance in the oxygen evolution reaction(OER).In this study,a Py@Co-MOF composite material based on pyrene(Py)molecul...The poor electrical conductivity of metal-organic frameworks(MOFs)limits their electrocatalytic performance in the oxygen evolution reaction(OER).In this study,a Py@Co-MOF composite material based on pyrene(Py)molecules and{[Co2(BINDI)(DMA)_(2)]·DMA}_(n)(Co-MOF,H4BINDI=N,N'-bis(5-isophthalic acid)naphthalenediimide,DMA=N,N-dimethylacetamide)was synthesized via a one-pot method,leveragingπ-πinteractions between pyrene and Co-MOF to modulate electrical conductivity.Results demonstrate that the Py@Co-MOF catalyst exhibited significantly enhanced OER performance compared to pure Co-MOF or pyrene-based electrodes,achieving an overpotential of 246 mV at a current density of 10 mA·cm^(-2) along with excellent stability.Density functional theory(DFT)calculations reveal that the formation of O*in the second step is the rate-determining step(RDS)during the OER process on Co-MOF,with an energy barrier of 0.85 eV due to the weak adsorption affinity of the OH*intermediate for Co sites.CCDC:2419276.展开更多
Plantago major L.,commonly known as plantain,waybread,or dooryard plantain,is a versatile medicinal plant with multiple therapeutic applications.Traditionally,various parts of the plant have been formulated into syrup...Plantago major L.,commonly known as plantain,waybread,or dooryard plantain,is a versatile medicinal plant with multiple therapeutic applications.Traditionally,various parts of the plant have been formulated into syrups,drops,ointments,vaginal suppositories,gargles,and roasted preparations to treat diverse ailments,such as liver disorders,earaches,epilepsy,asthma,stomachaches,diarrhea,constipation,polymenorrhea,and uterine disorders.The plant contains clinically valuable bioactive compounds,including polysaccharides,flavonoids,lipids,iridoid glycosides,caffeic acid derivatives,terpenoids,alkaloids,and organic acids.These bioactive constituents are the primary contributors to the plant’s broad spectrum of biological activities,including antioxidant,anti-inflammatory,antibacterial,antidiarrheal,hepatoprotective,antiviral,antiphage,antinociceptive,antiulcerogenic,antigenotoxic,and immunomodulatory effects of the plant.This review comprehensively summarizes the phytochemical composition,traditional medicinal applications,and biological properties of this multifunctional medicinal plant.展开更多
Protein aggregates,mitochondrial import stress and neurodegenerative disorders:A salient hallmark of several neurodegenerative diseases,including Parkinson’s disease,is the abundance of protein aggregates(Goiran et a...Protein aggregates,mitochondrial import stress and neurodegenerative disorders:A salient hallmark of several neurodegenerative diseases,including Parkinson’s disease,is the abundance of protein aggregates(Goiran et al.,2022).This molecular event is believed to lead to activation of stress pathways ultimately resulting in cellular dysfunction(Eldeeb et al.,2022).Accordingly,many lines of research investigations focused on dampening the formation of protein aggregates or augmenting the clearance of protein aggregates as a potential therapeutic strategy to counteract the progression of neurodegenerative diseases,albeit with little success(Costa-Mattioli and Walter,2020).Cell stress cues such as the accumulation of protein aggregates lead to the activation of stress response pathways that aid cells in responding to the damage.Despite the notion that the transient activation of these pathways helps cells cope with stressors,persistent activation can induce unwanted apoptosis of cells and reduce overall tissue strength as well as lead to an accumulation of aggregation-prone proteins(Hetz and Papa,2018).Mutations in proteins involved in stress signaling termination can cause conditions like ataxia and early-onset dementia(Conroy et al.,2014).Therefore,it is crucial for stress response signaling to be turned off once conditions have improved.Nevertheless,the mechanisms by which cells silence these signals are still elusive.展开更多
Organic pollutants,a pivotal factor in water pollution,have persistently menaced the aquatic ecosystem,as well as the sustainable development of human health,economy,and society.Consequently,there is an urgent need fo...Organic pollutants,a pivotal factor in water pollution,have persistently menaced the aquatic ecosystem,as well as the sustainable development of human health,economy,and society.Consequently,there is an urgent need for advanced techniques to efficiently eliminate organic micropollutants from water.Here,we present the synthesis of three nonporous cavitand-crosslinked polymers capable of adsorbing diverse organic pollutants from aqueous solutions.These polymeric adsorbents exhibit outstanding adsorptive performance towards the tested micropollutants,characterized by high apparent adsorption rate constants(kobs)and maximum adsorption capacities(qmax,e).Notably,Compound NCCP-1 demonstrated a remarkable qmax,e of 459 mg/g for bisphenol A(BPA),ranking among the highest values reported for organic polymer adsorbents.In-depth investigation of the adsorption mechanism of the nonporous polymer revealed that it involves the recognition of pollutants by the deep cavities of the cavitand moieties and the interstitial spaces between them,primarily mediated by the hydrophobic effect.Furthermore,NCCP-1 was applied in situ water purification simulations and was proven to maintain its removal efficiency over more than four cycles,highlighting its potential for practical applications in water treatment.展开更多
Ceratopteris thalictroides (L.) Brongn (C. thalictroides), a fern from the Pteridaceae family, isan edible species that remains largely underutilized, even though it possesses a diverserange of applications. This revi...Ceratopteris thalictroides (L.) Brongn (C. thalictroides), a fern from the Pteridaceae family, isan edible species that remains largely underutilized, even though it possesses a diverserange of applications. This review aims to provide a comprehensive overview of itsgeographical distribution, ethnomedicinal applications, phytochemical constituents,pharmacological activities, and ecological importance. Various phytochemical analysesidentified the presence of phenols, flavonoids, alkaloids, terpenoids, and fatty acids from C.thalictroides, responsible for its multiple pharmacological properties, including antioxidant,antimicrobial, anti-inflammatory, anti-diabetic, and anticancer activities. Additionally, itsunique antheridiogen activity makes it a valuable model organism for plant genetics andreproductive studies. This review systematically summarizes the phytopharmacologicalpotential and ecological significance of C. thalictroides. The plant holds promise as a sourceof novel therapeutics and as a sustainable bioresource for pharmaceutical andenvironmental applications.展开更多
The sluggish kinetics of oxygen evolution reaction(OER)is a significant bottleneck for green hydrogen production via water electrolysis[1].Despite intensive efforts to develop advanced OER electrocatalysts featuring l...The sluggish kinetics of oxygen evolution reaction(OER)is a significant bottleneck for green hydrogen production via water electrolysis[1].Despite intensive efforts to develop advanced OER electrocatalysts featuring low noble-metal content and high activity,high overpotential and rapid degradation at high potentials persist.This inherent trade-off between activity and stability underscores the importance of designing catalysts that can deliver high OER activity at lower operating potentials,thereby efficiently mitigating dissolution and extending durability.展开更多
Organic and pharmaceutical synthesis have traditionally relied on the stepwise transformation ofactivated functional groups to synthesize cyclic molecules.The design of valuable heterocyclic compounds,for instance,has...Organic and pharmaceutical synthesis have traditionally relied on the stepwise transformation ofactivated functional groups to synthesize cyclic molecules.The design of valuable heterocyclic compounds,for instance,has depended on multi-step routes such as polar or radical cyclization,cycloadditions,and the manipulation of various functional groups to achieve ring formation or connection[1,2].展开更多
To realize the practical application of anion exchange membrane water electrolysis(AEMWE),it is essential to develop highly active,durable,and cost-effective electrocatalyst for oxygen evolution reaction(OER).Herein,w...To realize the practical application of anion exchange membrane water electrolysis(AEMWE),it is essential to develop highly active,durable,and cost-effective electrocatalyst for oxygen evolution reaction(OER).Herein,we report a hollow-structured Ni_(x)Co_(1−x)O/Ni_(3)S_(2)/Co_(9)S_(8)heterostructure synthesized via sequential template-assisted growth,thermal oxidation,and controlled sulfidation process.The abundant bimetallic heterointerfaces not only provide additional active sites but also promote electronic modulation via charge redistribution.Additionally,the porous and hollow architecture enhances active surface area and mass transfer ability,thereby increasing the number of accessible active sites for alkaline OER.As a result,the prepared electrocatalyst achieves low overpotential of 310 mV at 10 mA cm^(−2)and small Tafel slope of 55.94 mV dec^(−1),demonstrating the exceptional electrocatalytic performance for alkaline OER.When integrated as the anode in an AEMWE cell,it delivers outstanding performance with only 1.657 V at 1.0 A cm^(−2)and reaches high current density of 5.0 A cm^(−2)at 1.989 V,surpassing those of commercial RuO_(2).The cell also shows excellent long-term durability over 100 h with minimal degradation.This study highlights the strong potential of rationally engineered oxide/sulfide heterostructures for next-generation alkaline water electrolysis.展开更多
Quantifying the hydrogen bond(H-bond)strength of polymers is essential for rational design of advanced materials.However,direct measurement remains challenging because of the structural complexity of polymers and the ...Quantifying the hydrogen bond(H-bond)strength of polymers is essential for rational design of advanced materials.However,direct measurement remains challenging because of the structural complexity of polymers and the weak nature of H-bonds.Vacuum-based singlemolecule force spectroscopy(Vac-SMFS)offers a new and precise approach for such measurements.Using polyallylamine(PAAm)as a model polymer,the intrinsic strength(i.e.,strength without external influences)of representative N―H…N H-bonds was quantified to be about 5.25 kJ·mol^(–1).Comparative Vac-SMFS analysis across different polymer systems revealed that the N―H…N H-bonds in PAAm are unexpectedly stronger than the N―H…O H-bonds in poly(N-isopropylacrylamide)(PNIPAM)and the O―H…O H-bonds in poly(hydroxyethyl methacrylate)(PHEMA).This trend contrasts with that of established small-molecule systems.These results highlight how side-chain length and spatial configuration dictate polymer H-bond strengths,expanding the fundamental knowledge of polymer interactions and enabling the rational design of next-generation functional materials.展开更多
文摘Amid the global pursuit of innovative approaches to disease diagnosis and treatment,the interdisciplinary convergence of chemistry and biomedicine has emerged as a pivotal force driving advancements in the field.Cutting-edge technologies such as optical probes[1],nanotechnology[2],immunotherapy[3],and biosensors[4]are finding increasingly widespread application in disease diagnosis and treatment,sustaining intense interest from both academia and industry.Against this backdrop,the 5th Xihua Chemistry and Biomedicine Forum was successfully held at Xihua University(Chengdu)from July 12 to 15,2025,infusing new vitality into academic exchanges and innovative progress in this domain.
基金supported by the National Natural Science Foundation of China(No.52473213 and No.52203261)。
文摘Ion migration capability and interfacial chemistry of solid polymer electrolytes(SPEs)in all-solid-state sodium metal batteries(ASSMBs)are closely related to the Na^(+)coordination environment.Herein,an electrostatic engineering strategy is proposed to regulate the Na^(+)coordinated structure by employing a fluorinated metal–organic framework as an electron-rich model.Theoretical and experimental results revealed that the abundant electron-rich F sites can accelerate the disassociation of Na-salt through electrostatic attraction to release free Na^(+),while forcing anions into a Na^(+)coordination structure though electrostatic repulsion to weaken the Na^(+)coordination with polymer,thus promoting rapid Na^(+)transport.The optimized anion-rich weak solvation structure fosters a stable inorganic-dominated solid–electrolyte interphase,significantly enhancing the interfacial stability toward Na anode.Consequently,the Na/Na symmetric cell delivered stable Na plating/stripping over 2500 h at 0.1 mA cm^(−2).Impressively,the assembled ASSMBs demonstrated stable performance of over 2000 cycles even under high rate of 2 C with capacity retention nearly 100%,surpassing most reported ASSMBs using various solid-state electrolytes.This work provides a new avenue for regulating the Na^(+)coordination structure of SPEs by exploration of electrostatic effect engineering to achieve high-performance all-solid-state alkali metal batteries.
基金financially supported by the National Natural Science Foundation,China(Nos.22074095&22374103(Y.Lin))Beijing Natural Science Foundation(No.2222005(Y.Lin))。
文摘Natural enzymes are able to precisely bind substrates and catalyze activities because of their distinct framework structures.To mimic this ability,chemists are designing framework structures that resemble real enzymes.The use of metal-organic frameworks(MOFs)to mimic natural enzymes has advanced recently;this paper reviews these developments.This research specifically focuses on how the catalytically active center of natural enzymes can be exactly replicated by carefully controlling the composition and structure of MOFs.By identifying and attaching to substrates,MOFs can accelerate changes in a manner akin to that of real enzymes.The role of MOFs in simulating catalytic processes,enzyme activity,and potential uses in brain chemistry are also investigated in this work.It also discusses the most recent MOF applications in detecting and treating chemical abnormalities of the brain.The report finishes with a discussion of future research areas and potential applications,providing useful insights for researchers in the subject.
基金support from The Hong Kong Polytechnic University(U-CDCA)and Innovation and Technology Fund(ITS-322-23FP)。
文摘Developing advanced polymer electrolytes in lithium metal batteries(LMBs)has gained significant attention because of their inherent safety advantages over liquid electrolytes,while still encountering great challenges in mitigating uneven lithium plating/stripping and dendrite growth.Previous efforts primarily focused on passive approaches to mechanically constrain lithium dendrite growth.Recent studies have revealed the significance and effectiveness of regulating supramolecular interactions between polymer chains and other electrolyte components for homogenizing lithium deposition and enhancing the interfacial stability.This report provides a timely critical review to cover recent inspiring advancements in this direction.We first summarize the origins of supramolecular interaction origins,strength-determining factors,and structure–property relationships to establish quantitative correlations between polymer composition and supramolecular interaction properties.Then the recent advances in regulating supramolecular interaction chemistry are comprehensively discussed,focusing on those towards accelerated mass transport and stabilized anode-electrolyte interface.Finally,the remaining challenges are highlighted,and potential future directions in supramolecular interaction regulation of polymer electrolytes are prospected for the practical application of LMBs.
基金supported by the Global Joint Research Program funded by the Pukyong National University(202411790001)。
文摘Aqueous batteries with metal anodes exhibit robust anodic capacities,but their energy densities are low because of the limited potential stabilities of aqueous electrolyte solutions.Current metal options,such as Zn and Al,pose a dilemma:Zn lacks a sufficiently low redox potential,whereas Al tends to be strongly oxidized in aqueous environments.Our investigation introduces a novel rechargeable aqueous battery system based on Mn as the anode.We examine the effects of anions,electrolyte concentration,and diverse cathode chemistries.Notably,the ClO_(4)-based electrolyte solution exhibits improved deposition and dissolution efficiencies.Although stainless steel(SS 316 L)and Ni are stable current collectors for cathodes,they display limitations as anodes.However,using Ti as the anode resulted in increased Mn deposition and dissolution efficiencies.Moreover,we evaluate this system using various cathode materials,including Mn-intercalation-based inorganic(Ag0.33V2O5)and organic(perylenetetracarboxylic dianhydride)cathodes and an anionintercalation-chemistry(coronene)-based cathode.These configurations yield markedly higher output potentials compared to those of Zn metal batteries,highlighting the potential for an augmented energy density when using an Mn anode.This study outlines a systematic approach for use in optimizing metal anodes in Mn metal batteries,unlocking novel prospects for Mn-based batteries with diverse cathode chemistries.
基金financial support from the National Natural Science Foundation of China(No.22379001 and 22309003)the Natural Science Research Project of Anhui Province Education department(No.2022AH030046)the Top Young Talents of Anhui University of Technology,the Young Scholars of the Introduction and Education of Talents in Anhui Province,and the Scientific Research Foundation of Anhui University of Technology for Talent Introduction。
文摘Metal-sulfur electrochemistry represents a promising energy storage technology due to the natural abundance and unparalleled theoretical specific capacity of 1675 mAh g^(-1)of sulfur based on two-electron redox reaction(S^(0)■S^(2-)).Commercially viable metal-sulfur batteries(MSBs)are hindered by sluggish sulfur conversion kinetics,which reduce the utilization efficiency of sulfur and lead to polysulfide shuttling.Single-atom catalysts(SACs)exhibit specific catalytic activity,a high atomic utilization ratio,and flexible selectivity,and are considered exceptional electrocatalysts for addressing the intractable challenges encountered by the MSBs.This review summarizes the recent progress in SACs for boosting the sulfur electrochemistry in MSBs,focusing on sulfur host materials,modified separators and functional interlayers,and analyzes the in-depth mechanisms of SACs.Moreover,the correlation between the coordination environments and the intrinsic activity of SACs is discussed.Finally,the main challenges and potential research directions of SACs for high-energy-density and long-life MSBs are outlined.This study provides significant guidance for constructing novel SACs that can accelerate the sulfur conversion kinetics in MSBs.
基金supports from the Beijing Laboratory of New Energy Storage Technology, North China Electric Power Universitythe Program of the National Energy Storage Industry-Education Platformthe Interdisciplinary Innovation Program of North China Electric Power University (No. XM2212315)
文摘Metal-carbon dioxide(CO_(2))batteries hold great promise for reducing greenhouse gas emissions and are regarded as one of the most promising energy storage techniques due to their efficiency advantages in CO_(2)recovery and conversion.Moreover,rechargeable nonaqueous metal-CO_(2)batteries have attracted much attention due to their high theoretical energy density.However,the stability issues of the electrode-electrolyte interfaces of nonaqueous metal-CO_(2)(lithium(Li)/sodium(Na)/potassium(K)-CO_(2))batteries have been troubling its development,and a large number of related research in the field of electrolytes have conducted in recent years.This review retraces the short but rapid research history of nonaqueous metal-CO_(2)batteries with a detailed electrochemical mechanism analysis.Then it focuses on the basic characteristics and design principles of electrolytes,summarizes the latest achievements of various types of electrolytes in a timely manner and deeply analyzes the construction strategies of stable electrode-electrolyte interfaces for metal-CO_(2)batteries.Finally,the key issues related to electrolytes and interface engineering are fully discussed and several potential directions for future research are proposed.This review enriches a comprehensive understanding of electrolytes and interface engineering toward the practical applications of next-generation metal-CO_(2)batteries.
基金Support by National Natural Science Foundation of China(22127802,22573091)the HY Action(62402010305)。
文摘Biomass-based hydrocarbon fuels,as one of the alternatives to traditional fossil fuels,have attracted considerable attention in the energy field due to their renewability and environmental benefits.This article provides a systematic review of recent research progress in the chemical synthesis of biomass-based hydrocarbon fuels.It outlines the conversion pathways using feedstocks such as lipids,terpenoids,cellulose/hemicellulose,and lignin.Depending on the feedstock,various products with distinct structural characteristics can be prepared through reactions such as cyclization,condensation,and catalytic hydrogenation.Throughout the synthesis process,three key factors play a critical role:efficient catalyst development,production process optimization,and computational-chemistry-based molecular design.Finally,the article discusses future perspectives for biomass-based hydrocarbon fuel synthesis research.
文摘A composite electrocatalyst,CoMoNiO-S/NF-110(NF is nickel foam),was synthesized through electrodeposition,followed by pyrolysis and then the vulcanization process.CoMoNiO-S/NF-110 exhibited a structure where Ni3S2 and Mo2S3 nanoparticles were integrated at the edges of Co3O4 nanosheets,creating a rich,heterogeneous interface that enhances the synergistic effects of each component.In an alkaline electrolyte,the synthesized CoMoNiO-S/NF-110 exhibited superior electrocatalytic performance for oxygen evolution reaction(OER),achieving current densities of 100 and 200 mA·cm^(-2) with low overpotentials of 199.4 and 224.4 mV,respectively,outperforming RuO2 and several high-performance Mo and Ni-based catalysts.This excellent performance is attributed to the rich interface formed between the components and active sites exposed by the defect structure.
文摘An upconversion nanoparticle(NaErF_(4)∶Yb/Tm@NaLuF_(4)∶Yb@NaLuF_(4)∶Nd/Yb@NaLuF_(4),noted as UC)was designed,emitting strong red light by 808 nm laser.The mesoporous silica(mSiO_(2))shell co‑doped with chlorin e6(Ce6)and triethoxy(1H,1H,2H,2H‑nonafluorohexyl)silane(TFS)was coated on the outer layer of UC,and then a layer of HKUST‑1 shell was coated.The obtained nanocomposite UC@Ce6/TFS@mSiO_(2)@HKUST‑1(noted as UCTSH)was used for the synergistic treatment of chemodynamic therapy(CDT)and photodynamic therapy(PDT).Interestingly,the nanostructures can specifically re lease Cu^(2+)in the acidic tumor microenvironment.Cu^(2+)reacts with excess hydrogen peroxide(H_(2)O_(2))in the tumor microenvironment to form cytotoxic hydroxyl radical.Secondly,Ce6,with the action of oxygen‑carrying TFS,selectively produces a large amount of singlet oxygen by 808 nm laser irradiation.UCTSH can enhance the anti‑tumor effects of PDT and CDT by increasing the production level of reactive oxygen species,without causing damage to normal cells.
基金financially supported by National Key Research and Development Programs (Nos.2022YFD1700403 and 2023YFD1700303)National Natural Science Foundation of China (Nos.12274128 and 12250003)+2 种基金Shanghai Rising-Star Program (No.21QA1402600)the support of NYU-ECNU Center for Computational Chemistry at NYU Shanghaithe University of Bath and the Open Research Fund of the School of Chemistry and Chemical Engineering,Henan Normal University (No.2020ZD01) for support。
文摘Fluorescent probes based on intramolecular charge transfer(ICT) have obvious advantages for accurate quantitative analysis.To obtain high-performance ratiometric probes requires distinct photophysical properties during recognition reaction process,which is closely related to their ICT characteristics.1,8-Naphthalimide is known as a typical fluorophore with desirable ICT property when functionalized with an electron-donating moiety at the para-position of the naphthalene chromophore.Although the photophysical properties of para-substituted 1,8-naphthalimide have been well studied,its meta-substituted counterpart has not been fully evaluated since the meta-position is conventionally thought to be weakly conjugated.Herein,combined experimental and theoretical studies are performed which consistently indicate that stronger charge transfer(CT) is exhibited by the meta-amino substituted 1,8-naphthalimide(m-NH_(2)) compared to the para-amino substituted one(p-NH_(2)).The ratiometric response of fluorescence with significant changes in wavelength and intensity upon acetylation(m-NAc and p-NAc) can be attributed to the larger ICT and stronger-NH_(2) vibrations.This observation is further demonstrated by deuterium oxide experiments,viscosity experiments and quantum chemical calculations.The practical application of meta-amino-1,8-naphthalimide ICT-based probes is also confirmed.This research is expected to bring an in-depth understanding of π-conjugated systems with ICT characteristics,and facilitates the design of sensitive ICT fluorescent probes with meta-amino substitution.
文摘The poor electrical conductivity of metal-organic frameworks(MOFs)limits their electrocatalytic performance in the oxygen evolution reaction(OER).In this study,a Py@Co-MOF composite material based on pyrene(Py)molecules and{[Co2(BINDI)(DMA)_(2)]·DMA}_(n)(Co-MOF,H4BINDI=N,N'-bis(5-isophthalic acid)naphthalenediimide,DMA=N,N-dimethylacetamide)was synthesized via a one-pot method,leveragingπ-πinteractions between pyrene and Co-MOF to modulate electrical conductivity.Results demonstrate that the Py@Co-MOF catalyst exhibited significantly enhanced OER performance compared to pure Co-MOF or pyrene-based electrodes,achieving an overpotential of 246 mV at a current density of 10 mA·cm^(-2) along with excellent stability.Density functional theory(DFT)calculations reveal that the formation of O*in the second step is the rate-determining step(RDS)during the OER process on Co-MOF,with an energy barrier of 0.85 eV due to the weak adsorption affinity of the OH*intermediate for Co sites.CCDC:2419276.
文摘Plantago major L.,commonly known as plantain,waybread,or dooryard plantain,is a versatile medicinal plant with multiple therapeutic applications.Traditionally,various parts of the plant have been formulated into syrups,drops,ointments,vaginal suppositories,gargles,and roasted preparations to treat diverse ailments,such as liver disorders,earaches,epilepsy,asthma,stomachaches,diarrhea,constipation,polymenorrhea,and uterine disorders.The plant contains clinically valuable bioactive compounds,including polysaccharides,flavonoids,lipids,iridoid glycosides,caffeic acid derivatives,terpenoids,alkaloids,and organic acids.These bioactive constituents are the primary contributors to the plant’s broad spectrum of biological activities,including antioxidant,anti-inflammatory,antibacterial,antidiarrheal,hepatoprotective,antiviral,antiphage,antinociceptive,antiulcerogenic,antigenotoxic,and immunomodulatory effects of the plant.This review comprehensively summarizes the phytochemical composition,traditional medicinal applications,and biological properties of this multifunctional medicinal plant.
文摘Protein aggregates,mitochondrial import stress and neurodegenerative disorders:A salient hallmark of several neurodegenerative diseases,including Parkinson’s disease,is the abundance of protein aggregates(Goiran et al.,2022).This molecular event is believed to lead to activation of stress pathways ultimately resulting in cellular dysfunction(Eldeeb et al.,2022).Accordingly,many lines of research investigations focused on dampening the formation of protein aggregates or augmenting the clearance of protein aggregates as a potential therapeutic strategy to counteract the progression of neurodegenerative diseases,albeit with little success(Costa-Mattioli and Walter,2020).Cell stress cues such as the accumulation of protein aggregates lead to the activation of stress response pathways that aid cells in responding to the damage.Despite the notion that the transient activation of these pathways helps cells cope with stressors,persistent activation can induce unwanted apoptosis of cells and reduce overall tissue strength as well as lead to an accumulation of aggregation-prone proteins(Hetz and Papa,2018).Mutations in proteins involved in stress signaling termination can cause conditions like ataxia and early-onset dementia(Conroy et al.,2014).Therefore,it is crucial for stress response signaling to be turned off once conditions have improved.Nevertheless,the mechanisms by which cells silence these signals are still elusive.
基金supported by the National Natural Science Foundation of China(Nos.22322107,22101169 and 22071144)by Shanghai Scientific and Technological Committee(No.22010500300).
文摘Organic pollutants,a pivotal factor in water pollution,have persistently menaced the aquatic ecosystem,as well as the sustainable development of human health,economy,and society.Consequently,there is an urgent need for advanced techniques to efficiently eliminate organic micropollutants from water.Here,we present the synthesis of three nonporous cavitand-crosslinked polymers capable of adsorbing diverse organic pollutants from aqueous solutions.These polymeric adsorbents exhibit outstanding adsorptive performance towards the tested micropollutants,characterized by high apparent adsorption rate constants(kobs)and maximum adsorption capacities(qmax,e).Notably,Compound NCCP-1 demonstrated a remarkable qmax,e of 459 mg/g for bisphenol A(BPA),ranking among the highest values reported for organic polymer adsorbents.In-depth investigation of the adsorption mechanism of the nonporous polymer revealed that it involves the recognition of pollutants by the deep cavities of the cavitand moieties and the interstitial spaces between them,primarily mediated by the hydrophobic effect.Furthermore,NCCP-1 was applied in situ water purification simulations and was proven to maintain its removal efficiency over more than four cycles,highlighting its potential for practical applications in water treatment.
基金support and library facilities in accomplishing this part of the study.
文摘Ceratopteris thalictroides (L.) Brongn (C. thalictroides), a fern from the Pteridaceae family, isan edible species that remains largely underutilized, even though it possesses a diverserange of applications. This review aims to provide a comprehensive overview of itsgeographical distribution, ethnomedicinal applications, phytochemical constituents,pharmacological activities, and ecological importance. Various phytochemical analysesidentified the presence of phenols, flavonoids, alkaloids, terpenoids, and fatty acids from C.thalictroides, responsible for its multiple pharmacological properties, including antioxidant,antimicrobial, anti-inflammatory, anti-diabetic, and anticancer activities. Additionally, itsunique antheridiogen activity makes it a valuable model organism for plant genetics andreproductive studies. This review systematically summarizes the phytopharmacologicalpotential and ecological significance of C. thalictroides. The plant holds promise as a sourceof novel therapeutics and as a sustainable bioresource for pharmaceutical andenvironmental applications.
文摘The sluggish kinetics of oxygen evolution reaction(OER)is a significant bottleneck for green hydrogen production via water electrolysis[1].Despite intensive efforts to develop advanced OER electrocatalysts featuring low noble-metal content and high activity,high overpotential and rapid degradation at high potentials persist.This inherent trade-off between activity and stability underscores the importance of designing catalysts that can deliver high OER activity at lower operating potentials,thereby efficiently mitigating dissolution and extending durability.
基金supported by the MSIT(2022R1F1A106268,RS-2023-00213491,RS-2023-00219859,RS-2024-00405261,RS-2024-00409589,RS-2025-25460522,and RS-2025-00642970)Republic of Korea,the InnoCORE program of the Ministry of Science and ICT of Korea(N10250153 and 1.250022.01)the Creative Research Program and KAIST Cross-Generation Collaborative Lab Project.
文摘Organic and pharmaceutical synthesis have traditionally relied on the stepwise transformation ofactivated functional groups to synthesize cyclic molecules.The design of valuable heterocyclic compounds,for instance,has depended on multi-step routes such as polar or radical cyclization,cycloadditions,and the manipulation of various functional groups to achieve ring formation or connection[1,2].
基金supported by the Korea Institute for Advancement of Technology (KIAT)the Ministry of Trade,Industry&Energy (MOTIE) of the Republic of Korea (No. P0022130)by the Institute of Information&Communications Technology Planning&Evaluation(IITP)-Innovative Human Resource Development for Local Intellectualization program grant funded by the Korea government (MSIT)(IITP-2025-RS-2023-00259678)
文摘To realize the practical application of anion exchange membrane water electrolysis(AEMWE),it is essential to develop highly active,durable,and cost-effective electrocatalyst for oxygen evolution reaction(OER).Herein,we report a hollow-structured Ni_(x)Co_(1−x)O/Ni_(3)S_(2)/Co_(9)S_(8)heterostructure synthesized via sequential template-assisted growth,thermal oxidation,and controlled sulfidation process.The abundant bimetallic heterointerfaces not only provide additional active sites but also promote electronic modulation via charge redistribution.Additionally,the porous and hollow architecture enhances active surface area and mass transfer ability,thereby increasing the number of accessible active sites for alkaline OER.As a result,the prepared electrocatalyst achieves low overpotential of 310 mV at 10 mA cm^(−2)and small Tafel slope of 55.94 mV dec^(−1),demonstrating the exceptional electrocatalytic performance for alkaline OER.When integrated as the anode in an AEMWE cell,it delivers outstanding performance with only 1.657 V at 1.0 A cm^(−2)and reaches high current density of 5.0 A cm^(−2)at 1.989 V,surpassing those of commercial RuO_(2).The cell also shows excellent long-term durability over 100 h with minimal degradation.This study highlights the strong potential of rationally engineered oxide/sulfide heterostructures for next-generation alkaline water electrolysis.
基金financially supported by the National Natural Science Foundation of China(No.22273079)Fundamental Research Funds for the Central Universities(No.2682025ZTPY004)。
文摘Quantifying the hydrogen bond(H-bond)strength of polymers is essential for rational design of advanced materials.However,direct measurement remains challenging because of the structural complexity of polymers and the weak nature of H-bonds.Vacuum-based singlemolecule force spectroscopy(Vac-SMFS)offers a new and precise approach for such measurements.Using polyallylamine(PAAm)as a model polymer,the intrinsic strength(i.e.,strength without external influences)of representative N―H…N H-bonds was quantified to be about 5.25 kJ·mol^(–1).Comparative Vac-SMFS analysis across different polymer systems revealed that the N―H…N H-bonds in PAAm are unexpectedly stronger than the N―H…O H-bonds in poly(N-isopropylacrylamide)(PNIPAM)and the O―H…O H-bonds in poly(hydroxyethyl methacrylate)(PHEMA).This trend contrasts with that of established small-molecule systems.These results highlight how side-chain length and spatial configuration dictate polymer H-bond strengths,expanding the fundamental knowledge of polymer interactions and enabling the rational design of next-generation functional materials.
