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Optimizing Fine-Tuning in Quantized Language Models:An In-Depth Analysis of Key Variables
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作者 Ao Shen Zhiquan Lai +1 位作者 Dongsheng Li Xiaoyu Hu 《Computers, Materials & Continua》 SCIE EI 2025年第1期307-325,共19页
Large-scale Language Models(LLMs)have achieved significant breakthroughs in Natural Language Processing(NLP),driven by the pre-training and fine-tuning paradigm.While this approach allows models to specialize in speci... Large-scale Language Models(LLMs)have achieved significant breakthroughs in Natural Language Processing(NLP),driven by the pre-training and fine-tuning paradigm.While this approach allows models to specialize in specific tasks with reduced training costs,the substantial memory requirements during fine-tuning present a barrier to broader deployment.Parameter-Efficient Fine-Tuning(PEFT)techniques,such as Low-Rank Adaptation(LoRA),and parameter quantization methods have emerged as solutions to address these challenges by optimizing memory usage and computational efficiency.Among these,QLoRA,which combines PEFT and quantization,has demonstrated notable success in reducing memory footprints during fine-tuning,prompting the development of various QLoRA variants.Despite these advancements,the quantitative impact of key variables on the fine-tuning performance of quantized LLMs remains underexplored.This study presents a comprehensive analysis of these key variables,focusing on their influence across different layer types and depths within LLM architectures.Our investigation uncovers several critical findings:(1)Larger layers,such as MLP layers,can maintain performance despite reductions in adapter rank,while smaller layers,like self-attention layers,aremore sensitive to such changes;(2)The effectiveness of balancing factors depends more on specific values rather than layer type or depth;(3)In quantization-aware fine-tuning,larger layers can effectively utilize smaller adapters,whereas smaller layers struggle to do so.These insights suggest that layer type is a more significant determinant of fine-tuning success than layer depth when optimizing quantized LLMs.Moreover,for the same discount of trainable parameters,reducing the trainable parameters in a larger layer is more effective in preserving fine-tuning accuracy than in a smaller one.This study provides valuable guidance for more efficient fine-tuning strategies and opens avenues for further research into optimizing LLM fine-tuning in resource-constrained environments. 展开更多
关键词 Large-scale Language Model Parameter-Efficient Fine-Tuning parameter quantization key variable trainable parameters experimental analysis
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Sludge Management: Integrating the Principle of Circular Economy into the Concept of Sustainability
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作者 Ludovico Spinosa 《Journal of Environmental Science and Engineering(A)》 CAS 2025年第1期53-59,共7页
The development of sustainable sludge management systems requires looking at them with a new vision in which the concepts of SD(Sustainable Development)must integrate those of CE(Circular Economy),both concepts subjec... The development of sustainable sludge management systems requires looking at them with a new vision in which the concepts of SD(Sustainable Development)must integrate those of CE(Circular Economy),both concepts subject to the principles of TD(Thermodynamics),thus allowing the adoption of actions that are all the more effective the more complete the evaluation of the social dimension has been.This involves a new“Way of thinking”which sees the sludge system as the“Locomotive”of the entire wastewater/sludge treatment train and is developed through“Ways of acting”which includes both“Technical”actions to maximize recoveries of useful materials and/or or energy,and“Socio/Institutional”actions to overcome barriers linked to local cultures and traditions,also considering that the specific local context heavily influences the choices capable of satisfying the concepts of CE.It follows the need of issuing realistic and applicable regulations and overcoming social barriers,such as lack of infrastructure and/or qualified personnel,to achieve an effective integration of the concepts of CE with the more general ones of sustainability. 展开更多
关键词 Circular economy REGULATION sludge management STANDARDIZATION sustainability.
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Investigation of spatiotemporal distribution and formation mechanisms of ozone pollution in eastern Chinese cities applying convolutional neural network 被引量:1
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作者 Qiaoli Wang Dongping Sheng +7 位作者 Chengzhi Wu Xiaojie Ou Shengdong Yao Jingkai Zhao Feili Li Wei Li Jianmeng Chen 《Journal of Environmental Sciences》 2025年第2期126-138,共13页
Severe ground-level ozone(O_(3))pollution over major Chinese cities has become one of the most challenging problems,which have deleterious effects on human health and the sustainability of society.This study explored ... Severe ground-level ozone(O_(3))pollution over major Chinese cities has become one of the most challenging problems,which have deleterious effects on human health and the sustainability of society.This study explored the spatiotemporal distribution characteristics of ground-level O_(3) and its precursors based on conventional pollutant and meteorological monitoring data in Zhejiang Province from 2016 to 2021.Then,a high-performance convolutional neural network(CNN)model was established by expanding the moment and the concentration variations to general factors.Finally,the response mechanism of O_(3) to the variation with crucial influencing factors is explored by controlling variables and interpolating target variables.The results indicated that the annual average MDA8-90th concentrations in Zhejiang Province are higher in the northern and lower in the southern.When the wind direction(WD)ranges from east to southwest and the wind speed(WS)ranges between 2 and 3 m/sec,higher O_(3) concentration prone to occur.At different temperatures(T),the O_(3) concentration showed a trend of first increasing and subsequently decreasing with increasing NO_(2) concentration,peaks at the NO_(2) concentration around 0.02mg/m^(3).The sensitivity of NO_(2) to O_(3) formation is not easily affected by temperature,barometric pressure and dew point temperature.Additionally,there is a minimum IRNO_(2) at each temperature when the NO_(2) concentration is 0.03 mg/m^(3),and this minimum IRNO_(2) decreases with increasing temperature.The study explores the response mechanism of O_(3) with the change of driving variables,which can provide a scientific foundation and methodological support for the targeted management of O_(3) pollution. 展开更多
关键词 OZONE Spatiotemporal distribution Convolutional neural network Ozone formation rules Incremental reactivity
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Model tests and numerical analysis of emergency treatment of cohesionless soil landslide with quick-setting polyurethane 被引量:1
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作者 ZHANG Zhichao TANG Xuefeng +2 位作者 HUANG Rufa CAI Zhenjie GAO Anhua 《Journal of Mountain Science》 2025年第1期110-121,共12页
Shotcrete is one of the common solutions for shallow sliding.It works by forming a protective layer with high strength and cementing the loose soil particles on the slope surface to prevent shallow sliding.However,the... Shotcrete is one of the common solutions for shallow sliding.It works by forming a protective layer with high strength and cementing the loose soil particles on the slope surface to prevent shallow sliding.However,the solidification time of conventional cement paste is long when shotcrete is used to treat cohesionless soil landslide.The idea of reinforcing slope with polyurethane solidified soil(i.e.,mixture of polyurethane and sand)was proposed.Model tests and finite element analysis were carried out to study the effectiveness of the proposed new method on the emergency treatment of cohesionless soil landslide.Surcharge loading on the crest of the slope was applied step by step until landslide was triggered so as to test and compare the stability and bearing capacity of slope models with different conditions.The simulated slope displacements were relatively close to the measured results,and the simulated slope deformation characteristics were in good agreement with the observed phenomena,which verifies the accuracy of the numerical method.Under the condition of surcharge loading on the crest of the slope,the unreinforced slope slid when the surcharge loading exceeded 30 k Pa,which presented a failure mode of local instability and collapse at the shallow layer of slope top.The reinforced slope remained stable even when the surcharge loading reached 48 k Pa.The displacement of the reinforced slope was reduced by more than 95%.Overall,this study verifies the effectiveness of polyurethane in the emergency treatment of cohesionless soil landslide and should have broad application prospects in the field of geological disasters concerning the safety of people's live. 展开更多
关键词 Cohesionless soil landslide POLYURETHANE Emergency treatment Reinforcement effect Model test Finite element analysis
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Top Ten Events in the Natural Gas Industry in China for 2024
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作者 Xu Bo Zhu Qiang 《China Oil & Gas》 2025年第2期53-58,共6页
In 2024,China’s natural gas industry continues to show a positive trend.In the field of exploration and development,a large ultra-deep water and ultra-shallow gas field has been discovered,further enhancing the uniqu... In 2024,China’s natural gas industry continues to show a positive trend.In the field of exploration and development,a large ultra-deep water and ultra-shallow gas field has been discovered,further enhancing the unique deep-water complex oil and gas exploration and development technology system independently developed by China.Remarkable achievements have been made in offshore development,including the commissioning of Deep Sea No.1 PhaseⅡ,the first deep-water high-pressure gas field.Additionally,the establishment of the Daji gas field,the first onshore coal rock gas field with an oil and gas equivalent of one million tons,provides strong support for domestic natural gas production.In terms of infrastructure construction,the entire China-Russia east-route natural gas pipeline has been completed,the Xinjiang section of the West Fourth Line is now operational,the Southern Xinjiang Gas Pipeline project has been fully launched,and five new or expanded LNG receiving terminals have been added,increasing the annual receiving capacity by 21.10 million tons.In the field of related equipment manufacturing,China successfully delivered the first vessel of its largest LNG transportation ship construction project,the Greenergy Ocean,and successfully launched its first large-scale floating natural gas liquefaction facility,the NGUYA FLNG.In terms of market supply and demand,natural gas consumption exceeded 400 billion m^(3) for the first time,with apparent consumption reaching 412.43 billion m^(3),an increase of 24.9 billion m^(3) year-on-year,reflecting a growth rate of 6.4%.The total supply reached 424.3 billion m^(3),an increase of 27.5 billion m^(3) year-on-year,with a growth rate of 7.5%.In terms of regulatory policy,China has once again issued a natural gas utilization policy aimed at further guiding the orderly and efficient development of the natural gas market. 展开更多
关键词 natural gas exploration development offshore developmentincluding ultra shallow gas field deep water complex oil gas exploration ultra deep water offshore development exploration developmenta
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编织之韵2025年大阪·关西世博会菲律宾馆
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作者 麦子(编译) 《室内设计与装修》 2025年第7期72-74,共3页
2025年大阪·关西世博会菲律宾馆的设计灵感源于“编织”这一隐喻的概念。其建筑结构映射了经线和纬线,而这2种编织中的基本元素正象征着社区、团结与创造力的恒久力量。场馆由超过1000片手工制作的藤条编织单元组成,表达出线的意向... 2025年大阪·关西世博会菲律宾馆的设计灵感源于“编织”这一隐喻的概念。其建筑结构映射了经线和纬线,而这2种编织中的基本元素正象征着社区、团结与创造力的恒久力量。场馆由超过1000片手工制作的藤条编织单元组成,表达出线的意向,展现了编织工艺的可扩展性,突破了传统家具尺度的表达,并在建筑规模上呈现无限可能的潜力。这一建筑作品见证了手工技艺的未来,强调其在不断发展的数字化景观中的重要意义,并颂扬了菲律宾手工艺品牌中蕴含的匠心精神。编织的藤条单元像线一样蜿蜒于建筑立面之上,营造出持续运动的视觉效果,也表达了不断进步的姿态。 展开更多
关键词 手工制作 社区 经线 菲律宾馆 建筑结构 藤条 纬线
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The Cyberpsychology of Small and Medium-Sized Enterprises Cybersecurity: A Human-Centric Approach to Policy Development
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作者 Troy C. Troublefield 《Journal of Information Security》 2025年第1期158-183,共26页
This study investigates the critical intersection of cyberpsychology and cybersecurity policy development in small and medium-sized enterprises (SMEs). Through a mixed-methods approach incorporating surveys of 523 emp... This study investigates the critical intersection of cyberpsychology and cybersecurity policy development in small and medium-sized enterprises (SMEs). Through a mixed-methods approach incorporating surveys of 523 employees across 78 SMEs, qualitative interviews, and case studies, the research examines how psychological factors influence cybersecurity behaviors and policy effectiveness. Key findings reveal significant correlations between psychological factors and security outcomes, including the relationship between self-efficacy and policy compliance (r = 0.42, p β = 0.37, p < 0.001). The study identifies critical challenges in risk perception, policy complexity, and organizational culture affecting SME cybersecurity implementation. Results demonstrate that successful cybersecurity initiatives require the integration of psychological principles with technical solutions. The research provides a framework for developing human-centric security policies that address both behavioral and technical aspects of cybersecurity in resource-constrained environments. 展开更多
关键词 Cyberpsychology CYBERSECURITY SMES Policy Development Human Factors Risk Perception Compliance Behavior Organizational Culture Psychological Resilience Security Awareness
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Social Safety Nets and Their Effectiveness in Poverty Alleviation:Evidence from Banadir Region,Somalia
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作者 Elmi Hassan Samatar 《Journal of Environmental & Earth Sciences》 2025年第3期77-87,共11页
The paper primarily focuses on social safety nets and their effectiveness in poverty alleviation.Social Safety Net(SSN)programs pertain to social service initiatives aimed at providing temporary assistance to individu... The paper primarily focuses on social safety nets and their effectiveness in poverty alleviation.Social Safety Net(SSN)programs pertain to social service initiatives aimed at providing temporary assistance to individuals or groups facing vulnerabilities or unexpected hardships,such as those with lower incomes.Poverty poses a significant obstacle to the progress of social development,and its impacts are worsened by various factors including insecurity,frequent flooding,and droughts in Somalia.A total of 342 households in the Banadir region of Somalia were interviewed for the social safety nets(SSN)study.Data collection in the study was facilitated through the utilization of Kobo Toolbox,while the data analysis was conducted using EViews v.12.The results obtained from the ADP and PP tests indicated that all variables exhibited stationarity at the level.The Impact Assessment(IA)reveals a positive correlation with Household Income and Poverty Indices(HIPI),suggesting a risk of dependency without a strategic exit strategy,potentially leading to a 26%increase in poverty levels.A well-executed Program Implementation and Design(PID)can result in a 33%increase in income and poverty indices.Recipients perceive the Social Safety Net(PSSN)as reducing poverty and increasing income by 11%.Therefore,the study recommends integrating beneficiaries into the urban economy through sustainable livelihood options.Finally,the Somali government should prioritize the implementation of sustainable livelihood programs to mitigate dependency and alleviate poverty among SSN beneficiaries. 展开更多
关键词 Social Safety Nets(SSNs) Poverty Alleviation Household Income Agriculture Income Generation Activities(IGAs) Sustainable Livelihoods Banadir Region SOMALIA
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The Guardian of the Grand Canal
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作者 REN DEYONG 《China Today》 2025年第8期60-62,共3页
A precious heritage from ancient times,the Beijing-Hangzhou Grand Canal has renewed its former glory through ecological rehabilitation and cultural preservation over the past decades.
关键词 cultural preservation ecological rehabilitation ancient heritage beijing hangzhou grand canal ecological rehabilitation cultural preservation
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Use of Polymeric Materials in Construction to Improve Durability & Sustainability
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作者 Waseem Ahmad Khatri Mohammed Al Mehthel +2 位作者 Oscar Salazar Mirza Baig Saleh Al Wohaibi 《World Journal of Engineering and Technology》 2025年第1期12-38,共27页
Building and construction sector, including infrastructures, are facing many challenges which are scarcity of raw materials, CO2 emissions, lower construction efficiency, and deterioration under corrosive environment ... Building and construction sector, including infrastructures, are facing many challenges which are scarcity of raw materials, CO2 emissions, lower construction efficiency, and deterioration under corrosive environment that cost the world economy $2.5 trillion and this translates to 3.4% of world gross domestic product. This paper presents several examples that show how the use of the nonmetallic materials improved sustainability and life cycles in the built environment by removing the corrosion issue from its root and using durable NM polymers in construction. The paper details recently patented Aramco technology for the use of nonmetallic paving panels that could be used as an alternative to concrete and asphalt paving. Other case studies presented cover use of GFRP Poles for traffic signs and signal poles to replace traditional steel poles. Details of developments for specialist structural application in bridges, in architectural applications, polymers in soils, fibers in pavement manholes and bendable concrete are presented. 展开更多
关键词 Non-Metallic Materials Corrosion DURABILITY Non-Metallic Paving Metals Building and Construction Paving Panels Bridges ARCHITECTURAL Polymers Glass Fiber Reinforced Polymers (GFRP)
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全球木器涂料市场:正在发展
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作者 Jorge Prieto 《中国涂料》 2025年第4期74-76,共3页
全球木器涂料市场代表了一个重要的涂料领域,专注于室内和室外应用中使用的木器组件的整理和保护。本文阐释了2024年全球木器涂料市场发展情况。装饰木器涂料和工业木器涂料之间有一个基本的区别。装饰木器涂料市场包括室内和室外建筑... 全球木器涂料市场代表了一个重要的涂料领域,专注于室内和室外应用中使用的木器组件的整理和保护。本文阐释了2024年全球木器涂料市场发展情况。装饰木器涂料和工业木器涂料之间有一个基本的区别。装饰木器涂料市场包括室内和室外建筑中木器和木基材料的涂料,这些产品用于保护和增强美观。而另一方面,工业木器涂料市场侧重于工业制造木制品(如家具或地板)的涂料。在这里,重点通常聚焦于大规模生产和功能特性上。工业中使用的涂料产品通常针对各自涂料生产线的技术要求进行专门配制。 展开更多
关键词 2024年 装饰木器涂料 工业木器涂料 全球木器涂料市场
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Three key policy areas in urgent need of improvement for advancing China’s energy transition
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作者 Peng Li Jing Zhang 《iEnergy》 2025年第2期77-78,共2页
Remarkable achievements of the new energy industry policy framework over the past two decades Over the past two decades,the industry policy framework centered on the Renewable Energy Law has effectively facilitated th... Remarkable achievements of the new energy industry policy framework over the past two decades Over the past two decades,the industry policy framework centered on the Renewable Energy Law has effectively facilitated the leapfrog development of China’s new energy sector.During this period,policy incentives were primarily focused on promoting the rational scaling of the industry,thereby driving rapid technological upgrades and iterations.This,in turn,enabled a significant reduc-tion in the cost of new energy power generation.In this process,policy played a pivotal role in two key areas:first,by providing per-kilowatt-hour subsidies to bridge the cost gap between new energy and conventional power sources;and second,by exempting the system cost of new energy grid-connected operation through a full guaranteed purchase system. 展开更多
关键词 new energy new energy pow policy framework renewable energy law energy transition new energy industry industry policy framework
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The Role of Pigs in the Carbon Footprint of Red Meat in Canada
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作者 James A.Dyer Raymond L.Desjardins 《Journal of Environmental & Earth Sciences》 2025年第4期11-26,共16页
Global livestock production is a major driver of climate change.Lumping beef and pork together as red meat masks important differences in their carbon footprints,land uses,and social status.These two red meat choices ... Global livestock production is a major driver of climate change.Lumping beef and pork together as red meat masks important differences in their carbon footprints,land uses,and social status.These two red meat choices in Canada were compared by using a meta-model of the Unified Livestock Industry and Crop Emissions Estimation System(ULICEES).ULICEES calculated fossil CO_(2),N_(2)O and CH_(4) emissions for beef,dairy,pork,poultry,and sheep production in Canada,based on both the livestock and their supporting land base in 2001.The dynamic drivers of the meta-model were crop yields,breeding female populations,tillage practices,nitrogen fertilizer use,and the crop complex of each livestock industry.When the potential carbon sequestration in the land growing harvested perennial forage is credited to beef production,the CO_(2)e emissions offset does not reduce the carbon footprint of beef enough to match the lower carbon footprint of pork.Most of the land required to grow hay for beef would not be needed to feed a protein-equivalent pig population.In a hypothetical conversion of all beef production to pork production for 2021,4.5 Mha of land under perennial forage was freed and 10.0 MtCO_(2)e per year was mitigated when that area was re-cultivated for annual crops—a GHG mitigation equal to 12%of the GHG emissions budget of Canadian agriculture.Leaving that area under a perennial ground cover mitigated 19.8 MtCO_(2)e per year,the equivalent of 23%of the sector’s GHG emissions budget. 展开更多
关键词 PIGS Beef Cows PROTEIN Red Meat Climate Change Carbon Footprint Land Use Change
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Application Analysis of Growth Strategies for Industrial Automation Enterprises in the Automotive Manufacturing Sector
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作者 Honggang Liu 《Proceedings of Business and Economic Studies》 2025年第4期146-153,共8页
As the demand for intelligent and flexible production in the automotive manufacturing industry continues to intensify,industrial automation enterprises are gaining ever-greater market opportunities and competitive adv... As the demand for intelligent and flexible production in the automotive manufacturing industry continues to intensify,industrial automation enterprises are gaining ever-greater market opportunities and competitive advantages in this field.Based on a literature review and representative case studies,this paper constructs a theoretical framework for growth strategies and systematically analyzes the current application status and growth paths of automation enterprises in both complete vehicle and component production.The research finds that different growth strategies(such as vertical integration,horizontal diversification,and digital service transformation)exhibit varying applicability across upstream and downstream segments of automotive manufacturing,while simultaneously facing challenges related to technology integration,business models,and organizational change.In response to these issues,this paper proposes countermeasures such as optimizing R&D and customer relationship management,improving branding and after-sales service systems,and strengthening policy and industry environment support,thereby offering guidance for sustainable growth of industrial automation enterprises in the automotive manufacturing sector. 展开更多
关键词 Industrial automation Growth strategy Automotive manufacturing Smart manufacturing Case analysis
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Integrating a Unique Leg Strengthening Device (S-Press) into Physiotherapy Rehabilitation Practice, a Qualitative Examination
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作者 Kate Walker Chris Griffiths Bharath Lakkappa 《Advances in Aging Research》 2025年第1期1-21,共21页
Muscle deconditioning due to hospitalisation is problematic, causing delayed discharges, more nursing, carer, or social service support following discharge, and possible discharge to a care home rather than the patien... Muscle deconditioning due to hospitalisation is problematic, causing delayed discharges, more nursing, carer, or social service support following discharge, and possible discharge to a care home rather than the patient’s own home. Muscle deconditioning is associated with increased mortality, infections, depression, and reductions in patient mobility and ability to engage in their activities of daily living. Preserving muscle strength and function should form part of patients’ rehabilitation plans. Progressive resistance training (PRE) offers the most cost-effective way of preserving muscle strength and function;however, it is not routinely carried out in hospitals. A leg strengthening device (the S-Press) has been developed with the aim of improving access to effective PRE for adults. Using a qualitative approach, thematic analysis of interviews with physiotherapists, patients, and relative carers about their experience of using the S-Press provided insight into integrating PRE into patients’ rehabilitation, what promoted or prevented its use, and the outcomes associated with its use. Four overall themes emerged from the data. “Experience of Users” described that the S-Press was accessible, convenient, time efficient, portable, and manoeuvrable, and it provided an objective measure of progress. “Facilitators” included findings around how the S-Press was easy to use, motivational, and comfortable when in use. “Barriers” comprised the inability of some patients to use the S-Press independently and the identification of obstacles that prevented consistent use. “Impact and Benefits” represented the perceptions of increased leg strength and psychological benefits. The S-Press is beneficial for patients’ rehabilitation by offering PRE that is simple and easy to use, acceptable to both patients and professionals, and can be integrated as part of patients’ rehabilitation plans. 展开更多
关键词 PHYSIOTHERAPY REHABILITATION Strength Training DECONDITIONING Resistance Training
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Studies in Moisture Adsorption and Thickness Swelling:Low and High Humidity
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作者 Greg S.McLellan Ralph E.Moon 《Journal of Civil Engineering and Architecture》 2025年第2期53-65,共13页
Composite wood products(i.e.,particleboard,medium density fiberboard,oriented strand board,plywood)used in cabinets,shelving,and base trim express varying degrees of thickness swelling when exposed to a sustained mois... Composite wood products(i.e.,particleboard,medium density fiberboard,oriented strand board,plywood)used in cabinets,shelving,and base trim express varying degrees of thickness swelling when exposed to a sustained moisture source.Thickness swelling occurs when cellulose fibers adsorb water molecules and swell after attaining a moisture content of 29%to 36%.Observations of thickness swelling were made to refine water loss duration estimates.Thickness swell height is the result of several intrinsic factors(wood species,density,adhesive resin,heat pressing conditions).This study examined an extrinsic factor,humidity,at elevated(>95%RH)and ambient(50%RH)conditions.Specimens subjected to moisture for longer periods(8-10 weeks)experienced gradual darkening from accumulated biomass and fungal deterioration of the wood surfaces.The study revealed that high humidity conditions expressed higher rates of thickness swelling and that estimates of water loss duration should consider the influence of ambient humidity during and following a water release. 展开更多
关键词 Composite wood duration of loss moisture exposure thickness swell
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A New Dawn Rising:New Options for Windows,Facades&Walls with Vacuum Glass and Other Integrated Building Innovations
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作者 Helmut Hohenstein 《Journal of Civil Engineering and Architecture》 2025年第3期137-147,共11页
This year summarizes the experience of industrialization of vacuum glazing in the past twenty years.A series of technical difficulties have been solved to start the first global mass production of high-quality vacuum ... This year summarizes the experience of industrialization of vacuum glazing in the past twenty years.A series of technical difficulties have been solved to start the first global mass production of high-quality vacuum glass.High quality means high performance and long life which are interrelated.A mass production line must be able to achieve these two requirements if it is to produce vacuum glazing products that can be accepted by the society.With a U-value of 0.4 W/m²·K based on Low-E(low emissivity)with an emissivity of 0.03 the door is wide open for further solutions.Time,gradually to improve costs,maximizes output and develops innovative solutions of advanced window and façade systems combining complete new features like smart glasses,intelligent lamella systems in hybrid VG-IG solutions changing the building world towards“Energy plus Houses”.Market demand will rapidly increase with completely new options.Cost saving means to balance additional advantages for savings against system costs of window or façade elements.Due to promotion of energy saving and emission reduction,both,subjective and objective conditions for industrialization of vacuum glasses are perfect;the building world is waiting for it,since long.There is a lot to investigate and to gain for business success. 展开更多
关键词 Vacuum glass energy saving advanced window and façade systems industrial production Energy+Houses
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Evaluation of biological therapies in autoimmune hepatitis:A casebased systematic review
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作者 Haifa Eldew Jonathan Soldera 《World Journal of Gastrointestinal Pathophysiology》 2025年第1期1-13,共13页
BACKGROUND Autoimmune hepatitis(AIH)is typically treated with immunomodulators and steroids.However,some patients are refractory to these treatments,necessitating alternative approaches.Biological therapies have recen... BACKGROUND Autoimmune hepatitis(AIH)is typically treated with immunomodulators and steroids.However,some patients are refractory to these treatments,necessitating alternative approaches.Biological therapies have recently been explored for these difficult cases.AIM To assess the efficacy and safety of biologics in AIH,focusing on patients unresponsive to standard treatments and evaluating outcomes such as serological markers and histological remission.METHODS A case-based systematic review was performed following the PRISMA protocol to evaluate the efficacy and safety of biological therapies in AIH.The primary focus was on serological improvement and histological remission.The secondary focus was on assessing therapy safety and additional outcomes.A standardized search command was applied to MEDLINE,EMBASE,and Cochrane Library databases to identify relevant studies.Inclusion criteria encompassed adult AIH patients treated with biologics.Data were analyzed based on demographics,prior treatments,and therapy-related outcomes.A narrative synthesis was employed to address biases and provide a comprehensive overview of the evidence.RESULTS A total of 352 studies were reviewed,with 30 selected for detailed analysis.Key findings revealed that Belimumab led to a favourable response in five out of eight AIH patients across two studies.Rituximab demonstrated high efficacy,with 41 out of 45 patients showing significant improvement across six studies.Basiliximab was assessed in a single study,where the sole patient treated experienced a beneficial outcome.Additionally,a notable number of AIH cases were induced by anti-tumor necrosis factor(TNF)medications,including 16 cases associated with infliximab and four cases with adalimumab.All these cases showed improvement upon withdrawal of the biologic agent.CONCLUSION Belimumab and Rituximab show promise as effective alternatives for managing refractory AIH,demonstrating significant improvements in clinical outcomes and liver function.However,the variability in patient responses to different therapies highlights the need for personalized treatment strategies.The risk of AIH induced by anti-TNF therapies underscores the need for vigilant monitoring and prompt symptom recognition.These findings support the incorporation of biologic agents into AIH treatment protocols,particularly for patients who do not respond to conventional therapies. 展开更多
关键词 Autoimmune hepatitis Biological therapies BELIMUMAB RITUXIMAB BASILIXIMAB INFLIXIMAB ADALIMUMAB
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50 Practical Ways to Alter the Relative Efficiencies of Behaviors
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作者 Steve Ward Teresa Grimes 《Psychology Research》 2025年第2期37-53,共17页
Behavior analysts have long recognized the need to increase at least one behavior when attempting to decrease another and usually focus primarily upon increasing a wide variety of behaviors(White&Haring,1980).But ... Behavior analysts have long recognized the need to increase at least one behavior when attempting to decrease another and usually focus primarily upon increasing a wide variety of behaviors(White&Haring,1980).But the strengthening of any behavior relative to another is not necessarily simple and records of empirically supported treatment options can be interpreted in an over-simplified manner.The current paper attempts to connect various treatment options across behaviors through a common principle-levels of one behavior will tend to increase and levels of another will tend to decrease when the first behavior is made more efficient than the second.The primary objective of the current paper is to articulate a wide variety of variable dimensions available to behavior analysts,teachers,and other professionals responsible for behavior change.In complex environments,many factors are beyond our control and many treatment options are non-viable.The greater the variety of treatment options available,the“larger the analyst’s toolbox”,the greater the chance that viable treatments will be found and that ineffective strategies can be effectively modified before being set aside.One recurring theme is that various forms of response blocking can and should be minimized and replaced with strategies that make more desirable behavior more efficient than less desirable behavior,leading learners to“choose”more desirable behavior.An additional objective of the paper is to reframe the debate about whether it is appropriate to use extinction or punishment,wherein those strategies are frequently interpreted in absolute terms,in relation to decreasing undesirable behaviors,and inevitably result in negative side effects.A more nuanced discussion about extinction and punishment considers the extent to which parametric applications of either might be appropriate to make a less desirable behavior less efficient than a more desirable behavior and includes the potential impact upon increasing desirable behaviors. 展开更多
关键词 Matching Law efficiency consequences perspectives CONSTRUCTIVISM variable dimensions
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Research on Key Stages and Control Strategies of Whole-Process Cost Management in Agency-Built Projects
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作者 Minjie Hu 《Journal of World Architecture》 2025年第2期22-28,共7页
Against the backdrop of the increasingly complex construction market environment,the whole-process cost management of agency-built projects faces issues such as cost overruns and insufficient management efficiency due... Against the backdrop of the increasingly complex construction market environment,the whole-process cost management of agency-built projects faces issues such as cost overruns and insufficient management efficiency due to the numerous stages and high technical requirements involved.This paper focuses on the key stages of whole-process cost management in agency-built projects,including project initiation,design,construction,and completion.It proposes strategies to optimize the cost management process and enhance management efficiency,providing theoretical support and practical guidance for the whole-process cost management under the agency-built model. 展开更多
关键词 Agency-built projects Whole-process cost management Cost control Dynamic management Completion settlement
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