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Integration of Theory and Practice in Medical Morphology Curriculum in Postgraduate Training:A Flipped Classroom and Case-based Learning Exercise 被引量:2
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作者 Xi-min HU Zhi-xin LI +5 位作者 Jing DENG Yang HAN Shuang LU Qi ZHANG Zi-qiang LUO Kun XIONG 《Current Medical Science》 SCIE CAS 2023年第4期741-748,共8页
Objective:The integration of training in theory and practice across the medical education spectrum is being encouraged to increase student understanding and skills in the sciences.This study aimed to determine the dec... Objective:The integration of training in theory and practice across the medical education spectrum is being encouraged to increase student understanding and skills in the sciences.This study aimed to determine the deciding factors that drive students'perceived advantages in class to improve precision education and the teaching model.Methods:A mixed strategy of an existing flipped classroom(FC)and a case-based learning(CBL)model was conducted in a medical morphology curriculum for 575 postgraduate students.The subjective learning evaluation of the individuals(learning time,engagement,study interest and concentration,and professional integration)was collected and analyzed after FC-CBL model learning.Results:The results from the general evaluation showed promising results of the medical morphology in the FC-CBL model.Students felt more engaged by instructors in person and benefited in terms of time-saving,flexible arrangements,and professional improvement.Our study contributed to the FC-CBL model in Research Design in postgraduate training in 4 categories:1)advancing a guideline of precision teaching according to individual characteristics;2)revealing whether a learning background is needed for a Research Design course to guide setting up a preliminary course;3)understanding the perceived advantages and their interfaces;and 4)barriers and/or improvement to implement the FC-CBL model in the Research Design class,such as a richer description of e-learning and hands-on practice.Conclusion:Undertaking a FC-CBL combined model could be a useful addition to pedagogy for medical morphology learning in postgraduate training. 展开更多
关键词 flipped classroom case-based learning medical morphology curriculum research design POSTGRADUATE
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Generalized Szasz Problems in Normal Classes of Algebras
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作者 王尧 牛凤文 《Northeastern Mathematical Journal》 CSCD 2004年第2期225-235,共11页
Let A be a normal class of algebras. In the present paper, we characterize the following four problems for A: for which radical class R, there holds that(1) R(i1∧i2) = R(i1)∧R(i2);(2) R(i1∨i2) = R(i1)∨R(i2);(3) (i... Let A be a normal class of algebras. In the present paper, we characterize the following four problems for A: for which radical class R, there holds that(1) R(i1∧i2) = R(i1)∧R(i2);(2) R(i1∨i2) = R(i1)∨R(i2);(3) (i1∧i2) =i1∧i2;(4) (i1∨i2) = i1∨i2, for arbitrary algebra a∈A and any i1,i2∈La,where j denotes the ideal of a uniquely determined by R(a/j) = j/j? 展开更多
关键词 normal class of algebra LATTICE equivalence relation RADICAL
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NEUMANN PROBLEMS OF A CLASS OF ELLIPTIC EQUATIONS WITH DOUBLY CRITICAL SOBOLEV EXPONENTS 被引量:3
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作者 韩丕功 《Acta Mathematica Scientia》 SCIE CSCD 2004年第4期633-638,共6页
This paper deals with the Neumann problem for a class of semilinear elliptic equations -△u + u =|u|2*-2u+ μ|u|q-2u in Ω, au/ar= |u|(?)*-2u on aΩ, where 2 = 2N/N-2, s=2(N-1)/N-2, 1 <q<2,N(?)3,μ>γ denotes... This paper deals with the Neumann problem for a class of semilinear elliptic equations -△u + u =|u|2*-2u+ μ|u|q-2u in Ω, au/ar= |u|(?)*-2u on aΩ, where 2 = 2N/N-2, s=2(N-1)/N-2, 1 <q<2,N(?)3,μ>γ denotes the unit outward normal to boundary aΩ. By vaxiational method and dual fountain theorem, the existence of infinitely many solutions with negative energy is proved. 展开更多
关键词 Neumann problem semilinear elliptic equation (PS)·c condition critical Sobolev exponent
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COMPUTER COMPUTATION OF THE METHOD OF MULTIPLE SCALES-DIRICHLET PROBLEM FOR A CLASS OF SYSTEM OF NONLINEAR DIFFERENTIAL EQUATIONS
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作者 谢腊兵 江福汝 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2003年第11期1264-1272,共9页
The method of boundary layer with multiple scales and computer algebra were applied to study the asymptotic behavior of solution of boundary value problems for a class of system of nonlinear differential equations . T... The method of boundary layer with multiple scales and computer algebra were applied to study the asymptotic behavior of solution of boundary value problems for a class of system of nonlinear differential equations . The asymptotic expansions of solution were constructed. The remainders were estimated. And an example was analysed. It provides a new foreground for the application of the method of boundary layer with multiple scales . 展开更多
关键词 system of nonlinear differential equation boundary value problem method of boundary layer with multiple scale computer algebra asymptotic solution
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New Approach to Rock Classification Based on Sparse Representations
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作者 Wognin Joseph Vangah Bi G. Théodore Toa +2 位作者 Alico Nango Jerôme Ouattara Sie Alain Clément 《Open Journal of Applied Sciences》 2024年第1期145-158,共14页
In geology, classification and lithological recognition of rocks plays an important role in the area of oil and gas exploration, mineral exploration and geological analysis. In other fields of activity such as constru... In geology, classification and lithological recognition of rocks plays an important role in the area of oil and gas exploration, mineral exploration and geological analysis. In other fields of activity such as construction and decoration, this classification makes sense and fully plays its role. However, this classification is slow, approximate and subjective. Automatic classification curbs this subjectivity and fills this gap by offering methods that reflect human perception. We propose a new approach to rock classification based on direct-view images of rocks. The aim is to take advantage of feature extraction methods to estimate a rock dictionary. In this work, we have developed a classification method obtained by concatenating four (4) K-SVD variants into a single signature. This method is based on the K-SVD algorithm combined with four (4) feature extraction techniques: DCT, Gabor filters, D-ALBPCSF and G-ALBPCSF, resulting in the four (4) variants named K-Gabor, K-DCT, KD-ALBPCSF and KD-ALBPCSF respectively. In this work, we developed a classification method obtained by concatenating four (4) variants of K-SVD. The performance of our method was evaluated on the basis of performance indicators such as accuracy with other 96% success rate. 展开更多
关键词 Rock Recognition DICTIONARY SIGNATURE Color Texture K-SVD Variants KD-ALBPCSF Et KG-ALBPCSF
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ON A NEW CLASS OF FUNCTION SPACES 被引量:1
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作者 丁夏畦 《Chinese Science Bulletin》 SCIE EI CAS 1981年第11期973-976,共4页
In this paper we shall introduce a class of new function spaces. They are generalizations of some Orlicz spaces and Orlicz-Sobolev spaces, and they are derived from the results of the investigation on imbedding relati... In this paper we shall introduce a class of new function spaces. They are generalizations of some Orlicz spaces and Orlicz-Sobolev spaces, and they are derived from the results of the investigation on imbedding relations between some Orlicz-Sobolev spaces. 展开更多
关键词 CLASS notation satis 初云 才人 七子山 otherwise LEMMA BESSEL 江时
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ON THE MINIMUM OF A CLASS OF NONLINEAR FUNCTIONALS
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作者 定光桂 《Chinese Science Bulletin》 SCIE EI CAS 1983年第3期306-309,共4页
In this paper, we will introduce the definition of a class of nonlinear functionals and some examples about it and then offer a theorem of the minimum about a class of nonlinear functionals on the close central ball i... In this paper, we will introduce the definition of a class of nonlinear functionals and some examples about it and then offer a theorem of the minimum about a class of nonlinear functionals on the close central ball in the metric linear space with 'β-degree circular homogeneous' metric. 展开更多
关键词 CLASS CIRCULAR assume SUBSET QUASI mentioned nates finitely 梦夕 ENOUGH
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A CLASS OF COMMUTATIVE RINGS WITH PRIME FORMULAS
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作者 王世强 《Chinese Science Bulletin》 SCIE EI 1983年第4期436-440,共5页
Model theory is usually regarded as a comparatively abstract branch of mathematical logic. In this paper we will record, along the same line as what was done in [1], another one of our trials of finding new applicatio... Model theory is usually regarded as a comparatively abstract branch of mathematical logic. In this paper we will record, along the same line as what was done in [1], another one of our trials of finding new applications of model-theoretic conclusions to other branches of mathematics, Considering certain residue class rings of the ring I of 展开更多
关键词 BRANCHES mathematics INTEGERS CLASS finding conclusions residue record rings STATEMENT
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ON INITIAL VALUE PROBLEM OF A CLASS OF DEGENERATE EQUATION
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作者 郑兴礼 《Chinese Science Bulletin》 SCIE EI CAS 1983年第11期1433-1436,共4页
<正> Ⅰ.INTRODUCTION The initial value problem of degenerate equation as is well-known, has the so-called discrete phenomena in C~∞ If it is discussed in a class of analytic functions, then the initial value pr... <正> Ⅰ.INTRODUCTION The initial value problem of degenerate equation as is well-known, has the so-called discrete phenomena in C~∞ If it is discussed in a class of analytic functions, then the initial value problem has another strange phenomena, that is, the solution of the equation (p≠0) is determined entirely by only one initial value conditiont.This shows that the degenerate equation 展开更多
关键词 DEGENERATE STRANGE ANALYTIC entirely CLASS VANISHING analogous formal uniquely assume
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A CLASS OF PROBABILISTIC LINEAR NORMED SPACES AND RANDOM OPERATORS
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作者 林熙 《Chinese Science Bulletin》 SCIE EI CAS 1983年第10期1295-1298,共4页
The concept of probabilistic metric spaces was introduced by Menger in 1942.Based on the similar idea, the concept of random normed spaces (i. e. probabilistie linear normed spaces) was presented by Serstnev.Since the... The concept of probabilistic metric spaces was introduced by Menger in 1942.Based on the similar idea, the concept of random normed spaces (i. e. probabilistie linear normed spaces) was presented by Serstnev.Since then, Bocsan, Dumitrescu and You Zhaoyong et al. have been working in this field. In this paper, based upon the study of a class of probabilistic linear normed spaces: B-spaces, we study random operators, which can be used as one of new 展开更多
关键词 NORMED operators PROBABILISTIC VALUED CLASS NEIGHBORHOOD UNIQUENESS satis proof briefly
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腹腔镜局部进展期远端胃癌D2根治术标准操作流程:CLASS-01研究共识 被引量:38
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作者 李国新 +1 位作者 季加手 郑民华 《中华胃肠外科杂志》 CAS CSCD 北大核心 2019年第9期807-811,共5页
腹腔镜对比开腹手术治疗局部进展期远端胃癌的前瞻性、多中心、随机对照研究(CLASS-01),为局部进展期胃癌微创外科提供了高级别循证医学证据。结果表明,经验丰富的团队实施腹腔镜远端胃癌D2根治术治疗局部进展期患者是安全、有效的,具... 腹腔镜对比开腹手术治疗局部进展期远端胃癌的前瞻性、多中心、随机对照研究(CLASS-01),为局部进展期胃癌微创外科提供了高级别循证医学证据。结果表明,经验丰富的团队实施腹腔镜远端胃癌D2根治术治疗局部进展期患者是安全、有效的,具有显著的微创优势。这一研究成果引起了学术界的广泛关注。为了在临床实践中正确地认识和科学地应用该研究的成果,本文发布CLASS-01研究共识,以飨读者。内容包括相关定义、手术适应证、器械准备、围手术期处理、手术原则与标准操作流程以及质量控制等关键问题。相关标准操作流程是CLASS-01研究方案撰写时,研究者之间达成的共识,其中的基本原则参考了国际国内权威指南,也充分考虑了我国腹腔镜胃癌外科的实际状况,对我国局部进展期胃癌腹腔镜外科技术的科学发展与合理推广,具有重要的指导意义。 展开更多
关键词 胃肿瘤 局部进展期 D2根治术 远端胃切除术 腹腔镜 规范 共识
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A CLASS OF STRONGLY NONLINEAR SINGULARLY PERTURBED INTERIOR LAYER PROBLEMS 被引量:19
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作者 唐荣荣 《Annals of Differential Equations》 2004年第3期278-282,共5页
In this paper, a class of strongly nonlinear singularly perturbed interior layer problems are considered by the theory of differential inequalities and the corrective theory of interior layer. The existence of solutio... In this paper, a class of strongly nonlinear singularly perturbed interior layer problems are considered by the theory of differential inequalities and the corrective theory of interior layer. The existence of solution is proved and the asymptotic behavior of solution for the boundary value problems are studied. And the satisfying result is obtained. 展开更多
关键词 singular perturbation interior layer problems differential inequality asymptotic behavior
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GLOBAL EXISTENCE FOR A CLASS OF SYSTEMSOF NONLINEAR WAVE EQUATIONS INTHREE SPACE DIMENSIONS
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作者 S.KATAYAMA 《Chinese Annals of Mathematics,Series B》 SCIE CSCD 2004年第4期463-482,共20页
Consider a system of nonlinear wave equations (e)2t-c2i△xui=Fi(u,(e)u,(e)x(e)u) in (0,∞)×(R)3 for i=1,┈,m,where Fi(i=1,┈,m) are smooth functions of degree 2 near the origin of their arguments, and u=(u1,┈,um... Consider a system of nonlinear wave equations (e)2t-c2i△xui=Fi(u,(e)u,(e)x(e)u) in (0,∞)×(R)3 for i=1,┈,m,where Fi(i=1,┈,m) are smooth functions of degree 2 near the origin of their arguments, and u=(u1,┈,um),while (e)u and (e)x(e)u represent the first and (second derivatives of u, respectively. In this paper, the author presents a new class of nonlinearity for which the global existence of small solutions is ensured. For example, global existence of small solutions for((e)2t- c21Δx)u1 = u2((e)tu2) + arbitrary cubic terms,((e)2t - c22Δx)u2=u1((e)tu2) + ((e)tu1)u2 + arbitrary cubic termswill be established, provided that c21 ≠ c22. 展开更多
关键词 波动方程 倍数 处处存在 偏微分方程 非线性
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外泌体传递lncRNA RPL23AP82促进胰腺导管腺癌吉西他滨耐药 被引量:1
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作者 孙运鹏 吴欢欢 +3 位作者 庄磊 陈浩然 徐博 黄侠鸣 《武汉大学学报(医学版)》 2025年第7期850-856,905,共8页
目的:探究外泌体传递lncRNA RPL23AP82促进胰腺导管腺癌(PDAC)吉西他滨(GEM)耐药。方法:(1)构建lncRNA RPL23AP82过表达载体并转染至SW1990细胞中后用GEM进行干扰、分组,对比细胞增殖活性、细胞凋亡。(2)SW1990细胞系转染shRNA‑RPL23AP8... 目的:探究外泌体传递lncRNA RPL23AP82促进胰腺导管腺癌(PDAC)吉西他滨(GEM)耐药。方法:(1)构建lncRNA RPL23AP82过表达载体并转染至SW1990细胞中后用GEM进行干扰、分组,对比细胞增殖活性、细胞凋亡。(2)SW1990细胞系转染shRNA‑RPL23AP82并分组,对比miR‑129、PFTK1 mRNA与PFTK1蛋白表达;SW1990细胞系转染miR‑129 mimics或miR‑129 inhibitor,对比PFTK1 mRNA、PFTK1蛋白表达。(3)SW1990细胞系诱导构建GEM耐受型PDAC细胞(SW1990‑GR)并提取外泌体与亲本细胞孵育,分别根据加入GEM、转染sh‑NC或sh‑RPL23AP82、转染sh‑NC或外泌体抑制剂GW4869,对比lncRNA RPL23AP82表达、GEM敏感性变化、细胞凋亡、细胞增殖活性。结果:(1)对比LV‑NC组,LV‑RPL23AP82组RPL23AP82相对表达量、细胞增殖活性更高且细胞凋亡更低,LV‑NC+GEM组细胞增殖活性更低,LV‑RPL23AP82+GEM组细胞增殖活性低于LV‑RPL23AP82组(均P<0.05)。(2)sh‑RPL23AP82组中RPL23AP82相对表达量低于sh‑NC组,对比sh‑NC组,sh‑RPL23AP82组miR‑129表达升高且PFTK1 mRNA、PFTK1蛋白均下降(均P<0.05);对比NC mimics组,miR‑129 mimics组miR‑129表达升高且miR‑129 inhibitor组miR‑129表达降低,miR‑129 mimics组PFTK1 mRNA和PFTK1蛋白水平降低,而miR‑129 inhibitor组PFTK1 mRNA和PFTK1蛋白水平升高(均P<0.05)。(3)SW1990‑GR组lncRNA RPL23AP82表达、SW1990‑GR组细胞增殖活性升高,对比SW1990‑GR组,SW1990‑GR+GEM组细胞增殖活性下调且细胞凋亡升高,耐药细胞SW1990‑GR与GEM共干扰后细胞凋亡下降(均P<0.05);敲低RPL23AP82后细胞增殖活性下调;GW4869抑制外泌体分泌后GW4869降低,抑制细胞增殖活性;抑制剂GW4869处理细胞增殖活性下降,细胞凋亡上升(均P<0.05)。结论:外泌体上调lncRNA RPL23AP82可降低miR‑129表达并通过刺激PFTK1表达促进吉西他滨耐药。 展开更多
关键词 胰腺导管癌 细胞周期蛋白依赖性激酶14 长链非编码RNA RPL23AP82 微小非编码RNA‑129 细胞增殖 细胞凋亡 吉西他滨 耐药
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ON THE RELIABILITY BOUNDS IN κ-HNBUE AND κ-HNWUE CLASSES
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作者 程侃 何宗福 胡逸民 《Acta Mathematicae Applicatae Sinica》 SCIE CSCD 1991年第1期38-52,共15页
k-HNBUE class and its dual were introduced by Basu and Ebrahimi [2]. In this paper wegive a generalized definition, and discuss their reliability bounds based on the known mean.
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A CLASS OF PP L-STATISTICS FOR TESTS
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作者 施沛德 李国英 《Acta Mathematicae Applicatae Sinica》 SCIE CSCD 1992年第1期27-44,共18页
Applying projection pursuit (PP) techniques, this paper takes L-statistics as projectionindices to construct a class of statistics for multivariate tests. The asymptotic distributions ofthe test statistics under null ... Applying projection pursuit (PP) techniques, this paper takes L-statistics as projectionindices to construct a class of statistics for multivariate tests. The asymptotic distributions ofthe test statistics under null hypothesis are derived theoretically. Some simple applications tolocation and dispersion problems are given. 展开更多
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一元函数极值充分条件的推广
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作者 朱彩兰 张红锋 纪勤玮 《红河学院学报》 2025年第5期142-144,共3页
通过对一元函数极值的第二充分条件进行推广,从而得出满足(n-1)阶导数为零,而n阶导数不为零的点是否为函数的极值点的判别方法,并举例验证.
关键词 函数极值 极值点 充分条件
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基于科教融合理念的药剂学综合实验设计与实践
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作者 沈奇英 郑威 沈嘉炜 《广东化工》 2025年第8期167-169,共3页
目的:将科学研究与实验教学相结合,对药剂学综合实验进行了改革尝试。方法:该实验结合新型纳米制剂的相关技术:脂质体薄膜-pH梯度载药方法、表征方法,并优化了工艺,同时引入细胞培养、细胞耐药及噻唑蓝比色法检测细胞活性的相关知识。结... 目的:将科学研究与实验教学相结合,对药剂学综合实验进行了改革尝试。方法:该实验结合新型纳米制剂的相关技术:脂质体薄膜-pH梯度载药方法、表征方法,并优化了工艺,同时引入细胞培养、细胞耐药及噻唑蓝比色法检测细胞活性的相关知识。结果:脂质体的制备、理化性质和体外细胞评价等领域的相互融合,促进科研与教学相互转化,实现了科研反哺教学,提高学习药剂学的兴趣的同时巩固教学中的相关重点。结论:有望为药剂学课程教学真正达到科教融合奠定基础。 展开更多
关键词 科教融合 药剂学 综合实验 纳米制剂 教学改革
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多特征融合的油气勘探领域命名实体识别与应用
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作者 袁满 赵兴雨 +1 位作者 袁靖舒 马茁然 《吉林大学学报(信息科学版)》 2025年第2期401-411,共11页
针对现有命名实体识别方法在识别油气勘探文本中涉及多元素组合的实体以及嵌套实体时存在一定局限性的问题,提出了一种多特征融合的BERT-CNN-BiGRU-Attention-CRF(Bidirectional Encoder Representations from Transformers-Convolution... 针对现有命名实体识别方法在识别油气勘探文本中涉及多元素组合的实体以及嵌套实体时存在一定局限性的问题,提出了一种多特征融合的BERT-CNN-BiGRU-Attention-CRF(Bidirectional Encoder Representations from Transformers-Convolutional Neural Network-Bidirectional Gated Recurrent Unit-Attention-Conditional Random Field)命名实体识别方法。模型利用BERT的语义提取能力获取句子具有全局特征的字向量;并利用CNN局部特征捕获能力消除了BERT字向量的局限性得到词语字符级向量;通过自建油气勘探领域词典,使用双向最大长度匹配方法获取了词典特征向量。将这3种向量拼接作为BiGRU-Attention-CRF模型的输入。实验结果表明,在自主构建的小规模油气勘探领域数据集上,模型的F_(1)值为91.10%,相较于其他主流的命名实体识别方法,该模型具有更好的识别性能,并为油气勘探领域知识图谱构建提供了有利帮助。 展开更多
关键词 命名实体识别 油气勘探 知识图谱 BERT预训练模型 卷积神经网络 词典特征
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1990—2021年中国老年人群抑郁症的疾病负担情况分析及预测 被引量:1
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作者 汪洋帆 胡银环 +3 位作者 路少玉 刘莎 冯显东 王慧 《中国慢性病预防与控制》 北大核心 2025年第3期178-184,共7页
目的 了解1990—2021年中国老年人群抑郁症疾病负担及其变化情况,并对2020—2044年的变化趋势进行预测,为抑郁症相关防控策略的制定提供依据。方法 数据来源于2021年全球疾病负担(GBD2021)数据库,提取1990—2021年中国老年人群抑郁症的... 目的 了解1990—2021年中国老年人群抑郁症疾病负担及其变化情况,并对2020—2044年的变化趋势进行预测,为抑郁症相关防控策略的制定提供依据。方法 数据来源于2021年全球疾病负担(GBD2021)数据库,提取1990—2021年中国老年人群抑郁症的疾病负担数据。采用Excel 2021描述发病例数、标化发病率、伤残调整寿命年(DALY)、标化DALY率、变化率等指标。应用Joinpoint 5.2.0软件进行回归分析,计算1990—2021年抑郁症疾病负担变化趋势。采用R 4.4.1软件Nordpred包进行年龄-时期-队列模型拟合以预测中国2020—2044年抑郁症的未来疾病负担情况。结果 2021年中国老年人群抑郁症标化发病率为5 654.72/10万、标化DALY率为967.29/10万,相较1990年分别增长了25.98%和18.76%。分性别分析显示,1990—2021年女性抑郁症的发病例数、标化发病率、DALY和标化DALY率均高于男性,而男性抑郁症的发病例数、标化发病率和DALY 3项的增幅均高于女性。分年龄分析显示,2021年除≥95岁年龄组外,60~94岁7个年龄组的发病率和DALY率均较1990年升高,其中60~64、65~69、70~74岁年龄组上升显著,发病率的变化率依次为33.25%、29.86%、27.29%,DALY率的变化率依次为21.97%、20.54%、19.63%。Joinpoint回归分析显示,1990—2021年中国老年人群抑郁症的标化发病率和标化DALY率平均每年分别上升0.739%(95%CI:0.622%~0.856%)和0.575%(95%CI:0.454%~0.696%),上升趋势有统计学意义(P<0.05)。预测模型结果显示,2020—2044年中国老年人群抑郁症的发病例数、DALY、标化发病率、标化DALY率均呈明显上升趋势,将由2020年的15 416 824例、2 606 457人年、5 936.98/10万和994.58/10万分别上升至2044年的31 094 393例、4 620 946人年、6 707.67/10万和1 016.13/10万。结论 1990—2021年,中国老年人群的抑郁症疾病负担显著上升,且未来趋势依旧严峻,亟须强化对老年人群的心理健康教育及服务体系构建,重点关注60~74岁老年人群,并加速推进抑郁症的早筛、早诊、早治工作。 展开更多
关键词 抑郁症 疾病负担 老年人口 预测
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