Preterm birth and suboptimal fetal growth remain significant perinatal challenges worldwide.Recent data indicate that China's perinatal profile has improved due to reductions in preterm birth rates.However,the cou...Preterm birth and suboptimal fetal growth remain significant perinatal challenges worldwide.Recent data indicate that China's perinatal profile has improved due to reductions in preterm birth rates.However,the country has a 6.5%prevalence of small-for-gestational-age(SGA),ranking fifth globally in total SGA birth numbers^([1,2]).展开更多
BACKGROUND Cervical cancer is the second leading cause of death in women worldwide,second only to breast cancer.Around 80%of women have been infected with human papillomavirus(HPV)in their lifetime.Early screening and...BACKGROUND Cervical cancer is the second leading cause of death in women worldwide,second only to breast cancer.Around 80%of women have been infected with human papillomavirus(HPV)in their lifetime.Early screening and treatment are effective means of preventing cervical cancer,but due to economic reasons,many parts of the world do not have free screening programs to protect women’s health.AIM To increase HPV cervical cancer screening in Changsha and reduce the incidence of cervical cancer.METHODS Cervical cancer screening included gynecological examination,vaginal secretion examination and HPV high-risk typing testing.Cervical cytology examination(ThinPrep cytology test)was performed for individuals who test positive for HPV types other than 16 and 18.Vaginal colposcopy examination was performed for HPV16 and 18 positive individuals,as well as for those who were positive for ThinPrep cytology test.If the results of vaginal colposcopy examination were abnormal,histopathological examination was performed.We conducted a cost-benefit analysis after 4 years.RESULTS From 2019 to 2022,523437 women aged 35-64 years in Changsha city were screened and 73313 were positive,with a 14%positive rate.The detection rate of precancerous lesions of cervical cancer was 0.6%and the detection rate of cervical cancer was 0.037%.Among 311212 patients who underwent two cancers examinations,the incidence rate was reduced by more than half in the second examination.The average screening cost per woman was 120 RMB.The average cost of detecting early cases was 10619 RMB,with an early detection cost coefficient of 0.083.CONCLUSION Our screening strategy was effective and cost-effective,making it valuable for early diagnosis and treatment of cervical cancer.It is worth promoting in economically limited areas.展开更多
The coordinated development of human settlement environment and economy is of vital significance to urban sustainable development and urban ecosystem health. Urban human settlement and economic systems exist in urban ...The coordinated development of human settlement environment and economy is of vital significance to urban sustainable development and urban ecosystem health. Urban human settlement and economic systems exist in urban ecosystems, which are a structural complexity. Therefore the research is being challenged by some uncertain factors between human settlements and economic systems. However most of the researches were focused on its determinate objective aspects and qualitative analyses while less concern on the quanti- tative evaluation of coordinated development of urban human settlement environment and economy, especially little on its uncertain aspect. At present, the urgent task is to study the coordinated development of urban settlement environment and economy in terms of the effect of uncertainty. This study analyzed the uncertain characteristics, which would be confronted at different stages, such as confirming the index categories, their bound values, and their construction rate, etc. According to the actual urban conditions, many construction principles based on uncertainties are put forward and an indicating system for human settlement and economic evaluation is established. Moreover, the application of fuzzy mathematics presents a new method and a calculation model for the comprehensive assessment of the coordinated development of urban human settlement environment and economy. The application of the method and model in Changsha city of China showed that the assessment results can reflect not only the overall coordination degree of the city, but also the mode of interactive mechanism between urban economic system and human settlement environment.展开更多
In view of the lack of comprehensive evaluation and analysis from the combination of natural and human multi-dimensional factors,the urban surface temperature patterns of Changsha in 2000,2009 and 2016 are retrieved b...In view of the lack of comprehensive evaluation and analysis from the combination of natural and human multi-dimensional factors,the urban surface temperature patterns of Changsha in 2000,2009 and 2016 are retrieved based on multi-source spatial data(Landsat 5 and Landsat 8 satellite image data,POI spatial big data,digital elevation model,etc.),and 12 natural and human factors closely related to urban thermal environment are quickly obtained.The standard deviation ellipse and spatial principal component analysis(PCA)methods are used to analyze the effect of urban human residential thermal environment and its influencing factors.The results showed that the heat island area increased by 547 km~2 and the maximum surface temperature difference reached 10.1℃during the period 2000–2016.The spatial distribution of urban heat island was mainly concentrated in urban built-up areas,such as industrial and commercial agglomerations and densely populated urban centers.The spatial distribution pattern of heat island is gradually decreasing from the urban center to the suburbs.There were multiple high-temperature centers,such as Wuyi square business circle,Xingsha economic and technological development zone in Changsha County,Wangcheng industrial zone,Yuelu industrial agglomeration,and Tianxin industrial zone.From 2000 to 2016,the main axis of spatial development of heat island remained in the northeast-southwest direction.The center of gravity of heat island shifted 2.7 km to the southwest with the deflection angle of 54.9°in 2000–2009.The center of gravity of heat island shifted to the northeast by 4.8 km with the deflection angle of 60.9°in 2009–2016.On the whole,the change of spatial pattern of thermal environment in Changsha was related to the change of urban construction intensity.Through the PCA method,it was concluded that landscape pattern,urban construction intensity and topographic landforms were the main factors affecting the spatial pattern of urban thermal environment of Changsha.The promotion effect of human factors on the formation of heat island effect was obviously greater than that of natural factors.The temperature would rise by 0.293℃under the synthetic effect of human and natural factors.Due to the complexity of factors influencing the urban thermal environment of human settlements,the utilization of multi-source data could help to reveal the spatial pattern and evolution law of urban thermal environment,deepen the understanding of the causes of urban heat island effect,and clarify the correlation between human and natural factors,so as to provide scientific supports for the improvement of the quality of urban human settlements.展开更多
This research systematically analyses land-use map of Changsha city in different periods of time. The spatial form and structural evolution was analysed by studying indices such as city land-use structure proportion, ...This research systematically analyses land-use map of Changsha city in different periods of time. The spatial form and structural evolution was analysed by studying indices such as city land-use structure proportion, expansion intensity, economic flexibility, population flexibility, changing compactness index and so on. The dynamic mechanism of urban land expansion has been discussed by integrating the regional social economy development situation and many aspects such as the physiographical surrounding, population and economic development, traffic infrastructure, planning and regional development tactic and system innovation. The research indicates that the urban land expansion speed and intensity have steadily increased in Changsha from 1949 to 2004. The expansion form has been from a single external expansion to a combination form of external and internal expansion, from a circular or linear continuous form to a blocky or agglomeration shape. Overall, the urban land expansion of Changsha city is a phasic, diversified and complex process. And no matter what the stage is, it is an organic system containing multiple speed, pattern and shape, which are driven by multiple impetuses. The dominant feature at different stages was highlighted because of the balance and fluctuation between different forces, and the existing urban land border and shape have resulted from the joint efforts of these phasic forces.展开更多
Although traditional urban expansion simulation models can simulate dynamic features, these models fail to address complex changes produced by different agents＇ behaviors. The paper has built up a set of spatial-temp...Although traditional urban expansion simulation models can simulate dynamic features, these models fail to address complex changes produced by different agents＇ behaviors. The paper has built up a set of spatial-temporal land resource allocation rules and developed a dynamic urban expansion model based on a multi-agent system, which can simulate the interaction among different agents, such as residents, peasants, and governments. This model is applied to simulate urban expansion process taking Changsha City, in China as a study area. The results show that this model can not only reflect basic characteristics of urban expansion, but also help explain the reasons for urban expansion process and understand the effect of agents＇ behavior on the expansion process, and provide insights into the causing factors behind the expansion. In addition, in contrast to simulation results with land use classification map from remote sensing images, the precision of the simulation reached over 68% with higher precision than cellular automata model according to the cell-by-cell comparison. The results suggest that the model can help to provide land use decision making support to government and urban planners.展开更多
The research purpose is to accurately reveal the temporal and spatial law of the urban expansion of Changsha-Zhuzhou-Xiangtan, one of the seven major urban agglomeration areas in China, and provide decision-making bas...The research purpose is to accurately reveal the temporal and spatial law of the urban expansion of Changsha-Zhuzhou-Xiangtan, one of the seven major urban agglomeration areas in China, and provide decision-making basis for the future urban construction land layout and regional development policy-making. Based on the night lighting data (DMSP/OLS), this paper extracts the boundary of the urban construction land of Changsha-Zhuzhou-Xiangtan urban agglomeration from 1993 to 2017, and quantitatively studies the spatial and temporal characteristics of the expansion of the metropolitan area in the past 25 years according to the methods of spatial expansion analysis, center of gravity migration measurement, landscape pattern index, spatial autocorrelation, etc. The results show that: 1) it is scientific and feasible to extract urban agglomeration construction land by the method of auxiliary data comparison for the study of urban expansion;2) the expansion of regional space in Changsha-Zhuzhou-Xiangtan metropolitan area shows a trend of “weakening first and strengthening later”. The construction land keeps increasing, and the expansion form gradually changes from extensive type to intensive type;3) the center of gravity of the metropolitan area fluctuated and repeated in part during the past 25 years, but it was always located in the municipal district of Changsha city. The eastern region, mainly Changsha city, was still the core area of urban agglomeration expansion;4) strengthening the territorial space protection and control of ecological green core in the metropolitan area is a key measure for the high-quality development of urban agglomeration.展开更多
By analyzing the status quo of land resources in " green heart" area of Changsha-Zhuzhou-Xiangtan urban agglomeration,and problems existing in land management,this article puts forward some countermeasures a...By analyzing the status quo of land resources in " green heart" area of Changsha-Zhuzhou-Xiangtan urban agglomeration,and problems existing in land management,this article puts forward some countermeasures and proposals as follows:establish new land management mechanism in " green heart" area;based on land planning," green heart" overall planning and policies and regulations,manage land and promote the protection of urban ecological environment.展开更多
[ Objective] The research aimed to study relationship between summer electricity and meteorological factors. [ Method] Electrical load characteristics in Changsha during 2007 -2010 were analyzed. Correlation analysis ...[ Objective] The research aimed to study relationship between summer electricity and meteorological factors. [ Method] Electrical load characteristics in Changsha during 2007 -2010 were analyzed. Correlation analysis between electrical load and meteorological factors （daily average temperature, the maximum temperature, the minimum temperature, rainfall, wind, relative humidity and atmospheric pressure） during July - September of 2007 -2010 was conducted. [ Result] Changes of the meteorological factors could directly affect electrical load, and temperature was the first influence factor. Prediction model of summer electrical load in Changsha was established by regression analysis method.[ Conclusion] The research could provide reference basis for prediction of the electrical load in Changsha.展开更多
The Changsha-Xiangtan-Zhuzhou City Group is a heavy industrial district and accepted as the serious pollution area in the Xiangjiang River basin.In this study,7 metals(Pb,Hg,Cd,As,Zn,Cu and Se)and the river water qual...The Changsha-Xiangtan-Zhuzhou City Group is a heavy industrial district and accepted as the serious pollution area in the Xiangjiang River basin.In this study,7 metals(Pb,Hg,Cd,As,Zn,Cu and Se)and the river water quality parameters including pH,dissolved oxygen(DO),Escherichia coli(E.coli),potassium permanganate index(CODMn),dichromate oxidizability(CODCr),five-day biochemical oxygen demand(BOD5),ammonia nitrogen(NH4+-N),total nitrogen(TN),total phosphorus(TP)and fluoride(F)in 18 sampling sites of the Changsha-Xiangtan-Zhuzhou section are monthly monitored in 2016,which is the year to step into the second stage of the“Xiangjiang River Heavy Metal Pollution Control Implementation Plan”.It is found that E.coli,TN and TP are the main pollutants in the Changsha-Zhuzhou-Xiangtan section,and the pollution of heavy metal is not serious but As with potential risk to local people especially children should be concerned.In addition,Xiangtan city is mainly featured with heavy metal pollution,while Zhuzhou and Changsha city are both featured with other pollutants from municipal domestic sewage.展开更多
The aim of the study was to develop an index to assess the environmental risk of P loss potential in vegetable soils with chronic difference of plantation in the suburbs of Changsha, Hunan Province, China. Chemical me...The aim of the study was to develop an index to assess the environmental risk of P loss potential in vegetable soils with chronic difference of plantation in the suburbs of Changsha, Hunan Province, China. Chemical methodology was used to study soil phosphorus status and the relationships between available P in soil and potential soil leaching P. The results showed that there was a significant linear relationship between Olsen P and CaC12-P or P concentration in soil solution. Olsen P increased sharply when either CaCI2-P or P concentration in soil solution reached a certain level. It was confirmed that 80 mg kg-t of Olsen P was the critical value of soil P leaching in the vegetable soils. P leaching probability over the critical was assessed by GIS and indicator Kriging and four secondary risks of phosphorus leaching loss were defined. In the area with vegetable cropping for over 30 yr （Chenjiadu） and 10-15 planting years （Huangxingzhen）, the indices of phosphorus leaching loss risk were 3 and 2.93, respectively. These two areas belonged to strong secondary of risk of phosphate leaching loss. In the new vegetable planting field less than 2 yr （Ningxiang）, the index was 0.06, which had almost no risk of phosphorus leaching. In vegetable soils in the suburban region of Changsha, the phosphorus leaching peotential is high and the phosphorus leaching loss is related to chronic length of vegetable cropping.展开更多
Using the system dynamics simulation software Vensim PLE, we built a model to simulate the development of resilient human settlement in Changsha. This model includes five subsystems: living, economy, society, ecology ...Using the system dynamics simulation software Vensim PLE, we built a model to simulate the development of resilient human settlement in Changsha. This model includes five subsystems: living, economy, society, ecology and engineering. The model simulates various scenarios, based on different parameter settings to predict the trend of human settlement from 2019–2040 in Changsha. It puts forward four development programs under different simulation scenarios. The results show that the current system of human settling lacks self-regulation and feedback, where simple increases in the economy and urbanization cannot drive the internal system to progress positively. In contrast, the resilient human settlement program is more reasonable and scientific, up to the year 2040, the production, living and ecological environment of residents will be markedly improved in terms of per capita disposable income, per capita floor space and medical insurance coverage;these will increase by 98.9%, 39.7%, and 170.7%, respectively. This system of developing resilient human settlement provides feedback according to the internal relation loops and thus drives itself to adjust and recover, achieving harmonious and sustainable development. In the forthcoming development, we should take the initiative to optimize economic development and upgrade industrial structures, establish emergency plans and response mechanisms to enhance human quality of life.展开更多
The highway construction inevitably may cause certain influence to the cultural heritage and the natural environment along the route, particularly in design stage; if the route selection is unreasonable, it will certa...The highway construction inevitably may cause certain influence to the cultural heritage and the natural environment along the route, particularly in design stage; if the route selection is unreasonable, it will certainly impact the natural resource seriously along the route. On the contrary, good design can reasonably develop, use, protect and promote the value of cultural heritage and natural environment. Changsha to Jishou （Chang-Ji） freeway is one section of Changsha to Chongqing freeway, which is one of the eight big west channels as planned in China; two cities of Changde and Huaihua and one autonomous region of Xianxi in western Hunan province, along which the cultural heritage and the natural resource are rich, and the natural landscape is exquisite. This paper investigates and analyzes the natural resources along the route of Chang-Ji freeway, puts forward some protection design evaluation indexes for mountain area freeway by the thought of context sensitive design. At last, the paper introduces the effect of applying the indexes to select route of Chang-Ji freeway.展开更多
Background:Xenotransplantation is a potential way to reduce the shortage of the needed organ grafts for the end-stage disease.Immune rejection,physiological incompatibility and bio-safety are the most critical issues....Background:Xenotransplantation is a potential way to reduce the shortage of the needed organ grafts for the end-stage disease.Immune rejection,physiological incompatibility and bio-safety are the most critical issues.Methods:To ensure the safety and efficacy of gene editing,second-and thirdgeneration sequencing technologies have allowed us to obtain a clearer genetic background of donor pigs for xenotransplantation.Based on the Changsha Communiqué,the local DPF-excluded lists and DPF donor facility were established in Changsha,China.A pig-to-human islet clinical trial was conducted and overseen by the respective Chinese governmental agency.Results:The DPF standards for pig husbandry eliminated specific pathogens in donor pigs.We have established a PERV-C free,genetic information clean,DPF donor for xenotransplantation.A clinical trial of ten adult patients(9M:1F)with type 1 diabetes who received DPF porcine islet xenotransplantation via the portal vein were performed.Clinical accepted immunosuppressant drugs and autologous Treg were used for controlling immune rejection.No cross-species infection events occurred in this trial,and importantly,no cross-species transmission of PERV was found.Conclusions:Xenotransplantation is a pioneer study and safety is the most important issue.The fundamental principles for establishing xenotransplantation donor pigs should follow the Changsha Communiqué(2008),the second WHO consultation,and the 2018 Changsha Communiquéwhich would finally help reducing the risks of xenotransplantation.展开更多
Using detection data with high space-time resolution from the wind profile radar and millimeter wave cloud radar of Changsha station,and combining observation data of ground automatic station,heavy precipitation proce...Using detection data with high space-time resolution from the wind profile radar and millimeter wave cloud radar of Changsha station,and combining observation data of ground automatic station,heavy precipitation process in Changsha area from June 29 to July 1,2017 was analyzed.The results showed that the atmospheric temperature advection was calculated by inversion of wind profile radar data of boundary layer,and it could intuitively analyze changes of atmospheric temperature advection before and after precipitation process.The variation characteristics of intensity,thickness and height of warm and cold advection in the upper and lower levels were highly related to the evolution of the precipitation process.The millimeter wave cloud radar can better reflect the vertical structure and evolution of the cloud over the observatory,and had certain indications for the structure characteristics of cloud before the starting of precipitation.When the strong reflectivity started to approach the ground,it also meant that heavy precipitation began to appear.展开更多
Using NCEP reanalysis data,high-altitude and ground observation data,numerical model data,satellite and radar data,formation cause and forecast deviation of an extreme rainstorm process in Changsha urban area at night...Using NCEP reanalysis data,high-altitude and ground observation data,numerical model data,satellite and radar data,formation cause and forecast deviation of an extreme rainstorm process in Changsha urban area at night on June 9,2020 were analyzed.The results showed that(1)the extreme rainstorm process developed near the surface convergence line,with strong localization,short duration and large hourly rainfall intensity.(2)Under the high temperature and high humidity environment,the low-level cold advection and the hot low-pressure system interacted,and the potential con-vective unstable energy was released,and a strong convective weather was formed.(3)The convergence of water vapor in the lower layer and the strong upward movement provided sufficient water vapor for the rainstorm.The low-centroid thunderstorm was the main reason for the extreme rainstorm.(4)The forecast deviation of the numerical model to the low-level shear line and the mesoscale convergence line was an important reason for the forecast deviation of the heavy rainfall area.展开更多
This paper designed the index system for the evaluation of landscape health influence factors of Yanghu Wetland Park from tourists’ perspective,applied the principal component method to extract 19 indexes of 5 public...This paper designed the index system for the evaluation of landscape health influence factors of Yanghu Wetland Park from tourists’ perspective,applied the principal component method to extract 19 indexes of 5 public factors,i.e.policy system,ecological environment,functional management,landscape facility,tourists’ behavior,to analyze the influence factors for the landscape health of national wetland parks.The results showed that tourists’ evaluation varied greatly on the significance of 19 indexes and their satisfaction in the influence factor system of landscape health,then used IPA modified model to classify the factors influencing landscape health of Yanghu Wetland Park into 4 categories,defined the orientation of the 19 indexes in the 4 categories,and proposed the corresponding landscape health optimization strategies based on the analysis results of IPA modified model.展开更多
Objective:the positioning of secondary hospitals in the community rehabilitation work system and the status of community medical rehabilitation ser-vices for the disabled in Changsha were clarified through investigati...Objective:the positioning of secondary hospitals in the community rehabilitation work system and the status of community medical rehabilitation ser-vices for the disabled in Changsha were clarified through investigation and study of the 2019 income of a second-ary general hospital in Changsha.Suggestions from var-ious parties were integrated to provide feasible ideas for expanding the role of secondary hospitals in community rehabilitation.Methods:the 2019 income of a secondary general hospital in Changsha was statistically analyzed,a community rehabilitation questionnaire was designed,and a field survey was carried out focusing on 19 issues including rehabilitation service items,rehabilitation facil-ities and equipment,and the satisfaction of rehabilitation practitioners.Results:in the total hospitalization expenses of a secondary general hospital in Changsha city in 2019,rehabilitation physiotherapy expenses accounted for 7%,and drug treatment expenses accounted for 25%.In addi-tion,in the survey of community rehabilitation service sat-isfaction for the disabled,the difference between the very dissatisfied and very satisfied groups was statistically sig-nificant(P<0.05).Conclusion:taking a secondary gener-al hospital in Changsha city as an example,the treatment methods in secondary general hospitals are still dominated by traditional drug therapy,and the disabled are not sat-isfied with community rehabilitation services.Therefore,rehabilitation treatment projects to meet the rehabilitation needs of the disabled should be promoted in hospitals.展开更多
A statistical analysis on the simultaneous observation data of the temperature inside and outside the themometer shelter in Changsha during summer of 2011 and 2012 was carried out. The results show that the temperatur...A statistical analysis on the simultaneous observation data of the temperature inside and outside the themometer shelter in Changsha during summer of 2011 and 2012 was carried out. The results show that the temperature outside the themometer shelter is higher（ lower） than that inside the themometer shelter in the daytime（ nighttime）. However,there exists a similar variation trend for the average temperature and the extremely maximum temperature inside and outside the themometer shelter in summer. The average temperature and the extremely maximum temperature outside the themometer shelter are higher than that inside the themometer shelter. Furthermore,there exists a difference between the temperatures inside and outside the themometer shelter during different weather conditions. The difference of average temperature reaches 1. 2 ℃ in rainy day,2. 8 ℃ in cloudy day and 3. 1 ℃ in sunny day,and the extremely maximum temperature difference reaches 6. 4 ℃. Especially for the days of high temperature ≥35 ℃,there is 61 high temperature days inside the themometer shelter,while there is 125 high temperature days inside the themometer shelter during 2011- 2012. Furthermore,the extremely maximum temperatures inside and outside the themometer shelter are 38. 9 and42. 0 ℃ respectively. Rainfall and showery rain are the most effective ways to relieve the high temperature in summer. Therefore,the difference between the temperatures inside and outside the themometer shelter should be taken into account in the high temperature forecast and public meteorological service.展开更多
The balanced development of the elementary education sector has been a long goal pursued by the education departments of various places, and is also an outcome expected by the people. Based on a study of the equilibri...The balanced development of the elementary education sector has been a long goal pursued by the education departments of various places, and is also an outcome expected by the people. Based on a study of the equilibrium of the spatial distribution of the capacity saturation models of all the primary schools in Changsha’s (China) five core districts, the results show that the overall geographical distribution of the primary schools in Changsha is relatively balanced, based on the natural characteristics of Changsha, such as human geography, and the moderate gradient between the central urban area and the primary schools in the suburbs and outer suburbs. Then the Theil index model was introduced, and the results of the model analysis show that the differences between elementary schools in Changsha urban area are relatively small, and the main differences originate from between districts rather than within districts, and subtle differences among regions mainly reflect in the teacher strength.展开更多
基金funded by the Natural Science Foundation of Hunan Province(grant number 2024JJ5283 to XH)。
文摘Preterm birth and suboptimal fetal growth remain significant perinatal challenges worldwide.Recent data indicate that China's perinatal profile has improved due to reductions in preterm birth rates.However,the country has a 6.5%prevalence of small-for-gestational-age(SGA),ranking fifth globally in total SGA birth numbers^([1,2]).
文摘BACKGROUND Cervical cancer is the second leading cause of death in women worldwide,second only to breast cancer.Around 80%of women have been infected with human papillomavirus(HPV)in their lifetime.Early screening and treatment are effective means of preventing cervical cancer,but due to economic reasons,many parts of the world do not have free screening programs to protect women’s health.AIM To increase HPV cervical cancer screening in Changsha and reduce the incidence of cervical cancer.METHODS Cervical cancer screening included gynecological examination,vaginal secretion examination and HPV high-risk typing testing.Cervical cytology examination(ThinPrep cytology test)was performed for individuals who test positive for HPV types other than 16 and 18.Vaginal colposcopy examination was performed for HPV16 and 18 positive individuals,as well as for those who were positive for ThinPrep cytology test.If the results of vaginal colposcopy examination were abnormal,histopathological examination was performed.We conducted a cost-benefit analysis after 4 years.RESULTS From 2019 to 2022,523437 women aged 35-64 years in Changsha city were screened and 73313 were positive,with a 14%positive rate.The detection rate of precancerous lesions of cervical cancer was 0.6%and the detection rate of cervical cancer was 0.037%.Among 311212 patients who underwent two cancers examinations,the incidence rate was reduced by more than half in the second examination.The average screening cost per woman was 120 RMB.The average cost of detecting early cases was 10619 RMB,with an early detection cost coefficient of 0.083.CONCLUSION Our screening strategy was effective and cost-effective,making it valuable for early diagnosis and treatment of cervical cancer.It is worth promoting in economically limited areas.
基金Humanities and Social Science Foundation of Ministry of Education of PRC, No.11YJCZH201 Natural Science Foundation of Hunan Province, No.10JJ5017+1 种基金 Social Science Foundation of Hunan Province, No.2010JD19 No.09YBA003
文摘The coordinated development of human settlement environment and economy is of vital significance to urban sustainable development and urban ecosystem health. Urban human settlement and economic systems exist in urban ecosystems, which are a structural complexity. Therefore the research is being challenged by some uncertain factors between human settlements and economic systems. However most of the researches were focused on its determinate objective aspects and qualitative analyses while less concern on the quanti- tative evaluation of coordinated development of urban human settlement environment and economy, especially little on its uncertain aspect. At present, the urgent task is to study the coordinated development of urban settlement environment and economy in terms of the effect of uncertainty. This study analyzed the uncertain characteristics, which would be confronted at different stages, such as confirming the index categories, their bound values, and their construction rate, etc. According to the actual urban conditions, many construction principles based on uncertainties are put forward and an indicating system for human settlement and economic evaluation is established. Moreover, the application of fuzzy mathematics presents a new method and a calculation model for the comprehensive assessment of the coordinated development of urban human settlement environment and economy. The application of the method and model in Changsha city of China showed that the assessment results can reflect not only the overall coordination degree of the city, but also the mode of interactive mechanism between urban economic system and human settlement environment.
基金National Social Science Foundation of China,No.15BJY051Open Topic of Hunan Key Laboratory of Land Resources Evaluation and Utilization,No.SYS-ZX-202002Research Project of Appraisement Committee of Social Sciences Research Achievements of Hunan Province,No.XSP18ZDI031。
文摘In view of the lack of comprehensive evaluation and analysis from the combination of natural and human multi-dimensional factors,the urban surface temperature patterns of Changsha in 2000,2009 and 2016 are retrieved based on multi-source spatial data(Landsat 5 and Landsat 8 satellite image data,POI spatial big data,digital elevation model,etc.),and 12 natural and human factors closely related to urban thermal environment are quickly obtained.The standard deviation ellipse and spatial principal component analysis(PCA)methods are used to analyze the effect of urban human residential thermal environment and its influencing factors.The results showed that the heat island area increased by 547 km~2 and the maximum surface temperature difference reached 10.1℃during the period 2000–2016.The spatial distribution of urban heat island was mainly concentrated in urban built-up areas,such as industrial and commercial agglomerations and densely populated urban centers.The spatial distribution pattern of heat island is gradually decreasing from the urban center to the suburbs.There were multiple high-temperature centers,such as Wuyi square business circle,Xingsha economic and technological development zone in Changsha County,Wangcheng industrial zone,Yuelu industrial agglomeration,and Tianxin industrial zone.From 2000 to 2016,the main axis of spatial development of heat island remained in the northeast-southwest direction.The center of gravity of heat island shifted 2.7 km to the southwest with the deflection angle of 54.9°in 2000–2009.The center of gravity of heat island shifted to the northeast by 4.8 km with the deflection angle of 60.9°in 2009–2016.On the whole,the change of spatial pattern of thermal environment in Changsha was related to the change of urban construction intensity.Through the PCA method,it was concluded that landscape pattern,urban construction intensity and topographic landforms were the main factors affecting the spatial pattern of urban thermal environment of Changsha.The promotion effect of human factors on the formation of heat island effect was obviously greater than that of natural factors.The temperature would rise by 0.293℃under the synthetic effect of human and natural factors.Due to the complexity of factors influencing the urban thermal environment of human settlements,the utilization of multi-source data could help to reveal the spatial pattern and evolution law of urban thermal environment,deepen the understanding of the causes of urban heat island effect,and clarify the correlation between human and natural factors,so as to provide scientific supports for the improvement of the quality of urban human settlements.
基金Foundation of Education Department in Hunan Province, No.05C451
文摘This research systematically analyses land-use map of Changsha city in different periods of time. The spatial form and structural evolution was analysed by studying indices such as city land-use structure proportion, expansion intensity, economic flexibility, population flexibility, changing compactness index and so on. The dynamic mechanism of urban land expansion has been discussed by integrating the regional social economy development situation and many aspects such as the physiographical surrounding, population and economic development, traffic infrastructure, planning and regional development tactic and system innovation. The research indicates that the urban land expansion speed and intensity have steadily increased in Changsha from 1949 to 2004. The expansion form has been from a single external expansion to a combination form of external and internal expansion, from a circular or linear continuous form to a blocky or agglomeration shape. Overall, the urban land expansion of Changsha city is a phasic, diversified and complex process. And no matter what the stage is, it is an organic system containing multiple speed, pattern and shape, which are driven by multiple impetuses. The dominant feature at different stages was highlighted because of the balance and fluctuation between different forces, and the existing urban land border and shape have resulted from the joint efforts of these phasic forces.
基金National Natural Science Foundation of China, No.40771198Hunan Provincial Natural Science Foundation of China, No.08JJ6023
文摘Although traditional urban expansion simulation models can simulate dynamic features, these models fail to address complex changes produced by different agents＇ behaviors. The paper has built up a set of spatial-temporal land resource allocation rules and developed a dynamic urban expansion model based on a multi-agent system, which can simulate the interaction among different agents, such as residents, peasants, and governments. This model is applied to simulate urban expansion process taking Changsha City, in China as a study area. The results show that this model can not only reflect basic characteristics of urban expansion, but also help explain the reasons for urban expansion process and understand the effect of agents＇ behavior on the expansion process, and provide insights into the causing factors behind the expansion. In addition, in contrast to simulation results with land use classification map from remote sensing images, the precision of the simulation reached over 68% with higher precision than cellular automata model according to the cell-by-cell comparison. The results suggest that the model can help to provide land use decision making support to government and urban planners.
文摘The research purpose is to accurately reveal the temporal and spatial law of the urban expansion of Changsha-Zhuzhou-Xiangtan, one of the seven major urban agglomeration areas in China, and provide decision-making basis for the future urban construction land layout and regional development policy-making. Based on the night lighting data (DMSP/OLS), this paper extracts the boundary of the urban construction land of Changsha-Zhuzhou-Xiangtan urban agglomeration from 1993 to 2017, and quantitatively studies the spatial and temporal characteristics of the expansion of the metropolitan area in the past 25 years according to the methods of spatial expansion analysis, center of gravity migration measurement, landscape pattern index, spatial autocorrelation, etc. The results show that: 1) it is scientific and feasible to extract urban agglomeration construction land by the method of auxiliary data comparison for the study of urban expansion;2) the expansion of regional space in Changsha-Zhuzhou-Xiangtan metropolitan area shows a trend of “weakening first and strengthening later”. The construction land keeps increasing, and the expansion form gradually changes from extensive type to intensive type;3) the center of gravity of the metropolitan area fluctuated and repeated in part during the past 25 years, but it was always located in the municipal district of Changsha city. The eastern region, mainly Changsha city, was still the core area of urban agglomeration expansion;4) strengthening the territorial space protection and control of ecological green core in the metropolitan area is a key measure for the high-quality development of urban agglomeration.
文摘By analyzing the status quo of land resources in " green heart" area of Changsha-Zhuzhou-Xiangtan urban agglomeration,and problems existing in land management,this article puts forward some countermeasures and proposals as follows:establish new land management mechanism in " green heart" area;based on land planning," green heart" overall planning and policies and regulations,manage land and promote the protection of urban ecological environment.
文摘[ Objective] The research aimed to study relationship between summer electricity and meteorological factors. [ Method] Electrical load characteristics in Changsha during 2007 -2010 were analyzed. Correlation analysis between electrical load and meteorological factors （daily average temperature, the maximum temperature, the minimum temperature, rainfall, wind, relative humidity and atmospheric pressure） during July - September of 2007 -2010 was conducted. [ Result] Changes of the meteorological factors could directly affect electrical load, and temperature was the first influence factor. Prediction model of summer electrical load in Changsha was established by regression analysis method.[ Conclusion] The research could provide reference basis for prediction of the electrical load in Changsha.
基金Projects(2018YFC1903301,2018YFC1801805)supported by the National Key R&D Program of China
文摘The Changsha-Xiangtan-Zhuzhou City Group is a heavy industrial district and accepted as the serious pollution area in the Xiangjiang River basin.In this study,7 metals(Pb,Hg,Cd,As,Zn,Cu and Se)and the river water quality parameters including pH,dissolved oxygen(DO),Escherichia coli(E.coli),potassium permanganate index(CODMn),dichromate oxidizability(CODCr),five-day biochemical oxygen demand(BOD5),ammonia nitrogen(NH4+-N),total nitrogen(TN),total phosphorus(TP)and fluoride(F)in 18 sampling sites of the Changsha-Xiangtan-Zhuzhou section are monthly monitored in 2016,which is the year to step into the second stage of the“Xiangjiang River Heavy Metal Pollution Control Implementation Plan”.It is found that E.coli,TN and TP are the main pollutants in the Changsha-Zhuzhou-Xiangtan section,and the pollution of heavy metal is not serious but As with potential risk to local people especially children should be concerned.In addition,Xiangtan city is mainly featured with heavy metal pollution,while Zhuzhou and Changsha city are both featured with other pollutants from municipal domestic sewage.
基金supported by the National Nature Science Foundation of China (NSFC4077111 andKZCX2-YW-437)
文摘The aim of the study was to develop an index to assess the environmental risk of P loss potential in vegetable soils with chronic difference of plantation in the suburbs of Changsha, Hunan Province, China. Chemical methodology was used to study soil phosphorus status and the relationships between available P in soil and potential soil leaching P. The results showed that there was a significant linear relationship between Olsen P and CaC12-P or P concentration in soil solution. Olsen P increased sharply when either CaCI2-P or P concentration in soil solution reached a certain level. It was confirmed that 80 mg kg-t of Olsen P was the critical value of soil P leaching in the vegetable soils. P leaching probability over the critical was assessed by GIS and indicator Kriging and four secondary risks of phosphorus leaching loss were defined. In the area with vegetable cropping for over 30 yr （Chenjiadu） and 10-15 planting years （Huangxingzhen）, the indices of phosphorus leaching loss risk were 3 and 2.93, respectively. These two areas belonged to strong secondary of risk of phosphate leaching loss. In the new vegetable planting field less than 2 yr （Ningxiang）, the index was 0.06, which had almost no risk of phosphorus leaching. In vegetable soils in the suburban region of Changsha, the phosphorus leaching peotential is high and the phosphorus leaching loss is related to chronic length of vegetable cropping.
基金National Natural Science Foundation of China,No.42101214Natural Science Foundation of Guangxi Zhuang Autonomous Region,No.2018GXNSFDA281032China Postdoctoral Science Foundation,No.2021M703177。
文摘Using the system dynamics simulation software Vensim PLE, we built a model to simulate the development of resilient human settlement in Changsha. This model includes five subsystems: living, economy, society, ecology and engineering. The model simulates various scenarios, based on different parameter settings to predict the trend of human settlement from 2019–2040 in Changsha. It puts forward four development programs under different simulation scenarios. The results show that the current system of human settling lacks self-regulation and feedback, where simple increases in the economy and urbanization cannot drive the internal system to progress positively. In contrast, the resilient human settlement program is more reasonable and scientific, up to the year 2040, the production, living and ecological environment of residents will be markedly improved in terms of per capita disposable income, per capita floor space and medical insurance coverage;these will increase by 98.9%, 39.7%, and 170.7%, respectively. This system of developing resilient human settlement provides feedback according to the internal relation loops and thus drives itself to adjust and recover, achieving harmonious and sustainable development. In the forthcoming development, we should take the initiative to optimize economic development and upgrade industrial structures, establish emergency plans and response mechanisms to enhance human quality of life.
基金Acknowledgement： The authors appreciate the support of the West Transportation Construction Science and Technology of China （No. 200331879805） and Hunan Provincial Natural Science Foundation of China （No. 07JJ3111）.
文摘The highway construction inevitably may cause certain influence to the cultural heritage and the natural environment along the route, particularly in design stage; if the route selection is unreasonable, it will certainly impact the natural resource seriously along the route. On the contrary, good design can reasonably develop, use, protect and promote the value of cultural heritage and natural environment. Changsha to Jishou （Chang-Ji） freeway is one section of Changsha to Chongqing freeway, which is one of the eight big west channels as planned in China; two cities of Changde and Huaihua and one autonomous region of Xianxi in western Hunan province, along which the cultural heritage and the natural resource are rich, and the natural landscape is exquisite. This paper investigates and analyzes the natural resources along the route of Chang-Ji freeway, puts forward some protection design evaluation indexes for mountain area freeway by the thought of context sensitive design. At last, the paper introduces the effect of applying the indexes to select route of Chang-Ji freeway.
基金supported by grants from the National Key Research and Development Program of China(Grant No.2019YFA0110703)the National Natural Science Foundation of China(Grant No.82272102)the Natural Science Foundation of Hunan Province,China(Grant No.2021JJ31018).
文摘Background:Xenotransplantation is a potential way to reduce the shortage of the needed organ grafts for the end-stage disease.Immune rejection,physiological incompatibility and bio-safety are the most critical issues.Methods:To ensure the safety and efficacy of gene editing,second-and thirdgeneration sequencing technologies have allowed us to obtain a clearer genetic background of donor pigs for xenotransplantation.Based on the Changsha Communiqué,the local DPF-excluded lists and DPF donor facility were established in Changsha,China.A pig-to-human islet clinical trial was conducted and overseen by the respective Chinese governmental agency.Results:The DPF standards for pig husbandry eliminated specific pathogens in donor pigs.We have established a PERV-C free,genetic information clean,DPF donor for xenotransplantation.A clinical trial of ten adult patients(9M:1F)with type 1 diabetes who received DPF porcine islet xenotransplantation via the portal vein were performed.Clinical accepted immunosuppressant drugs and autologous Treg were used for controlling immune rejection.No cross-species infection events occurred in this trial,and importantly,no cross-species transmission of PERV was found.Conclusions:Xenotransplantation is a pioneer study and safety is the most important issue.The fundamental principles for establishing xenotransplantation donor pigs should follow the Changsha Communiqué(2008),the second WHO consultation,and the 2018 Changsha Communiquéwhich would finally help reducing the risks of xenotransplantation.
文摘Using detection data with high space-time resolution from the wind profile radar and millimeter wave cloud radar of Changsha station,and combining observation data of ground automatic station,heavy precipitation process in Changsha area from June 29 to July 1,2017 was analyzed.The results showed that the atmospheric temperature advection was calculated by inversion of wind profile radar data of boundary layer,and it could intuitively analyze changes of atmospheric temperature advection before and after precipitation process.The variation characteristics of intensity,thickness and height of warm and cold advection in the upper and lower levels were highly related to the evolution of the precipitation process.The millimeter wave cloud radar can better reflect the vertical structure and evolution of the cloud over the observatory,and had certain indications for the structure characteristics of cloud before the starting of precipitation.When the strong reflectivity started to approach the ground,it also meant that heavy precipitation began to appear.
基金Supported by Special Project of Research Business Forecast of Hunan Meteoro-logical Bureau(XQKJ21C001).
文摘Using NCEP reanalysis data,high-altitude and ground observation data,numerical model data,satellite and radar data,formation cause and forecast deviation of an extreme rainstorm process in Changsha urban area at night on June 9,2020 were analyzed.The results showed that(1)the extreme rainstorm process developed near the surface convergence line,with strong localization,short duration and large hourly rainfall intensity.(2)Under the high temperature and high humidity environment,the low-level cold advection and the hot low-pressure system interacted,and the potential con-vective unstable energy was released,and a strong convective weather was formed.(3)The convergence of water vapor in the lower layer and the strong upward movement provided sufficient water vapor for the rainstorm.The low-centroid thunderstorm was the main reason for the extreme rainstorm.(4)The forecast deviation of the numerical model to the low-level shear line and the mesoscale convergence line was an important reason for the forecast deviation of the heavy rainfall area.
文摘This paper designed the index system for the evaluation of landscape health influence factors of Yanghu Wetland Park from tourists’ perspective,applied the principal component method to extract 19 indexes of 5 public factors,i.e.policy system,ecological environment,functional management,landscape facility,tourists’ behavior,to analyze the influence factors for the landscape health of national wetland parks.The results showed that tourists’ evaluation varied greatly on the significance of 19 indexes and their satisfaction in the influence factor system of landscape health,then used IPA modified model to classify the factors influencing landscape health of Yanghu Wetland Park into 4 categories,defined the orientation of the 19 indexes in the 4 categories,and proposed the corresponding landscape health optimization strategies based on the analysis results of IPA modified model.
基金Rehabilitation Research Project of Hunan Disabled Persons’Federation(No.2020XK014).
文摘Objective:the positioning of secondary hospitals in the community rehabilitation work system and the status of community medical rehabilitation ser-vices for the disabled in Changsha were clarified through investigation and study of the 2019 income of a second-ary general hospital in Changsha.Suggestions from var-ious parties were integrated to provide feasible ideas for expanding the role of secondary hospitals in community rehabilitation.Methods:the 2019 income of a secondary general hospital in Changsha was statistically analyzed,a community rehabilitation questionnaire was designed,and a field survey was carried out focusing on 19 issues including rehabilitation service items,rehabilitation facil-ities and equipment,and the satisfaction of rehabilitation practitioners.Results:in the total hospitalization expenses of a secondary general hospital in Changsha city in 2019,rehabilitation physiotherapy expenses accounted for 7%,and drug treatment expenses accounted for 25%.In addi-tion,in the survey of community rehabilitation service sat-isfaction for the disabled,the difference between the very dissatisfied and very satisfied groups was statistically sig-nificant(P<0.05).Conclusion:taking a secondary gener-al hospital in Changsha city as an example,the treatment methods in secondary general hospitals are still dominated by traditional drug therapy,and the disabled are not sat-isfied with community rehabilitation services.Therefore,rehabilitation treatment projects to meet the rehabilitation needs of the disabled should be promoted in hospitals.
文摘A statistical analysis on the simultaneous observation data of the temperature inside and outside the themometer shelter in Changsha during summer of 2011 and 2012 was carried out. The results show that the temperature outside the themometer shelter is higher（ lower） than that inside the themometer shelter in the daytime（ nighttime）. However,there exists a similar variation trend for the average temperature and the extremely maximum temperature inside and outside the themometer shelter in summer. The average temperature and the extremely maximum temperature outside the themometer shelter are higher than that inside the themometer shelter. Furthermore,there exists a difference between the temperatures inside and outside the themometer shelter during different weather conditions. The difference of average temperature reaches 1. 2 ℃ in rainy day,2. 8 ℃ in cloudy day and 3. 1 ℃ in sunny day,and the extremely maximum temperature difference reaches 6. 4 ℃. Especially for the days of high temperature ≥35 ℃,there is 61 high temperature days inside the themometer shelter,while there is 125 high temperature days inside the themometer shelter during 2011- 2012. Furthermore,the extremely maximum temperatures inside and outside the themometer shelter are 38. 9 and42. 0 ℃ respectively. Rainfall and showery rain are the most effective ways to relieve the high temperature in summer. Therefore,the difference between the temperatures inside and outside the themometer shelter should be taken into account in the high temperature forecast and public meteorological service.
文摘The balanced development of the elementary education sector has been a long goal pursued by the education departments of various places, and is also an outcome expected by the people. Based on a study of the equilibrium of the spatial distribution of the capacity saturation models of all the primary schools in Changsha’s (China) five core districts, the results show that the overall geographical distribution of the primary schools in Changsha is relatively balanced, based on the natural characteristics of Changsha, such as human geography, and the moderate gradient between the central urban area and the primary schools in the suburbs and outer suburbs. Then the Theil index model was introduced, and the results of the model analysis show that the differences between elementary schools in Changsha urban area are relatively small, and the main differences originate from between districts rather than within districts, and subtle differences among regions mainly reflect in the teacher strength.
