Objective: To study the effects of enteral nutrition intervention on immune nutritional status and radiation damage in patients with esophageal cancer radiotherapy. Methods: Patients with esophageal cancer who underwe...Objective: To study the effects of enteral nutrition intervention on immune nutritional status and radiation damage in patients with esophageal cancer radiotherapy. Methods: Patients with esophageal cancer who underwent radiotherapy in West China Hospital, Sichuan University between January and October 2017 were chosen as the research subjects and divided into the experimental group who received enteral nutrition intervention and the control group who received routine intervention. The contents of nutrition indicators and radiation damage markers in serum as well as the contents of immune cells in peripheral blood were determined before radiotherapy and after radiotherapy ended. Results: Compared with those before radiotherapy, serum ALB, PA, TRF and RBP contents as well as peripheral blood Th cell, NK cell, Breg cell and Treg cell contents of experimental group did not change significantly while serum PDGF-BB, TGF-β1, CTGF, TNF-α and SAA contents were significantly higher after radiotherapy;serum ALB, PA, TRF and RBP contents as well as peripheral blood Th cell and NK cell contents of control group were significantly lower while serum PDGF-BB, TGF-β1, CTGF, TNF-α and SAA contents as well as peripheral blood Breg cell and Treg cell contents were significantly higher after radiotherapy;serum ALB, PA, TRF and RBP contents as well as peripheral blood Th cell and NK cell contents of experimental group after radiotherapy were higher than those of control group while serum PDGF-BB, TGF-β1, CTGF, TNF-α and SAA contents as well as peripheral blood Breg cell and Treg cell contents were lower than those of control group. Conclusion: enteral nutrition intervention can improve immune nutritional status and reduce radiation damage in patients with esophageal cancer radiotherapy.展开更多
目的分析肿瘤患儿父母共享决策的体验,为医护人员制订干预方案提供参考并促进共享决策。方法检索Cochrane Library、CINAHL、PubMed、Embase、Web of Science、PsycINFO、中国生物医学文献数据库、中国知网、万方数据知识服务平台、维...目的分析肿瘤患儿父母共享决策的体验,为医护人员制订干预方案提供参考并促进共享决策。方法检索Cochrane Library、CINAHL、PubMed、Embase、Web of Science、PsycINFO、中国生物医学文献数据库、中国知网、万方数据知识服务平台、维普中文科技期刊数据库中关于肿瘤患儿父母共享决策体验的文献,检索时限为建库至2023年10月25日。为了保证文献的质量,采用澳大利亚JBI循证卫生保健中心的质性研究质量评价标准(2020版)对文献进行评价,运用汇集性整合法整合最终的结果。结果共纳入6篇文献,提取25个主题,分为13个类别并将其分组合并为4个整合结果:共享决策的主要方式、共享决策困扰、共享决策过程中积极寻求帮助、共享决策相关情感体验。结论医护人员应及时关注肿瘤患儿父母的共享决策体验,并给予充分的心理支持,从而帮助父母选择最佳治疗方案,改善患儿的生活质量。展开更多
目的探讨食管胃结合部腺癌(adenocarcinoma of esophagogastric junction,AEG)的No.4d、5、6、12组淋巴结转移的规律和相关因素。方法回顾2015年6月至2018年5月北京大学肿瘤医院胃肠肿瘤中心一病区行全胃切除的AEG病人的临床及病理资料...目的探讨食管胃结合部腺癌(adenocarcinoma of esophagogastric junction,AEG)的No.4d、5、6、12组淋巴结转移的规律和相关因素。方法回顾2015年6月至2018年5月北京大学肿瘤医院胃肠肿瘤中心一病区行全胃切除的AEG病人的临床及病理资料,分析胃下部淋巴引流区域淋巴结即No.4d、5、6、12组淋巴结的转移率,并分析各临床病理因素与其相关性,计数资料的组间比较采用χ^2检验,计量资料的组间比较采用两独立样本t检验。结果该研究共纳入77例病人,其中48例(62.33%)合并淋巴结转移,转移率较高的为No.3、1、7组淋巴结,分别为43.42%、22.08%、22.08%。No.4d、5、6、12组的淋巴结转移率分别为5.26%、3.90%、1.30%、1.37%,胃下部淋巴引流区域淋巴结整体的转移率为9.09%。对各临床病理因素的分析结果显示,仅病理T分期与胃下部淋巴引流区域淋巴结转移相关。结论单中心回顾性数据显示,AEG病人胃下部淋巴引流区域淋巴结整体转移率为9.09%,pT 4期为胃下部淋巴引流区域淋巴结转移的高危因素。展开更多
文摘Objective: To study the effects of enteral nutrition intervention on immune nutritional status and radiation damage in patients with esophageal cancer radiotherapy. Methods: Patients with esophageal cancer who underwent radiotherapy in West China Hospital, Sichuan University between January and October 2017 were chosen as the research subjects and divided into the experimental group who received enteral nutrition intervention and the control group who received routine intervention. The contents of nutrition indicators and radiation damage markers in serum as well as the contents of immune cells in peripheral blood were determined before radiotherapy and after radiotherapy ended. Results: Compared with those before radiotherapy, serum ALB, PA, TRF and RBP contents as well as peripheral blood Th cell, NK cell, Breg cell and Treg cell contents of experimental group did not change significantly while serum PDGF-BB, TGF-β1, CTGF, TNF-α and SAA contents were significantly higher after radiotherapy;serum ALB, PA, TRF and RBP contents as well as peripheral blood Th cell and NK cell contents of control group were significantly lower while serum PDGF-BB, TGF-β1, CTGF, TNF-α and SAA contents as well as peripheral blood Breg cell and Treg cell contents were significantly higher after radiotherapy;serum ALB, PA, TRF and RBP contents as well as peripheral blood Th cell and NK cell contents of experimental group after radiotherapy were higher than those of control group while serum PDGF-BB, TGF-β1, CTGF, TNF-α and SAA contents as well as peripheral blood Breg cell and Treg cell contents were lower than those of control group. Conclusion: enteral nutrition intervention can improve immune nutritional status and reduce radiation damage in patients with esophageal cancer radiotherapy.
文摘目的分析肿瘤患儿父母共享决策的体验,为医护人员制订干预方案提供参考并促进共享决策。方法检索Cochrane Library、CINAHL、PubMed、Embase、Web of Science、PsycINFO、中国生物医学文献数据库、中国知网、万方数据知识服务平台、维普中文科技期刊数据库中关于肿瘤患儿父母共享决策体验的文献,检索时限为建库至2023年10月25日。为了保证文献的质量,采用澳大利亚JBI循证卫生保健中心的质性研究质量评价标准(2020版)对文献进行评价,运用汇集性整合法整合最终的结果。结果共纳入6篇文献,提取25个主题,分为13个类别并将其分组合并为4个整合结果:共享决策的主要方式、共享决策困扰、共享决策过程中积极寻求帮助、共享决策相关情感体验。结论医护人员应及时关注肿瘤患儿父母的共享决策体验,并给予充分的心理支持,从而帮助父母选择最佳治疗方案,改善患儿的生活质量。
文摘目的探讨食管胃结合部腺癌(adenocarcinoma of esophagogastric junction,AEG)的No.4d、5、6、12组淋巴结转移的规律和相关因素。方法回顾2015年6月至2018年5月北京大学肿瘤医院胃肠肿瘤中心一病区行全胃切除的AEG病人的临床及病理资料,分析胃下部淋巴引流区域淋巴结即No.4d、5、6、12组淋巴结的转移率,并分析各临床病理因素与其相关性,计数资料的组间比较采用χ^2检验,计量资料的组间比较采用两独立样本t检验。结果该研究共纳入77例病人,其中48例(62.33%)合并淋巴结转移,转移率较高的为No.3、1、7组淋巴结,分别为43.42%、22.08%、22.08%。No.4d、5、6、12组的淋巴结转移率分别为5.26%、3.90%、1.30%、1.37%,胃下部淋巴引流区域淋巴结整体的转移率为9.09%。对各临床病理因素的分析结果显示,仅病理T分期与胃下部淋巴引流区域淋巴结转移相关。结论单中心回顾性数据显示,AEG病人胃下部淋巴引流区域淋巴结整体转移率为9.09%,pT 4期为胃下部淋巴引流区域淋巴结转移的高危因素。
