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STUDY ON ENHANCEMENT OF TUMOR-KILLING EFFECT AND FORMATION OF NEW FLUOROPHORE IN TUMOR CELLS
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作者 范贤俊 曹恩华 +1 位作者 池顺姬 王玉霞 《Chinese Medical Sciences Journal》 CAS CSCD 1990年第2期107-111,共5页
Hyperthermia (42-44℃) and photosensitizing therapy can destroy S180 tumor cells,reducemalignant ascites and prolong the survival times of mice with carcinomas.The highestcurative effect was observed when using a comb... Hyperthermia (42-44℃) and photosensitizing therapy can destroy S180 tumor cells,reducemalignant ascites and prolong the survival times of mice with carcinomas.The highestcurative effect was observed when using a combination of the two treatments.Heating to44℃ has a greater destructive effect on tumor cells than has heating to 42℃.The resultsshow that this is due to a synergistic interaction between these two treatments.The fluores-cence spectrum of S180 cells was determined before and alter treatment,and the indicationwas that the synergistic effect is probably related to a new fluorescence product;the greaterthe intensity of the new fluorescence、the more marked the synergy of hyperthermia andphotosensitizing therapy.The maximum emission wavelength was 460nm (excitation wave-length 370nm). 展开更多
关键词 HYPERTHERMIA HPD FLUOROPHORE SYNERGISTIC interaction
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