Numerous hypotheses predict associations between phenotype-associated breeder traits and reproductive success.In secondary cavity-nesting passerine birds,which have been investigated most,up to more than 90parental ch...Numerous hypotheses predict associations between phenotype-associated breeder traits and reproductive success.In secondary cavity-nesting passerine birds,which have been investigated most,up to more than 90parental characteristics have been linked to at least one field measure of breeding performance.However,within study populations,different parental traits,such as clutch size,first-egg date,egg size,nest architecture,plumage colour,adult morphometry,or song performance,are often weakly correlated across female and/or male breeders.Furthermore,many of these studies have been conducted outside the theoretical framework of the'Individual Optimisation Hypothesis' of clutch size(IOH).IOH predicts that:(i) females with larger clutches will have larger broods at hatching and fledging compared to those with smaller clutches;and(ii) clutch size,which is adaptively adjusted to the parents' ability to rear nestlings,should always maximize the percentage of eggs producing fledglings so that variation in clutch size becomes disconnected from variation in breeding success.In this paper,we present the first detailed review of implications of IOH for parental characters other than clutch size.Our review covered 188 non-experimental studies and 1074 statistical results that examined how parental traits influence breeding success in Western Palearctic Great Tits(Parus major),Blue Tits(Cyanistes spp.),and flycatchers(Ficedula spp.).Clutch size explained one third of the variation in brood size at hatching and fledging within study populations.However,most parental characteristics associated weakly with the number of hatchlings or fledglings,likely because they did not correlate with clutch size.Overall,parental traits were poorly correlated with the proportion of hatchlings and fledglings per egg.We discuss why intraspecific variation in phenotype-associated breeder traits is often disconnected from interindividual differences in breeding success,and highlight the importance of underexplored research problems in avian breeding biology.展开更多
When incompletely isolated taxa coexist in a patchy environment （e.g. mosaic hybrid zones, host-race complexes）, patterns of variation may differ between selected traits/genes and neutral markers. While the genetic ...When incompletely isolated taxa coexist in a patchy environment （e.g. mosaic hybrid zones, host-race complexes）, patterns of variation may differ between selected traits/genes and neutral markers. While the genetic structure of selected traits/loci tends to coincide with habitat variables （producing Genetic-Environment Association or GEA）, genetic differentiation at neutral loci unlinked to any selected locus rather depends on geographic connectivity at a large scale （e.g. Isolation- By-Distance or IBD）, although these loci often display GEA at a small scale. This discrepancy has been repeatedly taken as evi- dence for parallel primary divergence driven by local adaptation. We argue that this interpretation needs to be addressed more thoroughly by considering the alternative hypothesis that speciation was initiated in allopatry and secondary introgression has subsequently erased the signal of past differentiation at neutral loci. We present a model of neutral introgression after secondary contact in a mosaic hybrid zone, which describes how GEAs dissipate with time and how neutral variation self-organizes accord- ing to the environmental and geographic structures. We show that although neutral loci can be affected by environmental selection they are often more affected by history and connectivity： the neutral structure retains the initial geographic separation more than it correlates with the environment during the colonization and introgression phases, and then converges to a migration-drift balance, the most frequent outcome of which is GEA at a local scale but IBD at a large scale. This is the exact pattern usually attributed to parallel ecological speciation. Introgression is heterogeneous in space and depends on the landscape structure （e.g. it is faster in small patches, which are more impacted by immigration）. Furthermore, there is no directionality in the association and it is possi- ble to observe reversed GEAs between distant regions. We argue that the history of differentiation should ideally be reconstructed with selected loci or neutral loci linked to them, not neutral ones, and review some case studies for which the hypothesis of a long co-existence of co-adapted genetic backgrounds might have been refuted too hastily [Current Zoology 59 （1）： 72-86, 2013].展开更多
The expanding scale and increasing rate of marine biological invasions have been documented since the early 20th century. Besides their global ecological and economic impacts, non-indigenous species （NIS） also have ...The expanding scale and increasing rate of marine biological invasions have been documented since the early 20th century. Besides their global ecological and economic impacts, non-indigenous species （NIS） also have attracted much attention as opportunities to explore important eco-evolutionary processes such as rapid adaptation, long-distance dispersal and range expansion, and secondary contacts between divergent evolutionary lineages. In this context, genetic tools have been extensively used in the past 20 years. Three important issues appear to have emerged from such studies. First, the study of NIS has revealed unexpected cryptic diversity in what had previously been assumed homogeneous entities. Second, there has been surprisingly little evidence of strong founder events accompanying marine introductions, a pattern possibly driven by large propagule loads. Third, the evolutionary processes leading to successful invasion have been difficult to ascertain due to faint genetic signals. Here we explore the potential of novel tools associated with high-throughput sequencing （HTS） to address these still pressing issues. Dramatic increase in the number of loci accessible via HTS has the potential to radically increase the power of analyses aimed at species delineation, exploring the population genomic consequences of range expansions, and examining evolutionary processes such as admixture, introgression, and adaptation. Nevertheless, the value of this new wealth of genomic data will ultimately depend on the ability to couple it with expanded ＂traditional＂ efforts, including exhaustive sampling of marine populations over large geographic scales, integrated taxonomic analyses, and population level exploration of quantitative trait differentiation through common-garden and other laboratory experiments.展开更多
Evaluating the fitness of hybrids can provide important insights into genetic differences between species or diverging populations.We focused on surface-and cave-ecotypes of the widespread Atlantic molly Poecilia mexi...Evaluating the fitness of hybrids can provide important insights into genetic differences between species or diverging populations.We focused on surface-and cave-ecotypes of the widespread Atlantic molly Poecilia mexicana and raised F1 hybrids of reciprocal crosses to sexual maturity in a common-garden experiment.Hybrids were reared in a fully factorial 2 x 2 design consisting of lighting(light vs.darkness)and resource availability(high vs.low food).We quantified survival,ability to realize their full reproductive potential(i.e.,completed maturation for males and 3 consecutive births for females)and essential life-history traits.Compared to the performance of pure cave and surface fish from a previous experiment,F1s had the highest death rate and the lowest proportion of fish that reached their full reproductive potential.We also uncovered an intriguing pattern of sex-specific phenotype expression,because male hybrids expressed cave molly life histories,while female hybrids expressed surface molly life histories.Our results provide evidence for strong selection against hybrids in the cave molly system,but also sug-gest a complex pattern of sex-specific(opposing)dominance,with certain surface molly genes being dominant in female hybrids and certain cavemollygenes beingdominant in malehybrids.展开更多
Reproductive traits are central to organismal fitness,and so the factors influencing patterns of reproduction and offspring survival are at the heart of biology.Making use of breeding data collected over 16 years at t...Reproductive traits are central to organismal fitness,and so the factors influencing patterns of reproduction and offspring survival are at the heart of biology.Making use of breeding data collected over 16 years at the King Khalid Wildlife Research Centre in Saudi Arabia,we investigated the reproductive biology of Arabian gazelles Gazella arabica.Offspring survival was mainly a function of birth weight,with heavier offspring having higher survival rates than lighter offspring.However,while sons were heavier than daughters,daughters had higher survival rates.We could not find evidence that giving birth to sons negatively impacts offspring weight in the following year.We uncovered large narrow-sense heritability(h2)in offspring weight at birth,while maternal effects(m2)on birth weight were of lesser importance.However,maternal effects on offspring survival were strong until weaning age,while paternal effects dominated survival to sexual maturity and first reproduction.We propose that variation in maternal postnatal care might overshadow the effects of maternal inheritance of birth weights,while the overall strong heritability of weight at birth and the paternal effects on survival llustrates strong variance in sire fitness based on genetic quality,suggesting a role for sexual selectionbyfemalemate choiceinwildpopulations.展开更多
This study endeavour assesses agromorphological likeness between initial introductions and regenerated accessions at the International Coconut Genebank for Africa and the Indian Ocean (ICG-AIO) based in C?te d’Ivoire...This study endeavour assesses agromorphological likeness between initial introductions and regenerated accessions at the International Coconut Genebank for Africa and the Indian Ocean (ICG-AIO) based in C?te d’Ivoire. Ten couples of parental (G0) and regenerated (G1) accessions of Tall coconut palms were analyzed using Principal Component Analysis (PCA) and Multiple Analysis of Variance (MANOVA) from 26 agromorphological characters. The main results showed a relative decrease in the expression of the phenotypical traits concerning the component of the fruit, height and vigor of the stem and yield of bunches and fruits after one regeneration cycle. But, a high proportion (69%) of studied characters from leaf, inflorescence and nut components showed likeness between G0 and G1 accessions. After one regeneration cycle, the controlled pollination method guarantees significant conservation of the expression of the majority of agromorphological traits. Consequently, regenerated accessions of Tall coconut palms can be used to pursue research and development programs in C?te d’Ivoire.展开更多
Soil organic matter (SOM) is a complex heterogeneous mixture formed through decomposition and organo-mineral interactions, and characterization of its composition and biogeochemical stability is challenging. From this...Soil organic matter (SOM) is a complex heterogeneous mixture formed through decomposition and organo-mineral interactions, and characterization of its composition and biogeochemical stability is challenging. From this perspective, Rock-Eval® is a rapid and efficient thermal analytical method that combines the quantitative and qualitative information of SOM, including several parameters related to thermal stability. This approach has already been used to monitor changes in organic matter (OM) properties at the landscape, cropland, and soil profile scales. This study was aimed to assess the stability of SOM pools by characterizing the grain size fractions from forest litters and topsoils using Rock-Eval® thermal analysis. Litter (organic) and topsoil samples were collected from a beech forest in Normandy (France), whose management in the last 200 years has been documented. Fractionation by wet sieving was used to separate large debris (> 2 000 μm) and coarse (200–2 000 μm) and fine particulate OM (POM) (50–200 μm) in the organic samples as well as coarse (200–2 000 μm), medium (50–200 μm), and fine (< 50 μm) fractions of the topsoil samples. Rock-Eval® was able to provide thermal parameters sensitive enough to study fine-scale soil processes. In the organic layers, quantitative and qualitative changes were explained by the progressive decomposition of labile organic compounds from plant debris to the finest organic particles. Meanwhile, the grain size fractions of topsoils presented different characteristics. The coarse organo-mineral fractions showed higher C contents, albeit with a different composition, higher thermal stability, and greater decomposition degree than the plant debris forming the organic layer. These results are consistent with those of previous studies that microbial activity is more effective in this fraction. The finest fractions of topsoils showed low C contents, the highest thermal stability, and low decomposition degree, which can be explained by the stronger interactions with the mineral matrix. Therefore, it is suggested that the dynamics of OM in the different size fractions be interpreted in the light of a plant-microbe-soil continuum. Finally, three distinct thermostable C pools were highlighted through the grain size heterogeneity of SOM: free coarse OM (large debris and coarse and fine particles), weakly protected OM in (bio)aggregates (coarse fraction of topsoil), and stabilized OM in the fine fractions of topsoil, which resulted from the interactions within organo-mineral complexes. Therefore, Rock-Eval® thermal parameters can be used to empirically illustrate the conceptual models emphasizing the roles of drivers played by the gradual decomposition and protection of the most thermally labile organic constituents.展开更多
Geogenic lead (Pb) is considered to be less bioavailable than anthropogenic Pb and exerts less effect on the soil fauna. However,Pb contamination in vegetables has been reported in the case of geogenic anomalies, even...Geogenic lead (Pb) is considered to be less bioavailable than anthropogenic Pb and exerts less effect on the soil fauna. However,Pb contamination in vegetables has been reported in the case of geogenic anomalies, even at moderate concentrations (around 170 mgkg^(-1)). In this study, we investigated collembolan communities using both taxonomic- and trait-based approaches and observed fungal communities to assess the effects of a moderate geogenic Pb anomaly on collembolans and fungi in an urban vegetable garden soil.Results indicated that geogenic Pb indeed modified fungi communities and altered the functional structure of collembolan communities in garden soils. Although geogenic Pb presented low bioavailability, it affected soil fauna and vegetables similar to anthropogenic Pb.展开更多
The family Alaudidae,larks,comprises 93-100 species(depending on taxonomy)that are widely distributed across Africa and Eurasia,with single species extending their ranges to North and northernmost South America and Au...The family Alaudidae,larks,comprises 93-100 species(depending on taxonomy)that are widely distributed across Africa and Eurasia,with single species extending their ranges to North and northernmost South America and Australia.A decade-old molecular phylogeny,comprising~80%of the species,revealed multiple cases of parallel evolution and large variation in rates of morphological evolution,which had misled taxonomists into creating many non-monophyletic genera.Here,we reconstruct the phylogeny of the larks,using a dataset covering one mitochondrial and 16 nuclear loci and comprising all except one of the currently recognised species as well as several recently proposed new species(in total 133 taxa;not all loci available for all species).We provide additional support using genome-wide markers to infer a genus-level phylogeny based on near-complete generic sampling(in total 51 samples of 44 taxa across 40 species).Our results confirm the previous findings of rampant morphological convergence and divergence,and reveal new cases of paraphyletic genera.We propose a new subfamily classification,and also that the genus Mirafra is divided into four genera to produce a more balanced generic classification of the Alaudidae.Our study supports recently proposed species splits as well as some recent lumps,while also questioning some of the latter.This comprehensive phylogeny will form an important basis for future studies,such as comparative studies of lark natural history,ecology,evolution and conservation.展开更多
Closely related and co-distributed species usually share a common phylogeographic history,but it remains unclear whether ecologically interacting species can respond synchronously to historical climate changes.Here,we...Closely related and co-distributed species usually share a common phylogeographic history,but it remains unclear whether ecologically interacting species can respond synchronously to historical climate changes.Here,we focused on a fig-pollinator mutualism comprising Ficus pumila var.pumila and its obligate pollinators(morphospecies Wiebesia pumilae),and collected samples across most of their distribution ranges.We employed cytoplasmic DNA sequences and nuclear microsatellite loci to reveal the species composition within the pollinators and to test whether the two mutualists exhibited similar postglacial phylogeographic patterns.We identified three cryptic pollinator species,with two dominant cryptic species exhibiting parapatric distributions in the northern and southern parts of the plant's range,respectively.Similar current spatial genetic structures were detected in the two dominant cryptic pollinator species and the host plant,with both showing eastern and western genetic clusters.Moreover,evidence for postglacial expansion was found for all three species,and their potential refugia during the Last Glacial Maximum were located in the eastern and western parts of their distribution ranges.These results suggest synchronous responses to historical climate changes.Our study demonstrates congruent phylogeographic patterns between obligate mutualists and highlights the role of biogeographic factors in shaping the current biodiversity across trophic levels.展开更多
Diabetes mellitus is a life-threatening chronic metabolic disease caused by lack of insulin and/or insulin dysfunction,characterized by high levels of glucose in the blood(hyperglycemia).Millions worldwide suffer from...Diabetes mellitus is a life-threatening chronic metabolic disease caused by lack of insulin and/or insulin dysfunction,characterized by high levels of glucose in the blood(hyperglycemia).Millions worldwide suffer from diabetes and its complications.Significantly,it has been recognized that type 2 diabetes is an important preventable disease and can be avoided or delayed by lifestyle intervention.Presently,there are many chemical and biochemical hypoglycemic agents(synthetic drugs),that are used in treating diabetes and are effective in controlling hyperglycemia.However,as they may have harmful side-effects and fail to significantly alter the course of diabetic complications,natural anti-diabetic drugs from medicinal plants have attracted a great deal of attention.Medicinal mushrooms have been valued as a traditional source of natural bioactive compounds over many centuries and have been targeted as potential hypoglycemic and anti-diabetic agents.Bioactive metabolites including polysaccharides,proteins,dietary fibres,and many other biomolecules isolated from medicinal mushrooms and their cultured mycelia have been shown to be successful in diabetes treatment as biological antihyperglycemic agents.In this review we discuss the biological nature of diabetes and,in particular,explore some promising mushrooms that have experimental anti-diabetic properties,preventing or reducing the development of diabetes mellitus.The importance of medicinal mushrooms as agents of medical nutrition therapy and how their metabolites can be used as supportive candidates for prevention and control of diabetes is explored.Future prospects for this field of study and the difficulties and constraints that might affect the development of rational drug products from medicinal mushrooms are discussed.展开更多
Aims Dispersal through space or time via dormancy is one of the primary processes whereby organisms can influence the environment they experience.In plants,strong evolutionary correlations are expected between the two...Aims Dispersal through space or time via dormancy is one of the primary processes whereby organisms can influence the environment they experience.In plants,strong evolutionary correlations are expected between the two kinds of dispersal because both are performed by the seeds and play comparable adaptive roles.In this paper,we investigated these evolutionary correlations using amphicarpic plants,which simultaneously produce aerial seeds with high spatial dispersal propensity and subterranean seeds that do not disperse.Methods We investigated the variation in dormancy and germination in aerial and subterranean seeds of two amphicarpic legumes(Vicia amphicarpa L.and Lathyrus amphicarpos L.)and two closely related homocarpic taxa(Vicia sativa L.and Lathyrus cicera L.)by estimating germination percentages following different combinations of dormancy breaking treatments(i.e.dry after-ripening,cold stratification and physical scarification).Important Findings Our results showed complex interactions between spatial and temporal dispersal.Right after dispersal,aerial seeds were more dormant than their subterranean counterparts,but this trend reversed with after-ripening,as seeds developed physical dormancy.Seeds of homocarpic plants germinated at higher percentages than those of their amphicarpic congeners and lost dormancy homogeneously with after-ripening.Conversely,amphicarpic seeds exhibited varied dormancy strategies modulated by both physiological and physical dormancy.These are expected to increase variation in emergence timing,providing multiple levels of diversifying bet-hedging.This strategy might be adaptive under highly unpredictable conditions by enabling plants to rely on historically favorable sites in good seasons without preventing spatial and temporal migration.展开更多
Medicinal mushrooms have been valued as natural sources of bioactive compounds since times immemorial and have been recognized as potential immunomodulating and anti-cancer agents.Their consumption has consistently be...Medicinal mushrooms have been valued as natural sources of bioactive compounds since times immemorial and have been recognized as potential immunomodulating and anti-cancer agents.Their consumption has consistently been shown to have beneficial effects on human health.Cancer is a generic term for several types of diseases that can be chronic and are responsible for a large number of deaths worldwide.Although there has been considerable progress in modern cancer therapy research,difficulties in understanding the molecular behavior of various types of cancers and the numerous side effects experienced by patients from treatments means that this whole subject area is still problematic.Thus,biological immunotherapy using natural bioactive compounds as supportive treatments in conventional cancer therapies has become in vogue.Bioactive metabolites isolated from medicinal mushrooms have shown potential successes in cancer treatment as biological immunotherapeutic agents that stimulate the immune system against cancer cells.They also act as an effective source of anti-cancer agents,capable of interfering with cellular signal transduction pathways linked to cancer development and progression.In this review we compile available data on the characteristics of medicinal mushrooms that appear to be particularly effective as biological immunotherapeutic agents.Major consideration is given to biological constituents and the putative mechanisms of action by which bioactive compounds act on the human body.Consideration is also given to the benefits that have been claimed for the use of mushrooms in treating cancer and the future prospects of using medicinal mushrooms as potent supportive candidate bioagents for treatment of cancers is discussed.展开更多
Aims For temperate regions such as Northern Europe,predicted climate change patterns include an increase in winter precipitation causing increased risk of flooding,whereas periods of droughts will become more frequent...Aims For temperate regions such as Northern Europe,predicted climate change patterns include an increase in winter precipitation causing increased risk of flooding,whereas periods of droughts will become more frequent in summer.The aim of this study is to explore vari-ations in plant functional trait distributions along a hydrological gradient spanning from recurrent drought events to recurrent flood-ing-mimicking future precipitation patterns.Methods The experiment was conducted in a controlled grassland experi-ment over a period of 3 years.A novel and more extreme hydro-logical regime was achieved by manipulating the flow of a nearby stream thereby creating a continuous hydrological gradient from flooding during winter to drought during summer.Plant commu-nity responses were recorded along this hydrological gradient.Community-weighted trait distribution changes along the gradient were described using null models.Six functional traits were con-sidered:seed mass,leaf dry matter content(LDMC),leaf area,leaf thickness,specific leaf area(SLA)and height.Important findings Over time,responses in plant functional traits changed at the community level.Over the study period consistent changes occurred in the mean trait value of several traits.Communities in relatively dry plots became dominated by species with water-conserving life strategies,represented by high seed mass and thick leaves.In contrast,disturbance-resistant species(high leaf dry matter content)became dominant in flooded plots,indicating that persistence to flooding was the most important factor control-ling the functional structure in those communities.Furthermore,a high abundance of small-seeded species in flooded plots likely indicates higher frequency of species with higher dispersal ability through hydrochory.In conclusion,plant traits are useful for predicting responses to climate change,but abrupt and extreme climate event may cause unexpected responses because they have no analog to previously more stable conditions.We suggest that traits related to dispersal and resistance to disturbance are useful in describing responses to flooding and that these traits should be included in future inves-tigations of plant community responses to extreme hydrological events.展开更多
Exploration of natural sources for novel bioactive compounds has been an emerging field of medicine over the past decades,providing drugs or lead compounds of considerable therapeutic potential.This research has provi...Exploration of natural sources for novel bioactive compounds has been an emerging field of medicine over the past decades,providing drugs or lead compounds of considerable therapeutic potential.This research has provided exciting evidence on the isolation of microbe-derived metabolites having prospective biological activities.Mushrooms have been valued as traditional sources of natural bioactive compounds for many centuries and have been targeted as promising therapeutic agents.Many novel biologically active compounds have been reported as a result of research on medicinal mushrooms.In this review,we compile the information on bioactive structure-elucidated metabolites from macrofungi discovered over the last decade and highlight their unique chemical diversity and potential benefits to novel drug discovery.The main emphasis is on their anti-Alzheimer,antidiabetic,anti-malarial,anti-microbial,anti-oxidant,antitumor,anti-viral and hypocholesterolemic activities which are important medicinal targets in terms of drug discovery today.Moreover,the reader’s attention is brought to focus on mushroom products and food supplements available in the market with claimed biological activities and potential human health benefits.展开更多
Fungi provide ecological and environmental services to humans, as well as health and nutritional benefits, and are vital to numerousindustries. Fermented food and beverage products from fungi are circulating in the ma...Fungi provide ecological and environmental services to humans, as well as health and nutritional benefits, and are vital to numerousindustries. Fermented food and beverage products from fungi are circulating in the market, generating billions of USD.However, the highest potential monetary value of fungi is their role in blue carbon trading because of their ability to sequesterlarge amounts of carbon in the soil. There are no conclusive estimates available on the global monetary value of fungi, primarilybecause there are limited data for extrapolation. This study outlines the contribution of fungi to the global economy and providesa first attempt at quantifying the global monetary value of fungi. Our estimate of USD 54.57 trillion provides a starting point thatcan be analysed and improved, highlighting the significance of fungi and providing an appreciation of their value. This paperidentifies the different economically valuable products and services provided by fungi. By giving a monetary value to all importantfungal products, services, and industrial applications underscores their significance in biodiversity and conservation. Furthermore,if the value of fungi is well established, they will be considered in future policies for effective ecosystem management.展开更多
Fungi are an understudied,biotechnologically valuable group of organisms.Due to the immense range of habitats that fungi inhabit,and the consequent need to compete against a diverse array of other fungi,bacteria,and a...Fungi are an understudied,biotechnologically valuable group of organisms.Due to the immense range of habitats that fungi inhabit,and the consequent need to compete against a diverse array of other fungi,bacteria,and animals,fungi have developed numerous survival mechanisms.The unique attributes of fungi thus herald great promise for their application in biotechnology and industry.Moreover,fungi can be grown with relative ease,making production at scale viable.The search for fungal biodiversity,and the construction of a living fungi collection,both have incredible economic potential in locating organisms with novel industrial uses that will lead to novel products.This manuscript reviews fifty ways in which fungi can potentially be utilized as biotechnology.We provide notes and examples for each potential exploitation and give examples from our own work and the work of other notable researchers.We also provide a flow chart that can be used to convince funding bodies of the importance of fungi for biotechnological research and as potential products.Fungi have provided the world with penicillin,lovastatin,and other globally significant medicines,and they remain an untapped resource with enormous industrial potential.展开更多
This article is the 14th in the Fungal Diversity Notes series,wherein we report 98 taxa distributed in two phyla,seven classes,26 orders and 50 families which are described and illustrated.Taxa in this study were coll...This article is the 14th in the Fungal Diversity Notes series,wherein we report 98 taxa distributed in two phyla,seven classes,26 orders and 50 families which are described and illustrated.Taxa in this study were collected from Australia,Brazil,Burkina Faso,Chile,China,Cyprus,Egypt,France,French Guiana,India,Indonesia,Italy,Laos,Mexico,Russia,Sri Lanka,Thailand,and Vietnam.There are 59 new taxa,39 new hosts and new geographical distributions with one new combination.The 59 new species comprise Angustimassarina kunmingense,Asterina lopi,Asterina brigadeirensis,Bartalinia bidenticola,Bartalinia caryotae,Buellia pruinocalcarea,Coltricia insularis,Colletotrichum fexuosum,Colletotrichum thasutense,Coniochaeta caraganae,Coniothyrium yuccicola,Dematipyriforma aquatic,Dematipyriforma globispora,Dematipyriforma nilotica,Distoseptispora bambusicola,Fulvifomes jawadhuvensis,Fulvifomes malaiyanurensis,Fulvifomes thiruvannamalaiensis,Fusarium purpurea,Gerronema atrovirens,Gerronema favum,Gerronema keralense,Gerronema kuruvense,Grammothele taiwanensis,Hongkongmyces changchunensis,Hypoxylon inaequale,Kirschsteiniothelia acutisporum,Kirschsteiniothelia crustaceum,Kirschsteiniothelia extensum,Kirschsteiniothelia septemseptatum,Kirschsteiniothelia spatiosum,Lecanora immersocalcarea,Lepiota subthailandica,Lindgomyces guizhouensis,Marthe asmius pallidoaurantiacus,Marasmius tangerinus,Neovaginatispora mangiferae,Pararamichloridium aquisubtropicum,Pestalotiopsis piraubensis,Phacidium chinaum,Phaeoisaria goiasensis,Phaeoseptum thailandicum,Pleurothecium aquisubtropicum,Pseudocercospora vernoniae,Pyrenophora verruculosa,Rhachomyces cruralis,Rhachomyces hyperommae,Rhachomyces magrinii,Rhachomyces platyprosophi,Rhizomarasmius cunninghamietorum,Skeletocutis cangshanensis,Skeletocutis subchrysella,Sporisorium anadelphiae-leptocomae,Tetraploa dashaoensis,Tomentella exiguelata,Tomentella fuscoaraneosa,Tricholomopsis lechatii,Vaginatispora favispora and Wetmoreana blastidiocalcarea.The new combination is Torula sundara.The 39 new records on hosts and geographical distribution comprise Apiospora guiyangensis,Aplosporella artocarpi,Ascochyta medicaginicola,Astrocystis bambusicola,Athelia rolfsii,Bambusicola bambusae,Bipolaris luttrellii,Botryosphaeria dothidea,Chlorophyllum squamulosum,Colletotrichum aeschynomenes,Colletotrichum pandanicola,Coprinopsis cinerea,Corylicola italica,Curvularia alcornii,Curvularia senegalensis,Diaporthe foeniculina,Diaporthe longicolla,Diaporthe phaseolorum,Diatrypella quercina,Fusarium brachygibbosum,Helicoma aquaticum,Lepiota metulispora,Lepiota pongduadensis,Lepiota subvenenata,Melanconiella meridionalis,Monotosporella erecta,Nodulosphaeria digitalis,Palmiascoma gregariascomum,Periconia byssoides,Periconia cortaderiae,Pleopunctum ellipsoideum,Psilocybe keralensis,Scedosporium apiospermum,Scedosporium dehoogii,Scedosporium marina,Spegazzinia deightonii,Torula fci,Wiesneriomyces laurinus and Xylaria venosula.All these taxa are supported by morphological and multigene phylogenetic analyses.This article allows the researchers to publish fungal collections which areimportant for future studies.An updated,accurate and timely report of fungus-host and fungus-geography is important.We also provide an updated list of fungal taxa published in the previous fungal diversity notes.In this list,erroneous taxa and synonyms are marked and corrected accordingly.展开更多
文摘Numerous hypotheses predict associations between phenotype-associated breeder traits and reproductive success.In secondary cavity-nesting passerine birds,which have been investigated most,up to more than 90parental characteristics have been linked to at least one field measure of breeding performance.However,within study populations,different parental traits,such as clutch size,first-egg date,egg size,nest architecture,plumage colour,adult morphometry,or song performance,are often weakly correlated across female and/or male breeders.Furthermore,many of these studies have been conducted outside the theoretical framework of the'Individual Optimisation Hypothesis' of clutch size(IOH).IOH predicts that:(i) females with larger clutches will have larger broods at hatching and fledging compared to those with smaller clutches;and(ii) clutch size,which is adaptively adjusted to the parents' ability to rear nestlings,should always maximize the percentage of eggs producing fledglings so that variation in clutch size becomes disconnected from variation in breeding success.In this paper,we present the first detailed review of implications of IOH for parental characters other than clutch size.Our review covered 188 non-experimental studies and 1074 statistical results that examined how parental traits influence breeding success in Western Palearctic Great Tits(Parus major),Blue Tits(Cyanistes spp.),and flycatchers(Ficedula spp.).Clutch size explained one third of the variation in brood size at hatching and fledging within study populations.However,most parental characteristics associated weakly with the number of hatchlings or fledglings,likely because they did not correlate with clutch size.Overall,parental traits were poorly correlated with the proportion of hatchlings and fledglings per egg.We discuss why intraspecific variation in phenotype-associated breeder traits is often disconnected from interindividual differences in breeding success,and highlight the importance of underexplored research problems in avian breeding biology.
文摘When incompletely isolated taxa coexist in a patchy environment （e.g. mosaic hybrid zones, host-race complexes）, patterns of variation may differ between selected traits/genes and neutral markers. While the genetic structure of selected traits/loci tends to coincide with habitat variables （producing Genetic-Environment Association or GEA）, genetic differentiation at neutral loci unlinked to any selected locus rather depends on geographic connectivity at a large scale （e.g. Isolation- By-Distance or IBD）, although these loci often display GEA at a small scale. This discrepancy has been repeatedly taken as evi- dence for parallel primary divergence driven by local adaptation. We argue that this interpretation needs to be addressed more thoroughly by considering the alternative hypothesis that speciation was initiated in allopatry and secondary introgression has subsequently erased the signal of past differentiation at neutral loci. We present a model of neutral introgression after secondary contact in a mosaic hybrid zone, which describes how GEAs dissipate with time and how neutral variation self-organizes accord- ing to the environmental and geographic structures. We show that although neutral loci can be affected by environmental selection they are often more affected by history and connectivity： the neutral structure retains the initial geographic separation more than it correlates with the environment during the colonization and introgression phases, and then converges to a migration-drift balance, the most frequent outcome of which is GEA at a local scale but IBD at a large scale. This is the exact pattern usually attributed to parallel ecological speciation. Introgression is heterogeneous in space and depends on the landscape structure （e.g. it is faster in small patches, which are more impacted by immigration）. Furthermore, there is no directionality in the association and it is possi- ble to observe reversed GEAs between distant regions. We argue that the history of differentiation should ideally be reconstructed with selected loci or neutral loci linked to them, not neutral ones, and review some case studies for which the hypothesis of a long co-existence of co-adapted genetic backgrounds might have been refuted too hastily [Current Zoology 59 （1）： 72-86, 2013].
文摘The expanding scale and increasing rate of marine biological invasions have been documented since the early 20th century. Besides their global ecological and economic impacts, non-indigenous species （NIS） also have attracted much attention as opportunities to explore important eco-evolutionary processes such as rapid adaptation, long-distance dispersal and range expansion, and secondary contacts between divergent evolutionary lineages. In this context, genetic tools have been extensively used in the past 20 years. Three important issues appear to have emerged from such studies. First, the study of NIS has revealed unexpected cryptic diversity in what had previously been assumed homogeneous entities. Second, there has been surprisingly little evidence of strong founder events accompanying marine introductions, a pattern possibly driven by large propagule loads. Third, the evolutionary processes leading to successful invasion have been difficult to ascertain due to faint genetic signals. Here we explore the potential of novel tools associated with high-throughput sequencing （HTS） to address these still pressing issues. Dramatic increase in the number of loci accessible via HTS has the potential to radically increase the power of analyses aimed at species delineation, exploring the population genomic consequences of range expansions, and examining evolutionary processes such as admixture, introgression, and adaptation. Nevertheless, the value of this new wealth of genomic data will ultimately depend on the ability to couple it with expanded ＂traditional＂ efforts, including exhaustive sampling of marine populations over large geographic scales, integrated taxonomic analyses, and population level exploration of quantitative trait differentiation through common-garden and other laboratory experiments.
基金supported by the National Science Foundation of America(DEB-0743406)the OU VP for Research Faculty Investment Program.
文摘Evaluating the fitness of hybrids can provide important insights into genetic differences between species or diverging populations.We focused on surface-and cave-ecotypes of the widespread Atlantic molly Poecilia mexicana and raised F1 hybrids of reciprocal crosses to sexual maturity in a common-garden experiment.Hybrids were reared in a fully factorial 2 x 2 design consisting of lighting(light vs.darkness)and resource availability(high vs.low food).We quantified survival,ability to realize their full reproductive potential(i.e.,completed maturation for males and 3 consecutive births for females)and essential life-history traits.Compared to the performance of pure cave and surface fish from a previous experiment,F1s had the highest death rate and the lowest proportion of fish that reached their full reproductive potential.We also uncovered an intriguing pattern of sex-specific phenotype expression,because male hybrids expressed cave molly life histories,while female hybrids expressed surface molly life histories.Our results provide evidence for strong selection against hybrids in the cave molly system,but also sug-gest a complex pattern of sex-specific(opposing)dominance,with certain surface molly genes being dominant in female hybrids and certain cavemollygenes beingdominant in malehybrids.
文摘Reproductive traits are central to organismal fitness,and so the factors influencing patterns of reproduction and offspring survival are at the heart of biology.Making use of breeding data collected over 16 years at the King Khalid Wildlife Research Centre in Saudi Arabia,we investigated the reproductive biology of Arabian gazelles Gazella arabica.Offspring survival was mainly a function of birth weight,with heavier offspring having higher survival rates than lighter offspring.However,while sons were heavier than daughters,daughters had higher survival rates.We could not find evidence that giving birth to sons negatively impacts offspring weight in the following year.We uncovered large narrow-sense heritability(h2)in offspring weight at birth,while maternal effects(m2)on birth weight were of lesser importance.However,maternal effects on offspring survival were strong until weaning age,while paternal effects dominated survival to sexual maturity and first reproduction.We propose that variation in maternal postnatal care might overshadow the effects of maternal inheritance of birth weights,while the overall strong heritability of weight at birth and the paternal effects on survival llustrates strong variance in sire fitness based on genetic quality,suggesting a role for sexual selectionbyfemalemate choiceinwildpopulations.
文摘This study endeavour assesses agromorphological likeness between initial introductions and regenerated accessions at the International Coconut Genebank for Africa and the Indian Ocean (ICG-AIO) based in C?te d’Ivoire. Ten couples of parental (G0) and regenerated (G1) accessions of Tall coconut palms were analyzed using Principal Component Analysis (PCA) and Multiple Analysis of Variance (MANOVA) from 26 agromorphological characters. The main results showed a relative decrease in the expression of the phenotypical traits concerning the component of the fruit, height and vigor of the stem and yield of bunches and fruits after one regeneration cycle. But, a high proportion (69%) of studied characters from leaf, inflorescence and nut components showed likeness between G0 and G1 accessions. After one regeneration cycle, the controlled pollination method guarantees significant conservation of the expression of the majority of agromorphological traits. Consequently, regenerated accessions of Tall coconut palms can be used to pursue research and development programs in C?te d’Ivoire.
文摘Soil organic matter (SOM) is a complex heterogeneous mixture formed through decomposition and organo-mineral interactions, and characterization of its composition and biogeochemical stability is challenging. From this perspective, Rock-Eval® is a rapid and efficient thermal analytical method that combines the quantitative and qualitative information of SOM, including several parameters related to thermal stability. This approach has already been used to monitor changes in organic matter (OM) properties at the landscape, cropland, and soil profile scales. This study was aimed to assess the stability of SOM pools by characterizing the grain size fractions from forest litters and topsoils using Rock-Eval® thermal analysis. Litter (organic) and topsoil samples were collected from a beech forest in Normandy (France), whose management in the last 200 years has been documented. Fractionation by wet sieving was used to separate large debris (> 2 000 μm) and coarse (200–2 000 μm) and fine particulate OM (POM) (50–200 μm) in the organic samples as well as coarse (200–2 000 μm), medium (50–200 μm), and fine (< 50 μm) fractions of the topsoil samples. Rock-Eval® was able to provide thermal parameters sensitive enough to study fine-scale soil processes. In the organic layers, quantitative and qualitative changes were explained by the progressive decomposition of labile organic compounds from plant debris to the finest organic particles. Meanwhile, the grain size fractions of topsoils presented different characteristics. The coarse organo-mineral fractions showed higher C contents, albeit with a different composition, higher thermal stability, and greater decomposition degree than the plant debris forming the organic layer. These results are consistent with those of previous studies that microbial activity is more effective in this fraction. The finest fractions of topsoils showed low C contents, the highest thermal stability, and low decomposition degree, which can be explained by the stronger interactions with the mineral matrix. Therefore, it is suggested that the dynamics of OM in the different size fractions be interpreted in the light of a plant-microbe-soil continuum. Finally, three distinct thermostable C pools were highlighted through the grain size heterogeneity of SOM: free coarse OM (large debris and coarse and fine particles), weakly protected OM in (bio)aggregates (coarse fraction of topsoil), and stabilized OM in the fine fractions of topsoil, which resulted from the interactions within organo-mineral complexes. Therefore, Rock-Eval® thermal parameters can be used to empirically illustrate the conceptual models emphasizing the roles of drivers played by the gradual decomposition and protection of the most thermally labile organic constituents.
基金supported by the ANR (French National Agency of Research, JASSUR research project ANR-12-VBDU-0011)
文摘Geogenic lead (Pb) is considered to be less bioavailable than anthropogenic Pb and exerts less effect on the soil fauna. However,Pb contamination in vegetables has been reported in the case of geogenic anomalies, even at moderate concentrations (around 170 mgkg^(-1)). In this study, we investigated collembolan communities using both taxonomic- and trait-based approaches and observed fungal communities to assess the effects of a moderate geogenic Pb anomaly on collembolans and fungi in an urban vegetable garden soil.Results indicated that geogenic Pb indeed modified fungi communities and altered the functional structure of collembolan communities in garden soils. Although geogenic Pb presented low bioavailability, it affected soil fauna and vegetables similar to anthropogenic Pb.
基金the National Swedish Research Council(grants No.2015-04402,2019-04486)the Carl Trygger Foundation(CTS 20:6)+3 种基金the Jornvall FoundationJulian Francis for financial supportthe National Genomics Infrastructure in Stockholm funded by Science for Life Laboratory,the Knut and Alice Wallenberg Foundationthe Research/Scientific Computing teams at The James Hutton Institute and NIAB for providing computational resources and technical support for the"UK's Crop Diversity Bioinformatics HPC"(BBSRC grant BB/S019669/1)。
文摘The family Alaudidae,larks,comprises 93-100 species(depending on taxonomy)that are widely distributed across Africa and Eurasia,with single species extending their ranges to North and northernmost South America and Australia.A decade-old molecular phylogeny,comprising~80%of the species,revealed multiple cases of parallel evolution and large variation in rates of morphological evolution,which had misled taxonomists into creating many non-monophyletic genera.Here,we reconstruct the phylogeny of the larks,using a dataset covering one mitochondrial and 16 nuclear loci and comprising all except one of the currently recognised species as well as several recently proposed new species(in total 133 taxa;not all loci available for all species).We provide additional support using genome-wide markers to infer a genus-level phylogeny based on near-complete generic sampling(in total 51 samples of 44 taxa across 40 species).Our results confirm the previous findings of rampant morphological convergence and divergence,and reveal new cases of paraphyletic genera.We propose a new subfamily classification,and also that the genus Mirafra is divided into four genera to produce a more balanced generic classification of the Alaudidae.Our study supports recently proposed species splits as well as some recent lumps,while also questioning some of the latter.This comprehensive phylogeny will form an important basis for future studies,such as comparative studies of lark natural history,ecology,evolution and conservation.
基金supported bythe NationalNatural Science Foundation of China(32171609,32261123001)to X.-Y.C.
文摘Closely related and co-distributed species usually share a common phylogeographic history,but it remains unclear whether ecologically interacting species can respond synchronously to historical climate changes.Here,we focused on a fig-pollinator mutualism comprising Ficus pumila var.pumila and its obligate pollinators(morphospecies Wiebesia pumilae),and collected samples across most of their distribution ranges.We employed cytoplasmic DNA sequences and nuclear microsatellite loci to reveal the species composition within the pollinators and to test whether the two mutualists exhibited similar postglacial phylogeographic patterns.We identified three cryptic pollinator species,with two dominant cryptic species exhibiting parapatric distributions in the northern and southern parts of the plant's range,respectively.Similar current spatial genetic structures were detected in the two dominant cryptic pollinator species and the host plant,with both showing eastern and western genetic clusters.Moreover,evidence for postglacial expansion was found for all three species,and their potential refugia during the Last Glacial Maximum were located in the eastern and western parts of their distribution ranges.These results suggest synchronous responses to historical climate changes.Our study demonstrates congruent phylogeographic patterns between obligate mutualists and highlights the role of biogeographic factors in shaping the current biodiversity across trophic levels.
基金supported by a grant of the 1551 French-Thai cooperation PHC SIAM 2011(project 25587RA)the grants“Taxonomy,Phylogeny and cultivation of Lentinus species in northern Thailand”(MFU/54101020048)+1 种基金from Mae Fah Luang University research division and financially supported by the project“Value added products from basidiomycetes:Putting Thailand’s biodiversity to use”(BRN049/2553)the National Research Council of Thailand(NRCT)to study medicinal fungi.
文摘Diabetes mellitus is a life-threatening chronic metabolic disease caused by lack of insulin and/or insulin dysfunction,characterized by high levels of glucose in the blood(hyperglycemia).Millions worldwide suffer from diabetes and its complications.Significantly,it has been recognized that type 2 diabetes is an important preventable disease and can be avoided or delayed by lifestyle intervention.Presently,there are many chemical and biochemical hypoglycemic agents(synthetic drugs),that are used in treating diabetes and are effective in controlling hyperglycemia.However,as they may have harmful side-effects and fail to significantly alter the course of diabetic complications,natural anti-diabetic drugs from medicinal plants have attracted a great deal of attention.Medicinal mushrooms have been valued as a traditional source of natural bioactive compounds over many centuries and have been targeted as potential hypoglycemic and anti-diabetic agents.Bioactive metabolites including polysaccharides,proteins,dietary fibres,and many other biomolecules isolated from medicinal mushrooms and their cultured mycelia have been shown to be successful in diabetes treatment as biological antihyperglycemic agents.In this review we discuss the biological nature of diabetes and,in particular,explore some promising mushrooms that have experimental anti-diabetic properties,preventing or reducing the development of diabetes mellitus.The importance of medicinal mushrooms as agents of medical nutrition therapy and how their metabolites can be used as supportive candidates for prevention and control of diabetes is explored.Future prospects for this field of study and the difficulties and constraints that might affect the development of rational drug products from medicinal mushrooms are discussed.
基金This research was supported by the Spanish Ministries of Science,Innovation and Universities(FPU grant FPU17/00629 awarded to R.S.M.)and of Economy and Competitiveness(grant CGL2016-79950-R)including FEDER fundsby the Junta de Andalucfa/FP7 Talentia program.
文摘Aims Dispersal through space or time via dormancy is one of the primary processes whereby organisms can influence the environment they experience.In plants,strong evolutionary correlations are expected between the two kinds of dispersal because both are performed by the seeds and play comparable adaptive roles.In this paper,we investigated these evolutionary correlations using amphicarpic plants,which simultaneously produce aerial seeds with high spatial dispersal propensity and subterranean seeds that do not disperse.Methods We investigated the variation in dormancy and germination in aerial and subterranean seeds of two amphicarpic legumes(Vicia amphicarpa L.and Lathyrus amphicarpos L.)and two closely related homocarpic taxa(Vicia sativa L.and Lathyrus cicera L.)by estimating germination percentages following different combinations of dormancy breaking treatments(i.e.dry after-ripening,cold stratification and physical scarification).Important Findings Our results showed complex interactions between spatial and temporal dispersal.Right after dispersal,aerial seeds were more dormant than their subterranean counterparts,but this trend reversed with after-ripening,as seeds developed physical dormancy.Seeds of homocarpic plants germinated at higher percentages than those of their amphicarpic congeners and lost dormancy homogeneously with after-ripening.Conversely,amphicarpic seeds exhibited varied dormancy strategies modulated by both physiological and physical dormancy.These are expected to increase variation in emergence timing,providing multiple levels of diversifying bet-hedging.This strategy might be adaptive under highly unpredictable conditions by enabling plants to rely on historically favorable sites in good seasons without preventing spatial and temporal migration.
基金supported by a grant of the French-Thai cooperation PHC SIAM 2011(project 25587RA).
文摘Medicinal mushrooms have been valued as natural sources of bioactive compounds since times immemorial and have been recognized as potential immunomodulating and anti-cancer agents.Their consumption has consistently been shown to have beneficial effects on human health.Cancer is a generic term for several types of diseases that can be chronic and are responsible for a large number of deaths worldwide.Although there has been considerable progress in modern cancer therapy research,difficulties in understanding the molecular behavior of various types of cancers and the numerous side effects experienced by patients from treatments means that this whole subject area is still problematic.Thus,biological immunotherapy using natural bioactive compounds as supportive treatments in conventional cancer therapies has become in vogue.Bioactive metabolites isolated from medicinal mushrooms have shown potential successes in cancer treatment as biological immunotherapeutic agents that stimulate the immune system against cancer cells.They also act as an effective source of anti-cancer agents,capable of interfering with cellular signal transduction pathways linked to cancer development and progression.In this review we compile available data on the characteristics of medicinal mushrooms that appear to be particularly effective as biological immunotherapeutic agents.Major consideration is given to biological constituents and the putative mechanisms of action by which bioactive compounds act on the human body.Consideration is also given to the benefits that have been claimed for the use of mushrooms in treating cancer and the future prospects of using medicinal mushrooms as potent supportive candidate bioagents for treatment of cancers is discussed.
基金This work was partly supported by the European Union 7th Framework project REFRESH under contract no.244121.
文摘Aims For temperate regions such as Northern Europe,predicted climate change patterns include an increase in winter precipitation causing increased risk of flooding,whereas periods of droughts will become more frequent in summer.The aim of this study is to explore vari-ations in plant functional trait distributions along a hydrological gradient spanning from recurrent drought events to recurrent flood-ing-mimicking future precipitation patterns.Methods The experiment was conducted in a controlled grassland experi-ment over a period of 3 years.A novel and more extreme hydro-logical regime was achieved by manipulating the flow of a nearby stream thereby creating a continuous hydrological gradient from flooding during winter to drought during summer.Plant commu-nity responses were recorded along this hydrological gradient.Community-weighted trait distribution changes along the gradient were described using null models.Six functional traits were con-sidered:seed mass,leaf dry matter content(LDMC),leaf area,leaf thickness,specific leaf area(SLA)and height.Important findings Over time,responses in plant functional traits changed at the community level.Over the study period consistent changes occurred in the mean trait value of several traits.Communities in relatively dry plots became dominated by species with water-conserving life strategies,represented by high seed mass and thick leaves.In contrast,disturbance-resistant species(high leaf dry matter content)became dominant in flooded plots,indicating that persistence to flooding was the most important factor control-ling the functional structure in those communities.Furthermore,a high abundance of small-seeded species in flooded plots likely indicates higher frequency of species with higher dispersal ability through hydrochory.In conclusion,plant traits are useful for predicting responses to climate change,but abrupt and extreme climate event may cause unexpected responses because they have no analog to previously more stable conditions.We suggest that traits related to dispersal and resistance to disturbance are useful in describing responses to flooding and that these traits should be included in future inves-tigations of plant community responses to extreme hydrological events.
基金This study was supported by the grant of the 1551 French-Thai cooperation PHC SIAM 2011(project 25587RA)and the Mae Fah Luang University funded grant“Taxonomy,Phylogeny and cultivation of Lentinus species in northern Thailand”(MFU/54101020048)this study was financially supported by the project“Value added products from basidiomycetes:Putting Thailand’s biodiversity to use”(BRN049/2553)by the National Research Council of Thailand(NRCT)to study medicinal fungi+1 种基金the National Research Council of Thailand(NRCT),project-Taxonomy,Phylogeny and cultivation of Lentinus species in northern Thailand(NRCT/55201020007)the Thailand Research Fund grant-Taxonomy,Phylogeny and biochemistry of Thai Basidiomycetes(BRG 5580009).The authors would also like to acknowledge University Malaya research grants:CG037-2013 Phylogeny,taxonomy,relationships and biotechnological potential of sooty moulds and RG203-12SUS Isolation and structural elucidation of antimicrobial compounds for saprophytic and endophytic fungi of Peninsular Malaysia through bioassay guided fractionation of secondary metabolites extract.
文摘Exploration of natural sources for novel bioactive compounds has been an emerging field of medicine over the past decades,providing drugs or lead compounds of considerable therapeutic potential.This research has provided exciting evidence on the isolation of microbe-derived metabolites having prospective biological activities.Mushrooms have been valued as traditional sources of natural bioactive compounds for many centuries and have been targeted as promising therapeutic agents.Many novel biologically active compounds have been reported as a result of research on medicinal mushrooms.In this review,we compile the information on bioactive structure-elucidated metabolites from macrofungi discovered over the last decade and highlight their unique chemical diversity and potential benefits to novel drug discovery.The main emphasis is on their anti-Alzheimer,antidiabetic,anti-malarial,anti-microbial,anti-oxidant,antitumor,anti-viral and hypocholesterolemic activities which are important medicinal targets in terms of drug discovery today.Moreover,the reader’s attention is brought to focus on mushroom products and food supplements available in the market with claimed biological activities and potential human health benefits.
基金the Thailand Science Research and Innovation grant“Macrofungi diversity research from the Lancang-Mekong Watershed and surrounding areas”(Grant No.DBG6280009)the National Research Council of Thailand(NRCT)grant“Total fungal diversity in a given forest area with implications towards species numbers,chemical diversity and biotechnology”(Grant No.N42A650547+1 种基金We thank the Mushroom Research Foundation,Chiang Rai,Thailand for supporting the Ph.D studies of A.G.Niego.Niego would like to acknowledge the Mae Fah Luang University Thesis/Dissertation Support Grant(Reference No.Oh 7702(6)/49)EC-G was supported by the HZI POF IV Cooperativity and Creativity Project Call and CL was funded by a PhD stipend of the Life Science Foundation,Munich.
文摘Fungi provide ecological and environmental services to humans, as well as health and nutritional benefits, and are vital to numerousindustries. Fermented food and beverage products from fungi are circulating in the market, generating billions of USD.However, the highest potential monetary value of fungi is their role in blue carbon trading because of their ability to sequesterlarge amounts of carbon in the soil. There are no conclusive estimates available on the global monetary value of fungi, primarilybecause there are limited data for extrapolation. This study outlines the contribution of fungi to the global economy and providesa first attempt at quantifying the global monetary value of fungi. Our estimate of USD 54.57 trillion provides a starting point thatcan be analysed and improved, highlighting the significance of fungi and providing an appreciation of their value. This paperidentifies the different economically valuable products and services provided by fungi. By giving a monetary value to all importantfungal products, services, and industrial applications underscores their significance in biodiversity and conservation. Furthermore,if the value of fungi is well established, they will be considered in future policies for effective ecosystem management.
基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences,Grant No.XDB31000000Naritsada Thongklang would like to thank Thailand research fund grants“Study of saprobic Agaricales in Thailand to find new industrial mushroom products”(Grant No.DBG6180015)+10 种基金Mae Fah Luang University grant“Optimal conditions for domestication and biological activities of selected species of Ganoderrma”(Grant No.621C1535)K.D.Hyde and Naritsada Thongklang would like to thanks to Thailand research fund grants“Domestication and bioactive evaluation of Thai Hymenopellis,Oudemansiella,Xerula and Volvariella species(basidiomycetes)”(Grant No.DBG6180033)K.D.Hyde thanks the financial support from the Visiting Professor grant at Chiang Mai University,Thailand and KIB.The authors acknowledge the contribution of M.M.Vasanthakumari,K.M.Manasa and P.Rajani,in various stages of preparation of the manuscript.Samantha C.Karunarathna thanks CAS President’s International Fellowship Initiative(PIFI)for funding his postdoctoral research(Number 2018PC0006)the National Science Foundation.Associate Professor R Jeewon thanks University of Mauritius for support.Binu C.Samarakoon offers her sincere gratitude to the“National Research Council of Thailand”(NRCT Grant No.256108A3070006)for the financial supportPeter E Mortimer would like to thank the National Science Foundation of China and the Chinese Academy of Sciences for financial support under the following Grants:41761144055,41771063,Y4ZK111B01M.Doilom would like to thank Chiang Mai University,the 5th batch of Postdoctoral Orientation Training Personnel in Yunnan Province and the 64th batch of China Postdoctoral Science Foundation.T.S.Suryanarayanan thanks the United States-India Educational Foundation(USIEF)New Delhi and the Fulbright Scholar Program(USA)for the award of a Fulbright-Nehru Senior Researcher grant to conduct research in the Department of Chemistry and Biochemistry,The Ohio State University,USA.Thanks to Research and Researchers for Industries Grant(PHD57I0015)for financial support to Boontiya Chuankid.Birthe Sandargo is grateful to the Deutsche Forschungsgemeinschaft(DFG)for a PhD grant.Clara Chepkirui is indebted to a PhD stipend from the German Academic Exchange Service(DAAD)and the Kenya National Council for Science and Technology(NACOSTI)Kevin D Hyde would also like to thank the National Research Council of Thailand grants Thailands’Fungal Diversity,Solving Problems and Creating Biotechnological Products(Grant No.61201321016)This work is partly supported by the Department of Biotechnology,Government of India,New Delhi(Chemical Ecology of the North East Region(NER)of India:A collaborative programme Linking NER and Bangalore ResearchersDBT-NER/Agri/24/2013)and Indian Council of Agricultural Research(ICAR-CAAST-Project F.No./NAHEP/CAAST/2018-19)Government of India,New Delhi.
文摘Fungi are an understudied,biotechnologically valuable group of organisms.Due to the immense range of habitats that fungi inhabit,and the consequent need to compete against a diverse array of other fungi,bacteria,and animals,fungi have developed numerous survival mechanisms.The unique attributes of fungi thus herald great promise for their application in biotechnology and industry.Moreover,fungi can be grown with relative ease,making production at scale viable.The search for fungal biodiversity,and the construction of a living fungi collection,both have incredible economic potential in locating organisms with novel industrial uses that will lead to novel products.This manuscript reviews fifty ways in which fungi can potentially be utilized as biotechnology.We provide notes and examples for each potential exploitation and give examples from our own work and the work of other notable researchers.We also provide a flow chart that can be used to convince funding bodies of the importance of fungi for biotechnological research and as potential products.Fungi have provided the world with penicillin,lovastatin,and other globally significant medicines,and they remain an untapped resource with enormous industrial potential.
文摘This article is the 14th in the Fungal Diversity Notes series,wherein we report 98 taxa distributed in two phyla,seven classes,26 orders and 50 families which are described and illustrated.Taxa in this study were collected from Australia,Brazil,Burkina Faso,Chile,China,Cyprus,Egypt,France,French Guiana,India,Indonesia,Italy,Laos,Mexico,Russia,Sri Lanka,Thailand,and Vietnam.There are 59 new taxa,39 new hosts and new geographical distributions with one new combination.The 59 new species comprise Angustimassarina kunmingense,Asterina lopi,Asterina brigadeirensis,Bartalinia bidenticola,Bartalinia caryotae,Buellia pruinocalcarea,Coltricia insularis,Colletotrichum fexuosum,Colletotrichum thasutense,Coniochaeta caraganae,Coniothyrium yuccicola,Dematipyriforma aquatic,Dematipyriforma globispora,Dematipyriforma nilotica,Distoseptispora bambusicola,Fulvifomes jawadhuvensis,Fulvifomes malaiyanurensis,Fulvifomes thiruvannamalaiensis,Fusarium purpurea,Gerronema atrovirens,Gerronema favum,Gerronema keralense,Gerronema kuruvense,Grammothele taiwanensis,Hongkongmyces changchunensis,Hypoxylon inaequale,Kirschsteiniothelia acutisporum,Kirschsteiniothelia crustaceum,Kirschsteiniothelia extensum,Kirschsteiniothelia septemseptatum,Kirschsteiniothelia spatiosum,Lecanora immersocalcarea,Lepiota subthailandica,Lindgomyces guizhouensis,Marthe asmius pallidoaurantiacus,Marasmius tangerinus,Neovaginatispora mangiferae,Pararamichloridium aquisubtropicum,Pestalotiopsis piraubensis,Phacidium chinaum,Phaeoisaria goiasensis,Phaeoseptum thailandicum,Pleurothecium aquisubtropicum,Pseudocercospora vernoniae,Pyrenophora verruculosa,Rhachomyces cruralis,Rhachomyces hyperommae,Rhachomyces magrinii,Rhachomyces platyprosophi,Rhizomarasmius cunninghamietorum,Skeletocutis cangshanensis,Skeletocutis subchrysella,Sporisorium anadelphiae-leptocomae,Tetraploa dashaoensis,Tomentella exiguelata,Tomentella fuscoaraneosa,Tricholomopsis lechatii,Vaginatispora favispora and Wetmoreana blastidiocalcarea.The new combination is Torula sundara.The 39 new records on hosts and geographical distribution comprise Apiospora guiyangensis,Aplosporella artocarpi,Ascochyta medicaginicola,Astrocystis bambusicola,Athelia rolfsii,Bambusicola bambusae,Bipolaris luttrellii,Botryosphaeria dothidea,Chlorophyllum squamulosum,Colletotrichum aeschynomenes,Colletotrichum pandanicola,Coprinopsis cinerea,Corylicola italica,Curvularia alcornii,Curvularia senegalensis,Diaporthe foeniculina,Diaporthe longicolla,Diaporthe phaseolorum,Diatrypella quercina,Fusarium brachygibbosum,Helicoma aquaticum,Lepiota metulispora,Lepiota pongduadensis,Lepiota subvenenata,Melanconiella meridionalis,Monotosporella erecta,Nodulosphaeria digitalis,Palmiascoma gregariascomum,Periconia byssoides,Periconia cortaderiae,Pleopunctum ellipsoideum,Psilocybe keralensis,Scedosporium apiospermum,Scedosporium dehoogii,Scedosporium marina,Spegazzinia deightonii,Torula fci,Wiesneriomyces laurinus and Xylaria venosula.All these taxa are supported by morphological and multigene phylogenetic analyses.This article allows the researchers to publish fungal collections which areimportant for future studies.An updated,accurate and timely report of fungus-host and fungus-geography is important.We also provide an updated list of fungal taxa published in the previous fungal diversity notes.In this list,erroneous taxa and synonyms are marked and corrected accordingly.
