Ochratoxin-A[7-(L-β-phenylalanylcarbonyl)-carboxyl-5-chloro-8-hydroxy-3,4-dihydro-3R-methyl-isocumarin, OTA] is a common food contaminant mycotoxin that enters the human body through the consumption of improperly sto...Ochratoxin-A[7-(L-β-phenylalanylcarbonyl)-carboxyl-5-chloro-8-hydroxy-3,4-dihydro-3R-methyl-isocumarin, OTA] is a common food contaminant mycotoxin that enters the human body through the consumption of improperly stored food products. Upon ingestion, it leads to immuno-suppression and immuno-toxicity. OTA has been known to produce nephrotoxic, teratogenic, and carcinogenic activity (via oxidative DNA damage) in several species. This review introduces potentials of electrochemical biosensor to provide breakthroughs in OTA detection through improved selectivity and sensitivity and also the current approaches for detecting OTA in food products.展开更多
This paper presents the development of a Twin-T oscillator comprising polymer coated parallel plates as a sensor for ocean water salinity monitoring.This sensor employs a parallel plate capacitor design, with sea wate...This paper presents the development of a Twin-T oscillator comprising polymer coated parallel plates as a sensor for ocean water salinity monitoring.This sensor employs a parallel plate capacitor design, with sea water serving as the medium between plates. Novalac resin and a proprietary commercial polymer (AccufloTW) were investigated as corrosion protective coatings for the copper electrodes of the capacitor. Electrochemical Impedance Spectroscopy (EIS) was employed to evaluate corrosion inhibition of polymer coatingin sea water. A detection circuit was designed and simulated using P-spice and then implemented in Printed Circuit Board (PCB). EIS results indicate that Accuflo exhibits better corrosion inhibition in ocean water than Novolac. Further, the use of Twin-T oscillator based detection circuit resulted in enhanced sensitivity and better detection limit. Experiments performed using ocean water samples resulted in oscillator frequency shift of 410 Hertz/power supply unit (Hz/PSU). Oscillator frequency drift was reduced using frequency-to-voltage converters and sensitivity of 10 mV/PSU was achieved.展开更多
文摘Ochratoxin-A[7-(L-β-phenylalanylcarbonyl)-carboxyl-5-chloro-8-hydroxy-3,4-dihydro-3R-methyl-isocumarin, OTA] is a common food contaminant mycotoxin that enters the human body through the consumption of improperly stored food products. Upon ingestion, it leads to immuno-suppression and immuno-toxicity. OTA has been known to produce nephrotoxic, teratogenic, and carcinogenic activity (via oxidative DNA damage) in several species. This review introduces potentials of electrochemical biosensor to provide breakthroughs in OTA detection through improved selectivity and sensitivity and also the current approaches for detecting OTA in food products.
文摘This paper presents the development of a Twin-T oscillator comprising polymer coated parallel plates as a sensor for ocean water salinity monitoring.This sensor employs a parallel plate capacitor design, with sea water serving as the medium between plates. Novalac resin and a proprietary commercial polymer (AccufloTW) were investigated as corrosion protective coatings for the copper electrodes of the capacitor. Electrochemical Impedance Spectroscopy (EIS) was employed to evaluate corrosion inhibition of polymer coatingin sea water. A detection circuit was designed and simulated using P-spice and then implemented in Printed Circuit Board (PCB). EIS results indicate that Accuflo exhibits better corrosion inhibition in ocean water than Novolac. Further, the use of Twin-T oscillator based detection circuit resulted in enhanced sensitivity and better detection limit. Experiments performed using ocean water samples resulted in oscillator frequency shift of 410 Hertz/power supply unit (Hz/PSU). Oscillator frequency drift was reduced using frequency-to-voltage converters and sensitivity of 10 mV/PSU was achieved.
