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Big Data Research in Italy: A Perspective 被引量:1
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作者 Sonia Bergamaschi Emanuele Carlini +9 位作者 Michelangelo Ceci Barbara Furletti Fosca Giannotti Donato Malerba Mario Mezzanzanica Anna Monreale Gabriella Pasi Dino Pedreschi Raffele Perego Salvatore Ruggieri 《Engineering》 SCIE EI 2016年第2期163-170,共8页
The aim of this article is to synthetically describe the research projects that a selection of Italian univer- sities is undertaking in the context of big data. Far from being exhaustive, this article has the objectiv... The aim of this article is to synthetically describe the research projects that a selection of Italian univer- sities is undertaking in the context of big data. Far from being exhaustive, this article has the objective of offering a sample of distinct applications that address the issue of managing huge amounts of data in Italy, collected in relation to diverse domains. 展开更多
关键词 Big data Smart cities EnergyJob offersPrivacy
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Victimization Risk Identification Based on Fingerprint Features of Fraudulent Website
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作者 Zhou Shengli Shen Xinyan +2 位作者 Xu Rui Wang Zhenbo Yang Chaoyi 《China Communications》 2025年第10期199-213,共15页
Fraudulent website is an important car-rier tool for telecom fraud.At present,criminals can use artificial intelligence generative content technol-ogy to quickly generate fraudulent website templates and build fraudul... Fraudulent website is an important car-rier tool for telecom fraud.At present,criminals can use artificial intelligence generative content technol-ogy to quickly generate fraudulent website templates and build fraudulent websites in batches.Accurate identification of fraudulent website will effectively re-duce the risk of public victimization.Therefore,this study developed a fraudulent website template iden-tification method based on DOM structure extraction of website fingerprint features,which solves the prob-lems of single-dimension identification,low accuracy,and the insufficient generalization ability of current fraudulent website templates.This method uses an im-proved SimHash algorithm to traverse the DOM tree of a webpage,extract website node features,calcu-late the weight of each node,and obtain the finger-print feature vector of the website through dimension-ality reduction.Finally,the random forest algorithm is used to optimize the training features for the best combination of parameters.This method automati-cally extracts fingerprint features from websites and identifies website template ownership based on these features.An experimental analysis showed that this method achieves a classification accuracy of 89.8%and demonstrates superior recognition. 展开更多
关键词 fraudulent website improved SimHash algorithm multi-class classification victimization risk identification website fingerprinting
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Enhancing energy security through efficient decarbonization:Impact of China’s“Constructing Large Units and Restricting Small Ones”policy on thermal power productivity
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作者 Jinsong Zhao Chin-Hsien Yu Xinghao Li 《Chinese Journal of Population,Resources and Environment》 2025年第2期168-180,共13页
Developing low-carbon and efficient power systems is critical for energy security in the global warming context.We address this issue by focusing on the productivity impact of a decarbonization policy in China’s ther... Developing low-carbon and efficient power systems is critical for energy security in the global warming context.We address this issue by focusing on the productivity impact of a decarbonization policy in China’s thermal power sector—namely,the“Constructing Large Units and Restricting Small Ones”(CLRS)initiative.Utilizing a resource misallocation model,we construct a new theoretical framework to distinguish between technical and allocative efficiency and analyze productivity using plant-level data.The results indicate that the CLRS policy has significantly improved the allocative and technical efficiency of China’s coal-fired power sector,thereby ensuring power security.The closure of outdated and highly distorted small coal-fired units,which have been replaced by technologically advanced large units,primarily drives the enhanced efficiency.The policy’s effects are most pronounced in large-scale power plants and those with high coal combustion efficiency.Furthermore,a comparison of power plants’productivity distribution before and after policy implementation reveals that the CLRS policy not only enhances capital productivity in the coal-fired power sector but also increases rational labor allocation.Our findings have important policy implications for developing countries vis-à-vis building efficient and stable power systems amid climate change. 展开更多
关键词 Decarbonization policy Energy security Thermal power Technical efficiency Resource allocative efficiency
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TCMHTI:a Transformer-based herb-target interaction prediction model for Qingfu Juanbi Decoction in rheumatoid arthritis
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作者 Zhenzhong LIANG Changsong DING 《Digital Chinese Medicine》 2025年第2期206-218,共13页
Objective To predict the potential targets of Qingfu Juanbi Decoction(青附蠲痹汤,QFJBD)in treating rheumatoid arthritis(RA)using an improved Transformer model and investigate the network pharmacological mechanisms und... Objective To predict the potential targets of Qingfu Juanbi Decoction(青附蠲痹汤,QFJBD)in treating rheumatoid arthritis(RA)using an improved Transformer model and investigate the network pharmacological mechanisms underlying QFJBD’s therapeutic effects on RA.Methods First,a traditional Chinese medicine herb-target interaction(TCMHTI)model was constructed to predict herb-target interactions based on Transformer improvement.The per-formance of the TCMHTI model was evaluated against baseline models using three metrics:area under the receiver operating characteristic curve(AUC),precision-recall curve(PRC),and accuracy.Subsequently,a protein-protein interaction(PPI)network was built based on the predicted targets,with core targets identified as the top nine nodes ranked by degree val-ues.Gene Ontology(GO)functional and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment analyses were performed using the targets predicted by TCMHTI and the targets identified through network pharmacology method for comparison.Then,the re-sults were compared.Finally,the core targets predicted by TCMHTI were validated through molecular docking and literature review.Results The TCMHTI model achieved an AUC of 0.883,PRC of 0.849,and accuracy of 0.818,predicting 49 potential targets for QFJBD in RA treatment.Nine core targets were identified:tumor necrosis factor(TNF)-α,interleukin(IL)-1β,IL-6,IL-10,IL-17A,cluster of differentia-tion 40(CD40),cytotoxic T-lymphocyte-associated protein 4(CTLA4),IL-4,and signal trans-ducer and activator of transcription 3(STAT3).The enrichment analysis demonstrated that the TCMHTI model predicted 49 targets and enriched more pathways directly associated with RA,whereas classical network pharmacology identified 64 targets but enriched pathways showing weaker relevance to RA.Molecular docking demonstrated that the active molecules in QFJBD exhibit favorable binding energy with RA targets,while literature research further revealed that QFJBD can treat RA through 9 core targets.Conclusion The TCMHTI model demonstrated greater accuracy than traditional network pharmacology methods,suggesting QFJBD exerts therapeutic effects on RA by regulating tar-gets like TNF-α,IL-1β,and IL-6,as well as multiple signaling pathways.This study provides a novel framework for bridging traditional herbal knowledge with precision medicine,offering actionable insights for developing targeted TCM therapies against diseases. 展开更多
关键词 Transformer Qingfu Juanbi Decoction Rheumatoid arthritis Deep learning Network pharmacology
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Impact of Extreme Pacific-Japan Teleconnection Patterns on Tropical Cyclone Activity around Far East Asia
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作者 Minkyu LEE Dong-Hyun CHA +4 位作者 Haeun JO Woojin CHO Seung-Ki MIN Doo-Sun R Joowan KIM 《Advances in Atmospheric Sciences》 2025年第11期2263-2278,共16页
This study identified the relationship between tropical cyclone(TC)activity and extreme Pacific–Japan(PJ)teleconnection patterns in August and September.In the East China Sea(ECS)and Mariana Islands(MI)regions,where ... This study identified the relationship between tropical cyclone(TC)activity and extreme Pacific–Japan(PJ)teleconnection patterns in August and September.In the East China Sea(ECS)and Mariana Islands(MI)regions,where the edge of the western North Pacific subtropical high(WNPSH)is located,approximately 60%–75%of TCs migrate to Far East Asian countries.A significant positive correlation existed between the frequency of northward migration of TCs and PJ patterns,since the TC frequency in the ECS and MI regions was significantly higher in the positive compared with the negative phase.In the positive phase,the main reason for the large number of TCs occurring was the monsoon trough’s location and strength.The strong and northeastward-shifted monsoon trough in the positive phase leads to more TCs in the ECS and MI regions.Other large-scale environments associated with TC formation also favored TC genesis around the ECS and MI regions.The higher PDI(power dissipation index)during the positive PJ phase can potentially lead to significant impacts in the Far East Asian countries.These characteristics were particularly more notable in August compared with September. 展开更多
关键词 tropical cyclone Pacific–Japan teleconnection pattern Far East Asia monsoon trough large-scale environment
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Image Recognition Model of Fraudulent Websites Based on Image Leader Decision and Inception-V3 Transfer Learning 被引量:1
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作者 Shengli Zhou Cheng Xu +3 位作者 Rui Xu Weijie Ding Chao Chen Xiaoyang Xu 《China Communications》 SCIE CSCD 2024年第1期215-227,共13页
The fraudulent website image is a vital information carrier for telecom fraud.The efficient and precise recognition of fraudulent website images is critical to combating and dealing with fraudulent websites.Current re... The fraudulent website image is a vital information carrier for telecom fraud.The efficient and precise recognition of fraudulent website images is critical to combating and dealing with fraudulent websites.Current research on image recognition of fraudulent websites is mainly carried out at the level of image feature extraction and similarity study,which have such disadvantages as difficulty in obtaining image data,insufficient image analysis,and single identification types.This study develops a model based on the entropy method for image leader decision and Inception-v3 transfer learning to address these disadvantages.The data processing part of the model uses a breadth search crawler to capture the image data.Then,the information in the images is evaluated with the entropy method,image weights are assigned,and the image leader is selected.In model training and prediction,the transfer learning of the Inception-v3 model is introduced into image recognition of fraudulent websites.Using selected image leaders to train the model,multiple types of fraudulent websites are identified with high accuracy.The experiment proves that this model has a superior accuracy in recognizing images on fraudulent websites compared to other current models. 展开更多
关键词 fraudulent website image leaders telecom fraud transfer learning
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Adaptive Successive POI Recommendation via Trajectory Sequences Processing and Long Short-Term Preference Learning
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作者 Yali Si Feng Li +3 位作者 Shan Zhong Chenghang Huo Jing Chen Jinglian Liu 《Computers, Materials & Continua》 SCIE EI 2024年第10期685-706,共22页
Point-of-interest(POI)recommendations in location-based social networks(LBSNs)have developed rapidly by incorporating feature information and deep learning methods.However,most studies have failed to accurately reflec... Point-of-interest(POI)recommendations in location-based social networks(LBSNs)have developed rapidly by incorporating feature information and deep learning methods.However,most studies have failed to accurately reflect different users’preferences,in particular,the short-term preferences of inactive users.To better learn user preferences,in this study,we propose a long-short-term-preference-based adaptive successive POI recommendation(LSTP-ASR)method by combining trajectory sequence processing,long short-term preference learning,and spatiotemporal context.First,the check-in trajectory sequences are adaptively divided into recent and historical sequences according to a dynamic time window.Subsequently,an adaptive filling strategy is used to expand the recent check-in sequences of users with inactive check-in behavior using those of similar active users.We further propose an adaptive learning model to accurately extract long short-term preferences of users to establish an efficient successive POI recommendation system.A spatiotemporal-context-based recurrent neural network and temporal-context-based long short-term memory network are used to model the users’recent and historical checkin trajectory sequences,respectively.Extensive experiments on the Foursquare and Gowalla datasets reveal that the proposed method outperforms several other baseline methods in terms of three evaluation metrics.More specifically,LSTP-ASR outperforms the previously best baseline method(RTPM)with a 17.15%and 20.62%average improvement on the Foursquare and Gowalla datasets in terms of the Fβmetric,respectively. 展开更多
关键词 Location-based social networks adaptive successive point-of-interest recommendation long short-term preference trajectory sequences
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A Multilayer Network Constructed for Herb and Prescription Efficacy Analysis
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作者 Xindi Huang Liwei Liang +3 位作者 Sakirin Tam Hao Liang Xiong Cai Changsong Ding 《Computer Systems Science & Engineering》 2024年第3期691-704,共14页
Chinese Medicine(CM)has been widely used as an important avenue for disease prevention and treatment in China especially in the form of CM prescriptions combining sets of herbs to address patients’symptoms and syndro... Chinese Medicine(CM)has been widely used as an important avenue for disease prevention and treatment in China especially in the form of CM prescriptions combining sets of herbs to address patients’symptoms and syndromes.However,the selection and compatibility of herbs are complex and abstract due to intrinsic relationships between herbal properties and their overall functions.Network analysis is applied to demonstrate the complex relationships between individual herbal efficacy and the overall function of CM prescriptions.To illustrate their connections and correlations,prescription function(PF),prescription herb(PH),and herbal efficacy(HE)intranetworks are proposed based on CM theory to identify relationships between herbs and prescriptions.These three networks are then connected by PF-PH and PH-HE interlayer networks adopting herb dosage to form a multidimensional heterogeneous network,a Prescription-Herb-Function Network(PHFN).The network is applied to 112 classic prescriptions from Treatise on Exogenous Febrile and Miscellaneous Diseases to illustrate the application of PHFN.The PHFN is constructed including 146 functions in PF intra network,89 herbs in the PH intra network,and 163 herbal efficacies in the HE intra network.The results show that herb pairs with synergistic actions have stronger relevance,such as licorice-cassia twig,licorice-Chinese date,fresh ginger-Chinese date,etc.The integration of dosage to the network helps to indicate the main herbs for cluster analysis and automatic formulation.PHFN also reveals the internal relationships between the functions of prescriptions and composed herbal efficacies. 展开更多
关键词 Chinese medicine HERB FORMULA network analysis herb dosage
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A Fast Tongue Detection and Location Algorithm in Natural Environment 被引量:3
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作者 Lei Zhu Guojiang Xin +3 位作者 Xin Wang Changsong Ding Hao Liang Qilei Chen 《Computers, Materials & Continua》 SCIE EI 2022年第12期4727-4742,共16页
The collection and extraction of tongue images has always been an important part of intelligent tongue diagnosis.At present,the collection of tongue images generally needs to be completed in a sealed,stable light envi... The collection and extraction of tongue images has always been an important part of intelligent tongue diagnosis.At present,the collection of tongue images generally needs to be completed in a sealed,stable light environment,which is not conducive to the promotion of extensive tongue image and intelligent tongue diagnosis.In response to the problem,a newalgorithm named GCYTD(GELU-CA-YOLO Tongue Detection)is proposed to quickly detect and locate the tongue in a natural environment,which can greatly reduce the restriction of the tongue image collection environment.The algorithm is based on the YOLO(You Only Look Once)V4-tiny network model to detect the tongue.Firstly,the GELU(Gaussian Error Liner Units)activation function is integrated into the model to improve the training speed and reduce the number of model parameters;then,the CA(Coordinate Attention)mechanism is integrated into the model to enhance the detection precision and improve the failure tolerance of the model.Compared with the other classical algorithms,Experimental results show thatGCYTD algorithm has a better performance on the tongue images of all types in terms of training speed,tongue detection speed and detection precision,etc.The lighter model can contribute on deploying the tongue detection model on small mobile terminals. 展开更多
关键词 Tongue detection YOLO V4-tiny CA mechanism GELU
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Introduction to social sensing and big data computing for disaster management 被引量:1
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作者 Zhenlong Li Qunying Huang Christopher T.Emrich 《International Journal of Digital Earth》 SCIE EI 2019年第11期1198-1204,共7页
Traditional data collection methods such as remote sensing and field surveying often fail to offer timely information during or immediately following disaster events.Social sensing enables all citizens to become part ... Traditional data collection methods such as remote sensing and field surveying often fail to offer timely information during or immediately following disaster events.Social sensing enables all citizens to become part of a large sensor network,which is low cost,more comprehensive,and always broadcasting situational awareness information.However,data collected with social sensing is often massive,heterogeneous,noisy,unreliable from some aspects,comes in continuous streams,and often lacks geospatial reference information.Together,these issues represent a grand challenge toward fully leveraging social sensing for emergency management decision making under extreme duress.Meanwhile,big data computing methods and technologies such as high-performance computing,deep learning,and multi-source data fusion become critical components of using social sensing to understand the impact of and response to the disaster events in a timely fashion.This special issue captures recent advancements in leveraging social sensing and big data computing for supporting disaster management.Specifically analyzed within these papers are some of the promises and pitfalls of social sensing data for disaster relevant information extraction,impact area assessment,population mapping,occurrence patterns,geographical disparities in social media use,and inclusion in larger decision support systems. 展开更多
关键词 Social media VGI big data natural hazards spatial computing
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A GIS-based analytical framework for evaluating the effect of COVID-19 on the restaurant industry with big data 被引量:1
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作者 Siqin Wang Ruomei Wang +2 位作者 Xiao Huang Zhenlong Li Shuming Bao 《Big Earth Data》 EI CSCD 2023年第1期37-58,共22页
COVID-19 cripples the restaurant industry as a crucial socioeconomic sector that contributes immensely to the global economy.However,what the current literature less explored is to quantify the effect of COVID-19 on r... COVID-19 cripples the restaurant industry as a crucial socioeconomic sector that contributes immensely to the global economy.However,what the current literature less explored is to quantify the effect of COVID-19 on restaurant visitation and revenue at different spatial scales,as well as its relationship with the neighborhood character-istics of customers’origins.Based on the Point of Interest(POI)measures derived from SafeGraph data providing mobility records of 45 million cell phone users in the US,our study takes Lower Manhattan,New York City,as the pilot study,and aims to examine 1)the change of restaurant visitations and revenue in the period prior to and after the COVID-19 outbreak,2)the areas where restaurant customers live,and 3)the association between the neighborhood characteristics of these areas and lost customers.By doing so,we provide a geographic information system-based analytical frame-work integrating the big data mining,web crawling techniques,and spatial-economic modelling.Our analytical framework can be implemented to estimate the broader effect of COVID-19 on other industries and can be augmented in a financially monitoring manner in response to future pandemics or public emergencies. 展开更多
关键词 COVID-19 pandemic effect restaurant visitation human mobility New York City
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Correlation-Aware Replica Prefetching Strategy to Decrease Access Latency in Edge Cloud
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作者 Yang Liang Zhigang Hu +1 位作者 Xinyu Zhang Hui Xiao 《China Communications》 SCIE CSCD 2021年第9期249-264,共16页
With the number of connected devices increasing rapidly,the access latency issue increases drastically in the edge cloud environment.Massive low time-constrained and data-intensive mobile applications require efficien... With the number of connected devices increasing rapidly,the access latency issue increases drastically in the edge cloud environment.Massive low time-constrained and data-intensive mobile applications require efficient replication strategies to decrease retrieval time.However,the determination of replicas is not reasonable in many previous works,which incurs high response delay.To this end,a correlation-aware replica prefetching(CRP)strategy based on the file correlation principle is proposed,which can prefetch the files with high access probability.The key is to determine and obtain the implicit high-value files effectively,which has a significant impact on the performance of CRP.To achieve the goal of accelerating the acquisition of implicit highvalue files,an access rule management method based on consistent hashing is proposed,and then the storage and query mechanisms for access rules based on adjacency list storage structure are further presented.The theoretical analysis and simulation results corroborate that CRP shortens average response time over 4.8%,improves average hit ratio over 4.2%,reduces transmitting data amount over 8.3%,and maintains replication frequency at a reasonable level when compared to other schemes. 展开更多
关键词 edge cloud access latency replica prefetching correlation-aware access rule
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Sequence-Based Predicting Bacterial Essential ncRNAs Algorithm by Machine Learning
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作者 Yuan-Nong Ye Ding-Fa Liang +1 位作者 Abraham Alemayehu Labena Zhu Zeng 《Intelligent Automation & Soft Computing》 SCIE 2023年第6期2731-2741,共11页
Essential ncRNA is a type of ncRNAwhich is indispensable for the sur-vival of organisms.Although essential ncRNAs cannot encode proteins,they are as important as essential coding genes in biology.They have got wide va... Essential ncRNA is a type of ncRNAwhich is indispensable for the sur-vival of organisms.Although essential ncRNAs cannot encode proteins,they are as important as essential coding genes in biology.They have got wide variety of applications such as antimicrobial target discovery,minimal genome construction and evolution analysis.At present,the number of species required for the deter-mination of essential ncRNAs in the whole genome scale is still very few due to the traditional methods are time-consuming,laborious and costly.In addition,tra-ditional experimental methods are limited by the organisms as less than 1%of bacteria can be cultured in the laboratory.Therefore,it is important and necessary to develop theories and methods for the recognition of essential non-coding RNA.In this paper,we present a novel method for predicting essential ncRNA by using both compositional and derivative features calculated by information theory of ncRNA sequences.The method was developed with Support Vector Machine(SVM).The accuracy of the method was evaluated through cross-species cross-vali-dation and found to be between 0.69 and 0.81.It shows that the features we selected have good performance for the prediction of essential ncRNA using SVM.Thus,the method can be applied for discovering essential ncRNAs in bacteria. 展开更多
关键词 BIOINFORMATICS biological information theory biomedical informatics
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Crowdsourcing Geospatial Data for Earth and Human Observations:A Review
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作者 Xiao Huang Siqin Wang +15 位作者 Di Yang Tao Hu Meixu Chen Mengxi Zhang Guiming Zhang Filip Biljecki Tianjun Lu Lei Zou Connor Y.H.Wu Yoo Min Park Xiao Li Yunzhe Liu Hongchao Fan Jessica Mitchell Zhenlong Li Alexer Hohl 《Journal of Remote Sensing》 2024年第1期766-790,共25页
The transformation from authoritative to user-generated data landscapes has garnered considerable attention,notably with the proliferation of crowdsourced geospatial data.Facilitated by advancements in digital technol... The transformation from authoritative to user-generated data landscapes has garnered considerable attention,notably with the proliferation of crowdsourced geospatial data.Facilitated by advancements in digital technology and high-speed communication,this paradigm shift has democratized data collection,obliterating traditional barriers between data producers and users.While previous literature has compartmentalized this subject into distinct platforms and application domains,this review offers a holistic examination of crowdsourced geospatial data.Employing a narrative review approach due to the interdisciplinary nature of the topic,we investigate both human and Earth observations through crowdsourced initiatives.This review categorizes the diverse applications of these data and rigorously examines specific platforms and paradigms pertinent to data collection.Furthermore,it addresses salient challenges,encompassing data quality,inherent biases,and ethical dimensions.We contend that this thorough analysis will serve as an invaluable scholarly resource,encapsulating the current state-of-the-art in crowdsourced geospatial data,and offering strategic directions for future interdisciplinary research and applications across various sectors. 展开更多
关键词 crowdsourced geospatial datafacilitated crowdsourcing human observations geospatial data high speed communication paradigm shift earth observations digital technology
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A novel random forest-based approach for the non-destructive and explainable estimation of ammonia and chlorophyll in fresh-cut rocket leaves
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作者 Stefano Polimena Gianvito Pio +3 位作者 Maria Cefola Michela Palumbo Michelangelo Ceci Giovanni Attolico 《Information Processing in Agriculture》 2025年第2期221-231,共11页
The perceived visual quality of fruits and vegetables plays a central role in the choices made by retail customers.Machine learning(ML)approaches based on image analysis have been recently proposed to overcome the poo... The perceived visual quality of fruits and vegetables plays a central role in the choices made by retail customers.Machine learning(ML)approaches based on image analysis have been recently proposed to overcome the poor efficiency and subjectivity of human visual evaluation as well as the expensiveness and destructiveness of physical and chemical methods that measure internal indicators.In this paper,we propose a ML method based on Random Forests for estimating the chlorophyll and ammonia contents(considered,in the literature,reliable indicators of product freshness)from images of fresh-cut rocket leaves.Our approach copes with specific issues raised by(i)the non-uniform distributions of ammonia and chlorophyll values and(ii)the need to provide insights into the features that produce a particular model outcome,aiming to enhance its trustworthiness.Our experiments,performed on real images of fresh-cut rocket leaves,proved that the proposed approach significantly outperforms 7 competitor methods,obtaining an improvement of the RSE results of 6.6%for the prediction of the ammonia and of 10.4%for the prediction of the chlorophyll over its best competitor.Moreover,a specific analysis of the explainability of the predictions showed that the learned models are based on reasonable features,empowering their acceptance in real-world applications. 展开更多
关键词 Fresh-cut rocket leaves Consumer acceptability Machine learning Explainability
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Ultrasound and gene-guided microwave ablation vs.surgery for low-risk papillary thyroid carcinoma:a prospective observational cohort study
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作者 Yunfang Yu Yuxin Shen +6 位作者 Yujie Tan Yisikandaer Yalikun Tian Tian Qingqing Tang Qiyun Ou Yue Zhu Miaoyun Long 《Precision Clinical Medicine》 2025年第2期124-134,共11页
Objective:This prospective observational cohort real-world study evaluates and compares the efficacy and prognosis of ultrasound(US)and gene-based microwave ablation(MWA)and surgical treatment in patients with low-ris... Objective:This prospective observational cohort real-world study evaluates and compares the efficacy and prognosis of ultrasound(US)and gene-based microwave ablation(MWA)and surgical treatment in patients with low-risk papillary thyroid carcinoma(PTC),emphasizing the influence of genetic mutations on low-risk patient selection.Background:MWA,a minimally invasive technique,is increasingly recognized in the management of PTC.While traditional criteria for ablation focus on tumor size,number,and location,the impact of genetic mutations on treatment efficacy remains underexplored.Methods:A total of 201 patients with low-risk PTC without metastasis were prospectively enrolled.All patients underwent US and next-generation sequencing to confirm low-risk status.Patients chose either ablation or surgery and were monitored until November 2024.Efficacy and complications were assessed using thyroid US and contrast-enhanced US.Results:The median follow-up of this study is 12 months.There is no significant difference between the ablation group(3.0%)and the surgery group(1.0%)in disease free survival(P=0.360).However,the surgery group exhibited a significantly higher complication rate,particularly for temporary hypoparathyroidism(P<0.001).Ablation offers notable advantages,including shorter treatment duration,faster recovery,less intraoperative blood loss,and reduced costs(P<0.001),while maintaining favorable safety and comparable efficiency.Conclusions:For patients with low-risk genetic mutations,ablation provides comparable efficacy and disease free survival to surgery,with significant benefits in safety,recovery,and overall cost.Guided by US and next-generation sequencing,precise patient selection enhances the potential of ablation as a promising,minimally invasive alternative to surgery in the management of low-risk PTC. 展开更多
关键词 papillary thyroid carcinoma next-generation sequencing microwave ablation surgical treatment
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Using geospatial social media data for infectious disease studies: a systematic review 被引量:1
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作者 Fengrui Jing Zhenlong Li +3 位作者 Shan Qiao Jiajia Zhang Banky Olatosi Xiaoming Li 《International Journal of Digital Earth》 SCIE EI 2023年第1期130-157,共28页
Geospatial social media(GSM)data has been increasingly used in public health due to its rich,timely,and accessible spatial information,particularly in infectious disease research.This review synthesized 86 research ar... Geospatial social media(GSM)data has been increasingly used in public health due to its rich,timely,and accessible spatial information,particularly in infectious disease research.This review synthesized 86 research articles that use GSM data in infectious diseases published between December 2013 and March 2022.These articles cover 12 infectious disease types ranging from respiratory infectious diseases to sexually transmitted diseases with spatial levels varying from the neighborhood,county,state,and country.We categorized these studies into three major infectious disease research domains:surveillance,explanation,and prediction.With the assistance of advanced computing,statistical and spatial methods,GSM data has been widely and deeply applied to these domains,particularly in surveillance and explanation domains.We further identified four knowledge gaps in terms of contextual information use,application scopes,spatiotemporal dimension,and data limitations and proposed innovation opportunities for future research.Ourfindings will contribute to a better understanding of using GSM data in infectious diseases studies and provide insights into strategies for using GSM data more effectively in future research. 展开更多
关键词 Public health social media infectious diseases GEOGRAPHY spatial analysis
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Human mobility data in the COVID-19 pandemic:characteristics,applications,and challenges 被引量:8
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作者 Tao Hu Siqin Wang +12 位作者 Bing She Mengxi Zhang Xiao Huang Yunhe Cui Jacob Khuri Yaxin Hu Xiaokang Fu Xiaoyue Wang Peixiao Wang Xinyan Zhu Shuming Bao Wendy Guan Zhenlong Li 《International Journal of Digital Earth》 SCIE 2021年第9期1126-1147,共22页
The COVID-19 pandemic poses unprecedented challenges around the world.Many studies have applied mobility data to explore spatiotemporal trends over time,investigate associations with other variables,and predict or sim... The COVID-19 pandemic poses unprecedented challenges around the world.Many studies have applied mobility data to explore spatiotemporal trends over time,investigate associations with other variables,and predict or simulate the spread of COVID-19.Our objective was to provide a comprehensive overview of human mobility open data to guide researchers and policymakers in conducting data-driven evaluations and decision-making for the COVID-19 pandemic and other infectious disease outbreaks.We summarized the mobility data usage in COVID-19 studies by reviewing recent publications on COVID-19 and human mobility from a data-oriented perspective.We identified three major sources of mobility data:public transit systems,mobile operators,and mobile phone applications.Four approaches have been commonly used to estimate human mobility:public transit-based flow,social activity patterns,index-based mobility data,and social media-derived mobility data.We compared mobility datasets’characteristics by assessing data privacy,quality,space–time coverage,high-performance data storage and processing,and accessibility.We also present challenges and future directions of using mobility data.This review makes a pivotal contribution to understanding the use of and access to human mobility data in the COVID-19 pandemic and future disease outbreaks. 展开更多
关键词 COVID-19 public health human mobility open data mobile phone mobility index
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Potential mechanism of acupuncture on overeating and the significance in preventing and treating adiposity-based chronic disease:A new perspective based on the addiction model
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作者 Pei-ming ZHANG Dan-chun LAN +5 位作者 Ting-ting GU Jia-hua WU Rui-rui TAO Chun-zhi TANG Zi-yong LI Li-ming LU 《World Journal of Acupuncture-Moxibustion》 2025年第4期312-319,共8页
Overeating is a risk factor and a management challenge in adiposity-based chronic disease(ABCD).Acupuncture has shown high safety and reliable clinical evidence in addressing overeating,and it is the promising potenti... Overeating is a risk factor and a management challenge in adiposity-based chronic disease(ABCD).Acupuncture has shown high safety and reliable clinical evidence in addressing overeating,and it is the promising potential non-pharmacological intervention.However,the mechanism underlying its effects has not been sufficiently summarized.The addiction model offers a framework to elucidate the mechanism of this aberrant eating behavior and provides novel perspectives and breakthrough points for optimizing clinical acupuncture strategies in ABCD management.In the paper,through analyzing domestic and in-ternational relevant findings,the characteristics of overeating based on food addiction,the relationship between overeating and ABCD,and the potential effect mechanisms of acupuncture for FA have been re-viewed and summarized.Including adaptive balance of transmitters and hormones,functional networks,periphery-central connection,and cross-system interaction.In future studies,the maturely-developed ad-diction research methods should be adopted to deepen the exploration on the mechanism of acupuncture effect,addiction medicine should be leveraged to shatter the cognitive barriers surrounding acupuncture’s role in mind-body regulation for ABCD treatment,and the prevention and treatment of overeating via acupuncture should be organically integrated into multidisciplinary management strategies. 展开更多
关键词 Acupuncture Adiposity Overeating Addiction Mechanism
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Inductive Relation Prediction by Disentangled Subgraph Structure
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作者 Guiduo Duan Rui Guo +2 位作者 Wenlong Luo Guangchun Luo Tianxi Huang 《Tsinghua Science and Technology》 SCIE EI CAS CSCD 2024年第5期1566-1579,共14页
Currently,most existing inductive relation prediction approaches are based on subgraph structures,with subgraph features extracted using graph neural networks to predict relations.However,subgraphs may contain disconn... Currently,most existing inductive relation prediction approaches are based on subgraph structures,with subgraph features extracted using graph neural networks to predict relations.However,subgraphs may contain disconnected regions,which usually represent different semantic ranges.Because not all semantic information about the regions is helpful in relation prediction,we propose a relation prediction model based on a disentangled subgraph structure and implement a feature updating approach based on relevant semantic aggregation.To indirectly achieve the disentangled subgraph structure from a semantic perspective,the mapping of entity features into different semantic spaces and the aggregation of related semantics on each semantic space are updated.The disentangled model can focus on features having higher semantic relevance in the prediction,thus addressing a problem with existing approaches,which ignore the semantic differences in different subgraph structures.Furthermore,using a gated recurrent neural network,this model enhances the features of entities by sorting them by distance and extracting the path information in the subgraphs.Experimentally,it is shown that when there are numerous disconnected regions in the subgraph,our model outperforms existing mainstream models in terms of both Area Under the Curve-Precision-Recall(AUC-PR)and Hits@10.Experiments prove that semantic differences in the knowledge graph can be effectively distinguished and verify the effectiveness of this method. 展开更多
关键词 disentangled subgraph structure knowledge graph completion Gated Recurrent Unit(GRU) feature updating
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