This study aimed to examine verbal and visual-spatial working memory(WM)dysfunction in patients with schizophrenia.We compared 60 patients with schizophrenia with 57 healthy controls(matched for age,educational level,...This study aimed to examine verbal and visual-spatial working memory(WM)dysfunction in patients with schizophrenia.We compared 60 patients with schizophrenia with 57 healthy controls(matched for age,educational level,and IQ)on three WM tasks.Patients with schizophrenia performed significantly more poorly than healthy controls on verbal,visual,and spatial WM tests.Moreover,WM deficits were inversely associated with both the positive and negative symptoms of the patients.Taken together,these findings suggest that there are pervasive WM impairments in patients with schizophrenia.In addition,clinical features may play a significant role in the expression of WM deficits.展开更多
基金supported partially by the National Science Fund China(81088001,91132701)a grant from the Knowledge Innovation Project of the Chinese Academy of Sciences(KSCX2-EW-J-8)+1 种基金the CAS/SAFEA International Partnership Program for Creative Research Teams(Y2CX131003)the Key Laboratory of Mental Health,Institute of Psychology.
文摘This study aimed to examine verbal and visual-spatial working memory(WM)dysfunction in patients with schizophrenia.We compared 60 patients with schizophrenia with 57 healthy controls(matched for age,educational level,and IQ)on three WM tasks.Patients with schizophrenia performed significantly more poorly than healthy controls on verbal,visual,and spatial WM tests.Moreover,WM deficits were inversely associated with both the positive and negative symptoms of the patients.Taken together,these findings suggest that there are pervasive WM impairments in patients with schizophrenia.In addition,clinical features may play a significant role in the expression of WM deficits.
