Immune and inflammatory responses have been known to play an important role in the initiation, progression and destabilization of atherosclerosis. Chronic inflammatory diseases such as rheumatoid arthritis and probabl...Immune and inflammatory responses have been known to play an important role in the initiation, progression and destabilization of atherosclerosis. Chronic inflammatory diseases such as rheumatoid arthritis and probably inflammatory bowel diseases such as Crohn's disease which are associated with systemic inflammation also appear to increase the likelihood of clinically manifest atherosclerotic vascular disease. Acute myocardial infarction (AMI) triggers an intense acute inflammatory response both locally and systemically. However, the differences in systemic immune and inflammatory response between AMI and chronic phase of atherosclerosis are not fully understood.展开更多
文摘Immune and inflammatory responses have been known to play an important role in the initiation, progression and destabilization of atherosclerosis. Chronic inflammatory diseases such as rheumatoid arthritis and probably inflammatory bowel diseases such as Crohn's disease which are associated with systemic inflammation also appear to increase the likelihood of clinically manifest atherosclerotic vascular disease. Acute myocardial infarction (AMI) triggers an intense acute inflammatory response both locally and systemically. However, the differences in systemic immune and inflammatory response between AMI and chronic phase of atherosclerosis are not fully understood.