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Fault injection system for automatic testing system 被引量:1
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作者 王胜文 洪炳熔 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2003年第3期321-324,共4页
Considering the deficiency of the means for confirming the attribution of fault redundancy in the re-search of Automatic Testing System(ATS) , a fault-injection system has been proposed to study fault redundancyof aut... Considering the deficiency of the means for confirming the attribution of fault redundancy in the re-search of Automatic Testing System(ATS) , a fault-injection system has been proposed to study fault redundancyof automatic testing system through compurison. By means of a fault-imbeded environmental simulation, thefaults injected at the input level of the software are under test. These faults may induce inherent failure mode,thus bringing about unexpected output, and the anticipated goal of the test is attained. The fault injection con-sists of voltage signal generator, current signal generator and rear drive circuit which are specially developed,and the ATS can work regularly by means of software simulation. The experimental results indicate that the faultinjection system can find the deficiency of the automatic testing software, and identify the preference of fault re-dundancy. On the other hand, some soft deficiency never exposed before can be identified by analyzing the tes-ting results. 展开更多
关键词 Fault injection comparing method rear drive ATS
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Automatic Stabilization of an Adaptive Feedback Control for Noise Cancelling In-ear Headphones
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作者 Sven Hoeber Christian Pape Eduard Reithmeier 《Journal of Mechanics Engineering and Automation》 2016年第7期364-372,共9页
Headphones with an integrated active noise cancellation system have been increasingly introduced to the consumer market in recent years. When exposing the human ear to active noise sources in this striking distance, t... Headphones with an integrated active noise cancellation system have been increasingly introduced to the consumer market in recent years. When exposing the human ear to active noise sources in this striking distance, the ensuring of a safe sound pressure level is vital. In feedback systems, this is coupled with the stability of the closed control loop; stable controller design is thus essential. However, changes in the control path during run-time can cause the stable control system to become unstable, resulting in an overdrive of the speakers in the headphones. This paper proposes a method, which enables the real-time analysis of the current system state and if necessary stabilizes the closed loop while maintaining the active noise reduction. This is achieved by estimating and evaluating the open loop behavior with an adaptive filter and subsequently limiting the controller gain in respect to the stability margin. 展开更多
关键词 Active noise cancellation feedback control stability analysis.
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A note on diagnosis and performance degradation detection in automatic control systems towards functional safety and cyber security 被引量:5
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作者 Steven X.Ding 《Security and Safety》 2022年第1期2-30,共29页
This note addresses diagnosis and performance degradation detection issues from an integrated viewpoint of functionality maintenance and cyber security of automatic control systems.It calls for more research attention... This note addresses diagnosis and performance degradation detection issues from an integrated viewpoint of functionality maintenance and cyber security of automatic control systems.It calls for more research attention on three aspects:(i)application of control and detection uni ed framework to enhancing the diagnosis capability of feedback control systems,(ii)projection-based fault detection,and complementary and explainable applications of projection-and machine learning-based techniques,and(iii)system performance degradation detection that is of elemental importance for today's automatic control systems.Some ideas and conceptual schemes are presented and illustrated by means of examples,serving as convincing arguments for research e orts in these aspects.They would contribute to the future development of capable diagnosis systems for functionality safe and cyber secure automatic control systems. 展开更多
关键词 Diagnosis in automatic control systems Cyber security in industrial cyber physical systems Uni ed framework of control and detection Projection-based diagnosis Explainable application of ML-methods Performance degradation detection
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Multi-Step Clustering of Smart Meters Time Series:Application to Demand Flexibility Characterization of SME Customers
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作者 Santiago Bañales Raquel Dormido Natividad Duro 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期869-907,共39页
Customer segmentation according to load-shape profiles using smart meter data is an increasingly important application to vital the planning and operation of energy systems and to enable citizens’participation in the... Customer segmentation according to load-shape profiles using smart meter data is an increasingly important application to vital the planning and operation of energy systems and to enable citizens’participation in the energy transition.This study proposes an innovative multi-step clustering procedure to segment customers based on load-shape patterns at the daily and intra-daily time horizons.Smart meter data is split between daily and hourly normalized time series to assess monthly,weekly,daily,and hourly seasonality patterns separately.The dimensionality reduction implicit in the splitting allows a direct approach to clustering raw daily energy time series data.The intraday clustering procedure sequentially identifies representative hourly day-unit profiles for each customer and the entire population.For the first time,a step function approach is applied to reduce time series dimensionality.Customer attributes embedded in surveys are employed to build external clustering validation metrics using Cramer’s V correlation factors and to identify statistically significant determinants of load-shape in energy usage.In addition,a time series features engineering approach is used to extract 16 relevant demand flexibility indicators that characterize customers and corresponding clusters along four different axes:available Energy(E),Temporal patterns(T),Consistency(C),and Variability(V).The methodology is implemented on a real-world electricity consumption dataset of 325 Small and Medium-sized Enterprise(SME)customers,identifying 4 daily and 6 hourly easy-to-interpret,well-defined clusters.The application of the methodology includes selecting key parameters via grid search and a thorough comparison of clustering distances and methods to ensure the robustness of the results.Further research can test the scalability of the methodology to larger datasets from various customer segments(households and large commercial)and locations with different weather and socioeconomic conditions. 展开更多
关键词 Electric load clustering load profiling smart meters machine learning data mining demand flexibility demand response
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Fluid-based moderate collision avoidance for UAV formation in 3-D low-altitude environments 被引量:1
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作者 Menghua ZHANG Honglun WANG +5 位作者 Zhiyu LI Yanxiang WANG Xianglun ZHANG Qiang TANG Shichao MA Jianfa WU 《Chinese Journal of Aeronautics》 2025年第6期533-551,共19页
Aiming to address the Unmanned Aerial Vehicle(UAV) formation collision avoidance problem in Three-Dimensional(3-D) low-altitude environments where dense various obstacles exist, a fluid-based path planning framework n... Aiming to address the Unmanned Aerial Vehicle(UAV) formation collision avoidance problem in Three-Dimensional(3-D) low-altitude environments where dense various obstacles exist, a fluid-based path planning framework named the Formation Interfered Fluid Dynamical System(FIFDS) with Moderate Evasive Maneuver Strategy(MEMS) is proposed in this study.First, the UAV formation collision avoidance problem including quantifiable performance indexes is formulated. Second, inspired by the phenomenon of fluids continuously flowing while bypassing objects, the FIFDS for multiple UAVs is presented, which contains a Parallel Streamline Tracking(PST) method for formation keeping and the traditional IFDS for collision avoidance. Third, to rationally balance flight safety and collision avoidance cost, MEMS is proposed to generate moderate evasive maneuvers that match up with collision risks. Comprehensively containing the time and distance safety information, the 3-D dynamic collision regions are modeled for collision prediction. Then, the moderate evasive maneuver principle is refined, which provides criterions of the maneuver amplitude and direction. On this basis, an analytical parameter mapping mechanism is designed to online optimize IFDS parameters. Finally, the performance of the proposed method is validated by comparative simulation results and real flight experiments using fixed-wing UAVs. 展开更多
关键词 Unmanned aerial vehicle Formation collision avoidance:3-D low-altitude environments Interfered fluid dynamical system 3-D dynamic collision region
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Galloping characteristics of catenary positive feeder considering aerodynamic damping
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作者 LI Yanzhe JIN Xianglong +3 位作者 ZHAO Shanpeng ZHANG Youpeng WANG Sihua LI Wanrun 《Journal of Measurement Science and Instrumentation》 2025年第1期142-153,共12页
The purpose of this study is to analyze the galloping characteristics of the catenary positive feeder in fluctuating wind areas considering dynamic-wind angle of attack and aerodynamic damping.Firstly,the flow field m... The purpose of this study is to analyze the galloping characteristics of the catenary positive feeder in fluctuating wind areas considering dynamic-wind angle of attack and aerodynamic damping.Firstly,the flow field model of the catenary positive feeder was established,the fluctuating wind field was simulated by Davenport wind power spectrum and linear filtering method,and the wind speed at inlet in calculation domain was controlled by editing the profile file to simulate and calculate the aerodynamic characteristics of the positive feeder in the fluctuating wind area.Then,taking the positive feeder as the research object,the mathematical model of actual structure and the corresponding finite element model were established.By applying the wind load to the finite element model,the influence of aerodynamic damping caused by the self-movement of the positive feeder on the galloping response was analyzed,and the frequency domain characteristics of galloping displacement of the positive feeder considering aerodynamic damping were studied.Finally,the calculation method of aerodynamic damping by the Guidelines for Electrical Transmission Line Structural Loading(ASCE No.74)was used for the galloping response of the positive feeder and compared with the proposed method.The results show that when considering aerodynamic damping,the galloping amplitude of the positive feeder decreases significantly,and the first-order resonance effect on the vertical displacement and horizontal displacement decreases significantly.The galloping trajectories calculated by the two methods are consistent.Therefore,this study is of great significance to further clarify the ice-free galloping mechanism of the catenary positive feeder in violent wind areas. 展开更多
关键词 positive feeder aerodynamic damping fluctuating wind area galloping characteristics nonlinear dynamic analysis
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Intelligent sitting postural anomaly detection system for wheelchair users with unsupervised techniques
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作者 Patrick Vermander Aitziber Mancisidor +2 位作者 Raffaele Gravina Itziar Cabanes Giancarlo Fortino 《Digital Communications and Networks》 2025年第3期622-633,共12页
Detecting sitting posture abnormalities in wheelchair users enables early identification of changes in their functional status.To date,this detection has relied on in-person observation by medical specialists.However,... Detecting sitting posture abnormalities in wheelchair users enables early identification of changes in their functional status.To date,this detection has relied on in-person observation by medical specialists.However,given the challenges faced by health specialists to carry out continuous monitoring,the development of an intelligent anomaly detection system is proposed.Unlike other authors,where they use supervised techniques,this work proposes using unsupervised techniques due to the advantages they offer.These advantages include the lack of prior labeling of data,and the detection of anomalies previously not contemplated,among others.In the present work,an individualized methodology consisting of two phases is developed:characterizing the normal sitting pattern and determining abnormal samples.An analysis has been carried out between different unsupervised techniques to study which ones are more suitable for postural diagnosis.It can be concluded,among other aspects,that the utilization of dimensionality reduction techniques leads to improved results.Moreover,the normality characterization phase is deemed necessary for enhancing the system’s learning capabilities.Additionally,employing an individualized approach to the model aids in capturing the particularities of the various pathologies present among subjects. 展开更多
关键词 Sitting posture monitoring Anomaly detection Assistive technology Pressure sensors Unsupervised techniques INDIVIDUALIZATION WHEELCHAIR
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A lifting-wavelet-based iterative thresholding correction for atomic force microscopy images with vertical distortion
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作者 Yifan Bai Yinan Wu Yongchun Fang 《Nanotechnology and Precision Engineering》 2025年第3期29-40,共12页
To eliminate distortion caused by vertical drift and illusory slopes in atomic force microscopy(AFM)imaging,a lifting-wavelet-based iterative thresholding correction method is proposed in this paper.This method achiev... To eliminate distortion caused by vertical drift and illusory slopes in atomic force microscopy(AFM)imaging,a lifting-wavelet-based iterative thresholding correction method is proposed in this paper.This method achieves high-quality AFM imaging via line-by-line corrections for each distorted profile along the fast axis.The key to this line-by-line correction is to accurately simulate the profile distortion of each scanning row.Therefore,a data preprocessing approach is first developed to roughly filter out most of the height data that impairs the accuracy of distortion modeling.This process is implemented through an internal double-screening mechanism.A line-fitting method is adopted to preliminarily screen out the obvious specimens.Lifting wavelet analysis is then carried out to identify the base parts that are mistakenly filtered out as specimens so as to preserve most of the base profiles and provide a good basis for further distortion modeling.Next,an iterative thresholding algorithm is developed to precisely simulate the profile distortion.By utilizing the roughly screened base profile,the optimal threshold,which is used to screen out the pure bases suitable for distortion modeling,is determined through iteration with a specified error rule.On this basis,the profile distortion is accurately modeled through line fitting on the finely screened base data,and the correction is implemented by subtracting the modeling result from the distorted profile.Finally,the effectiveness of the proposed method is verified through experiments and applications. 展开更多
关键词 Atomic force microscopy Lifting wavelet analysis Iterative thresholding algorithm Vertical distortion
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Dismantling of Civil Aircraft:Prospects and Future of Sustainable Aviation
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作者 MA Congyao WANG Jianyuan 《International Journal of Plant Engineering and Management》 2025年第1期17-27,共11页
With the development of civil aviation industry,the number of retired aircraft is increasing year by year.How to deal with retired aircraft,build aviation,avoid damage to the ecological environment,and develop their r... With the development of civil aviation industry,the number of retired aircraft is increasing year by year.How to deal with retired aircraft,build aviation,avoid damage to the ecological environment,and develop their residual value has attracted widespread attention internationally,and gradually formed dismantling industry for the commercial and reuse of retired aircraft.From the perspective of the industrial chain,the essence of aircraft dismantling is how to maximize the value of highvalue assets at the of their life cycle,that is,to balance the value of aircraft parts and the value of the whole aircraft,which is the last chain in the complete industrial of civil aircraft from design,manufacturing to usage and retirement.The paper studied the dismantling industrial modes of civil aircraft,analyzed the problems and challenges faced by aircraft dismantling,and put forward relevant measures and suggestions,which point out the direction for the development of domestic civil aircraft dismantling industry. 展开更多
关键词 sustainable aviation civil aircraft aircraft dismantling AIRWORTHINESS
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Sensing-noise reduction in active disturbance rejection controllers:a permanent magnet synchronous generator-based wind turbine example
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作者 Mario Andrés Aguilar-Orduña Brian Camilo Gómez-León +1 位作者 Hebertt Sira-Ramírez Rubén Alejandro Garrido-Moctezuma 《Control Theory and Technology》 2025年第3期378-396,共19页
Active disturbance rejection control(ADRC)exhibits notable resilience against both internal and external disturbances.Its straightforward implementation further enhances its appeal for controlling a diverse class of s... Active disturbance rejection control(ADRC)exhibits notable resilience against both internal and external disturbances.Its straightforward implementation further enhances its appeal for controlling a diverse class of systems.However,the high-gain nature of the extended state observer,which is the core of ADRC,may degrade performance when faced with high-frequency sensing noise—a common challenge in real-world settings.This article addresses this issue through a specifically placed and particularly designed low-pass filterwhile preserving the ease of implementation characteristic of ADRC.This article proposes a simple tuning method for the filter-controller structure to improve the scheme’s design process.Theoretical results simplify the design process based on the Routh–Hurwitz criterion such that the additional low-pass filter does not affect the closedloop stability.The maximum power point tracking task on a wind turbine—a nonlinear system requiring the measurement of inherently noisy signals,such as electrical currents—is addressed to illustrate the design process of the proposed approach.Real-time experiments on a laboratory platform emulating a Permanent Magnet Synchronous Generator-based wind turbine endorse the enhanced scheme’s effectiveness in mitigating high-frequency sensing noise. 展开更多
关键词 ADRC Noise reduction Wind turbine PMSG·MPPT
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DWDet:A Fine-Grained Object DetectionAlgorithm for Remote Sensing Aircraft
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作者 Meijing Gao Yonghao Yan +5 位作者 Xiangrui Fan Huanyu Sun Sibo Chen Xu Chen Bingzhou Sun Ning Guan 《Journal of Beijing Institute of Technology》 2025年第4期337-349,共13页
Fine-grained aircraft target detection in remote sensing holds significant research valueand practical applications,particularly in military defense and precision strikes.Given the complex-ity of remote sensing images... Fine-grained aircraft target detection in remote sensing holds significant research valueand practical applications,particularly in military defense and precision strikes.Given the complex-ity of remote sensing images,where targets are often small and similar within categories,detectingthese fine-grained targets is challenging.To address this,we constructed a fine-grained dataset ofremotely sensed airplanes;for the problems of remote sensing fine-grained targets with obvious head-to-tail distributions and large variations in target sizes,we proposed the DWDet fine-grained tar-get detection and recognition algorithm.First,for the problem of unbalanced category distribution,we adopt an adaptive sampling strategy.In addition,we construct a deformable convolutional blockand improve the decoupling head structure to improve the detection effect of the model ondeformed targets.Then,we design a localization loss function,which is used to improve the model’slocalization ability for targets of different scales.The experimental results show that our algorithmimproves the overall accuracy of the model by 4.1%compared to the baseline model,and improvesthe detection accuracy of small targets by 12.2%.The ablation and comparison experiments alsoprove the effectiveness of our algorithm. 展开更多
关键词 remote sensing fine-grained recognition aircraft remote-sensing datasets multi-scaletarget detection
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Gray relational analysis and SBOA-BP for predicting settlement intervals of high-speed railway subgrade
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作者 Quanpeng He Shaoyuan Li 《Railway Sciences》 2025年第2期199-212,共14页
Purpose–The deformation of the roadbed is easily influenced by the external environment to improve the accuracy of high-speed railway subgrade settlement prediction.Design/methodology/approach–A high-speed railway s... Purpose–The deformation of the roadbed is easily influenced by the external environment to improve the accuracy of high-speed railway subgrade settlement prediction.Design/methodology/approach–A high-speed railway subgrade settlement interval prediction method using the secretary bird optimization(SBOA)algorithm to optimize the BP neural network under the premise of gray relational analysis is proposed.Findings–Using the SBOA algorithm to optimize the BP neural network,the optimal weights and thresholds are obtained,and the best parameter prediction model is combined.The data were collected from the sensors deployed through the subgrade settlement monitoring system,and the gray relational analysis is used to verify that all four influencing factors had a great correlation to the subgrade settlement,and the collected data are verified using the model.Originality/value–The experimental results show that the SBOA-BP model has higher prediction accuracy than the BP model,and the SBOA-BP model has a wider range of prediction intervals for a given confidence level,which can provide higher guiding value for practical engineering applications. 展开更多
关键词 Gray relational analysis Secretary bird optimization algorithm Backpropagation neural network Subgrade settlement Interval prediction
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A Comprehensive Review on Bridging the Research Gap in AI-Driven Material Simulation for FRP Composites
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作者 Alin Dinita Cosmina-Mihaela Rosca +1 位作者 Maria Tanase Adrian Stancu 《Computer Modeling in Engineering & Sciences》 2025年第7期147-199,共53页
Fiber-reinforced polymer(FRP)composites are renowned for their high mechanical strength,durability,and lightweight properties,making them integral to civil engineering,aerospace,and automotive manufacturing.Traditiona... Fiber-reinforced polymer(FRP)composites are renowned for their high mechanical strength,durability,and lightweight properties,making them integral to civil engineering,aerospace,and automotive manufacturing.Traditionally,the simulation and optimization of FRP materials have relied on finite element(FE)methods,which,while effective,often fall short in capturing the intricate behaviors of these composites under diverse conditions.Concrete examples in this regard involve modeling interfacial cracks,delaminations,or environmental effects that involve nonlinear phenomena.These degradation mechanisms exceed the capacity of classical FE models,as they are not detailed to the required level of detail.This aspect increases the time and computational resources required,leading to a need for optimization regarding fiber reinforcement configurations or multiple scenario load analysis.Thus,FE methods are inefficient compared to AI-based approaches that generalize material behavior based on extensive datasets.The advent of artificial intelligence(AI)has introduced advanced tools capable of enhancing the analysis and design of FRP materials.This review examines the current landscape of AI applications in FRP composite simulations,highlighting existing research gaps.Through a comprehensive bibliometric analysis,the study underscores the limited number of investigations focused on leveraging AI for FRP optimization.Furthermore,it synthesizes findings related to AI-driven simulation techniques,the mechanical properties of FRP composites,and strategies for predicting and improving their durability.This review comprehensively explores the potential of AI to overcome these limitations by synthesizing over 170 scientific works published between 2015 and 2025.Key findings highlight that supervised learning methods—especially neural networks,support vector machines,and gradient boosting models—achieve prediction accuracies above 90%for mechanical properties and defect classification.However,bibliometric analysis reveals that there are limited studies that address AI-driven optimization or standardized datasets for FRP applications.This review identifies eight core classification domains and eight regression domains where AI excels,including defect detection,bond strength prediction,and fiber orientation optimization. 展开更多
关键词 Artificial intelligence fiber-reinforced polymers material simulation machine learning deep learning optimization mechanical properties DURABILITY
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Artificial intelligence in contrast enhanced ultrasound:A new era for liver lesion assessment
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作者 Adriana Ciocalteu Cristiana M Urhut +3 位作者 Costin Teodor Streba Adina Kamal Madalin Mamuleanu Larisa D Sandulescu 《World Journal of Gastroenterology》 2025年第42期58-68,共11页
Artificial intelligence(AI)-augmented contrast-enhanced ultrasonography(CEUS)is emerging as a powerful tool in liver imaging,particularly in enhancing the accuracy of Liver Imaging Reporting and Data System(known as L... Artificial intelligence(AI)-augmented contrast-enhanced ultrasonography(CEUS)is emerging as a powerful tool in liver imaging,particularly in enhancing the accuracy of Liver Imaging Reporting and Data System(known as LI-RADS)classi-fication.This review synthesized published data on the integration of machine learning and deep learning techniques into CEUS,revealing that AI algorithms can improve the detection and quantification of contrast enhancement patterns.Such improvements led to more consistent LI-RADS categorization,reduced interoperator variability,and enabled real-time analysis that streamlined work-flow.The enhanced sensitivity of AI tools facilitated better differentiation between benign and malignant lesions,ultimately optimizing patient management.These advances suggest that AI-augmented CEUS could transform liver imaging by providing rapid,reliable,and objective assessments.However,the review also highlighted the need for further large-scale,multicenter studies to fully validate these findings and ensure the safe integration of AI into routine clinical practice.INTRODUCTION International hepatology society guidelines have established contrast-enhanced computed tomography(CT)and contrast-enhanced magnetic resonance imaging(MRI)as the imaging modalities of choice for diagnosing hepatocellular carcinoma(HCC)lesions larger than 1 cm.MRI remains the gold standard for detecting small HCC nodules in cirrhotic livers due to its superior soft-tissue contrast and functional imaging capabilities.However,early or atypical presentations remain challenging for differential diagnosis,staging,and treatment planning.In these scenarios contrast-enhanced ultrasonography(CEUS)is a valuable second-line tool,offering real-time,radiation-free evaluation and repeatability for follow-up.A recent meta-analysis of head-to-head studies reported comparable diagnostic performance between CEUS and CT/MRI with pooled sensitivities and specificities of 0.67/0.88 for CEUS vs 0.60/0.98 for CT/MRI in non-HCC malignancies,and similar specificities for HCC diagnosis(0.70 for CEUS vs 0.59 for CT;0.81 for CEUS vs 0.79 for MRI)[1].Given the limitations of individual imaging modalities,hybrid techniques and multimodal approaches are gaining traction for improving lesion detection,especially in cases where standard methods fall short.Artificial intelligence(AI)has emerged as a powerful tool in medical imaging,enhancing diagnostic accuracy and reliability across platforms.In CEUS liver imaging dynamic enhancement patterns often challenge consistent interpretation across observers.AI holds particular promise for standardizing assessments.The growing complexity of liver tumor evaluation has also driven interest in approaches that integrate serum bio-markers with advanced imaging.However,no single strategy currently meets all the diagnostic and prognostic re-quirements.Recent studies highlighted the potential of AI to bridge this gap by enabling precise image interpretation and facilitating the integration of heterogeneous clinical and imaging data[2].Altogether the convergence of CEUS with AI and radiomics offers a dynamic,quantitative,and potentially reproducible paradigm for liver lesion assessment,comple-menting traditional imaging methods.This review aimed to provide an overview of current advances in AI-driven CEUS for liver lesion assessment with a particular focus on automated Liver Imaging Reporting and Data System(LI-RADS)classification,radiomics-based models,and future clinical integration.While another recent systematic review[3]provided a comprehensive analysis of AI applications in CEUS,our approach offers a targeted perspective,emphasizing LI-RADS-centered scoring,automated lesion characterization,and clinical utility,particularly in the context of HCC diagnosis and management.In the methodological process of this narrative mini-review,the literature selection was primarily based on targeted PubMed searches.ChatGPT-4o(OpenAI)[4]was employed to assist in refining query parameters and identifying relevant,up-to-date peer-reviewed sources on CEUS-based AI applications. 展开更多
关键词 Artificial intelligence Contrast-enhanced ultrasound Liver Imaging Reporting and Data System Hepatocellular carcinoma Deep learning Radiomics Clinical decision support systems Focal liver lesions Image interpretation Diagnostic workflow
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Exosomes as promising frontier approaches in future cancer therapy
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作者 Fatt-Yang Chew Chin-Hung Tsai +3 位作者 Kuang-Hsi Chang Yu-Kang Chang Ruey-Hwang Chou Yi-Jui Liu 《World Journal of Gastrointestinal Oncology》 SCIE 2025年第1期28-33,共6页
In this editorial,we will discuss the article by Tang et al published in the recent issue of the World Journal of Gastrointestinal Oncology.They explored an innovative approach to enhancing gemcitabine(GEM)delivery an... In this editorial,we will discuss the article by Tang et al published in the recent issue of the World Journal of Gastrointestinal Oncology.They explored an innovative approach to enhancing gemcitabine(GEM)delivery and efficacy using human bone marrow mesenchymal stem cells(HU-BMSCs)-derived exosomes.The manufacture of GEM-loaded HU-BMSCs-derived exosomes(Exo-GEM)has been optimized.The Tang et al’s study demonstrated that Exo-GEM exhibits enhanced cytotoxicity and apoptosis-inducing effects compared to free GEM,highlighting the potential of exosome-based drug delivery systems as a more effective and targeted approach to chemotherapy in pancreatic cancer.Additional in vivo studies are required to confirm the safety and effectiveness of Exo-GEM before it can be considered for clinical use. 展开更多
关键词 Mesenchymal stem cells EXOSOMES GEMCITABINE Pancreatic cancer APOPTOSIS
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Study of the Effect of Climate Variability on Hydroelectric Power Generation Capacity:The Case of the Garafiri Dam in Guinea
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作者 Souleymane Soumah Mohamed Ansoumane Camara +4 位作者 Bangaly Kourouma Moussa Mamady Traore Amadou Lamarana Bah Mouhamadou Falilou Ndiaye Vincent Sambou 《Journal of Energy and Power Engineering》 2025年第1期36-43,共8页
Hydroelectric power production from Garafiri dam and rainfall are essential elements with the observation of hydroelectric power production in West African power system,particularly in Guinea.This article focuses on t... Hydroelectric power production from Garafiri dam and rainfall are essential elements with the observation of hydroelectric power production in West African power system,particularly in Guinea.This article focuses on the study and the influence of climate variability on hydroelectric power production at Garafiri dam over 16-year period(2008-2023).The aim of this work is to show the correlation between rainfall anomalies and hydroelectric power production at Garafiri dam.The method used consists of calculating precipitation anomalies at Garafiri site and those for the production of hydroelectric power from Garafiri dam over the study period.This approach led us to calculate the anomalies,leading to the study on climatic variability,in order to establish correlation between rainfall and hydroelectric power dam’s production.The trend with the correlation found made it possible to carry out a significance test between these two variables.These results clearly show that rainfall in Garafiri site increases hydroelectric power production and vice versa,which explains the interdependence between these two parameters,i.e.climatic variability and hydroelectric power production. 展开更多
关键词 DAM Garafiri energy production RAINFALL HYDROELECTRICITY
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A high—speed automatic spectrometer based on a solid—state non—collinear acousto-optic tunable filter
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作者 朱建华 郑玉臣 《Chinese Optics Letters》 SCIE EI CAS CSCD 2003年第2期85-87,共3页
An automatic visible spectrometer based on a non-collinear acousto-optic tunable filter (AOTF) is constructed for high-speed spectrometry. Its spectral filtering characteristics, such as relationships between the radi... An automatic visible spectrometer based on a non-collinear acousto-optic tunable filter (AOTF) is constructed for high-speed spectrometry. Its spectral filtering characteristics, such as relationships between the radio-frequency (RF) driving frequency and the output central wavelength, the output bandwidth and the central wavelength, its typical spectral point spread function (PSF), and so on, are studied systematically. The preliminary measurement results of AOTF spectrometer show that it is a solid-state, high-speed, easily controllable by computer-programming, rugged and compact spectroscopic device in comparison with a conventional grating spectrometer, and has the potential for widespread spectrometric applications. 展开更多
关键词 AOTF state non collinear acousto-optic tunable filter speed automatic spectrometer based on a solid A high
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Oxidative stress and nitric oxide metabolism responses during prolonged high-altitude exposure in preterm born adults
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作者 Marie Chambion-Diaz Giorgio Manferdelli +4 位作者 Benjamin J.Narang Guido Giardini Tadej Debevec Vincent Pialoux Grégoire P.Millet 《Journal of Sport and Health Science》 2025年第4期135-142,共8页
Background: Prematurely-born individuals tend to exhibit higher resting oxidative stress, although evidence suggests they may be more resistant to acute hypoxia-induced redox balance alterations. We aimed to investiga... Background: Prematurely-born individuals tend to exhibit higher resting oxidative stress, although evidence suggests they may be more resistant to acute hypoxia-induced redox balance alterations. We aimed to investigate the redox balance changes across a 3-day hypobaric hypoxic exposure at 3375 m in healthy adults born preterm(gestational age ≤ 32 weeks) and their term-born(gestational age ≥ 38 weeks)counterparts.Methods: Resting venous blood was obtained in normoxia(prior to altitude exposure), immediately upon arrival to altitude, and the following 3mornings. Antioxidant(superoxide dismutase(SOD), catalase, glutathione peroxidase(GPx), and ferric reducing antioxidant power(FRAP)),pro-oxidant(xanthine oxidase(XO) and myeloperoxidase(MPO)) enzyme activity, oxidative stress markers(advanced oxidation protein product(AOPP) and malondialdehyde(MDA)), nitric oxide(NO) metabolites(nitrites, nitrates, and total nitrite and nitrate(NOx)), and nitrotyrosine were measured in plasma.Results: SOD increased only in the preterm group(p < 0.05). Catalase increased at arrival in preterm group(p < 0.05). XO activity increased at Day 3 for the preterm group, while it increased acutely(arrival and Day 1) in control group. MPO increased in both groups throughout the3 days(p < 0.05). AOPP only increased at arrival in the preterm(p < 0.05) whereas it decreased at arrival up to Day 3(p < 0.05) for control.MDA decreased in control group from arrival onward. Nitrotyrosine decreased in both groups(p < 0.05). Nitrites increased on Day 3(p < 0.05)in control group and decreased on Day 1(p < 0.05) in preterm group.Conclusion: These data indicate that antioxidant enzymes seem to increase immediately upon hypoxic exposure in preterm adults. Conversely, the blunted pro-oxidant enzyme response to prolonged hypoxia exposure suggests that these enzymes may be less sensitive in preterm individuals.These findings lend further support to the potential hypoxic preconditioning effect of preterm birth. 展开更多
关键词 Hypoxia Premature birth Antioxidant Oxidative stress ALTITUDE
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THE MECHANISM OF AUTOMATIC CONTROL WITH VARIABLE STRUCTURE-PARAMETERS
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作者 涂承媛 《Chinese Science Bulletin》 SCIE EI CAS 1991年第2期167-169,共3页
The general form of the dynamic response of a controlled process is shown in Fig. 1, where E is the deviation of the controlled variable U from its set-point value U<sub>0</sub> (i. e. E= U<sub>0<... The general form of the dynamic response of a controlled process is shown in Fig. 1, where E is the deviation of the controlled variable U from its set-point value U<sub>0</sub> (i. e. E= U<sub>0</sub>-U). For convenience in discussing, we transform the curve in Fig. 1 into that in Fig. 2 a t-domain curve of |E|. Now, we discuss a certain period of variation of the curve in Fig. 2, e.g. a time interval between to and t<sub>4</sub>.We partition this period of variation into four subintervals: t<sub>0</sub>—t<sub>1</sub>, t<sub>1</sub>—t<sub>2</sub>, t<sub>2</sub>—t<sub>3</sub> and t<sub>3</sub>—t<sub>4</sub>. It is easily seen that, in the first and the third subintervals, the rate of change 展开更多
关键词 deviation PARTITION CONVENIENCE brought unfavorable eliminate FOURTH weakened TENDENCY hence
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MECHANISM OF IMPLICIT DIFFERENTIATION AND IMPLICIT INTEGRATION IN AUTOMATIC CONTROL
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作者 涂承媛 《Chinese Science Bulletin》 SCIE EI CAS 1990年第11期962-964,共3页
PID control is widely used in various process control systems with a differentiation function aimed at acquiring a good transient response of the systems and with an integration function aimed at improving the static ... PID control is widely used in various process control systems with a differentiation function aimed at acquiring a good transient response of the systems and with an integration function aimed at improving the static characteristics of the systems so as to mini- 展开更多
关键词 aimed acquiring SATURATION EXTREME EXACT operations furthermore MULTISTAGE ATTACHED proportional
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