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Short bouts of accumulated exercise:Review and consensus statement on definition,efficacy,feasibility,practical applications,and future directions 被引量:1
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作者 Mingyue Yin Yongming Li +43 位作者 Abdul Rashid Aziz Aidan Buffey David J.Bishop Dapeng Bao George P.Nassis Hashim Islam Hongying Wang Jackson J.Fyfe Jianfang Xu Jianxiu Liu Jiexiu Zhao Jingwei Cao Jonathan P.Little Junqiang Qiu Keith M.Diaz Lijuan Wang Liye Zou Max J.Western Meynard L.Toledo Min Hu Minghui Quan Neville Owen Niels B.J.Vollaard Olivier Girard Qingde Shi Richard S.Metcalfe Rodrigo Ramirez-Campillo Ru Wang Waris Wongpipit Weimo Zhu Wenfei Zhu Weigang Xu Xiaochun Wang Xiaoping Chen Xiong Wang Xu Wen Yang Liu Ying Gao Yue Fu Zhaowei Kong Zhenbo Cao Zhengzhen Wang Peijie Chen Lijuan Mao 《Journal of Sport and Health Science》 2026年第2期1-30,共30页
Background:Insufficient physical activity and prolonged sedentary behavior have emerged as major global public health challenges.Short bouts(≤10 min)of accumulated exercise(SBAE)throughout the day may be a promising ... Background:Insufficient physical activity and prolonged sedentary behavior have emerged as major global public health challenges.Short bouts(≤10 min)of accumulated exercise(SBAE)throughout the day may be a promising strategy to mitigate the adverse effects of prolonged sitting and promote physical activity,ultimately promoting overall health.However,previous ambiguity in defining this concept has resulted in a fragmented and inconsistent evidence base,impeding practical applications,the development of guidelines,and policymaking.The purpose of this study is to establish an operational definition of SBAE by synthesizing systematic reviews and research trials alongside an expert consensus.Additionally,it seeks to evaluate acute and long-term efficacy and feasibility,providing evidence-based recommendations for practice and future research directions.Methods:A literature search was performed across PubMed and Web of Science,followed by systematic screening and summarization of eligible studies based on predefined inclusion criteria.Inclusion criteria encompassed various modes/types of SBAE(bouts lasting≤10 min,performed multiple times daily with≥30 min intervals);both aerobic and resistance exercise were considered.Relevant systematic reviews and research trials were included.Methodological quality,risk of bias,and evidence certainty were assessed.Expert consensus was obtained through a survey to evaluate recommendations and agreement levels on findings.Results:After analyzing 27 systematic reviews,135 research studies,and an expert consensus involving 48 researchers from 11 countries,SBAE is defined as any exercise mode of activity,regardless of intensity,that is accumulated in either continuous or intermittent bouts lasting≤10 min per session(including multiple intermittent sets)that are performed multiple times(≥2 sessions/day)per day,with intervals of≥30 min between bouts or otherwise sufficient time for recovery.When used to interrupt prolonged periods of sedentary time,SBAE mitigates the acute adverse effects of sedentary behavior on more than 10 clinical biomarkers of endocrine,cardiovascular,and brain health/function among adults of diverse ages and conditions.Moreover,SBAE was superior for improving acute glycemic control compared to a single continuous exercise session.As a long-term intervention(average of 11 weeks),SBAE can improve over 20 health outcomes,including peak oxygen uptake,resting blood pressure,and metabolic health.Additionally,SBAE might be more effective than continuous exercise for improving longer-term glycemic control and body composition.Long-term completion rates for SBAE interventions are generally high(95%),with low dropout rates(12%)and high adherence rates even without supervision(85%),and its safety has been preliminarily validated.Conclusion:An operational definition of SBAE is provided along with its classification and acute and long-term efficacy.Practical exercise prescription recommendations and evidence-based strategies for various populations and contexts are provided.Future research should focus on generating high-quality evidence for SBAE in 5 key areas:quantification and monitoring,population-specific responses,optimization of exercise prescriptions,intervention efficacy,and practical implementation.Additionally,addressing policy,environmental,and promotional barriers is crucial for transitioning from expert consensus to public consensus,and for facilitating the application of this strategy in real-world environments. 展开更多
关键词 Short bouts of accumulated exercise Exercise snacks Consensus statement Sedentary breaks
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Objectively measured 24-h movement behaviours of child-guardian pairs in low-to-middle income households in Nairobi City County,Kenya
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作者 Lucy-Joy Wachira Nils Swindell +9 位作者 Noora Kanerva Muhoro Munuhe Timo Vuorimaa Tiina Laiho Sophie Ochola Maijaliisa Erkkola George Owino Gareth Stratton Mikael Fogelholm Vincent Onywera 《Sports Medicine and Health Science》 2025年第4期263-271,共9页
Background The decreasing prevalence of physical activity(PA)among urban children in Sub-Saharan Africa is a growing public health concern.More emphasis should focus on examining the influence of parental PA behaviour... Background The decreasing prevalence of physical activity(PA)among urban children in Sub-Saharan Africa is a growing public health concern.More emphasis should focus on examining the influence of parental PA behaviour on the children’s PA patterns.We explored associations of 24hour(h)accelerometer-measured movement behaviours of guardian-child pairs in Nairobi City County,Kenya.Methods This cross-sectional study assessed 80 pairs consisting of children aged 9-14 years and their guardians in one area of low and one area of middle socioeconomic status(SES)(Embakasi Sub-County and Lang’ata Sub-County),in Nairobi City County,Kenya.The study used waist worn Tri-axial Actigraph(GT3X+and ActiSleep+)accelerometers to quantify PA and sedentary time(SED).Association between guardians'and children’s PA was examined using linear regression,adjusting for guardians'educational attainment and household wealth.Results Of the children,42(52.5%)and 76(96.2%)of the guardians were women.Children in low SES areas spent more time(p<0.001)in moderate-to-vigorous physical activity compared to children from middle SES area.The guardians in low SES area were younger and spent more time in light PA(p=0.036)while their counterparts had higher daily SED(p=0.049).Guardian’s SED associated with higher children’s SED(p=0.033)even after adjusting for guardians'educational attainment(p=0.032)and wealth(p=0.05).There was no association between guardians'and children’s MVPA.Conclusion Considered alongside the extant literature,these results suggest that health promotion strategies should aim to reduce parental SED time while also planning to increase children’s PA. 展开更多
关键词 24-h movement behaviour Accelerometer Adolescents PARENT Physical activity Socio-economic status
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A mixed-studies systematic review and meta-analysis of school-based interventions to promote physical activity and/or reduce sedentary time in children 被引量:2
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作者 Michelle Jones Emmanuel Defever +2 位作者 Ayland Letsinger James Steele Kelly A Mackintosh 《Journal of Sport and Health Science》 SCIE 2020年第1期3-17,102,共16页
Purpose:The aim of this mixed-studies systematic review was to ascertain the effectiveness of school-based interventions in increasing physical activity(PA) and/or reducing sedentary time(ST) in children aged 5-11 yea... Purpose:The aim of this mixed-studies systematic review was to ascertain the effectiveness of school-based interventions in increasing physical activity(PA) and/or reducing sedentary time(ST) in children aged 5-11 years,as well as to explore their effectiveness in relation to categories of the theory of expanded,extended,and enhanced opportunity(TEO).Methods:Adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA) guidelines,5 databases were searched using predefined search terms.Following title and abstract screening of 1115 records,the removal of duplicates(n=584) and articles that did not meet the inclusion criteria agreed to a priori(n=419) resulted in 112 records that were full-text screened.Two independent reviewers subsequently used the mixed-methods appraisal tool to assess the methodological quality of 57 full-text studies that met the inclusion criteria after full-text screening.The interventions were summarised using the TIDierR checklist and TEO.The strength of evidence was determined using a 5-level rating system utilising a published decision tree.Results:Overall evidence ratings for interventions implemented within school settings were:no evidence of effects on moderate-to-vigorous physical activity(MVPA) and inconclusive evidence of effects on sedentary time.In relation to the TEO,expansion of PA appeared to be the most promising intervention type for MVPA,with moderate evidence of effect,whereas extension and enhancement of PA opportunity demonstrated no evidence of effect.A critical issue of possible compensatory behavior was identified by analysis of intervention effect in relation to PA measurement duration;when studies measured changes in PA during the actual intervention,there was moderate evidence of effect,whereas those that measured changes in PA during the school day presented inconclusive evidence of effect,and those that measured changes in PA over a whole day yielded no evidence of effect.Two meta-analyses of those studies using a whole-day accelerometer measure for MVPA or ST showed a significant but moderate effect for MVPA(effect size=0.51;95% confidence interval(CI):0.02-0.99) and a large but nonsignificant effect for ST(effect size=1.15;95%CI:-1.03 to 3.33);both meta-analyses demonstrated low precision,considerable inconsistency,and high heterogeneity.Conclusion:The findings have important implications for future intervention research in terms of intervention design,implementation,and evaluation. 展开更多
关键词 CHILDREN INTERVENTION Physical activity SCHOOL Sedentary time
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Effect of high-intensity interval training in adolescents with asthma:The eXercise for Asthma with Commando Joe’s^(■)(X4ACJ)trial 被引量:1
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作者 Charles O.N.Winn Kelly A.Mackintosh +4 位作者 William T.B.Eddolls Gareth Stratton Andrew M.Wilson Melitta A.McNarry Gwyneth A.Davies 《Journal of Sport and Health Science》 SCIE 2021年第4期488-498,共11页
Background:Higher levels of cardiorespiratory fitness are associated with reduced asthma severity and increased quality of life in those with asthma.Therefore,the purpose of this study was to evaluate the effectivenes... Background:Higher levels of cardiorespiratory fitness are associated with reduced asthma severity and increased quality of life in those with asthma.Therefore,the purpose of this study was to evaluate the effectiveness of a 6-month high-intensity interval training(HIIT)intervention in adolescents with and without asthma.Methods:A total of 616 adolescents(334 boys;13.0±1.1 years,1.57±0.10 m,52.6±12.9 kg,mean±SD),including 155 with asthma(78 boys),were recruited as part of a randomized controlled trial from 5 schools(4 control and 1 intervention).The 221 intervention participants(116 boys;47 asthma)completed 6 months of school-based HIIT(30 min,3 times per week,10-30 s bouts at>90%age-predicted maximum heart rate with equal rest).At baseline,mid-intervention,post-intervention,and 3-month follow-up,measurements for 20-m shuttle run,body mass index(BMI),lung function,Pediatric Quality of Life Inventory,Paediatric Asthma Quality of Life Questionnaire,and Asthma Control Questionnaire were collected.Additionally,69 adolescents(39 boys(of the 36 with asthma there were 21 boys))also completed an incremental ramp test.For analysis,each group’s data(intervention and control)were divided into those with and without asthma.Results:Participants with asthma did not differ from their peers in any parameter of aerobic fitness,at any time-point,but were characterized by a greater BMI.The intervention elicited a significant improvement in maximal aerobic fitness but no change in sub-maximal parameters of aerobic fitness,lung function,or quality of life irrespective of asthma status.Those in the intervention group maintained their BMI,whereas BMI significantly increased in the control group throughout the 6-month period.Conclusion:HIIT represents an effective tool for improving aerobic fitness and maintaining BMI in adolescents,irrespective of asthma status.HIIT was well-tolerated by those with asthma,who evidenced a similar aerobic fitness to their healthy peers and responded equally well to a HIIT program. 展开更多
关键词 Body mass index Cardiorespiratory fitness Intermittent exercise INTERVENTION Quality of life
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Cerebral and muscle tissue oxygenation during exercise in healthy adults: A systematic review 被引量:1
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作者 Diego Orcioli-Silva Victor Spiandor Beretta +5 位作者 Paulo Cezar Rocha Santos Felipe Marroni Rasteiro Anita Brum Marostegan Rodrigo Vitorio Claudio Alexandre Gobatto Fulvia Barros Manchado-Gobatto 《Journal of Sport and Health Science》 SCIE CAS CSCD 2024年第4期459-471,F0003,共14页
Background:Near-infrared spectroscopy(NIRS)technology has allowed for the measurement of cerebral and skeletal muscle oxygenation simultaneously during exercise.Since this technology has been growing and is now succes... Background:Near-infrared spectroscopy(NIRS)technology has allowed for the measurement of cerebral and skeletal muscle oxygenation simultaneously during exercise.Since this technology has been growing and is now successfully used in laboratory and sports settings,this systematic review aimed to synthesize the evidence and enhance an integrative understanding of bloodflow adjustments and oxygen(O_(2))changes(i.e.,the balance between O_(2) delivery and O_(2) consumption)within the cerebral and muscle systems during exercise.Methods:A systematic review was conducted using PubMed,Embase,Scopus,and Web of Science databases to search for relevant studies that simultaneously investigated cerebral and muscle hemodynamic changes using the near-infrared spectroscopy system during exercise.This review considered manuscripts written in English and available before February 9,2023.Each step of screening involved evaluation by 2 inde-pendent authors,with disagreements resolved by a third author.The Joanna Briggs Institute Critical Appraisal Checklist was used to assess the methodological quality of the studies.Results:Twenty studies were included,of which 80%had good methodological quality,and involved 290 young or middle-aged adults.Different types of exercises were used to assess cerebral and muscle hemodynamic changes,such as cycling(n=11),treadmill(n=1),knee extension(n=5),isometric contraction of biceps brachii(n=3),and duet swim routines(n=1).The cerebral hemodynamics anal-ysis was focused on the frontal cortex(n=20),while in the muscle,the analysis involved vastus lateralis(n=18),gastrocnemius(n=3),biceps brachii(n=5),deltoid(n=1),and intercostal muscle(n=1).Overall,muscle deoxygenation increases during exercise,reaching a plateau in voluntary exhaustion,while in the brain,oxyhemoglobin concentration increases with exercise intensity,reaching a plateau or declining at the exhaustion point.Conclusion:Muscle and cerebral oxygenation respond differently to exercise,with muscle increasing O_(2) utilization and cerebral tissue increasing O_(2) delivery during exercise.However,at the exhaustion point,both muscle and cerebral oxygenation become compromised.This is characterized by a reduction in bloodflow and a decrease in O_(2) extraction in the muscle,while in the brain,oxygenation reaches a plateau or decline,potentially resulting in motor failure during exercise. 展开更多
关键词 Near-infrared spectroscopy HEMODYNAMIC Blood flow BRAIN Muscle metabolism
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Are flexibility and muscle-strengthening activities associated with functional limitation? 被引量:1
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作者 Craig E.Pfeifer Leanna M.Ross +2 位作者 Samantha R.Weber Xuemei Sui Steven N.Blair 《Sports Medicine and Health Science》 2022年第2期95-100,共6页
This retrospective cohort study examined the relationship between self-reported participation in flexibility and muscular strengthening activities and the development of functional limitation(i.e.,once an individual h... This retrospective cohort study examined the relationship between self-reported participation in flexibility and muscular strengthening activities and the development of functional limitation(i.e.,once an individual has difficulty with or becomes unable to perform activities of daily living).Data were obtained from 1318 adults(mean age 49.59.7 years;98.7%Caucasian;14.9%female)enrolled in the Aerobics Center Longitudinal Study from 1979 to 2004 and free of functional limitation at baseline.Mail-back health surveys were used to prospectively determine incident functional limitation.Participation in muscle-strengthening and flexibility activities was assessed via self-report.Adjusted logistic regression analyses were used to determine the odds ratios(OR)and corresponding 95%confidence intervals for developing functional limitation during follow-up based on participation in general and specific categories of flexibility(‘Stretching’,‘Calisthenics’,or‘Exercise Class’)and musclestrengthening activities(‘Calisthenics’,‘Free Weights’,‘Weight Training Machines’,or‘Other’).Overall,42.6%of the sample reported incident functional limitation.After adjusting for potential confounders(e.g.,age,sex,cardiometabolic risk factors),those who reported performing muscle-strengthening activities in general(n=685)were at lower risk of developing functional limitation[OR=0.79(0.63–1.00)].In addition,the specific flexibility activities of stretching(n=491)and calisthenics(n=122)were associated with 24%and 38%decreased odds of incident functional limitation,respectively.General muscle-strengthening,stretching,and calisthenics activities are prospectively associated with decreased risk of incident functional limitation in generally healthy,middleaged and older adults.Thus,both public health and rehabilitation programs should highlight the importance of flexibility and muscle-strengthening activities during adulthood to help preserve functional capacity. 展开更多
关键词 Functional capacity Quality of life AGING EXERCISE INDEPENDENCE Health
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Back to school after lockdown: The effect of COVID-19 restrictions on children’s device-based physical activity metrics
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作者 Liezel Hurter Melitta McNarry +1 位作者 Gareth Stratton Kelly Mackintosh 《Journal of Sport and Health Science》 SCIE 2022年第4期530-536,共7页
Background:The coronavirus disease-2019(COVID-19) pandemic and national lockdowns took away opportunities for children to be physically active.This study aimed to determine the effect of the COVID-19 lockdown on accel... Background:The coronavirus disease-2019(COVID-19) pandemic and national lockdowns took away opportunities for children to be physically active.This study aimed to determine the effect of the COVID-19 lockdown on accelerometer-assessed physical activity(PA) in children in Wales.Methods:Eight hundred participants(8-18 years old),stratified by sex,age,and socio-economic status,wore Axivity AX3 accelerometers for7 days in February 2021,during the lockdown,and in May 2021,while in school.Raw accelerometer data were processed in R-package GGIR,and cut-point data,average acceleration(AvAcc),intensity gradient,and the acceleration above which the most active X minutes are accumulated(MX) metrics were extracted.Linear mixed models were used to assess the influence of time-point,sex,age,and socioeconomic status(SES) on PA.Results:During lockdown,moderate-to-vigorous PA was 38.4±24.3 min/day;sedentary time was 849.4±196.6 min/day;mean± SD.PA levels increased significantly upon return to school(all variables p <0.001).While there were no sex differences during lockdown(p=0.233),girls engaged in significantly less moderate-to-vigorous PA than boys once back in school(p <0.001).Furthermore,boys had more favorable intensity profiles than girls(intensity gradient:p <0.001),regardless of time-point.PA levels decreased with age at both time-points;upper secondary school girls were the least active group,with an average M30 of 195.2 mg(while in school).Conclusion:The lockdown affected boys more than girls,as reflected by the disappearance of the typical sex difference in PA levels during lockdown,although these were re-established on return to school.Upper secondary school(especially girls) might need specific COVID-recovery intervention. 展开更多
关键词 ACCELEROMETER Intensity gradient MX metrics
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Physiological and perceptual responses to sprint interval exercise using arm versus leg cycling ergometry
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作者 Todd A.Astorino Shealin Pierce +2 位作者 Madisen B.Piva Richard S.Metcalfe Niels B.J.Vollaard 《Sports Medicine and Health Science》 2024年第4期385-393,共9页
Increases in power output and maximal oxygen consumption(V_O2max)occur in response to sprint interval exercise(SIE),but common use of“all-out”intensities presents a barrier for many adults.Furthermore,lower-body SIE... Increases in power output and maximal oxygen consumption(V_O2max)occur in response to sprint interval exercise(SIE),but common use of“all-out”intensities presents a barrier for many adults.Furthermore,lower-body SIE is not feasible for all adults.We compared physiological and perceptual responses to supramaximal,but“nonall-out”SIE between leg and arm cycling exercise.Twenty-four active adults(mean±SD age:[25±7]y;cycling VO_(2)max:[39±7]mL·kg^(-1)·min^(-1))performed incremental exercise using leg(LCE)and arm cycle ergometry(ACE)to determine VO_(2)max and maximal work capacity(Wmax).Subsequently,they performed four 20 s bouts of SIE at 130% Wmax on the LCE or ACE at cadence=120-130 rev/min,with 2 min recovery between intervals.Gas exchange data,heart rate(HR),blood lactate concentration(BLa),rating of perceived exertion(RPE),and affective valence were acquired.Data showed significantly lower(p<0.001)absolute mean([1.24±0.31]L·min^(-1) vs.[1.59±0.34]L·min^(-1);d=1.08)and peak VO_(2)([1.79±0.48]L·min^(-1) vs.[2.10±0.44]L·min^(-1);d=0.70)with ACE versus LCE.However,ACE elicited significantly higher(p<0.001)relative mean([62%±9%]VO_(2)max vs.[57%±7%]VO_(2)max,d=0.63)and peak VO_(2)([88%±10%]VO_(2)max vs.[75%±10%]VO_(2)max,d?1.33).Post-exercise BLa was significantly higher([7.0±1.7]mM vs.[5.7±1.5]mM,p=0.024,d?0.83)for LCE versus ACE.There was no significant effect of modality on RPE or affective valence(p>0.42),and lowest affective valence recorded(2.0±1.8)was considered“good to fairly good”.Data show that non“all-out”ACE elicits lower absolute but higher relative HR and VO_(2) compared to LCE.Less aversive perceptual responses could make this non-all-out modality feasible for inactive adults. 展开更多
关键词 High intensity interval training Upper body exercise Peak power output Oxygen uptake Blood lactate concentration
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Reflections on Long-Term Development and Use of Automated Scoring Technology in a Sport (Modified Boxing) Context
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作者 Paul Perkins Richard J. N. Helmer +1 位作者 Colin Mackintosh Allan G. Hahn 《World Journal of Engineering and Technology》 2017年第3期455-480,共26页
Technology is being increasingly used to aid judging in sport, but its employment as the primary means of scoring is rare. We have developed and implemented a fully automated scoring system in the context of a modifie... Technology is being increasingly used to aid judging in sport, but its employment as the primary means of scoring is rare. We have developed and implemented a fully automated scoring system in the context of a modified, low-risk form of boxing. The system, which requires contestants to wear vests and gloves incorporating sensor fabrics, has been used in multiple settings over the past five years. During that period, it has undergone progressive iteration guided by action research methodology. Here, we summarise that iteration, reflect on present status and identify possible future directions. We have found that concept of automated scoring has wide appeal, and the wearable technology is almost universally considered comfortable. Nevertheless, some issues remain to be addressed. Use of the technology requires considerable prior and subsequent commitment of time. Apparently valid contacts occasionally fail to score. Causative factors include the configuration of electrical circuitry in the vests and deterioration of that circuitry with repeated vest use and washing. Also, false positive scores are sometimes generated by vest self-shorting and effects of sweat. Many contestants adopt unorthodox styles aimed at exploiting the characteristics of the automated scoring methodology, affecting the aesthetics of the modified sport. There is an expectation that technologically-based scoring should have much greater accuracy than human judging, and should be essentially fail-proof. Disillusionment can occur in?situations where this expectation is not met. We have identified potential?solutions to all the existing issues, with some now being actively explored. Continuation of the quest seems justified by popular dissatisfaction with subjective human judging of boxing and other sports, but we have come to realise that purely technological judging can introduce unforeseen complexities. Our observations could be relevant to various sports interested in the notion of technological judging. 展开更多
关键词 AUTOMATED SCORING TECHNOLOGY Box’Tag Smart Fabric SPORT TECHNOLOGY Wearable Sensors
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A 24 hour naproxen dose on gastrointestinal distress and performance during cycling in the heat
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作者 Dawn M.Emerson J.Mark Davis +5 位作者 Stephen CL.Chen Toni M.Torres-McGehee Craig E.Pfeifer Charles C.Emerson Joseph D.Bivona Justin V.Stone 《Sports Medicine and Health Science》 2020年第1期19-24,共6页
Using a double-blind,randomized and counterbalanced,cross-over design,we assessed naproxen's effects on gastrointestinal(GI)distress and performance in eleven volunteers(6 male,5 female).Participants completed 4 t... Using a double-blind,randomized and counterbalanced,cross-over design,we assessed naproxen's effects on gastrointestinal(GI)distress and performance in eleven volunteers(6 male,5 female).Participants completed 4 trials:1)placebo and ambient);2)placebo and heat;3)naproxen and ambient;and 4)naproxen and heat.Independent variables were one placebo or 220 mg naproxen pill every 8 h(h)for 24 h and ambient(22.7±1.8℃)or thermal environment(35.7±1.3℃).Participants cycled 80 min at a steady heart rate then 10 min for maximum distance.Perceived exertion was measured throughout cycling.Gastrointestinal distress was assessed pre-,during,post-,3 h post-,and 24 h post-cycling using a GI index for upper,lower,and systemic symptoms.No statistically significant differences occurred between conditions at any time for GI symptoms or perceived exertion,distance,or heart rate during maximum effort.A 24 h naproxen dose did not significantly affect performance or cause more frequent or serious GI distress when participants were euhydrated and cycling at moderate intensity in a thermal environment. 展开更多
关键词 NSAID Gastrointestinal bleeding Heart rate Perceived exertion
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An acute naproxen dose does not affect core temperature or Interleukin-6 during cycling in a hot environment
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作者 Dawn M.Emerson Stephen CL.Chen +3 位作者 Toni M.Torres-McGehee Craig E.Pfeifer Charles C.Emerson J.Mark Davis 《Sports Medicine and Health Science》 2021年第4期243-251,共9页
Non-steroidal anti-inflammatory drugs’anti-pyretic and anti-inflammatory effects has led some individuals to theorize these medications may blunt core body temperature(Tc)increases during exercise.We utilized a doubl... Non-steroidal anti-inflammatory drugs’anti-pyretic and anti-inflammatory effects has led some individuals to theorize these medications may blunt core body temperature(Tc)increases during exercise.We utilized a double-blind,randomized,and counterbalanced cross-over design to examine the effects of a 24-h naproxen dose(3–220 mg naproxen pills)and placebo(0 mg naproxen)on Tc and plasma interleukin-6(IL-6)concentrations during cycling in a hot or ambient environment.Participants(n=11;6 male,5 female;age=27.8±6.5 years,weight=79.1±17.9 kg,height=177±9.5 cm)completed 4 conditions:1)placebo and ambient(Control);2)placebo and heat(Heat);3)naproxen and ambient(Npx);and 4)naproxen and heat(NpxHeat).Dependent measures were taken before,during,and immediately after 90 min of cycling and then 3 h after cycling.Overall,Tc significantly increased pre-(37.1±0.4℃)to post-cycling(38.2±0.3℃,F_(1.7,67.3)=150.5,p<0.001)and decreased during rest(37.0±0.3℃,F_(2.0,81.5)=201.6,p<0.001).Rate of change or maximum Tc were not significantly different between conditions.IL-6 increased pre-(0.54±0.06 pg/ml)to post-exercise(2.46±0.28 pg/ml,p<0.001)and remained significantly higher than pre-at 3 h post-(1.17±0.14 pg/ml,95%CI=-1.01 to-0.23,p=0.001).No significant IL-6 differences occurred between conditions.A 24-h,over-the-counter naproxen dose did not significantly affect Tc or IL-6 among males and females cycling in hot or ambient environments. 展开更多
关键词 CYTOKINE Exertional heat illness NSAIDS THERMOREGULATION Exercise
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