In recent years,rapid urbanization has had a profound impact on landscape stability.As a typical example of China's rapid urbanization,Hangzhou has also experienced significant landscape changes,which have profoun...In recent years,rapid urbanization has had a profound impact on landscape stability.As a typical example of China's rapid urbanization,Hangzhou has also experienced significant landscape changes,which have profoundly affected its ecological stability.Taking Hangzhou as an example,this study integrates land use change data from 1980 to 2020,combines dynamic simulation and ecological modeling techniques,and carries out a comprehensive analysis of historical trends and future predictions,to provide valuable insights into the complex interactions between urban expansion and landscape stability.The results indicate that:1)between 1980 and2020,Hangzhou experienced a significant increase in construction land at the expense of arable land,leading to a gradual decline in landscape stability,though the downward trend has slowed in recent years.2)The spatial distribution of landscape stability shows clear aggregation patterns,with lower stability concentrated in economically active flatlands and higher stability in the mountainous western regions.3)By 2040,further urban expansion is predicted to occur alongside increased landscape integration,reflecting the positive effects of ecological protection strategies.This study highlights the universal challenges of balancing economic growth with ecological stability in rapidly urbanizing regions.The combination of advanced simulation models and spatiotemporal analysis demonstrates a replicable framework for assessing urban expansion's ecological impacts.These findings underscore the importance of tailoring urban planning and ecological policies to address regional disparities,providing valuable insights for sustainable urban development and landscape management globally.展开更多
Recently,we read a retrospective study by Chen et al,which demonstrated that electroacupuncture is highly effective in relieving pain due to rotator cuff injuries and accelerating the recovery of shoulder function,pro...Recently,we read a retrospective study by Chen et al,which demonstrated that electroacupuncture is highly effective in relieving pain due to rotator cuff injuries and accelerating the recovery of shoulder function,promoting repair of rotator cuff injuries.This study provides a new way to the conservative treatment of early rotator cuff injuries.In the present letter,we review the current treatment of rotator cuff injury with electroacupuncture combined with rehabilitation techniques and propose our views.展开更多
Recently,we read an article published by the Yang et al.The results of this study indicated that engineered exosomes loaded with microRNA-29a(miR-29a)alleviate knee inflammation and maintain extracellular matrix stabi...Recently,we read an article published by the Yang et al.The results of this study indicated that engineered exosomes loaded with microRNA-29a(miR-29a)alleviate knee inflammation and maintain extracellular matrix stability in Sprague Dawley rats.The study’s results provide useful information for treating knee osteoarthritis(KOA).This letter,shares our perspectives on treating KOA using engineered exosomes for miR-29a.展开更多
In our experience patients undergoing circumcision are mostly concerned about pain and penile appearances. We conducted a prospective randomized trial to assess the benefits of a new disposable circumcision suture dev...In our experience patients undergoing circumcision are mostly concerned about pain and penile appearances. We conducted a prospective randomized trial to assess the benefits of a new disposable circumcision suture device （DCSD）. A total of 942 patients were equally divided into three groups （conventional circumcision, Shang ring and disposable suture device group）. Patients in the DCSD group were anesthetized with compound 5% lidocaine cream, the others with a 2% lidocaine penile block. Operation time, intra-operative blood loss, incision healing time, intra-operative and post-operative pain, the penile appearance and overall satisfaction degree were measured. Operation time and intra-operative blood loss were significantly lower in the Shang ring and suture device groups compared to the conventional group （P 〈 0.001）. Intra-operative pain was less in the suture device group compared With the other two groups （P 〈 0.001）; whereas post-operative pain was higher in the conventional group compared to the other two groups （P 〈 0.001）. Patients in the suture device （80.57%） and Shang ring （73,57%） groups were more satisfied with penile appearances compared with the conventional circumcision group （20.06%, P 〈 0.05）. Patients in suture device group also healed markedly faster than the conventional group （P 〈 0.01）. The overall satisfaction rate was better in the suture device group （78.66%） compared with the conventional （47.13%） and Shang ring （50.00%） groups （P 〈 0.05）. The combination of DCSD and lidocaine cream resulted in shorter operation and incision healing times, reduced intra-operative and post-operative pain and improved patient satisfaction with the cosmetic appearances.展开更多
Objective:To investigate the effect of a clinical nursing pathway and visual health education on patients with perianal abscesses was the objective of this study.Methods:Eighty patients with perianal abscesses undergo...Objective:To investigate the effect of a clinical nursing pathway and visual health education on patients with perianal abscesses was the objective of this study.Methods:Eighty patients with perianal abscesses undergoing in-patient surgical treatment(blinded for review)between December 2019 and November 2020 were divided randomly and evenly into a control group and an experimental group.The control group received routine nursing care,and the experimental group received visual health education nursing care.Digital pain scores,patient satisfaction scores,nursing quality scores,and scores measuring knowledge of perianal abscess disease for the two groups before and after nursing care were compared and analyzed.Results:The experimental group had visual analog scale(VAS)scores significantly lower than those of the control group(P<0.05).For total nursing satisfaction,the experimental group demonstrated a higher satisfaction rate(P<0.05).Clinical nursing quality scores were significantly higher in the experimental group than those in the control group(P<0.05).The perianal abscess disease-related knowledge scores after intervention were significantly higher in the experimental group than those in the control group(P<0.01).Conclusions:Visual health education nursing can help patients better understand and deal with perianal abscess disease.展开更多
Background:As a common breast disease in lactating women,lactational mastitis is clinically manifested as painful breast lumps and systemic symptoms.To a certain extent,this disease may affect the physical and mental ...Background:As a common breast disease in lactating women,lactational mastitis is clinically manifested as painful breast lumps and systemic symptoms.To a certain extent,this disease may affect the physical and mental health of lactating women and even the breastfeeding of infants.Objective:This study was conducted to evaluate the clinical efficacy of Lou’s Wentong Method in the comprehensive treatment of lactational mastitis and its effects on relevant symptoms.Methods:A total of 158 patients who were diagnosed with lactational mastitis in The First Affiliated Hospital of Zhejiang Chinese Medical University from January 2022 to January 2024 were included in this study to conduct a retrospective analysis.The treatment method comprised oral administration of traditional Chinese medicine prescriptions guided by the concept of“Wentong zhi yong”(warming and dispersing therapy for treating abscesses),puncture and pus extraction for patients with abscess formation,and milk drainage for patients with milk stagnation.The clinical symptoms of these patients were collected according to the seven indexes in Lou’s quantitative scorecard for evaluating the condition of canker sores before and after treatment.Additionally,the improvement of each symptom after treatment,the total effective rate of the clinical treatment,and the total symptom evaluation score before and after treatment were also analyzed.Results:It was demonstrated that there were significant differences in the overall distribution of different severity symptoms(skin erythema,breast pain,number of lumps,size of lumps,breast abscesses,and body temperature)at three time points(P<0.01).The evaluation of these symptoms at different time points revealed that all symptoms were effectively mitigated over time.Meanwhile,the efficacy was assessed according to the efficacy index to evaluate the efficacy of Lou’s Wentong Method in the comprehensive treatment of lactational mastitis.The results corroborated the pronounced efficacy of Lou’s Wentong Method in treating lactational mastitis,exhibiting statistical significance(P<0.01).Conclusion:Lou’s Wentong Method has significant therapeutic effects in the comprehensive treatment of lactational mastitis.Furthermore,this method is conducive to alleviating the clinical symptoms of these patients as soon as possible and can reduce the pain of patients,thus promoting their recovery.展开更多
To the Editor:Despite major advances in medical care,the incidence and mortality of bloodstream infection(BSI)remain high,which is still a global public health challenge.BSI can be caused by various microorganisms,and...To the Editor:Despite major advances in medical care,the incidence and mortality of bloodstream infection(BSI)remain high,which is still a global public health challenge.BSI can be caused by various microorganisms,and the most common organisms are Escherichia coli,Klebsiella pneumoniae,and Staphylococcus aureus(S.aureus),according to the China Antimicrobial Surveillance Network(CHINET).[1]S.aureus is the third most common cause of BSI,which is associated with shortterm mortality rates of 15–30%,long-term excess mortality,and increased healthcare costs.At present,there are many studies on Gram-negative bacteremia but relatively few on S.aureus bloodstream infection(SA-BSI),especially in China.With the occurrence of new treatments and clinical conditions,such as aging and extensive antibiotic resistance,it is necessary to reanalyze the clinical characteristics and prognosis of SA-BSI.展开更多
基金Under the auspices of Zhejiang Provincial Natural Science Foundation of China(No.LY19C160007)。
文摘In recent years,rapid urbanization has had a profound impact on landscape stability.As a typical example of China's rapid urbanization,Hangzhou has also experienced significant landscape changes,which have profoundly affected its ecological stability.Taking Hangzhou as an example,this study integrates land use change data from 1980 to 2020,combines dynamic simulation and ecological modeling techniques,and carries out a comprehensive analysis of historical trends and future predictions,to provide valuable insights into the complex interactions between urban expansion and landscape stability.The results indicate that:1)between 1980 and2020,Hangzhou experienced a significant increase in construction land at the expense of arable land,leading to a gradual decline in landscape stability,though the downward trend has slowed in recent years.2)The spatial distribution of landscape stability shows clear aggregation patterns,with lower stability concentrated in economically active flatlands and higher stability in the mountainous western regions.3)By 2040,further urban expansion is predicted to occur alongside increased landscape integration,reflecting the positive effects of ecological protection strategies.This study highlights the universal challenges of balancing economic growth with ecological stability in rapidly urbanizing regions.The combination of advanced simulation models and spatiotemporal analysis demonstrates a replicable framework for assessing urban expansion's ecological impacts.These findings underscore the importance of tailoring urban planning and ecological policies to address regional disparities,providing valuable insights for sustainable urban development and landscape management globally.
基金Supported by Zhejiang Administration of Traditional Chinese Medicine,No.2023ZF019Natural Science Foundation of Zhejiang Province,No.(2020)56+1 种基金Cultivation of Health High-level Talents in Zhejiang Province in 2022,No.(2019)58and National Natural Science Foundation of China,No.H02710.
文摘Recently,we read a retrospective study by Chen et al,which demonstrated that electroacupuncture is highly effective in relieving pain due to rotator cuff injuries and accelerating the recovery of shoulder function,promoting repair of rotator cuff injuries.This study provides a new way to the conservative treatment of early rotator cuff injuries.In the present letter,we review the current treatment of rotator cuff injury with electroacupuncture combined with rehabilitation techniques and propose our views.
基金National Natural Science Foundation of China,No.82074469.
文摘Recently,we read an article published by the Yang et al.The results of this study indicated that engineered exosomes loaded with microRNA-29a(miR-29a)alleviate knee inflammation and maintain extracellular matrix stability in Sprague Dawley rats.The study’s results provide useful information for treating knee osteoarthritis(KOA).This letter,shares our perspectives on treating KOA using engineered exosomes for miR-29a.
文摘In our experience patients undergoing circumcision are mostly concerned about pain and penile appearances. We conducted a prospective randomized trial to assess the benefits of a new disposable circumcision suture device （DCSD）. A total of 942 patients were equally divided into three groups （conventional circumcision, Shang ring and disposable suture device group）. Patients in the DCSD group were anesthetized with compound 5% lidocaine cream, the others with a 2% lidocaine penile block. Operation time, intra-operative blood loss, incision healing time, intra-operative and post-operative pain, the penile appearance and overall satisfaction degree were measured. Operation time and intra-operative blood loss were significantly lower in the Shang ring and suture device groups compared to the conventional group （P 〈 0.001）. Intra-operative pain was less in the suture device group compared With the other two groups （P 〈 0.001）; whereas post-operative pain was higher in the conventional group compared to the other two groups （P 〈 0.001）. Patients in the suture device （80.57%） and Shang ring （73,57%） groups were more satisfied with penile appearances compared with the conventional circumcision group （20.06%, P 〈 0.05）. Patients in suture device group also healed markedly faster than the conventional group （P 〈 0.01）. The overall satisfaction rate was better in the suture device group （78.66%） compared with the conventional （47.13%） and Shang ring （50.00%） groups （P 〈 0.05）. The combination of DCSD and lidocaine cream resulted in shorter operation and incision healing times, reduced intra-operative and post-operative pain and improved patient satisfaction with the cosmetic appearances.
基金supported by the First Affiliated Hospital of Huzhou Teachers College(No.2019GYB44)。
文摘Objective:To investigate the effect of a clinical nursing pathway and visual health education on patients with perianal abscesses was the objective of this study.Methods:Eighty patients with perianal abscesses undergoing in-patient surgical treatment(blinded for review)between December 2019 and November 2020 were divided randomly and evenly into a control group and an experimental group.The control group received routine nursing care,and the experimental group received visual health education nursing care.Digital pain scores,patient satisfaction scores,nursing quality scores,and scores measuring knowledge of perianal abscess disease for the two groups before and after nursing care were compared and analyzed.Results:The experimental group had visual analog scale(VAS)scores significantly lower than those of the control group(P<0.05).For total nursing satisfaction,the experimental group demonstrated a higher satisfaction rate(P<0.05).Clinical nursing quality scores were significantly higher in the experimental group than those in the control group(P<0.05).The perianal abscess disease-related knowledge scores after intervention were significantly higher in the experimental group than those in the control group(P<0.01).Conclusions:Visual health education nursing can help patients better understand and deal with perianal abscess disease.
基金supported by the Zhejiang Provincial Administration of Traditional Chinese Medicine,the national medical masters inheritance studio construction project(GZS2021006).
文摘Background:As a common breast disease in lactating women,lactational mastitis is clinically manifested as painful breast lumps and systemic symptoms.To a certain extent,this disease may affect the physical and mental health of lactating women and even the breastfeeding of infants.Objective:This study was conducted to evaluate the clinical efficacy of Lou’s Wentong Method in the comprehensive treatment of lactational mastitis and its effects on relevant symptoms.Methods:A total of 158 patients who were diagnosed with lactational mastitis in The First Affiliated Hospital of Zhejiang Chinese Medical University from January 2022 to January 2024 were included in this study to conduct a retrospective analysis.The treatment method comprised oral administration of traditional Chinese medicine prescriptions guided by the concept of“Wentong zhi yong”(warming and dispersing therapy for treating abscesses),puncture and pus extraction for patients with abscess formation,and milk drainage for patients with milk stagnation.The clinical symptoms of these patients were collected according to the seven indexes in Lou’s quantitative scorecard for evaluating the condition of canker sores before and after treatment.Additionally,the improvement of each symptom after treatment,the total effective rate of the clinical treatment,and the total symptom evaluation score before and after treatment were also analyzed.Results:It was demonstrated that there were significant differences in the overall distribution of different severity symptoms(skin erythema,breast pain,number of lumps,size of lumps,breast abscesses,and body temperature)at three time points(P<0.01).The evaluation of these symptoms at different time points revealed that all symptoms were effectively mitigated over time.Meanwhile,the efficacy was assessed according to the efficacy index to evaluate the efficacy of Lou’s Wentong Method in the comprehensive treatment of lactational mastitis.The results corroborated the pronounced efficacy of Lou’s Wentong Method in treating lactational mastitis,exhibiting statistical significance(P<0.01).Conclusion:Lou’s Wentong Method has significant therapeutic effects in the comprehensive treatment of lactational mastitis.Furthermore,this method is conducive to alleviating the clinical symptoms of these patients as soon as possible and can reduce the pain of patients,thus promoting their recovery.
基金National Natural Science Foundation of China(No.81901941)Natural Science Foundation of Zhejiang Province(No.LY19H150007,No.LY20H150008)Medical and Health Research Program of Zhejiang Province(No.2019RC038,No.2018KY427,No.2022KY1396,No.2022KY1398)
文摘To the Editor:Despite major advances in medical care,the incidence and mortality of bloodstream infection(BSI)remain high,which is still a global public health challenge.BSI can be caused by various microorganisms,and the most common organisms are Escherichia coli,Klebsiella pneumoniae,and Staphylococcus aureus(S.aureus),according to the China Antimicrobial Surveillance Network(CHINET).[1]S.aureus is the third most common cause of BSI,which is associated with shortterm mortality rates of 15–30%,long-term excess mortality,and increased healthcare costs.At present,there are many studies on Gram-negative bacteremia but relatively few on S.aureus bloodstream infection(SA-BSI),especially in China.With the occurrence of new treatments and clinical conditions,such as aging and extensive antibiotic resistance,it is necessary to reanalyze the clinical characteristics and prognosis of SA-BSI.
