The construction of local applied colleges and universities has always been an important part of the construction and development of higher education in China. As a representative local applied undergraduate college i...The construction of local applied colleges and universities has always been an important part of the construction and development of higher education in China. As a representative local applied undergraduate college in Anhui Province, West Anhui University has actively explored and practiced the construction of "second classroom" education system since September 2017, which has played a positive role in promoting the school teaching reform and the all-round development of collaborative education, but there are some problems in the practice. Using the big data of "Second Classroom" activities in West Anhui University, this paper analyzes the data of "Second Classroom" activities of students of grade 2020 and 2021 by using data mining technology. From the analysis results, it can be seen that there are some problems in "Second Classroom" activities in schools, such as unclear local characteristics, uneven curriculum distribution, uneven curriculum quality, and different participation in different types of activities, etc., and some corresponding suggestions are put forward in order to build a scientific system design, management system and curriculum arrangement.展开更多
The investigation and analysis of woody plants on the campus of Anhui Xinhua University reveals the presence of 103 species distributed across 43 families and 78 genera.Notably,depauperate families and monotypic gener...The investigation and analysis of woody plants on the campus of Anhui Xinhua University reveals the presence of 103 species distributed across 43 families and 78 genera.Notably,depauperate families and monotypic genera are found to be the most numerous.Among the families,Rosaceae is identified as the most diverse,encompassing a total of 21 species,while Prunus is found to contain the highest number of species,totaling 5.The geographic component of the plant flora is intricate and encompasses a wide range of distribution types,with a predominance of both tropic and temperate plants.展开更多
Hyla tsinlingensis(Hu et al.,1966)is endemic to China,and is widely distributed in the Qinling and Dabie Mountains.Previous studies have suggested that genetic differentiation and geographical isolation exist between ...Hyla tsinlingensis(Hu et al.,1966)is endemic to China,and is widely distributed in the Qinling and Dabie Mountains.Previous studies have suggested that genetic differentiation and geographical isolation exist between the Qinling Mountains population and Dabie Mountains population of H.tsinlingensis,and that the Dabie Mountains population is a cryptic species.Several Hyla specimens were collected from the Dabie Mountains of western Anhui Province,China during herpetological surveys from 2022‒2024;these specimens belonged to a species previously identified as H.tsinlingensis.Herein,we utilized phylogenetic analyses,morphological comparisons,and advertisement call comparisons,revealing significant differences from those of other known congeners;thus,we describe them as a new species.The discovery of this species implies that there are currently 18 identified species in the genus Hyla,7 of which are found in China.展开更多
Objectives:Suicidal ideation(SI)among university students is a growing concern,influenced by anxiety,depression,and bullying.However,family closeness and peer support may act as protective factors,reducing the risk of...Objectives:Suicidal ideation(SI)among university students is a growing concern,influenced by anxiety,depression,and bullying.However,family closeness and peer support may act as protective factors,reducing the risk of SI.Therefore,this study aims to investigate the key factors influencing SI among university students,focusing on the effects of anxiety,depression,and bullying,along with the roles of family closeness and peer support.The research also explores the interactions and mechanisms between these variables.Methods:A sample of 318 university students was surveyed,evaluating six main factors:anxiety,depression,bullying,family closeness,peer support,and SI.Using the Structural Equation Modeling(SEM)and Artificial Neural Networks(ANN)approach,both compensatory and non-compensatory relationships were examined.Results:Anxiety,depression,and bullying significantly contribute to SI,with depression mediating the link between anxiety,bullying,and SI.Additionally,family closeness moderates the effects of anxiety and bullying on SI,while peer supportmoderates the effects of depression and bullying.Themultilayer perceptron analysis identifies peer support as the most influential predictor,followed by bullying,family closeness,depression,and anxiety.Conclusion:The study identifies anxiety,depression,and bullying as key factors influencing suicidal ideation(SI)among university students.Family closeness and peer support act as protective factors,moderating the effects of these variables on SI.展开更多
BACKGROUND The Zhejiang University(ZJU)index has been demonstrated to have notable value in predicting metabolic dysfunction-associated steatotic liver disease(MASLD)within Chinese populations.However,the correlation ...BACKGROUND The Zhejiang University(ZJU)index has been demonstrated to have notable value in predicting metabolic dysfunction-associated steatotic liver disease(MASLD)within Chinese populations.However,the correlation between the ZJU index and MASLD in type 2 diabetes mellitus(T2DM)patients remains to be elucidated.AIM To investigate the association between the ZJU index and MASLD among patients with T2DM.METHODS This cross-sectional study was conducted on hospitalised patients diagnosed with T2DM.Anthropometric measurements,laboratory data,and ultrasound results were initially collected from all patients.The ZJU index was subsequently calculated.Regression analysis was then used to explore risk factors affecting MASLD,and the optimal ZJU index cut-off value for diagnosing MASLD was determined using restricted cubic spline analysis.Finally,a new model for predicting MASLD in T2DM patients based on the ZJU index was constructed.This model was based on the risk factors identified by regression analysis,and the area under curve values were calculated.The validity and reliability of the models were then compared with each other.RESULTS A total of 688 patients with T2DM were included in this study.A significant positive correlation was identified between the ZJU index and the development of MASLD.Furthermore,the results of the restricted cubic spline analysis showed a non-linear association between ZJU index and MASLD.The ZJU value of 38.87 was identified as the key threshold for diagnosing MASLD.The new predictive model,which was developed by regression analysis,demonstrated a higher diagnostic value for MASLD and exhibited good accuracy in comparison with metabolic indices alone(area under curve=0.76,95%confidence interval:0.72-0.80).CONCLUSION The ZJU index has been shown to be linked to the risk of developing MASLD,and the new model constructed has been shown to possess good predictive value.展开更多
Anhui Province is a major agricultural province in eastern China,and the development of rural economy plays an important role in improving the overall economic level of the province.In recent years,the extensive use o...Anhui Province is a major agricultural province in eastern China,and the development of rural economy plays an important role in improving the overall economic level of the province.In recent years,the extensive use of digital technologies and ongoing financial innovations have contributed to the rapid growth of digital inclusive finance in rural areas of Anhui,significantly reducing the lack of financial services in these regions.The main objective of this paper is to explore in depth how digital inclusive finance impacts the rural economy of Anhui Province and to provide practical policy recommendations based on these findings.展开更多
Dear Editor,The true frogs classified under the genus Rana, with widespread distribution in Eurasia and North America,constitute a varied and intricate group (Yuan et al., 2016;Chen et al., 2022). In total, 52 species...Dear Editor,The true frogs classified under the genus Rana, with widespread distribution in Eurasia and North America,constitute a varied and intricate group (Yuan et al., 2016;Chen et al., 2022). In total, 52 species within this genus have been documented (IUCN, 2024), with 28 of those species found in China (Amphibia China, 2024).展开更多
In this paper,a novel method for investigating the particle-crushing behavior of breeding particles in a fusion blanket is proposed.The fractal theory and Weibull distribution are combined to establish a theoretical m...In this paper,a novel method for investigating the particle-crushing behavior of breeding particles in a fusion blanket is proposed.The fractal theory and Weibull distribution are combined to establish a theoretical model,and its validity was verified using a simple impact test.A crushable discrete element method(DEM)framework is built based on the previously established theoretical model.The tensile strength,which considers the fractal theory,size effect,and Weibull variation,was assigned to each generated particle.The assigned strength is then used for crush detection by comparing it with its maximum tensile stress.Mass conservation is ensured by inserting a series of sub-particles whose total mass was equal to the quality loss.Based on the crushable DEM framework,a numerical simulation of the crushing behavior of a pebble bed with hollow cylindrical geometry under a uniaxial compression test was performed.The results of this investigation showed that the particle withstands the external load by contact and sliding at the beginning of the compression process,and the results confirmed that crushing can be considered an important method of resisting the increasing external load.A relatively regular particle arrangement aids in resisting the load and reduces the occurrence of particle crushing.However,a limit exists to the promotion of resistance.When the strain increases beyond this limit,the distribution of the crushing position tends to be isotropic over the entire pebble bed.The theoretical model and crushable DEM framework provide a new method for exploring the pebble bed in a fusion reactor,considering particle crushing.展开更多
Images taken in dim environments frequently exhibit issues like insufficient brightness,noise,color shifts,and loss of detail.These problems pose significant challenges to dark image enhancement tasks.Current approach...Images taken in dim environments frequently exhibit issues like insufficient brightness,noise,color shifts,and loss of detail.These problems pose significant challenges to dark image enhancement tasks.Current approaches,while effective in global illumination modeling,often struggle to simultaneously suppress noise and preserve structural details,especially under heterogeneous lighting.Furthermore,misalignment between luminance and color channels introduces additional challenges to accurate enhancement.In response to the aforementioned difficulties,we introduce a single-stage framework,M2ATNet,using the multi-scale multi-attention and Transformer architecture.First,to address the problems of texture blurring and residual noise,we design a multi-scale multi-attention denoising module(MMAD),which is applied separately to the luminance and color channels to enhance the structural and texture modeling capabilities.Secondly,to solve the non-alignment problem of the luminance and color channels,we introduce the multi-channel feature fusion Transformer(CFFT)module,which effectively recovers the dark details and corrects the color shifts through cross-channel alignment and deep feature interaction.To guide the model to learn more stably and efficiently,we also fuse multiple types of loss functions to form a hybrid loss term.We extensively evaluate the proposed method on various standard datasets,including LOL-v1,LOL-v2,DICM,LIME,and NPE.Evaluation in terms of numerical metrics and visual quality demonstrate that M2ATNet consistently outperforms existing advanced approaches.Ablation studies further confirm the critical roles played by the MMAD and CFFT modules to detail preservation and visual fidelity under challenging illumination-deficient environments.展开更多
Vitamin D deficiency(VDD)represents a significant nutritional concern among children and adolescents.The estimated prevalence of VDD in China is 46.8%in this population^([1]).VDD during childhood and adolescence has b...Vitamin D deficiency(VDD)represents a significant nutritional concern among children and adolescents.The estimated prevalence of VDD in China is 46.8%in this population^([1]).VDD during childhood and adolescence has been associated with the onset of various conditions,including acute respiratory infections,asthma,atopic dermatitis,and food allergies^([2]).Multiple factors,including age,sun exposure,adiposity,and genetics,influence vitamin D levels^([2,3]).Increasing attention has been directed toward understanding the environmental determinants that may influence vitamin D status.Given the potential of metallic pollutants to disrupt endocrine function and their ubiquity in the environment,investigating the effects of metal exposure on human vitamin D status,particularly in vulnerable populations,is imperative.展开更多
Flash Joule heating(FJH),as a high-efficiency and low-energy consumption technology for advanced materials synthesis,has shown significant potential in the synthesis of graphene and other functional carbon materials.B...Flash Joule heating(FJH),as a high-efficiency and low-energy consumption technology for advanced materials synthesis,has shown significant potential in the synthesis of graphene and other functional carbon materials.Based on the Joule effect,the solid carbon sources can be rapidly heated to ultra-high temperatures(>3000 K)through instantaneous high-energy current pulses during FJH,thus driving the rapid rearrangement and graphitization of carbon atoms.This technology demonstrates numerous advantages,such as solvent-and catalyst-free features,high energy conversion efficiency,and a short process cycle.In this review,we have systematically summarized the technology principle and equipment design for FJH,as well as its raw materials selection and pretreatment strategies.The research progress in the FJH synthesis of flash graphene,carbon nanotubes,graphene fibers,and anode hard carbon,as well as its by-products,is also presented.FJH can precisely optimize the microstructures of carbon materials(e.g.,interlayer spacing of turbostratic graphene,defect concentration,and heteroatom doping)by regulating its operation parameters like flash voltage and flash time,thereby enhancing their performances in various applications,such as composite reinforcement,metal-ion battery electrodes,supercapacitors,and electrocatalysts.However,this technology is still challenged by low process yield,macroscopic material uniformity,and green power supply system construction.More research efforts are also required to promote the transition of FJH from laboratory to industrial-scale applications,thus providing innovative solutions for advanced carbon materials manufacturing and waste management toward carbon neutrality.展开更多
UV-B application enhances the aroma quality of oolong tea;however,the underlying regulatory mechanism remains unclear.This study investigates the regulatory role of UV-B in the biosynthesis of a-farnesene,an important...UV-B application enhances the aroma quality of oolong tea;however,the underlying regulatory mechanism remains unclear.This study investigates the regulatory role of UV-B in the biosynthesis of a-farnesene,an important floral and fruity characteristic aroma.UV-B treatment significantly improved the aroma quality of‘Foshou’and‘Yuquan’oolong teas,increasing a-farnesene levels by 1.8-and 1.4-fold,respectively.The a-farnesene synthase(CsAFS),ELONGATED HYPOCOTYL 5(CsHY5),and myelocytomatosis protein 2(CsMYC2)exhibited a highly correlated expression pattern closely associated with a-farnesene accumulation.Single-factor treatment revealed that CsAFS expression was induced by both UV-B and mechanical wounding,with CsHY5 predominantly responding to UV-B radiation,while CsMYC2 primarily responded to tumbling-induced mechanical wounding signal.Transient suppression of CsHY5 in tea leaves reduced the expression of both CsAFS and CsMYC2 whereas CsMYC2 suppression decreased CsAFS expression.G-box motifs were identified in promoters of CsMYC2 and CsAFS,and the dual-luciferase reporter assay(LUC)and electrophoretic mobility shift assays(EMSA)demonstrated direct binding functions of CsHY5 to CsAFS and CsMYC2 promoters,as well as CsMYC2 to the CsAFS promoter.Based on sensory evaluation,odourant quantification,gene expression,and molecular functional analysis,we propose that UV-B radiation and tumbling-induced wounding signals synergistically regulate a-farnesene biosynthesis through a coordinated interaction of CsHY5 and CsMYC2 during oolong tea processing.These findings improve our understanding of flavour formation during oolong tea production and also provide novel insights into artificial light application in tea manufacturing.展开更多
TiB_(2)coatings can significantly enhance the high-temperature oxidation resistance of molybdenum,which would broaden the application range of molybdenum and alloys thereof.However,traditional methods for preparing Ti...TiB_(2)coatings can significantly enhance the high-temperature oxidation resistance of molybdenum,which would broaden the application range of molybdenum and alloys thereof.However,traditional methods for preparing TiB_(2)coatings have disadvantages such as high equipment costs,complicated processes,and highly toxic gas emissions.This paper proposes an environmentally friendly method,which requires inexpensive equipment and simple processing,for preparing TiB_(2)coating on molybdenum via electrophoretic deposition within Na3AlF6-based molten salts.The produced TiB_(2)layer had an approximate thickness of 60μm and exhibited high density,outstanding hardness(38.2 GPa)and robust adhesion strength(51 N).Additionally,high-temperature oxidation experiments revealed that,at900℃,the TiB_(2)coating provided effective protection to the molybdenum substrate against oxidation for 3 h.This result indicates that the TiB_(2)coating prepared on molybdenum using molten salt electrophoretic deposition possesses good high-temperature oxidation resistance.展开更多
Spontaneous recovery frequently proves maladaptive or insufficient because the plasticity of the injured adult mammalian central nervous system is limited.This limited plasticity serves as a primary barrier to functio...Spontaneous recovery frequently proves maladaptive or insufficient because the plasticity of the injured adult mammalian central nervous system is limited.This limited plasticity serves as a primary barrier to functional recovery after brain injury.Neuromodulation technologies represent one of the fastest-growing fields in medicine.These techniques utilize electricity,magnetism,sound,and light to restore or optimize brain functions by promoting reorganization or long-term changes that support functional recovery in patients with brain injury.Therefore,this review aims to provide a comprehensive overview of the effects and underlying mechanisms of neuromodulation technologies in supporting motor function recovery after brain injury.Many of these technologies are widely used in clinical practice and show significant improvements in motor function across various types of brain injury.However,studies report negative findings,potentially due to variations in stimulation protocols,differences in observation periods,and the severity of functional impairments among participants across different clinical trials.Additionally,we observed that different neuromodulation techniques share remarkably similar mechanisms,including promoting neuroplasticity,enhancing neurotrophic factor release,improving cerebral blood flow,suppressing neuroinflammation,and providing neuroprotection.Finally,considering the advantages and disadvantages of various neuromodulation techniques,we propose that future development should focus on closed-loop neural circuit stimulation,personalized treatment,interdisciplinary collaboration,and precision stimulation.展开更多
Flexible electronics face critical challenges in achieving monolithic three-dimensional(3D)integration,including material compatibility,structural stability,and scalable fabrication methods.Inspired by the tactile sen...Flexible electronics face critical challenges in achieving monolithic three-dimensional(3D)integration,including material compatibility,structural stability,and scalable fabrication methods.Inspired by the tactile sensing mechanism of the human skin,we have developed a flexible monolithic 3D-integrated tactile sensing system based on a holey MXene paste,where each vertical one-body unit simultaneously functions as a microsupercapacitor and pressure sensor.The in-plane mesopores of MXene significantly improve ion accessibility,mitigate the self-stacking of nanosheets,and allow the holey MXene to multifunctionally act as a sensing material,an active electrode,and a conductive interconnect,thus drastically reducing the interface mismatch and enhancing the mechanical robustness.Furthermore,we fabricate a large-scale device using a blade-coating and stamping method,which demonstrates excellent mechanical flexibility,low-power consumption,rapid response,and stable long-term operation.As a proof-of-concept application,we integrate our sensing array into a smart access control system,leveraging deep learning to accurately identify users based on their unique pressing behaviors.This study provides a promising approach for designing highly integrated,intelligent,and flexible electronic systems for advanced human-computer interactions and personalized electronics.展开更多
Optimizing the microchannel design of the next generation of chips requires an understanding of the in situ property evolution of the chip-based materials under fast cooling.This work overcomes the conventional relian...Optimizing the microchannel design of the next generation of chips requires an understanding of the in situ property evolution of the chip-based materials under fast cooling.This work overcomes the conventional reliance on reheating data of melt-quenched glasses by demonstrating direct observations of glass transition on cooling curves utilizing the most advanced fast differential scanning calorimetry.By leveraging an MEMS chip sensor that allows for rapid heat extraction from microgram-sized samples to a purged gas coolant,the device is able to reach ultra-fast cooling rates of up to 40,000 K·s^(−1).Four thermal regions are identified by examining the cooling behaviors of two metallic glasses.This is because the actual rate of the specimen can differ from the programmed rate,especially at high set rate when the actual rate decreases before the glass transition is completed.We define the operational window for reliable cooling curve analysis,build models with empirical and theoretical analyses to determine the maximum feasible cooling rate,and demonstrate how optimizing sample mass and environment temperature broaden this window.The method avoids deceptive structural relaxation effects verified by fictivetemperature analysis and permits the capture of full glass transition during cooling.展开更多
In 2021,approximately 537 million people suffered from diabetes mellitus(DM)globally,and this figure will increase to approximately 783 million within the next quarter-century.The increasing burden of DM is a pressing...In 2021,approximately 537 million people suffered from diabetes mellitus(DM)globally,and this figure will increase to approximately 783 million within the next quarter-century.The increasing burden of DM is a pressing global public health issue.Therefore,the early identification of high-risk groups and implementation of effective intervention measures is imperative.展开更多
BACKGROUND Early screening,preoperative staging,and diagnosis of lymph node metastasis are crucial for improving the prognosis of gastric cancer(GC).AIM To evaluate the diagnostic value of combined multidetector compu...BACKGROUND Early screening,preoperative staging,and diagnosis of lymph node metastasis are crucial for improving the prognosis of gastric cancer(GC).AIM To evaluate the diagnostic value of combined multidetector computed tomography(MDCT)and gastrointestinal endoscopy for GC screening,preoperative staging,and lymph node metastasis detection,thereby providing a reference for clinical diagnosis and treatment.METHODS In this retrospective study clinical and imaging data of 134 patients with suspected GC who were admitted between January 2023 and October 2024 were initially reviewed.According to the inclusion and exclusion criteria,102 patients were finally enrolled in the analysis.All enrolled patients had undergone both MDCT and gastrointestinal endoscopy examinations prior to surgical intervention.Preoperative clinical staging and lymph node metastasis findings were compared with pathological results.RESULTS The combined use of MDCT and gastrointestinal endoscopy demonstrated a sensitivity of 98.53%,specificity of 97.06%,accuracy of 98.04%,positive predictive value of 98.53%,and negative predictive value of 97.06%for diagnosing GC.These factors were all significantly higher than those of MDCT or endoscopy alone(P<0.05).The accuracy rates of the combined approach for detecting clinical T and N stages were 97.06%and 92.65%,respectively,outperforming MDCT alone(86.76% and 79.41%)and endoscopy alone(85.29% and 70.59%)(P<0.05).Among 68 patients with confirmed GC,50(73.53%)were pathologically diagnosed with lymph node metastasis.The accuracy for detecting lymph node metastasis was 66.00%with endoscopy,76.00%with MDCT,and 92.00% with the combined approach,all with statistically significant differences(P<0.05).CONCLUSION The combined application of MDCT and gastrointestinal endoscopy enhanced diagnostic accuracy for GC,provided greater consistency in preoperative staging,and improved the detection of lymph node metastasis,thereby demonstrating significant clinical utility.展开更多
Along with decrease of fine particulate matter(PM_(2.5))concentration in recent years in China,secondary species become increasingly important.This work focuses on characterizing secondary components,and a few importa...Along with decrease of fine particulate matter(PM_(2.5))concentration in recent years in China,secondary species become increasingly important.This work focuses on characterizing secondary components,and a few important groups of organics including organic nitrogen(ON),organonitrates(OrgN),organosulfates(OS)and polycyclic aromatic hydrocarbons(PAHs),via online measurement of submicron aerosols(PM_(1))in Nanjing,China,during 2022 summer.The average PM_(1) concentration was 15.39μg/m^(3),dominated by secondary components(69.1%),which were even more important at higher PM_(1) levels.The primary organic aerosols(POA)were from traffic,industry and cooking;the two secondary OA factors were both closely linked with photochemistry,with one(OOA1)being relatively fresh and important in early afternoon and another(OOA2)being aged and important in late afternoon.Sulfate formation was also governed by photochemistry but resembled that of OOA2 not OOA1;nitrate formation was associated strongly with heterogeneous hydrolysis and thermodynamic equilibrium.Results also reveal a possible photochemical reaction channel from POA to OOA1,then to OOA2.Case studies show that formations of secondary components responded differently to different weather conditions and governed summer PM_(1) pollution.The average ON,OrgN,OS and PAHs concentrations were determined to be 122.8,84.4,45.6 and 3.3 ng/m^(3),respectively.ON was dominated by primary sources(53.8%).OrgN varied similarly to nitrate.OS formation was linked with aqueous-phase reactions,which were insignificant therefore its level was low.PAHs was mainly from traffic,and photochemical oxidation might be its important sink during afternoon.展开更多
We conducted a field campaign to investigate the chemical composition,sources,and light absorption of submicron aerosols(PM_(1))from early 2022 in Nanjing,China.The average concentration of PM_(1) was 31μg m^(−3),org...We conducted a field campaign to investigate the chemical composition,sources,and light absorption of submicron aerosols(PM_(1))from early 2022 in Nanjing,China.The average concentration of PM_(1) was 31μg m^(−3),organics(33%)constituted the largest fraction,followed by nitrate(30%),sulfate(18%),ammonium(15%),chloride(3%),and rBC(2%).Four organic aerosol(OA)subcomponents were identified,including two primary OA(POA)and two secondary OA(SOA).The less-oxidized SOA(LO-OOA)contributes the most to the total OA mass(59%).LO-OOA is tightly correlated with the tracer ion C_(2)H_(4)O_(2)^(+)from levoglucosan,and another aged biomass-burning derived species,K_(3)SO_(4)^(+),suggesting it was likely influenced by aged biomass-burning OA.Our study also revealed that fireworks during the Spring Festival have a detrimental impact on air quality,contributing to secondary formation and accumulation under static winter meteorological conditions,prolonging the pollution duration.Also,LO-OOA was found to have the strongest light-absorbing ability.Our results highlight that the light absorption of LO-OOA can mainly be attributed to the C_(x)H_(y)N^(+) family,increased with the double-bond equivalent value.The more-oxidized SOA(MO-OOA)exhibited a negligible light absorption and was strongly correlated with daytime photochemical processes,implying a light-bleaching effect.This study enhances our understanding of the regional contribution of biomass combustion and fireworks to PM_(1) pollution in Nanjing,a typical megacity in the Yangtze River Delta region,during winter,aiding in the development of strategies for long-term air quality improvement in the region.展开更多
文摘The construction of local applied colleges and universities has always been an important part of the construction and development of higher education in China. As a representative local applied undergraduate college in Anhui Province, West Anhui University has actively explored and practiced the construction of "second classroom" education system since September 2017, which has played a positive role in promoting the school teaching reform and the all-round development of collaborative education, but there are some problems in the practice. Using the big data of "Second Classroom" activities in West Anhui University, this paper analyzes the data of "Second Classroom" activities of students of grade 2020 and 2021 by using data mining technology. From the analysis results, it can be seen that there are some problems in "Second Classroom" activities in schools, such as unclear local characteristics, uneven curriculum distribution, uneven curriculum quality, and different participation in different types of activities, etc., and some corresponding suggestions are put forward in order to build a scientific system design, management system and curriculum arrangement.
基金Sponsored by National Undergraduate Innovation Training Program of Anhui Xinhua University(202412216001)Provincial-level Undergraduate Innovation Training Program of Anhui Xinhua University(S202312216041)+1 种基金Natural Science Key Research Program for Colleges and Universities in Anhui Province(2023AH051816)Anhui General Teaching Research Project(2022jyxm665).
文摘The investigation and analysis of woody plants on the campus of Anhui Xinhua University reveals the presence of 103 species distributed across 43 families and 78 genera.Notably,depauperate families and monotypic genera are found to be the most numerous.Among the families,Rosaceae is identified as the most diverse,encompassing a total of 21 species,while Prunus is found to contain the highest number of species,totaling 5.The geographic component of the plant flora is intricate and encompasses a wide range of distribution types,with a predominance of both tropic and temperate plants.
基金The Comprehensive Monitoring Station for National Ecological Quality in the Dabie Mountains(Forest)Ecological Monitoring for the Years 2024‒2025(ZF2024-18-1376)。
文摘Hyla tsinlingensis(Hu et al.,1966)is endemic to China,and is widely distributed in the Qinling and Dabie Mountains.Previous studies have suggested that genetic differentiation and geographical isolation exist between the Qinling Mountains population and Dabie Mountains population of H.tsinlingensis,and that the Dabie Mountains population is a cryptic species.Several Hyla specimens were collected from the Dabie Mountains of western Anhui Province,China during herpetological surveys from 2022‒2024;these specimens belonged to a species previously identified as H.tsinlingensis.Herein,we utilized phylogenetic analyses,morphological comparisons,and advertisement call comparisons,revealing significant differences from those of other known congeners;thus,we describe them as a new species.The discovery of this species implies that there are currently 18 identified species in the genus Hyla,7 of which are found in China.
文摘Objectives:Suicidal ideation(SI)among university students is a growing concern,influenced by anxiety,depression,and bullying.However,family closeness and peer support may act as protective factors,reducing the risk of SI.Therefore,this study aims to investigate the key factors influencing SI among university students,focusing on the effects of anxiety,depression,and bullying,along with the roles of family closeness and peer support.The research also explores the interactions and mechanisms between these variables.Methods:A sample of 318 university students was surveyed,evaluating six main factors:anxiety,depression,bullying,family closeness,peer support,and SI.Using the Structural Equation Modeling(SEM)and Artificial Neural Networks(ANN)approach,both compensatory and non-compensatory relationships were examined.Results:Anxiety,depression,and bullying significantly contribute to SI,with depression mediating the link between anxiety,bullying,and SI.Additionally,family closeness moderates the effects of anxiety and bullying on SI,while peer supportmoderates the effects of depression and bullying.Themultilayer perceptron analysis identifies peer support as the most influential predictor,followed by bullying,family closeness,depression,and anxiety.Conclusion:The study identifies anxiety,depression,and bullying as key factors influencing suicidal ideation(SI)among university students.Family closeness and peer support act as protective factors,moderating the effects of these variables on SI.
基金Supported by Health Research Program of Anhui,No.AHWJ2023BAc10010Clinical and Translational Research Project of Anhui Province,No.202427b10020078。
文摘BACKGROUND The Zhejiang University(ZJU)index has been demonstrated to have notable value in predicting metabolic dysfunction-associated steatotic liver disease(MASLD)within Chinese populations.However,the correlation between the ZJU index and MASLD in type 2 diabetes mellitus(T2DM)patients remains to be elucidated.AIM To investigate the association between the ZJU index and MASLD among patients with T2DM.METHODS This cross-sectional study was conducted on hospitalised patients diagnosed with T2DM.Anthropometric measurements,laboratory data,and ultrasound results were initially collected from all patients.The ZJU index was subsequently calculated.Regression analysis was then used to explore risk factors affecting MASLD,and the optimal ZJU index cut-off value for diagnosing MASLD was determined using restricted cubic spline analysis.Finally,a new model for predicting MASLD in T2DM patients based on the ZJU index was constructed.This model was based on the risk factors identified by regression analysis,and the area under curve values were calculated.The validity and reliability of the models were then compared with each other.RESULTS A total of 688 patients with T2DM were included in this study.A significant positive correlation was identified between the ZJU index and the development of MASLD.Furthermore,the results of the restricted cubic spline analysis showed a non-linear association between ZJU index and MASLD.The ZJU value of 38.87 was identified as the key threshold for diagnosing MASLD.The new predictive model,which was developed by regression analysis,demonstrated a higher diagnostic value for MASLD and exhibited good accuracy in comparison with metabolic indices alone(area under curve=0.76,95%confidence interval:0.72-0.80).CONCLUSION The ZJU index has been shown to be linked to the risk of developing MASLD,and the new model constructed has been shown to possess good predictive value.
文摘Anhui Province is a major agricultural province in eastern China,and the development of rural economy plays an important role in improving the overall economic level of the province.In recent years,the extensive use of digital technologies and ongoing financial innovations have contributed to the rapid growth of digital inclusive finance in rural areas of Anhui,significantly reducing the lack of financial services in these regions.The main objective of this paper is to explore in depth how digital inclusive finance impacts the rural economy of Anhui Province and to provide practical policy recommendations based on these findings.
基金supported by the National Natural Science Foundation of China (No.31970499 to Liuwang NIE)。
文摘Dear Editor,The true frogs classified under the genus Rana, with widespread distribution in Eurasia and North America,constitute a varied and intricate group (Yuan et al., 2016;Chen et al., 2022). In total, 52 species within this genus have been documented (IUCN, 2024), with 28 of those species found in China (Amphibia China, 2024).
基金supported by Anhui Provincial Natural Science Foundation(2408085QA030)Natural Science Research Project of Anhui Educational Committee,China(2022AH050825)+3 种基金Medical Special Cultivation Project of Anhui University of Science and Technology(YZ2023H2C008)the Excellent Research and Innovation Team of Anhui Province,China(2022AH010052)the Scientific Research Foundation for High-level Talents of Anhui University of Science and Technology,China(2021yjrc51)Collaborative Innovation Program of Hefei Science Center,CAS,China(2019HSC-CIP006).
文摘In this paper,a novel method for investigating the particle-crushing behavior of breeding particles in a fusion blanket is proposed.The fractal theory and Weibull distribution are combined to establish a theoretical model,and its validity was verified using a simple impact test.A crushable discrete element method(DEM)framework is built based on the previously established theoretical model.The tensile strength,which considers the fractal theory,size effect,and Weibull variation,was assigned to each generated particle.The assigned strength is then used for crush detection by comparing it with its maximum tensile stress.Mass conservation is ensured by inserting a series of sub-particles whose total mass was equal to the quality loss.Based on the crushable DEM framework,a numerical simulation of the crushing behavior of a pebble bed with hollow cylindrical geometry under a uniaxial compression test was performed.The results of this investigation showed that the particle withstands the external load by contact and sliding at the beginning of the compression process,and the results confirmed that crushing can be considered an important method of resisting the increasing external load.A relatively regular particle arrangement aids in resisting the load and reduces the occurrence of particle crushing.However,a limit exists to the promotion of resistance.When the strain increases beyond this limit,the distribution of the crushing position tends to be isotropic over the entire pebble bed.The theoretical model and crushable DEM framework provide a new method for exploring the pebble bed in a fusion reactor,considering particle crushing.
基金funded by the National Natural Science Foundation of China,grant numbers 52374156 and 62476005。
文摘Images taken in dim environments frequently exhibit issues like insufficient brightness,noise,color shifts,and loss of detail.These problems pose significant challenges to dark image enhancement tasks.Current approaches,while effective in global illumination modeling,often struggle to simultaneously suppress noise and preserve structural details,especially under heterogeneous lighting.Furthermore,misalignment between luminance and color channels introduces additional challenges to accurate enhancement.In response to the aforementioned difficulties,we introduce a single-stage framework,M2ATNet,using the multi-scale multi-attention and Transformer architecture.First,to address the problems of texture blurring and residual noise,we design a multi-scale multi-attention denoising module(MMAD),which is applied separately to the luminance and color channels to enhance the structural and texture modeling capabilities.Secondly,to solve the non-alignment problem of the luminance and color channels,we introduce the multi-channel feature fusion Transformer(CFFT)module,which effectively recovers the dark details and corrects the color shifts through cross-channel alignment and deep feature interaction.To guide the model to learn more stably and efficiently,we also fuse multiple types of loss functions to form a hybrid loss term.We extensively evaluate the proposed method on various standard datasets,including LOL-v1,LOL-v2,DICM,LIME,and NPE.Evaluation in terms of numerical metrics and visual quality demonstrate that M2ATNet consistently outperforms existing advanced approaches.Ablation studies further confirm the critical roles played by the MMAD and CFFT modules to detail preservation and visual fidelity under challenging illumination-deficient environments.
基金supported by grants from the National Natural Science Foundation of China(G.F.Wang,grant number 82204071)(P.Y.Su,grant numbers 81874268 and 82473655)the Research Funds of the Center for Big Data and Population Health of IHM(P.Y.Su,No.JKS2023016)Anhui Provincial Health Commission Scientific Research Project(Y.Zhou,No.AHWJ2023A30027)。
文摘Vitamin D deficiency(VDD)represents a significant nutritional concern among children and adolescents.The estimated prevalence of VDD in China is 46.8%in this population^([1]).VDD during childhood and adolescence has been associated with the onset of various conditions,including acute respiratory infections,asthma,atopic dermatitis,and food allergies^([2]).Multiple factors,including age,sun exposure,adiposity,and genetics,influence vitamin D levels^([2,3]).Increasing attention has been directed toward understanding the environmental determinants that may influence vitamin D status.Given the potential of metallic pollutants to disrupt endocrine function and their ubiquity in the environment,investigating the effects of metal exposure on human vitamin D status,particularly in vulnerable populations,is imperative.
基金supported by the National Natural Science Foundation of China(52276196)the Foundation of State Key Laboratory of Coal Combustion(FSKLCCA2508)the High-level Talent Foundation of Anhui Agricultural University(rc412307).
文摘Flash Joule heating(FJH),as a high-efficiency and low-energy consumption technology for advanced materials synthesis,has shown significant potential in the synthesis of graphene and other functional carbon materials.Based on the Joule effect,the solid carbon sources can be rapidly heated to ultra-high temperatures(>3000 K)through instantaneous high-energy current pulses during FJH,thus driving the rapid rearrangement and graphitization of carbon atoms.This technology demonstrates numerous advantages,such as solvent-and catalyst-free features,high energy conversion efficiency,and a short process cycle.In this review,we have systematically summarized the technology principle and equipment design for FJH,as well as its raw materials selection and pretreatment strategies.The research progress in the FJH synthesis of flash graphene,carbon nanotubes,graphene fibers,and anode hard carbon,as well as its by-products,is also presented.FJH can precisely optimize the microstructures of carbon materials(e.g.,interlayer spacing of turbostratic graphene,defect concentration,and heteroatom doping)by regulating its operation parameters like flash voltage and flash time,thereby enhancing their performances in various applications,such as composite reinforcement,metal-ion battery electrodes,supercapacitors,and electrocatalysts.However,this technology is still challenged by low process yield,macroscopic material uniformity,and green power supply system construction.More research efforts are also required to promote the transition of FJH from laboratory to industrial-scale applications,thus providing innovative solutions for advanced carbon materials manufacturing and waste management toward carbon neutrality.
基金supported by the National Natural Science Foundation of China(Grant No.32072623)the National Key Research and Development Program of China(Grant No.2021YFD1601103).
文摘UV-B application enhances the aroma quality of oolong tea;however,the underlying regulatory mechanism remains unclear.This study investigates the regulatory role of UV-B in the biosynthesis of a-farnesene,an important floral and fruity characteristic aroma.UV-B treatment significantly improved the aroma quality of‘Foshou’and‘Yuquan’oolong teas,increasing a-farnesene levels by 1.8-and 1.4-fold,respectively.The a-farnesene synthase(CsAFS),ELONGATED HYPOCOTYL 5(CsHY5),and myelocytomatosis protein 2(CsMYC2)exhibited a highly correlated expression pattern closely associated with a-farnesene accumulation.Single-factor treatment revealed that CsAFS expression was induced by both UV-B and mechanical wounding,with CsHY5 predominantly responding to UV-B radiation,while CsMYC2 primarily responded to tumbling-induced mechanical wounding signal.Transient suppression of CsHY5 in tea leaves reduced the expression of both CsAFS and CsMYC2 whereas CsMYC2 suppression decreased CsAFS expression.G-box motifs were identified in promoters of CsMYC2 and CsAFS,and the dual-luciferase reporter assay(LUC)and electrophoretic mobility shift assays(EMSA)demonstrated direct binding functions of CsHY5 to CsAFS and CsMYC2 promoters,as well as CsMYC2 to the CsAFS promoter.Based on sensory evaluation,odourant quantification,gene expression,and molecular functional analysis,we propose that UV-B radiation and tumbling-induced wounding signals synergistically regulate a-farnesene biosynthesis through a coordinated interaction of CsHY5 and CsMYC2 during oolong tea processing.These findings improve our understanding of flavour formation during oolong tea production and also provide novel insights into artificial light application in tea manufacturing.
基金supported by the Original Exploratory Program of the National Natural Science Foundation of China(No.52450012)。
文摘TiB_(2)coatings can significantly enhance the high-temperature oxidation resistance of molybdenum,which would broaden the application range of molybdenum and alloys thereof.However,traditional methods for preparing TiB_(2)coatings have disadvantages such as high equipment costs,complicated processes,and highly toxic gas emissions.This paper proposes an environmentally friendly method,which requires inexpensive equipment and simple processing,for preparing TiB_(2)coating on molybdenum via electrophoretic deposition within Na3AlF6-based molten salts.The produced TiB_(2)layer had an approximate thickness of 60μm and exhibited high density,outstanding hardness(38.2 GPa)and robust adhesion strength(51 N).Additionally,high-temperature oxidation experiments revealed that,at900℃,the TiB_(2)coating provided effective protection to the molybdenum substrate against oxidation for 3 h.This result indicates that the TiB_(2)coating prepared on molybdenum using molten salt electrophoretic deposition possesses good high-temperature oxidation resistance.
基金supported by the National Natural Science Foundation of China,No.82371399(to YY)the Natural Science Foundation of Jiangsu Province,No.BK20221206(to YY)+1 种基金the Young Elite Scientists Sponsorship Program of Jiangsu Province,No.TJ-2022-028(to YY)the Scientific Research Program of Wuxi Health Commission,No.Z202302(to LY)。
文摘Spontaneous recovery frequently proves maladaptive or insufficient because the plasticity of the injured adult mammalian central nervous system is limited.This limited plasticity serves as a primary barrier to functional recovery after brain injury.Neuromodulation technologies represent one of the fastest-growing fields in medicine.These techniques utilize electricity,magnetism,sound,and light to restore or optimize brain functions by promoting reorganization or long-term changes that support functional recovery in patients with brain injury.Therefore,this review aims to provide a comprehensive overview of the effects and underlying mechanisms of neuromodulation technologies in supporting motor function recovery after brain injury.Many of these technologies are widely used in clinical practice and show significant improvements in motor function across various types of brain injury.However,studies report negative findings,potentially due to variations in stimulation protocols,differences in observation periods,and the severity of functional impairments among participants across different clinical trials.Additionally,we observed that different neuromodulation techniques share remarkably similar mechanisms,including promoting neuroplasticity,enhancing neurotrophic factor release,improving cerebral blood flow,suppressing neuroinflammation,and providing neuroprotection.Finally,considering the advantages and disadvantages of various neuromodulation techniques,we propose that future development should focus on closed-loop neural circuit stimulation,personalized treatment,interdisciplinary collaboration,and precision stimulation.
基金supported by the National Natural Science Foundation of China(52272177,12204010)the Foundation for the Introduction of High-Level Talents of Anhui University(S020118002/097)+1 种基金the University Synergy Innovation Program of Anhui Province(GXXT-2023-066)the Scientific Research Project of Anhui Provincial Higher Education Institution(2023AH040008)。
文摘Flexible electronics face critical challenges in achieving monolithic three-dimensional(3D)integration,including material compatibility,structural stability,and scalable fabrication methods.Inspired by the tactile sensing mechanism of the human skin,we have developed a flexible monolithic 3D-integrated tactile sensing system based on a holey MXene paste,where each vertical one-body unit simultaneously functions as a microsupercapacitor and pressure sensor.The in-plane mesopores of MXene significantly improve ion accessibility,mitigate the self-stacking of nanosheets,and allow the holey MXene to multifunctionally act as a sensing material,an active electrode,and a conductive interconnect,thus drastically reducing the interface mismatch and enhancing the mechanical robustness.Furthermore,we fabricate a large-scale device using a blade-coating and stamping method,which demonstrates excellent mechanical flexibility,low-power consumption,rapid response,and stable long-term operation.As a proof-of-concept application,we integrate our sensing array into a smart access control system,leveraging deep learning to accurately identify users based on their unique pressing behaviors.This study provides a promising approach for designing highly integrated,intelligent,and flexible electronic systems for advanced human-computer interactions and personalized electronics.
基金supported by the National Natural Science Foundation of China (Grant Nos.92580120 and 52471188)。
文摘Optimizing the microchannel design of the next generation of chips requires an understanding of the in situ property evolution of the chip-based materials under fast cooling.This work overcomes the conventional reliance on reheating data of melt-quenched glasses by demonstrating direct observations of glass transition on cooling curves utilizing the most advanced fast differential scanning calorimetry.By leveraging an MEMS chip sensor that allows for rapid heat extraction from microgram-sized samples to a purged gas coolant,the device is able to reach ultra-fast cooling rates of up to 40,000 K·s^(−1).Four thermal regions are identified by examining the cooling behaviors of two metallic glasses.This is because the actual rate of the specimen can differ from the programmed rate,especially at high set rate when the actual rate decreases before the glass transition is completed.We define the operational window for reliable cooling curve analysis,build models with empirical and theoretical analyses to determine the maximum feasible cooling rate,and demonstrate how optimizing sample mass and environment temperature broaden this window.The method avoids deceptive structural relaxation effects verified by fictivetemperature analysis and permits the capture of full glass transition during cooling.
基金supported by the Research Funds of the Center for Big Data and Population Health of IHM(grant number JKS2022015)the Key Scientific Research Fund of the Anhui Provincial Education Department(grant number2023AH050610)the Anhui Natural Science Foundation(grant number 1808085QH252)。
文摘In 2021,approximately 537 million people suffered from diabetes mellitus(DM)globally,and this figure will increase to approximately 783 million within the next quarter-century.The increasing burden of DM is a pressing global public health issue.Therefore,the early identification of high-risk groups and implementation of effective intervention measures is imperative.
文摘BACKGROUND Early screening,preoperative staging,and diagnosis of lymph node metastasis are crucial for improving the prognosis of gastric cancer(GC).AIM To evaluate the diagnostic value of combined multidetector computed tomography(MDCT)and gastrointestinal endoscopy for GC screening,preoperative staging,and lymph node metastasis detection,thereby providing a reference for clinical diagnosis and treatment.METHODS In this retrospective study clinical and imaging data of 134 patients with suspected GC who were admitted between January 2023 and October 2024 were initially reviewed.According to the inclusion and exclusion criteria,102 patients were finally enrolled in the analysis.All enrolled patients had undergone both MDCT and gastrointestinal endoscopy examinations prior to surgical intervention.Preoperative clinical staging and lymph node metastasis findings were compared with pathological results.RESULTS The combined use of MDCT and gastrointestinal endoscopy demonstrated a sensitivity of 98.53%,specificity of 97.06%,accuracy of 98.04%,positive predictive value of 98.53%,and negative predictive value of 97.06%for diagnosing GC.These factors were all significantly higher than those of MDCT or endoscopy alone(P<0.05).The accuracy rates of the combined approach for detecting clinical T and N stages were 97.06%and 92.65%,respectively,outperforming MDCT alone(86.76% and 79.41%)and endoscopy alone(85.29% and 70.59%)(P<0.05).Among 68 patients with confirmed GC,50(73.53%)were pathologically diagnosed with lymph node metastasis.The accuracy for detecting lymph node metastasis was 66.00%with endoscopy,76.00%with MDCT,and 92.00% with the combined approach,all with statistically significant differences(P<0.05).CONCLUSION The combined application of MDCT and gastrointestinal endoscopy enhanced diagnostic accuracy for GC,provided greater consistency in preoperative staging,and improved the detection of lymph node metastasis,thereby demonstrating significant clinical utility.
基金supported by the National Natural Science Foundation of China(Nos.22361162668 and 42021004)the National Key Research and Development Program of China(No.2023YFC3706203).
文摘Along with decrease of fine particulate matter(PM_(2.5))concentration in recent years in China,secondary species become increasingly important.This work focuses on characterizing secondary components,and a few important groups of organics including organic nitrogen(ON),organonitrates(OrgN),organosulfates(OS)and polycyclic aromatic hydrocarbons(PAHs),via online measurement of submicron aerosols(PM_(1))in Nanjing,China,during 2022 summer.The average PM_(1) concentration was 15.39μg/m^(3),dominated by secondary components(69.1%),which were even more important at higher PM_(1) levels.The primary organic aerosols(POA)were from traffic,industry and cooking;the two secondary OA factors were both closely linked with photochemistry,with one(OOA1)being relatively fresh and important in early afternoon and another(OOA2)being aged and important in late afternoon.Sulfate formation was also governed by photochemistry but resembled that of OOA2 not OOA1;nitrate formation was associated strongly with heterogeneous hydrolysis and thermodynamic equilibrium.Results also reveal a possible photochemical reaction channel from POA to OOA1,then to OOA2.Case studies show that formations of secondary components responded differently to different weather conditions and governed summer PM_(1) pollution.The average ON,OrgN,OS and PAHs concentrations were determined to be 122.8,84.4,45.6 and 3.3 ng/m^(3),respectively.ON was dominated by primary sources(53.8%).OrgN varied similarly to nitrate.OS formation was linked with aqueous-phase reactions,which were insignificant therefore its level was low.PAHs was mainly from traffic,and photochemical oxidation might be its important sink during afternoon.
基金support from the Natural Science Foundation of Jiangsu Province(Grant No.BK20240036)the National Natural Science Foundation of China(Grant Nos.U24A20515,22276099,and 22361162668)Guangxi Key Research and Development Program,China(Grant No.Guike AB24010074)。
文摘We conducted a field campaign to investigate the chemical composition,sources,and light absorption of submicron aerosols(PM_(1))from early 2022 in Nanjing,China.The average concentration of PM_(1) was 31μg m^(−3),organics(33%)constituted the largest fraction,followed by nitrate(30%),sulfate(18%),ammonium(15%),chloride(3%),and rBC(2%).Four organic aerosol(OA)subcomponents were identified,including two primary OA(POA)and two secondary OA(SOA).The less-oxidized SOA(LO-OOA)contributes the most to the total OA mass(59%).LO-OOA is tightly correlated with the tracer ion C_(2)H_(4)O_(2)^(+)from levoglucosan,and another aged biomass-burning derived species,K_(3)SO_(4)^(+),suggesting it was likely influenced by aged biomass-burning OA.Our study also revealed that fireworks during the Spring Festival have a detrimental impact on air quality,contributing to secondary formation and accumulation under static winter meteorological conditions,prolonging the pollution duration.Also,LO-OOA was found to have the strongest light-absorbing ability.Our results highlight that the light absorption of LO-OOA can mainly be attributed to the C_(x)H_(y)N^(+) family,increased with the double-bond equivalent value.The more-oxidized SOA(MO-OOA)exhibited a negligible light absorption and was strongly correlated with daytime photochemical processes,implying a light-bleaching effect.This study enhances our understanding of the regional contribution of biomass combustion and fireworks to PM_(1) pollution in Nanjing,a typical megacity in the Yangtze River Delta region,during winter,aiding in the development of strategies for long-term air quality improvement in the region.
