AIM:To evaluate and compare the efficacy of the astigmatic correction achieved with laser in situ keratomileusis(LASIK)in eyes with myopic astigmatism using wavefront-guided(WFG)and wavefront-optimized(WFO)ablation pr...AIM:To evaluate and compare the efficacy of the astigmatic correction achieved with laser in situ keratomileusis(LASIK)in eyes with myopic astigmatism using wavefront-guided(WFG)and wavefront-optimized(WFO)ablation profiles.METHODS:Prospective study included 221 eyes undergoing LASIK:99 and 122 eyes with low and moderate myopic astigmatism(low and moderate myopia groups).Two subgroups were differentiated in each group according to the ablation profile:WFG subgroup,109 eyes(45/64,low/moderate myopia groups)treated using the Advanced Custom Vue platform(Abbott Medical Optics Inc.),and WFO subgroup,112 eyes(54/58,low/moderate myopia groups)treated using the EX-500 platform(Alcon).Clinical outcomes were evaluated during a 6-month follow-up,including a vector analysis of astigmatic changes.RESULTS:Significantly better postoperative uncorrected visual acuity and efficacy index was found in the WFG subgroups of each group(P≤0.041).Postoperative spherical equivalent and cylinder were significantly higher in WFO subgroups(P≤0.003).In moderate myopia group,a higher percentage of eyes with a postoperative cylinder≤0.25 D was found in the WFG subgroup(90.6%vs 65.5%,P=0.002).In low and moderate myopia groups,the difference vector was significantly higher in the WFO subgroup compared to WFG(P〈0.001).In moderate myopia group,the magnitude(P=0.008)and angle of error(P〈0.001)were also significantly higher in the WFO subgroup.Significantlyless induction of high order aberrations were found with WFG treatments in both low and moderate myopia groups(P≤0.006).CONCLUSION:A more efficacious correction of myopic astigmatism providing a better visual outcome is achieved with WFG LASIK compared to WFO LASIK.展开更多
基金Partially supported by a grant from Abbott Medical Optics
文摘AIM:To evaluate and compare the efficacy of the astigmatic correction achieved with laser in situ keratomileusis(LASIK)in eyes with myopic astigmatism using wavefront-guided(WFG)and wavefront-optimized(WFO)ablation profiles.METHODS:Prospective study included 221 eyes undergoing LASIK:99 and 122 eyes with low and moderate myopic astigmatism(low and moderate myopia groups).Two subgroups were differentiated in each group according to the ablation profile:WFG subgroup,109 eyes(45/64,low/moderate myopia groups)treated using the Advanced Custom Vue platform(Abbott Medical Optics Inc.),and WFO subgroup,112 eyes(54/58,low/moderate myopia groups)treated using the EX-500 platform(Alcon).Clinical outcomes were evaluated during a 6-month follow-up,including a vector analysis of astigmatic changes.RESULTS:Significantly better postoperative uncorrected visual acuity and efficacy index was found in the WFG subgroups of each group(P≤0.041).Postoperative spherical equivalent and cylinder were significantly higher in WFO subgroups(P≤0.003).In moderate myopia group,a higher percentage of eyes with a postoperative cylinder≤0.25 D was found in the WFG subgroup(90.6%vs 65.5%,P=0.002).In low and moderate myopia groups,the difference vector was significantly higher in the WFO subgroup compared to WFG(P〈0.001).In moderate myopia group,the magnitude(P=0.008)and angle of error(P〈0.001)were also significantly higher in the WFO subgroup.Significantlyless induction of high order aberrations were found with WFG treatments in both low and moderate myopia groups(P≤0.006).CONCLUSION:A more efficacious correction of myopic astigmatism providing a better visual outcome is achieved with WFG LASIK compared to WFO LASIK.
