Extracting exosomes from bodily fluids offers a promising approach to overcoming inherent limitations,enabling the identification of potential biomarkers,especially those present in low abundance.^(1)PC-3 cells,known ...Extracting exosomes from bodily fluids offers a promising approach to overcoming inherent limitations,enabling the identification of potential biomarkers,especially those present in low abundance.^(1)PC-3 cells,known for their high metastatic potential compared with LNCaP cells,are widely used as a model for prostate cancer progression.^(2,3)How-ever,the mechanisms underlying their metastatic charac-teristics remain unclear.Therefore,there is a critical need to investigate diagnostic methods for prostate cancer,as current techniques have various limitations that can lead to overtreatment due to their lack of precision.展开更多
基金supported by grants from the National Research Foundation of Korea(NRF)(No.2022R1A2C109179013,RS-2024-00451519,RS-2024-00359310,2018R1A5A1024340)the National Research Council of Science&Technology(NST)Aging Convergence Research Center(Korea)(No.CRC22012-200)the Ministry of Health and Welfare of Korea(No.HV22C012800).
文摘Extracting exosomes from bodily fluids offers a promising approach to overcoming inherent limitations,enabling the identification of potential biomarkers,especially those present in low abundance.^(1)PC-3 cells,known for their high metastatic potential compared with LNCaP cells,are widely used as a model for prostate cancer progression.^(2,3)How-ever,the mechanisms underlying their metastatic charac-teristics remain unclear.Therefore,there is a critical need to investigate diagnostic methods for prostate cancer,as current techniques have various limitations that can lead to overtreatment due to their lack of precision.
