Multitarget stool DNA(mt-sDNA) testing was approved for average risk colorectal cancer(CRC) screening by the United States Food and Drug Administration and thereafter reimbursed for use by the Medicare program(2014).T...Multitarget stool DNA(mt-sDNA) testing was approved for average risk colorectal cancer(CRC) screening by the United States Food and Drug Administration and thereafter reimbursed for use by the Medicare program(2014).The United States Preventive Services Task Force(USPSTF) October 2015 draft recommendation for CRC screening included mt-s DNA as an "alternative" screening test that "may be useful in select clinical circumstances",despite its very high sensitivity for early stage CRC.The evidence supporting mt-s DNA for routine screening use is robust.The clinical efficacy of mt-s DNA as measured by sensitivity,specificity,life-years gained(LYG),and CRC deaths averted is similar to or exceeds that of the other more specifically recommended screening options included in the draft document,especially those requiring annual testing adherence.In a population with primarily irregular screening participation,tests with the highest point sensitivity and reasonable specificity are more likely to favorably impact CRC related morbidity and mortality than those depending on annual adherence.This paper reviews the evidence supporting mt-s DNA for routine screening and demonstrates,using USPSTF's modeling data,that mt-s DNA at three-year intervals provides significant clinical net benefits and fewer complications per LYG than annual fecal immunochemical testing,high sensitivity guaiac based fecal occult blood testing and 10-year colonoscopy screening.展开更多
Objectne:To screen children with influenza like illness or with symptoms of acute respiratory tract infections for influenza A virus infection-post swine flu pandemic era-using rapid influenza diagnostic tests.Methods...Objectne:To screen children with influenza like illness or with symptoms of acute respiratory tract infections for influenza A virus infection-post swine flu pandemic era-using rapid influenza diagnostic tests.Methods:During two year,(2010&2011),1200 children with influenza like illness or acute respiratory tract infections(according to World Health Organization criteria)were recruited.Their ages ranged from 2-60 months.Nasopharyngeal aspirates specimens were collected from all children for rapid influenza A diagnostic test.Results:Influenza A virus rapid test was positive in 47.5%of the children;the majority(89.6%)were presented with lower respiratory tract infections.Respiratory rate and temperature were significantly higher among positive rapid influenza test patients.Conclusions:Influenza A virus infection is still a major cause of respiratory tract infections in Egyptian children.It should be considered in all cases with cough and febrile episodes and influenza like symptoms even post swine flu pandemic.展开更多
MMT （Methadone maintenance treatment） is an effective way to treat opioid dependence. In Portugal, an MMT program has been available in pharmacies since January 1998, when a formal agreement was signed by the IDT, I...MMT （Methadone maintenance treatment） is an effective way to treat opioid dependence. In Portugal, an MMT program has been available in pharmacies since January 1998, when a formal agreement was signed by the IDT, I.P. （Institute on Drugs and Drug Addiction）, the PPS （Portuguese Pharmaceutical Society）, and the ANF （National Association of Pharmacies）. In January 2004, the INFARMED （National Authority of Medicine and Health Products） became a partner of the program. The possibility of continuing the treatment at a community pharmacy was restricted to patients receiving a stabilized dose of methadone at IDT, I.P. treatment centers. Pharmacists joining the MMT were given mandatory training. Patients on the MMT program received daily doses of methadone solution under directly observed therapy, and were followed up by trained pharmacists. From January 1998 to January 2013, 3,090 patients underwent MMT in Portuguese community pharmacies. The delivery of MMT at community pharmacy level is feasible. This strategy improves access and adherence to methadone treatment, thus helping to reduce the use of illegal opioids. Community pharmacists fully demonstrated their ability to perform extended roles in public health and harm-reduction strategies. Interaction and close cooperation between the different health professionals and organizations involved were crucial to achieve adequate support to the patients.展开更多
For this editorial,our colleague Dr.Naeema Hasan Al Qasseer,former World Health Organization(WHO)Senior Scientist of Nursing and Midwifery joins me to add her wisdom and experience on the topic of integrative maternal...For this editorial,our colleague Dr.Naeema Hasan Al Qasseer,former World Health Organization(WHO)Senior Scientist of Nursing and Midwifery joins me to add her wisdom and experience on the topic of integrative maternal-child health nursing.展开更多
Our infrastructure investment decisions matter enormously if infrastructure is to be long lived, so how can we select infrastructure investments that are optimum？ How do we determine what would be the best investment...Our infrastructure investment decisions matter enormously if infrastructure is to be long lived, so how can we select infrastructure investments that are optimum？ How do we determine what would be the best investments to make.展开更多
The Asian Journal of Andrology (AJA) was conceived at the First Asian & Oceanic Congress of Andrology in1992 by the Executive Council of the Asian Society of Andrology to be its official publication. Prof Shao-Zhe...The Asian Journal of Andrology (AJA) was conceived at the First Asian & Oceanic Congress of Andrology in1992 by the Executive Council of the Asian Society of Andrology to be its official publication. Prof Shao-Zhen QIANwas appointed the Editor-in-Chief, and Profs Zhi-Ping GU, Natwar R Kalla and Hiroyuld Oshima, the AssociateEditors-in-Chief. The Council delegated the production of AJA to the Shanghai Institute of Matefia Medica, Chinese展开更多
THERE has been a lot of talk of late about the internationalization of the Renminbi into a globally traded hard currency,but no one has yet designed a clear-cut road map on how to achieve that task.China needs to inco...THERE has been a lot of talk of late about the internationalization of the Renminbi into a globally traded hard currency,but no one has yet designed a clear-cut road map on how to achieve that task.China needs to incorporate this goal with a much wider and more comprehensive financial strategy that corresponds to the full potential ofits economic and monetary ambitions.展开更多
Objective： To develop a health-evaluating scale from a Chinese medicine（CM） perspective and reflecting CM conception of health. Methods： The Traditional Chinese Medicine Health Self-Evaluation Scale（TCM-50） was ...Objective： To develop a health-evaluating scale from a Chinese medicine（CM） perspective and reflecting CM conception of health. Methods： The Traditional Chinese Medicine Health Self-Evaluation Scale（TCM-50） was developed by verification of dimensions, formation of item pool, verification of scoring methodology, and pilot test of scale and item analysis. Results： TCM-50 composed of 50 items that could be classified into 4 dimensions including physiology and health, psychology and health, nature and health, and society and health. An examination of reliability and validity of TCM-50 yielded Cronbach＇s α coefficient of 0.927, and half coefficient of r was 0.876. The intraclass correlation coefficient of total score was 0.912. After using SF-36 questionnaire to evaluate the criterion validity, the Pearson r of the score of the two scales from the same participant was 0.740. Conclusions： TCM-50 has good reliability and validity, and can yield similar levels of efficacy as SF-36 in terms of evaluating people＇s overall health level. As a scale based on CM theory, TCM-50 is suitable for self-measuring the general health of Chinese patients.展开更多
The European Quantum Flagship set sail in October 2018 with its first roster of ambitious projects,encompassing 20 endeavours across a broad thematic horizon.Having reached the half-time mark of their three-year cours...The European Quantum Flagship set sail in October 2018 with its first roster of ambitious projects,encompassing 20 endeavours across a broad thematic horizon.Having reached the half-time mark of their three-year course,it is time for an evaluative first look at how they are performing on the journey towards the targets they had set out to reach-and how Europe itself is faring in the rapidly accelerating global competition to create breakthrough advances in quantum technology.展开更多
This paper uses intercultural identification and accommodation theories.Since Obama became US President on January 20,2009,he has widely demonstrated a considerable cultural transformation in his thinking toward the M...This paper uses intercultural identification and accommodation theories.Since Obama became US President on January 20,2009,he has widely demonstrated a considerable cultural transformation in his thinking toward the Middle East and Islam.Chinese Middle Eastern scholars’perspectives on US policies toward the Middle East and Islam include likely future positive developments by Obama.This paper assesses this transformation during his campaign,in the 2008-09 Gaza crisis bridge issue between the Bush and Obama administrations,with events occurring later,and his June 4,2009 address in Cairo,Egypt.展开更多
Xiaosong Ma:What inspired you to choose quantum optics as your major when you were a student,and can you share your experience or research journey in this field?Peter Knight:Quantum optics,as a discipline,was more or ...Xiaosong Ma:What inspired you to choose quantum optics as your major when you were a student,and can you share your experience or research journey in this field?Peter Knight:Quantum optics,as a discipline,was more or less formed during the time I’ve been active in the area.I started thinking about things that we would now call quantum optics in the middle of the 1960s when I was a student.展开更多
The 21st century has so far proven to provide a rough ride from time to time:it all started with the dot-com bubble bursting in the spring of the year 2000,continued after a period of economic recovery with the financ...The 21st century has so far proven to provide a rough ride from time to time:it all started with the dot-com bubble bursting in the spring of the year 2000,continued after a period of economic recovery with the financial crisis in 2008,fueled by cheap credit and lax lending standards that triggered a housing bubble and resulted in banks collapsing and many governments around the globe seeking to stabilize the financial economy at all cost.展开更多
Jimmy Carter,Palestine:Peace not Apartheid,NY:Simon and Schuster,2006.U.S.President and Nobel Peace Laureate,Jimmy Carter(1977-1981)has written nearly 20 books,including two on the Middle East,both The New York Times ...Jimmy Carter,Palestine:Peace not Apartheid,NY:Simon and Schuster,2006.U.S.President and Nobel Peace Laureate,Jimmy Carter(1977-1981)has written nearly 20 books,including two on the Middle East,both The New York Times bestsellers:The Blood of Abraham Insights into the Middle East published by Houghton Mifflin with printings and updates in 1985,1993,and 2007,and Palestine:Peace not Apartheid.Appearing on the English channel of Al Jazeera.展开更多
文摘Multitarget stool DNA(mt-sDNA) testing was approved for average risk colorectal cancer(CRC) screening by the United States Food and Drug Administration and thereafter reimbursed for use by the Medicare program(2014).The United States Preventive Services Task Force(USPSTF) October 2015 draft recommendation for CRC screening included mt-s DNA as an "alternative" screening test that "may be useful in select clinical circumstances",despite its very high sensitivity for early stage CRC.The evidence supporting mt-s DNA for routine screening use is robust.The clinical efficacy of mt-s DNA as measured by sensitivity,specificity,life-years gained(LYG),and CRC deaths averted is similar to or exceeds that of the other more specifically recommended screening options included in the draft document,especially those requiring annual testing adherence.In a population with primarily irregular screening participation,tests with the highest point sensitivity and reasonable specificity are more likely to favorably impact CRC related morbidity and mortality than those depending on annual adherence.This paper reviews the evidence supporting mt-s DNA for routine screening and demonstrates,using USPSTF's modeling data,that mt-s DNA at three-year intervals provides significant clinical net benefits and fewer complications per LYG than annual fecal immunochemical testing,high sensitivity guaiac based fecal occult blood testing and 10-year colonoscopy screening.
文摘Objectne:To screen children with influenza like illness or with symptoms of acute respiratory tract infections for influenza A virus infection-post swine flu pandemic era-using rapid influenza diagnostic tests.Methods:During two year,(2010&2011),1200 children with influenza like illness or acute respiratory tract infections(according to World Health Organization criteria)were recruited.Their ages ranged from 2-60 months.Nasopharyngeal aspirates specimens were collected from all children for rapid influenza A diagnostic test.Results:Influenza A virus rapid test was positive in 47.5%of the children;the majority(89.6%)were presented with lower respiratory tract infections.Respiratory rate and temperature were significantly higher among positive rapid influenza test patients.Conclusions:Influenza A virus infection is still a major cause of respiratory tract infections in Egyptian children.It should be considered in all cases with cough and febrile episodes and influenza like symptoms even post swine flu pandemic.
文摘MMT （Methadone maintenance treatment） is an effective way to treat opioid dependence. In Portugal, an MMT program has been available in pharmacies since January 1998, when a formal agreement was signed by the IDT, I.P. （Institute on Drugs and Drug Addiction）, the PPS （Portuguese Pharmaceutical Society）, and the ANF （National Association of Pharmacies）. In January 2004, the INFARMED （National Authority of Medicine and Health Products） became a partner of the program. The possibility of continuing the treatment at a community pharmacy was restricted to patients receiving a stabilized dose of methadone at IDT, I.P. treatment centers. Pharmacists joining the MMT were given mandatory training. Patients on the MMT program received daily doses of methadone solution under directly observed therapy, and were followed up by trained pharmacists. From January 1998 to January 2013, 3,090 patients underwent MMT in Portuguese community pharmacies. The delivery of MMT at community pharmacy level is feasible. This strategy improves access and adherence to methadone treatment, thus helping to reduce the use of illegal opioids. Community pharmacists fully demonstrated their ability to perform extended roles in public health and harm-reduction strategies. Interaction and close cooperation between the different health professionals and organizations involved were crucial to achieve adequate support to the patients.
文摘For this editorial,our colleague Dr.Naeema Hasan Al Qasseer,former World Health Organization(WHO)Senior Scientist of Nursing and Midwifery joins me to add her wisdom and experience on the topic of integrative maternal-child health nursing.
文摘Our infrastructure investment decisions matter enormously if infrastructure is to be long lived, so how can we select infrastructure investments that are optimum？ How do we determine what would be the best investments to make.
文摘The Asian Journal of Andrology (AJA) was conceived at the First Asian & Oceanic Congress of Andrology in1992 by the Executive Council of the Asian Society of Andrology to be its official publication. Prof Shao-Zhen QIANwas appointed the Editor-in-Chief, and Profs Zhi-Ping GU, Natwar R Kalla and Hiroyuld Oshima, the AssociateEditors-in-Chief. The Council delegated the production of AJA to the Shanghai Institute of Matefia Medica, Chinese
文摘THERE has been a lot of talk of late about the internationalization of the Renminbi into a globally traded hard currency,but no one has yet designed a clear-cut road map on how to achieve that task.China needs to incorporate this goal with a much wider and more comprehensive financial strategy that corresponds to the full potential ofits economic and monetary ambitions.
基金Supported by Beijing Youth Talent Plan(No.YETP0787)Youth Teacher Fund of Beijing University of Chinese Medicine
文摘Objective： To develop a health-evaluating scale from a Chinese medicine（CM） perspective and reflecting CM conception of health. Methods： The Traditional Chinese Medicine Health Self-Evaluation Scale（TCM-50） was developed by verification of dimensions, formation of item pool, verification of scoring methodology, and pilot test of scale and item analysis. Results： TCM-50 composed of 50 items that could be classified into 4 dimensions including physiology and health, psychology and health, nature and health, and society and health. An examination of reliability and validity of TCM-50 yielded Cronbach＇s α coefficient of 0.927, and half coefficient of r was 0.876. The intraclass correlation coefficient of total score was 0.912. After using SF-36 questionnaire to evaluate the criterion validity, the Pearson r of the score of the two scales from the same participant was 0.740. Conclusions： TCM-50 has good reliability and validity, and can yield similar levels of efficacy as SF-36 in terms of evaluating people＇s overall health level. As a scale based on CM theory, TCM-50 is suitable for self-measuring the general health of Chinese patients.
文摘The European Quantum Flagship set sail in October 2018 with its first roster of ambitious projects,encompassing 20 endeavours across a broad thematic horizon.Having reached the half-time mark of their three-year course,it is time for an evaluative first look at how they are performing on the journey towards the targets they had set out to reach-and how Europe itself is faring in the rapidly accelerating global competition to create breakthrough advances in quantum technology.
文摘This paper uses intercultural identification and accommodation theories.Since Obama became US President on January 20,2009,he has widely demonstrated a considerable cultural transformation in his thinking toward the Middle East and Islam.Chinese Middle Eastern scholars’perspectives on US policies toward the Middle East and Islam include likely future positive developments by Obama.This paper assesses this transformation during his campaign,in the 2008-09 Gaza crisis bridge issue between the Bush and Obama administrations,with events occurring later,and his June 4,2009 address in Cairo,Egypt.
文摘Xiaosong Ma:What inspired you to choose quantum optics as your major when you were a student,and can you share your experience or research journey in this field?Peter Knight:Quantum optics,as a discipline,was more or less formed during the time I’ve been active in the area.I started thinking about things that we would now call quantum optics in the middle of the 1960s when I was a student.
文摘The 21st century has so far proven to provide a rough ride from time to time:it all started with the dot-com bubble bursting in the spring of the year 2000,continued after a period of economic recovery with the financial crisis in 2008,fueled by cheap credit and lax lending standards that triggered a housing bubble and resulted in banks collapsing and many governments around the globe seeking to stabilize the financial economy at all cost.
文摘Jimmy Carter,Palestine:Peace not Apartheid,NY:Simon and Schuster,2006.U.S.President and Nobel Peace Laureate,Jimmy Carter(1977-1981)has written nearly 20 books,including two on the Middle East,both The New York Times bestsellers:The Blood of Abraham Insights into the Middle East published by Houghton Mifflin with printings and updates in 1985,1993,and 2007,and Palestine:Peace not Apartheid.Appearing on the English channel of Al Jazeera.
