Sepsis is characterized by immune dysregulation that are responsible for an increase in secondary in-fections and mortality.Acupuncture is a potential alternative treatment for sepsis.In this comprehensive literature ...Sepsis is characterized by immune dysregulation that are responsible for an increase in secondary in-fections and mortality.Acupuncture is a potential alternative treatment for sepsis.In this comprehensive literature review,we found that acupuncture is beneficial in treating immune disorders associated with sepsis.Acupuncture can improve immune disorders associated with sepsis and regulate the functions of innate and adaptive immune cells.Specifically,acupuncture can reduce the number of neutrophils in sep-sis,promote the polarization of macrophages towards M2-like macrophages,and alleviate inflammation by reducing the activation of microglia and astrocytes.Furthermore,acupuncture can increase the per-centage of T cells and modulate the balance between T cell subsets.The immunomodulatory mechanism of acupuncture in sepsis may be attributed to the balance of the autonomic nervous system,including activation of the sympathetic-adrenal axis,vagal-cholinergic pathway,and vagal-adrenal axis.In addition,acupuncture can inhibit inflammation by preserving the integrity of the intestinal barrier and regulating the composition of the intestinal microbiota.Clinical studies have also demonstrated that acupuncture can enhance the number of peripheral natural killer(NK)cells and T cell subsets,as well as the expres-sion of human leukocyte antigen DR(HLA-DR).Moreover,acupuncture can decrease the ratio of white blood cells to neutrophils and reduce the levels of inflammatory factors.Therefore,acupuncture has the potential to improve immune function in sepsis.Further investigation of its mechanism is expected to provide a scientific and reliable foundation for the application of acupuncture in sepsis treatment.展开更多
Objective To observe acupuncture effects, we analyze the function of Histamine on acupoints, and provide evidence for the research on generation mechanism of the acupuncture effects.
This study established the following groups of rats： a normal group, a sham surgery group, a spinal cord injury model group, a low-frequency electroacupuncture group, a high-frequency electroacupuncture group and a s...This study established the following groups of rats： a normal group, a sham surgery group, a spinal cord injury model group, a low-frequency electroacupuncture group, a high-frequency electroacupuncture group and a semen coicis group. In all but the normal and sham surgery groups the left half of Tlo was transected. Four hours after model induction, 5-Hz and 100-Hz electroacupuncture were used to stimulate the acupoints I-luantiao （GB 30）, Zusan/i （ST 36）, Zhiyan9 （DU 9） and Xuanshu （DU 5）, or crude extract from semen coicis was intraperitoneally injected, for 8 consecutive weeks. The results indicated that electroacupuncture stimulation and intraperitoneal injection of semen coicis improved the morphology of spinal cord tissue, promoted the recovery of motion-evoked potentials, suppressed glial fibrillary acidic protein expression, and ameliorated motor function in rats with hemisection spinal cord injury. The effects of high-frequency （100 Hz） electroacupuncture ancl semen coicis were significant.展开更多
Acupuncture,with its unique set of theories and its evident results in clinical practice is an important part of traditional Chinese medicine(TCM),and gaining recognition worldwide for the past few years.Although acup...Acupuncture,with its unique set of theories and its evident results in clinical practice is an important part of traditional Chinese medicine(TCM),and gaining recognition worldwide for the past few years.Although acupuncture treatment is generally accepted by the public,a few western researchers believe that sufficient evidence of its efficiency is still currently lacking,therefore creating a challenge of its acceptance on a wider scale.This article suggests the concepts of acupuncture behind clinical researches by reviewing the clinical researches done,analyzing the existing problems,and integrating real life acupuncture into the research process.By increasing the credibility of acupuncture,its reach can be extended globally and to more countries and regions.展开更多
A rat model of middle cerebral artery permanent occlusion was established using the modified Longa method. Successfully established model animals were treated by blood-letting puncture at twelve Jing-Well points of th...A rat model of middle cerebral artery permanent occlusion was established using the modified Longa method. Successfully established model animals were treated by blood-letting puncture at twelve Jing-Well points of the hand, and/or by injecting mannitol into the caudal vein twice daily. Brain tissue was collected at 24, 48 and 72 hours after modeling, and blood was collected through the retinal vein before Evans blue was injected, approximately 1 hour prior to harvesting of brain tissue. Results showed that Evans blue leakage into brain tissue and serum nitric oxide synthase activity were significantly increased in model rats. Treatment with blood-letting punctures at twelve Jing-Well points of the hand and/or injection of mannitol into the caudal vein reduced the amount of Evans blue leakage into the brain tissue and serum nitric oxide synthase activity to varying degrees. There was no significant difference between single treatment and combined treatment. Experimental findings indicate that blood-letting punctures at twelve Jing-Well points of the hand can decrease blood-brain barrier permeability and serum nitric oxide synthase activity in rats following middle cerebral artery occlusion, and its effect is similar to that of mannitol injection alone and Jing-Well points plus mannitol injection.展开更多
The scientific evidenee of acupuncture studies has been improved in recent years,and one of the important manifestations is that more and more acupuncture clinical trials and mechanism researches have been published i...The scientific evidenee of acupuncture studies has been improved in recent years,and one of the important manifestations is that more and more acupuncture clinical trials and mechanism researches have been published in the source periodicals of Science Citation Index(SCI).This study summarized the dominant diseases of acupuncture focusing on of acupuncture efficacy and mechanisms,and discussed the existing problems,highlight!ng the directi on of future developme nts.Most clinical studies were published in journals with journal impact factor(JIF)score of 10 or above,and majority of the basic researches had JIF scores of 5 to 10.The above literature were further divided according to the International Classification of Diseases(ICD).The most concerned diseases in these articles were neurological diseases,musculoskeletal system and connective tissue diseases,tumor and digestive system diseases.The therapeutic effect and mechanism of acupuncture on each kind of disease were summarized.The results showed that the therapeutic effect of acupuncture on nerve injury focused on the anti-oxidation pathway,neuroprotective and anti-inflammatory processes.The antiinflammatory effect also played an important role in the treatme nt of musculoskeletal diseases.The an algesic effect was underlined in most of these studies.Clinical trials were well carried out on acupuncture curative effect of tumor complications and side effects of chemo-radiotherapy,but the potential mechanisms have not been clarified.Somato-visceral reflex was suggested to be strongly associated with the effects of acupuncture changing the motor activity of the gastrointestinal tract.Functional magnetic resonance imaging studies indicated that non-specific effects play important roles in acupuncture analgesia.Lines of evidenee have pointed out that the regulation of neuro-endocrine-immune networks may be a common switch of acupuncture on different nerve system diseases.展开更多
Objective To evaluate the quality of the existing studies and summarize evidence of important outcomes of meta-analyses/systematic reviews(MAs/SRs)of CFS.Methods Potentially eligible studies were searched in the follo...Objective To evaluate the quality of the existing studies and summarize evidence of important outcomes of meta-analyses/systematic reviews(MAs/SRs)of CFS.Methods Potentially eligible studies were searched in the following electronic databases from inception to 1 September,2019:Chinese Biomedical Literature Database(CBM),China Science and Technology Journal Database(VIP),China National Knowledge Infrastructure(CNKI),WanFang Database(WF),Web of Science,Embase,PubMed and Cochrane Library.Grades of Recommendation,Assessment,Development,and Evaluation(GRADE)was used to evaluate the quality of evidence.The methodological quality of the literature was evaluated by A Measure Tool to Assess Systematic Reviews-2(AMSTAR-2)and the quality of the report was assessed by Preferred Reporting Items for Systematic Reviews and Meta-analyses(PRISMA).The intra-class correlation coefficient was used to assess the consistency of the reviewers,with an overall intraclass correlation coefficient score of 0.967.Results Ten MAs/SRs were included.The overall conclusions were that acupuncture had good safety and efficacy in the treatment of CFS,but some of these results were contradictory.The GRADE indicated that out of the 17 outcomes,high-quality evidence was provided in 0(0%),moderate in 3(17.65%),low in 10(58.82%),and very low in 4(23.53%).The results of AMSTAR-2 showed that the methodological quality of all included studies was critically low.The PRISMA statement revealed that 8 articles(80%)were in line with 20 of the 27-item checklist,and 2 articles(20%)matched with 10-19 of the 27 items.Conclusion We found that acupuncture on treating CFS has the advantage for efficacy and safety,but the quality of SRs/MAs of acupuncture for CFS need to be improved.展开更多
Objective To assess the effect and safety of bloodletting puncture at hand twelve Jing-Well points(HTWPs)in acute stroke patients with conscious disturbance.Methods In this multi-center and randomized controlled trial...Objective To assess the effect and safety of bloodletting puncture at hand twelve Jing-Well points(HTWPs)in acute stroke patients with conscious disturbance.Methods In this multi-center and randomized controlled trial,360 patients suffered from ischemic or hemorrhagic stroke with conscious disturbance within 48 h from the onset of symptom were divided into bloodletting(180 cases)and control(180 cases)groups using a block randomization.Patients in both groups received routine Western medicine,and patients in the bloodletting group received additional bloodletting puncture at HTWPs on admission immediately before conventional treatment.The primary outcome measure was Glasgow Coma Scale(GCS)score and the secondary outcomes included blood pressure,respiratory rate and pulse rate.All variables were evaluated at baseline(before bloodletting),0(after bloodletting immediately),15,30,50 and 80 min post bloodletting.Results At 80 min post bloodletting,the proportion of patients with improved consciousness in the bloodletting group was greater than the control group(P<0.05).In the separate analysis of moderate consciousness disturbance subgroup,bloodletting therapy benefited ischemic patients,and improved the eye and language response of GCS score at 15,30,50,80 min post bloodletting(P<0.05 or P<0.01).No significant differences were observed regarding the secondary outcomes between two groups(P>0.05).Conclusion The bloodletting puncture at HTWPs was safe and could improve conscious levels of ischemic stroke patients,highlighting a first-aid intervention for acute stroke.展开更多
Information of the acupuncture treatment of depression in 93 ancient books has been made statistics with computer. Results showed that Heart Meridian, Pericardium Meridian, Bladder Meridian, Governor Vessel, Conceptio...Information of the acupuncture treatment of depression in 93 ancient books has been made statistics with computer. Results showed that Heart Meridian, Pericardium Meridian, Bladder Meridian, Governor Vessel, Conception Vessel, Spleen Meridian and Stomach Meridian have been used frequently; as to areas, the medial aspect of upper limbs, head and face, medial aspect of legs, upper back, chest and abdomen have been mostly selected; as to treatment methods, needling, moxibustion and blood-letting therapies have been utilized. Key Words Depression - Acupuncture-Moxibustion - Incunabula Foundation Item: This study supported by Shanghai Science and Technology Committee (NO. 02DZ19150-2)Translator: XIAO Yuan-chun展开更多
Brain-activating and orifice-opening acupuncture treatment has a marked clinical effect on apoplexy. It is clinically appropriate for many conditions, such as apoplectic sequela, complications and dementia. The basic ...Brain-activating and orifice-opening acupuncture treatment has a marked clinical effect on apoplexy. It is clinically appropriate for many conditions, such as apoplectic sequela, complications and dementia. The basic research has showed that the brain-activating and orifice-opening acupuncture promotes the synthesis of nitric oxide (NO) in blood and brain tissues → raises NO conten_→ improves autonomic microvascular movement → ameliorates microcirculation; increases the activity of superoxide dismutase (SOD), lowers lipid peroxide (LPO) content and reduces a cerebral injury due to oxidation; decreases Ca2+ flow into cells and lightens Ca2+ overload; regulates abnormal metabolism of central neurotransmitters and lessens cerebrocellular necrosis or apoptosis. Needling point Shuigou (GV 26) can markedly reduce cerebral energy metabolism, protect cerebral cells and increase the mRNA expression of cholecystokinin in rat’s brain. Needling point Neiguan (PC 6) excites thalamic dorsomedial nucleus. Needling points Shuigou (GV 26) and Neiguan (PC 6) in old mice increases the number of active genes in cerebrocellular and hepatocellular nuclei, decreases nuclear membrane protein accumulated abnormally in hepatocellular and cerebrocellular nuclei, increases part of chromatinic nonhistone protein and improves the ability to regulate and control active gene transcription. SHI Xue-min. Academician of China Academy of Engineering Sciences, director of First Hospital Affiliated to Tianjin College of TCM, vice president of the China Academy of Acupuncture and Moxbustion, supervisor of postgraduate for doctorate, professor, and senior consultant doctor. He has been long engaged in clinical and experimental research on treating apoplexy with brain-activating and orifice-opening acupuncture.展开更多
Objective： To compare the difference of infrared radiation temperature on body surface of points between healthy people and patients with hyperplasia of mammary glands. Method： The thermaCATMT P30 infrared thermal i...Objective： To compare the difference of infrared radiation temperature on body surface of points between healthy people and patients with hyperplasia of mammary glands. Method： The thermaCATMT P30 infrared thermal imaging system was selected to measure the infrared radiation temperature on body surface of eight points in four meridians in 74 patients with hyperplasia of mammary glands and 63 healthy people. Results： The infrared radiation temperatures on body surface of right Youmen （KI 21） in cases with hyperplasia of mammary glands were significantly higher than the healthy people （P=-0.009）, and the infrared radiation temperatures on left Youmen （KI 21） and other points had no significant difference with healthy people （P〉0.05）. Conclusion： The infrared radiation temperatures on body surface of right Youmen （KI 21） have significant differences with healthy people. This might occur because of the pathogenesis of hyperplasia of mammary glands and of the specificity of the point Youmen （KI 21）.展开更多
In the systematical study on moving cupping method by combination of the clinical practice, the time, speed and strength of moving cupping method are quantified. 15 basic manual techniques of moving cupping methods ha...In the systematical study on moving cupping method by combination of the clinical practice, the time, speed and strength of moving cupping method are quantified. 15 basic manual techniques of moving cupping methods have been summarized and 10 clinical application protocols have been recommended. In accordance with acupuncture theory, the concept of ＂three-layer moving cupping method＂ has been submitted, in the knowledge that different manual techniques, different protocols in the clinical application can produce different therapeutic effects of different therapies like warming moxibustion, cupping method, scratching method, massage and herbal therapy.展开更多
基金Supported by the National Natural Science Foundation of China:No.82374563,82004467,82305370China Postdoctoral Science Foundation:No.2022M721536+1 种基金Tianjin Graduate Research Innovation Project:2022BKY177TUTCM Graduate Research Innovation Project:YJSKC-20221016。
文摘Sepsis is characterized by immune dysregulation that are responsible for an increase in secondary in-fections and mortality.Acupuncture is a potential alternative treatment for sepsis.In this comprehensive literature review,we found that acupuncture is beneficial in treating immune disorders associated with sepsis.Acupuncture can improve immune disorders associated with sepsis and regulate the functions of innate and adaptive immune cells.Specifically,acupuncture can reduce the number of neutrophils in sep-sis,promote the polarization of macrophages towards M2-like macrophages,and alleviate inflammation by reducing the activation of microglia and astrocytes.Furthermore,acupuncture can increase the per-centage of T cells and modulate the balance between T cell subsets.The immunomodulatory mechanism of acupuncture in sepsis may be attributed to the balance of the autonomic nervous system,including activation of the sympathetic-adrenal axis,vagal-cholinergic pathway,and vagal-adrenal axis.In addition,acupuncture can inhibit inflammation by preserving the integrity of the intestinal barrier and regulating the composition of the intestinal microbiota.Clinical studies have also demonstrated that acupuncture can enhance the number of peripheral natural killer(NK)cells and T cell subsets,as well as the expres-sion of human leukocyte antigen DR(HLA-DR).Moreover,acupuncture can decrease the ratio of white blood cells to neutrophils and reduce the levels of inflammatory factors.Therefore,acupuncture has the potential to improve immune function in sepsis.Further investigation of its mechanism is expected to provide a scientific and reliable foundation for the application of acupuncture in sepsis treatment.
文摘Objective To observe acupuncture effects, we analyze the function of Histamine on acupoints, and provide evidence for the research on generation mechanism of the acupuncture effects.
基金the High-funded Projects of Japan Science and Technology Ministry,No. 343the National Natural Science Foundation of China,No. 30772838
文摘This study established the following groups of rats： a normal group, a sham surgery group, a spinal cord injury model group, a low-frequency electroacupuncture group, a high-frequency electroacupuncture group and a semen coicis group. In all but the normal and sham surgery groups the left half of Tlo was transected. Four hours after model induction, 5-Hz and 100-Hz electroacupuncture were used to stimulate the acupoints I-luantiao （GB 30）, Zusan/i （ST 36）, Zhiyan9 （DU 9） and Xuanshu （DU 5）, or crude extract from semen coicis was intraperitoneally injected, for 8 consecutive weeks. The results indicated that electroacupuncture stimulation and intraperitoneal injection of semen coicis improved the morphology of spinal cord tissue, promoted the recovery of motion-evoked potentials, suppressed glial fibrillary acidic protein expression, and ameliorated motor function in rats with hemisection spinal cord injury. The effects of high-frequency （100 Hz） electroacupuncture ancl semen coicis were significant.
文摘Acupuncture,with its unique set of theories and its evident results in clinical practice is an important part of traditional Chinese medicine(TCM),and gaining recognition worldwide for the past few years.Although acupuncture treatment is generally accepted by the public,a few western researchers believe that sufficient evidence of its efficiency is still currently lacking,therefore creating a challenge of its acceptance on a wider scale.This article suggests the concepts of acupuncture behind clinical researches by reviewing the clinical researches done,analyzing the existing problems,and integrating real life acupuncture into the research process.By increasing the credibility of acupuncture,its reach can be extended globally and to more countries and regions.
基金sponsored by the Open Research Fund of Zhejiang First-foremost Key Subject-Acupuncture & Moxibustion,No. ZTK2010A07
文摘A rat model of middle cerebral artery permanent occlusion was established using the modified Longa method. Successfully established model animals were treated by blood-letting puncture at twelve Jing-Well points of the hand, and/or by injecting mannitol into the caudal vein twice daily. Brain tissue was collected at 24, 48 and 72 hours after modeling, and blood was collected through the retinal vein before Evans blue was injected, approximately 1 hour prior to harvesting of brain tissue. Results showed that Evans blue leakage into brain tissue and serum nitric oxide synthase activity were significantly increased in model rats. Treatment with blood-letting punctures at twelve Jing-Well points of the hand and/or injection of mannitol into the caudal vein reduced the amount of Evans blue leakage into the brain tissue and serum nitric oxide synthase activity to varying degrees. There was no significant difference between single treatment and combined treatment. Experimental findings indicate that blood-letting punctures at twelve Jing-Well points of the hand can decrease blood-brain barrier permeability and serum nitric oxide synthase activity in rats following middle cerebral artery occlusion, and its effect is similar to that of mannitol injection alone and Jing-Well points plus mannitol injection.
基金the National Natural Science Foundation of China(Nos.81704146,81503637 and 81503636)the Natural Science Foundation of Tianjin(No.16JCYBJC43500)。
文摘The scientific evidenee of acupuncture studies has been improved in recent years,and one of the important manifestations is that more and more acupuncture clinical trials and mechanism researches have been published in the source periodicals of Science Citation Index(SCI).This study summarized the dominant diseases of acupuncture focusing on of acupuncture efficacy and mechanisms,and discussed the existing problems,highlight!ng the directi on of future developme nts.Most clinical studies were published in journals with journal impact factor(JIF)score of 10 or above,and majority of the basic researches had JIF scores of 5 to 10.The above literature were further divided according to the International Classification of Diseases(ICD).The most concerned diseases in these articles were neurological diseases,musculoskeletal system and connective tissue diseases,tumor and digestive system diseases.The therapeutic effect and mechanism of acupuncture on each kind of disease were summarized.The results showed that the therapeutic effect of acupuncture on nerve injury focused on the anti-oxidation pathway,neuroprotective and anti-inflammatory processes.The antiinflammatory effect also played an important role in the treatme nt of musculoskeletal diseases.The an algesic effect was underlined in most of these studies.Clinical trials were well carried out on acupuncture curative effect of tumor complications and side effects of chemo-radiotherapy,but the potential mechanisms have not been clarified.Somato-visceral reflex was suggested to be strongly associated with the effects of acupuncture changing the motor activity of the gastrointestinal tract.Functional magnetic resonance imaging studies indicated that non-specific effects play important roles in acupuncture analgesia.Lines of evidenee have pointed out that the regulation of neuro-endocrine-immune networks may be a common switch of acupuncture on different nerve system diseases.
基金the National Natural Science Foundation of China(No.81590951 and No.81722050)。
文摘Objective To evaluate the quality of the existing studies and summarize evidence of important outcomes of meta-analyses/systematic reviews(MAs/SRs)of CFS.Methods Potentially eligible studies were searched in the following electronic databases from inception to 1 September,2019:Chinese Biomedical Literature Database(CBM),China Science and Technology Journal Database(VIP),China National Knowledge Infrastructure(CNKI),WanFang Database(WF),Web of Science,Embase,PubMed and Cochrane Library.Grades of Recommendation,Assessment,Development,and Evaluation(GRADE)was used to evaluate the quality of evidence.The methodological quality of the literature was evaluated by A Measure Tool to Assess Systematic Reviews-2(AMSTAR-2)and the quality of the report was assessed by Preferred Reporting Items for Systematic Reviews and Meta-analyses(PRISMA).The intra-class correlation coefficient was used to assess the consistency of the reviewers,with an overall intraclass correlation coefficient score of 0.967.Results Ten MAs/SRs were included.The overall conclusions were that acupuncture had good safety and efficacy in the treatment of CFS,but some of these results were contradictory.The GRADE indicated that out of the 17 outcomes,high-quality evidence was provided in 0(0%),moderate in 3(17.65%),low in 10(58.82%),and very low in 4(23.53%).The results of AMSTAR-2 showed that the methodological quality of all included studies was critically low.The PRISMA statement revealed that 8 articles(80%)were in line with 20 of the 27-item checklist,and 2 articles(20%)matched with 10-19 of the 27 items.Conclusion We found that acupuncture on treating CFS has the advantage for efficacy and safety,but the quality of SRs/MAs of acupuncture for CFS need to be improved.
基金Supported by the National Basic Research Program of China(No.2014CB543201)Clinic Study for Acupoints Dictionary of People’s Republic of China(No.03XDLZ14)。
文摘Objective To assess the effect and safety of bloodletting puncture at hand twelve Jing-Well points(HTWPs)in acute stroke patients with conscious disturbance.Methods In this multi-center and randomized controlled trial,360 patients suffered from ischemic or hemorrhagic stroke with conscious disturbance within 48 h from the onset of symptom were divided into bloodletting(180 cases)and control(180 cases)groups using a block randomization.Patients in both groups received routine Western medicine,and patients in the bloodletting group received additional bloodletting puncture at HTWPs on admission immediately before conventional treatment.The primary outcome measure was Glasgow Coma Scale(GCS)score and the secondary outcomes included blood pressure,respiratory rate and pulse rate.All variables were evaluated at baseline(before bloodletting),0(after bloodletting immediately),15,30,50 and 80 min post bloodletting.Results At 80 min post bloodletting,the proportion of patients with improved consciousness in the bloodletting group was greater than the control group(P<0.05).In the separate analysis of moderate consciousness disturbance subgroup,bloodletting therapy benefited ischemic patients,and improved the eye and language response of GCS score at 15,30,50,80 min post bloodletting(P<0.05 or P<0.01).No significant differences were observed regarding the secondary outcomes between two groups(P>0.05).Conclusion The bloodletting puncture at HTWPs was safe and could improve conscious levels of ischemic stroke patients,highlighting a first-aid intervention for acute stroke.
文摘Information of the acupuncture treatment of depression in 93 ancient books has been made statistics with computer. Results showed that Heart Meridian, Pericardium Meridian, Bladder Meridian, Governor Vessel, Conception Vessel, Spleen Meridian and Stomach Meridian have been used frequently; as to areas, the medial aspect of upper limbs, head and face, medial aspect of legs, upper back, chest and abdomen have been mostly selected; as to treatment methods, needling, moxibustion and blood-letting therapies have been utilized. Key Words Depression - Acupuncture-Moxibustion - Incunabula Foundation Item: This study supported by Shanghai Science and Technology Committee (NO. 02DZ19150-2)Translator: XIAO Yuan-chun
文摘Brain-activating and orifice-opening acupuncture treatment has a marked clinical effect on apoplexy. It is clinically appropriate for many conditions, such as apoplectic sequela, complications and dementia. The basic research has showed that the brain-activating and orifice-opening acupuncture promotes the synthesis of nitric oxide (NO) in blood and brain tissues → raises NO conten_→ improves autonomic microvascular movement → ameliorates microcirculation; increases the activity of superoxide dismutase (SOD), lowers lipid peroxide (LPO) content and reduces a cerebral injury due to oxidation; decreases Ca2+ flow into cells and lightens Ca2+ overload; regulates abnormal metabolism of central neurotransmitters and lessens cerebrocellular necrosis or apoptosis. Needling point Shuigou (GV 26) can markedly reduce cerebral energy metabolism, protect cerebral cells and increase the mRNA expression of cholecystokinin in rat’s brain. Needling point Neiguan (PC 6) excites thalamic dorsomedial nucleus. Needling points Shuigou (GV 26) and Neiguan (PC 6) in old mice increases the number of active genes in cerebrocellular and hepatocellular nuclei, decreases nuclear membrane protein accumulated abnormally in hepatocellular and cerebrocellular nuclei, increases part of chromatinic nonhistone protein and improves the ability to regulate and control active gene transcription. SHI Xue-min. Academician of China Academy of Engineering Sciences, director of First Hospital Affiliated to Tianjin College of TCM, vice president of the China Academy of Acupuncture and Moxbustion, supervisor of postgraduate for doctorate, professor, and senior consultant doctor. He has been long engaged in clinical and experimental research on treating apoplexy with brain-activating and orifice-opening acupuncture.
基金State 973 plan (2005CB523306)National Natural Science Foundation (30572306)+1 种基金Shanghai Municipal Education Commission Project (07CZ034)State Administration of Traditional Chinese Medicine and Shanghai Leading Academic Discipline Project (T0304,T0302)
文摘Objective： To compare the difference of infrared radiation temperature on body surface of points between healthy people and patients with hyperplasia of mammary glands. Method： The thermaCATMT P30 infrared thermal imaging system was selected to measure the infrared radiation temperature on body surface of eight points in four meridians in 74 patients with hyperplasia of mammary glands and 63 healthy people. Results： The infrared radiation temperatures on body surface of right Youmen （KI 21） in cases with hyperplasia of mammary glands were significantly higher than the healthy people （P=-0.009）, and the infrared radiation temperatures on left Youmen （KI 21） and other points had no significant difference with healthy people （P〉0.05）. Conclusion： The infrared radiation temperatures on body surface of right Youmen （KI 21） have significant differences with healthy people. This might occur because of the pathogenesis of hyperplasia of mammary glands and of the specificity of the point Youmen （KI 21）.
文摘In the systematical study on moving cupping method by combination of the clinical practice, the time, speed and strength of moving cupping method are quantified. 15 basic manual techniques of moving cupping methods have been summarized and 10 clinical application protocols have been recommended. In accordance with acupuncture theory, the concept of ＂three-layer moving cupping method＂ has been submitted, in the knowledge that different manual techniques, different protocols in the clinical application can produce different therapeutic effects of different therapies like warming moxibustion, cupping method, scratching method, massage and herbal therapy.
