Comparison of the two recently identified genome sequences has revealed that, of the～1500 genes, some 60 % can be assigned a predicted function, while another 20 % have homologues of unknown identity. The remainder h...Comparison of the two recently identified genome sequences has revealed that, of the～1500 genes, some 60 % can be assigned a predicted function, while another 20 % have homologues of unknown identity. The remainder has no currently identified homologues. Of singular importance is the 'pathogenicity island' of which the cagA-gene is a marker. The vacA-gene is outside the pathogenicity island and is a true cytotoxin. The cag pathogenicity island encodes proteins associated with cell signaling and secretion systems for delivery of virulence factors to target cells. Certaingenotypes, particularly the cag-A positive,展开更多
The global prospects for gastroenterology are excellent. The subspecialty involves the largest area of body surface, the largest endocrine organ, the largest neuronal organ (with 200 million neurones), and the largest...The global prospects for gastroenterology are excellent. The subspecialty involves the largest area of body surface, the largest endocrine organ, the largest neuronal organ (with 200 million neurones), and the largest immune organ (with 50 % of all lymphocytes); it includes by far the largest number of diseases, many still unexplored, and the largest oncological patient load. Gastroenterology/hepatology lies at the cross-roads between internal medical and surgical specialties.展开更多
文摘Comparison of the two recently identified genome sequences has revealed that, of the～1500 genes, some 60 % can be assigned a predicted function, while another 20 % have homologues of unknown identity. The remainder has no currently identified homologues. Of singular importance is the 'pathogenicity island' of which the cagA-gene is a marker. The vacA-gene is outside the pathogenicity island and is a true cytotoxin. The cag pathogenicity island encodes proteins associated with cell signaling and secretion systems for delivery of virulence factors to target cells. Certaingenotypes, particularly the cag-A positive,
文摘The global prospects for gastroenterology are excellent. The subspecialty involves the largest area of body surface, the largest endocrine organ, the largest neuronal organ (with 200 million neurones), and the largest immune organ (with 50 % of all lymphocytes); it includes by far the largest number of diseases, many still unexplored, and the largest oncological patient load. Gastroenterology/hepatology lies at the cross-roads between internal medical and surgical specialties.
