BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social lives.However,these survivors encounter significant challenges during their...BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social lives.However,these survivors encounter significant challenges during their RTW process.Hence,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC survivors.AIM To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW outcomes.METHODS A cross-sectional investigation was adopted in this study.From September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in Chongqing.The investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and FT.To analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were used.RESULTS A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 days.Cox regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further improvement.Elevated levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC survivors.Health professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.展开更多
We give a new result on the construction of K-frame generators for unitary systems by using the pseudo-inverses of involved operators,which provides an improvement to one known result on this topic.We also introduce t...We give a new result on the construction of K-frame generators for unitary systems by using the pseudo-inverses of involved operators,which provides an improvement to one known result on this topic.We also introduce the concept of K-woven generators for unitary systems,by means of which we investigate the weaving properties of K-frame generators for unitary systems.展开更多
The recognition and transformation of learning outcomes is a key step in building a lifelong learning pathway to meet the personalized and diverse learning and development needs of individuals.In response to the probl...The recognition and transformation of learning outcomes is a key step in building a lifelong learning pathway to meet the personalized and diverse learning and development needs of individuals.In response to the problems of incomplete systems,complex processes,and inadequate quality monitoring in the recognition and conversion of learning outcomes at Guangdong Polytechnic of Science and Technology,suggestions are proposed to optimize management methods,standardize the process of recognition and conversion of learning outcomes,build an information platform for recognition and conversion of learning outcomes,and rely on vocational education groups to continuously standardize and orderly carry out recognition and conversion of learning outcomes.展开更多
Metal nanoclusters(MNCs)possess distinct chemical properties due to their diverse electronic structures.As a class of promising model catalysts,it is of importance to explore the relationship between their structures ...Metal nanoclusters(MNCs)possess distinct chemical properties due to their diverse electronic structures.As a class of promising model catalysts,it is of importance to explore the relationship between their structures and properties.However,it is still challenging to get highly active and stable MNCs as surface ligands can hinder their activities,while a complete lack of surface ligand protection can lead to instability.To address this concern,here a series of Pd_(6)nanoclusters(NCs)with varying ligand amounts were synthesized by using Pd_(6)(SC_(6)(C_(2))H_(17))_(12)as precursor and single-walled carbon nanotube(s-CNT)as carrier through treating the composite at different temperatures and times.展开更多
The combination and application of information technology and higher education have led to changes in the form and mode of teaching management in higher education,promoting the continuous deepening of digital transfor...The combination and application of information technology and higher education have led to changes in the form and mode of teaching management in higher education,promoting the continuous deepening of digital transformation in higher education.This paper discusses higher education management innovation triggered by digital technology and the new appearance of digital university governance,digital evaluation management,and internal governance of higher education.From the perspective of forging new forms,models,and paths of digital management through digital technology,this paper focuses on analyzing the reshaping of management systems by digitalization in higher education.The promotion and inspiration of digitalization on management system reform are provided,including typical features brought about,new paths opened up,and new advantages shaped.It is emphasized that the establishment of digital management system needs to rely on the systematic integration of multiple aspects.Finally,the challenges and solutions faced by the digital management system are deeply analyzed from the aspects of collaborative management and services,management process interoperability,evaluation and trust protection,and personnel digital literacy.Digital technology drives the transformation of higher education management system,resulting in new forms,models,paths,and methods of networked and digital management based on intelligent analysis and processing of educational and teaching data and promoting higher education management toward digital governance.The comprehensive establishment of a digital management system will unleash strong potential for universities to better fulfill their functions,and the high-quality development of higher education will be more solid and powerful.展开更多
Objective To identify the key features of facial and tongue images associated with anemia in female populations,establish anemia risk-screening models,and evaluate their performance.Methods A total of 533 female parti...Objective To identify the key features of facial and tongue images associated with anemia in female populations,establish anemia risk-screening models,and evaluate their performance.Methods A total of 533 female participants(anemic and healthy)were recruited from Shuguang Hospital.Facial and tongue images were collected using the TFDA-1 tongue and face diagnosis instrument.Color and texture features from various parts of facial and tongue images were extracted using Face Diagnosis Analysis System(FDAS)and Tongue Diagnosis Analysis System version 2.0(TDAS v2.0).Least Absolute Shrinkage and Selection Operator(LASSO)regression was used for feature selection.Ten machine learning models and one deep learning model(ResNet50V2+Conv1D)were developed and evaluated.Results Anemic women showed lower a-values,higher L-and b-values across all age groups.Texture features analysis showed that women aged 30–39 with anemia had higher angular second moment(ASM)and lower entropy(ENT)values in facial images,while those aged 40–49 had lower contrast(CON),ENT,and MEAN values in tongue images but higher ASM.Anemic women exhibited age-related trends similar to healthy women,with decreasing L-values and increasing a-,b-,and ASM-values.LASSO identified 19 key features from 62.Among classifiers,the Artificial Neural Network(ANN)model achieved the best performance[area under the curve(AUC):0.849,accuracy:0.781].The ResNet50V2 model achieved comparable results[AUC:0.846,accuracy:0.818].Conclusion Differences in facial and tongue images suggest that color and texture features can serve as potential TCM phenotype and auxiliary diagnostic indicators for female anemia.展开更多
This research investigates the bending response of folded multi-celled tubes(FMTs)fabricated by folded metal sheets.A three-point bending test for FMTs with circular and square sections is designed and introduced.The ...This research investigates the bending response of folded multi-celled tubes(FMTs)fabricated by folded metal sheets.A three-point bending test for FMTs with circular and square sections is designed and introduced.The base numerical models are correlated with physical experiments and a static crashworthiness analysis of six FMT configurations to assess their energy absorption characteristics.The influences of thickness,sectional shape,and load direction on the bending response are studied.Results indicate that increasing the thickness of the tube and radian of the inner tube enhances the crashworthiness performance of FMT,yielding a 20.50%increase in mean crushing force,a 55.53%increase in specific energy absorption,and an 18.05%decrease in peak crushing force compared to traditional multi-celled tubes(TMTs).A theoretical analysis of the specific energy absorption indicates that FMTs outperform TMTs,particularly when the peak crushing force is prominent.This study highlights the innovative and practical potential of FMTs to improve the crashworthiness of thin-walled structures.展开更多
By analyzing the structure and academic characteristics of early Western Han medical texts such as Prescriptions for Fifty-Two Diseases(Wu Shi Er Bing Fang)and Prescriptions for Health Preservation(Yang Sheng Fang),an...By analyzing the structure and academic characteristics of early Western Han medical texts such as Prescriptions for Fifty-Two Diseases(Wu Shi Er Bing Fang)and Prescriptions for Health Preservation(Yang Sheng Fang),and considering the development of philosophical thinking during the pre-Qin and Han periods,this study summarizes how Zhongjing Zhang’s Treatise on Cold Damage and Miscellaneous Diseases(Shang Han Za Bing Lun)inherited pre-Qin and Han philosophical thought while further integrating Daoist“natural law”cosmology,Confucian“benevolence”social ethics,and the“isomorphic unity of heaven and humanity”medical theory in Yellow Emperor’s Inner Classic(Huang Di Nei Jing).It proposes health preservation concepts encompassing heaven-human,body-spirit,and benevolence perspectives,along with dietary hygiene,representing the medical embodiment of pre-Han“virtue cultivation”and“body nurturing”life philosophies that profoundly influenced subsequent traditional Chinese medicine health preservation theory and practice.展开更多
Bistorta vivipara is a facultative reproductive plant capable of asexual reproduction through underground rhizomes and bulbils,as well as sexual reproduction via seeds.The phenomenon of vegetative organ vivipary is a ...Bistorta vivipara is a facultative reproductive plant capable of asexual reproduction through underground rhizomes and bulbils,as well as sexual reproduction via seeds.The phenomenon of vegetative organ vivipary is a complex biological process regulated by a network of genes.However,the developmental mechanism regulating bulbil vivipary in B.vivipara remains largely unexplored.This study investigated different developmental stages of B.vivipara using RNA sequencing and transcriptome analysis.Approximately 438 million high-quality reads were generated,with over 61.65%of the data mapped to the de novo transcriptome sequence.A total of 154,813 reads were matched in at least one public database,and 49,731 genes were differentially expressed across developmental stages.Functional analysis revealed significant enrichment of these genes in phenylpropanoid biosynthesis,plant hormone signal transduction,protein processing,starch and sucrose metabolism,and plant-pathogen interaction.Ninety-four genes involved in phytohormones,plant pigments,enzymes,and transcription factors were identified as potential candidates for inducing vegetative organ vivipary.These differentially expressed genes(DEGs),detected through comparative transcriptome analysis,may serve as candidate genes for bulbil vivipary in B.vivipara,establishing a foundation for future studies on the molecular mechanisms underlying vegetative organ vivipary.展开更多
BACKGROUND Although thymopoietin(TMPO)has been elucidated to be overexpressed in cancers,its underlying mechanisms are not yet fully understood.AIM To investigate the expression and clinical significance of TMPO in pa...BACKGROUND Although thymopoietin(TMPO)has been elucidated to be overexpressed in cancers,its underlying mechanisms are not yet fully understood.AIM To investigate the expression and clinical significance of TMPO in papillary thyroid carcinoma(PTC).METHODS Databases such as Gene Expression Omnibus,The Cancer Genome Atlas Proand summary receiver operating characteristic curves were plotted to evaluate diagnostic performance.A Gene Set Enrichment Analysis enrichment analysis was conducted to identify TMPO-related signaling pathways.A protein interaction network was constructed to identify hub genes.The impact of TMPO on PTC cell proliferation and the effects of its knockout were analyzed using clustered regularly interspaced short palindromic repeats(CRISPR)knockout screening and the Cancer Cell Line Encyclopedia database.RESULTS The TMPO protein was significantly overexpressed in PTC tissues,primarily localized in the cytoplasm and nuclear membrane.The mRNA level analysis showed mild overexpression of TMPO in PTC tissues,with a certain discriminatory value(area under the curve=0.66).TMPO may promote cancer through involvement in cell adhesion,focal adhesion,leukocyte migration,and multiple cancer-related signaling pathways.Additionally,CRISPR gene knockout experiments confirmed that TMPO knockout significantly inhibited the proliferation of PTC cell lines,indicating its important role in tumor growth.CONCLUSION TMPO is overexpressed in PTC and may serve as a therapeutic target and molecular biomarker for PTC.展开更多
OBJECTIVE:To evaluate the available evidence from randomized controlled trials(RCTs)of moxibustion alone for lumbar disc herniation(LDH)treatment.METHODS:A systematic search of 10 databases(until August 30,2021)was us...OBJECTIVE:To evaluate the available evidence from randomized controlled trials(RCTs)of moxibustion alone for lumbar disc herniation(LDH)treatment.METHODS:A systematic search of 10 databases(until August 30,2021)was used to identify studies that reported the response rate,visual analogue scale(VAS)score,Japanese Orthopedic Association(JOA)score,and Oswestry Disability Index(ODI)score.Study selection and data extraction were independently performed by two reviewers.Cochrane criteria for risk of bias were used to assess the methodological quality of the trials.The Grading of Recommendations Assessment,Development,and Evaluation Methodology(GRADE)were also used to test the quality of the result evidence.RESULTS:Nineteen RCTs,including 1888 patients,met the inclusion criteria.Five studies showed no difference between moxibustion and acupuncture on response rate[risk ratio(RR)=1.07,95%CI(0.98,1.16),P=0.11].Meanwhile,six studies suggested that there is no significant difference between moxibustion and acupuncture on VAS score[mean difference(MD)=-0.43,95%CI(-0.91,0.05),P=0.08].Eight studies implied that there is no significant difference between moxibustion and acupuncture on JOA score[MD=0.84,95%CI(-1.27,2.96),P=0.44].Two studies indicated that moxibustion may have equivalent effects for treating LDH in the VAS score in comparison with drug therapy[MD=-1.16,95%CI(-2.63,0.31),P=0.12].The evidence level of results was determined to be very low to low.CONCLUSIONS:Based on the existing evidence,moxibustion may not be suitable for treating LDH alone,but it may be applied as an adjuvant treatment.Furthermore,well-designed RCTs with high quality and larger samples are still needed to evaluate the efficacy and safety of moxibustion alone for LDH treatment.展开更多
Thymosin alpha 1 is a peptide naturally occurring in the thymus that has long been recognized for modifying,enhancing,and restoring immune function.Thymosin alpha 1 has been utilized in the treatment of immunocompromi...Thymosin alpha 1 is a peptide naturally occurring in the thymus that has long been recognized for modifying,enhancing,and restoring immune function.Thymosin alpha 1 has been utilized in the treatment of immunocompromised states and malignancies,as an enhancer of vaccine response,and as a means of curbing morbidity and mortality in sepsis and numerous infections.Studies have postulated that thymosin alpha 1 could help improve the outcome in severely ill corona virus disease 2019 patients by repairing damage caused by overactivation of lymphocytic immunity and how thymosin alpha 1 could prevent the excessive activation of T cells.In this review,we discuss key literature on the background knowledge and current clinical uses of thymosin alpha 1.Considering the known biochemical properties including antibacterial and antiviral properties,timehonored applications,and the new promising findings regarding the use of thymosin,we believe that thymosin alpha 1 deserves further investigation into its antiviral properties and possible repurposing as a treatment against severe acute respiratory syndrome coronavirus-2.展开更多
Objective To assess the association of socioeconomic status with the burden of cataract blindness in terms of year lived with disability(YLD) rates and to determine whether ultraviolet radiation(UVR) levels modify the...Objective To assess the association of socioeconomic status with the burden of cataract blindness in terms of year lived with disability(YLD) rates and to determine whether ultraviolet radiation(UVR) levels modify the effect of socioeconomic status on this health burden.Methods National and subnational age-standardized YLD rates associated with cataract-related blindness were derived from the Global Burden of Disease(GBD) study 2017. The human development index(HDI) from the Human Development Report was used as a measure of socioeconomic status.Estimated ground-level UVR exposure was obtained from the Ozone Monitoring Instrument(OMI)dataset of the National Aeronautics and Space Administration(NASA).Results Across 185 countries, socioeconomic status was inversely associated with the burden of cataract blindness. Countries with a very high HDI had an 84% lower age-standardized YLD rate [95%confidence interval(CI): 60%–93%, P < 0.001] than countries with a low HDI;for high-HDI countries, the proportion was 76%(95% CI: 53%–88%, P < 0.001), and for medium-HDI countries, the proportion was48%(95% CI: 15%–68%, P = 0.010;P for trend < 0.001). The interaction analysis showed that UVR exposure played an interactive role in the association between socioeconomic status and cataract blindness burden(P value for interaction = 0.047).Conclusion Long-term high-UVR exposure amplifies the association of poor socioeconomic status with the burden of cataract-related blindness. The findings emphasize the need for strengthening UVR exposure protection interventions in developing countries with high-UVR exposure.展开更多
Recently, a new （2＋1）-dimensional shallow water wave system, the （2＋1）-dlmenslonal displacement shallow water wave system （2DDSWWS）, was constructed by applying the variational principle of the analytic mechan...Recently, a new （2＋1）-dimensional shallow water wave system, the （2＋1）-dlmenslonal displacement shallow water wave system （2DDSWWS）, was constructed by applying the variational principle of the analytic mechanics in the Lagrange coordinates. The disadvantage is that fluid viscidity is not considered in the 2DDSWWS, which is the same as the famous Kadomtsev-Petviashvili equation and Korteweg-de Vries equation. Applying dimensional analysis, we modify the 2DDSWWS and add the term related to the fluid viscidity to the 2DDSWWS. The approximate similarity solutions of the modified 2DDSWWS （M2DDSWWS） is studied and four similarity solutions are obtained. For the perfect fluids, the coefficient of kinematic viscosity is zero, then the M2DDSWWS will degenerate to the 2DDSWWS.展开更多
In the video-based surveillance application, moving shadows can affect the correct localization and detection of moving objects. This paper aims to present a method for shadow detection and suppression used for moving...In the video-based surveillance application, moving shadows can affect the correct localization and detection of moving objects. This paper aims to present a method for shadow detection and suppression used for moving visual object detection. The major novelty of the shadow suppression is the integration of several features including photometric invariant color feature, motion edge feature, and spatial feature etc. By modifying process for false shadow detected, the averaging detection rate of moving object reaches above 90% in the test of Hall-Monitor sequence.展开更多
We compared the activities of functional regions of the brain in the Deqi versus non-Deqi state, as reported by physicians and subjects cludng acupuncture, Twelve healthy volunteers received sham and true needling at ...We compared the activities of functional regions of the brain in the Deqi versus non-Deqi state, as reported by physicians and subjects cludng acupuncture, Twelve healthy volunteers received sham and true needling at the Waiguan （TE5） acupoint. Real-time cerebral functional MRI showed that compared with non-sensation after sham needling, true needling activated Brodmann areas 3, 6, 8, 9, 10, 11, 13, 20, 21, 37, 39, 40, 43, and 47, the head of the caudate nucleus, the parahippocampal gyrus, thalamus and red nucleus. True needling also deactivated Brodmann areas 1,2, 3, 4, 5, 6, 7, 9. 10. 18.24.31.40 and 46.展开更多
The support materials are an important part of catalysts and they are the dispersant,adhesive,and support for other components.In this study,three types of thin films with different structures were used as the precurs...The support materials are an important part of catalysts and they are the dispersant,adhesive,and support for other components.In this study,three types of thin films with different structures were used as the precursor to prepare loading Pd catalysts.The one-step dealloying method was used to prepare a semiconductor nanofiber film(NFF)support material with upward directional growth from the substrate.Pd/NFF and Pd/Ni O/NFF loaded Pd catalysts were prepared using NFF as the support material,and the electrochemical catalytic properties for ethanol oxidation in alkaline media were studied.Cyclic votammetry showed that the NFF support material effectively inhibited agglomeration of palladium,increased the number of active sites of Pd,and improved the electrocatalytic properties of Pd for ethanol oxidation.In addition,the Pd/Ni O/NFF loaded Pd catalyst obtained by modification with nickel oxide significantly improved the electrocatalytic performance for ethanol oxidation compared with the Pd/NFF loaded Pd catalyst.These results show that Ni O is conductive to absorption of oxygen-containing groups on the surface of the catalyst and can further improve the electrocatalytic ability of Pd for ethanol oxidation.All of the above results demonstrate that the support material prepared by the dealloying method has application prospects in load-type catalysts.展开更多
In machine learning,randomness is a crucial factor in the success of ensemble learning,and it can be injected into tree-based ensembles by rotating the feature space.However,it is a common practice to rotate the featu...In machine learning,randomness is a crucial factor in the success of ensemble learning,and it can be injected into tree-based ensembles by rotating the feature space.However,it is a common practice to rotate the feature space randomly.Thus,a large number of trees are required to ensure the performance of the ensemble model.This random rotation method is theoretically feasible,but it requires massive computing resources,potentially restricting its applications.A multimodal genetic algorithm based rotation forest(MGARF)algorithm is proposed in this paper to solve this problem.It is a tree-based ensemble learning algorithm for classification,taking advantage of the characteristic of trees to inject randomness by feature rotation.However,this algorithm attempts to select a subset of more diverse and accurate base learners using the multimodal optimization method.The classification accuracy of the proposed MGARF algorithm was evaluated by comparing it with the original random forest and random rotation ensemble methods on 23 UCI classification datasets.Experimental results show that the MGARF method outperforms the other methods,and the number of base learners in MGARF models is much fewer.展开更多
In the course of vehicle license plate （VLP） automatic recognition, tilt correction is a very crucial process. According to Karhunen-Loeve （K-L） transformation, the coordinates of characters in the image are arran...In the course of vehicle license plate （VLP） automatic recognition, tilt correction is a very crucial process. According to Karhunen-Loeve （K-L） transformation, the coordinates of characters in the image are arranged into a two-dimensional covariance matrix, on the basis of which the centered process is carried out. Then, the eigenvector and the rotation angle α are computed in turn. The whole image is rotated by -α. Thus, image horizontal tilt correction is performed. In the vertical tilt correction process, three correction methods, which are K-L transformation method, the line fitting method based on K -means clustering （LFMBKC）, and the line fitting based on least squares （LFMBLS）, are put forward to compute the vertical tilt angle θ. After shear transformation （ST） is imposed on the rotated image, the final correction image is obtained. The experimental results verify that this proposed method can be easily implemented, and can quickly and accurately get the tilt angle. It provides a new effective way for the VLP image tilt correction as well.展开更多
The development of Internet technology has brought convenience to the development of education and teaching,and has also changed the traditional methods and means of education and teaching. The construction of an inte...The development of Internet technology has brought convenience to the development of education and teaching,and has also changed the traditional methods and means of education and teaching. The construction of an integrated network teaching platform based on Internet technology brings new opportunities for the development of higher education. Taking the construction of the integrated network teaching platform of Northwest A&F University as an example,the current situation and existing problems in the construction of the integrated network teaching platform of the Northwest A&F University are explained. By proposing the promotion strategies for the application of the integrated network teaching platform,the construction of the integrated network teaching platform is improved,thereby facilitating the online and offline mixed teaching and further promoting the improvement of teaching level and teaching effect.展开更多
基金Supported by the Chongqing Medical University Program for Youth Innovation in Future Medicine,No.W0019Chongqing Municipal Education Commission’s 14th Five-Year Key Discipline Support Project,No.20240101 and No.20240102。
文摘BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social lives.However,these survivors encounter significant challenges during their RTW process.Hence,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC survivors.AIM To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW outcomes.METHODS A cross-sectional investigation was adopted in this study.From September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in Chongqing.The investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and FT.To analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were used.RESULTS A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 days.Cox regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further improvement.Elevated levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC survivors.Health professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.
基金Supported by NSFC(Nos.12361028,11761057)Science Foundation of Jiangxi Education Department(Nos.GJJ202302,GJJ202303,GJJ202319).
文摘We give a new result on the construction of K-frame generators for unitary systems by using the pseudo-inverses of involved operators,which provides an improvement to one known result on this topic.We also introduce the concept of K-woven generators for unitary systems,by means of which we investigate the weaving properties of K-frame generators for unitary systems.
基金Guangdong Provincial Education Science Planning Project:Strategic Research on the Implementation Path of“Optimizing the Positioning of Vocational Education Types”in Guangdong Province in the New Era(2023GXJK738)Research and Practice Project on Education and Teaching Reform:Exploration of Collaborative Innovation and Development of Curriculum,Resources,and Textbooks in Higher Vocational Colleges。
文摘The recognition and transformation of learning outcomes is a key step in building a lifelong learning pathway to meet the personalized and diverse learning and development needs of individuals.In response to the problems of incomplete systems,complex processes,and inadequate quality monitoring in the recognition and conversion of learning outcomes at Guangdong Polytechnic of Science and Technology,suggestions are proposed to optimize management methods,standardize the process of recognition and conversion of learning outcomes,build an information platform for recognition and conversion of learning outcomes,and rely on vocational education groups to continuously standardize and orderly carry out recognition and conversion of learning outcomes.
基金financially supported by the Natural Science Foundation of Guangxi,China(Nos.2019GXNSFGA245003 and 2021GXNSFBA220058)the National Natural Science Foundation of China(Nos.22272036 and 22362008)+2 种基金Guangxi Technology Base and Talent Subject,China(GUIKE AD23026272)Guangxi Normal University Research Grant,China(No.2022TD)Innovation Project of Guangxi Graduate Education(No.XYCSR2023018)。
文摘Metal nanoclusters(MNCs)possess distinct chemical properties due to their diverse electronic structures.As a class of promising model catalysts,it is of importance to explore the relationship between their structures and properties.However,it is still challenging to get highly active and stable MNCs as surface ligands can hinder their activities,while a complete lack of surface ligand protection can lead to instability.To address this concern,here a series of Pd_(6)nanoclusters(NCs)with varying ligand amounts were synthesized by using Pd_(6)(SC_(6)(C_(2))H_(17))_(12)as precursor and single-walled carbon nanotube(s-CNT)as carrier through treating the composite at different temperatures and times.
基金supported by the Project of the 2023 Shandong Province Higher Education Curriculum Ideological and Political Education Reform Research Project“Value Connotation,Intrinsic Logic,and Method Path:Student-centered College Curriculum Ideological and Political Integration‘Salt’in Course Teaching”(SZ2023003)Shandong Provincial Department of Education Key Teaching and Research Project“Ideological and Political Guidance,Goal Orientation,and Multidimensional Integration—Research and Practice of Embedded System Series Curriculum Teaching for New Engineering Majors”(Z2022232)+2 种基金2023 Harbin Institute of Technology(Weihai)Education and Teaching Reform Research Project“Connotation Elements,Related Logic,and Core Measures:Basic Paradigm of Curriculum Construction and Classroom Teaching Reform”(2023MSZZ01)the Key Teaching and Research Project of Shandong Provincial Department of Education,“I+IV”Mentor System—Exploration and Practice of Innovative Talents Training Model for Intelligent Vehicle Engineering New Engineering(Z2023002)the 2024 Harbin Institute of Technology(Weihai)Experimental Teaching and Teaching Laboratory Construction Research Project“Online and Offline Mixing,Virtual-practical Operation Integration,Industrial Technology Guidance—Research and Exploration of New Form Experimental Teaching of Computer Composition Principles”(2024SYZZ03)。
文摘The combination and application of information technology and higher education have led to changes in the form and mode of teaching management in higher education,promoting the continuous deepening of digital transformation in higher education.This paper discusses higher education management innovation triggered by digital technology and the new appearance of digital university governance,digital evaluation management,and internal governance of higher education.From the perspective of forging new forms,models,and paths of digital management through digital technology,this paper focuses on analyzing the reshaping of management systems by digitalization in higher education.The promotion and inspiration of digitalization on management system reform are provided,including typical features brought about,new paths opened up,and new advantages shaped.It is emphasized that the establishment of digital management system needs to rely on the systematic integration of multiple aspects.Finally,the challenges and solutions faced by the digital management system are deeply analyzed from the aspects of collaborative management and services,management process interoperability,evaluation and trust protection,and personnel digital literacy.Digital technology drives the transformation of higher education management system,resulting in new forms,models,paths,and methods of networked and digital management based on intelligent analysis and processing of educational and teaching data and promoting higher education management toward digital governance.The comprehensive establishment of a digital management system will unleash strong potential for universities to better fulfill their functions,and the high-quality development of higher education will be more solid and powerful.
基金Funding This research was funded by funding from the National Natural Science Foundation of China(No.82305090,No.82104738)Key Discipline Construction Project of High-level Traditional Chinese Medicine of the National Administration of Traditional Chinese Medicine-Traditional Chinese Medical Diagnostics(ZYYZDXK-2023069)+5 种基金Shanghai Municipal Health Commission Project(No.20234Y0168,No.2024QN018)Shanghai Science and Technology Commission Rising Star Cultivation Project(No.22YF1448900)Capacity Building of Local Colleges and Universities under the Shanghai Municipal Science and Technology Commission(21010504400)General Program of China Postdoctoral Science Foundation(2023M732337)Shanghai“Super Postdoctoral”Incentive Plan(2022509)Science and Technology Development Project of Shanghai University of Traditional Chinese Medicine(23KFL005).
文摘Objective To identify the key features of facial and tongue images associated with anemia in female populations,establish anemia risk-screening models,and evaluate their performance.Methods A total of 533 female participants(anemic and healthy)were recruited from Shuguang Hospital.Facial and tongue images were collected using the TFDA-1 tongue and face diagnosis instrument.Color and texture features from various parts of facial and tongue images were extracted using Face Diagnosis Analysis System(FDAS)and Tongue Diagnosis Analysis System version 2.0(TDAS v2.0).Least Absolute Shrinkage and Selection Operator(LASSO)regression was used for feature selection.Ten machine learning models and one deep learning model(ResNet50V2+Conv1D)were developed and evaluated.Results Anemic women showed lower a-values,higher L-and b-values across all age groups.Texture features analysis showed that women aged 30–39 with anemia had higher angular second moment(ASM)and lower entropy(ENT)values in facial images,while those aged 40–49 had lower contrast(CON),ENT,and MEAN values in tongue images but higher ASM.Anemic women exhibited age-related trends similar to healthy women,with decreasing L-values and increasing a-,b-,and ASM-values.LASSO identified 19 key features from 62.Among classifiers,the Artificial Neural Network(ANN)model achieved the best performance[area under the curve(AUC):0.849,accuracy:0.781].The ResNet50V2 model achieved comparable results[AUC:0.846,accuracy:0.818].Conclusion Differences in facial and tongue images suggest that color and texture features can serve as potential TCM phenotype and auxiliary diagnostic indicators for female anemia.
基金supported by the National Natural Science Foundation of China(Grant No.52475277)2022 Guangxi University Young and Middle-aged Teachers’Basic Research Ability Improvement Project(Grant No.2022KY0781)Scientific Research Funds of Guilin University of Aerospace Technology(Grant No.XJ22KT29).
文摘This research investigates the bending response of folded multi-celled tubes(FMTs)fabricated by folded metal sheets.A three-point bending test for FMTs with circular and square sections is designed and introduced.The base numerical models are correlated with physical experiments and a static crashworthiness analysis of six FMT configurations to assess their energy absorption characteristics.The influences of thickness,sectional shape,and load direction on the bending response are studied.Results indicate that increasing the thickness of the tube and radian of the inner tube enhances the crashworthiness performance of FMT,yielding a 20.50%increase in mean crushing force,a 55.53%increase in specific energy absorption,and an 18.05%decrease in peak crushing force compared to traditional multi-celled tubes(TMTs).A theoretical analysis of the specific energy absorption indicates that FMTs outperform TMTs,particularly when the peak crushing force is prominent.This study highlights the innovative and practical potential of FMTs to improve the crashworthiness of thin-walled structures.
基金supported by the Henan Provincial Traditional Chinese Medicine Culture and Management Research Project(TCM2022036)Henan Provincial Traditional Chinese Medicine Culture Publication Funding Special Project(TCMCB2023016)+3 种基金Henan University of Chinese Medicine Research Seedling Project(MP2023-29)National Administration of Traditional Chinese Medicine Science and Technology Project(GZY-KJS-2022-043-1)Henan Culture-Promoting Project Cultural Research Special Project(2022XWH231)National Administration of Traditional Chinese Medicine Science and Technology Project(GZY-KJS-2022-037).
文摘By analyzing the structure and academic characteristics of early Western Han medical texts such as Prescriptions for Fifty-Two Diseases(Wu Shi Er Bing Fang)and Prescriptions for Health Preservation(Yang Sheng Fang),and considering the development of philosophical thinking during the pre-Qin and Han periods,this study summarizes how Zhongjing Zhang’s Treatise on Cold Damage and Miscellaneous Diseases(Shang Han Za Bing Lun)inherited pre-Qin and Han philosophical thought while further integrating Daoist“natural law”cosmology,Confucian“benevolence”social ethics,and the“isomorphic unity of heaven and humanity”medical theory in Yellow Emperor’s Inner Classic(Huang Di Nei Jing).It proposes health preservation concepts encompassing heaven-human,body-spirit,and benevolence perspectives,along with dietary hygiene,representing the medical embodiment of pre-Han“virtue cultivation”and“body nurturing”life philosophies that profoundly influenced subsequent traditional Chinese medicine health preservation theory and practice.
基金supported by the National Natural Science Foundation of China(31960222)the Qinghai Provincial Major Science and Technology Special Funds(2023-NK-A3).
文摘Bistorta vivipara is a facultative reproductive plant capable of asexual reproduction through underground rhizomes and bulbils,as well as sexual reproduction via seeds.The phenomenon of vegetative organ vivipary is a complex biological process regulated by a network of genes.However,the developmental mechanism regulating bulbil vivipary in B.vivipara remains largely unexplored.This study investigated different developmental stages of B.vivipara using RNA sequencing and transcriptome analysis.Approximately 438 million high-quality reads were generated,with over 61.65%of the data mapped to the de novo transcriptome sequence.A total of 154,813 reads were matched in at least one public database,and 49,731 genes were differentially expressed across developmental stages.Functional analysis revealed significant enrichment of these genes in phenylpropanoid biosynthesis,plant hormone signal transduction,protein processing,starch and sucrose metabolism,and plant-pathogen interaction.Ninety-four genes involved in phytohormones,plant pigments,enzymes,and transcription factors were identified as potential candidates for inducing vegetative organ vivipary.These differentially expressed genes(DEGs),detected through comparative transcriptome analysis,may serve as candidate genes for bulbil vivipary in B.vivipara,establishing a foundation for future studies on the molecular mechanisms underlying vegetative organ vivipary.
基金Supported by Guangxi Zhuang Autonomous Region Health Commission Scientific Research Project,No.Z-A20220521Guangxi Higher Education Undergraduate Teaching Reform Project,No.2022JGA147The National College Students’Innovation and Entrepreneurship Training Program,No.202310598042.
文摘BACKGROUND Although thymopoietin(TMPO)has been elucidated to be overexpressed in cancers,its underlying mechanisms are not yet fully understood.AIM To investigate the expression and clinical significance of TMPO in papillary thyroid carcinoma(PTC).METHODS Databases such as Gene Expression Omnibus,The Cancer Genome Atlas Proand summary receiver operating characteristic curves were plotted to evaluate diagnostic performance.A Gene Set Enrichment Analysis enrichment analysis was conducted to identify TMPO-related signaling pathways.A protein interaction network was constructed to identify hub genes.The impact of TMPO on PTC cell proliferation and the effects of its knockout were analyzed using clustered regularly interspaced short palindromic repeats(CRISPR)knockout screening and the Cancer Cell Line Encyclopedia database.RESULTS The TMPO protein was significantly overexpressed in PTC tissues,primarily localized in the cytoplasm and nuclear membrane.The mRNA level analysis showed mild overexpression of TMPO in PTC tissues,with a certain discriminatory value(area under the curve=0.66).TMPO may promote cancer through involvement in cell adhesion,focal adhesion,leukocyte migration,and multiple cancer-related signaling pathways.Additionally,CRISPR gene knockout experiments confirmed that TMPO knockout significantly inhibited the proliferation of PTC cell lines,indicating its important role in tumor growth.CONCLUSION TMPO is overexpressed in PTC and may serve as a therapeutic target and molecular biomarker for PTC.
基金Supported by the National Natural Science Foundation of China:Study on Multi-target Regulation Mechanism of Moxibustion on Rheumatoid Arthritis Based on Signal Pathway of Lipid Metabolism Network(No.81774383)Study on the Multi target Effect Mechanism of Moxibustion Intervention on Ankylosing Spondylitis Based on Metabolic Proteomics and System Bioinformatics Cross linking Analysis between Genomics(No.81904274)Supported by the"Research and Innovation Plan for Postgraduates in Jiangsu Province"of the Nanjing University of Chinese Medicine:Clinical Experimental Study on the Effect of Different Moxibustion Duration on Lumbar Disc Herniation(SJCX20_0524),Clinical Study on the Treatment of Lumbar Disc Herniation with Thunder Fire Moxibustion and Common Moxibustion(SJCX20_0525)。
文摘OBJECTIVE:To evaluate the available evidence from randomized controlled trials(RCTs)of moxibustion alone for lumbar disc herniation(LDH)treatment.METHODS:A systematic search of 10 databases(until August 30,2021)was used to identify studies that reported the response rate,visual analogue scale(VAS)score,Japanese Orthopedic Association(JOA)score,and Oswestry Disability Index(ODI)score.Study selection and data extraction were independently performed by two reviewers.Cochrane criteria for risk of bias were used to assess the methodological quality of the trials.The Grading of Recommendations Assessment,Development,and Evaluation Methodology(GRADE)were also used to test the quality of the result evidence.RESULTS:Nineteen RCTs,including 1888 patients,met the inclusion criteria.Five studies showed no difference between moxibustion and acupuncture on response rate[risk ratio(RR)=1.07,95%CI(0.98,1.16),P=0.11].Meanwhile,six studies suggested that there is no significant difference between moxibustion and acupuncture on VAS score[mean difference(MD)=-0.43,95%CI(-0.91,0.05),P=0.08].Eight studies implied that there is no significant difference between moxibustion and acupuncture on JOA score[MD=0.84,95%CI(-1.27,2.96),P=0.44].Two studies indicated that moxibustion may have equivalent effects for treating LDH in the VAS score in comparison with drug therapy[MD=-1.16,95%CI(-2.63,0.31),P=0.12].The evidence level of results was determined to be very low to low.CONCLUSIONS:Based on the existing evidence,moxibustion may not be suitable for treating LDH alone,but it may be applied as an adjuvant treatment.Furthermore,well-designed RCTs with high quality and larger samples are still needed to evaluate the efficacy and safety of moxibustion alone for LDH treatment.
文摘Thymosin alpha 1 is a peptide naturally occurring in the thymus that has long been recognized for modifying,enhancing,and restoring immune function.Thymosin alpha 1 has been utilized in the treatment of immunocompromised states and malignancies,as an enhancer of vaccine response,and as a means of curbing morbidity and mortality in sepsis and numerous infections.Studies have postulated that thymosin alpha 1 could help improve the outcome in severely ill corona virus disease 2019 patients by repairing damage caused by overactivation of lymphocytic immunity and how thymosin alpha 1 could prevent the excessive activation of T cells.In this review,we discuss key literature on the background knowledge and current clinical uses of thymosin alpha 1.Considering the known biochemical properties including antibacterial and antiviral properties,timehonored applications,and the new promising findings regarding the use of thymosin,we believe that thymosin alpha 1 deserves further investigation into its antiviral properties and possible repurposing as a treatment against severe acute respiratory syndrome coronavirus-2.
基金supported by a grant from the National Natural Science Foundation of China No. 81673133 and No.81273034。
文摘Objective To assess the association of socioeconomic status with the burden of cataract blindness in terms of year lived with disability(YLD) rates and to determine whether ultraviolet radiation(UVR) levels modify the effect of socioeconomic status on this health burden.Methods National and subnational age-standardized YLD rates associated with cataract-related blindness were derived from the Global Burden of Disease(GBD) study 2017. The human development index(HDI) from the Human Development Report was used as a measure of socioeconomic status.Estimated ground-level UVR exposure was obtained from the Ozone Monitoring Instrument(OMI)dataset of the National Aeronautics and Space Administration(NASA).Results Across 185 countries, socioeconomic status was inversely associated with the burden of cataract blindness. Countries with a very high HDI had an 84% lower age-standardized YLD rate [95%confidence interval(CI): 60%–93%, P < 0.001] than countries with a low HDI;for high-HDI countries, the proportion was 76%(95% CI: 53%–88%, P < 0.001), and for medium-HDI countries, the proportion was48%(95% CI: 15%–68%, P = 0.010;P for trend < 0.001). The interaction analysis showed that UVR exposure played an interactive role in the association between socioeconomic status and cataract blindness burden(P value for interaction = 0.047).Conclusion Long-term high-UVR exposure amplifies the association of poor socioeconomic status with the burden of cataract-related blindness. The findings emphasize the need for strengthening UVR exposure protection interventions in developing countries with high-UVR exposure.
基金Project supported by the Natural Science Foundation of Guangdong Province of China (Grant No.10452840301004616)the National Natural Science Foundation of China (Grant No.61001018)the Scientific Research Foundation for the Doctors of University of Electronic Science and Technology of China Zhongshan Institute (Grant No.408YKQ09)
文摘Recently, a new （2＋1）-dimensional shallow water wave system, the （2＋1）-dlmenslonal displacement shallow water wave system （2DDSWWS）, was constructed by applying the variational principle of the analytic mechanics in the Lagrange coordinates. The disadvantage is that fluid viscidity is not considered in the 2DDSWWS, which is the same as the famous Kadomtsev-Petviashvili equation and Korteweg-de Vries equation. Applying dimensional analysis, we modify the 2DDSWWS and add the term related to the fluid viscidity to the 2DDSWWS. The approximate similarity solutions of the modified 2DDSWWS （M2DDSWWS） is studied and four similarity solutions are obtained. For the perfect fluids, the coefficient of kinematic viscosity is zero, then the M2DDSWWS will degenerate to the 2DDSWWS.
文摘In the video-based surveillance application, moving shadows can affect the correct localization and detection of moving objects. This paper aims to present a method for shadow detection and suppression used for moving visual object detection. The major novelty of the shadow suppression is the integration of several features including photometric invariant color feature, motion edge feature, and spatial feature etc. By modifying process for false shadow detected, the averaging detection rate of moving object reaches above 90% in the test of Hall-Monitor sequence.
基金supported by the National Basic Research Program of China (973 Program), No. 2006CB504505,2012CB518504the Third Key Construction Program of"211 Project" of Guangdong Province
文摘We compared the activities of functional regions of the brain in the Deqi versus non-Deqi state, as reported by physicians and subjects cludng acupuncture, Twelve healthy volunteers received sham and true needling at the Waiguan （TE5） acupoint. Real-time cerebral functional MRI showed that compared with non-sensation after sham needling, true needling activated Brodmann areas 3, 6, 8, 9, 10, 11, 13, 20, 21, 37, 39, 40, 43, and 47, the head of the caudate nucleus, the parahippocampal gyrus, thalamus and red nucleus. True needling also deactivated Brodmann areas 1,2, 3, 4, 5, 6, 7, 9. 10. 18.24.31.40 and 46.
基金supported financially by the National Natural Science Foundation of China(No.51801050)the National Key Research and Development Project(No.2016YFB0300500)+1 种基金the Fundamental Research Funds for the Central Universities(No.JZ2019HGBZ0188)the Fundamental Research Funds for the Central Universities(No.JZ2016HGPB0671)。
文摘The support materials are an important part of catalysts and they are the dispersant,adhesive,and support for other components.In this study,three types of thin films with different structures were used as the precursor to prepare loading Pd catalysts.The one-step dealloying method was used to prepare a semiconductor nanofiber film(NFF)support material with upward directional growth from the substrate.Pd/NFF and Pd/Ni O/NFF loaded Pd catalysts were prepared using NFF as the support material,and the electrochemical catalytic properties for ethanol oxidation in alkaline media were studied.Cyclic votammetry showed that the NFF support material effectively inhibited agglomeration of palladium,increased the number of active sites of Pd,and improved the electrocatalytic properties of Pd for ethanol oxidation.In addition,the Pd/Ni O/NFF loaded Pd catalyst obtained by modification with nickel oxide significantly improved the electrocatalytic performance for ethanol oxidation compared with the Pd/NFF loaded Pd catalyst.These results show that Ni O is conductive to absorption of oxygen-containing groups on the surface of the catalyst and can further improve the electrocatalytic ability of Pd for ethanol oxidation.All of the above results demonstrate that the support material prepared by the dealloying method has application prospects in load-type catalysts.
基金Project(61603274)supported by the National Natural Science Foundation of ChinaProject(2017KJ249)supported by the Research Project of Tianjin Municipal Education Commission,China。
文摘In machine learning,randomness is a crucial factor in the success of ensemble learning,and it can be injected into tree-based ensembles by rotating the feature space.However,it is a common practice to rotate the feature space randomly.Thus,a large number of trees are required to ensure the performance of the ensemble model.This random rotation method is theoretically feasible,but it requires massive computing resources,potentially restricting its applications.A multimodal genetic algorithm based rotation forest(MGARF)algorithm is proposed in this paper to solve this problem.It is a tree-based ensemble learning algorithm for classification,taking advantage of the characteristic of trees to inject randomness by feature rotation.However,this algorithm attempts to select a subset of more diverse and accurate base learners using the multimodal optimization method.The classification accuracy of the proposed MGARF algorithm was evaluated by comparing it with the original random forest and random rotation ensemble methods on 23 UCI classification datasets.Experimental results show that the MGARF method outperforms the other methods,and the number of base learners in MGARF models is much fewer.
基金supported by Scientific Research Fund of Hunan Province, PRC (No. 07JJ6141)Scientific Research Fund of Hunan Provincial Education Department, PRC (No. 06C582)
文摘In the course of vehicle license plate （VLP） automatic recognition, tilt correction is a very crucial process. According to Karhunen-Loeve （K-L） transformation, the coordinates of characters in the image are arranged into a two-dimensional covariance matrix, on the basis of which the centered process is carried out. Then, the eigenvector and the rotation angle α are computed in turn. The whole image is rotated by -α. Thus, image horizontal tilt correction is performed. In the vertical tilt correction process, three correction methods, which are K-L transformation method, the line fitting method based on K -means clustering （LFMBKC）, and the line fitting based on least squares （LFMBLS）, are put forward to compute the vertical tilt angle θ. After shear transformation （ST） is imposed on the rotated image, the final correction image is obtained. The experimental results verify that this proposed method can be easily implemented, and can quickly and accurately get the tilt angle. It provides a new effective way for the VLP image tilt correction as well.
文摘The development of Internet technology has brought convenience to the development of education and teaching,and has also changed the traditional methods and means of education and teaching. The construction of an integrated network teaching platform based on Internet technology brings new opportunities for the development of higher education. Taking the construction of the integrated network teaching platform of Northwest A&F University as an example,the current situation and existing problems in the construction of the integrated network teaching platform of the Northwest A&F University are explained. By proposing the promotion strategies for the application of the integrated network teaching platform,the construction of the integrated network teaching platform is improved,thereby facilitating the online and offline mixed teaching and further promoting the improvement of teaching level and teaching effect.
