Change in the information landscape has afforded librarians an opportunity to actively seek new skills,knowledge,and opportunities in order to effectively integrate expertise at the point of need; in particular,librar...Change in the information landscape has afforded librarians an opportunity to actively seek new skills,knowledge,and opportunities in order to effectively integrate expertise at the point of need; in particular,librarians have shifted from being information providers to embedded information creators,integrators,and innovators. Our ability to capitalize on the strengths of our specific institutional environments and respond to information needs is ever more important if we are to remain central to the work of our academic enterprise. This article describes how the University of North Carolina at Chapel Hill ＇ s Health Sciences Library(HSL） has sought opportunities and established successful partnerships that integrate library expertise aligning with the two core strategies of Carolina＇s new strategic framework Blueprint for Next： Of the Public,For the Public,and Innovation Made Fundamental.These efforts have resulted in initiatives that improve access to quality health care and health care information for North Carolinians,accelerate the campus＇ research enterprise,and demonstrate the importance of evidence-based care at UNC and globally. By understanding and identifying the needs of our various stakeholders,we have been able to progress with our understanding of what key problems need to be solved,what interventions need to be developed,and in what ways librarians can integrate expertise around information synthesis and critical thinking so that we are seen as valued partners in our complex academic environment.展开更多
Academic dishonesty is a disturbing issue in higher education that has been worsening over the years, especially with the appearance of the internet and the e-learning education. This new technology exposes students t...Academic dishonesty is a disturbing issue in higher education that has been worsening over the years, especially with the appearance of the internet and the e-learning education. This new technology exposes students to the opportunity of using online bank exams and term papers and increases their tendency to cheat. This study investigates student academic dishonesty in the context of traditional and distance-learning courses in higher education. Data from 1,365 students enrolled in academic institutes in the U.S.A and Israel were surveyed to assess their personality and their willingness to commit various acts of academic misconduct. The findings indicate that in both countries dishonest behaviors are greater in face-to-face courses than in online courses. In addition, both American and Israeli students identified with the personality trait of Agreeableness showed a negative correlation with academic dishonesty. Furthermore, Israeli students identified with the personality traits of Conscientiousness and Emotional Stability demonstrated a negative correlation with academic dishonesty. In contrast, the personality trait of Extraversion among American students was found in a positive correlation with academic misconduct. Implications for further research are discussed.展开更多
This is a descriptive study of quantitative approach, developed at the Federal University of Rond?nia located in the Western Amazon. With the aim of analyzing the frequency of visualization of alcoholic content in the...This is a descriptive study of quantitative approach, developed at the Federal University of Rond?nia located in the Western Amazon. With the aim of analyzing the frequency of visualization of alcoholic content in the Facebook, Instagram and Snapchat, patterns of consumption, reasons that lead them to drink, most used social network and to correlate how often the users are exposed to alcoholic publications, determining if there was an important link between individual drinking practice during the beginning period and six months later. The information was obtained through the application of questionnaires for incoming students of the freshmen semester, in two moments: a period from August to December 2016/2, and, asking the same students again, from March to June 2017/1. 52.8% were males in 2016/2 and 57, 9% of females in 2017/1 with age ranging between 18 and 20 years in both periods. Facebook has proven to be the most used platform among college students. In 2016/2, 63.9% reported seeing alcohol content at Facebook and consuming that substance, comparing to Instagram with 70.4%, and to Snapchat with 74.1%. In 2017/2, academics reporting viewing alcoholic content on Facebook and consuming those alcoholic beverages accounted for 65.8%, compared to Instagram, 74.1% and Snapchat 74.4%. “Celebrating a special occasion with friends” is the most cited reason of why claim to consume alcohol. Therelation between exposure to the alcohol content of the virtual media and the network of friends was found imperceptible to the majority of the students, as they mostly do not consider themselves exposed. Many university students start the graduation already consuming alcoholic substances, which explains why there is no significant change in alcohol consumption between the observed moments, although it was found a relationship between the visualization of alcohol content in social networks and consumption, with greater impact on Snapchat.展开更多
Background: Intracranial suppurations (ICS) due to banal germs are medical-surgical emergencies, despite their little removed frequency. Represented by abscesses and empyemas, their management has been improved by the...Background: Intracranial suppurations (ICS) due to banal germs are medical-surgical emergencies, despite their little removed frequency. Represented by abscesses and empyemas, their management has been improved by the combined contributions of new diagnostic and therapeutic methods. Objective: Appreciate the management of intracranial suppurations banal germ in our service. Material and methods: A retrospective study of 41 cases of intra-cranial suppurations was conducted at Brazzaville University Hospital, from January 2007 to June 2019. Diagnostic, therapeutic and evolution aspects have been studied. Results: They are divided into 24 empyemas, 8 abscesses and 9 associations abscess-empyema. The average age was 20.2 years old in general. The male predominance is noted in all groups. The sex ratio is 3.1 for all of these intracranial suppurations (ICS). They frequently complicated Oto-Rhino-Laryngology (ORL) infections (41.4%). The clinic was mostly represented by the Bergman’s triad 51.2%, followed by headache 14.6% and seizures 12.2%. The lesions were predominant in supratentorial 97.5%. Frontal location was found in 67.4%. Germs were isolated in 29.4% of samples. There were 5 Streptococci, 3 Staphylococci and 2 Gram-negative Bacilli. The medico-surgical treatment indicated in 80.5% combined often probabilistic tri-antibiotherapy with the evacuation of the pus by the trepano-puncture. Evolution under this treatment was marked by healing in 90.2%. The lethality was 9.7%. Conclusion: The pursuit of the improvement of these infections requires the adequate treatment of their gateways, most of them loco-regional.展开更多
“The 6 ^(th) International Academic Conference of Sleep Medicine-Reelection of the Third Board of Directors of the Sleep Medicine Specialty Committee, World Federation of Chinese Medicine Societies (WFCMS)” will be ...“The 6 ^(th) International Academic Conference of Sleep Medicine-Reelection of the Third Board of Directors of the Sleep Medicine Specialty Committee, World Federation of Chinese Medicine Societies (WFCMS)” will be held from August 9th to August 11th, 2019(from Friday to Sunday). Sleep medicine is the same as many other subjects with the character that the chances are coexist with challenges and the hopes are accompanied with difficulties. In recent years, the sleep research has rapidly developed on the bases of progress of modern biological research techniques, sensing and computer technology. Sleep medicine is closely related to many different disciplines including neurology, cardiology, respiratory medicine, otolaryngology, psychological science, pediatrics, gynecology, rehabilitation, ache department and so on. In order to deepen traditional and modern multi-disciplinary research on sleep medicine, promote rapid and active development of sleep medicine, discuss advanced and perfect operating mode of discipline and department construction of sleep medicine, communicate innovative and actual fruit of sleep medicine research and construction, evoke the social attention to sleep disorders and sleep health, the 3rd International Congress on Sleep Medicine will be held.展开更多
General Secretary XI Jinping emphasized in the 60th anniversary of the establishment of the China Academy of Chinese Medical Sciences,that“Traditional Chinese medicine(TCM)is a treasure of ancient Chinese science and...General Secretary XI Jinping emphasized in the 60th anniversary of the establishment of the China Academy of Chinese Medical Sciences,that“Traditional Chinese medicine(TCM)is a treasure of ancient Chinese science and the key to the treasure house of Chinese civilization.At present,it is a golden opportunity with right timing.展开更多
Bowel obstruction is a frequent reason for hospital admissions and can be categorized into small or large,partial or complete obstructions.While small bowel obstructions occur more often,large bowel obstructions accou...Bowel obstruction is a frequent reason for hospital admissions and can be categorized into small or large,partial or complete obstructions.While small bowel obstructions occur more often,large bowel obstructions account for 20%-25%of all cases,primarily aff ecting elderly patients.[1]Malignancy is the leading cause of large bowel obstruction and is responsible for 50%-60%of cases.Other causes include idiopathic,volvulus,infl ammatory,hernia,adhesion,intussusception,endometriosis,and functional colon disorders.[1]Colonic volvulus is the third most common cause of large bowel obstruction.Most cases of colonic volvulus occur in the sigmoid(60%-70%)and cecum(25%-40%)regions.[2]In contrast,transverse colon volvulus(TCV)is rare,accounting for less than 3%of large bowel obstructions.[3]This condition has a high mortality rate of 18%-33%,predominantly due to delayed diagnosis and the absence of characteristic radiological findings.[3-5]This case report presents a rare instance of TCV obstruction in a 19-year-old patient from Mankweng Academic Hospital.展开更多
Soil improvement is one of the most important issues in geotechnical engineering practice.The wide application of traditional improvement techniques(cement/chemical materials)are limited due to damage ecological en-vi...Soil improvement is one of the most important issues in geotechnical engineering practice.The wide application of traditional improvement techniques(cement/chemical materials)are limited due to damage ecological en-vironment and intensify carbon emissions.However,the use of microbially induced calcium carbonate pre-cipitation(MICP)to obtain bio-cement is a novel technique with the potential to induce soil stability,providing a low-carbon,environment-friendly,and sustainable integrated solution for some geotechnical engineering pro-blems in the environment.This paper presents a comprehensive review of the latest progress in soil improvement based on the MICP strategy.It systematically summarizes and overviews the mineralization mechanism,influ-encing factors,improved methods,engineering characteristics,and current field application status of the MICP.Additionally,it also explores the limitations and correspondingly proposes prospective applications via the MICP approach for soil improvement.This review indicates that the utilization of different environmental calcium-based wastes in MICP and combination of materials and MICP are conducive to meeting engineering and market demand.Furthermore,we recommend and encourage global collaborative study and practice with a view to commercializing MICP technique in the future.The current review purports to provide insights for engineers and interdisciplinary researchers,and guidance for future engineering applications.展开更多
Type 2 diabetes mellitus and Parkinson's disease are chronic diseases linked to a growing pandemic that affects older adults and causes significant socio-economic burden.Epidemiological data supporting a close rel...Type 2 diabetes mellitus and Parkinson's disease are chronic diseases linked to a growing pandemic that affects older adults and causes significant socio-economic burden.Epidemiological data supporting a close relationship between these two aging-related diseases have resulted in the investigation of shared pathophysiological molecular mechanisms.Impaired insulin signaling in the brain has gained increasing attention during the last decade and has been suggested to contribute to the development of Parkinson's disease through the dysregulation of several pathological processes.The contribution of type 2 diabetes mellitus and insulin resistance in neurodegeneration in Parkinson's disease,with emphasis on brain insulin resistance,is extensively discussed in this article and new therapeutic strategies targeting this pathological link are presented and reviewed.展开更多
Introduction:Fluid and positron emission tomography(PET)biomarkers that enable the detection of the hallmark proteins of Alzheimer’s disease(AD)(amyloid and tau)have revolutionized our approach to the diagnosis of AD...Introduction:Fluid and positron emission tomography(PET)biomarkers that enable the detection of the hallmark proteins of Alzheimer’s disease(AD)(amyloid and tau)have revolutionized our approach to the diagnosis of AD.The evolution of AD diagnostic criteria to include biological characterization(Alzheimer’s Association Working Group,2023)provides an appropriate framework to reduce levels of clinico-pathologic mismatch and improve in-vivo diagnostic accuracy.As the therapeutic landscape for neurodegenerative disease evolves,it is increasingly incumbent on clinicians to provide timely,and pathologically precise diagnoses for patients.However,the expensive and invasive nature of these tests limits their scalability.展开更多
Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes mellitus.Diabetic corneal neuropathy refers to the progressive damage of corneal nerves.Diabetic retin...Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes mellitus.Diabetic corneal neuropathy refers to the progressive damage of corneal nerves.Diabetic retinopathy has traditionally been considered as damage to the retinal microvasculature.However,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural tissues.Diabetic retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular screening.However,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface impairment.Several studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic hyperglycemia.This review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal neuropathy.We also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.展开更多
The emergence of new data has always been a major force driving the advance of informetrics. The magnitude of data usage for academic literature, given by the Web of Science(Wo S), can be expected to provide a supplem...The emergence of new data has always been a major force driving the advance of informetrics. The magnitude of data usage for academic literature, given by the Web of Science(Wo S), can be expected to provide a supplementary perspective for citation analysis in three theoretical aspects, which are influence dimension, discipline difference and behavioral motive. Based on 166,767 articles in physics, computer science, economics, and Library and Information Science included by SCI and SSCI in 2013 as research samples, this paper conducts an exploratory investigation into the measurement features of the usage data. According to the results, compared with citation data, usage is more discriminative and sensitive. In terms of distribution, usage presents an approximate and positively skewed distribution at high-frequency. An approximate power-law distribution is observed in the cumulative integral. The evaluation result of usage is independent to a certain degree and poses no essential opposition to the result of citation. Although the usage of the Wo S platform still has the limitations of generality, falsifiability and isolation, usage may be accepted as one of the possible options that supplement citation data and provide a richer field of vision for influence evaluation. There are 4 figures, 6 tables and 23 references in this paper.展开更多
Type 2 diabetes mellitus(T2DM)significantly elevates the risk of colorectal cancer(CRC)and complicates its treatment by promoting chemoresistance.Poor glycemic control has been linked to exacerbated CRC progression an...Type 2 diabetes mellitus(T2DM)significantly elevates the risk of colorectal cancer(CRC)and complicates its treatment by promoting chemoresistance.Poor glycemic control has been linked to exacerbated CRC progression and diminished chemotherapy efficacy,impacting patient outcomes through various mechanisms such as oxidative stress,activation of metabolic pathways,and altered protein modifications that hinder apoptosis and enhance tumor survival.Clinical evidence shows that T2DM patients experience higher rates of chemoresistance and reduced disease-free survival and overall survival compared to non-diabetic patients.Specifically,those with poor glycemic control exhibit increased chemo-resistance and poorer survival metrics.Antidiabetic treatments,including metformin,acarbose,and gliclazide,show promise in improving chemotherapy response and glycemic management,potentially enhancing patient outcomes.Addressing this challenge requires a comprehensive,multidisciplinary approach involving oncologists,endocrino-logists,and surgeons to optimize patient care.Integrated strategies that prioritize glycemic control are essential for reducing chemoresistance and improving survival in CRC patients with T2DM.展开更多
We give a new result on the construction of K-frame generators for unitary systems by using the pseudo-inverses of involved operators,which provides an improvement to one known result on this topic.We also introduce t...We give a new result on the construction of K-frame generators for unitary systems by using the pseudo-inverses of involved operators,which provides an improvement to one known result on this topic.We also introduce the concept of K-woven generators for unitary systems,by means of which we investigate the weaving properties of K-frame generators for unitary systems.展开更多
BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social lives.However,these survivors encounter significant challenges during their...BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social lives.However,these survivors encounter significant challenges during their RTW process.Hence,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC survivors.AIM To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW outcomes.METHODS A cross-sectional investigation was adopted in this study.From September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in Chongqing.The investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and FT.To analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were used.RESULTS A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 days.Cox regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further improvement.Elevated levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC survivors.Health professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.展开更多
The article explores the pivotal moments,significant encounters,and lasting influences in the life of Austrian modernist composer Arnold Schoenberg,who spent his final 17 years in Los Angeles after fleeing Hitler’s E...The article explores the pivotal moments,significant encounters,and lasting influences in the life of Austrian modernist composer Arnold Schoenberg,who spent his final 17 years in Los Angeles after fleeing Hitler’s Europe with his family in 1933.As the United States’film capital and a city featured by the technological advancements of sound in cinema at that period,Los Angeles attracted numerous musicians,includingémigrés like Schoenberg.However,it also set limits on their professional aspirations.The article delves into Schoenberg’s legacy in the city and the efforts to preserve his memory within this cultural landscape.Through uncovering little-known,forgotten,or newly discovered facts about Schoenberg’s life,it reconstructs the vibrant cultural scene of early 20th-century Vienna and,more importantly,Los Angeles during the 1930s.The article also highlights the pedagogical aspect of Schoenberg’s activities,offering a holistic view of his multifaceted personality as a composer,artist,and teacher.展开更多
The study examines the socio-cultural context of Russian music in the decades immediately preceding and following the October Revolution of 1917,focusing on several aspects:personalities representing pre-and post-revo...The study examines the socio-cultural context of Russian music in the decades immediately preceding and following the October Revolution of 1917,focusing on several aspects:personalities representing pre-and post-revolutionary Russian(in exile)and Soviet(at home)musical activity and culture;second-tier national composers;“industrial music”of the early Soviet period;and Soviet cultural management in music behind the Iron Curtain.Portraits of composers little known to Western listeners and academic audiences are presented.The spectrum of musical styles and aesthetics is considered.Issues of ethnic diversity and religious affiliation of Russian composers are relevantly explored.Songs of the First Revolution(1905),the Civil War,and Soviet mass songs are briefly touched upon.The scope and choice of themes of the study provide a holistic approach to topics that are usually addressed separately:before or after the 1917 Revolution;classical music or folk/popular songs.展开更多
文摘Change in the information landscape has afforded librarians an opportunity to actively seek new skills,knowledge,and opportunities in order to effectively integrate expertise at the point of need; in particular,librarians have shifted from being information providers to embedded information creators,integrators,and innovators. Our ability to capitalize on the strengths of our specific institutional environments and respond to information needs is ever more important if we are to remain central to the work of our academic enterprise. This article describes how the University of North Carolina at Chapel Hill ＇ s Health Sciences Library(HSL） has sought opportunities and established successful partnerships that integrate library expertise aligning with the two core strategies of Carolina＇s new strategic framework Blueprint for Next： Of the Public,For the Public,and Innovation Made Fundamental.These efforts have resulted in initiatives that improve access to quality health care and health care information for North Carolinians,accelerate the campus＇ research enterprise,and demonstrate the importance of evidence-based care at UNC and globally. By understanding and identifying the needs of our various stakeholders,we have been able to progress with our understanding of what key problems need to be solved,what interventions need to be developed,and in what ways librarians can integrate expertise around information synthesis and critical thinking so that we are seen as valued partners in our complex academic environment.
文摘Academic dishonesty is a disturbing issue in higher education that has been worsening over the years, especially with the appearance of the internet and the e-learning education. This new technology exposes students to the opportunity of using online bank exams and term papers and increases their tendency to cheat. This study investigates student academic dishonesty in the context of traditional and distance-learning courses in higher education. Data from 1,365 students enrolled in academic institutes in the U.S.A and Israel were surveyed to assess their personality and their willingness to commit various acts of academic misconduct. The findings indicate that in both countries dishonest behaviors are greater in face-to-face courses than in online courses. In addition, both American and Israeli students identified with the personality trait of Agreeableness showed a negative correlation with academic dishonesty. Furthermore, Israeli students identified with the personality traits of Conscientiousness and Emotional Stability demonstrated a negative correlation with academic dishonesty. In contrast, the personality trait of Extraversion among American students was found in a positive correlation with academic misconduct. Implications for further research are discussed.
文摘This is a descriptive study of quantitative approach, developed at the Federal University of Rond?nia located in the Western Amazon. With the aim of analyzing the frequency of visualization of alcoholic content in the Facebook, Instagram and Snapchat, patterns of consumption, reasons that lead them to drink, most used social network and to correlate how often the users are exposed to alcoholic publications, determining if there was an important link between individual drinking practice during the beginning period and six months later. The information was obtained through the application of questionnaires for incoming students of the freshmen semester, in two moments: a period from August to December 2016/2, and, asking the same students again, from March to June 2017/1. 52.8% were males in 2016/2 and 57, 9% of females in 2017/1 with age ranging between 18 and 20 years in both periods. Facebook has proven to be the most used platform among college students. In 2016/2, 63.9% reported seeing alcohol content at Facebook and consuming that substance, comparing to Instagram with 70.4%, and to Snapchat with 74.1%. In 2017/2, academics reporting viewing alcoholic content on Facebook and consuming those alcoholic beverages accounted for 65.8%, compared to Instagram, 74.1% and Snapchat 74.4%. “Celebrating a special occasion with friends” is the most cited reason of why claim to consume alcohol. Therelation between exposure to the alcohol content of the virtual media and the network of friends was found imperceptible to the majority of the students, as they mostly do not consider themselves exposed. Many university students start the graduation already consuming alcoholic substances, which explains why there is no significant change in alcohol consumption between the observed moments, although it was found a relationship between the visualization of alcohol content in social networks and consumption, with greater impact on Snapchat.
文摘Background: Intracranial suppurations (ICS) due to banal germs are medical-surgical emergencies, despite their little removed frequency. Represented by abscesses and empyemas, their management has been improved by the combined contributions of new diagnostic and therapeutic methods. Objective: Appreciate the management of intracranial suppurations banal germ in our service. Material and methods: A retrospective study of 41 cases of intra-cranial suppurations was conducted at Brazzaville University Hospital, from January 2007 to June 2019. Diagnostic, therapeutic and evolution aspects have been studied. Results: They are divided into 24 empyemas, 8 abscesses and 9 associations abscess-empyema. The average age was 20.2 years old in general. The male predominance is noted in all groups. The sex ratio is 3.1 for all of these intracranial suppurations (ICS). They frequently complicated Oto-Rhino-Laryngology (ORL) infections (41.4%). The clinic was mostly represented by the Bergman’s triad 51.2%, followed by headache 14.6% and seizures 12.2%. The lesions were predominant in supratentorial 97.5%. Frontal location was found in 67.4%. Germs were isolated in 29.4% of samples. There were 5 Streptococci, 3 Staphylococci and 2 Gram-negative Bacilli. The medico-surgical treatment indicated in 80.5% combined often probabilistic tri-antibiotherapy with the evacuation of the pus by the trepano-puncture. Evolution under this treatment was marked by healing in 90.2%. The lethality was 9.7%. Conclusion: The pursuit of the improvement of these infections requires the adequate treatment of their gateways, most of them loco-regional.
文摘“The 6 ^(th) International Academic Conference of Sleep Medicine-Reelection of the Third Board of Directors of the Sleep Medicine Specialty Committee, World Federation of Chinese Medicine Societies (WFCMS)” will be held from August 9th to August 11th, 2019(from Friday to Sunday). Sleep medicine is the same as many other subjects with the character that the chances are coexist with challenges and the hopes are accompanied with difficulties. In recent years, the sleep research has rapidly developed on the bases of progress of modern biological research techniques, sensing and computer technology. Sleep medicine is closely related to many different disciplines including neurology, cardiology, respiratory medicine, otolaryngology, psychological science, pediatrics, gynecology, rehabilitation, ache department and so on. In order to deepen traditional and modern multi-disciplinary research on sleep medicine, promote rapid and active development of sleep medicine, discuss advanced and perfect operating mode of discipline and department construction of sleep medicine, communicate innovative and actual fruit of sleep medicine research and construction, evoke the social attention to sleep disorders and sleep health, the 3rd International Congress on Sleep Medicine will be held.
文摘General Secretary XI Jinping emphasized in the 60th anniversary of the establishment of the China Academy of Chinese Medical Sciences,that“Traditional Chinese medicine(TCM)is a treasure of ancient Chinese science and the key to the treasure house of Chinese civilization.At present,it is a golden opportunity with right timing.
文摘Bowel obstruction is a frequent reason for hospital admissions and can be categorized into small or large,partial or complete obstructions.While small bowel obstructions occur more often,large bowel obstructions account for 20%-25%of all cases,primarily aff ecting elderly patients.[1]Malignancy is the leading cause of large bowel obstruction and is responsible for 50%-60%of cases.Other causes include idiopathic,volvulus,infl ammatory,hernia,adhesion,intussusception,endometriosis,and functional colon disorders.[1]Colonic volvulus is the third most common cause of large bowel obstruction.Most cases of colonic volvulus occur in the sigmoid(60%-70%)and cecum(25%-40%)regions.[2]In contrast,transverse colon volvulus(TCV)is rare,accounting for less than 3%of large bowel obstructions.[3]This condition has a high mortality rate of 18%-33%,predominantly due to delayed diagnosis and the absence of characteristic radiological findings.[3-5]This case report presents a rare instance of TCV obstruction in a 19-year-old patient from Mankweng Academic Hospital.
基金funded by the National Natural Science Foundation of China(No.41962016)the Natural Science Foundation of NingXia(Nos.2023AAC02023,2023A1218,and 2021AAC02006).
文摘Soil improvement is one of the most important issues in geotechnical engineering practice.The wide application of traditional improvement techniques(cement/chemical materials)are limited due to damage ecological en-vironment and intensify carbon emissions.However,the use of microbially induced calcium carbonate pre-cipitation(MICP)to obtain bio-cement is a novel technique with the potential to induce soil stability,providing a low-carbon,environment-friendly,and sustainable integrated solution for some geotechnical engineering pro-blems in the environment.This paper presents a comprehensive review of the latest progress in soil improvement based on the MICP strategy.It systematically summarizes and overviews the mineralization mechanism,influ-encing factors,improved methods,engineering characteristics,and current field application status of the MICP.Additionally,it also explores the limitations and correspondingly proposes prospective applications via the MICP approach for soil improvement.This review indicates that the utilization of different environmental calcium-based wastes in MICP and combination of materials and MICP are conducive to meeting engineering and market demand.Furthermore,we recommend and encourage global collaborative study and practice with a view to commercializing MICP technique in the future.The current review purports to provide insights for engineers and interdisciplinary researchers,and guidance for future engineering applications.
基金support from Region Stockholm,ALF-project(FoUI-960041)Open Access funding is provided by Karolinska Institute(both to IM)。
文摘Type 2 diabetes mellitus and Parkinson's disease are chronic diseases linked to a growing pandemic that affects older adults and causes significant socio-economic burden.Epidemiological data supporting a close relationship between these two aging-related diseases have resulted in the investigation of shared pathophysiological molecular mechanisms.Impaired insulin signaling in the brain has gained increasing attention during the last decade and has been suggested to contribute to the development of Parkinson's disease through the dysregulation of several pathological processes.The contribution of type 2 diabetes mellitus and insulin resistance in neurodegeneration in Parkinson's disease,with emphasis on brain insulin resistance,is extensively discussed in this article and new therapeutic strategies targeting this pathological link are presented and reviewed.
文摘Introduction:Fluid and positron emission tomography(PET)biomarkers that enable the detection of the hallmark proteins of Alzheimer’s disease(AD)(amyloid and tau)have revolutionized our approach to the diagnosis of AD.The evolution of AD diagnostic criteria to include biological characterization(Alzheimer’s Association Working Group,2023)provides an appropriate framework to reduce levels of clinico-pathologic mismatch and improve in-vivo diagnostic accuracy.As the therapeutic landscape for neurodegenerative disease evolves,it is increasingly incumbent on clinicians to provide timely,and pathologically precise diagnoses for patients.However,the expensive and invasive nature of these tests limits their scalability.
文摘Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes mellitus.Diabetic corneal neuropathy refers to the progressive damage of corneal nerves.Diabetic retinopathy has traditionally been considered as damage to the retinal microvasculature.However,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural tissues.Diabetic retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular screening.However,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface impairment.Several studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic hyperglycemia.This review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal neuropathy.We also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.
基金the youth project“The Mechanism and Empirical Study of h-Type Information Network Measures”(No.71503083) supported by National Natural Science Foundation of China
文摘The emergence of new data has always been a major force driving the advance of informetrics. The magnitude of data usage for academic literature, given by the Web of Science(Wo S), can be expected to provide a supplementary perspective for citation analysis in three theoretical aspects, which are influence dimension, discipline difference and behavioral motive. Based on 166,767 articles in physics, computer science, economics, and Library and Information Science included by SCI and SSCI in 2013 as research samples, this paper conducts an exploratory investigation into the measurement features of the usage data. According to the results, compared with citation data, usage is more discriminative and sensitive. In terms of distribution, usage presents an approximate and positively skewed distribution at high-frequency. An approximate power-law distribution is observed in the cumulative integral. The evaluation result of usage is independent to a certain degree and poses no essential opposition to the result of citation. Although the usage of the Wo S platform still has the limitations of generality, falsifiability and isolation, usage may be accepted as one of the possible options that supplement citation data and provide a richer field of vision for influence evaluation. There are 4 figures, 6 tables and 23 references in this paper.
文摘Type 2 diabetes mellitus(T2DM)significantly elevates the risk of colorectal cancer(CRC)and complicates its treatment by promoting chemoresistance.Poor glycemic control has been linked to exacerbated CRC progression and diminished chemotherapy efficacy,impacting patient outcomes through various mechanisms such as oxidative stress,activation of metabolic pathways,and altered protein modifications that hinder apoptosis and enhance tumor survival.Clinical evidence shows that T2DM patients experience higher rates of chemoresistance and reduced disease-free survival and overall survival compared to non-diabetic patients.Specifically,those with poor glycemic control exhibit increased chemo-resistance and poorer survival metrics.Antidiabetic treatments,including metformin,acarbose,and gliclazide,show promise in improving chemotherapy response and glycemic management,potentially enhancing patient outcomes.Addressing this challenge requires a comprehensive,multidisciplinary approach involving oncologists,endocrino-logists,and surgeons to optimize patient care.Integrated strategies that prioritize glycemic control are essential for reducing chemoresistance and improving survival in CRC patients with T2DM.
基金Supported by NSFC(Nos.12361028,11761057)Science Foundation of Jiangxi Education Department(Nos.GJJ202302,GJJ202303,GJJ202319).
文摘We give a new result on the construction of K-frame generators for unitary systems by using the pseudo-inverses of involved operators,which provides an improvement to one known result on this topic.We also introduce the concept of K-woven generators for unitary systems,by means of which we investigate the weaving properties of K-frame generators for unitary systems.
基金Supported by the Chongqing Medical University Program for Youth Innovation in Future Medicine,No.W0019Chongqing Municipal Education Commission’s 14th Five-Year Key Discipline Support Project,No.20240101 and No.20240102。
文摘BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social lives.However,these survivors encounter significant challenges during their RTW process.Hence,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC survivors.AIM To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW outcomes.METHODS A cross-sectional investigation was adopted in this study.From September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in Chongqing.The investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and FT.To analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were used.RESULTS A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 days.Cox regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further improvement.Elevated levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC survivors.Health professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.
文摘The article explores the pivotal moments,significant encounters,and lasting influences in the life of Austrian modernist composer Arnold Schoenberg,who spent his final 17 years in Los Angeles after fleeing Hitler’s Europe with his family in 1933.As the United States’film capital and a city featured by the technological advancements of sound in cinema at that period,Los Angeles attracted numerous musicians,includingémigrés like Schoenberg.However,it also set limits on their professional aspirations.The article delves into Schoenberg’s legacy in the city and the efforts to preserve his memory within this cultural landscape.Through uncovering little-known,forgotten,or newly discovered facts about Schoenberg’s life,it reconstructs the vibrant cultural scene of early 20th-century Vienna and,more importantly,Los Angeles during the 1930s.The article also highlights the pedagogical aspect of Schoenberg’s activities,offering a holistic view of his multifaceted personality as a composer,artist,and teacher.
文摘The study examines the socio-cultural context of Russian music in the decades immediately preceding and following the October Revolution of 1917,focusing on several aspects:personalities representing pre-and post-revolutionary Russian(in exile)and Soviet(at home)musical activity and culture;second-tier national composers;“industrial music”of the early Soviet period;and Soviet cultural management in music behind the Iron Curtain.Portraits of composers little known to Western listeners and academic audiences are presented.The spectrum of musical styles and aesthetics is considered.Issues of ethnic diversity and religious affiliation of Russian composers are relevantly explored.Songs of the First Revolution(1905),the Civil War,and Soviet mass songs are briefly touched upon.The scope and choice of themes of the study provide a holistic approach to topics that are usually addressed separately:before or after the 1917 Revolution;classical music or folk/popular songs.
