Unsymmetric sulfides and selenides have great applications in the pharmaceutical field.Herein,we describe the reductive coupling reaction of xanthate esters with sulfur-containing and selenium-containing compounds(thi...Unsymmetric sulfides and selenides have great applications in the pharmaceutical field.Herein,we describe the reductive coupling reaction of xanthate esters with sulfur-containing and selenium-containing compounds(thio(seleno)sulfonates and disulfides(selenides))under the nickel-catalyzed condition.It provides a mild and effective method for the synthesis of unsymmetric sulfides and selenides which has the advantages of mild reaction conditions,high yields and a wide range of substrates.展开更多
基金National Natural Science Foundation of China(Nos.21971174 and U2267224),PAPD,Cyrus Tang(Zhongying)Scholar,Jiangsu Qing-Lan Project for Young and Middle-aged Academic Leaders(2023)and Soochow University for financialsupport.
文摘Unsymmetric sulfides and selenides have great applications in the pharmaceutical field.Herein,we describe the reductive coupling reaction of xanthate esters with sulfur-containing and selenium-containing compounds(thio(seleno)sulfonates and disulfides(selenides))under the nickel-catalyzed condition.It provides a mild and effective method for the synthesis of unsymmetric sulfides and selenides which has the advantages of mild reaction conditions,high yields and a wide range of substrates.
