In the past few decades,the navigation performance of ships and structures in ice-covered waters has not been fully studied,especially the influence of ice mechanical properties on icebreaking ability.Ice bending stre...In the past few decades,the navigation performance of ships and structures in ice-covered waters has not been fully studied,especially the influence of ice mechanical properties on icebreaking ability.Ice bending strength is a key ice parameter for predicting ship ice loads,and accurate ice bending strength is also the key to scaling model tests results to real ship.However,numerical simulation studies on model ice bending strength of ice tanks are often neglected.In this paper,an explicit finite element method model is used to simulate the ice cantilever beam test,and the failure load and bending strength of the ice are obtained.In this model,the Tsai-Wu failure criterion is used as the material constitutive model,and the required simulation parameters are obtained from the model ice test in ice tank.Parameter sensitivity analysis shows that the cantilever beam size of the model ice has a significant effect on the flexural strength.The results show that proper rounding at the root of the cantilever beam is beneficial to reduce stress concentration and obtain more accurate bending strength;the thickness,width and length of the cantilever beam should conform to a certain ratio,and consistent with the ITTC recommended reference.Therefore,the results of this study can promote model ice experiments and numerical studies and provide ice strength data support for ship design and polar ship maneuvering.展开更多
The Chinese Opera Season 2025 and International Exhibition of Chinese Opera opened in Vienna,the capital of Austria,on the evening of April 5.As the opening performance of the Season,a traditional Wu Opera(a local ope...The Chinese Opera Season 2025 and International Exhibition of Chinese Opera opened in Vienna,the capital of Austria,on the evening of April 5.As the opening performance of the Season,a traditional Wu Opera(a local opera in Zhejiang Province)scene"the Legend of the White Snake"was performed at the Muth Theatre in Vienna,drawing enthusiastic responses.展开更多
Objective:To evaluate the efficacy of the modified Gui Fu Ling Wu Decoction in treating diabetic nephropathy(DN)of the spleen-kidney Yang deficiency type.Methods:A total of 100 DN patients admitted to Changyi Traditio...Objective:To evaluate the efficacy of the modified Gui Fu Ling Wu Decoction in treating diabetic nephropathy(DN)of the spleen-kidney Yang deficiency type.Methods:A total of 100 DN patients admitted to Changyi Traditional Chinese Medicine Hospital between August 2023 and March 2024 were included in the study.Patients were randomly divided into a control group and a study group,each comprising 50 cases,using a computerized random number generator.The control group received kallikrein treatment,while the study group received a combination of kallikrein and the modified Gui Fu Ling Wu Decoction.Blood glucose control,renal function,and inflammatory markers were assessed before and after treatment in both groups.Results:Before treatment,there were no significant differences in blood glucose and renal function indicators between the two groups(P>0.05).After treatment,postprandial blood glucose,fasting blood glucose,24-hour urinary protein,urinary microalbumin,serum creatinine,serum C-reactive protein(CRP),and interleukin-6 levels significantly decreased in both groups,with the study group showing superior results compared to the control group(P<0.05).Conclusion:The combination of Gui Fu Ling Wu Decoction and kallikrein for treating spleen-kidney Yang deficiency type DN significantly improves blood glucose control,enhances renal function,and reduces inflammatory responses.展开更多
From the perspective of Xiang thinking(象思维imagery thinking),the application of Wu Xing(五行five elements)in traditional Chinese medicine(TCM)provides a reasonable cognitive model.Wu Xing with the earth in the cent...From the perspective of Xiang thinking(象思维imagery thinking),the application of Wu Xing(五行five elements)in traditional Chinese medicine(TCM)provides a reasonable cognitive model.Wu Xing with the earth in the center(中土五行)helps TCM establish extensive connections between the human body and the universe,while Wu Xing in the generating and conquering cycles(生克五行)incorporates everything into a systematic thinking framework through complex dialectical relationships,becoming an ideal cognitive tool for TCM diagnosis and treatment.In essence,Wu Xing represents an upgrade of yin-yang dialectical thinking into a two-dimensional Xiang thinking diagram,possessing powerful explanatory capabilities.When faced with complex life systems,Wu Xing provides TCM with a theoretical framework,and TCM,in turn,offers a practical application for Wu Xing.展开更多
This paper conducts an in-depth analysis of the theory and methods for differentiating and treating insomnia in Bu Ju Ji by Wu Cheng,a physician of the Qing Dynasty.By systematically sorting out the origin of Wu Cheng...This paper conducts an in-depth analysis of the theory and methods for differentiating and treating insomnia in Bu Ju Ji by Wu Cheng,a physician of the Qing Dynasty.By systematically sorting out the origin of Wu Cheng’s academic thoughts,this study explores his unique perspective on differentiating and treating insomnia,analyzes the compatibility rules of his core formulas and herbs,and reveals the characteristics of his medication use as well as its guiding value for later clinical practice.Research shows that Wu Cheng integrated the principles of the I Ching(Book of Changes)with medical theories to construct a theoretical system for consumptive diseases.In the differentiation and treatment of insomnia,he emphasized the dynamic balance of zang-fu organs,Qi,blood,Yin and Yang,with special attention to the impact of spleen-Yin deficiency on insomnia.He thus formed distinctive academic features,including treating both deficiency and excess,taking into account both Qi and blood,and regulating the spleen to protect the body’s defense system.In terms of medication,he was skilled in using herbs that are sweet and warm in nature for tonification,harmonizing Qi and blood,and invigorating the spleen to nourish Yin.These insights hold significant reference value for modern TCM(Traditional Chinese Medicine)in the treatment of insomnia.展开更多
In the context of Western medicine,Xin(心heart),Gan(肝liver),Pi(脾spleen),Fei(肺lung),and Shen(肾kidney)are five specific organs,while in ancient Chinese medicine,they are five kinds of Zang Xiang(藏象visceral manifes...In the context of Western medicine,Xin(心heart),Gan(肝liver),Pi(脾spleen),Fei(肺lung),and Shen(肾kidney)are five specific organs,while in ancient Chinese medicine,they are five kinds of Zang Xiang(藏象visceral manifestation),often referred to as Wu Zang(五藏five zang-organs),representing five interrelated structural-functional systems.There are both differences and connections between visceral manifestations and organs,which are reflected in the theories of Wu Zang.The specific connotation of Wu Zang are determined by the specific context in which they are located.With the accumulation of practice,the Wu Zang of the human body structures and functions,as well as the relationship between the Wu Zang have been in constant development and change.The encounter of Chinese and Western medicine in the 19th century dramatically changed the connotation of Wu Zang,from emphasizing visceral manifestations and neglecting substance to an organs-oriented perspective.This article examines how the encounter of Chinese and Western medicine in China influenced Chinese medicine.By analyzing three key aspects:(1)the interpretation of Wu Zang in pre-16th century texts;(2)the evolution and dissemination of Western medicine during the Ming and Qing dynasties;(3)the shifting conceptualization of Wu Zang in late Qing medical literature—the study elucidates the transformative impact of this cross-cultural medical encounter on the theory and practice of Chinese medicine.展开更多
BACKGROUND Lung cancer(LC)combined with chronic obstructive pulmonary disease(COPD)is a common combination of comorbidities.Anti-inflammation and modulation of oxidative/antioxidative imbalance may prevent COPD-induce...BACKGROUND Lung cancer(LC)combined with chronic obstructive pulmonary disease(COPD)is a common combination of comorbidities.Anti-inflammation and modulation of oxidative/antioxidative imbalance may prevent COPD-induced LC,and are also crucial to the treatment of LC combined with COPD.Modern studies have shown that Tao Hong Si Wu Tang(THSW)has vasodilatory,anti-inflammatory,anti-fatigue,anti-shock,immunoregulatory,lipid-reducing,micronutrient-supplementing,and anti-allergy effects.AIM To observe the effects of THSW on COPD and LC in mice.METHODS A total of 100 specific pathogen-free C57/BL6 mice were randomly divided into five groups:Blank control group(group A),model control group(group B),THSW group(group C),IL-6 group(group D),and THSW+IL-6 group(group E),with 20 mice in each group.A COPD mouse model was established using fumigation plus lipopolysaccharide intra-airway drip,and an LC model was replicated by in situ inoculation using the Lewis cell method.RESULTS The blank control group exhibited a clear alveolar structure.The model control and IL-6 groups had thickened alveolar walls,with smaller alveolar lumens,interstitial edema,and several inflammatory infiltrating cells.Histopathological changes in the lungs of the THSW and THSW+IL-6 groups were less than those of the model control group.The serum IL-1β,IL-6,and TNF-αlevels and IL-6R,JAK,p-JAK,STAT1/3,p-STAT1/3,FOXO,p-FOXO,and IL-7R expression levels in lung tissues of mice in the rest of the groups were significantly higher than those of the blank control group(P<0.01).Compared with the model control group,the IL-6 group demonstrated significantly higher levels for the abovementioned proteins in the serum and lung tissues(P<0.01),and the THSW group had significantly higher serum IL-1β,IL-6,and TNF-αlevels and IL-7R expression levels in lung tissues(P<0.01)but significantly decreased IL-6R,JAK,p-JAK,STAT1/3,p-STAT1/3,FOXO,p-FOXO,and IL-7R levels(P<0.01).CONCLUSION THSW reduces the serum IL-1β,IL-6,and TNF-αlevels in the mouse model with anti-inflammatory effects.Its antiinflammatory mechanism lies in inhibiting the overactivation of the JAK/STAT1/3 signaling pathway.展开更多
Dachuan Baijie Muddymen Dance is a kind of dance with local characteristics.From its dance movements and prop usage,it should be related to ancient Ba people’s war dance,as well as to recorded ancient dances such as...Dachuan Baijie Muddymen Dance is a kind of dance with local characteristics.From its dance movements and prop usage,it should be related to ancient Ba people’s war dance,as well as to recorded ancient dances such as“Da Xia”and“Da Wu”.展开更多
“[ã^(44) kã^(44) paʔ^(5) lã44 tã^(53)]”(Chinese characters transcription“昂更八冷打”)is an colloquial expression in Tongxiang dialect of Suzhou-Jiaxing-Huzhou Sub-branch,Taihu Branch,Wu.It describes an awkward...“[ã^(44) kã^(44) paʔ^(5) lã44 tã^(53)]”(Chinese characters transcription“昂更八冷打”)is an colloquial expression in Tongxiang dialect of Suzhou-Jiaxing-Huzhou Sub-branch,Taihu Branch,Wu.It describes an awkward state with unfinished tasks.Its similar expressions can be found in other regions of Taihu Branch,including Yixing,Changzhou,Shaoxing and Ningbo,usually serving as“all”,while the expression“[hÃɲ^(33) paʔ^(3) lÃɲ^(33) tÃɲ^(31)]”(“亨八冷打”)in Shanghai Sub-branch indicates“the remaining parts”when used alone.“[hÃɲ^(33) paʔ^(3) lÃɲ^(33) tÃɲ^(31)]”stands for“all”only when followed by a word with meaning of“adding together”.In this paper,it is concluded and deduced from other similar morphemes that the contradictory connotations are related to an“inner split”process of an original word.Considering similar morphemes in other Chinese dialects(including Cantonese,Hakka,Jianghuai and Min),the following analysis proposes three possible original expressions and correlating trajectories of this inner phonetic-semantic split process,and selects a most credible way based on the rhyming dictionary and previous reconstructive models of ancient Chinese phonology.This presumptive analysis indicates that a broader“split and derivate”process generating new morphemes exists widely in Sinitic dialects as a natural company of phonetic features in Chinese language flow.展开更多
WU polyomavirus,which was firstly discovered in 2007,is a new human polyomavirus belonging to Polyomaviridae and containing circular double-stranded genomic DNA.In this study,the 278 clinical sputum specimens from chi...WU polyomavirus,which was firstly discovered in 2007,is a new human polyomavirus belonging to Polyomaviridae and containing circular double-stranded genomic DNA.In this study,the 278 clinical sputum specimens from children under 5 years old were collected from Wenzhou Medical College affiliated Wenling First Hospital,Zhejiang Province.Based on identification assay of WU polyomavirus previously reported,a WU polyomavirus was identified from clinical samples successfully,the positive rate was 0.4%.The sequences of PCR products were identical to that of VP2 gene and large T antigen gene derived from WU polyomavirus reported.The above results strongly suggested that the WU polyomavirus isolated was firstly found in Chinese children with acute lower respiratory tract infections.This study provides a firm basis for further research of WU polyomavirus.展开更多
文摘In the past few decades,the navigation performance of ships and structures in ice-covered waters has not been fully studied,especially the influence of ice mechanical properties on icebreaking ability.Ice bending strength is a key ice parameter for predicting ship ice loads,and accurate ice bending strength is also the key to scaling model tests results to real ship.However,numerical simulation studies on model ice bending strength of ice tanks are often neglected.In this paper,an explicit finite element method model is used to simulate the ice cantilever beam test,and the failure load and bending strength of the ice are obtained.In this model,the Tsai-Wu failure criterion is used as the material constitutive model,and the required simulation parameters are obtained from the model ice test in ice tank.Parameter sensitivity analysis shows that the cantilever beam size of the model ice has a significant effect on the flexural strength.The results show that proper rounding at the root of the cantilever beam is beneficial to reduce stress concentration and obtain more accurate bending strength;the thickness,width and length of the cantilever beam should conform to a certain ratio,and consistent with the ITTC recommended reference.Therefore,the results of this study can promote model ice experiments and numerical studies and provide ice strength data support for ship design and polar ship maneuvering.
文摘The Chinese Opera Season 2025 and International Exhibition of Chinese Opera opened in Vienna,the capital of Austria,on the evening of April 5.As the opening performance of the Season,a traditional Wu Opera(a local opera in Zhejiang Province)scene"the Legend of the White Snake"was performed at the Muth Theatre in Vienna,drawing enthusiastic responses.
基金Shandong Province Traditional Chinese Medicine Science and Technology Project(Project No.M-2023290)。
文摘Objective:To evaluate the efficacy of the modified Gui Fu Ling Wu Decoction in treating diabetic nephropathy(DN)of the spleen-kidney Yang deficiency type.Methods:A total of 100 DN patients admitted to Changyi Traditional Chinese Medicine Hospital between August 2023 and March 2024 were included in the study.Patients were randomly divided into a control group and a study group,each comprising 50 cases,using a computerized random number generator.The control group received kallikrein treatment,while the study group received a combination of kallikrein and the modified Gui Fu Ling Wu Decoction.Blood glucose control,renal function,and inflammatory markers were assessed before and after treatment in both groups.Results:Before treatment,there were no significant differences in blood glucose and renal function indicators between the two groups(P>0.05).After treatment,postprandial blood glucose,fasting blood glucose,24-hour urinary protein,urinary microalbumin,serum creatinine,serum C-reactive protein(CRP),and interleukin-6 levels significantly decreased in both groups,with the study group showing superior results compared to the control group(P<0.05).Conclusion:The combination of Gui Fu Ling Wu Decoction and kallikrein for treating spleen-kidney Yang deficiency type DN significantly improves blood glucose control,enhances renal function,and reduces inflammatory responses.
文摘From the perspective of Xiang thinking(象思维imagery thinking),the application of Wu Xing(五行five elements)in traditional Chinese medicine(TCM)provides a reasonable cognitive model.Wu Xing with the earth in the center(中土五行)helps TCM establish extensive connections between the human body and the universe,while Wu Xing in the generating and conquering cycles(生克五行)incorporates everything into a systematic thinking framework through complex dialectical relationships,becoming an ideal cognitive tool for TCM diagnosis and treatment.In essence,Wu Xing represents an upgrade of yin-yang dialectical thinking into a two-dimensional Xiang thinking diagram,possessing powerful explanatory capabilities.When faced with complex life systems,Wu Xing provides TCM with a theoretical framework,and TCM,in turn,offers a practical application for Wu Xing.
基金Key Scientific Research Project of Anhui Provincial Department of Education in 2021,“Literature Collation of Insomnia Syndrome in Xin’an Medical Classics and Analysis of Its Related Academic Thoughts”(Project No.:KJ2021A1282)Wanjiang Pilot Zone Project in 2021,“Modern Apprenticeship System for TCM(Traditional Chinese Medicine)Mentorship Education”(Project No.:WJ-RCPY-037)2023 Anhui Provincial-Level High-Level Vocational Colleges and High-Level Professional Groups,TCM Professional Group(Project No.:Wan Jiao Mi Gao[2023]No.5)。
文摘This paper conducts an in-depth analysis of the theory and methods for differentiating and treating insomnia in Bu Ju Ji by Wu Cheng,a physician of the Qing Dynasty.By systematically sorting out the origin of Wu Cheng’s academic thoughts,this study explores his unique perspective on differentiating and treating insomnia,analyzes the compatibility rules of his core formulas and herbs,and reveals the characteristics of his medication use as well as its guiding value for later clinical practice.Research shows that Wu Cheng integrated the principles of the I Ching(Book of Changes)with medical theories to construct a theoretical system for consumptive diseases.In the differentiation and treatment of insomnia,he emphasized the dynamic balance of zang-fu organs,Qi,blood,Yin and Yang,with special attention to the impact of spleen-Yin deficiency on insomnia.He thus formed distinctive academic features,including treating both deficiency and excess,taking into account both Qi and blood,and regulating the spleen to protect the body’s defense system.In terms of medication,he was skilled in using herbs that are sweet and warm in nature for tonification,harmonizing Qi and blood,and invigorating the spleen to nourish Yin.These insights hold significant reference value for modern TCM(Traditional Chinese Medicine)in the treatment of insomnia.
基金financed by the grant from The MUST Faculty Research Grants(FRG-25-031-FC)and Fundação Macao.
文摘In the context of Western medicine,Xin(心heart),Gan(肝liver),Pi(脾spleen),Fei(肺lung),and Shen(肾kidney)are five specific organs,while in ancient Chinese medicine,they are five kinds of Zang Xiang(藏象visceral manifestation),often referred to as Wu Zang(五藏five zang-organs),representing five interrelated structural-functional systems.There are both differences and connections between visceral manifestations and organs,which are reflected in the theories of Wu Zang.The specific connotation of Wu Zang are determined by the specific context in which they are located.With the accumulation of practice,the Wu Zang of the human body structures and functions,as well as the relationship between the Wu Zang have been in constant development and change.The encounter of Chinese and Western medicine in the 19th century dramatically changed the connotation of Wu Zang,from emphasizing visceral manifestations and neglecting substance to an organs-oriented perspective.This article examines how the encounter of Chinese and Western medicine in China influenced Chinese medicine.By analyzing three key aspects:(1)the interpretation of Wu Zang in pre-16th century texts;(2)the evolution and dissemination of Western medicine during the Ming and Qing dynasties;(3)the shifting conceptualization of Wu Zang in late Qing medical literature—the study elucidates the transformative impact of this cross-cultural medical encounter on the theory and practice of Chinese medicine.
基金Supported by Liaoning Province“Xingliao Talent Program”Project,No.XLYC2007019.
文摘BACKGROUND Lung cancer(LC)combined with chronic obstructive pulmonary disease(COPD)is a common combination of comorbidities.Anti-inflammation and modulation of oxidative/antioxidative imbalance may prevent COPD-induced LC,and are also crucial to the treatment of LC combined with COPD.Modern studies have shown that Tao Hong Si Wu Tang(THSW)has vasodilatory,anti-inflammatory,anti-fatigue,anti-shock,immunoregulatory,lipid-reducing,micronutrient-supplementing,and anti-allergy effects.AIM To observe the effects of THSW on COPD and LC in mice.METHODS A total of 100 specific pathogen-free C57/BL6 mice were randomly divided into five groups:Blank control group(group A),model control group(group B),THSW group(group C),IL-6 group(group D),and THSW+IL-6 group(group E),with 20 mice in each group.A COPD mouse model was established using fumigation plus lipopolysaccharide intra-airway drip,and an LC model was replicated by in situ inoculation using the Lewis cell method.RESULTS The blank control group exhibited a clear alveolar structure.The model control and IL-6 groups had thickened alveolar walls,with smaller alveolar lumens,interstitial edema,and several inflammatory infiltrating cells.Histopathological changes in the lungs of the THSW and THSW+IL-6 groups were less than those of the model control group.The serum IL-1β,IL-6,and TNF-αlevels and IL-6R,JAK,p-JAK,STAT1/3,p-STAT1/3,FOXO,p-FOXO,and IL-7R expression levels in lung tissues of mice in the rest of the groups were significantly higher than those of the blank control group(P<0.01).Compared with the model control group,the IL-6 group demonstrated significantly higher levels for the abovementioned proteins in the serum and lung tissues(P<0.01),and the THSW group had significantly higher serum IL-1β,IL-6,and TNF-αlevels and IL-7R expression levels in lung tissues(P<0.01)but significantly decreased IL-6R,JAK,p-JAK,STAT1/3,p-STAT1/3,FOXO,p-FOXO,and IL-7R levels(P<0.01).CONCLUSION THSW reduces the serum IL-1β,IL-6,and TNF-αlevels in the mouse model with anti-inflammatory effects.Its antiinflammatory mechanism lies in inhibiting the overactivation of the JAK/STAT1/3 signaling pathway.
基金Research Center for the Protection and Development of Tangible Cultural Heritage in East Sichuan in 2022 (Project No.2022YB17)2018 Sichuan University of Arts and Sciences Ba Culture Research Special Project“Ba Culture Literature Compilation and Research” (Project Number:2018BWH001Z).
文摘Dachuan Baijie Muddymen Dance is a kind of dance with local characteristics.From its dance movements and prop usage,it should be related to ancient Ba people’s war dance,as well as to recorded ancient dances such as“Da Xia”and“Da Wu”.
文摘“[ã^(44) kã^(44) paʔ^(5) lã44 tã^(53)]”(Chinese characters transcription“昂更八冷打”)is an colloquial expression in Tongxiang dialect of Suzhou-Jiaxing-Huzhou Sub-branch,Taihu Branch,Wu.It describes an awkward state with unfinished tasks.Its similar expressions can be found in other regions of Taihu Branch,including Yixing,Changzhou,Shaoxing and Ningbo,usually serving as“all”,while the expression“[hÃɲ^(33) paʔ^(3) lÃɲ^(33) tÃɲ^(31)]”(“亨八冷打”)in Shanghai Sub-branch indicates“the remaining parts”when used alone.“[hÃɲ^(33) paʔ^(3) lÃɲ^(33) tÃɲ^(31)]”stands for“all”only when followed by a word with meaning of“adding together”.In this paper,it is concluded and deduced from other similar morphemes that the contradictory connotations are related to an“inner split”process of an original word.Considering similar morphemes in other Chinese dialects(including Cantonese,Hakka,Jianghuai and Min),the following analysis proposes three possible original expressions and correlating trajectories of this inner phonetic-semantic split process,and selects a most credible way based on the rhyming dictionary and previous reconstructive models of ancient Chinese phonology.This presumptive analysis indicates that a broader“split and derivate”process generating new morphemes exists widely in Sinitic dialects as a natural company of phonetic features in Chinese language flow.
文摘WU polyomavirus,which was firstly discovered in 2007,is a new human polyomavirus belonging to Polyomaviridae and containing circular double-stranded genomic DNA.In this study,the 278 clinical sputum specimens from children under 5 years old were collected from Wenzhou Medical College affiliated Wenling First Hospital,Zhejiang Province.Based on identification assay of WU polyomavirus previously reported,a WU polyomavirus was identified from clinical samples successfully,the positive rate was 0.4%.The sequences of PCR products were identical to that of VP2 gene and large T antigen gene derived from WU polyomavirus reported.The above results strongly suggested that the WU polyomavirus isolated was firstly found in Chinese children with acute lower respiratory tract infections.This study provides a firm basis for further research of WU polyomavirus.
