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面板数据模型基于Within估计的最优设计 被引量:2
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作者 程靖 岳荣先 王萍 《统计与决策》 CSSCI 北大核心 2018年第23期30-32,共3页
文章研究面板数据模型的最优设计。证明了矩形设计域[a,c]×[b,d]上该模型基于Within估计的几类最优恒等设计可以在设计域的四个顶点处获得;特别的是在对称的矩形设计域上,设计域四个顶点处的等权重设计同时具备D-、A-和I-最优性。
关键词 面板数据模型 最优设计 恒等设计 within估计
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介词in和within的认知对比分析
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作者 田薇 《湖北文理学院学报》 2015年第10期63-66,共4页
介词in和within意义上有相似之处,学习者在理解和应用过程中时常混淆。运用原型范畴理论和意向图式理论分析原型语义,提出两个介词的第一个差异:in体现出了容器图式,而within则是中心-边缘的范例;两个介词存在着隐喻意义扩展能力的不同... 介词in和within意义上有相似之处,学习者在理解和应用过程中时常混淆。运用原型范畴理论和意向图式理论分析原型语义,提出两个介词的第一个差异:in体现出了容器图式,而within则是中心-边缘的范例;两个介词存在着隐喻意义扩展能力的不同,in所拓展的目标域比within要多,隐喻引申也就更多。教师在教学中应该多从认知角度出发,解释词义的认知来源,启发学生摆脱表征现象而深究认知根源,教师和学生都将受益匪浅。 展开更多
关键词 认知语言学 介词IN 介词within 认知对比
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Panel Data模型基于Within估计的最优设计 被引量:1
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作者 程靖 岳荣先 《应用概率统计》 CSCD 北大核心 2018年第1期95-100,共6页
本文研究二元Panel Data模型基于Within估计在恒等设计类中的D-,A-,I-和E-最优设计.文章首先证明了二元Panel Data模型基于Within估计在恒等设计类中的几类最优设计可在设计域的顶点处获得;研究发现模型的D-,A-和E-最优设计均为设计域... 本文研究二元Panel Data模型基于Within估计在恒等设计类中的D-,A-,I-和E-最优设计.文章首先证明了二元Panel Data模型基于Within估计在恒等设计类中的几类最优设计可在设计域的顶点处获得;研究发现模型的D-,A-和E-最优设计均为设计域顶点上的等权重设计,I-最优设计为对称设计;结果还表明等权重设计具有较高的I-效. 展开更多
关键词 PANELDATA模型 within估计 最优设计
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Distribution and controls of petroliferous plays in subtle traps within a Paleogene lacustrine sequence stratigraphic framework, Dongying Depression, Bohai Bay Basin, Eastern China 被引量:2
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作者 Ji-Chang Zhu Cai-Neng Zou +4 位作者 You-Liang Feng Shu Jiang Wei-An Wu Ri-xiang Zhu Miao Yuan 《Petroleum Science》 SCIE CAS CSCD 2020年第1期1-22,共22页
The characteristics of petroliferous plays in subtle traps within a sequence stratigraphic framework in the Dongying Depression are investigated in this study.Sand bodies within lowstand systems tracts(LSTs)of sequenc... The characteristics of petroliferous plays in subtle traps within a sequence stratigraphic framework in the Dongying Depression are investigated in this study.Sand bodies within lowstand systems tracts(LSTs)of sequences,comprising incisedchannel fills,sublacustrine fans,deltas in LSTs,controlled by syndepositional normal faults,and sand bodies within transgressive systems tracts(TSTs)to early highstand systems tracts(HSTs),consisting of beach bars,and turbidites,controlled by the prodelta slope,paleorelief,and syndepositional normal faults,are good subtle reservoirs.Mudstones and shale of deep lake subfacies in TSTs to early HSTs of sequences are source and cap rocks.Abnormal overpressure is the dominant dynamic factor for hydrocarbon migration from source rock to the subtle traps.Normal faults,sand bodies,and unconformities function as conduit systems.Sand bodies distributed in the abnormal overpressure source rocks within LSTs to early HSTs are petroliferous plays in lithologic traps.The petroliferous plays in stratigraphic traps are controlled by unconformities at margins of the Depression. 展开更多
关键词 Subtle traps Sand bodies within lowstand systems TRACT Syndepositional normal fault Abnormal OVERPRESSURE Dongying Depression
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Changes in stress within grassland ecosystems in the three counties of the source regions of the Yangtze and Yellow Rivers 被引量:2
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作者 Fang, YiPing Qin, DaHe Ding, YongJian 《Journal of Arid Land》 SCIE 2010年第2期116-122,共7页
Based on a database of more than 40 years of second production process and energy flow records for Maduo,Qumalai and Yushu counties,a dynamic model of the stress within grassland ecosys-tems was established using a no... Based on a database of more than 40 years of second production process and energy flow records for Maduo,Qumalai and Yushu counties,a dynamic model of the stress within grassland ecosys-tems was established using a nonlinear regression method for this source regions of the Yangtze and Yel-low Rivers.The results show that dynamic curves of stress within grassland ecosystems in the three coun-ties were in the shape of an inverted 'U' during the period 1965-2007.It also revealed that the variation in actual amount of livestock inventories reflected the general trends of the stress within the grassland eco-systems in the source regions,although there were many other factors for the increase or reduction in grassland ecosystem stress. 展开更多
关键词 the source regions of Yangtze and Yellow Rivers the stress within grassland ecosystems inverted 'U' model DRIVER
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Unifying the theory of integration within normal-,Weyl- and antinormal-ordering of operators and the s-ordered operator expansion formula of density operators 被引量:2
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作者 范洪义 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第5期41-47,共7页
By introducing the s-parameterized generalized Wigner operator into phase-space quantum mechanics we invent the technique of integration within s-ordered product of operators (which considers normally ordered, antino... By introducing the s-parameterized generalized Wigner operator into phase-space quantum mechanics we invent the technique of integration within s-ordered product of operators (which considers normally ordered, antinormally ordered and Weyl ordered product of operators as its special cases). The s-ordered operator expansion (denoted by s…s ) formula of density operators is derived, which isρ=2/1-s∫d^2β/π〈-β|ρ|β〉sexp{2/s-1(s|β|^2-β*α+βa-αα)}s The s-parameterized quantization scheme is thus completely established. 展开更多
关键词 s-parameterized generalized Wigner operator technique of integration within s-ordered product of operators s-ordered operator expansion formula s-parameterized quantization scheme
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Source and Inheritance of the Within Cultivar Residual Variation Detected in an indica Variety IR64
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作者 WU Jian-li SHI Yong-feng +4 位作者 CHEN Jie Casiana Vera CRUZ ZHUANG Jie-yun Hei LEUNG ZHENG Kang-le 《Rice science》 SCIE 2007年第1期21-26,共6页
The phenotypically uniform indica variety IR64 was chosen for study of the source and inheritance of within cultivar residual variation using a set of SSR markers. Residual heterogeneity in IR64 was identified on the ... The phenotypically uniform indica variety IR64 was chosen for study of the source and inheritance of within cultivar residual variation using a set of SSR markers. Residual heterogeneity in IR64 was identified on the short arm of chromosome 2 involving at least 5 SSR loci spanning nearly 30 cM. The SSR variations originated from the parental lines of IR64 (IR5657-33-2 / IR2061-465-1-5-5) and were segregating in the selfed bulk seed stock in a Mendelian manner for more than 20 years. This study verified that the within cultivar variations of SSR in a morphologically uniform variety IR64 of a selfing crop came from its parental lines, which has immediate and commercial applications including test of hybrid seed purity, varietal fingerprinting, and curation and propagation of germplasm collections. 展开更多
关键词 simple sequence repeat residual heterogeneity within cultivar variation rice
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Genetic Variations and Cultivar Purity within the G. <i>hirsutum</i>Cultivars via RAPD Marker
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作者 Farah Raheel Muhammad Kauser Nawaz Shah +2 位作者 Muhammad Shahid Iqbal Ijaz Rasool Noorka Zareen Sarfraz 《American Journal of Plant Sciences》 2015年第2期392-404,共13页
To assess genetic variation within a cultivar, four commercial varieties with five individual G. hirsutum genotypes and their bulk were assayed with selected forty 10-mer RAPDs per cultivar via PCR. CIM-473 cultivar s... To assess genetic variation within a cultivar, four commercial varieties with five individual G. hirsutum genotypes and their bulk were assayed with selected forty 10-mer RAPDs per cultivar via PCR. CIM-473 cultivar showed amplification of 321 bands in total per primer with an average of 8 bands. A range of similarity i.e.;80% - 100% within the cultivar has been observed for minimum and maximum respectively. CIM-448 showed amplification of 300 bands in total per primer with an average of 7.5 bands. Maximum similarity of 95% and minimum similarity of 84% was observed within the cultivar. In CIM-1100 the total numbers of fragments amplified are 304, with the average of 7.6 bands per primer and are 12% - 20% polymorphic. Similarly, in NIAB-78 the total numbers of fragments amplified were 310, with the average of 7.7 bands per primer. The reliability of RAPD technique for finding genetic resemblances is indicated by the mentioned results. Numerous groups within 5 individual genotypes bulk among 4 cultivars of G. hirsutum L. have been through cluster analysis which was by the unweighted pair group method of arithmetic means (UPGMA). Dendrograms have been used for showing cultivar relationship. 展开更多
关键词 POLYMERASE Chain Reaction (PCR) G. hirsutum RAPD Variation within the CULTIVARS
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Clustering Categorical Data Based on Within-Cluster Relative Mean Difference
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作者 Jinxia Su Chunjing Su 《Open Journal of Statistics》 2017年第2期173-181,共9页
The clustering on categorical variables has received intensive attention. In dataset with categorical features, some features show the superior performance on clustering procedure. In this paper, we propose a simple m... The clustering on categorical variables has received intensive attention. In dataset with categorical features, some features show the superior performance on clustering procedure. In this paper, we propose a simple method to find such distinctive features by comparing pooled within-cluster mean relative difference and then partition the data upon such features and give subspace of the subgroups. The applications on zoo data and soybean data illustrate the performance of the proposed method. 展开更多
关键词 CLUSTERING CATEGORICAL Variable Distinctive Attribute Pooled within-Cluster Mean RELATIVE DIFFERENCE Hamming Distance
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A Within-Host Model of Dengue Infection with a Non-Constant Monocyte Production Rate
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作者 Jeremy J. Thibodeaux Michael Hennessey 《Applied Mathematics》 2016年第18期2382-2393,共12页
In this paper we modify previous models to develop a new model of within-host dengue infection without the assumption that monocyte production is constant. We show that this new model exhibits behavior not seen in pre... In this paper we modify previous models to develop a new model of within-host dengue infection without the assumption that monocyte production is constant. We show that this new model exhibits behavior not seen in previous models. We then proceed by obtaining an expression for the net reproductive rate of the virus and thus establish a stability result. We also perform a sensitivity analysis to test various treatment strategies and find that two strategies might be fruitful. One is the reduction of the infection rate of monocytes by viruses and the other, more effective, theoretical approach is to reduce the number of new viruses per infected monocyte. 展开更多
关键词 DENGUE within-Host Model Net Reproductive Rate Treatment Scenarios
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Empirical Likelihood Analysis of Longitudinal Data Involving Within-subject Correlation 被引量:2
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作者 Shuang HU Lu LIN 《Acta Mathematicae Applicatae Sinica》 SCIE CSCD 2012年第4期731-744,共14页
In this paper we use profile empirical likelihood to construct confidence regions for regression coefficients in partially linear model with longitudinal data. The main contribution is that the within-subject correlat... In this paper we use profile empirical likelihood to construct confidence regions for regression coefficients in partially linear model with longitudinal data. The main contribution is that the within-subject correlation is considered to improve estimation efficiency. We suppose a semi-parametric structure for the covariances of observation errors in each subject and employ both the first order and the second order moment conditions of the observation errors to construct the estimating equations. Although there are nonparametric variable in distribution after estimators, the empirical log-likelihood ratio statistic still tends to a standard Xp2 the nuisance parameters are profiled away. A data simulation is also conducted. 展开更多
关键词 partially linear model longitudinal data within-subject correlation empirical-likelihood
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ANALYSIS OF THE IMPACT OF SAMPLE SIZE, ATTRIBUTE VARIANCE AND WITHIN-SAMPLE CHOICE DISTRIBUTION ON THE ESTIMATION ACCURACY OF MULTINOMIAL LOGIT MODELS USING SIMULATED DATA 被引量:1
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作者 Minhui Zeng Ming Zhong John Douglas Hunt 《Journal of Systems Science and Systems Engineering》 SCIE EI CSCD 2018年第6期771-789,共19页
Literature review indicates that sample size, attribute variance and within-sample choice distribution of alternatives are important considerations in the estimation of multinomial logit (MNL) models, but their impa... Literature review indicates that sample size, attribute variance and within-sample choice distribution of alternatives are important considerations in the estimation of multinomial logit (MNL) models, but their impacts on the estimation accuracy have not been systematically studied. Therefore, the objective of this paper is to provide an empirical examination to the above issues through a set of simulated discrete choice preference and rank ordered preference datasets. In this paper, the utility coefficients, alternative specific constants (ASCs), and the mean and standard deviation of the four attributes for a set of seven hypothetical alternatives are specified as a priori. Then, synthetic datasets, with varying sample size, attribute variance and within-sample choice distribution are simulated. Based on these datasets, the utility coefficients and ASCs of the specified MNLs are re-estimated and compared with the original values specified as the priori. It is found that (1) the estimation accuracy of utility parameters increases as the sample size increases; (2) the utility coefficients can be re-estimated with reasonable accuracy, but the estimates of the ASCs are confronted with much larger errors; (3) as the variances of the alternative attributes increase, the estimation accuracy improves significantly; and (4) as the distribution of chosen choices becomes more balanced across alternatives within sample datasets, the hit-ratio decreases. The results indicate that (a) under a similar setting presented in this paper, a large sample consisting of a few thousand observations (3000 - 4000) may be needed in order to provide reasonable estimates for utility coefficients, particularly for ASCs; (b) a larger, but realistic attribute space is preferred in the stated preference survey design; and (c) choice datasets with unbalanced "chosen" choice frequency distribution is preferred, in order to better capture the elasticity between the "perceived utility" associated with alternative's attributes. 展开更多
关键词 Sample size attribute variance within-sample choice distribution simulated data
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银行业内卷化的系统性破解:困境溯源与转型路径重构
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作者 陆岷峰 《新疆师范大学学报(哲学社会科学版)》 北大核心 2026年第1期25-34,共10页
在金融供给侧结构性改革背景下,银行业内卷化已成为制度约束与市场行为双重异化的系统性问题。文本基于新制度经济学与组织行为学交叉分析,揭示其核心表征:同质化竞争导致资源错配、服务效能递减及人力资本耗散。通过构建“制度刚性、... 在金融供给侧结构性改革背景下,银行业内卷化已成为制度约束与市场行为双重异化的系统性问题。文本基于新制度经济学与组织行为学交叉分析,揭示其核心表征:同质化竞争导致资源错配、服务效能递减及人力资本耗散。通过构建“制度刚性、行为异化、技术锁定”三重嵌套模型发现:监管指标刚性化延长创新审批周期,六大行科技投入效率差异显著,银行类型呈现差异化内卷特征。不同类型银行的内卷化特征主要表现为:国有大行制度性内卷、股份制银行行为性内卷、城商行复合型困境。对此,文本提出“监管—市场—技术”协同治理框架,完善监管弹性激励机制、优化综合绩效评价体系、开放银行标准化建设。研究表明,“反内卷”转型要与金融科技伦理治理、绿色金融体系深度融合,推动银行业向“价值共创”生态转型,为构建新型金融生态提供科学的解决方案。 展开更多
关键词 银行业内卷化 制度变迁 监管沙盒 ESG评估 开放银行
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LIMIT LAWS OF LIFETIME FOR A CONSECUTIVE K-WITHIN-M-OUT-OF-N SYSTEM
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作者 QI Yongcheng(Department of Probobility and Statistics, Peking University, Beijing 100871, China) 《Systems Science and Mathematical Sciences》 SCIE EI CSCD 1994年第1期82-88,共7页
LIMITLAWSOFLIFETIMEFORACONSECUTIVEK-WITHIN-M-OUT-OF-NSYSTEM¥QIYongcheng(DepartmentofProbobilityandStatistics... LIMITLAWSOFLIFETIMEFORACONSECUTIVEK-WITHIN-M-OUT-OF-NSYSTEM¥QIYongcheng(DepartmentofProbobilityandStatistics,PekingUniversity... 展开更多
关键词 LIMIT TYPES RELIABILITY consecutive k-within-m-out-of-n system.
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平台型领导与变革型领导对制造业员工创新影响的比较研究
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作者 刘晖 钟佳怡 刘畅 《商业经济》 2026年第1期125-129,180,共6页
在制造业亟须通过员工创新突破技术变革与成本控制困境的背景下,平台型领导与变革型领导的作用差异成为管理实践的关键问题。本研究基于资源保存理论,收集246份制造企业员工有效问卷,对比分析两种领导风格对员工创新的差异化影响。研究... 在制造业亟须通过员工创新突破技术变革与成本控制困境的背景下,平台型领导与变革型领导的作用差异成为管理实践的关键问题。本研究基于资源保存理论,收集246份制造企业员工有效问卷,对比分析两种领导风格对员工创新的差异化影响。研究结果表明:平台型领导和变革型领导都对员工创新显著正向影响,其中平台型领导的促进作用更显著;职场精神力在平台型领导、变革型领导与员工创新关系间皆发挥部分中介作用,其中平台型领导更依赖资源支持,变革型领导更依赖愿景驱动;团队内竞争氛围对两种领导方式的调节效应截然相反:高竞争削弱平台型领导的作用(员工因资源争夺降低协作),却增强变革型领导的效果(以竞争性奖励激励员工)。 展开更多
关键词 平台型领导 变革型领导 职场精神力 团队内竞争氛围 员工创新
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Variation Within Trees of Wood Anatomical Properties in Chinese-Fir Plantation and Their Relationship Modeling Equations
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作者 Nakai Takashi 《Chinese Forestry Science and Technology》 2003年第2期5-15,共11页
A comprehensive analysis on the variation pattern of early- and latewood tracheid morphological parameters along tree (Cunninghamia lanceolata Hook.) height, including length and width, wall thickness, tissue proporti... A comprehensive analysis on the variation pattern of early- and latewood tracheid morphological parameters along tree (Cunninghamia lanceolata Hook.) height, including length and width, wall thickness, tissue proportion, cell wall percentage, width of growth rings, and on the relationship among them are conducted. The results indicate an initially rapid and then gentle increase of tracheid length and width, thickness of the radial wall and tangential wall of tracheid, area percentage of tracheid from pi... 展开更多
关键词 Chinese Fir variation within a tree anatomical properties growth rate correlation model
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冠心病患者PCI术后不同时间血清miR-93-5p、IL-25水平变化及其与冠状动脉ISR的关系 被引量:2
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作者 张立杰 王晓玲 +3 位作者 宋巧凤 贾洪娟 张振飞 周文华 《中南医学科学杂志》 2025年第1期110-113,共4页
目的探讨冠心病患者经皮冠状动脉介入(PCI)术后不同时间血清微小核糖核酸(miR)-93-5p、血清白细胞介素(IL)-25水平变化及其与冠状动脉支架内再狭窄(ISR)的关系。方法选取行PCI术的冠心病患者222例为研究对象,根据PCI术后复查冠状动脉造... 目的探讨冠心病患者经皮冠状动脉介入(PCI)术后不同时间血清微小核糖核酸(miR)-93-5p、血清白细胞介素(IL)-25水平变化及其与冠状动脉支架内再狭窄(ISR)的关系。方法选取行PCI术的冠心病患者222例为研究对象,根据PCI术后复查冠状动脉造影结果将其分为ISR组30例和非ISR组192例,检测所有患者术前1天和术后24 h、7天、6个月的血清miR-93-5p、IL-25水平并进行比较。采用多因素Logistic回归分析法分析ISR发生的相关影响因素。结果术后7天ISR组的IL-25水平高于非ISR组(P<0.05)。ISR组术后24 h、7天IL-25水平较术前1天升高(P<0.05);非ISR组术后24 h IL-25水平较术前升高(P<0.05)。术后7天ISR组的血清miR-93-5p水平低于非ISR组(P<0.05)。ISR组术后24 h、7天血清miR-93-5p水平较术前1天降低(P<0.05);非ISR组术后24 h血清miR-93-5p水平较术前1天降低(P<0.05)。术后24 h及术后7天的IL-25水平是ISR发生的危险因素,术后24 h及术后7天的miR-93-5p水平是ISR发生的保护因素(P<0.05)。结论血清miR-93-5p、IL-25水平可作为预测冠心病患者PCI术后ISR的参考指标。 展开更多
关键词 miR-93-5p 白细胞介素-25 经皮冠状动脉介入治疗 支架内再狭窄 影响因素
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浅析震源位置准确度及其影响因素 被引量:3
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作者 张风雪 李昱 陈泆平 《地球与行星物理论评(中英文)》 2025年第2期182-192,共11页
地震定位是地震学研究的基础,然而地震定位和地震学研究之间存在“供给”矛盾.不同研究对地震位置准确度级别的要求不尽相同,震源机制和壳幔结构研究要求震源位置的准确度为千米级别,工业生产活动和诱发地震研究要求震源位置的准确度为... 地震定位是地震学研究的基础,然而地震定位和地震学研究之间存在“供给”矛盾.不同研究对地震位置准确度级别的要求不尽相同,震源机制和壳幔结构研究要求震源位置的准确度为千米级别,工业生产活动和诱发地震研究要求震源位置的准确度为百米级别.然而,地震监测台网给出的地震位置准确度仅为数千米.诸多地震定位方法从不同方面对地震定位过程进行优化和改进,但它们的侧重点不尽相同.总体而言,已有的定位方法对地震位置的准确度关注程度尚显不足.在大量的地震定位实践中,前人获得了用于优化地震位置准确度的若干经验法则,这些经验法则不但存在地区差异,而且还有一定的适用条件,经验法则仍需要被进一步地优化和修正.本文简要分析地震定位准确度的多方面影响因素,有针对性地开展研究,在地震定位算法和控制观测数据质量方面获得一定的研究进展;在地震定位耦合关系方面补充了定位速度模型、发震位置和发震时刻三者之间的制约关系;在地震定位流程方面提出了使用逐步消元定位的建议. 展开更多
关键词 地震定位 震源位置准确度 网格搜索定位 观测数据质量 定位耦合关系
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高校二级学院有效治理:影响因素与优化策略 被引量:1
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作者 武蓓 徐刘香 郑昕郁 《江苏高教》 北大核心 2025年第4期70-78,共9页
二级学院是大学的核心基层组织,提升其治理效能是建立现代大学制度、实现大学治理能力现代化和高质量发展的关键。基于二级学院治理的生成性、模糊性和复杂性特点,研究选取某行业类高校学院的案例进行深入访谈与剖析,利用扎根理论进行... 二级学院是大学的核心基层组织,提升其治理效能是建立现代大学制度、实现大学治理能力现代化和高质量发展的关键。基于二级学院治理的生成性、模糊性和复杂性特点,研究选取某行业类高校学院的案例进行深入访谈与剖析,利用扎根理论进行编码分析,揭示了二级学院有效治理的影响因素:制度体系是核心因素,运行机制是保障因素,组织文化是驱动因素,领导力是关键因素。在此基础上,探讨各影响因素的动态演化关系,并通过构建关系模型探索学院治理效能持续提升的优化路径,以期为二级学院实现有效治理提供改革思路与实践参考。 展开更多
关键词 二级学院 治理效能 影响因素 院校治理
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AGEs、Apelin、Omentin-1与T2DM患者血糖在目标范围内时间的相关性及对并发微血管病变的预警能力研究 被引量:1
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作者 陈雪辉 尹清风 +4 位作者 孟祥雨 耿锐娜 王旭 徐云 白立炜 《海南医学》 2025年第1期82-86,共5页
目的研究血清晚期糖基化终末产物(AGEs)、爱帕琳肽(Apelin)、网膜素-1(Omentin-1)与2型糖尿病(T2DM)患者血糖在目标范围内时间(TIR)的相关性及对并发微血管病变的预警能力。方法前瞻性选取2021年5月至2024年6月新乡医学院第一附属医院... 目的研究血清晚期糖基化终末产物(AGEs)、爱帕琳肽(Apelin)、网膜素-1(Omentin-1)与2型糖尿病(T2DM)患者血糖在目标范围内时间(TIR)的相关性及对并发微血管病变的预警能力。方法前瞻性选取2021年5月至2024年6月新乡医学院第一附属医院收治的120例T2DM患者纳入研究,根据是否并发微血管病变分为并发组(n=52)和未并发组(n=68)。比较两组患者的基线资料和血清AGEs、Apelin、Omentin-1水平,采用Pearson相关性分析血清AGEs、Apelin、Omentin-1与TIR的相关性,采用多因素Logistic回归分析血清AGEs、Apelin、Omentin-1对T2DM并发微血管病变的影响,采用受试者工作特征(ROC)曲线及曲线下面积(AUC)评估血清AGEs、Apelin、Omentin-1对并发微血管病变的预警能力。结果并发组患者的T2DM病程为(9.01±1.35)年,明显长于未并发组的(8.53±1.24)年,糖化血红蛋白为(8.92±0.50)%,明显高于未并发组的(7.15±0.78)%,TIR为(46.73±10.22)%,明显低于未并发组的(68.82±7.61)%,差异均有统计学意义(P<0.05);并发组和未发生组患者的血清AGEs[(20.35±6.74)μg/mL vs(14.10±4.69)μg/mL]、Apelin[(6.20±2.03)ng/mL vs(4.19±1.27)ng/mL]比较,并发组明显高于未并发组,Omentin-1[(50.87±14.56)ng/mL vs(72.56±22.97)ng/mL]比较,并发组明显低于未发生组,差异均有统计学意义(P<0.05);Pearson相关性分析结果显示,血清AGEs、Apelin与TIR呈负相关(r=-0.759、-0.762,P<0.05),Omentin-1与TIR呈正相关(r=0.733,P<0.05);多因素Logistic回归分析结果显示,血清AGEs、Apelin、Omentin-1是T2DM并发微血管病变的独立相关影响因素(P<0.05);ROC曲线结果显示,血清AGEs、Apelin、Omentin-1单独及联合预测患者并发微血管病变的曲线下面积分别为0.787、0.798、0.796、0.935,联合预测价值更大。结论T2DM患者血清AGEs、Apelin、Omentin-1水平异常表达与TIR、并发微血管病变有关,三者联合有助于提高T2DM患者并发微血管病变的预测效能。 展开更多
关键词 2型糖尿病 晚期糖基化终末产物 爱帕琳肽 网膜素-1 血糖在目标范围内时间 微血管病变
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