Advancements in technology have led to a diversification of wound treatment methods,offering new possibilities for enhancing patient care.Though laser and light-emitting diodes(LEDs)phototherapy are common,they are ch...Advancements in technology have led to a diversification of wound treatment methods,offering new possibilities for enhancing patient care.Though laser and light-emitting diodes(LEDs)phototherapy are common,they are challenged for their downsides such as rigidity,bulkiness and overheating.However,organic light-emitting diodes(OLEDs)are recently in the limelight as a method of phototherapy that overcomes the existing shortcomings.A variety of wearable OLEDs have been developed using plastic substrates.These can provide phototherapy,but are not suitable for use in wounds where ooze forms.In this study,we report a platform combining OLEDs and hydrocolloid that accelerates wound healing,absorbs ooze,provides a moist environment to wound,and improves skin adhesion.This platform utilizes a proprietary planarization method to reduce the root-mean-square roughness(R_(q))value to 0.844 nm,and the luminescence performance of the device is also at the same level as that of a glass substrate device.In addition,we confirmed in-vitro cell proliferation effect of up to 160%at a luminous intensity of 5 mW/cm^(2),and experimentally demonstrated the moisture retention ability of hydrocolloid-based OLEDs for wounds in a pig skin model.This suggests that we have created an ehanced wound care platform.展开更多
基金supported by the Gachon University Research Fund in 2024(No.GCU−202406350001)supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),funded by the Ministry of Health&Welfare,Republic of Korea(No.HI22C0290)supported by a grant from Kyung Hee University in 2025.(No.KHU-20251312)。
文摘Advancements in technology have led to a diversification of wound treatment methods,offering new possibilities for enhancing patient care.Though laser and light-emitting diodes(LEDs)phototherapy are common,they are challenged for their downsides such as rigidity,bulkiness and overheating.However,organic light-emitting diodes(OLEDs)are recently in the limelight as a method of phototherapy that overcomes the existing shortcomings.A variety of wearable OLEDs have been developed using plastic substrates.These can provide phototherapy,but are not suitable for use in wounds where ooze forms.In this study,we report a platform combining OLEDs and hydrocolloid that accelerates wound healing,absorbs ooze,provides a moist environment to wound,and improves skin adhesion.This platform utilizes a proprietary planarization method to reduce the root-mean-square roughness(R_(q))value to 0.844 nm,and the luminescence performance of the device is also at the same level as that of a glass substrate device.In addition,we confirmed in-vitro cell proliferation effect of up to 160%at a luminous intensity of 5 mW/cm^(2),and experimentally demonstrated the moisture retention ability of hydrocolloid-based OLEDs for wounds in a pig skin model.This suggests that we have created an ehanced wound care platform.
