期刊文献+
共找到113,349篇文章
< 1 2 250 >
每页显示 20 50 100
Aqueous Ionic Liquid Mediated Hydrolysis of Native Corn Starch to Obtain Different Low Molecular Weight Starch
1
作者 YANG Rui WANG Xiaolin +1 位作者 DANG Qian LIU Zhengping 《高等学校化学学报》 北大核心 2026年第1期153-161,共9页
In this work,we proposed a strategy for the hydrolysis of native corn starch after the treatment of corn starch in an ionic liquid aqueous solution,and it is an awfully“green”and simple means to obtain starch with l... In this work,we proposed a strategy for the hydrolysis of native corn starch after the treatment of corn starch in an ionic liquid aqueous solution,and it is an awfully“green”and simple means to obtain starch with low molecular weight and amorphous state.X-ray diffraction results revealed that the natural starch crystalline region was largely disrupted by ionic liquid owing to the broken intermolecular and intramolecular hydrogen bonds.After hydrolysis,the morphology of starch changed from particles of native corn starch into little pieces,and their molecular weight could be effectively regulated during the hydrolysis process,and also the hydrolyzed starch samples exhibited decreased thermal stability with the extension of hydrolysis time.This work would counsel as a powerful tool for the development of native starch in realistic applications. 展开更多
关键词 Native corn starch Ionic liquid HYDROLYSIS Molecular weight
在线阅读 下载PDF
FedCW: Client Selection with Adaptive Weight in Heterogeneous Federated Learning
2
作者 Haotian Wu Jiaming Pei Jinhai Li 《Computers, Materials & Continua》 2026年第1期1551-1570,共20页
With the increasing complexity of vehicular networks and the proliferation of connected vehicles,Federated Learning(FL)has emerged as a critical framework for decentralized model training while preserving data privacy... With the increasing complexity of vehicular networks and the proliferation of connected vehicles,Federated Learning(FL)has emerged as a critical framework for decentralized model training while preserving data privacy.However,efficient client selection and adaptive weight allocation in heterogeneous and non-IID environments remain challenging.To address these issues,we propose Federated Learning with Client Selection and Adaptive Weighting(FedCW),a novel algorithm that leverages adaptive client selection and dynamic weight allocation for optimizing model convergence in real-time vehicular networks.FedCW selects clients based on their Euclidean distance from the global model and dynamically adjusts aggregation weights to optimize both data diversity and model convergence.Experimental results show that FedCW significantly outperforms existing FL algorithms such as FedAvg,FedProx,and SCAFFOLD,particularly in non-IID settings,achieving faster convergence,higher accuracy,and reduced communication overhead.These findings demonstrate that FedCW provides an effective solution for enhancing the performance of FL in heterogeneous,edge-based computing environments. 展开更多
关键词 Federated learning non-IID client selection weight allocation vehicular networks
在线阅读 下载PDF
Self-Learning and Its Application to Laminar Cooling Model of Hot Rolled Strip 被引量:16
3
作者 GONG Dian-yao XU Jian-zhong PENG Liang-gui WANG Guo-dong LIU Xiang-hua 《Journal of Iron and Steel Research International》 SCIE EI CAS CSCD 2007年第4期11-14,共4页
The mathematical model for online controlling hot rolled steel cooling on run-out table (ROT for abbreviation) was analyzed, and water cooling is found to be the main cooling mode for hot rolled steel. The calculati... The mathematical model for online controlling hot rolled steel cooling on run-out table (ROT for abbreviation) was analyzed, and water cooling is found to be the main cooling mode for hot rolled steel. The calculation of the drop in strip temperature by both water cooling and air cooling is summed up to obtain the change of heat transfer coefficient. It is found that the learning coefficient of heat transfer coefficient is the kernel coefficient of coiler temperature control (CTC) model tuning. To decrease the deviation between the calculated steel temperature and the measured one at coiler entrance, a laminar cooling control self-learning strategy is used. Using the data acquired in the field, the results of the self-learning model used in the field were analyzed. The analyzed results show that the self-learning function is effective. 展开更多
关键词 laminar cooling hot rolled strip self-learning process control model
在线阅读 下载PDF
Long-and Short-Term Self-Learning Models of Rolling Force in Rolling Process Without Gaugemeter of Plate 被引量:3
4
作者 ZHU Fu-wen ZENG Qing-liang +2 位作者 HU Xian-lei LI Xi-an LIU Xiang-hua 《Journal of Iron and Steel Research International》 SCIE EI CAS CSCD 2009年第1期27-31,61,共6页
Owing to a lack of gaugemeter and the variety of steel grades and standards in some plate mills, the longand short-term self-learning models of rolling force based on gauge soft-measuring with high precision were brou... Owing to a lack of gaugemeter and the variety of steel grades and standards in some plate mills, the longand short-term self-learning models of rolling force based on gauge soft-measuring with high precision were brought up. The soft-measuring method and target value locked method were used in these models to confirm the actual exit gauge of passes, and thick layer division and exponential smoothing method were used to dispose the deformation resistance parameter, which could be calculated from the actual data of the rolling process. The correlative mathematical methods can also be adapted to self-learning with gaugemeter. The models were applied to the process control system of AGC (automatic gauge control) reconstruction on 2800 mm finishing mill of Anyang steel and favorable effect was obtained. 展开更多
关键词 PLATE self-learning soft measuring rolling force
原文传递
Application of Self-Learning to Heating Process Control of Simulated Continuous Annealing 被引量:2
5
作者 WANG Wen-le LI Jian-ping HUA Fu-an LIUXiang-hua 《Journal of Iron and Steel Research International》 SCIE EI CAS CSCD 2010年第6期27-31,共5页
On the basis of a simulated bright continuous annealing experimental machine, a process control model for heating system was built. The heating model was simplified and self-learning parameters were normalized to enha... On the basis of a simulated bright continuous annealing experimental machine, a process control model for heating system was built. The heating model was simplified and self-learning parameters were normalized to enhance the precision of temperature control. By means of the division of temperature layers and the exponential smoothing disposal of the annealing experimental data, the self-learning of the heating model was carried out. Through exponentially smoothing the deviation of self-learning parameters of the heated phase in heating process, dynamic modifications of self-learning parameters and heating electric current were carried out, and the precision of temperature control was confirmed. The application indicated that the process control model for the heating system can control temperature with high precision, and the deviation can be controlled within 8 ℃. 展开更多
关键词 ANNEALING SIMULATION annealing maehine process control self-learning
原文传递
Self-Learning of Multivariate Time Series Using Perceptually Important Points 被引量:2
6
作者 Timo Lintonen Tomi Raty 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2019年第6期1318-1331,共14页
In machine learning,positive-unlabelled(PU)learning is a special case within semi-supervised learning.In positiveunlabelled learning,the training set contains some positive examples and a set of unlabelled examples fr... In machine learning,positive-unlabelled(PU)learning is a special case within semi-supervised learning.In positiveunlabelled learning,the training set contains some positive examples and a set of unlabelled examples from both the positive and negative classes.Positive-unlabelled learning has gained attention in many domains,especially in time-series data,in which the obtainment of labelled data is challenging.Examples which originate from the negative class are especially difficult to acquire.Self-learning is a semi-supervised method capable of PU learning in time-series data.In the self-learning approach,observations are individually added from the unlabelled data into the positive class until a stopping criterion is reached.The model is retrained after each addition with the existent labels.The main problem in self-learning is to know when to stop the learning.There are multiple,different stopping criteria in the literature,but they tend to be inaccurate or challenging to apply.This publication proposes a novel stopping criterion,which is called Peak evaluation using perceptually important points,to address this problem for time-series data.Peak evaluation using perceptually important points is exceptional,as it does not have tunable hyperparameters,which makes it easily applicable to an unsupervised setting.Simultaneously,it is flexible as it does not make any assumptions on the balance of the dataset between the positive and the negative class. 展开更多
关键词 Positive-unlabelled(PU) learning self-learning stopping criterion time series
在线阅读 下载PDF
Sensorimotor Self-Learning Model Based on Operant Conditioning for Two-Wheeled Robot 被引量:1
7
作者 张晓平 阮晓钢 +1 位作者 肖尧 黄静 《Journal of Shanghai Jiaotong university(Science)》 EI 2017年第2期148-155,共8页
Traditional control methods of two-wheeled robot are usually model-based and require the robot’s precise mathematic model which is hard to get. A sensorimotor self-learning model named SMM TWR is presented in this pa... Traditional control methods of two-wheeled robot are usually model-based and require the robot’s precise mathematic model which is hard to get. A sensorimotor self-learning model named SMM TWR is presented in this paper to handle these problems. The model consists of seven elements: the discrete learning time set, the sensory state set, the motion set, the sensorimotor mapping, the state orientation unit, the learning mechanism and the model’s entropy. The learning mechanism for SMM TWR is designed based on the theory of operant conditioning (OC), and it adjusts the sensorimotor mapping at every learning step. This helps the robot to choose motions. The leaning direction of the mechanism is decided by the state orientation unit. Simulation results show that with the sensorimotor model designed, the robot is endowed the abilities of self-learning and self-organizing, and it can learn the skills to keep itself balance through interacting with the environment. © 2017, Shanghai Jiaotong University and Springer-Verlag Berlin Heidelberg. 展开更多
关键词 two-wheeled robot sensorimotor model self-learning operant conditioning(OC)
原文传递
Where Have Network-based Self-learning Classes Gone?——Reflections & Expectations on the Employment of Network-based Self-learning Classes
8
作者 吴雪茵 《海外英语》 2012年第18期279-280,共2页
To respond to the further development of college English reforms,many universities employed network-based selflearning classes to aid the traditional classroom teaching,especially in teaching listening,but as time wen... To respond to the further development of college English reforms,many universities employed network-based selflearning classes to aid the traditional classroom teaching,especially in teaching listening,but as time went by,some universities gradually gave them up.The paper intends to reflect on the employment of network-based self-learning listening classes,analyz ing the learning with and without its aid,and meanwhile introduce the need to re-employ it,and discuss how we can improve the network-based self-learning classes to help with students' listening. 展开更多
关键词 NETWORK-BASED self-learning LISTENING improvement
在线阅读 下载PDF
SELF-LEARNING FUZZY CONTROL RULES USING GENETIC ALGORITHMS
9
作者 方建安 邵世煌 《Journal of China Textile University(English Edition)》 EI CAS 1995年第1期7-13,共7页
This papcr presents a new genetic algorithms(GAs)-based method for self-learniag fuzzy control rules. An improved GA is used to learn to optimally select the fuzzy membership functions of the linguistic labels in the ... This papcr presents a new genetic algorithms(GAs)-based method for self-learniag fuzzy control rules. An improved GA is used to learn to optimally select the fuzzy membership functions of the linguistic labels in the condition portion of each rule, and to automatically generate fuzzy control actions under each condition. The dynamics of the controlled system is unknown to the GA. The only information for evaluating performance is a failure signal indicating that the controlled system is out of control. We compare its performance with that of other learning methods for the same problem. We also examine the ability of the algorithm to adapt to changing conditions. Simulation results show that such an approach for self-learning fuzzy control rules is both effective and robust. 展开更多
关键词 GENETIC ALGORITHM self-learning FUZZY control.
在线阅读 下载PDF
Mathematical model for cooling process and its self-learning applied in hot rolling mill
10
作者 刘伟嵬 李海军 +1 位作者 王昭东 王国栋 《Journal of Shanghai University(English Edition)》 CAS 2011年第6期548-552,共5页
Control precision of coiling temperature is one of the key factors affecting the profile shape and surface quality during the cooling process of hot rolled steel strip.For this reason,the core of temperature control p... Control precision of coiling temperature is one of the key factors affecting the profile shape and surface quality during the cooling process of hot rolled steel strip.For this reason,the core of temperature control precision is to establish an effective cooling mathematical model with self-learning function.Starting from this point,a cooling mathematical model with nonlinear structural characteristics is established in this paper for the cooling process of hot rolled steel strip.By the analysis of self-learning ability,key parameters of the mathematical model could be constantly corrected so as to improve temperature control precision and adaptive capability of the model.The site actual application results proved the stable performance and high control precision of the proposed mathematical model,which would lay a solid foundation to improve the steel product qualities. 展开更多
关键词 cooling process MODEL coiling temperature self-learning hot rolled steel strip
在线阅读 下载PDF
Study on intelligent digital welding machine with a self-learning function
11
作者 张晓莉 朱强 +2 位作者 李钰桢 龙鹏 薛家祥 《China Welding》 EI CAS 2013年第4期74-80,共7页
A design idea was proposed that it was about intelligent digital welding machine with self-learning and self- regulation functions. The overall design scheme of software and hardware was provided. It was introduced th... A design idea was proposed that it was about intelligent digital welding machine with self-learning and self- regulation functions. The overall design scheme of software and hardware was provided. It was introduced that a parameter self-learning algorithm was based on large-step calibration and partial Newton interpolation. Furthermore, experimental verification was carried out with different welding technologies. The results show that weld bead is pegrect. Therefore, good welding quality and stability are obtained, and intelligent regulation is realized by parameters self-learning. 展开更多
关键词 intelligent digital welding machine self-learning large-step calibration
在线阅读 下载PDF
Self-learning Fuzzy Controllers Based On a Real-time Reinforcement Genetic Algorithm
12
作者 方建安 苗清影 +1 位作者 郭钊侠 邵世煌 《Journal of Donghua University(English Edition)》 EI CAS 2002年第2期19-22,共4页
This paper presents a novel method for constructing fuzzy controllers based on a real time reinforcement genetic algorithm. This methodology introduces the real-time learning capability of neural networks into globall... This paper presents a novel method for constructing fuzzy controllers based on a real time reinforcement genetic algorithm. This methodology introduces the real-time learning capability of neural networks into globally searching process of genetic algorithm, aiming to enhance the convergence rate and real-time learning ability of genetic algorithm, which is then used to construct fuzzy controllers for complex dynamic systems without any knowledge about system dynamics and prior control experience. The cart-pole system is employed as a test bed to demonstrate the effectiveness of the proposed control scheme, and the robustness of the acquired fuzzy controller with comparable result. 展开更多
关键词 fuzzy controller self-learning REAL time reinforcement GENETIC algorithm
在线阅读 下载PDF
Neuron self-learning PSD control for backside width of weld pool in pulsed GTAW with wire filler
13
作者 张广军 陈善本 吴林 《China Welding》 EI CAS 2003年第2期87-91,共5页
In this paper, the weld pool shape control by intelligent strategy was studied. A neuron self-learning PSD controller for backside width of weld pool in pulsed GTAW with wire filler was designed. The PSD control arith... In this paper, the weld pool shape control by intelligent strategy was studied. A neuron self-learning PSD controller for backside width of weld pool in pulsed GTAW with wire filler was designed. The PSD control arithmetic was analyzed, simulating experiment by MATLAB software was done, and the validating experiments on varied heat sink workpiece and varied gap workpiece were successfully implemented. The study results show that the neuron self-learning PSD control method can attain a perfect control effect under different set values and conditions, and is suitable for the welding process with the varied structure and coefficients of control model. 展开更多
关键词 pulsed GTAW with wire filler backside width control intelligent control neuron self-learning PSD
在线阅读 下载PDF
Combing the Entropy Weight Method with Fuzzy Mathematics for Assessing the Quality and Post-Ripening Mechanism of High-Temperature Daqu during Storage 被引量:1
14
作者 YANG Junlin YANG Shaojuan +8 位作者 WU Cheng YIN Yanshun YOU Xiaolong ZHAO Wenyu ZHU Anran WANG Jia HU Feng HU Jianfeng WANG Diqiang 《食品科学》 北大核心 2025年第9期48-62,共15页
This study investigated the physicochemical properties,enzyme activities,volatile flavor components,microbial communities,and sensory evaluation of high-temperature Daqu(HTD)during the maturation process,and a standar... This study investigated the physicochemical properties,enzyme activities,volatile flavor components,microbial communities,and sensory evaluation of high-temperature Daqu(HTD)during the maturation process,and a standard system was established for comprehensive quality evaluation of HTD.There were obvious changes in the physicochemical properties,enzyme activities,and volatile flavor components at different storage periods,which affected the sensory evaluation of HTD to a certain extent.The results of high-throughput sequencing revealed significant microbial diversity,and showed that the bacterial community changed significantly more than did the fungal community.During the storage process,the dominant bacterial genera were Kroppenstedtia and Thermoascus.The correlation between dominant microorganisms and quality indicators highlighted their role in HTD quality.Lactococcus,Candida,Pichia,Paecilomyces,and protease activity played a crucial role in the formation of isovaleraldehyde.Acidic protease activity had the greatest impact on the microbial community.Moisture promoted isobutyric acid generation.Furthermore,the comprehensive quality evaluation standard system was established by the entropy weight method combined with multi-factor fuzzy mathematics.Consequently,this study provides innovative insights for comprehensive quality evaluation of HTD during storage and establishes a groundwork for scientific and rational storage of HTD and quality control of sauce-flavor Baijiu. 展开更多
关键词 microbial community high-temperature Daqu comprehensive quality evaluation entropy weight method maturation process
在线阅读 下载PDF
The Self-Learning Gate for Quantum Computing
15
作者 Abdullah Ibrahim S. Alsalman 《Journal of Quantum Information Science》 2022年第1期21-28,共8页
Self-learning is one of the most important scientific methods that helps develop sciences, as it derives from the desire and interests of the individual. However, self-learning loses importance if it does not follow t... Self-learning is one of the most important scientific methods that helps develop sciences, as it derives from the desire and interests of the individual. However, self-learning loses importance if it does not follow the scientific methodology for building and organizing information. The case becomes harder if the science is new and few scientific sources are available. Quantum computing is one of the new sciences in computer science and needs the support of specialists to develop it. Quantum computing overlaps with many sciences such as physics, chemistry, and mathematics, so any student in one of the previous disciplines may lose the correct self-learning path to find themselves learning the details of another discipline that does not achieve their goals. This article motivates students and those interested in computer science to begin studying the science of quantum computing and choose the same specialization that suits their interests. The article also provides a roadmap for self-learning steps to protect the learner from losing the correct learning path. I have categorized the stages of learning quantum computing into four steps through which all the essential basics can be learned, provided the goals mentioned in each stage which should be achieved. The learning strategy proposed in this article corresponds with individuals’ self-learning rules. Through my personal experience, the proposed learning strategy has proven its effectiveness in building information in an enjoyable scientific way. 展开更多
关键词 Quantum Computing Computer Science self-learning Technology Revolution
在线阅读 下载PDF
A novel self-learning approach to overcome incompatibility on TripAdvisor reviews
16
作者 Prarthana Abeysinghe Thushara Bandara 《Data Science and Management》 2022年第1期1-10,共10页
Among social media networks,TripAdvisor acts as the main role because everyone is eager to share and review their thoughts on their travel experiences in different destinations.Sentiment analysis is amethod that can b... Among social media networks,TripAdvisor acts as the main role because everyone is eager to share and review their thoughts on their travel experiences in different destinations.Sentiment analysis is amethod that can be used to analyze people's behaviors and opinions onpublic and socialmedia platforms.In this study,hotel reviews are extracted fromthe five most attractive Sri Lankan cities,and user-written reviews are compared over user bubble ratings,which define overall travelers'experiences as a numerical scale that ranks from 1 to 5.We find that the compatibility between userwritten reviews and bubble ratings has a low correlation because bubble ratings may not represent the overall idea of users'genuine opinions expressed in their reviews.To address this problem,a two-phase approach is proposed:(1)the ensemblemethod to improve the performance of lexicon-based outputs and identify the correctlymatching user review and bubble rating;(2)the self-learning approach to finding the sentiment of a review that does not properly label by the user.The performance is studied by considering reviews incompatible with the sentiment of user bubble rating and the sentiment generated by the proposedmodel.For example,regardless of bigram“not good”,the average percentages of the word“good”for each negatively identified review from the proposed model and bubble rating are 25.63%and 38.85%,respectively.Thereby,it is apparent that the negative sentiments derived by bubble rating have significantly more positive words compared to the proposed model. 展开更多
关键词 ALGORITHMS Sentiment analysis Social media TripAdvisor self-learning
在线阅读 下载PDF
A Self-Learning Diagnosis Algorithm Based on Data Clustering
17
作者 Dmitry Tretyakov 《Intelligent Control and Automation》 2016年第3期84-92,共9页
The article describes an approach to building a self-learning diagnostic algorithm. The self-learning algorithm creates models of the object under consideration. The models are formed periodically through a certain ti... The article describes an approach to building a self-learning diagnostic algorithm. The self-learning algorithm creates models of the object under consideration. The models are formed periodically through a certain time period. The model includes a set of functions that can describe whole object, or a part of the object, or a specified functionality of the object. Thus, information about fault location can be obtained. During operation of the object the algorithm collects data received from sensors. Then the algorithm creates samples related to steady state operation. Clustering of those samples is used for the functions definition. Values of the functions in the centers of clusters are stored in the computer’s memory. To illustrate the considered approach, its application to the diagnosis of turbomachines is described. 展开更多
关键词 self-learning Diagnostics Fault Detection CLUSTERS K-MEANS Turbomachine Gas Turbine Centrifugal Supercharger Gas Compressor Unit
在线阅读 下载PDF
Stability Prediction in Smart Grid Using PSO Optimized XGBoost Algorithm with Dynamic Inertia Weight Updation
18
作者 Adel Binbusayyis Mohemmed Sha 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期909-931,共23页
Prediction of stability in SG(Smart Grid)is essential in maintaining consistency and reliability of power supply in grid infrastructure.Analyzing the fluctuations in power generation and consumption patterns of smart ... Prediction of stability in SG(Smart Grid)is essential in maintaining consistency and reliability of power supply in grid infrastructure.Analyzing the fluctuations in power generation and consumption patterns of smart cities assists in effectively managing continuous power supply in the grid.It also possesses a better impact on averting overloading and permitting effective energy storage.Even though many traditional techniques have predicted the consumption rate for preserving stability,enhancement is required in prediction measures with minimized loss.To overcome the complications in existing studies,this paper intends to predict stability from the smart grid stability prediction dataset using machine learning algorithms.To accomplish this,pre-processing is performed initially to handle missing values since it develops biased models when missing values are mishandled and performs feature scaling to normalize independent data features.Then,the pre-processed data are taken for training and testing.Following that,the regression process is performed using Modified PSO(Particle Swarm Optimization)optimized XGBoost Technique with dynamic inertia weight update,which analyses variables like gamma(G),reaction time(tau1–tau4),and power balance(p1–p4)for providing effective future stability in SG.Since PSO attains optimal solution by adjusting position through dynamic inertial weights,it is integrated with XGBoost due to its scalability and faster computational speed characteristics.The hyperparameters of XGBoost are fine-tuned in the training process for achieving promising outcomes on prediction.Regression results are measured through evaluation metrics such as MSE(Mean Square Error)of 0.011312781,MAE(Mean Absolute Error)of 0.008596322,and RMSE(Root Mean Square Error)of 0.010636156 and MAPE(Mean Absolute Percentage Error)value of 0.0052 which determine the efficacy of the system. 展开更多
关键词 Smart Grid machine learning particle swarm optimization XGBoost dynamic inertia weight update
在线阅读 下载PDF
Association Between Low Birth Weight and Dementia Risk:A Large-scale Prospective Study
19
作者 YU Xinyue XUE Qingping +10 位作者 LI Jingyi ZHANG Peiqi OUYANG Qingqing LUO Xiaoxue HE Qian WANG Yongliu ZHAO Ying HE Xiangwang LI Fan YANG Yunhaonan PAN Xiongfei 《四川大学学报(医学版)》 北大核心 2025年第3期697-710,共14页
Objective To investigate the association between birth weight and dementia risk and the mediating roles of chronic diseases,and to assess potential biological pathways underlying the birth weight-associated dementia r... Objective To investigate the association between birth weight and dementia risk and the mediating roles of chronic diseases,and to assess potential biological pathways underlying the birth weight-associated dementia risk based on large-scale proteomics.Methods We used data from 279743 participants aged 40 to 69 years enrolled in the UK Biobank.Birth weight was categorized into low birth weight(≤2500 g),normal birth weight(2500-3999 g),and macrosomia(≥4000 g).Multivariable Cox proportional hazards regression models were used to assess the associations between birth weight categories and all-cause dementia and its subtypes(Alzheimer's disease and vascular dementia).Proteomics analyses were conducted to identify proteins and the potential pathways involved.Results Low birth weight was associated with higher risks for all-cause dementia and its subtypes.The hazard ratios were 1.18(95%CI,1.08-1.30)for all-cause dementia,1.14(95%CI,1.00-1.31)for Alzheimer's disease,and 1.22(95%CI,1.01-1.48)for vascular dementia.A non-linear relationship was observed between birth weight and dementia risk(P for nonlinearity<0.001).Certain cardiometabolic diseases in middle-aged adults,such as diabetes,stroke,hypertension,and dyslipidemia,played a significant mediating role in the relationship between low birth weight and dementia risk,with the mediation proportion being 6.3%to 15.8%.Proteomic analyses identified 21 proteins linked to both low birth weight and all-cause dementia risk,which were significantly enriched in the pathways for viral protein interaction with cytokines and cytokine receptors,adipocytokine signaling,and cytokine-cytokine receptor interaction.Conclusion Low birth weight is positively associated with dementia risk.Cardiometabolic diseases in middle-aged adults may mediate the relationship between low birth weight and dementia risk.A number of proteins and the associated pathways underscore the relationship between low birth weight and dementia risk. 展开更多
关键词 Birth weight DEMENTIA PROTEOMICS Alzheimer's disease Vascular dementia
原文传递
上一页 1 2 250 下一页 到第
使用帮助 返回顶部