Using daily BTC-USD data from September 19,2014 to January 21,2024,this paper re-examines whether weekends differ from weekdays for Bitcoin along three margins:average returns,close-to-close volatility,and trading act...Using daily BTC-USD data from September 19,2014 to January 21,2024,this paper re-examines whether weekends differ from weekdays for Bitcoin along three margins:average returns,close-to-close volatility,and trading activity.We implement Welch mean comparisons and HAC-robust OLS with month fixed effects(bandwidths 5,7,and 14).In the full sample and across subsamples(2016–2019;2020–2023;early 2024),we find no detectable weekend–weekday gap in average returns,while volatility and trading activity are lower on weekends.The patterns are robust to using squared returns as a volatility proxy.The joint evidence is consistent with liquidity and attention mechanisms—quieter weekends rather than compensating return premia.Replication files reproduce all tables and figures.展开更多
AIM:To evaluate whether weekend or nighttime admission affects prognosis of peptic ulcer bleeding despite early endoscopy.METHODS:Retrospective data collection from four referral centers,all of which had a formal out-...AIM:To evaluate whether weekend or nighttime admission affects prognosis of peptic ulcer bleeding despite early endoscopy.METHODS:Retrospective data collection from four referral centers,all of which had a formal out-of-hours emergency endoscopy service,even at weekends.A total of 388 patients with bleeding peptic ulcers who were admitted via the emergency room between January 2007 and December 2009 were enrolled.Analyzed parameters included time from patients' arrival until endoscopy,mortality,rebleeding,need for surgery and length of hospital stay.RESULTS:The weekday and weekend admission groups comprised 326 and 62 patients,respectively.There were no significant differences in baseline characteristics between the two groups,except for younger age in the weekend group.Most patients (97%) had undergone early endoscopy,which resulted in a low mortality rate regardless of point of presentation (1.8% overall vs 1.6% on the weekend).The only outcome that was worse in the weekend group was a higher rate of rebleeding (12% vs 21%,P = 0.030).However,multivariate analysis revealed nighttime admission and a high Rockall score (≥ 6) as significant independent risk factors for rebleeding,rather than weekend admission.CONCLUSION:Early endoscopy for peptic ulcer bleeding can prevent the weekend effect,and nighttime admission was identified as a novel risk factor for rebleeding,namely the nighttime effect.展开更多
文摘Using daily BTC-USD data from September 19,2014 to January 21,2024,this paper re-examines whether weekends differ from weekdays for Bitcoin along three margins:average returns,close-to-close volatility,and trading activity.We implement Welch mean comparisons and HAC-robust OLS with month fixed effects(bandwidths 5,7,and 14).In the full sample and across subsamples(2016–2019;2020–2023;early 2024),we find no detectable weekend–weekday gap in average returns,while volatility and trading activity are lower on weekends.The patterns are robust to using squared returns as a volatility proxy.The joint evidence is consistent with liquidity and attention mechanisms—quieter weekends rather than compensating return premia.Replication files reproduce all tables and figures.
文摘AIM:To evaluate whether weekend or nighttime admission affects prognosis of peptic ulcer bleeding despite early endoscopy.METHODS:Retrospective data collection from four referral centers,all of which had a formal out-of-hours emergency endoscopy service,even at weekends.A total of 388 patients with bleeding peptic ulcers who were admitted via the emergency room between January 2007 and December 2009 were enrolled.Analyzed parameters included time from patients' arrival until endoscopy,mortality,rebleeding,need for surgery and length of hospital stay.RESULTS:The weekday and weekend admission groups comprised 326 and 62 patients,respectively.There were no significant differences in baseline characteristics between the two groups,except for younger age in the weekend group.Most patients (97%) had undergone early endoscopy,which resulted in a low mortality rate regardless of point of presentation (1.8% overall vs 1.6% on the weekend).The only outcome that was worse in the weekend group was a higher rate of rebleeding (12% vs 21%,P = 0.030).However,multivariate analysis revealed nighttime admission and a high Rockall score (≥ 6) as significant independent risk factors for rebleeding,rather than weekend admission.CONCLUSION:Early endoscopy for peptic ulcer bleeding can prevent the weekend effect,and nighttime admission was identified as a novel risk factor for rebleeding,namely the nighttime effect.
